Organism Overview: Moranella endobia


 
lepA protein networkhttps://string-db.org/network/903503.MEPCIT_001GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
lepB protein networkhttps://string-db.org/network/903503.MEPCIT_002Signal peptidase I; Predicted based on similarity to TIGRFAM sigpep_I_bact and related proteins in nr; Belongs to the peptidase S26 family.
rnc protein networkhttps://string-db.org/network/903503.MEPCIT_003Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
era protein networkhttps://string-db.org/network/903503.MEPCIT_004GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly als [...]
acpS protein networkhttps://string-db.org/network/903503.MEPCIT_005Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
mnmE protein networkhttps://string-db.org/network/903503.MEPCIT_012tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
yidC protein networkhttps://string-db.org/network/903503.MEPCIT_013Putative inner membrane protein translocase component YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in [...]
rnpA protein networkhttps://string-db.org/network/903503.MEPCIT_014Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein compo [...]
rpmH protein networkhttps://string-db.org/network/903503.MEPCIT_01550S ribosomal protein L34; Predicted based on similarity to TIGRFAM rpmH_bact and related proteins in nr; Belongs to the bacterial ribosomal protein bL34 family.
priA protein networkhttps://string-db.org/network/903503.MEPCIT_016Primosome factor N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its hel [...]
rpmE protein networkhttps://string-db.org/network/903503.MEPCIT_017Putative 50S ribosomal protein L31; Binds the 23S rRNA.
dnaN protein networkhttps://string-db.org/network/903503.MEPCIT_018DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadi [...]
gyrB protein networkhttps://string-db.org/network/903503.MEPCIT_019DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
cspD protein networkhttps://string-db.org/network/903503.MEPCIT_022Putative cold shock-like protein CspD; Predicted based on similarity to TIGRFAM cspD and related proteins in nr.
engB protein networkhttps://string-db.org/network/903503.MEPCIT_023Putative ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like G [...]
dnaB protein networkhttps://string-db.org/network/903503.MEPCIT_024Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
ssb protein networkhttps://string-db.org/network/903503.MEPCIT_025Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of actio [...]
hemD protein networkhttps://string-db.org/network/903503.MEPCIT_026uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
hemC protein networkhttps://string-db.org/network/903503.MEPCIT_027Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
uvrD protein networkhttps://string-db.org/network/903503.MEPCIT_028DNA-dependent helicase II; Predicted based on similarity to TIGRFAM uvrD and related proteins in nr.
cysS protein networkhttps://string-db.org/network/903503.MEPCIT_031cysteinyl-tRNA synthetase; Predicted based on similarity to TIGRFAM cysS and related proteins in nr; Belongs to the class-I aminoacyl-tRNA synthetase family.
hspQ protein networkhttps://string-db.org/network/903503.MEPCIT_032Putative hemimethylated DNA binding protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.
bacA protein networkhttps://string-db.org/network/903503.MEPCIT_033Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
cca protein networkhttps://string-db.org/network/903503.MEPCIT_0342',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the or [...]
AEI74700.1 protein networkhttps://string-db.org/network/903503.MEPCIT_035Putative monothiol glutaredoxin; Predicted based on similarity to TIGRFAM TIGR00365 and related proteins in nr; Belongs to the glutaredoxin family. Monothiol subfamily.
rnt protein networkhttps://string-db.org/network/903503.MEPCIT_036RNase T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue [...]
AEI74702.1 protein networkhttps://string-db.org/network/903503.MEPCIT_037Putative enoyl-(acyl carrier protein) reductase; Predicted based on similarity to TIGRFAM 3oxo_ACP_reduc and related proteins in nr.
ppa protein networkhttps://string-db.org/network/903503.MEPCIT_038Putative inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
AEI74704.1 protein networkhttps://string-db.org/network/903503.MEPCIT_039Putative cation:proton antiport protein; Predicted based on similarity to TIGRFAM 2a37 and related proteins in nr; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A. [...]
dapA protein networkhttps://string-db.org/network/903503.MEPCIT_040Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
trxA protein networkhttps://string-db.org/network/903503.MEPCIT_041Thioredoxin; Predicted based on similarity to TIGRFAM thioredoxin and related proteins in nr; Belongs to the thioredoxin family.
rho protein networkhttps://string-db.org/network/903503.MEPCIT_042Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
AEI74708.1 protein networkhttps://string-db.org/network/903503.MEPCIT_047Uncharacterized lipoprotein; Predicted based on similarity to TIGRFAM lp_ and related proteins in nr.
AEI74709.1 protein networkhttps://string-db.org/network/903503.MEPCIT_048Conserved hypothetical protein MEPCIT_048; Predicted based on similarity to related proteins in nr.
gapA protein networkhttps://string-db.org/network/903503.MEPCIT_049Glyceraldehyde 3-phosphate dehydrogenase; Predicted based on similarity to TIGRFAM GAPDH-I and related proteins in nr; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
cspD-2 protein networkhttps://string-db.org/network/903503.MEPCIT_050Putative major cold shock protein; Predicted based on similarity to TIGRFAM cspD and related proteins in nr.
trpS protein networkhttps://string-db.org/network/903503.MEPCIT_051tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
ksgA protein networkhttps://string-db.org/network/903503.MEPCIT_052Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
pdxA protein networkhttps://string-db.org/network/903503.MEPCIT_0534-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decar [...]
surA protein networkhttps://string-db.org/network/903503.MEPCIT_054Putative peptidyl-prolyl cis-trans isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the ori [...]
lptD protein networkhttps://string-db.org/network/903503.MEPCIT_055Conserved hypothetical protein MEPCIT_055; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
dut protein networkhttps://string-db.org/network/903503.MEPCIT_056Putative deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases th [...]
rpmB protein networkhttps://string-db.org/network/903503.MEPCIT_05750S ribosomal protein L28; Predicted based on similarity to TIGRFAM L28 and related proteins in nr; Belongs to the bacterial ribosomal protein bL28 family.
rpmG protein networkhttps://string-db.org/network/903503.MEPCIT_05850S ribosomal protein L33; Predicted based on similarity to TIGRFAM rpmG_bact and related proteins in nr; Belongs to the bacterial ribosomal protein bL33 family.
mutM protein networkhttps://string-db.org/network/903503.MEPCIT_059formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a [...]
dnaX protein networkhttps://string-db.org/network/903503.MEPCIT_060DNA polymerase III gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' t [...]
adk protein networkhttps://string-db.org/network/903503.MEPCIT_061Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
nuoN protein networkhttps://string-db.org/network/903503.MEPCIT_062Putative NADH dehydrogenase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoM protein networkhttps://string-db.org/network/903503.MEPCIT_063Putative NADH dehydrogenase subunit M; Predicted based on similarity to TIGRFAM NDH_I_M and related proteins in nr.
nuoL protein networkhttps://string-db.org/network/903503.MEPCIT_064Putative NADH dehydrogenase subunit L; Predicted based on similarity to TIGRFAM NDH_I_L and related proteins in nr.
nuoK protein networkhttps://string-db.org/network/903503.MEPCIT_065Putative NADH dehydrogenase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoJ protein networkhttps://string-db.org/network/903503.MEPCIT_066Putative NADH dehydrogenase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton trans [...]
nuoI protein networkhttps://string-db.org/network/903503.MEPCIT_067Putative NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoH protein networkhttps://string-db.org/network/903503.MEPCIT_068Putative NADH dehydrogenase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoG protein networkhttps://string-db.org/network/903503.MEPCIT_069Putative NADH dehydrogenase subunit G; Predicted based on similarity to TIGRFAM NuoG and related proteins in nr; Belongs to the complex I 75 kDa subunit family.
nuoF protein networkhttps://string-db.org/network/903503.MEPCIT_070Putative NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit [...]
nuoE protein networkhttps://string-db.org/network/903503.MEPCIT_071Putative NADH dehydrogenase subunit E; Predicted based on similarity to TIGRFAM nuoE_fam and related proteins in nr.
nuoD protein networkhttps://string-db.org/network/903503.MEPCIT_072Putative bifunctional NADH:ubiquinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate e [...]
nuoB protein networkhttps://string-db.org/network/903503.MEPCIT_073Putative NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoA protein networkhttps://string-db.org/network/903503.MEPCIT_074Putative NADH dehydrogenase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.
mreB protein networkhttps://string-db.org/network/903503.MEPCIT_075Predicted based on similarity to TIGRFAM mreB and related proteins in nr.
mreC protein networkhttps://string-db.org/network/903503.MEPCIT_076Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
serS protein networkhttps://string-db.org/network/903503.MEPCIT_077seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
carB protein networkhttps://string-db.org/network/903503.MEPCIT_078Carbamoyl phosphate synthase large subunit; Predicted based on similarity to TIGRFAM CPSaseII_lrg and related proteins in nr; Belongs to the CarB family.
carA protein networkhttps://string-db.org/network/903503.MEPCIT_079Carbamoyl phosphate synthase small subunit; Predicted based on similarity to TIGRFAM CPSaseIIsmall and related proteins in nr; Belongs to the CarA family.
dapB protein networkhttps://string-db.org/network/903503.MEPCIT_080Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
lspA protein networkhttps://string-db.org/network/903503.MEPCIT_081Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
ileS protein networkhttps://string-db.org/network/903503.MEPCIT_082isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
rpsT protein networkhttps://string-db.org/network/903503.MEPCIT_08330S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
dnaJ protein networkhttps://string-db.org/network/903503.MEPCIT_084Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an [...]
dnaK protein networkhttps://string-db.org/network/903503.MEPCIT_085Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
sucC protein networkhttps://string-db.org/network/903503.MEPCIT_087Putative succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and [...]
sucCD protein networkhttps://string-db.org/network/903503.MEPCIT_088Putative succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and [...]
AEI74749.1 protein networkhttps://string-db.org/network/903503.MEPCIT_089Putative ATPase; Predicted based on similarity to TIGRFAM HI0065_YjeE and related proteins in nr.
mutL protein networkhttps://string-db.org/network/903503.MEPCIT_090Putative DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecul [...]
miaA protein networkhttps://string-db.org/network/903503.MEPCIT_091tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to th [...]
hfq protein networkhttps://string-db.org/network/903503.MEPCIT_092RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and chang [...]
hflK protein networkhttps://string-db.org/network/903503.MEPCIT_093FtsH protease regulator HflK; HflC and HflK could encode or regulate a protease.
hflC protein networkhttps://string-db.org/network/903503.MEPCIT_094FtsH protease regulator HflC; HflC and HflK could regulate a protease.
rnr protein networkhttps://string-db.org/network/903503.MEPCIT_095RNase R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily.
rlmB protein networkhttps://string-db.org/network/903503.MEPCIT_096Putative RNA methyltransferase, trmH family; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltr [...]
gpmA protein networkhttps://string-db.org/network/903503.MEPCIT_097Putative phosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
mnmG protein networkhttps://string-db.org/network/903503.MEPCIT_098Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s( [...]
AEI74759.1 protein networkhttps://string-db.org/network/903503.MEPCIT_099Putative outer membrane protein; Predicted based on similarity to related proteins in nr.
rpsF protein networkhttps://string-db.org/network/903503.MEPCIT_100Putative 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
priB protein networkhttps://string-db.org/network/903503.MEPCIT_101Putative primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
rpsR protein networkhttps://string-db.org/network/903503.MEPCIT_10230S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
rplI protein networkhttps://string-db.org/network/903503.MEPCIT_10350S ribosomal protein L9; Binds to the 23S rRNA.
pgl protein networkhttps://string-db.org/network/903503.MEPCIT_104Putative 6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.
lpxH protein networkhttps://string-db.org/network/903503.MEPCIT_106UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water [...]
ribE protein networkhttps://string-db.org/network/903503.MEPCIT_108Putative riboflavin synthase subunit alpha; Predicted based on similarity to TIGRFAM ribE and related proteins in nr.
AEI74767.1 protein networkhttps://string-db.org/network/903503.MEPCIT_109Putative 23S rRNA pseudouridylate synthase B; Predicted based on similarity to TIGRFAM TIGR00093 and related proteins in nr; Belongs to the pseudouridine synthase RsuA family.
trpE protein networkhttps://string-db.org/network/903503.MEPCIT_110Anthranilate synthase component I; Predicted based on similarity to TIGRFAM trpE_proteo and related proteins in nr.
trpG protein networkhttps://string-db.org/network/903503.MEPCIT_111Putative glutamine amidotransferase of anthranilate synthase; Predicted based on similarity to TIGRFAM trpG_papA and related proteins in nr.
trpC protein networkhttps://string-db.org/network/903503.MEPCIT_112N-(5'-phosphoribosyl)anthranilate isomerase; Predicted based on similarity to related proteins in nr; Belongs to the TrpC family.
trpB protein networkhttps://string-db.org/network/903503.MEPCIT_113Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpA protein networkhttps://string-db.org/network/903503.MEPCIT_114Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
AEI74773.1 protein networkhttps://string-db.org/network/903503.MEPCIT_115Conserved hypothetical protein; Predicted based on similarity to related proteins in nr.
pgi protein networkhttps://string-db.org/network/903503.MEPCIT_116Putative glucose-6-phosphate isomerase; Predicted based on similarity to related proteins in nr; Belongs to the GPI family.
AEI74775.1 protein networkhttps://string-db.org/network/903503.MEPCIT_117Putative modulator of DNA gyrase, PmbA/TldD family; Predicted based on similarity to PFAM PmbA_TldD and related proteins in nr.
AEI74776.1 protein networkhttps://string-db.org/network/903503.MEPCIT_118Putative peptidase, M23 family; Predicted based on similarity to PFAM Peptidase_M23 and related proteins in nr.
AEI74777.1 protein networkhttps://string-db.org/network/903503.MEPCIT_119Putative high-affinity zinc transporter periplasmic component; Predicted based on similarity to PFAM SBP_bac_9 and related proteins in nr.
znuC protein networkhttps://string-db.org/network/903503.MEPCIT_120Putative anchored repeat-type ABC transporter, ATP-binding subunit; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Be [...]
AEI74779.1 protein networkhttps://string-db.org/network/903503.MEPCIT_121Putative anchored repeat-type ABC transporter, permease subunit; Predicted based on similarity to TIGRFAM anch_rpt_perm and related proteins in nr.
ruvB protein networkhttps://string-db.org/network/903503.MEPCIT_122Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand [...]
ruvA protein networkhttps://string-db.org/network/903503.MEPCIT_123Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand [...]
ruvC protein networkhttps://string-db.org/network/903503.MEPCIT_124Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to st [...]
AEI74783.1 protein networkhttps://string-db.org/network/903503.MEPCIT_125Putative DNA-binding regulatory protein, YebC/PmpR family; Predicted based on similarity to TIGRFAM TIGR01033 and related proteins in nr.
aspS protein networkhttps://string-db.org/network/903503.MEPCIT_126aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
AEI74785.1 protein networkhttps://string-db.org/network/903503.MEPCIT_127Putative heat shock protein, Hsp20/alpha crystallin family; Predicted based on similarity to related proteins in nr; Belongs to the small heat shock protein (HSP20) family.
ibpA protein networkhttps://string-db.org/network/903503.MEPCIT_128Putative heat shock protein IbpA; Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock [...]
recB protein networkhttps://string-db.org/network/903503.MEPCIT_129Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-depe [...]
zwf protein networkhttps://string-db.org/network/903503.MEPCIT_130Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
pykF protein networkhttps://string-db.org/network/903503.MEPCIT_131Pyruvate kinase; Predicted based on similarity to TIGRFAM pyruv_kin and related proteins in nr; Belongs to the pyruvate kinase family.
holA protein networkhttps://string-db.org/network/903503.MEPCIT_133DNA polymerase III, delta subunit; Predicted based on similarity to TIGRFAM holA and related proteins in nr.
rlpB protein networkhttps://string-db.org/network/903503.MEPCIT_134Putative LPS-assembly lipoprotein RplB; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. [...]
leuS protein networkhttps://string-db.org/network/903503.MEPCIT_135leucyl-tRNA synthetase; Predicted based on similarity to TIGRFAM leuS_bact and related proteins in nr; Belongs to the class-I aminoacyl-tRNA synthetase family.
rnhA protein networkhttps://string-db.org/network/903503.MEPCIT_136Putative RNase H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
dnaQ protein networkhttps://string-db.org/network/903503.MEPCIT_137DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing func [...]
ung protein networkhttps://string-db.org/network/903503.MEPCIT_138uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
accD protein networkhttps://string-db.org/network/903503.MEPCIT_139acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and [...]
lipB protein networkhttps://string-db.org/network/903503.MEPCIT_140Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can al [...]
lipA protein networkhttps://string-db.org/network/903503.MEPCIT_141Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, there [...]
nusB protein networkhttps://string-db.org/network/903503.MEPCIT_144Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequ [...]
ribC protein networkhttps://string-db.org/network/903503.MEPCIT_145Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is [...]
AEI74801.1 protein networkhttps://string-db.org/network/903503.MEPCIT_146Putative peptidase, M23 family; Predicted based on similarity to PFAM Peptidase_M23.
mutS protein networkhttps://string-db.org/network/903503.MEPCIT_147DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase act [...]
AEI74803.1 protein networkhttps://string-db.org/network/903503.MEPCIT_148Putative hydrolase, TatD family; Predicted based on similarity to TIGRFAM TIGR00010 and related proteins in nr.
holB protein networkhttps://string-db.org/network/903503.MEPCIT_149Putative DNA polymerase III, delta prime subunit; Predicted based on similarity to TIGRFAM holB and related proteins in nr.
acpP protein networkhttps://string-db.org/network/903503.MEPCIT_150Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
fabG protein networkhttps://string-db.org/network/903503.MEPCIT_1513-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cy [...]
fabD protein networkhttps://string-db.org/network/903503.MEPCIT_152Malonyl CoA-(acyl-carrier-protein) transacylase; Predicted based on similarity to TIGRFAM fabD and related proteins in nr.
rpmF protein networkhttps://string-db.org/network/903503.MEPCIT_15450S ribosomal protein L32; Predicted based on similarity to TIGRFAM rpmF_bact and related proteins in nr; Belongs to the bacterial ribosomal protein bL32 family.
rluA protein networkhttps://string-db.org/network/903503.MEPCIT_155Putative pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
rne protein networkhttps://string-db.org/network/903503.MEPCIT_156Putative RNase E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradati [...]
AEI74811.1 protein networkhttps://string-db.org/network/903503.MEPCIT_157Putative PTS system, mannose/sorbose family, IID component; Predicted based on similarity to TIGRFAM EIID-AGA and related proteins in nr.
AEI74812.1 protein networkhttps://string-db.org/network/903503.MEPCIT_158Putative PTS system, mannose/sorbose family, IIC component; Predicted based on similarity to TIGRFAM EII-Sor and related proteins in nr.
AEI74813.1 protein networkhttps://string-db.org/network/903503.MEPCIT_159Putative PTS system, mannose/sorbose family, IIAB component; Predicted based on similarity to TIGRFAM pts-sorbose and related proteins in nr.
AEI74814.1 protein networkhttps://string-db.org/network/903503.MEPCIT_160Putative hypothetical protein MEPCIT_160; Predicted based on similarity to related proteins in nr.
dsbB protein networkhttps://string-db.org/network/903503.MEPCIT_161Putative disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
minC protein networkhttps://string-db.org/network/903503.MEPCIT_162Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments tha [...]
minD protein networkhttps://string-db.org/network/903503.MEPCIT_163Predicted based on similarity to TIGRFAM minD_bact and related proteins in nr.
minE protein networkhttps://string-db.org/network/903503.MEPCIT_164Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensu [...]
yeaZ protein networkhttps://string-db.org/network/903503.MEPCIT_165M22 O-sialoglycoprotein endopeptidase-like protein; Predicted based on similarity to TIGRFAM bact_YeaZ and related proteins in nr.
bamD protein networkhttps://string-db.org/network/903503.MEPCIT_166Putative outer membrane protein assembly complex subunit YfiO; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the ou [...]
AEI74821.1 protein networkhttps://string-db.org/network/903503.MEPCIT_167Putative low-affinity inorganic phosphate transport protein; Predicted based on similarity to related proteins in nr.
rplY protein networkhttps://string-db.org/network/903503.MEPCIT_16850S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
AEI74823.1 protein networkhttps://string-db.org/network/903503.MEPCIT_170Conserved hypothetical protein MEPCIT_170; Predicted based on similarity to related proteins in nr.
ligA protein networkhttps://string-db.org/network/903503.MEPCIT_171NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and [...]
recA protein networkhttps://string-db.org/network/903503.MEPCIT_173Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of ho [...]
alaS protein networkhttps://string-db.org/network/903503.MEPCIT_174alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
csrA protein networkhttps://string-db.org/network/903503.MEPCIT_175Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from ra [...]
asnS protein networkhttps://string-db.org/network/903503.MEPCIT_176asparaginyl-tRNA synthetase; Predicted based on similarity to TIGRFAM asnS and related proteins in nr.
serC protein networkhttps://string-db.org/network/903503.MEPCIT_177Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreoni [...]
rpsA protein networkhttps://string-db.org/network/903503.MEPCIT_17830S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
ahpC protein networkhttps://string-db.org/network/903503.MEPCIT_179Putative peroxiredoxin; Predicted based on similarity to TIGRFAM AhpC and related proteins in nr.
asd protein networkhttps://string-db.org/network/903503.MEPCIT_180Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the as [...]
AEI74833.1 protein networkhttps://string-db.org/network/903503.MEPCIT_181Putative serine protease Do; Predicted based on similarity to TIGRFAM degP_htrA_DO and related proteins in nr; Belongs to the peptidase S1C family.
AEI74834.1 protein networkhttps://string-db.org/network/903503.MEPCIT_182Putative hypothetical protein MEPCIT_182; Predicted based on similarity to related proteins in nr; Belongs to the BolA/IbaG family.
hisS protein networkhttps://string-db.org/network/903503.MEPCIT_184Putative histidyl-tRNA synthetase; Predicted based on similarity to TIGRFAM hisS and related proteins in nr.
yfgL protein networkhttps://string-db.org/network/903503.MEPCIT_185Outer membrane protein assembly complex subunit YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membr [...]
der protein networkhttps://string-db.org/network/903503.MEPCIT_18650S ribosomal subunit stability factor; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily [...]
rpoZ protein networkhttps://string-db.org/network/903503.MEPCIT_187DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and al [...]
recG protein networkhttps://string-db.org/network/903503.MEPCIT_188ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwindin [...]
AEI74840.1 protein networkhttps://string-db.org/network/903503.MEPCIT_190Putative ABC transporter ATP-binding protein YhbG; Predicted based on similarity to TIGRFAM 3a0106s01 and related proteins in nr.
lptA protein networkhttps://string-db.org/network/903503.MEPCIT_191Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. M [...]
lptC protein networkhttps://string-db.org/network/903503.MEPCIT_192Conserved hypothetical protein MEPCIT_192; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates t [...]
AEI74843.1 protein networkhttps://string-db.org/network/903503.MEPCIT_193Putative 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) a [...]
AEI74844.1 protein networkhttps://string-db.org/network/903503.MEPCIT_194Putative pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
AEI74845.1 protein networkhttps://string-db.org/network/903503.MEPCIT_195Putative dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
AEI74846.1 protein networkhttps://string-db.org/network/903503.MEPCIT_196Dihydrolipoyl dehydrogenase; Predicted based on similarity to TIGRFAM lipoamide_DH and related proteins in nr.
tusA protein networkhttps://string-db.org/network/903503.MEPCIT_197Conserved hypothetical protein MEPCIT_197; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouri [...]
cysG protein networkhttps://string-db.org/network/903503.MEPCIT_198Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catal [...]
cysH protein networkhttps://string-db.org/network/903503.MEPCIT_199Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
cysI protein networkhttps://string-db.org/network/903503.MEPCIT_200Sulfite reductase subunit beta; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosyn [...]
cysJ protein networkhttps://string-db.org/network/903503.MEPCIT_201Sulfite reductase subunit alpha; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosy [...]
eno protein networkhttps://string-db.org/network/903503.MEPCIT_202Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
polA protein networkhttps://string-db.org/network/903503.MEPCIT_203Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
dusA protein networkhttps://string-db.org/network/903503.MEPCIT_204Putative tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target [...]
glyQ protein networkhttps://string-db.org/network/903503.MEPCIT_207Putative glycyl-tRNA synthetase subunit alpha; Predicted based on similarity to TIGRFAM glyQ and related proteins in nr.
glyS protein networkhttps://string-db.org/network/903503.MEPCIT_208Putative glycyl-tRNA synthetase subunit beta; Predicted based on similarity to TIGRFAM glyS and related proteins in nr.
ybgT protein networkhttps://string-db.org/network/903503.MEPCIT_209Cyd operon protein YbgT; Predicted based on similarity to TIGRFAM cyd_oper_ybgT and related proteins in nr.
cydB protein networkhttps://string-db.org/network/903503.MEPCIT_210Cytochrome d ubiquinol oxidase subunit II; Predicted based on similarity to TIGRFAM cydB and related proteins in nr.
cydA protein networkhttps://string-db.org/network/903503.MEPCIT_211Putative cytochrome d ubiquinol oxidase subunit I; Predicted based on similarity to related proteins in nr.
AEI74860.1 protein networkhttps://string-db.org/network/903503.MEPCIT_213Conserved hypothetical protein; Predicted based on similarity to TIGRFAM TIGR00255 and related proteins in nr.
mraW protein networkhttps://string-db.org/network/903503.MEPCIT_214S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ftsL protein networkhttps://string-db.org/network/903503.MEPCIT_215Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins [...]
ftsI protein networkhttps://string-db.org/network/903503.MEPCIT_216Putative stage V sporulation protein D; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
mraY protein networkhttps://string-db.org/network/903503.MEPCIT_217phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...]
ftsW protein networkhttps://string-db.org/network/903503.MEPCIT_218Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
murG protein networkhttps://string-db.org/network/903503.MEPCIT_219Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide [...]
ftsA protein networkhttps://string-db.org/network/903503.MEPCIT_220Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
ftsZ protein networkhttps://string-db.org/network/903503.MEPCIT_221Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
lpxC protein networkhttps://string-db.org/network/903503.MEPCIT_222UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed st [...]
AEI74870.1 protein networkhttps://string-db.org/network/903503.MEPCIT_223Conserved hypothetical protein MEPCIT_223; Predicted based on similarity to related proteins in nr.
secA protein networkhttps://string-db.org/network/903503.MEPCIT_224Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to [...]
AEI74872.1 protein networkhttps://string-db.org/network/903503.MEPCIT_225Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Predicted based on similarity to TIGRFAM pyruv_ox_red and related proteins in nr.
pgk protein networkhttps://string-db.org/network/903503.MEPCIT_226Putative phosphoglycerate kinase; Predicted based on similarity to related proteins in nr; Belongs to the phosphoglycerate kinase family.
fbaA protein networkhttps://string-db.org/network/903503.MEPCIT_227Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphat [...]
yqgF protein networkhttps://string-db.org/network/903503.MEPCIT_228RNAse H-fold protein YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
rpoD protein networkhttps://string-db.org/network/903503.MEPCIT_230Putative RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor [...]
dnaG protein networkhttps://string-db.org/network/903503.MEPCIT_231Putative DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpsU protein networkhttps://string-db.org/network/903503.MEPCIT_23230S ribosomal protein S21; Predicted based on similarity to TIGRFAM S21p and related proteins in nr; Belongs to the bacterial ribosomal protein bS21 family.
tsaD protein networkhttps://string-db.org/network/903503.MEPCIT_233Putative glycoprotease, GCP family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in [...]
efp protein networkhttps://string-db.org/network/903503.MEPCIT_234Translational elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein [...]
aroD protein networkhttps://string-db.org/network/903503.MEPCIT_2353-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
AEI74882.1 protein networkhttps://string-db.org/network/903503.MEPCIT_236acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the car [...]
accC protein networkhttps://string-db.org/network/903503.MEPCIT_237acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier [...]
pheT protein networkhttps://string-db.org/network/903503.MEPCIT_238phenylalanyl-tRNA synthetase subunit beta; Predicted based on similarity to TIGRFAM pheT_bact and related proteins in nr; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 s [...]
pheS protein networkhttps://string-db.org/network/903503.MEPCIT_239phenylalanyl-tRNA synthetase subunit alpha; Predicted based on similarity to TIGRFAM pheS and related proteins in nr; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase [...]
rplT protein networkhttps://string-db.org/network/903503.MEPCIT_24050S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
rpmI protein networkhttps://string-db.org/network/903503.MEPCIT_24150S ribosomal protein L35; Predicted based on similarity to TIGRFAM rpmI_bact and related proteins in nr; Belongs to the bacterial ribosomal protein bL35 family.
infC protein networkhttps://string-db.org/network/903503.MEPCIT_242Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
thrS protein networkhttps://string-db.org/network/903503.MEPCIT_243threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor en [...]
aroE protein networkhttps://string-db.org/network/903503.MEPCIT_244Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshi [...]
nfuA protein networkhttps://string-db.org/network/903503.MEPCIT_246Putative IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/ [...]
AEI74892.1 protein networkhttps://string-db.org/network/903503.MEPCIT_247Conserved hypothetical protein MEPCIT_247; Predicted based on similarity to related proteins in nr.
rpoH protein networkhttps://string-db.org/network/903503.MEPCIT_248RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involve [...]
ftsY protein networkhttps://string-db.org/network/903503.MEPCIT_249Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the [...]
ychF protein networkhttps://string-db.org/network/903503.MEPCIT_250Translation-associated GTPase, YchF family; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
pth protein networkhttps://string-db.org/network/903503.MEPCIT_251peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
ribP protein networkhttps://string-db.org/network/903503.MEPCIT_252Putative ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from AT [...]
prfA protein networkhttps://string-db.org/network/903503.MEPCIT_253Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
prmC protein networkhttps://string-db.org/network/903503.MEPCIT_254protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally [...]
AEI74900.1 protein networkhttps://string-db.org/network/903503.MEPCIT_255Putative inositol monophosphatase; Predicted based on similarity to TIGRFAM his_9_proposed and related proteins in nr; Belongs to the inositol monophosphatase superfamily.
iscS protein networkhttps://string-db.org/network/903503.MEPCIT_256Cysteine desulfurase IscS; Predicted based on similarity to TIGRFAM IscS and related proteins in nr.
acpS-2 protein networkhttps://string-db.org/network/903503.MEPCIT_261Putative holo-[acyl-carrier-protein] synthase; Predicted based on similarity to TIGRFAM acpS and related proteins in nr.
pdxJ protein networkhttps://string-db.org/network/903503.MEPCIT_262Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amin [...]
clpB protein networkhttps://string-db.org/network/903503.MEPCIT_263ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE [...]
rluA-2 protein networkhttps://string-db.org/network/903503.MEPCIT_264Putative pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
AEI74906.1 protein networkhttps://string-db.org/network/903503.MEPCIT_265Putative PmbA/TldD family protein; Predicted based on similarity to PFAM PmbA_TldD and related proteins in nr.
rdgC protein networkhttps://string-db.org/network/903503.MEPCIT_266Putative exonuclease, RdgC type; May be involved in recombination; Belongs to the RdgC family.
holD protein networkhttps://string-db.org/network/903503.MEPCIT_267Putative DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to [...]
AEI74909.1 protein networkhttps://string-db.org/network/903503.MEPCIT_268Putative folate-binding protein YgfZ; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks [...]
lgt protein networkhttps://string-db.org/network/903503.MEPCIT_269Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
rppH protein networkhttps://string-db.org/network/903503.MEPCIT_270Putative hydrolase, NUDIX family; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state [...]
fis protein networkhttps://string-db.org/network/903503.MEPCIT_271Putative DNA-binding protein Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.
mrdA protein networkhttps://string-db.org/network/903503.MEPCIT_272Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
rodA protein networkhttps://string-db.org/network/903503.MEPCIT_273Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
prmB protein networkhttps://string-db.org/network/903503.MEPCIT_274protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine [...]
AEI74916.1 protein networkhttps://string-db.org/network/903503.MEPCIT_275Putative stringent starvation protein B; Predicted based on similarity to PFAM SspB related proteins in nr.
cysE protein networkhttps://string-db.org/network/903503.MEPCIT_276Serine O-acetyltransferase; Predicted based on similarity to TIGRFAM cysE and related proteins in nr; Belongs to the transferase hexapeptide repeat family.
AEI74918.1 protein networkhttps://string-db.org/network/903503.MEPCIT_278Putative DNA-binding transcriptional regulator; Predicted based on similarity to TIGRFAM PhoB and related proteins in nr.
tim protein networkhttps://string-db.org/network/903503.MEPCIT_279Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
pfkA protein networkhttps://string-db.org/network/903503.MEPCIT_2806-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
tktA protein networkhttps://string-db.org/network/903503.MEPCIT_281Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
AEI74922.1 protein networkhttps://string-db.org/network/903503.MEPCIT_282Conserved hypothetical protein; Predicted based on similarity to related proteins in nr.
ybeY protein networkhttps://string-db.org/network/903503.MEPCIT_283Putative metalloprotein YbeY family; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
proS protein networkhttps://string-db.org/network/903503.MEPCIT_288prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
argH protein networkhttps://string-db.org/network/903503.MEPCIT_289Argininosuccinate lyase; Predicted based on similarity to TIGRFAM argH and related proteins in nr.
AEI74926.1 protein networkhttps://string-db.org/network/903503.MEPCIT_290Putative superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
murJ protein networkhttps://string-db.org/network/903503.MEPCIT_291Putative integral membrane protein, MviN-like protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytopla [...]
argS protein networkhttps://string-db.org/network/903503.MEPCIT_292arginyl-tRNA synthetase; Predicted based on similarity to TIGRFAM argS and related proteins in nr.
topA protein networkhttps://string-db.org/network/903503.MEPCIT_293DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of [...]
AEI74930.1 protein networkhttps://string-db.org/network/903503.MEPCIT_294Conserved hypothetical protein MEPCIT_294; Predicted based on similarity to related proteins in nr.
tadA protein networkhttps://string-db.org/network/903503.MEPCIT_295Putative cytidine and deoxycytidylate deaminase zinc-binding region protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and [...]
rplU protein networkhttps://string-db.org/network/903503.MEPCIT_29650S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
rpmA protein networkhttps://string-db.org/network/903503.MEPCIT_29750S ribosomal protein L27; Predicted based on similarity to TIGRFAM L27 and related proteins in nr; Belongs to the bacterial ribosomal protein bL27 family.
cgtA protein networkhttps://string-db.org/network/903503.MEPCIT_298Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a ro [...]
greA protein networkhttps://string-db.org/network/903503.MEPCIT_299Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
rrmJ protein networkhttps://string-db.org/network/903503.MEPCIT_300Putative 23S rRNA methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
ftsH protein networkhttps://string-db.org/network/903503.MEPCIT_301Putative ATP-dependent metalloprotease HflB family; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of in [...]
secG protein networkhttps://string-db.org/network/903503.MEPCIT_302Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
nusA protein networkhttps://string-db.org/network/903503.MEPCIT_305Putative transcription elongation factor NusA; Participates in both transcription termination and antitermination.
infB protein networkhttps://string-db.org/network/903503.MEPCIT_306Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
rbfA protein networkhttps://string-db.org/network/903503.MEPCIT_307Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
truB protein networkhttps://string-db.org/network/903503.MEPCIT_308tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
rpsO protein networkhttps://string-db.org/network/903503.MEPCIT_30930S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
pnp protein networkhttps://string-db.org/network/903503.MEPCIT_310Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
priA-2 protein networkhttps://string-db.org/network/903503.MEPCIT_311Putative primosomal protein N; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
ptsH protein networkhttps://string-db.org/network/903503.MEPCIT_312Predicted based on similarity to TIGRFAM PTS_HPr_family and related proteins in nr.
ptsI protein networkhttps://string-db.org/network/903503.MEPCIT_313Putative phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carboh [...]
rplM protein networkhttps://string-db.org/network/903503.MEPCIT_31450S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
rpsI protein networkhttps://string-db.org/network/903503.MEPCIT_31530S ribosomal protein S9; Predicted based on similarity to TIGRFAM arch_S9P and related proteins in nr; Belongs to the universal ribosomal protein uS9 family.
clsA protein networkhttps://string-db.org/network/903503.MEPCIT_316Putative cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glyce [...]
rplS protein networkhttps://string-db.org/network/903503.MEPCIT_31750S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
trmD protein networkhttps://string-db.org/network/903503.MEPCIT_318tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rimM protein networkhttps://string-db.org/network/903503.MEPCIT_31916S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19 [...]
rpsP protein networkhttps://string-db.org/network/903503.MEPCIT_32030S ribosomal protein S16; Predicted based on similarity to TIGRFAM S16 and related proteins in nr; Belongs to the bacterial ribosomal protein bS16 family.
ffh protein networkhttps://string-db.org/network/903503.MEPCIT_321Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nasce [...]
AEI74956.1 protein networkhttps://string-db.org/network/903503.MEPCIT_322Putative murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
trmI protein networkhttps://string-db.org/network/903503.MEPCIT_323tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB f [...]
AEI74958.1 protein networkhttps://string-db.org/network/903503.MEPCIT_324RNA methyltransferase, RsmD family; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
fabF protein networkhttps://string-db.org/network/903503.MEPCIT_325Putative 3-oxoacyl-(acyl-carrier-protein) synthase II; Predicted based on similarity to TIGRFAM fabF and related proteins in nr; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP syntha [...]
map protein networkhttps://string-db.org/network/903503.MEPCIT_326Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and [...]
rpsB protein networkhttps://string-db.org/network/903503.MEPCIT_32730S ribosomal protein S2; Predicted based on similarity to TIGRFAM rpsB_bact and related proteins in nr; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/903503.MEPCIT_328Translational elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysi [...]
frr protein networkhttps://string-db.org/network/903503.MEPCIT_329Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
uppS protein networkhttps://string-db.org/network/903503.MEPCIT_330Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z, [...]
yaeT protein networkhttps://string-db.org/network/903503.MEPCIT_331Outer membrane protein assembly factor YaeT; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Cons [...]
AEI74966.1 protein networkhttps://string-db.org/network/903503.MEPCIT_332Putative Outer membrane protein (OmpH-like); Predicted based on similarity to PFAM OmpH and related proteins in nr; Belongs to the skp family.
lpxD protein networkhttps://string-db.org/network/903503.MEPCIT_333Putative UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is [...]
lpxA protein networkhttps://string-db.org/network/903503.MEPCIT_335acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membr [...]
lpxB protein networkhttps://string-db.org/network/903503.MEPCIT_336lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid t [...]
dnaE protein networkhttps://string-db.org/network/903503.MEPCIT_337DNA polymerase III, alpha subunit; Predicted based on similarity to TIGRFAM polc and related proteins in nr.
accA protein networkhttps://string-db.org/network/903503.MEPCIT_338acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its c [...]
gltX protein networkhttps://string-db.org/network/903503.MEPCIT_340glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
htpX protein networkhttps://string-db.org/network/903503.MEPCIT_343Putative heat shock protein HtpX; Predicted based on similarity to related proteins in nr; Belongs to the peptidase M48B family.
clpP protein networkhttps://string-db.org/network/903503.MEPCIT_344ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
clpX protein networkhttps://string-db.org/network/903503.MEPCIT_345ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence [...]
lon protein networkhttps://string-db.org/network/903503.MEPCIT_346ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for [...]
mscL protein networkhttps://string-db.org/network/903503.MEPCIT_347Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within th [...]
fmt protein networkhttps://string-db.org/network/903503.MEPCIT_348methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
def protein networkhttps://string-db.org/network/903503.MEPCIT_349Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
metG protein networkhttps://string-db.org/network/903503.MEPCIT_350methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
panC protein networkhttps://string-db.org/network/903503.MEPCIT_352Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase f [...]
panB protein networkhttps://string-db.org/network/903503.MEPCIT_3533-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to [...]
pcnB protein networkhttps://string-db.org/network/903503.MEPCIT_354Putative poly(A) polymerase I; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through [...]
dksA protein networkhttps://string-db.org/network/903503.MEPCIT_355DnaK transcriptional regulator DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation o [...]
recJ protein networkhttps://string-db.org/network/903503.MEPCIT_356ssDNA exonuclease RecJ; Predicted based on similarity to TIGRFAM recJ and related proteins in nr.
prfB protein networkhttps://string-db.org/network/903503.MEPCIT_357Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
lysS protein networkhttps://string-db.org/network/903503.MEPCIT_358lysyl-tRNA synthetase; Predicted based on similarity to TIGRFAM lysS_bact and related proteins in nr; Belongs to the class-II aminoacyl-tRNA synthetase family.
aroK protein networkhttps://string-db.org/network/903503.MEPCIT_359Putative shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
AEI74989.1 protein networkhttps://string-db.org/network/903503.MEPCIT_361Putative sulfur relay protein, TusE/DsrC/DsvC family; Part of a sulfur-relay system.
trmU protein networkhttps://string-db.org/network/903503.MEPCIT_362tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of [...]
pta protein networkhttps://string-db.org/network/903503.MEPCIT_363Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
ackA protein networkhttps://string-db.org/network/903503.MEPCIT_364Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
AEI74993.1 protein networkhttps://string-db.org/network/903503.MEPCIT_365Putative membrane-bound metal-dependent hydrolase; Predicted based on similarity to PFAM PF04307 and related proteins in nr.
AEI74994.1 protein networkhttps://string-db.org/network/903503.MEPCIT_366GTP-binding protein TypA/BipA; Predicted based on similarity to TIGRFAM TypA_BipA and related proteins in nr.
hisT protein networkhttps://string-db.org/network/903503.MEPCIT_368tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
birA protein networkhttps://string-db.org/network/903503.MEPCIT_369biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotin [...]
AEI74997.1 protein networkhttps://string-db.org/network/903503.MEPCIT_370Conserved hypothetical protein MEPCIT_370; Predicted based on similarity to related proteins in nr.
hemN protein networkhttps://string-db.org/network/903503.MEPCIT_371Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalentl [...]
queA protein networkhttps://string-db.org/network/903503.MEPCIT_372S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ [...]
tgt protein networkhttps://string-db.org/network/903503.MEPCIT_373Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in [...]
sufA protein networkhttps://string-db.org/network/903503.MEPCIT_374Putative FeS assembly scaffold SufA; Predicted based on similarity to TIGRFAM sufA_proteo and related proteins in nr; Belongs to the HesB/IscA family.
sufB protein networkhttps://string-db.org/network/903503.MEPCIT_375FeS assembly protein SufB; Predicted based on similarity to TIGRFAM sufB and related proteins in nr.
sufC protein networkhttps://string-db.org/network/903503.MEPCIT_376FeS assembly ATPase SufC; Predicted based on similarity to TIGRFAM sufC and related proteins in nr.
sufD protein networkhttps://string-db.org/network/903503.MEPCIT_377FeS assembly protein SufD; Predicted based on similarity to TIGRFAM sufD and related proteins in nr.
sufS protein networkhttps://string-db.org/network/903503.MEPCIT_378Cysteine desulfurase, SufS subfamily; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur- [...]
sufE protein networkhttps://string-db.org/network/903503.MEPCIT_379Putative cysteine desufuration protein SufE; Predicted based on similarity to TIGRFAM FeS_syn_CsdE and related proteins in nr.
gloB protein networkhttps://string-db.org/network/903503.MEPCIT_380Putative hydroxyacylglutathione hydrolase; Predicted based on similarity to TIGRFAM GSH_gloB and related proteins in nr.
lpxK protein networkhttps://string-db.org/network/903503.MEPCIT_381Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis [...]
msbA protein networkhttps://string-db.org/network/903503.MEPCIT_382Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) [...]
fabA protein networkhttps://string-db.org/network/903503.MEPCIT_383Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-de [...]
lon-2 protein networkhttps://string-db.org/network/903503.MEPCIT_384Putative ATP-dependent protease; Predicted based on similarity to TIGRFAM lon_rel and related proteins in nr.
AEI75012.1 protein networkhttps://string-db.org/network/903503.MEPCIT_385Flavodoxin FldA; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
recC protein networkhttps://string-db.org/network/903503.MEPCIT_387Exonuclease V subunit gamma; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bid [...]
rpsJ protein networkhttps://string-db.org/network/903503.MEPCIT_38830S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rplC protein networkhttps://string-db.org/network/903503.MEPCIT_38950S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplD protein networkhttps://string-db.org/network/903503.MEPCIT_390Putative 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
rplW protein networkhttps://string-db.org/network/903503.MEPCIT_391Putative 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the [...]
rplB protein networkhttps://string-db.org/network/903503.MEPCIT_39250S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rpsS protein networkhttps://string-db.org/network/903503.MEPCIT_39330S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplV protein networkhttps://string-db.org/network/903503.MEPCIT_394Putative 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that line [...]
rpsC protein networkhttps://string-db.org/network/903503.MEPCIT_39530S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplP protein networkhttps://string-db.org/network/903503.MEPCIT_39650S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpmC protein networkhttps://string-db.org/network/903503.MEPCIT_397Putative ribosomal protein L29; Predicted based on similarity to TIGRFAM L29 and related proteins in nr; Belongs to the universal ribosomal protein uL29 family.
rpsQ protein networkhttps://string-db.org/network/903503.MEPCIT_398Putative 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rplN protein networkhttps://string-db.org/network/903503.MEPCIT_399Putative 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rplX protein networkhttps://string-db.org/network/903503.MEPCIT_40050S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplE protein networkhttps://string-db.org/network/903503.MEPCIT_401Putative ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protube [...]
rpsN protein networkhttps://string-db.org/network/903503.MEPCIT_402Putative ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to t [...]
rpsH protein networkhttps://string-db.org/network/903503.MEPCIT_403Putative 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Be [...]
rplF protein networkhttps://string-db.org/network/903503.MEPCIT_404Putative 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and n [...]
rplR protein networkhttps://string-db.org/network/903503.MEPCIT_40550S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
rpsE protein networkhttps://string-db.org/network/903503.MEPCIT_40630S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 fam [...]
rpmD protein networkhttps://string-db.org/network/903503.MEPCIT_40750S ribosomal protein L30; Predicted based on similarity to TIGRFAM rpmD_bact and related proteins in nr.
rplO protein networkhttps://string-db.org/network/903503.MEPCIT_40850S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
secY protein networkhttps://string-db.org/network/903503.MEPCIT_409Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at t [...]
rpmJ protein networkhttps://string-db.org/network/903503.MEPCIT_41050S ribosomal protein L36; Predicted based on similarity to TIGRFAM rpmJ_bact and related proteins in nr; Belongs to the bacterial ribosomal protein bL36 family.
rpsM protein networkhttps://string-db.org/network/903503.MEPCIT_41130S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpsK protein networkhttps://string-db.org/network/903503.MEPCIT_41230S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsD protein networkhttps://string-db.org/network/903503.MEPCIT_41330S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpoA protein networkhttps://string-db.org/network/903503.MEPCIT_414DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplQ protein networkhttps://string-db.org/network/903503.MEPCIT_41550S ribosomal protein L17; Predicted based on similarity to TIGRFAM L17 and related proteins in nr.
groL protein networkhttps://string-db.org/network/903503.MEPCIT_416Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
groS protein networkhttps://string-db.org/network/903503.MEPCIT_417Putative co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
grpE protein networkhttps://string-db.org/network/903503.MEPCIT_418Putative heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and Grp [...]
smpB protein networkhttps://string-db.org/network/903503.MEPCIT_419SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
glnS protein networkhttps://string-db.org/network/903503.MEPCIT_420glutaminyl-tRNA synthetase; Predicted based on similarity to TIGRFAM glnS and related proteins in nr.
orn protein networkhttps://string-db.org/network/903503.MEPCIT_421Putative exonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
erpA protein networkhttps://string-db.org/network/903503.MEPCIT_422Putative iron-sulfur cluster assembly accessory protein; Required for insertion of 4Fe-4S clusters for at least IspG.
xthA protein networkhttps://string-db.org/network/903503.MEPCIT_424Exonuclease III; Predicted based on similarity to TIGRFAM exoDNase_III and related proteins in nr.
tyrS protein networkhttps://string-db.org/network/903503.MEPCIT_425tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
thiE protein networkhttps://string-db.org/network/903503.MEPCIT_429Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamin [...]
rpoC protein networkhttps://string-db.org/network/903503.MEPCIT_430DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/903503.MEPCIT_431DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/903503.MEPCIT_43250S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the ba [...]
rplJ protein networkhttps://string-db.org/network/903503.MEPCIT_433Putative 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribos [...]
rplA protein networkhttps://string-db.org/network/903503.MEPCIT_43450S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/903503.MEPCIT_43550S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/903503.MEPCIT_436Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the [...]
secE protein networkhttps://string-db.org/network/903503.MEPCIT_437Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; B [...]
tufA protein networkhttps://string-db.org/network/903503.MEPCIT_438Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
AEI75061.1 protein networkhttps://string-db.org/network/903503.MEPCIT_443Putative permease, YjgP/YjgQ family; Predicted based on similarity to PFAM YjgP_YjgQ and related proteins in nr.
AEI75062.1 protein networkhttps://string-db.org/network/903503.MEPCIT_444Putative permease, YjgP/YjgQ family; Predicted based on similarity to PFAM YjgP_YjgQ and related proteins in nr.
holC protein networkhttps://string-db.org/network/903503.MEPCIT_445Putative DNA polymerase III subunit chi; Predicted based on similarity to related proteins in nr.
valS protein networkhttps://string-db.org/network/903503.MEPCIT_446valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
argF protein networkhttps://string-db.org/network/903503.MEPCIT_447Ornithine carbamoyltransferase subunit I; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; [...]
nrdB protein networkhttps://string-db.org/network/903503.MEPCIT_448Putative ribonucleotide-diphosphate reductase subunit beta; Predicted based on similarity to related proteins in nr.
nrdA protein networkhttps://string-db.org/network/903503.MEPCIT_449Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
gyrA protein networkhttps://string-db.org/network/903503.MEPCIT_450DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
AEI75069.1 protein networkhttps://string-db.org/network/903503.MEPCIT_451Putative thioredoxin reductase; Predicted based on similarity to TIGRFAM TRX_reduct and related proteins in nr.
cydD protein networkhttps://string-db.org/network/903503.MEPCIT_452Thiol reductant ABC exporter, CydD subunit; Predicted based on similarity to TIGRFAM CydD and related proteins in nr.
cydC protein networkhttps://string-db.org/network/903503.MEPCIT_453Thiol reductant ABC exporter, CydC subunit; Predicted based on similarity to TIGRFAM CydC and related proteins in nr.
infA protein networkhttps://string-db.org/network/903503.MEPCIT_454Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
fusA protein networkhttps://string-db.org/network/903503.MEPCIT_455Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) [...]
rpsG protein networkhttps://string-db.org/network/903503.MEPCIT_45630S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
rpsL protein networkhttps://string-db.org/network/903503.MEPCIT_45730S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S an [...]
tusB protein networkhttps://string-db.org/network/903503.MEPCIT_458Putative sulfur relay protein TusB/DsrH; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
tusC protein networkhttps://string-db.org/network/903503.MEPCIT_459Sulfur relay protein TusC/DsrF; Predicted based on similarity to TIGRFAM sulf_tusC_dsrF and related proteins in nr; Belongs to the DsrF/TusC family.
tusD protein networkhttps://string-db.org/network/903503.MEPCIT_460Sulfur relay protein TusD/DsrE; Predicted based on similarity to TIGRFAM sulf_tusD_dsrE and related proteins in nr.
tilS protein networkhttps://string-db.org/network/903503.MEPCIT_461Putative tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cy [...]
AEI75080.1 protein networkhttps://string-db.org/network/903503.MEPCIT_462Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domai [...]