Organism Overview: Ishikawaella capsulata


 
gidA protein networkhttps://string-db.org/network/476281.ICMP_001Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s( [...]
atpB protein networkhttps://string-db.org/network/476281.ICMP_002F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.
atpE protein networkhttps://string-db.org/network/476281.ICMP_003F0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extr [...]
atpF protein networkhttps://string-db.org/network/476281.ICMP_004F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
atpH protein networkhttps://string-db.org/network/476281.ICMP_005F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the [...]
atpA protein networkhttps://string-db.org/network/476281.ICMP_006F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
atpG protein networkhttps://string-db.org/network/476281.ICMP_007F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the [...]
atpD protein networkhttps://string-db.org/network/476281.ICMP_008F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
atpC protein networkhttps://string-db.org/network/476281.ICMP_009F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.
trmE protein networkhttps://string-db.org/network/476281.ICMP_010tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, [...]
yidC protein networkhttps://string-db.org/network/476281.ICMP_011Inner membrane protein translocase component; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of [...]
yidD protein networkhttps://string-db.org/network/476281.ICMP_012Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
rnpA protein networkhttps://string-db.org/network/476281.ICMP_013Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein compo [...]
rpmH protein networkhttps://string-db.org/network/476281.ICMP_01450S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
dnaA protein networkhttps://string-db.org/network/476281.ICMP_015Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-s [...]
dnaN protein networkhttps://string-db.org/network/476281.ICMP_016DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadin [...]
gyrB protein networkhttps://string-db.org/network/476281.ICMP_017DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
dnaT protein networkhttps://string-db.org/network/476281.ICMP_018Primosomal protein I.
dnaC protein networkhttps://string-db.org/network/476281.ICMP_019DNA biosynthesis protein.
glyQ protein networkhttps://string-db.org/network/476281.ICMP_020glycyl-tRNA synthetase subunit alpha.
glyS protein networkhttps://string-db.org/network/476281.ICMP_021glycyl-tRNA synthetase subunit beta.
fdhD protein networkhttps://string-db.org/network/476281.ICMP_022Formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to it [...]
sodA protein networkhttps://string-db.org/network/476281.ICMP_023Superoxide dismutase(Mn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
argE protein networkhttps://string-db.org/network/476281.ICMP_024Acetylornithine deacetylase.
argC protein networkhttps://string-db.org/network/476281.ICMP_025N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydroge [...]
argB protein networkhttps://string-db.org/network/476281.ICMP_026Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate.
argG protein networkhttps://string-db.org/network/476281.ICMP_027Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
argH protein networkhttps://string-db.org/network/476281.ICMP_028Argininosuccinate lyase.
ilvD protein networkhttps://string-db.org/network/476281.ICMP_036Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
ilvA protein networkhttps://string-db.org/network/476281.ICMP_037Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a producti [...]
ilvC protein networkhttps://string-db.org/network/476281.ICMP_038Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
sgaU protein networkhttps://string-db.org/network/476281.ICMP_039L-xylulose 5-phosphate 3-epimerase like protein.
prlC protein networkhttps://string-db.org/network/476281.ICMP_040Oligopeptidase A.
yhiQ protein networkhttps://string-db.org/network/476281.ICMP_041Predicted SAM-dependent methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA.
accD protein networkhttps://string-db.org/network/476281.ICMP_042acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and [...]
folC protein networkhttps://string-db.org/network/476281.ICMP_043Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to [...]
cvpA protein networkhttps://string-db.org/network/476281.ICMP_044Membrane protein required for colicin V production.
ubiX protein networkhttps://string-db.org/network/476281.ICMP_0453-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylas [...]
pta protein networkhttps://string-db.org/network/476281.ICMP_046Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
ackA protein networkhttps://string-db.org/network/476281.ICMP_047Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
nuoA protein networkhttps://string-db.org/network/476281.ICMP_048NADH:ubiquinone oxidoreductase chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the e [...]
nuoB protein networkhttps://string-db.org/network/476281.ICMP_049NADH:ubiquinone oxidoreductase chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the e [...]
nuoC protein networkhttps://string-db.org/network/476281.ICMP_050NADH:ubiquinone oxidoreductase chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the [...]
nuoE protein networkhttps://string-db.org/network/476281.ICMP_051NADH:ubiquinone oxidoreductase chain E.
nuoF protein networkhttps://string-db.org/network/476281.ICMP_052NADH:ubiquinone oxidoreductase chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit f [...]
nuoG protein networkhttps://string-db.org/network/476281.ICMP_053NADH:ubiquinone oxidoreductase chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton tran [...]
nuoH protein networkhttps://string-db.org/network/476281.ICMP_054NADH:ubiquinone oxidoreductase chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the e [...]
nuoI protein networkhttps://string-db.org/network/476281.ICMP_055NADH:ubiquinone oxidoreductase chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the e [...]
nuoJ protein networkhttps://string-db.org/network/476281.ICMP_056NADH:ubiquinone oxidoreductase chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton tran [...]
nuoK protein networkhttps://string-db.org/network/476281.ICMP_057NADH:ubiquinone oxidoreductase chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the e [...]
nuoL protein networkhttps://string-db.org/network/476281.ICMP_058NADH:ubiquinone oxidoreductase chain L.
nuoM protein networkhttps://string-db.org/network/476281.ICMP_059NADH:ubiquinone oxidoreductase chain M.
nuoN protein networkhttps://string-db.org/network/476281.ICMP_060NADH:ubiquinone oxidoreductase chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the e [...]
elaB protein networkhttps://string-db.org/network/476281.ICMP_061Hypothetical protein.
yfaE protein networkhttps://string-db.org/network/476281.ICMP_062Predicted 2Fe-2S cluster-containing protein.
nrdB protein networkhttps://string-db.org/network/476281.ICMP_063Ribonucleotide-diphosphate reductase beta subunit.
nrdA protein networkhttps://string-db.org/network/476281.ICMP_064Ribonucleotide-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
gyrA protein networkhttps://string-db.org/network/476281.ICMP_065DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
serS protein networkhttps://string-db.org/network/476281.ICMP_066seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
ICMP_067 protein networkhttps://string-db.org/network/476281.ICMP_067Phospholipid N-methyltransferase.
suhB protein networkhttps://string-db.org/network/476281.ICMP_068Inositol monophosphatase.
iscS protein networkhttps://string-db.org/network/476281.ICMP_069Cysteine desulfurase.
ndk protein networkhttps://string-db.org/network/476281.ICMP_070Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, [...]
yfgB protein networkhttps://string-db.org/network/476281.ICMP_071Predicted enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step [...]
hisS protein networkhttps://string-db.org/network/476281.ICMP_072histidyl-tRNA synthetase.
yfgM protein networkhttps://string-db.org/network/476281.ICMP_073Hypothetical protein.
yfgL protein networkhttps://string-db.org/network/476281.ICMP_074Hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
der protein networkhttps://string-db.org/network/476281.ICMP_075GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) G [...]
guaB protein networkhttps://string-db.org/network/476281.ICMP_076Inositol-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesi [...]
guaA protein networkhttps://string-db.org/network/476281.ICMP_077Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
bcp protein networkhttps://string-db.org/network/476281.ICMP_078Thioredoxin-dependent thiol peroxidase.
dapA protein networkhttps://string-db.org/network/476281.ICMP_079Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
nlpB protein networkhttps://string-db.org/network/476281.ICMP_080Lipoprotein.
dapE protein networkhttps://string-db.org/network/476281.ICMP_081Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in [...]
ydjM protein networkhttps://string-db.org/network/476281.ICMP_082Predicted inner membrane protein regulated by LexA.
fabI protein networkhttps://string-db.org/network/476281.ICMP_083Enoyl-(acyl carrier protein) reductase.
rnb protein networkhttps://string-db.org/network/476281.ICMP_084Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
pyrF protein networkhttps://string-db.org/network/476281.ICMP_085Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamil [...]
pgpB protein networkhttps://string-db.org/network/476281.ICMP_086Phosphatidylglycerophosphatase B.
ribA protein networkhttps://string-db.org/network/476281.ICMP_087GTP cyclohydrolase II protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
acnA protein networkhttps://string-db.org/network/476281.ICMP_088Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
cysB protein networkhttps://string-db.org/network/476281.ICMP_089DNA-binding transcriptional dual regulator, O-acetyl-L-serine-binding; Belongs to the LysR transcriptional regulatory family.
sohB protein networkhttps://string-db.org/network/476281.ICMP_090Predicted inner membrane peptidase.
trpE protein networkhttps://string-db.org/network/476281.ICMP_091Anthranilate synthase component I.
trpD_1 protein networkhttps://string-db.org/network/476281.ICMP_092Bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase.
trpD_2 protein networkhttps://string-db.org/network/476281.ICMP_093Bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthr [...]
trpC protein networkhttps://string-db.org/network/476281.ICMP_094Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Belongs to the TrpC family.
trpB protein networkhttps://string-db.org/network/476281.ICMP_095Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpA protein networkhttps://string-db.org/network/476281.ICMP_096Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
truA protein networkhttps://string-db.org/network/476281.ICMP_097tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
pdxB protein networkhttps://string-db.org/network/476281.ICMP_098Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
fabB protein networkhttps://string-db.org/network/476281.ICMP_0993-oxoacyl-(acyl carrier protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
aroC protein networkhttps://string-db.org/network/476281.ICMP_100Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
prmB protein networkhttps://string-db.org/network/476281.ICMP_101N5-glutamine methyltransferase; Belongs to the protein N5-glutamine methyltransferase family.
ubiD protein networkhttps://string-db.org/network/476281.ICMP_1043-octaprenyl-4-hydroxybenzoate decarboxylase; Belongs to the UbiD family.
glk protein networkhttps://string-db.org/network/476281.ICMP_105Glucokinase; Belongs to the bacterial glucokinase family.
gltX protein networkhttps://string-db.org/network/476281.ICMP_107glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
ligA protein networkhttps://string-db.org/network/476281.ICMP_111NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and [...]
cysK protein networkhttps://string-db.org/network/476281.ICMP_112Cysteine synthase A, O-acetylserine sulfhydrolase A subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
ppa protein networkhttps://string-db.org/network/476281.ICMP_113Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
bioH protein networkhttps://string-db.org/network/476281.ICMP_114Carboxylesterase of pimeloyl-CoA synthesis; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl- [...]
gntY protein networkhttps://string-db.org/network/476281.ICMP_115Predicted gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the matur [...]
thyA protein networkhttps://string-db.org/network/476281.ICMP_116Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...]
lgt protein networkhttps://string-db.org/network/476281.ICMP_117Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
mutH protein networkhttps://string-db.org/network/476281.ICMP_118DNA mismatch repair protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.
ygdQ protein networkhttps://string-db.org/network/476281.ICMP_119Predicted inner membrane protein.
mutS protein networkhttps://string-db.org/network/476281.ICMP_120DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity [...]
rpoS protein networkhttps://string-db.org/network/476281.ICMP_121RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master [...]
ftsB protein networkhttps://string-db.org/network/476281.ICMP_122Cell divison protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, [...]
cysC protein networkhttps://string-db.org/network/476281.ICMP_123Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
cysN protein networkhttps://string-db.org/network/476281.ICMP_124Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase [...]
cysD protein networkhttps://string-db.org/network/476281.ICMP_125Sulfate adenylyltransferase subunit 2.
cysG protein networkhttps://string-db.org/network/476281.ICMP_126Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. [...]
cysH protein networkhttps://string-db.org/network/476281.ICMP_127Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
cysI protein networkhttps://string-db.org/network/476281.ICMP_128Sulfite reductase beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosyn [...]
cysJ protein networkhttps://string-db.org/network/476281.ICMP_129Sulfite reductase alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosy [...]
eno protein networkhttps://string-db.org/network/476281.ICMP_130Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
pyrG protein networkhttps://string-db.org/network/476281.ICMP_131CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the [...]
argA protein networkhttps://string-db.org/network/476281.ICMP_133N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily.
recD protein networkhttps://string-db.org/network/476281.ICMP_134RecBCD complex alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidi [...]
recB protein networkhttps://string-db.org/network/476281.ICMP_135RecBCD complex beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bid [...]
recC protein networkhttps://string-db.org/network/476281.ICMP_136RecBCD complex gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidi [...]
asd protein networkhttps://string-db.org/network/476281.ICMP_137Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the as [...]
yhgN protein networkhttps://string-db.org/network/476281.ICMP_138Predicted antibiotic transporter.
rpoH protein networkhttps://string-db.org/network/476281.ICMP_139RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved i [...]
ftsY protein networkhttps://string-db.org/network/476281.ICMP_140Fused signal recognition particle receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal [...]
yhhF protein networkhttps://string-db.org/network/476281.ICMP_141Predicted methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
yhhP protein networkhttps://string-db.org/network/476281.ICMP_142Cell developmental protein SirA; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of th [...]
ygfZ protein networkhttps://string-db.org/network/476281.ICMP_143Putative global regulator; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act v [...]
ygfY protein networkhttps://string-db.org/network/476281.ICMP_144TFIIB like protein.
ICMP_145 protein networkhttps://string-db.org/network/476281.ICMP_145Hypothetical protein.
ICMP_146 protein networkhttps://string-db.org/network/476281.ICMP_146Hypothetical protein.
prfB protein networkhttps://string-db.org/network/476281.ICMP_147Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
lysS protein networkhttps://string-db.org/network/476281.ICMP_148Lysine tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
lysA protein networkhttps://string-db.org/network/476281.ICMP_149Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
ygfA protein networkhttps://string-db.org/network/476281.ICMP_150Predicted ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
rpiA protein networkhttps://string-db.org/network/476281.ICMP_151Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
fbaA protein networkhttps://string-db.org/network/476281.ICMP_152Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphat [...]
pgk protein networkhttps://string-db.org/network/476281.ICMP_153Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
tktA protein networkhttps://string-db.org/network/476281.ICMP_154Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
obgE protein networkhttps://string-db.org/network/476281.ICMP_155GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of [...]
rpmA protein networkhttps://string-db.org/network/476281.ICMP_15650S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
rplU protein networkhttps://string-db.org/network/476281.ICMP_15750S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
murA protein networkhttps://string-db.org/network/476281.ICMP_158UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
yrbA protein networkhttps://string-db.org/network/476281.ICMP_159Predicted DNA-binding transcriptional regulator; Belongs to the BolA/IbaG family.
sspB protein networkhttps://string-db.org/network/476281.ICMP_160ClpXP protease specificity-enhancing factor.
rpsI protein networkhttps://string-db.org/network/476281.ICMP_16130S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
rplM protein networkhttps://string-db.org/network/476281.ICMP_16250S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
yhcM protein networkhttps://string-db.org/network/476281.ICMP_163Conserved protein with nucleoside triphosphate hydrolase domain.
poxA protein networkhttps://string-db.org/network/476281.ICMP_164Hypothetical protein.
efp protein networkhttps://string-db.org/network/476281.ICMP_165Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by [...]
yjeK protein networkhttps://string-db.org/network/476281.ICMP_166Lysine 2,3-aminomutase.
groL protein networkhttps://string-db.org/network/476281.ICMP_167Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
groS protein networkhttps://string-db.org/network/476281.ICMP_168Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
cysQ protein networkhttps://string-db.org/network/476281.ICMP_169PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ [...]
rplI protein networkhttps://string-db.org/network/476281.ICMP_17050S ribosomal protein L9; Binds to the 23S rRNA.
rpsR protein networkhttps://string-db.org/network/476281.ICMP_17130S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
rpsF protein networkhttps://string-db.org/network/476281.ICMP_17230S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
rlmB protein networkhttps://string-db.org/network/476281.ICMP_17323S rRNA (Gm2251)-methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
rnr protein networkhttps://string-db.org/network/476281.ICMP_174Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily.
purA protein networkhttps://string-db.org/network/476281.ICMP_175Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
hflX protein networkhttps://string-db.org/network/476281.ICMP_176Predicted GTPase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase super [...]
miaA protein networkhttps://string-db.org/network/476281.ICMP_177tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to th [...]
mutL protein networkhttps://string-db.org/network/476281.ICMP_178DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker' [...]
amiB protein networkhttps://string-db.org/network/476281.ICMP_179N-acetylmuramoyl-l-alanine amidase II.
yjeF protein networkhttps://string-db.org/network/476281.ICMP_180Predicted carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is [...]
orn protein networkhttps://string-db.org/network/476281.ICMP_182Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
yjeP protein networkhttps://string-db.org/network/476281.ICMP_183Predicted mechanosensitive channel.
mdh protein networkhttps://string-db.org/network/476281.ICMP_184Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
tldD protein networkhttps://string-db.org/network/476281.ICMP_185Predicted peptidase.
mreD protein networkhttps://string-db.org/network/476281.ICMP_186Cell wall structural complex MreBCD; Transmembrane component MreD.
mreC protein networkhttps://string-db.org/network/476281.ICMP_187Cell wall structural complex MreBCD; Involved in formation and maintenance of cell shape.
mreB protein networkhttps://string-db.org/network/476281.ICMP_188Cell wall structural complex MreBCD, actin-like component MreB.
aroD protein networkhttps://string-db.org/network/476281.ICMP_1893-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
accB protein networkhttps://string-db.org/network/476281.ICMP_190acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transca [...]
accC protein networkhttps://string-db.org/network/476281.ICMP_191acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transca [...]
proS protein networkhttps://string-db.org/network/476281.ICMP_192prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
tilS protein networkhttps://string-db.org/network/476281.ICMP_193tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is [...]
accA protein networkhttps://string-db.org/network/476281.ICMP_194acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) a [...]
dnaE protein networkhttps://string-db.org/network/476281.ICMP_195DNA polymerase III subunit alpha.
rnhB protein networkhttps://string-db.org/network/476281.ICMP_196Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
fabZ protein networkhttps://string-db.org/network/476281.ICMP_197(3R)-hydroxymyristoyl ACP dehydratase.
fabZ-2 protein networkhttps://string-db.org/network/476281.ICMP_198(3R)-hydroxymyristoyl ACP dehydratase.
yaeT protein networkhttps://string-db.org/network/476281.ICMP_199Hypothetical protein.
yaeL protein networkhttps://string-db.org/network/476281.ICMP_200Zinc metallopeptidase.
ispU protein networkhttps://string-db.org/network/476281.ICMP_201Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E [...]
frr protein networkhttps://string-db.org/network/476281.ICMP_202Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
pyrH protein networkhttps://string-db.org/network/476281.ICMP_203Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
tsf protein networkhttps://string-db.org/network/476281.ICMP_204Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
rpsB protein networkhttps://string-db.org/network/476281.ICMP_20530S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
dapD protein networkhttps://string-db.org/network/476281.ICMP_2062,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
pfs protein networkhttps://string-db.org/network/476281.ICMP_2075'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) [...]
yadR protein networkhttps://string-db.org/network/476281.ICMP_208Hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG.
dksA protein networkhttps://string-db.org/network/476281.ICMP_209DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several am [...]
pcnB protein networkhttps://string-db.org/network/476281.ICMP_210poly(A) polymerase I; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influenc [...]
folK protein networkhttps://string-db.org/network/476281.ICMP_2112-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase.
panB protein networkhttps://string-db.org/network/476281.ICMP_2123-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to [...]
panC protein networkhttps://string-db.org/network/476281.ICMP_213Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase fa [...]
xthA protein networkhttps://string-db.org/network/476281.ICMP_214Exonuclease III.
ICMP_215 protein networkhttps://string-db.org/network/476281.ICMP_215Hypothetical protein; N-terminal transmembrane region have sequence similarity to sppA.
yadH protein networkhttps://string-db.org/network/476281.ICMP_216Predicted transporter subunit: membrane component of ABC superfamily.
yadG protein networkhttps://string-db.org/network/476281.ICMP_217Predicted transporter subunit: ATP-binding component of ABC superfamily.
hpt protein networkhttps://string-db.org/network/476281.ICMP_218Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
sppA protein networkhttps://string-db.org/network/476281.ICMP_219Protease IV.
gapA protein networkhttps://string-db.org/network/476281.ICMP_220Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
minC protein networkhttps://string-db.org/network/476281.ICMP_221Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have for [...]
minD protein networkhttps://string-db.org/network/476281.ICMP_222Membrane ATPase of the MinC-MinD-MinE system.
minE protein networkhttps://string-db.org/network/476281.ICMP_223Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensu [...]
yeaZ protein networkhttps://string-db.org/network/476281.ICMP_224Predicted peptidase.
pabB protein networkhttps://string-db.org/network/476281.ICMP_225Para-aminobenzoate synthase component I.
htpX protein networkhttps://string-db.org/network/476281.ICMP_226Heat shock protein HtpX.
zwf protein networkhttps://string-db.org/network/476281.ICMP_227Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
ruvB protein networkhttps://string-db.org/network/476281.ICMP_228Holliday junction DNA helicase B; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand ex [...]
ruvA protein networkhttps://string-db.org/network/476281.ICMP_229Holliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promo [...]
folD protein networkhttps://string-db.org/network/476281.ICMP_231Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10 [...]
cysS protein networkhttps://string-db.org/network/476281.ICMP_232cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
cls protein networkhttps://string-db.org/network/476281.ICMP_234Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
tgt protein networkhttps://string-db.org/network/476281.ICMP_235Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in [...]
secD protein networkhttps://string-db.org/network/476281.ICMP_236Protein export protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein tra [...]
secF protein networkhttps://string-db.org/network/476281.ICMP_237Protein export protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein tra [...]
ribD protein networkhttps://string-db.org/network/476281.ICMP_238Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphat [...]
ribE protein networkhttps://string-db.org/network/476281.ICMP_239Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is [...]
nusB protein networkhttps://string-db.org/network/476281.ICMP_240Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequ [...]
phr protein networkhttps://string-db.org/network/476281.ICMP_241Deoxyribodipyrimidine photolyase, FAD-binding; Belongs to the DNA photolyase family.
tsgA protein networkhttps://string-db.org/network/476281.ICMP_242Hypothetical protein.
pabA protein networkhttps://string-db.org/network/476281.ICMP_243Para-aminobenzoate synthase component II.
yheN protein networkhttps://string-db.org/network/476281.ICMP_244Hypothetical protein tusD.
yheM protein networkhttps://string-db.org/network/476281.ICMP_245Hypothetical protein tusC; Belongs to the DsrF/TusC family.
yheL protein networkhttps://string-db.org/network/476281.ICMP_246Predicted intracellular sulfur oxidation protein tusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
rpsL protein networkhttps://string-db.org/network/476281.ICMP_24730S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S an [...]
rpsG protein networkhttps://string-db.org/network/476281.ICMP_24830S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
fusA protein networkhttps://string-db.org/network/476281.ICMP_249Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the po [...]
tufB protein networkhttps://string-db.org/network/476281.ICMP_250Protein chain elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
rpsJ protein networkhttps://string-db.org/network/476281.ICMP_25130S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rplC protein networkhttps://string-db.org/network/476281.ICMP_25250S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplD protein networkhttps://string-db.org/network/476281.ICMP_25350S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
rplW protein networkhttps://string-db.org/network/476281.ICMP_25450S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplB protein networkhttps://string-db.org/network/476281.ICMP_25550S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rpsS protein networkhttps://string-db.org/network/476281.ICMP_25630S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplV protein networkhttps://string-db.org/network/476281.ICMP_25750S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wal [...]
rpsC protein networkhttps://string-db.org/network/476281.ICMP_25830S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplP protein networkhttps://string-db.org/network/476281.ICMP_25950S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpmC protein networkhttps://string-db.org/network/476281.ICMP_26050S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
rpsQ protein networkhttps://string-db.org/network/476281.ICMP_26130S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rplN protein networkhttps://string-db.org/network/476281.ICMP_26250S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rplX protein networkhttps://string-db.org/network/476281.ICMP_26350S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplE protein networkhttps://string-db.org/network/476281.ICMP_26450S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rpsN protein networkhttps://string-db.org/network/476281.ICMP_26530S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the un [...]
rpsH protein networkhttps://string-db.org/network/476281.ICMP_26630S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to [...]
rplF protein networkhttps://string-db.org/network/476281.ICMP_26750S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rplR protein networkhttps://string-db.org/network/476281.ICMP_26850S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
rpsE protein networkhttps://string-db.org/network/476281.ICMP_26930S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 fam [...]
rpmD protein networkhttps://string-db.org/network/476281.ICMP_27050S ribosomal protein L30.
rplO protein networkhttps://string-db.org/network/476281.ICMP_27150S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
secY protein networkhttps://string-db.org/network/476281.ICMP_272Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the [...]
rpmJ protein networkhttps://string-db.org/network/476281.ICMP_27350S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
rpsM protein networkhttps://string-db.org/network/476281.ICMP_27430S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpsK protein networkhttps://string-db.org/network/476281.ICMP_27530S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsD protein networkhttps://string-db.org/network/476281.ICMP_27630S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpoA protein networkhttps://string-db.org/network/476281.ICMP_277DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplQ protein networkhttps://string-db.org/network/476281.ICMP_27850S ribosomal protein L17.
fmt protein networkhttps://string-db.org/network/476281.ICMP_279methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
def protein networkhttps://string-db.org/network/476281.ICMP_280Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
aroE protein networkhttps://string-db.org/network/476281.ICMP_281Dehydroshikimate reductase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydrosh [...]
greA protein networkhttps://string-db.org/network/476281.ICMP_285Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
rrmJ protein networkhttps://string-db.org/network/476281.ICMP_28623S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
ftsH protein networkhttps://string-db.org/network/476281.ICMP_287Protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the A [...]
folP protein networkhttps://string-db.org/network/476281.ICMP_2887,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immedi [...]
secG protein networkhttps://string-db.org/network/476281.ICMP_289Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
nusA protein networkhttps://string-db.org/network/476281.ICMP_291Transcription elongation factor NusA; Participates in both transcription termination and antitermination.
infB protein networkhttps://string-db.org/network/476281.ICMP_292Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
rbfA protein networkhttps://string-db.org/network/476281.ICMP_293Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
truB protein networkhttps://string-db.org/network/476281.ICMP_294tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
rpsO protein networkhttps://string-db.org/network/476281.ICMP_29530S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
pnp protein networkhttps://string-db.org/network/476281.ICMP_296Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
deaD protein networkhttps://string-db.org/network/476281.ICMP_297ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
valS protein networkhttps://string-db.org/network/476281.ICMP_298valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
pepA protein networkhttps://string-db.org/network/476281.ICMP_299Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
argI protein networkhttps://string-db.org/network/476281.ICMP_300Ornithine carbamoyltransferase 1; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
pyrB protein networkhttps://string-db.org/network/476281.ICMP_301Aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
pyrI protein networkhttps://string-db.org/network/476281.ICMP_302Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
yjgF protein networkhttps://string-db.org/network/476281.ICMP_303Ketoacid-binding protein.
rimI protein networkhttps://string-db.org/network/476281.ICMP_305Ribosomal-protein-alanine N-acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.
radA protein networkhttps://string-db.org/network/476281.ICMP_306Predicted repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand [...]
thrA protein networkhttps://string-db.org/network/476281.ICMP_307Bifunctional aspartokinase I/homeserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family.
thrB protein networkhttps://string-db.org/network/476281.ICMP_308Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
thrC protein networkhttps://string-db.org/network/476281.ICMP_309Threonine synthase.
talB protein networkhttps://string-db.org/network/476281.ICMP_310Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
mog protein networkhttps://string-db.org/network/476281.ICMP_311Molybdenum cofactor biosynthesis protein.
dnaK protein networkhttps://string-db.org/network/476281.ICMP_312Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
dnaJ protein networkhttps://string-db.org/network/476281.ICMP_313Chaperone Hsp40; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonom [...]
rpsT protein networkhttps://string-db.org/network/476281.ICMP_31430S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
ileS protein networkhttps://string-db.org/network/476281.ICMP_315isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
lspA protein networkhttps://string-db.org/network/476281.ICMP_316Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
dapB protein networkhttps://string-db.org/network/476281.ICMP_317Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
carA protein networkhttps://string-db.org/network/476281.ICMP_318Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family.
carB protein networkhttps://string-db.org/network/476281.ICMP_319Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
folA protein networkhttps://string-db.org/network/476281.ICMP_320Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
apaH protein networkhttps://string-db.org/network/476281.ICMP_321Diadenosinetetraphosphatase.
ksgA protein networkhttps://string-db.org/network/476281.ICMP_322Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
pdxA protein networkhttps://string-db.org/network/476281.ICMP_3234-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decar [...]
lrp protein networkhttps://string-db.org/network/476281.ICMP_324DNA-binding transcriptional dual regulator, leucine-binding.
trxB protein networkhttps://string-db.org/network/476281.ICMP_325Thioredoxin reductase, FAD/NAD(P)-binding.
infA protein networkhttps://string-db.org/network/476281.ICMP_326Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
rimK protein networkhttps://string-db.org/network/476281.ICMP_328Ribosomal protein S6 modification protein; Belongs to the RimK family.
dacC protein networkhttps://string-db.org/network/476281.ICMP_329D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
moeA protein networkhttps://string-db.org/network/476281.ICMP_330Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
moeB protein networkhttps://string-db.org/network/476281.ICMP_331Molybdopterin biosynthesis protein MoeB.
hns protein networkhttps://string-db.org/network/476281.ICMP_332Hypothetical protein; Generally suppress horizontally acquired genes.
ICMP_333 protein networkhttps://string-db.org/network/476281.ICMP_333Hypothetical protein.
ICMP_334 protein networkhttps://string-db.org/network/476281.ICMP_334Hypothetical protein.
adk protein networkhttps://string-db.org/network/476281.ICMP_335Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
htpG protein networkhttps://string-db.org/network/476281.ICMP_336Heat shock protein 90; Molecular chaperone. Has ATPase activity.
ybaB protein networkhttps://string-db.org/network/476281.ICMP_337Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
dnaX protein networkhttps://string-db.org/network/476281.ICMP_338DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' t [...]
apt protein networkhttps://string-db.org/network/476281.ICMP_339Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
ppiD protein networkhttps://string-db.org/network/476281.ICMP_341Peptidyl-prolyl cis-trans isomerase.
lon protein networkhttps://string-db.org/network/476281.ICMP_342DNA-binding ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. R [...]
clpX protein networkhttps://string-db.org/network/476281.ICMP_343ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence [...]
clpP protein networkhttps://string-db.org/network/476281.ICMP_344ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
tig protein networkhttps://string-db.org/network/476281.ICMP_345Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs t [...]
bolA protein networkhttps://string-db.org/network/476281.ICMP_346Regulator of penicillin binding proteins and beta lactamase transcription; Belongs to the BolA/IbaG family.
cyoA protein networkhttps://string-db.org/network/476281.ICMP_347Cytochrome o ubiquinol oxidase subunit II.
cyoB protein networkhttps://string-db.org/network/476281.ICMP_348Cytochrome o ubiquinol oxidase subunit I; Belongs to the heme-copper respiratory oxidase family.
cyoC protein networkhttps://string-db.org/network/476281.ICMP_349Cytochrome o ubiquinol oxidase subunit III.
cyoD protein networkhttps://string-db.org/network/476281.ICMP_350Cytochrome o ubiquinol oxidase subunit IV.
cyoE protein networkhttps://string-db.org/network/476281.ICMP_351Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
yajR protein networkhttps://string-db.org/network/476281.ICMP_352Predicted transporter MFS family.
dxs protein networkhttps://string-db.org/network/476281.ICMP_3531-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (D [...]
ibpA protein networkhttps://string-db.org/network/476281.ICMP_354Heat shock chaperone; Belongs to the small heat shock protein (HSP20) family.
sbcB protein networkhttps://string-db.org/network/476281.ICMP_355Exonuclease I.
icd protein networkhttps://string-db.org/network/476281.ICMP_356Isocitrate dehydrogenase.
trmU protein networkhttps://string-db.org/network/476281.ICMP_357tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of [...]
purB protein networkhttps://string-db.org/network/476281.ICMP_358Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
potA protein networkhttps://string-db.org/network/476281.ICMP_359Putrescine/spermidine ABC transporter ATPase protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system [...]
potB protein networkhttps://string-db.org/network/476281.ICMP_360Spermidine/putrescine ABC transporter membrane protein.
potC protein networkhttps://string-db.org/network/476281.ICMP_361Spermidine/putrescine ABC transporter membrane protein.
potD protein networkhttps://string-db.org/network/476281.ICMP_362Spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute [...]
mfd protein networkhttps://string-db.org/network/476281.ICMP_363Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated tr [...]
hinT protein networkhttps://string-db.org/network/476281.ICMP_364Purine nucleoside phosphoramidase.
ycfH protein networkhttps://string-db.org/network/476281.ICMP_365Predicted metallodependent hydrolase.
holB protein networkhttps://string-db.org/network/476281.ICMP_366DNA polymerase III subunit delta'.
tmk protein networkhttps://string-db.org/network/476281.ICMP_367Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
pabC protein networkhttps://string-db.org/network/476281.ICMP_3684-amino-4-deoxychorismate lyase.
acpP protein networkhttps://string-db.org/network/476281.ICMP_369Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
fabG protein networkhttps://string-db.org/network/476281.ICMP_3703-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cy [...]
fabD protein networkhttps://string-db.org/network/476281.ICMP_371Acyl carrier protein S-malonyltransferase.
rpmF protein networkhttps://string-db.org/network/476281.ICMP_37250S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
rluC protein networkhttps://string-db.org/network/476281.ICMP_37323S rRNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
rne protein networkhttps://string-db.org/network/476281.ICMP_374Fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein.
pyrC protein networkhttps://string-db.org/network/476281.ICMP_375Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
yceA protein networkhttps://string-db.org/network/476281.ICMP_376Hypothetical protein; Belongs to the UPF0176 family.
ihfB protein networkhttps://string-db.org/network/476281.ICMP_377Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tran [...]
rpsA protein networkhttps://string-db.org/network/476281.ICMP_37830S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
cmk protein networkhttps://string-db.org/network/476281.ICMP_379Cytidylate kinase.
aroA protein networkhttps://string-db.org/network/476281.ICMP_3803-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
serC protein networkhttps://string-db.org/network/476281.ICMP_381Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belon [...]
glyA protein networkhttps://string-db.org/network/476281.ICMP_382Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
tadA protein networkhttps://string-db.org/network/476281.ICMP_383tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
lpd protein networkhttps://string-db.org/network/476281.ICMP_384Dihydrolipoamide dehydrogenase.
aceF protein networkhttps://string-db.org/network/476281.ICMP_385Dihydrolipoamide acetyltransferase.
aceE protein networkhttps://string-db.org/network/476281.ICMP_386Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
coaE protein networkhttps://string-db.org/network/476281.ICMP_387dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
yacG protein networkhttps://string-db.org/network/476281.ICMP_388Zinc-finger protein.
secA protein networkhttps://string-db.org/network/476281.ICMP_389Translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins [...]
ftsZ protein networkhttps://string-db.org/network/476281.ICMP_390Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
ftsA protein networkhttps://string-db.org/network/476281.ICMP_391Cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
ftsQ protein networkhttps://string-db.org/network/476281.ICMP_392Membrane anchored protein; Involved in growth of wall at septum.
ddlB protein networkhttps://string-db.org/network/476281.ICMP_393D-alanylalanine synthetase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
murC protein networkhttps://string-db.org/network/476281.ICMP_394UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
murG protein networkhttps://string-db.org/network/476281.ICMP_395N-acetylglucosaminyl transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-py [...]
ftsW protein networkhttps://string-db.org/network/476281.ICMP_396Integral membrane protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
murD protein networkhttps://string-db.org/network/476281.ICMP_397UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the Mur [...]
mraY protein networkhttps://string-db.org/network/476281.ICMP_398phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...]
murF protein networkhttps://string-db.org/network/476281.ICMP_399UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murei [...]
murE protein networkhttps://string-db.org/network/476281.ICMP_400UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG [...]
ftsI protein networkhttps://string-db.org/network/476281.ICMP_401Transpeptidase; Involved in septal peptidoglycan synthesis.
ftsL protein networkhttps://string-db.org/network/476281.ICMP_402Membrane bound cell division protein at septum containing leucine zipper motif.
mraW protein networkhttps://string-db.org/network/476281.ICMP_403S-adenosyl-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ilvH protein networkhttps://string-db.org/network/476281.ICMP_404Acetolactate synthase small subunit.
ilvI protein networkhttps://string-db.org/network/476281.ICMP_405Acetolactate synthase III large subunit.
leuA protein networkhttps://string-db.org/network/476281.ICMP_4062-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isoprop [...]
leuB protein networkhttps://string-db.org/network/476281.ICMP_4073-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
leuC protein networkhttps://string-db.org/network/476281.ICMP_408Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
leuD protein networkhttps://string-db.org/network/476281.ICMP_409Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD ty [...]
mhpC protein networkhttps://string-db.org/network/476281.ICMP_4102-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase.
thrS protein networkhttps://string-db.org/network/476281.ICMP_411threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor en [...]
infC protein networkhttps://string-db.org/network/476281.ICMP_412Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
rpmI protein networkhttps://string-db.org/network/476281.ICMP_41350S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
rplT protein networkhttps://string-db.org/network/476281.ICMP_41450S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
pheS protein networkhttps://string-db.org/network/476281.ICMP_415phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
pheT protein networkhttps://string-db.org/network/476281.ICMP_416phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
ihfA protein networkhttps://string-db.org/network/476281.ICMP_417Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tra [...]
ychF protein networkhttps://string-db.org/network/476281.ICMP_418Translation-associated GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
pth protein networkhttps://string-db.org/network/476281.ICMP_419peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
prsA protein networkhttps://string-db.org/network/476281.ICMP_420Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
ICMP_421 protein networkhttps://string-db.org/network/476281.ICMP_421Hypothetical protein.
ICMP_422 protein networkhttps://string-db.org/network/476281.ICMP_422Hypothetical protein.
prfA protein networkhttps://string-db.org/network/476281.ICMP_423Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
prmC protein networkhttps://string-db.org/network/476281.ICMP_424N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally [...]
yghA protein networkhttps://string-db.org/network/476281.ICMP_425Oxidoreductase.
astE protein networkhttps://string-db.org/network/476281.ICMP_426Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
yebQ protein networkhttps://string-db.org/network/476281.ICMP_427Predicted transporter; MFS family.
fumC protein networkhttps://string-db.org/network/476281.ICMP_428Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
rsxA protein networkhttps://string-db.org/network/476281.ICMP_429Integral membrane protein of SoxR-reducing complex; Belongs to the NqrDE/RnfAE family.
rsxB protein networkhttps://string-db.org/network/476281.ICMP_430Member of SoxR-reducing complex; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
rsxC protein networkhttps://string-db.org/network/476281.ICMP_431Member of SoxR-reducing complex; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin fam [...]
rsxD protein networkhttps://string-db.org/network/476281.ICMP_432Member of SoxR-reducing complex; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.
ICMP_433 protein networkhttps://string-db.org/network/476281.ICMP_433Hypothetical protein.
rsxE protein networkhttps://string-db.org/network/476281.ICMP_434Integral membrane protein of SoxR-reducing complex; Belongs to the NqrDE/RnfAE family.
nth protein networkhttps://string-db.org/network/476281.ICMP_435DNA glycosylase and apyrimidinic (AP) lyase.
tppB protein networkhttps://string-db.org/network/476281.ICMP_436Putative tripeptide transporter permease.
tyrS protein networkhttps://string-db.org/network/476281.ICMP_437tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
rnt protein networkhttps://string-db.org/network/476281.ICMP_438Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP [...]
ydhD protein networkhttps://string-db.org/network/476281.ICMP_439Hypothetical protein; Belongs to the glutaredoxin family. Monothiol subfamily.
ribC protein networkhttps://string-db.org/network/476281.ICMP_440Riboflavin synthase subunit alpha.
pykF protein networkhttps://string-db.org/network/476281.ICMP_442Pyruvate kinase; Belongs to the pyruvate kinase family.
sufE protein networkhttps://string-db.org/network/476281.ICMP_443Cysteine desufuration protein SufE.
sufS protein networkhttps://string-db.org/network/476281.ICMP_444Selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomo [...]
sufD protein networkhttps://string-db.org/network/476281.ICMP_445Component of SufBCD complex.
sufC protein networkhttps://string-db.org/network/476281.ICMP_446Cysteine desulfurase ATPase component.
sufB protein networkhttps://string-db.org/network/476281.ICMP_447Component of SufBCD complex.
sufA protein networkhttps://string-db.org/network/476281.ICMP_448Iron-sulfur cluster assembly scaffold protein; Belongs to the HesB/IscA family.
acpS protein networkhttps://string-db.org/network/476281.ICMP_4494'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
pdxJ protein networkhttps://string-db.org/network/476281.ICMP_450Pyridoxal phosphate biosynthetic protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate [...]
era protein networkhttps://string-db.org/network/476281.ICMP_451GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly als [...]
rnc protein networkhttps://string-db.org/network/476281.ICMP_452Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
lepB protein networkhttps://string-db.org/network/476281.ICMP_453Leader peptidase; Belongs to the peptidase S26 family.
lepA protein networkhttps://string-db.org/network/476281.ICMP_454GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
ung protein networkhttps://string-db.org/network/476281.ICMP_455uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
grpE protein networkhttps://string-db.org/network/476281.ICMP_456Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the n [...]
yfjB protein networkhttps://string-db.org/network/476281.ICMP_457Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosph [...]
yfjF protein networkhttps://string-db.org/network/476281.ICMP_458Hypothetical protein; Belongs to the UPF0125 (RnfH) family.
smpB protein networkhttps://string-db.org/network/476281.ICMP_459SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
yba2 protein networkhttps://string-db.org/network/476281.ICMP_461Hypothetical protein.
hisG protein networkhttps://string-db.org/network/476281.ICMP_462ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
hisD protein networkhttps://string-db.org/network/476281.ICMP_463Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisC protein networkhttps://string-db.org/network/476281.ICMP_464Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
hisB protein networkhttps://string-db.org/network/476281.ICMP_465Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; In the N-terminal section; belongs to the histidinol- phosphatase family.
hisH protein networkhttps://string-db.org/network/476281.ICMP_466Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glu [...]
hisA protein networkhttps://string-db.org/network/476281.ICMP_467N-(5'-phospho-L-ribosyl-formimino)-5-amino-1- (5'-phosphoribosyl)-4-imidazolecarboxamide isomerase.
hisF protein networkhttps://string-db.org/network/476281.ICMP_468Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that prod [...]
hisI protein networkhttps://string-db.org/network/476281.ICMP_469Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.
gnd protein networkhttps://string-db.org/network/476281.ICMP_4706-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
dcd protein networkhttps://string-db.org/network/476281.ICMP_471Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
ybhL protein networkhttps://string-db.org/network/476281.ICMP_472Predicted inner membrane protein; Belongs to the BI1 family.
moaE protein networkhttps://string-db.org/network/476281.ICMP_473Molybdopterin synthase large subunit.
moaD protein networkhttps://string-db.org/network/476281.ICMP_474Molybdopterin synthase small subunit.
bioD protein networkhttps://string-db.org/network/476281.ICMP_475Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ur [...]
bioC protein networkhttps://string-db.org/network/476281.ICMP_476Predicted methltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize [...]
bioF protein networkhttps://string-db.org/network/476281.ICMP_4778-amino-7-oxononanoate synthase.
bioB protein networkhttps://string-db.org/network/476281.ICMP_478Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily [...]
bioA protein networkhttps://string-db.org/network/476281.ICMP_479Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-di [...]
ybhE protein networkhttps://string-db.org/network/476281.ICMP_4806-phosphogluconolactonase.
gpmA protein networkhttps://string-db.org/network/476281.ICMP_481Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
sucD protein networkhttps://string-db.org/network/476281.ICMP_482succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus rep [...]
sucC protein networkhttps://string-db.org/network/476281.ICMP_483succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus repr [...]
sucB protein networkhttps://string-db.org/network/476281.ICMP_484Dihydrolipoamide acetyltransferase.
sucA protein networkhttps://string-db.org/network/476281.ICMP_485Alpha-ketoglutarate decarboxylase.
sdhB protein networkhttps://string-db.org/network/476281.ICMP_486Succinate dehydrogenase FeS subunit.
sdhA protein networkhttps://string-db.org/network/476281.ICMP_487Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
sdhD protein networkhttps://string-db.org/network/476281.ICMP_488Succinate dehydrogenase cytochrome b556 small membrane subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
sdhC protein networkhttps://string-db.org/network/476281.ICMP_489Succinate dehydrogenase cytochrome b556 large membrane subunit.
gltA protein networkhttps://string-db.org/network/476281.ICMP_490Citrate synthase; Belongs to the citrate synthase family.
fldA protein networkhttps://string-db.org/network/476281.ICMP_493Flavodoxin 1; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
glnS protein networkhttps://string-db.org/network/476281.ICMP_494glutaminyl-tRNA synthetase.
ICMP_499 protein networkhttps://string-db.org/network/476281.ICMP_499Hypothetical protein.
miaB protein networkhttps://string-db.org/network/476281.ICMP_500Isopentenyl-adenosine A37 tRNA methylthiolase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i [...]
ybeZ protein networkhttps://string-db.org/network/476281.ICMP_501Predicted protein with nucleoside triphosphate hydrolase domain.
ybeY protein networkhttps://string-db.org/network/476281.ICMP_502Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
leuS protein networkhttps://string-db.org/network/476281.ICMP_503leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
holA protein networkhttps://string-db.org/network/476281.ICMP_504DNA polymerase III subunit delta.
ICMP_505 protein networkhttps://string-db.org/network/476281.ICMP_505Hypothetical protein.
mrdA protein networkhttps://string-db.org/network/476281.ICMP_506Transpeptidase; Penicillin-binding protein 2.
mrdB protein networkhttps://string-db.org/network/476281.ICMP_507Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
lipB protein networkhttps://string-db.org/network/476281.ICMP_508Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act [...]
lipA protein networkhttps://string-db.org/network/476281.ICMP_509Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, there [...]
cspE protein networkhttps://string-db.org/network/476281.ICMP_510Cold shock protein E.
allC protein networkhttps://string-db.org/network/476281.ICMP_511N-carbamoyl-L-amino acid amidohydrolase.
ICMP_512 protein networkhttps://string-db.org/network/476281.ICMP_512Aminotransferase class V.
ggt protein networkhttps://string-db.org/network/476281.ICMP_513Gamma-glutamyltranspeptidase periplasmic precursor.
ICMP_514 protein networkhttps://string-db.org/network/476281.ICMP_514Hypothetical protein.
ICMP_515 protein networkhttps://string-db.org/network/476281.ICMP_515Amidase; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A related.
ICMP_516 protein networkhttps://string-db.org/network/476281.ICMP_516Polysaccharide deacetylase xylanase.
ICMP_517 protein networkhttps://string-db.org/network/476281.ICMP_517Asp/glu racemase.
dnaQ protein networkhttps://string-db.org/network/476281.ICMP_518DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing funct [...]
rnhA protein networkhttps://string-db.org/network/476281.ICMP_519Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
gloB protein networkhttps://string-db.org/network/476281.ICMP_520Predicted hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
purH protein networkhttps://string-db.org/network/476281.ICMP_521Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.
hupA protein networkhttps://string-db.org/network/476281.ICMP_522HU DNA-binding transcriptional regulator alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme envir [...]
hemE protein networkhttps://string-db.org/network/476281.ICMP_523Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
rpoC protein networkhttps://string-db.org/network/476281.ICMP_524DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/476281.ICMP_525DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/476281.ICMP_52650S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the ba [...]
rplJ protein networkhttps://string-db.org/network/476281.ICMP_52750S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
rplA protein networkhttps://string-db.org/network/476281.ICMP_52850S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/476281.ICMP_52950S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/476281.ICMP_530Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA [...]
secE protein networkhttps://string-db.org/network/476281.ICMP_531Translocase; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61- [...]
tufB-2 protein networkhttps://string-db.org/network/476281.ICMP_532Protein chain elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
birA protein networkhttps://string-db.org/network/476281.ICMP_537Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate [...]
murB protein networkhttps://string-db.org/network/476281.ICMP_538UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
clpB protein networkhttps://string-db.org/network/476281.ICMP_539Protein disaggregation chaperone; Belongs to the ClpA/ClpB family.
rluD protein networkhttps://string-db.org/network/476281.ICMP_54023S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
rluD-2 protein networkhttps://string-db.org/network/476281.ICMP_54123S rRNA pseudouridine synthase.
yfiO protein networkhttps://string-db.org/network/476281.ICMP_542Predicted lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, th [...]
pheA protein networkhttps://string-db.org/network/476281.ICMP_543Fused chorismate mutase P/prephenate dehydratase.
tyrA protein networkhttps://string-db.org/network/476281.ICMP_544Fused chorismate mutase T/prephenate dehydrogenase.
aroF protein networkhttps://string-db.org/network/476281.ICMP_5453-deoxy-D-arabino-heptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7- [...]
rplS protein networkhttps://string-db.org/network/476281.ICMP_54650S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
trmD protein networkhttps://string-db.org/network/476281.ICMP_547tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rimM protein networkhttps://string-db.org/network/476281.ICMP_54816S rRNA-processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Ess [...]
rpsP protein networkhttps://string-db.org/network/476281.ICMP_54930S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
ffh protein networkhttps://string-db.org/network/476281.ICMP_550Signal recognition particle component; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nas [...]
luxS protein networkhttps://string-db.org/network/476281.ICMP_551S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the enviro [...]
gshA protein networkhttps://string-db.org/network/476281.ICMP_552Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
csrA protein networkhttps://string-db.org/network/476281.ICMP_555Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid g [...]
alaS protein networkhttps://string-db.org/network/476281.ICMP_556alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
recA protein networkhttps://string-db.org/network/476281.ICMP_557Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of ho [...]
metK protein networkhttps://string-db.org/network/476281.ICMP_558S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet forma [...]
galP protein networkhttps://string-db.org/network/476281.ICMP_559D-galactose (H+ symport)transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
gshB protein networkhttps://string-db.org/network/476281.ICMP_560Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
yqgE protein networkhttps://string-db.org/network/476281.ICMP_561Hypothetical protein; Belongs to the UPF0301 (AlgH) family.
yqgF protein networkhttps://string-db.org/network/476281.ICMP_562Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
yggS protein networkhttps://string-db.org/network/476281.ICMP_563Predicted enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
yggW protein networkhttps://string-db.org/network/476281.ICMP_564Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. [...]
yggH protein networkhttps://string-db.org/network/476281.ICMP_565tRNA(m7G46)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
yggX protein networkhttps://string-db.org/network/476281.ICMP_566Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
deoD protein networkhttps://string-db.org/network/476281.ICMP_567Purine nucleoside phosphorylase.
deoB protein networkhttps://string-db.org/network/476281.ICMP_568Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
metC protein networkhttps://string-db.org/network/476281.ICMP_569Cystathionine beta-lyase.
ribB protein networkhttps://string-db.org/network/476281.ICMP_5703,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
cca protein networkhttps://string-db.org/network/476281.ICMP_571Fused tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without usin [...]
folB protein networkhttps://string-db.org/network/476281.ICMP_572Bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
ygjD protein networkhttps://string-db.org/network/476281.ICMP_573O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in t [...]
rpsU protein networkhttps://string-db.org/network/476281.ICMP_57430S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
dnaG protein networkhttps://string-db.org/network/476281.ICMP_575DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpoD protein networkhttps://string-db.org/network/476281.ICMP_576RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primar [...]
pmbA protein networkhttps://string-db.org/network/476281.ICMP_577Predicted peptidase; Required for the maturation and secretion of the antibiotic peptide MccB17.
yraL protein networkhttps://string-db.org/network/476281.ICMP_578Predicted methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
yqjK protein networkhttps://string-db.org/network/476281.ICMP_580Hypothetial protein.
yqjE protein networkhttps://string-db.org/network/476281.ICMP_581Conserved inner membrane protein.
yqjD protein networkhttps://string-db.org/network/476281.ICMP_582Hypothetical protein.
ydeP protein networkhttps://string-db.org/network/476281.ICMP_584Predicted oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
rplY protein networkhttps://string-db.org/network/476281.ICMP_58650S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
yccK protein networkhttps://string-db.org/network/476281.ICMP_590Predicted sulfite reductase subunit; Part of a sulfur-relay system.
ycaR protein networkhttps://string-db.org/network/476281.ICMP_591Hypothetical protein; Belongs to the UPF0434 family.
ycbL protein networkhttps://string-db.org/network/476281.ICMP_592Predicted metal-binding enzyme.
aspC protein networkhttps://string-db.org/network/476281.ICMP_593Aspartate aminotransferase.
asnS protein networkhttps://string-db.org/network/476281.ICMP_594asparaginyl-tRNA synthetase.
pyrD protein networkhttps://string-db.org/network/476281.ICMP_595Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
yccV protein networkhttps://string-db.org/network/476281.ICMP_596DNA-binding protein.
metF protein networkhttps://string-db.org/network/476281.ICMP_5985,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
metB protein networkhttps://string-db.org/network/476281.ICMP_599Cystathionine gamma-synthase.
rpmE protein networkhttps://string-db.org/network/476281.ICMP_60050S ribosomal subunit protein L31; Binds the 23S rRNA.
priA protein networkhttps://string-db.org/network/476281.ICMP_601Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex [...]
ftsN protein networkhttps://string-db.org/network/476281.ICMP_602Essential cell division protein.
hslV protein networkhttps://string-db.org/network/476281.ICMP_603ATP-dependent protease peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
hslU protein networkhttps://string-db.org/network/476281.ICMP_604ATP-dependent protease ATP-binding subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU [...]
sfcA protein networkhttps://string-db.org/network/476281.ICMP_605Malate dehydrogenase.
metG protein networkhttps://string-db.org/network/476281.ICMP_606methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
ahpC protein networkhttps://string-db.org/network/476281.ICMP_607Alkyl hydroperoxide reductase C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role [...]
argS protein networkhttps://string-db.org/network/476281.ICMP_610arginyl-tRNA synthetase.
aspS protein networkhttps://string-db.org/network/476281.ICMP_611aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
ruvC protein networkhttps://string-db.org/network/476281.ICMP_612Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the sam [...]
fxsA protein networkhttps://string-db.org/network/476281.ICMP_614Inner membrane protein.
aspA protein networkhttps://string-db.org/network/476281.ICMP_615Aspartate ammonia-lyase.
cutA protein networkhttps://string-db.org/network/476281.ICMP_616Copper binding protein.
yjcE protein networkhttps://string-db.org/network/476281.ICMP_618Predicted cation/proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36 [...]
ssb protein networkhttps://string-db.org/network/476281.ICMP_619Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of actio [...]
dnaB protein networkhttps://string-db.org/network/476281.ICMP_620Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
pgi protein networkhttps://string-db.org/network/476281.ICMP_621Glucose-6-phosphate isomerase; Belongs to the GPI family.
metA protein networkhttps://string-db.org/network/476281.ICMP_622Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
tatC protein networkhttps://string-db.org/network/476281.ICMP_623TatABCE protein translocation system subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their [...]
tatB protein networkhttps://string-db.org/network/476281.ICMP_624Sec-independent translocase.
tatA protein networkhttps://string-db.org/network/476281.ICMP_625Twin argininte translocase protein A; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal p [...]
metE protein networkhttps://string-db.org/network/476281.ICMP_6265-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; [...]
yigL protein networkhttps://string-db.org/network/476281.ICMP_627Predicted hydrolase Glucosamine 6-phosphatase.
corA protein networkhttps://string-db.org/network/476281.ICMP_628Magnesium/nickel/cobalt transporter; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
uvrD protein networkhttps://string-db.org/network/476281.ICMP_629DNA-dependent ATPase I and helicase II.
dapF protein networkhttps://string-db.org/network/476281.ICMP_630Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
hemC protein networkhttps://string-db.org/network/476281.ICMP_631Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
hemD protein networkhttps://string-db.org/network/476281.ICMP_632uroporphyrinogen-III synthetase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
rho protein networkhttps://string-db.org/network/476281.ICMP_637Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
trxA protein networkhttps://string-db.org/network/476281.ICMP_638Thioredoxin; Belongs to the thioredoxin family.
aroK protein networkhttps://string-db.org/network/476281.ICMP_639Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
aroB protein networkhttps://string-db.org/network/476281.ICMP_6403-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
rpe protein networkhttps://string-db.org/network/476281.ICMP_641Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
trpS protein networkhttps://string-db.org/network/476281.ICMP_642tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
fpr protein networkhttps://string-db.org/network/476281.ICMP_643flavodoxin-NADP reductase.
tpiA protein networkhttps://string-db.org/network/476281.ICMP_644Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
pfkA protein networkhttps://string-db.org/network/476281.ICMP_6456-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
cysE protein networkhttps://string-db.org/network/476281.ICMP_646Serine acetyltransferase; Belongs to the transferase hexapeptide repeat family.
grxC protein networkhttps://string-db.org/network/476281.ICMP_647Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
mutM protein networkhttps://string-db.org/network/476281.ICMP_648formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a [...]
rpmG protein networkhttps://string-db.org/network/476281.ICMP_64950S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/476281.ICMP_65050S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
dut protein networkhttps://string-db.org/network/476281.ICMP_651Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intrace [...]
pyrE protein networkhttps://string-db.org/network/476281.ICMP_652Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
yicC protein networkhttps://string-db.org/network/476281.ICMP_653Hypothetical protein.
gmk protein networkhttps://string-db.org/network/476281.ICMP_654Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
rpoZ protein networkhttps://string-db.org/network/476281.ICMP_655DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alp [...]
bipA protein networkhttps://string-db.org/network/476281.ICMP_656GTP-binding protein.
yihA protein networkhttps://string-db.org/network/476281.ICMP_657GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase fam [...]
polA protein networkhttps://string-db.org/network/476281.ICMP_658DNA polymerase I.
polA-2 protein networkhttps://string-db.org/network/476281.ICMP_659DNA polymerase I.
mobA protein networkhttps://string-db.org/network/476281.ICMP_660Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine din [...]