Organism Overview: Schizosaccharomyces pombe


 
eaf1 protein networkhttps://string-db.org/network/284812.A0ZWU1Ell1-associated factor 1; Activates transcription elongation by RNA polymerase II and pyrophosphorolysis as a complex with ell1. Acts as a transcriptional transactivator of ell1 elongation activi [...]
SPAC23C4.04c protein networkhttps://string-db.org/network/284812.A6X970Putative uncharacterized protein C23C4.04c.
gon7 protein networkhttps://string-db.org/network/284812.A6X972EKC/KEOPS complex subunit gon7; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons [...]
sfc7 protein networkhttps://string-db.org/network/284812.A6X980Transcription factor tau subunit sfc7; TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the i [...]
SPBC15D4.13c protein networkhttps://string-db.org/network/284812.A6X982Uncharacterized protein C15D4.13c.
lsd90 protein networkhttps://string-db.org/network/284812.A9ZLL8Protein lsd90; May be involved in the metabolism of very long-chain fatty acid-containing phospholipids (VLCFA-PL).
SPBC460.01c protein networkhttps://string-db.org/network/284812.B5BP45Uncharacterized amino-acid permease C460.01c.
SPBC460.02c protein networkhttps://string-db.org/network/284812.B5BP46Putative glutathione S-transferase C460.02c; Involved in the oxidative stress response and detoxification.
vba2 protein networkhttps://string-db.org/network/284812.B5BP47Uncharacterized transporter C460.03.
SPBC460.04c protein networkhttps://string-db.org/network/284812.B5BP48Putative alpha-ketoglutarate-dependent sulfonate dioxygenase; Acts as an alpha-ketoglutarate-dependent dioxygenase active on sulfonates.
SPBC460.05 protein networkhttps://string-db.org/network/284812.B5BP49Uncharacterized transporter C460.05.
iec5 protein networkhttps://string-db.org/network/284812.B8Y7Y5INO80 complex subunit 5; Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
atp19 protein networkhttps://string-db.org/network/284812.C6Y4A3ATP synthase subunit K, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
SPAC6F6.19 protein networkhttps://string-db.org/network/284812.C6Y4A5Uncharacterized protein C6F6.19.
emc5 protein networkhttps://string-db.org/network/284812.C6Y4A7ER membrane protein complex subunit 5; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).
lam4 protein networkhttps://string-db.org/network/284812.C6Y4A8Uncharacterized protein C23D3.16.
pga1 protein networkhttps://string-db.org/network/284812.C6Y4B3GPI mannosyltransferase 2 subunit C167.09; Essential component of the GPI mannosyltransferase 2 complex. Responsible for the transfer of the second mannose to the glycosylphosphatidylinositol dur [...]
SPAC23H4.21 protein networkhttps://string-db.org/network/284812.C6Y4B4Uncharacterized protein C23H4.21.
SPAC212.12 protein networkhttps://string-db.org/network/284812.C6Y4B5Uncharacterized GPI-anchored protein SPAC212.12.
nce101 protein networkhttps://string-db.org/network/284812.C6Y4B6Non-classical export protein 1; Involved in a novel pathway of export of proteins that lack a cleavable signal sequence. May be part of the export machinery or may also be a substrate for non-cla [...]
SPAC227.19c protein networkhttps://string-db.org/network/284812.C6Y4B7Uncharacterized protein C227.19c.
aim41 protein networkhttps://string-db.org/network/284812.C6Y4B8Uncharacterized protein C22F3.15.
SPAC222.18 protein networkhttps://string-db.org/network/284812.C6Y4C0Putative splicing factor C222.18; Has a role in pre-mRNA splicing where it is involved in spliceosome assembly; Belongs to the splicing factor SR family.
pet117 protein networkhttps://string-db.org/network/284812.C6Y4C1Protein pet117, mitochondrial; Involved in the assembly of cytochrome c oxidase. Belongs to the PET117 family.
spo2 protein networkhttps://string-db.org/network/284812.C6Y4C2Sporulation-specific protein 2; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membra [...]
ecl3 protein networkhttps://string-db.org/network/284812.C6Y4C3Extender of the chronological lifespan protein ecl3; Involved in chronological cell aging.
sdh8 protein networkhttps://string-db.org/network/284812.C6Y4C4Succinate dehydrogenase assembly factor 4, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) [...]
ecl2 protein networkhttps://string-db.org/network/284812.C6Y4C5Extender of the chronological lifespan protein 2; Involved in chronological cell aging.
lam1 protein networkhttps://string-db.org/network/284812.C6Y4C6Uncharacterized protein C29A10.17.
cox14 protein networkhttps://string-db.org/network/284812.C6Y4C7Uncharacterized membrane protein C757.15.
vma21 protein networkhttps://string-db.org/network/284812.C6Y4C8Vacuolar ATPase assembly integral membrane protein vma21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family.
spo13 protein networkhttps://string-db.org/network/284812.C6Y4C9Sporulation-specific protein 13; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membr [...]
dpb3 protein networkhttps://string-db.org/network/284812.C6Y4D0DNA polymerase epsilon subunit C; As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication. It is required during synthesis of the lead [...]
mrp49 protein networkhttps://string-db.org/network/284812.C6Y4D2Probable 54S ribosomal protein MRP49, mitochondrial; Involved in mitochondrial translation.
ecl1 protein networkhttps://string-db.org/network/284812.C6Y4D3Extender of the chronological lifespan protein 1; Involved in chronological cell aging. Extends cell viability after entry into the stationary phase probably through affecting the Pka1-dependent [...]
lam3 protein networkhttps://string-db.org/network/284812.G2TRJ4Uncharacterized protein tam1.
tam6 protein networkhttps://string-db.org/network/284812.G2TRJ5Uncharacterized protein tam6, mitochondrial; To yeast YDL157C.
cmc4 protein networkhttps://string-db.org/network/284812.G2TRJ8Cx9C motif-containing protein 4, mitochondrial.
coa3 protein networkhttps://string-db.org/network/284812.G2TRJ9Cytochrome c oxidase assembly factor 3, mitochondrial; Required for assembly of cytochrome c oxidase (complex IV). Belongs to the COA3 family.
gem6 protein networkhttps://string-db.org/network/284812.G2TRK8Uncharacterized protein new12.
new13 protein networkhttps://string-db.org/network/284812.G2TRK9Uncharacterized protein new13.
SPAC186.04c protein networkhttps://string-db.org/network/284812.G2TRL1Uncharacterized protein C186.04c.
wip1 protein networkhttps://string-db.org/network/284812.G2TRL2Inner kinetochore subunit wip1; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segre [...]
rsa3 protein networkhttps://string-db.org/network/284812.G2TRL3Ribosome assembly protein 3; Required for efficient biogenesis of the 60S ribosomal subunit.
pop6 protein networkhttps://string-db.org/network/284812.G2TRL5Uncharacterized protein new2.
spd2 protein networkhttps://string-db.org/network/284812.G2TRL7S-phase delaying protein 2; Regulates the ribonucleotide reductase activity. Belongs to the DIF1/spd1 family.
ppt2 protein networkhttps://string-db.org/network/284812.G2TRL9Putative holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
new4 protein networkhttps://string-db.org/network/284812.G2TRM6Uncharacterized protein new4.
tam5 protein networkhttps://string-db.org/network/284812.G2TRM7Uncharacterized protein tam5.
erh1 protein networkhttps://string-db.org/network/284812.G2TRN4Enhancer of rudimentary homolog; May have a role in the cell cycle; Belongs to the E(R) family.
smp1 protein networkhttps://string-db.org/network/284812.G2TRN5Uncharacterized protein C25B8.20.
SPAC750.01 protein networkhttps://string-db.org/network/284812.G2TRN6Putative aryl-alcohol dehydrogenase C750.01; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
SPAC212.06c protein networkhttps://string-db.org/network/284812.G2TRN7RecQ DNA helicase-like protein C212.06c; Truncated ATP-dependent 3' to 5' DNA helicase.
SPAC11D3.11c protein networkhttps://string-db.org/network/284812.G2TRN9Uncharacterized transcriptional regulatory protein C11D3.11c.
mim2 protein networkhttps://string-db.org/network/284812.G2TRP0Mitochondrial import protein 2; Component of the MIM complex required for outer membrane protein import (By similarity). Involved in import of the subset of proteins with multiple alpha-helical t [...]
SPBC30B4.09 protein networkhttps://string-db.org/network/284812.G2TRP1Putative uncharacterized protein C30B4.09.
new15 protein networkhttps://string-db.org/network/284812.G2TRP2Putative mitochondrial ribosomal protein new15, mitochondrial.
kgd4 protein networkhttps://string-db.org/network/284812.G2TRP337S ribosomal protein YMR-31, mitochondrial.
cox7 protein networkhttps://string-db.org/network/284812.G2TRP5Cytochrome c oxidase subunit 7; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain [...]
coa6 protein networkhttps://string-db.org/network/284812.G2TRP6Cytochrome c oxidase subunit 6B-like protein new16; Involved in cytochrome c oxidase complex assembly and is required for efficient formation of respiratory supercomplexes comprised of complexes [...]
tom5 protein networkhttps://string-db.org/network/284812.G2TRP7Mitochondrial import receptor subunit tom5; Component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mi [...]
mzm1 protein networkhttps://string-db.org/network/284812.G2TRP8Mitochondrial zinc maintenance protein 1, mitochondrial; Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, bin [...]
cox20 protein networkhttps://string-db.org/network/284812.G2TRP9Cytochrome c oxidase assembly protein cox20, mitochondrial; Involved in the assembly of the cytochrome oxidase complex. Required for the maturation and subsequent assembly of the mitochondrially [...]
SPBC32H8.15 protein networkhttps://string-db.org/network/284812.G2TRQ1Putative uncharacterized protein C32H8.15.
tam9 protein networkhttps://string-db.org/network/284812.G2TRQ854S ribosomal protein L36, mitochondrial.
gem7 protein networkhttps://string-db.org/network/284812.G2TRR1Gem-associated protein 7 homolog.
spc1 protein networkhttps://string-db.org/network/284812.G2TRR4Microsomal signal peptidase subunit 1; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endo [...]
smp2 protein networkhttps://string-db.org/network/284812.G2TRR7Putative uncharacterized protein C13G1.16.
SPBPB21E7.10 protein networkhttps://string-db.org/network/284812.G2TRR8Uncharacterized protein PB21E7.10.
new14 protein networkhttps://string-db.org/network/284812.G2TRS1Uncharacterized protein new14.
new20 protein networkhttps://string-db.org/network/284812.G2TRS2Uncharacterized protein new20.
ksh1 protein networkhttps://string-db.org/network/284812.G2TRS3Protein kish; Involved in the early part of the secretory pathway.
SPBC713.13 protein networkhttps://string-db.org/network/284812.G2TRS5Putative uncharacterized transmembrane protein SPBC713.13.
SPBC1348.13 protein networkhttps://string-db.org/network/284812.G2TRS8Cox1 intron-like protein SPBC1348.13.
SPBC337.02c protein networkhttps://string-db.org/network/284812.G2TRS9UPF0612 protein C337.02c; Belongs to the UPF0612 family.
ric8 protein networkhttps://string-db.org/network/284812.G2TRT0Synembryn-like protein C3E7.04c; Probable guanine nucleotide exchange factor (GEF). Belongs to the synembryn family.
SPBC1348.12 protein networkhttps://string-db.org/network/284812.G2TRT1Probable transcriptional repressor C1348.12; Probable transcriptional repressor of multidrug resistance genes.
tam14 protein networkhttps://string-db.org/network/284812.G2TRT3Protein tam14; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct [...]
new25 protein networkhttps://string-db.org/network/284812.G2TRT4SAP domain-containing new25.
SPCC1235.18 protein networkhttps://string-db.org/network/284812.G2TRT8Putative uncharacterized transmembrane protein C1235.18.
SPCC794.16 protein networkhttps://string-db.org/network/284812.G2TRT9Putative uncharacterized protein SPCC794.16.
ost5 protein networkhttps://string-db.org/network/284812.G2TRU0Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost5; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3 [...]
smp4 protein networkhttps://string-db.org/network/284812.G2TRU3Uncharacterized protein PB16A4.07.
cmc2 protein networkhttps://string-db.org/network/284812.G2TRU5COX assembly mitochondrial protein 2; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.
wtf17 protein networkhttps://string-db.org/network/284812.G2TRU8Uncharacterized protein wtf17.
wtf8 protein networkhttps://string-db.org/network/284812.G2TRV0Uncharacterized protein wtf8.
ure2 protein networkhttps://string-db.org/network/284812.O00084Urease.
dld1 protein networkhttps://string-db.org/network/284812.O00087Dihydrolipoyl dehydrogenase, mitochondrial; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes (By similarity). Malfunction of this protein blocks the progressio [...]
zwf1 protein networkhttps://string-db.org/network/284812.O00091Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolys [...]
ubc7 protein networkhttps://string-db.org/network/284812.O00102Ubiquitin-conjugating enzyme E2-18 kDa; Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in degradation of misfolded or regulated proteins localized in the endoplasmic [...]
ubc11 protein networkhttps://string-db.org/network/284812.O00103Ubiquitin-conjugating enzyme E2-20 kDa; Catalyzes the covalent attachment of ubiquitin to other proteins.
taf5 protein networkhttps://string-db.org/network/284812.O13282Transcription initiation factor TFIID subunit 5; TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcription. R [...]
srw1 protein networkhttps://string-db.org/network/284812.O13286WD repeat-containing protein srw1; Has a role in cell differentiation and cell cycling by negatively regulating cig2 and cdc12-associated cdc2. Down-regulates the level of cdc13, particularly in [...]
dhc1 protein networkhttps://string-db.org/network/284812.O13290Dynein heavy chain, cytoplasmic; Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force- [...]
hos2 protein networkhttps://string-db.org/network/284812.O13298Histone deacetylase phd1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation plays an important role in [...]
orb6 protein networkhttps://string-db.org/network/284812.O13310Serine/threonine-protein kinase orb6; Interacts with pak1/shk1 and coordinates cell morphogenesis with the cell cycle. It is essential for maintenance of cell polarity and is involved in mitotic [...]
met17 protein networkhttps://string-db.org/network/284812.O13326Homocysteine synthase; Catalyzes the conversion of O-acetyl-L-homoserine (OAH) into homocysteine in the methionine biosynthesis pathway. Can also use O-succinyl-L-homoserine and L-homoserine as s [...]
trt1 protein networkhttps://string-db.org/network/284812.O13339Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcri [...]
pmt3 protein networkhttps://string-db.org/network/284812.O13351Ubiquitin-like protein pmt3/smt3; Required for chromosome segregation where it may be involved in microtubule assembly. Loss of smt3 leads to an increase in telomere length; Belongs to the ubiqui [...]
sum3 protein networkhttps://string-db.org/network/284812.O13370ATP-dependent RNA helicase ded1; ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation [...]
pmp1 protein networkhttps://string-db.org/network/284812.O13453Tyrosine-protein phosphatase pmp1; Dual specificity phosphatase that dephosphorylates MAP kinase pmk1 on a Tyr. Has a role in chloride ion homeostasis by inactivating this pmk1 MAP kinase pathway [...]
wwm1 protein networkhttps://string-db.org/network/284812.O13598WW domain-containing protein C11B10.08.
sws1 protein networkhttps://string-db.org/network/284812.O13600Zinc finger SWIM domain-containing protein sws1; Involved in early stages of the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or indu [...]
rsp1 protein networkhttps://string-db.org/network/284812.O13601DnaJ-related protein rsp1; Has a role in the proper organization of the interphase microtubule cytoskeleton. Required for equatorial microtubule organizing center (eMTOC) disassembly into satelli [...]
mrps28 protein networkhttps://string-db.org/network/284812.O13602Probable 37S ribosomal protein S28, mitochondrial; Essential component of the small mitochondrial ribosomal subunit; Belongs to the universal ribosomal protein uS15 family.
mei4 protein networkhttps://string-db.org/network/284812.O13606Meiosis-specific transcription factor mei4; Functions as a meiosis-specific transcription factor. Binds to the 5'-GTAAAYA-3' consensus sequence of the promoter of the spo6 gene.
utp24 protein networkhttps://string-db.org/network/284812.O13610rRNA-processing protein fcf1; Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly. Required for the early cleavage steps of 35S rRNA at the A(0), A(1), and A(2) s [...]
nep2 protein networkhttps://string-db.org/network/284812.O13612NEDD8-specific protease 2; Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted protei [...]
rps1002 protein networkhttps://string-db.org/network/284812.O1361440S ribosomal protein S10-B.
prp5 protein networkhttps://string-db.org/network/284812.O13615Pre-mRNA-splicing factor prp5; Required for both cell cycle progression at G2/M and pre-mRNA splicing. Interacts genetically with the PRP4 kinase. Belongs to the WD repeat PRL1/PRL2 family.
sbg1 protein networkhttps://string-db.org/network/284812.O13619Uncharacterized protein P22H7.03.
mrd1 protein networkhttps://string-db.org/network/284812.O13620Multiple RNA-binding domain-containing protein 1; Involved in pre-rRNA processing; Belongs to the RRM MRD1 family.
ist2 protein networkhttps://string-db.org/network/284812.O13621Uncharacterized protein C691.05c.
mss116 protein networkhttps://string-db.org/network/284812.O13622ATP-dependent RNA helicase mss116, mitochondrial; ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns. Also required for efficient mitochondrial translation ( [...]
aim22 protein networkhttps://string-db.org/network/284812.O13629Putative lipoate-protein ligase A; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of li [...]
SPBC17A3.06 protein networkhttps://string-db.org/network/284812.O13632Tyrosine-protein phosphatase yvh1; May be directly involved in signal transduction and/or cell cycle regulation. It is necessary for maintaining growth rate or spore germination. Could show both [...]
SPBC17A3.05c protein networkhttps://string-db.org/network/284812.O13633Uncharacterized J domain-containing protein C17A3.05c.
tim50 protein networkhttps://string-db.org/network/284812.O13636Mitochondrial import inner membrane translocase subunit tim50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across th [...]
sec31 protein networkhttps://string-db.org/network/284812.O13637Protein transport protein sec31; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main fun [...]
SPBC8D2.18c protein networkhttps://string-db.org/network/284812.O13639Adenosylhomocysteinase; Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in [...]
gmh4 protein networkhttps://string-db.org/network/284812.O13640Uncharacterized alpha-1,2-galactosyltransferase C8D2.17.
SPBC8D2.16c protein networkhttps://string-db.org/network/284812.O13641Putative methyltransferase SPBC8D2.16c.
lip5 protein networkhttps://string-db.org/network/284812.O13642Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent [...]
sed5 protein networkhttps://string-db.org/network/284812.O13644Integral membrane protein sed5; Required for vesicular transport between the endoplasmic reticulum and the Golgi complex. Acts as a target organelle soluble NSF attachment protein receptor (t-SNA [...]
rmt3 protein networkhttps://string-db.org/network/284812.O13648Ribosomal protein arginine N-methyltransferase rmt3; Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in ribosomal protein rps2. Belongs to the class I-l [...]
sfc9 protein networkhttps://string-db.org/network/284812.O13650Putative transcription factor tau subunit sfc9.
irs1 protein networkhttps://string-db.org/network/284812.O13651Isoleucine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
sfi1 protein networkhttps://string-db.org/network/284812.O13652Protein sfi1; Component of the spindle pole body (SPB) half-bridge involved in the initial steps of SPB duplication; Belongs to the SFI1 family.
tom40 protein networkhttps://string-db.org/network/284812.O13656Probable mitochondrial import receptor subunit tom40; Channel-forming protein essential for import of protein precursors into mitochondria.
SPBC27B12.12c protein networkhttps://string-db.org/network/284812.O13657Putative metal ion transporter C27B12.12c.
pho7 protein networkhttps://string-db.org/network/284812.O13658Uncharacterized transcriptional regulatory protein C27B12.11c.
flx1 protein networkhttps://string-db.org/network/284812.O13660Uncharacterized mitochondrial carrier C27B12.09c.
gpi13 protein networkhttps://string-db.org/network/284812.O13663GPI ethanolamine phosphate transferase 3; Involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the [...]
far11 protein networkhttps://string-db.org/network/284812.O13665Factor arrest protein 11; Participates in the control of the reentry into the cell cycle following pheromone treatment; Belongs to the FAR11 family.
erg32 protein networkhttps://string-db.org/network/284812.O13666Delta(7)-sterol 5(6)-desaturase erg32; Catalyzes the introduction of a C-5 double bond in the B ring of ergosterol. Involved in the biosynthesis or ergosterol which is important for plasma membra [...]
ips1 protein networkhttps://string-db.org/network/284812.O13670Protein MTO1 homolog, mitochondrial; Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. Belongs to the MnmG family.
kap109 protein networkhttps://string-db.org/network/284812.O13671Importin-alpha re-exporter; Export receptor for importin alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm [...]
rpl8 protein networkhttps://string-db.org/network/284812.O1367260S ribosomal protein L8; Belongs to the eukaryotic ribosomal protein eL8 family.
mug24 protein networkhttps://string-db.org/network/284812.O13674Meiotically up-regulated gene 24 protein; Has a role in meiosis.
SPCC737.05 protein networkhttps://string-db.org/network/284812.O13679Uncharacterized protein C737.05.
ima1 protein networkhttps://string-db.org/network/284812.O13681Integral inner nuclear membrane protein ima1; Inner nuclear membrane protein that specifically binds to heterochromatic regions and promotes the tethering of centromeric DNA to the SUN-KASH compl [...]
swr1 protein networkhttps://string-db.org/network/284812.O13682Helicase swr1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by [...]
ync13 protein networkhttps://string-db.org/network/284812.O13683Uncharacterized protein C11E3.02c.
csm1 protein networkhttps://string-db.org/network/284812.O13684Monopolin complex subunit pcs1; The monopolin-like pcs1/mde4 complex is essential for accurate chromosome segregation during mitosis and meiosis II. May clamp together microtubule binding sites o [...]
ubc13 protein networkhttps://string-db.org/network/284812.O13685Ubiquitin-conjugating enzyme E2 13; Has a role in the DNA error-free postreplication repair (PRR) pathway. The ubc13/spm2 heterodimer catalyzes the synthesis of non- canonical poly-ubiquitin chai [...]
sea3 protein networkhttps://string-db.org/network/284812.O13686Uncharacterized RWD, RING finger and WD repeat-containing protein C11E3.05; May be involved in telomere capping.
vma4 protein networkhttps://string-db.org/network/284812.O13687V-type proton ATPase subunit E; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracell [...]
nse6 protein networkhttps://string-db.org/network/284812.O13688Non-structural maintenance of chromosome element 6; Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of i [...]
syt22 protein networkhttps://string-db.org/network/284812.O13690PH and SEC7 domain-containing protein C11E3.11c.
SPAC11E3.12 protein networkhttps://string-db.org/network/284812.O13691NADH-ubiquinone oxidoreductase 24 kDa subunit homolog C11E3.12, mitochondrial; Belongs to the complex I 24 kDa subunit family.
gas5 protein networkhttps://string-db.org/network/284812.O136921,3-beta-glucanosyltransferase gas5; Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan mol [...]
mtl2 protein networkhttps://string-db.org/network/284812.O13695Uncharacterized serine-rich protein C11G7.01.
idh1 protein networkhttps://string-db.org/network/284812.O13696Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle. Also binds RNA; specifically to the 5'-untranslated leaders [...]
mct1 protein networkhttps://string-db.org/network/284812.O13698Malonyl CoA-acyl carrier protein transacylase, mitochondrial; Involved in biosynthesis of fatty acids in mitochondria. Belongs to the FabD family.
taf7 protein networkhttps://string-db.org/network/284812.O13701Transcription initiation factor TFIID subunit 7; TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcription. A [...]
gld1 protein networkhttps://string-db.org/network/284812.O13702Glycerol dehydrogenase 1; Glycerol dehydrogenase involved in the assimilation of glycerol; Belongs to the iron-containing alcohol dehydrogenase family.
vta1 protein networkhttps://string-db.org/network/284812.O13703Vacuolar protein sorting-associated protein vts1; Has a role in the formation of the multivesicular body (MVB). Required for the sorting of lipids to form intralumenal vesicles and for fluid-phas [...]
mpd1 protein networkhttps://string-db.org/network/284812.O13704Thioredoxin domain-containing protein C13F5.05, mitochondrial.
sec10 protein networkhttps://string-db.org/network/284812.O13705Exocyst complex component sec10; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane; Belongs to the SEC10 family.
hpz2 protein networkhttps://string-db.org/network/284812.O13706PARP-type zinc finger-containing protein C13F5.07c.
atg43 protein networkhttps://string-db.org/network/284812.O13709Uncharacterized protein C14C4.01c.
smc5 protein networkhttps://string-db.org/network/284812.O13710Structural maintenance of chromosomes protein 5; Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ioni [...]
SPAC14C4.04 protein networkhttps://string-db.org/network/284812.O13711Uncharacterized protein C14C4.04; To S.pombe SpAC18G6.12c.
man1 protein networkhttps://string-db.org/network/284812.O13712Meiotically up-regulated gene 61 protein; Required for correct meiotic chromosome segregation.
nab2 protein networkhttps://string-db.org/network/284812.O13713Nuclear polyadenylated RNA-binding protein nab2; Binds to polyadenylated RNA and single-stranded DNA. It may be involved not only in RNA processing but also in transcription regulation. Believed [...]
SPAC14C4.07 protein networkhttps://string-db.org/network/284812.O13714Uncharacterized membrane protein C14C4.07.
mug5 protein networkhttps://string-db.org/network/284812.O13715Meiotically up-regulated gene 5 protein; Required for correct meiotic chromosome segregation.
agn1 protein networkhttps://string-db.org/network/284812.O13716Glucan endo-1,3-alpha-glucosidase agn1; Has a role in cell separation where it is required for the degradation of the cell wall material surrounding the septum (the septum edging) which must be h [...]
SPAC14C4.10c protein networkhttps://string-db.org/network/284812.O13717Uncharacterized protein C14C4.10c.
vtc2 protein networkhttps://string-db.org/network/284812.O13718Vacuolar transporter chaperone 2; Component of the vacuolar transporter chaperone (VTC) complex, which plays a role in vacuolar membrane fusion.
laf1 protein networkhttps://string-db.org/network/284812.O13719SWIRM domain-containing protein laf1; Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones [...]
taf12 protein networkhttps://string-db.org/network/284812.O13722Transcription initiation factor TFIID subunit 12; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) [...]
zpr1 protein networkhttps://string-db.org/network/284812.O13724Zinc finger protein zpr1.
mug182 protein networkhttps://string-db.org/network/284812.O13725NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisi [...]
SPAC15A10.06 protein networkhttps://string-db.org/network/284812.O13726Uncharacterized Na(+)/H(+) antiporter C15A10.06.
ain1 protein networkhttps://string-db.org/network/284812.O13728Alpha-actinin-like protein 1; Binds to actin and is involved in actin-ring formation and organization. Plays a role in cytokinesis and is involved in septation. Belongs to the alpha-actinin famil [...]
pun1 protein networkhttps://string-db.org/network/284812.O13729SUR7 family protein pun1; Contributes to the wild-type cellular response to nitrogen stress through signaling pathways that regulate the expression of genes involved in amino acid biosynthesis. R [...]
mde6 protein networkhttps://string-db.org/network/284812.O13730Mei4-dependent protein 6.
ubr11 protein networkhttps://string-db.org/network/284812.O13731E3 ubiquitin-protein ligase ubr11; Belongs to the UBR1 family.
tca17 protein networkhttps://string-db.org/network/284812.O13732Uncharacterized protein C15A10.12c.
ppk3 protein networkhttps://string-db.org/network/284812.O13733Protein kinase domain-containing protein ppk3.
sgo2 protein networkhttps://string-db.org/network/284812.O13734Shugoshin-2; Involved in chromosome cohesion during mitosis and meiosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex disso [...]
bud6 protein networkhttps://string-db.org/network/284812.O13735Actin-interacting protein 3 homolog; Involved in the organization and/or function of the actin cytoskeleton; To yeast BUD6.
shd1 protein networkhttps://string-db.org/network/284812.O13736Actin cytoskeleton-regulatory complex protein sla1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The [...]
mpo1 protein networkhttps://string-db.org/network/284812.O13737Uncharacterized endoplasmic reticulum membrane protein C16E8.02.
gna1 protein networkhttps://string-db.org/network/284812.O13738Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily.
aro7 protein networkhttps://string-db.org/network/284812.O13739Probable chorismate mutase.
nop12 protein networkhttps://string-db.org/network/284812.O13741Nucleolar protein 12; Involved in pre-25S rRNA processing; Belongs to the RRM RBM34 family.
vph1 protein networkhttps://string-db.org/network/284812.O13742V-type proton ATPase subunit a; Subunit of the integral membrane V0 complex of vacuolar ATPase essential for assembly and catalytic activity. V-ATPase is responsible for acidifying a variety of i [...]
pos1 protein networkhttps://string-db.org/network/284812.O13743Uncharacterized protein C16E8.08.
rsm7 protein networkhttps://string-db.org/network/284812.O1374437S ribosomal protein S7, mitochondrial.
tfb1 protein networkhttps://string-db.org/network/284812.O13745General transcription and DNA repair factor IIH subunit tfb1; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription [...]
SPAC16E8.13 protein networkhttps://string-db.org/network/284812.O13747RING finger protein ETP1 homolog; May act as a cytoplasmic retention protein with a role in regulating nuclear transport.
tae1 protein networkhttps://string-db.org/network/284812.O13748Alpha N-terminal protein methyltransferase 1; Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator [...]
sua7 protein networkhttps://string-db.org/network/284812.O13749Transcription initiation factor IIB; General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
SPAC16E8.17c protein networkhttps://string-db.org/network/284812.O13750Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP [...]
tlc4 protein networkhttps://string-db.org/network/284812.O13752Uncharacterized TLC domain-containing protein C17A2.02c.
vma6 protein networkhttps://string-db.org/network/284812.O13753V-type proton ATPase subunit d; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain atta [...]
cns1 protein networkhttps://string-db.org/network/284812.O13754Hsp70/Hsp90 co-chaperone cns1; Co-chaperone that binds to the molecular chaperones Hsp90 and Hsp70. Stimulates Hsp70 ATPase activity, but not Hsp90 ATPase activity. Involved in only a subset of H [...]
osm1 protein networkhttps://string-db.org/network/284812.O13755Fumarate reductase; Irreversibly catalyzes the reduction of fumarate to succinate; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
vps8 protein networkhttps://string-db.org/network/284812.O13756Vacuolar protein sorting-associated protein 8; Involved in the retention of proteins to the late-Golgi. Plays an integral role in the complex vacuolar protein sorting process (By similarity); Bel [...]
SPAC17A2.07c protein networkhttps://string-db.org/network/284812.O13757Meiotic chromosome segregation protein C17A2.07c; Involved in meiotic chromosome segregation.
ntr2 protein networkhttps://string-db.org/network/284812.O13758Uncharacterized protein C17A2.08c.
csx1 protein networkhttps://string-db.org/network/284812.O13759RNA-binding post-transcriptional regulator csx1; Regulates global gene expression after oxidative stress. Interacts and stabilizes atf1 and pcr1 mRNAs after oxidative stress, thus controlling the [...]
rrp1 protein networkhttps://string-db.org/network/284812.O13762Uncharacterized ATP-dependent helicase C17A2.12.
pex6 protein networkhttps://string-db.org/network/284812.O13764Peroxisomal ATPase pex6; Component of the peroxisomal protein import machinery. Together with pex1, mediates the ATP-dependent relocation and recycling of the peroxisomal targeting signal-1 (PTS1 [...]
dbr1 protein networkhttps://string-db.org/network/284812.O13765Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently deg [...]
mde10 protein networkhttps://string-db.org/network/284812.O13766Zinc metalloprotease mde10; Has a role in the development of the spore envelope.
ptr8 protein networkhttps://string-db.org/network/284812.O13768General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, whic [...]
ulp2 protein networkhttps://string-db.org/network/284812.O13769Ubiquitin-like-specific protease 2.
erp2 protein networkhttps://string-db.org/network/284812.O13770Uncharacterized membrane protein C17A5.08.
glc8 protein networkhttps://string-db.org/network/284812.O13771Uncharacterized protein C17A5.09c.
hua1 protein networkhttps://string-db.org/network/284812.O13772Proline/serine-rich protein C17A5.10; May be involved in assembly and disassembly of the actin cytoskeleton.
ucp7 protein networkhttps://string-db.org/network/284812.O13773UBA domain-containing protein 7.
fol2 protein networkhttps://string-db.org/network/284812.O13774GTP cyclohydrolase 1; GTP cyclohydrolase 1 is the first enzyme in the biosynthetic pathway leading to folic acid.
gus1 protein networkhttps://string-db.org/network/284812.O13775Probable glutamate--tRNA ligase, cytoplasmic; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred [...]
ftp105 protein networkhttps://string-db.org/network/284812.O13776Ubp5-interacting protein ftp105; Required for the localization of ubp5 to the Golgi apparatus. Involved in detoxification of cadmium ion.
saf5 protein networkhttps://string-db.org/network/284812.O13777Uncharacterized protein C1610.01.
mnr2 protein networkhttps://string-db.org/network/284812.O13779Putative metal ion transporter C17A12.14; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
tco1 protein networkhttps://string-db.org/network/284812.O13780Uncharacterized protein C17G6.02c.
SPAC17G6.03 protein networkhttps://string-db.org/network/284812.O13781Uncharacterized protein C17G6.03; Belongs to the 5'-nucleotidase family.
cpp1 protein networkhttps://string-db.org/network/284812.O13782Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The b [...]
bro1 protein networkhttps://string-db.org/network/284812.O13783Vacuolar protein-sorting protein bro1; Involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles; Belongs to the BRO1 f [...]
rps2401 protein networkhttps://string-db.org/network/284812.O1378440S ribosomal protein S24-A.
use1 protein networkhttps://string-db.org/network/284812.O13785Protein transport protein use1; SNARE required for targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
pep7 protein networkhttps://string-db.org/network/284812.O13786Vacuolar segregation protein pep7; Required for vacuole segregation and vacuole protein sorting. Possibly part of a complex which tethers the vacuole membrane to microtubules, either directly or [...]
sec62 protein networkhttps://string-db.org/network/284812.O13787Translocation protein sec62; Acts as component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions to [...]
ssr1 protein networkhttps://string-db.org/network/284812.O13788SWI/SNF and RSC complexes subunit ssr1; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particula [...]
SPAC17G6.11c protein networkhttps://string-db.org/network/284812.O13789Uncharacterized beta-glucan synthesis-associated protein C17G6.11c; Required for synthesis of the major beta-glucans of the yeast cell wall; Belongs to the SKN1/KRE6 family.
cul1 protein networkhttps://string-db.org/network/284812.O13790Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. The functional sp [...]
slt1 protein networkhttps://string-db.org/network/284812.O13791Protein slt1.
uap56 protein networkhttps://string-db.org/network/284812.O13792ATP-dependent RNA helicase uap56; ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 plays also a role in pre-mRNA splicing [...]
fsf1 protein networkhttps://string-db.org/network/284812.O13793Sideroflexin fsf1; Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria; Belongs to the sideroflexin family.
ysh1 protein networkhttps://string-db.org/network/284812.O13794Endoribonuclease ysh1; Component of the cleavage factor I (CF I) involved in pre- mRNA 3'-end processing; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactama [...]
pof8 protein networkhttps://string-db.org/network/284812.O13795Protein pof8.
rqc1 protein networkhttps://string-db.org/network/284812.O13796Ribosome quality control complex subunit 1; Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synt [...]
sgt2 protein networkhttps://string-db.org/network/284812.O13797Small glutamine-rich tetratricopeptide repeat-containing protein 2; Co-chaperone that binds to the molecular chaperone Hsp70 and regulates Hsp70 ATPase activity; Belongs to the SGT family.
cid16 protein networkhttps://string-db.org/network/284812.O13798Caffeine-induced protein 16.
mtl1 protein networkhttps://string-db.org/network/284812.O13799Uncharacterized helicase C17H9.02; Belongs to the helicase family. SKI2 subfamily.
rdl1 protein networkhttps://string-db.org/network/284812.O13800DNA repair protein rdl1; Involved in homologous recombination where it functions at an early stage of recombination in a pre-recombinogenic complex with rlp1 and sws1. Also has a role at a later [...]
dri1 protein networkhttps://string-db.org/network/284812.O13801Uncharacterized RNA-binding protein C17H9.04c.
ebp2 protein networkhttps://string-db.org/network/284812.O13802Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA.
SPAC17H9.06c protein networkhttps://string-db.org/network/284812.O13803Uncharacterized protein C17H9.06c.
srp21 protein networkhttps://string-db.org/network/284812.O13804Uncharacterized protein C17H9.07.
SPAC17H9.08 protein networkhttps://string-db.org/network/284812.O13805Uncharacterized mitochondrial carrier C17H9.08.
ddb1 protein networkhttps://string-db.org/network/284812.O13807DNA damage-binding protein 1; Component of an E3 ubiquitin-protein ligase that includes cul4 (By similarity). Required for ubiquitination and the subsequent degradation of the DNA replication lic [...]
gmf1 protein networkhttps://string-db.org/network/284812.O13808Actin-depolymerizing factor gmf1; Actin depolymerizing factor involved in the control of the disassembly of actin patches. Binds and suppresses the arp2/3 complex functions such as the promotion [...]
cyc2 protein networkhttps://string-db.org/network/284812.O13809Uncharacterized FAD-binding protein C17H9.12c; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
pro2 protein networkhttps://string-db.org/network/284812.O13810Probable glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline.
pdi2 protein networkhttps://string-db.org/network/284812.O13811Protein disulfide-isomerase C17H9.14c; Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer; Belong [...]
tom22 protein networkhttps://string-db.org/network/284812.O13813Mitochondrial import receptor subunit tom22; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. To [...]
mdm10 protein networkhttps://string-db.org/network/284812.O13814Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of t [...]
SPAC17H9.18c protein networkhttps://string-db.org/network/284812.O13815Meiotically up-regulated gene 52 protein; Has a role in meiosis.
psc3 protein networkhttps://string-db.org/network/284812.O13816Cohesin subunit psc3; Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring [...]
sec73 protein networkhttps://string-db.org/network/284812.O13817Protein transport protein sec73; May play a role in protein transport.
ltc2 protein networkhttps://string-db.org/network/284812.O13818Uncharacterized PH domain-containing protein C19A8.02.
ymr1 protein networkhttps://string-db.org/network/284812.O13819Phosphoinositide 3-phosphatase; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P). Involved in the control of PI3P-dependent signaling and in the maintenance of [...]
erg5 protein networkhttps://string-db.org/network/284812.O13820Cytochrome P450 61; Required to form the C-22(23) double bond in the sterol side chain; Belongs to the cytochrome P450 family.
sst4 protein networkhttps://string-db.org/network/284812.O13821Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT [...]
pbr1 protein networkhttps://string-db.org/network/284812.O13822Uncharacterized oxidoreductase C19A8.06.
imp4 protein networkhttps://string-db.org/network/284812.O13823U3 small nucleolar ribonucleoprotein protein imp4; Component of the U3 small nucleolar ribonucleoprotein. Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA proc [...]
upf2 protein networkhttps://string-db.org/network/284812.O13824Nonsense-mediated mRNA decay protein 2; Involved in nonsense-mediated decay of mRNAs containing premature stop codons. It interacts, via its C-terminus, with NAM7/UPF1. Could be involved in deter [...]
yos1 protein networkhttps://string-db.org/network/284812.O13825Protein transport protein yos1; Required for protein transport between endoplasmic reticulum and Golgi apparatus.
rfp1 protein networkhttps://string-db.org/network/284812.O13826E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp1; Mediates ubiquitination and subsequent desumoylation/degradation of sumoylated proteins and proteins containing SUMO-like domains. Invol [...]
irc6 protein networkhttps://string-db.org/network/284812.O13827Uncharacterized protein C19A8.11c.
dcp2 protein networkhttps://string-db.org/network/284812.O13828mRNA decapping complex subunit 2; Catalytic component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense- mediated mRNA decay. Removes t [...]
usp101 protein networkhttps://string-db.org/network/284812.O13829U1 small nuclear ribonucleoprotein 70 kDa homolog; Involved in nuclear mRNA splicing (By similarity). Essential for growth.
pth2 protein networkhttps://string-db.org/network/284812.O13830Probable peptidyl-tRNA hydrolase 2; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis; Belongs to the PTH2 family.
trp2 protein networkhttps://string-db.org/network/284812.O13831Tryptophan synthase; In the C-terminal section; belongs to the TrpB family.
cid1 protein networkhttps://string-db.org/network/284812.O13833Terminal uridylyltransferase cid1; Cytoplasmic uridylyltransferase that mediates the terminal uridylation of mRNAs with short poly(A) tails such as such as act1, hcn1 and urg1 mRNAs, hence facili [...]
ptr1 protein networkhttps://string-db.org/network/284812.O13834E3 ubiquitin-protein ligase ptr1; Probable ubiquitin ligase protein involved in mRNA export. E3 ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target p [...]
imp3 protein networkhttps://string-db.org/network/284812.O13835U3 small nucleolar ribonucleoprotein protein imp3; Component of the U3 small nucleolar ribonucleoprotein. Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA proc [...]
din1 protein networkhttps://string-db.org/network/284812.O13836Decapping nuclease din1; Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping and pyrophosphohydrolase ac [...]
uga1 protein networkhttps://string-db.org/network/284812.O138374-aminobutyrate aminotransferase; Required for the degradation of gamma-aminobutyric acid (GABA), which is important for utilization of GABA as nitrogen source. Deaminates GABA to succinate-semia [...]
nup40 protein networkhttps://string-db.org/network/284812.O13838Nucleoporin nup40; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components [...]
fin1 protein networkhttps://string-db.org/network/284812.O13839G2-specific protein kinase fin1; Promotes chromosome condensation and nuclear envelope dynamics during mitosis. Activity appears at metaphase-anaphase transition; Belongs to the protein kinase su [...]
cda1 protein networkhttps://string-db.org/network/284812.O13842Chitin deacetylase 1; Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin. Required for proper spore formation. Belongs to the polysaccharide deacetylase family.
dal1 protein networkhttps://string-db.org/network/284812.O13843Ureidoglycolate lyase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as secondar [...]
mce1 protein networkhttps://string-db.org/network/284812.O13844Uncharacterized mitochondrial carrier C19G12.05.
rsd1 protein networkhttps://string-db.org/network/284812.O13845RNA-binding protein rsd1.
scs7 protein networkhttps://string-db.org/network/284812.O13846Ceramide very long chain fatty acid hydroxylase scs7; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very [...]
SPAC19G12.09 protein networkhttps://string-db.org/network/284812.O13848NAD/NADP-dependent indole-3-acetaldehyde reductase.
cpy1 protein networkhttps://string-db.org/network/284812.O13849Carboxypeptidase Y; Involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or ph [...]
coq9 protein networkhttps://string-db.org/network/284812.O13850Ubiquinone biosynthesis protein coq9, mitochondrial; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for a [...]
dlp1 protein networkhttps://string-db.org/network/284812.O13851Decaprenyl-diphosphate synthase subunit 2; Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10.
poz1 protein networkhttps://string-db.org/network/284812.O13852Protection of telomeres protein poz1; Telomeric DNA-binding protein that negatively regulates telomerase and telomere length.
its3 protein networkhttps://string-db.org/network/284812.O13853Phosphatidylinositol 4-phosphate 5-kinase its3; Involved, together with the calcineurin ppb1, in cytokinesis.
adg2 protein networkhttps://string-db.org/network/284812.O13854Serine/threonine-rich protein adg2.
SPAC1A6.01c protein networkhttps://string-db.org/network/284812.O13855Uncharacterized protein C1A6.01c.
wdr55 protein networkhttps://string-db.org/network/284812.O13856Uncharacterized WD repeat-containing protein C1A6.02.
plb3 protein networkhttps://string-db.org/network/284812.O13857Putative lysophospholipase SPAC1A6.03c; Catalyzes the release of fatty acids from lysophospholipids. Belongs to the lysophospholipase family.
sle1 protein networkhttps://string-db.org/network/284812.O13858Eisosome protein sle1; Important for the biogenesis of filamentous eisosomes, large cytoplasmic protein assemblies that localize to specialized domains on the plasma membrane to cluster specific [...]
tcd1 protein networkhttps://string-db.org/network/284812.O13861tRNA threonylcarbamoyladenosine dehydratase; Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read co [...]
deb1 protein networkhttps://string-db.org/network/284812.O13862Transcriptional activator protein rdp1; Acts as a DNA damage-response activator of rhp51. Binds to part of the DNA damage-responsive element (DRE), (5'-NG[GT]T[GA]-3').
SPAC1B1.02c protein networkhttps://string-db.org/network/284812.O13863Uncharacterized kinase C1B1.02c; Belongs to the NAD kinase family.
kap95 protein networkhttps://string-db.org/network/284812.O13864Importin subunit beta-1; Importin beta subunit that functions in nuclear protein import through association with the importin alpha subunit, which binds to the clasical nuclear localization signa [...]
pan3 protein networkhttps://string-db.org/network/284812.O13865PAB-dependent poly(A)-specific ribonuclease subunit pan3-like; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex; Belongs to the protein kinase superfamily. PAN3 family.
SPAC1B3.01c protein networkhttps://string-db.org/network/284812.O13867Uracil phosphoribosyltransferase 1; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
SPAC1B3.02c protein networkhttps://string-db.org/network/284812.O13868Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family [...]
guf1 protein networkhttps://string-db.org/network/284812.O13869Translation factor guf1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRN [...]
not3 protein networkhttps://string-db.org/network/284812.O13870General negative regulator of transcription subunit 3; Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the ma [...]
SPAC1B3.06c protein networkhttps://string-db.org/network/284812.O13871Uncharacterized methyltransferase C1B3.06c; Probable methyltransferase.
vps28 protein networkhttps://string-db.org/network/284812.O13872Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex, a regulator of vesicular trafficking process.
SPAC1B3.08 protein networkhttps://string-db.org/network/284812.O13873Protein CSN12 homolog; Belongs to the CSN12 family.
noc202 protein networkhttps://string-db.org/network/284812.O13874Uncharacterized NOC2 family protein C1B3.09c.
hrd302 protein networkhttps://string-db.org/network/284812.O13875Uncharacterized Sel1-like repeat-containing protein C1B3.10c; Belongs to the sel-1 family.
ypt4 protein networkhttps://string-db.org/network/284812.O13876GTP-binding protein ypt4.
rpb10 protein networkhttps://string-db.org/network/284812.O13877DNA-directed RNA polymerases I, II, and III subunit RPABC5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Com [...]
nan1 protein networkhttps://string-db.org/network/284812.O13878U3 small nucleolar RNA-associated protein 17; Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a s [...]
SPAC1B3.15c protein networkhttps://string-db.org/network/284812.O13879Uncharacterized transporter C1B3.15C.
vht1 protein networkhttps://string-db.org/network/284812.O13880Vitamin H transporter 1; Involved in uptake of biotin and desthiobiotin with the concomitant entry of protons; Belongs to the major facilitator superfamily. Allantoate permease family.
clr2 protein networkhttps://string-db.org/network/284812.O13881Cryptic loci regulator 2; Required for deacetylation in the mating-type region and the centromere. Acts upstream of the histone deacetylases to promote transcriptional silencing. Required for pro [...]
mrps18 protein networkhttps://string-db.org/network/284812.O13882Putative 37S ribosomal protein S18, mitochondrial; Belongs to the universal ribosomal protein uS11 family.
gab1 protein networkhttps://string-db.org/network/284812.O13883GPI transamidase component GAB1 homolog; Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI (By similari [...]
SPAC1E11.02 protein networkhttps://string-db.org/network/284812.O13886Uncharacterized protein C823.02.
hri1 protein networkhttps://string-db.org/network/284812.O13889Eukaryotic translation initiation factor 2-alpha kinase 1; Mediates down-regulation of protein synthesis in response to stress conditions by the phosphorylation of the alpha subunit of eIF-2 (tif [...]
fmp40 protein networkhttps://string-db.org/network/284812.O13890Protein adenylyltransferase SelO, mitochondrial; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Tyr residues of target mitochondrial proteins (AMPylation). Involved in redox homeos [...]
pdc1 protein networkhttps://string-db.org/network/284812.O13892Uncharacterized protein C20G4.08.
mug103 protein networkhttps://string-db.org/network/284812.O13894Meiotically up-regulated gene 103 protein; Has a role in meiosis.
csn4 protein networkhttps://string-db.org/network/284812.O13895COP9 signalosome complex subunit 4; Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cull [...]
rpc11 protein networkhttps://string-db.org/network/284812.O13896DNA-directed RNA polymerase III subunit RPC10; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA [...]
fsh2 protein networkhttps://string-db.org/network/284812.O13897Uncharacterized hydrolase C22A12.06c.
ogm1 protein networkhttps://string-db.org/network/284812.O13898Dolichyl-phosphate-mannose--protein mannosyltransferase 1; Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. Required for normal cell growth and septum formation. Shown to [...]
crd1 protein networkhttps://string-db.org/network/284812.O13899Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein C22A12.08c.
sap114 protein networkhttps://string-db.org/network/284812.O13900Pre-mRNA-splicing factor sap114; Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures [...]
ept1 protein networkhttps://string-db.org/network/284812.O13901Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein C22A12.10.
dak1 protein networkhttps://string-db.org/network/284812.O13902Dihydroxyacetone kinase 1; Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde; Belongs to the dihydroxyacetone kinase (DAK) family.
rrp40 protein networkhttps://string-db.org/network/284812.O13903Exosome complex component rrp40; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrad [...]
mug84 protein networkhttps://string-db.org/network/284812.O13904Meiotically up-regulated gene 84 protein; Has a role in meiosis.
SPAC22A12.14c protein networkhttps://string-db.org/network/284812.O13905BSD domain-containing protein C22A12.14c.
acl2 protein networkhttps://string-db.org/network/284812.O13907Probable ATP-citrate synthase subunit 2; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA. Has a central role in de novo lipid synthesis (By similarit [...]
SPAC22A12.17c protein networkhttps://string-db.org/network/284812.O13908Uncharacterized oxidoreductase C22A12.17c.
ice2 protein networkhttps://string-db.org/network/284812.O13909Uncharacterized protein C23C11.01.
mpp10 protein networkhttps://string-db.org/network/284812.O13910U3 small nucleolar ribonucleoprotein protein mpp10; Component of the U3 small nucleolar ribonucleoprotein. Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA pro [...]
pnk1 protein networkhttps://string-db.org/network/284812.O13911Bifunctional polynucleotide phosphatase/kinase; Catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini. Has a role in the repair of breaks in [...]
SPAC23C11.06c protein networkhttps://string-db.org/network/284812.O13912Uncharacterized protein C23C11.06c.
ala1 protein networkhttps://string-db.org/network/284812.O13914Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA( [...]
mpn1 protein networkhttps://string-db.org/network/284812.O13915U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides [...]
hcn1 protein networkhttps://string-db.org/network/284812.O13916Anaphase-promoting complex subunit hcn1; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression throug [...]
hpt1 protein networkhttps://string-db.org/network/284812.O13917Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosyl [...]
zhf1 protein networkhttps://string-db.org/network/284812.O13918Zinc homeostasis factor 1; Involved in zinc homeostasis, where it plays a role in its accumulation in the endoplasmic reticulum/nucleus. Also has a role in the sequestration of cadmium into the e [...]
pst2 protein networkhttps://string-db.org/network/284812.O13919Paired amphipathic helix protein pst2; Has a role in chromatin assembly and chromosome segregation. Involved in the deacetylation of histones.
mdm28 protein networkhttps://string-db.org/network/284812.O13920LETM1 domain-containing protein mdm28, mitochondrial; Involved in mitochondrial potassium homeostasis through the mitochondrial K(+)/H(+) exchange regulation.
msh1 protein networkhttps://string-db.org/network/284812.O13921MutS protein homolog 1; Involved in mitochondrial DNA repair; Belongs to the DNA mismatch repair MutS family.
crn1 protein networkhttps://string-db.org/network/284812.O13923Coronin-like protein crn1.
hrk1 protein networkhttps://string-db.org/network/284812.O13924Serine/threonine-protein kinase haspin homolog hrk1; Serine/threonine haspin-like protein kinase involved in cell cycle regulation. Acts in chromosomal passenger complex (CPC) targeting to centro [...]
efm6 protein networkhttps://string-db.org/network/284812.O13926UPF0665 family protein C23C4.06c.
tht2 protein networkhttps://string-db.org/network/284812.O13927Twin horsetail protein 2; Required for correct meiotic chromosome segregation and recombination.
rho3 protein networkhttps://string-db.org/network/284812.O13928GTP-binding protein rho3; Involved in controlling cell shape and septation. Regulates cell separation by modulating the function of the exocyst complex. Involved in post-Golgi vesicle transport.
SPAC23C4.09c protein networkhttps://string-db.org/network/284812.O13929Uncharacterized protein C23C4.09c; Belongs to the PDCD5 family.
sec2 protein networkhttps://string-db.org/network/284812.O13930Rab guanine nucleotide exchange factor sec2; Guanyl-nucleotide exchange factor for ypt2. Catalyzing the dissociation of GDP from ypt2 and promotes the binding of GTP (By similarity).
atp18 protein networkhttps://string-db.org/network/284812.O13931ATP synthase subunit J, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
bet1 protein networkhttps://string-db.org/network/284812.O13932Protein transport protein bet1; SNARE required for targeting and fusion of ER-derived transport vesicles with the Golgi complex.
alg1 protein networkhttps://string-db.org/network/284812.O13933Chitobiosyldiphosphodolichol beta-mannosyltransferase; Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyropho [...]
atg15 protein networkhttps://string-db.org/network/284812.O13934Putative lipase atg15; Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multives [...]
trm402 protein networkhttps://string-db.org/network/284812.O13935Multisite-specific tRNA:(cytosine-C(5))-methyltransferase trm4b; tRNA cytosine C(5)-methyltransferase that methylates cytosine to 5-methylcytosine (m5C) in tRNAs at position 49 and 50. Trm4a and [...]
spt5 protein networkhttps://string-db.org/network/284812.O13936Transcription elongation factor spt5; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be [...]
SPAC23H3.04 protein networkhttps://string-db.org/network/284812.O13938UPF0658 Golgi apparatus membrane protein C23H3.04.
apl6 protein networkhttps://string-db.org/network/284812.O13939AP-3 complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact wit [...]
gly1 protein networkhttps://string-db.org/network/284812.O13940Probable low-specificity L-threonine aldolase.
SPAC23H3.11c protein networkhttps://string-db.org/network/284812.O13941Uncharacterized beta-glucan synthesis-associated protein C23H3.11c; Required for synthesis of the major beta-glucans of the yeast cell wall; Belongs to the SKN1/KRE6 family.
avl9 protein networkhttps://string-db.org/network/284812.O13943Late secretory pathway protein avl9; Functions in the late secretory pathway. Required for the generation of secretory vesicles as well as for actin polarization and polarized growth (By similari [...]
osh3 protein networkhttps://string-db.org/network/284812.O13944Oxysterol-binding protein homolog C23H4.01c.
ppk9 protein networkhttps://string-db.org/network/284812.O13945Protein kinase domain-containing protein ppk9.
erv25 protein networkhttps://string-db.org/network/284812.O13946Endoplasmic reticulum vesicle protein 25; Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the G [...]
slm3 protein networkhttps://string-db.org/network/284812.O13947Mitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation o [...]
SPAC23H4.05c protein networkhttps://string-db.org/network/284812.O13948Uncharacterized protein C23H4.05c.
srp102 protein networkhttps://string-db.org/network/284812.O13950Signal recognition particle receptor subunit beta; Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting [...]
iwr1 protein networkhttps://string-db.org/network/284812.O13951RNA polymerase II nuclear localization protein iwr1; Directs RNA polymerase II nuclear import.
cnl2 protein networkhttps://string-db.org/network/284812.O13952Inner kinetochore subunit cnl2; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segre [...]
alp13 protein networkhttps://string-db.org/network/284812.O13953Chromatin modification-related protein eaf3; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation o [...]
vam6 protein networkhttps://string-db.org/network/284812.O13955Vacuolar morphogenesis protein 6; Required for vacuolar assembly. Acts as component of the HOPS complex that acts during the docking stage of vacuole fusion. HOPS is required for vacuolar SNARE c [...]
tsr1 protein networkhttps://string-db.org/network/284812.O13956Ribosome biogenesis protein tsr1; Required for 40S ribosomal subunit synthesis. Required for normal export of the pre-40S particles from the nucleus to the cytoplasm (By similarity); Belongs to t [...]
not11 protein networkhttps://string-db.org/network/284812.O13957Uncharacterized protein C23H4.16c.
srb10 protein networkhttps://string-db.org/network/284812.O13958Serine/threonine-protein kinase srb10; Catalytic component of the Cdk8 module/Srb8-11 module which is a regulatory module of the Mediator complex that regulates basal RNA polymerase II transcript [...]
rbx1 protein networkhttps://string-db.org/network/284812.O13959RING-box protein pip1; Component of E3 ubiquitin ligase SCF complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recruit the E2 ubiquiti [...]
ecm33 protein networkhttps://string-db.org/network/284812.O13960Cell wall protein ecm33; Involved in the negative feedback regulation of pmk1 cell integrity signaling and is linked to cellular calcium signaling.
cut11 protein networkhttps://string-db.org/network/284812.O13961Nuclear envelope protein ndc1; Component of the nuclear pore complex (NPC) and the spindle pole body (SPB), which plays a key role in de novo assembly and insertion of both structures in the nucl [...]
cyt2 protein networkhttps://string-db.org/network/284812.O13962Putative cytochrome c1 heme lyase; Involved in the final maturation of cytochrome c1, it links covalently the heme group to the apoprotein.
mvd1 protein networkhttps://string-db.org/network/284812.O13963Diphosphomevalonate decarboxylase.
SPAC24C9.04 protein networkhttps://string-db.org/network/284812.O13964Uncharacterized protein C24C9.04.
mug70 protein networkhttps://string-db.org/network/284812.O13965Meiotically up-regulated gene 70 protein; Has a role in meiosis.
aco1 protein networkhttps://string-db.org/network/284812.O13966Aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate, a step in the citric acid cycle; Belongs to the aconitase/IPM isomerase family.
bgs2 protein networkhttps://string-db.org/network/284812.O139671,3-beta-glucan synthase component bgs2; Has a role in ascospore development where it is required for the assembly of a functional spore wall; Belongs to the glycosyltransferase 48 family.
cps1 protein networkhttps://string-db.org/network/284812.O13968Uncharacterized carboxypeptidase C24C9.08; Belongs to the peptidase M20A family.
SPAC24C9.09 protein networkhttps://string-db.org/network/284812.O13969Probable threonine--tRNA ligase, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family.
mrp4 protein networkhttps://string-db.org/network/284812.O1397037S ribosomal protein mrp4, mitochondrial; Belongs to the universal ribosomal protein uS2 family.
sgd1 protein networkhttps://string-db.org/network/284812.O13971Suppressor of glycerol defect protein 1; Involved in osmoregulatory glycerol response; Belongs to the CWC22 family.
shm1 protein networkhttps://string-db.org/network/284812.O13972Probable serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine; Belongs to the SHMT family.
mrp10 protein networkhttps://string-db.org/network/284812.O1397337S ribosomal protein mrp10, mitochondrial; Involved in mitochondrial genome encoded proteins translation.
otu1 protein networkhttps://string-db.org/network/284812.O13974Putative ubiquitin thioesterase otu1; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventi [...]
jmj1 protein networkhttps://string-db.org/network/284812.O13977JmjC domain-containing protein 1.
atg101 protein networkhttps://string-db.org/network/284812.O13978Meiotically up-regulated gene 66 protein; Autophagy factor required for autophagosome formation (By similarity). Has a role in meiosis and sporulation; Belongs to the ATG101 family.
mug105 protein networkhttps://string-db.org/network/284812.O13979Ubiquitin carboxyl-terminal hydrolase mug105; Deubiquitinase with endodeubiquitinase activity that preferentially cleaves 'Lys-48'-linked polyubiquitin chains. Shows only weak activity against 'L [...]
meu29 protein networkhttps://string-db.org/network/284812.O13980Meiotic expression up-regulated protein 29.
emc1 protein networkhttps://string-db.org/network/284812.O13981ER membrane protein complex subunit 1; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).
sqt1 protein networkhttps://string-db.org/network/284812.O13982Uncharacterized WD repeat-containing protein C25H1.08c.
hrq1 protein networkhttps://string-db.org/network/284812.O13983ATP-dependent helicase hrq1; Helicase with 3'-5' helicase activity involved in genome stability. Functions in the nucleotide excision repair (NER) pathway and plays a critical role in DNA interst [...]
mgs1 protein networkhttps://string-db.org/network/284812.O13984ATPase WRNIP1 homolog C26H5.02c; Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions [...]
pcf2 protein networkhttps://string-db.org/network/284812.O13985Uncharacterized WD repeat-containing protein C26H5.03.
gid5 protein networkhttps://string-db.org/network/284812.O13986Uncharacterized protein C26H5.04.
mga2 protein networkhttps://string-db.org/network/284812.O13987Ankyrin and IPT/TIG repeat-containing protein C26H5.05.
pot1 protein networkhttps://string-db.org/network/284812.O13988Protection of telomeres protein 1; Single-stranded telomeric DNA-binding protein that is required to protect the 3'-end telomeric overhang. It binds the consensus sequence 5'-GGTTAC-3'. Regulates [...]
bgl2 protein networkhttps://string-db.org/network/284812.O13990Glucan 1,3-beta-glucosidase; Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involv [...]
SPAC26H5.09c protein networkhttps://string-db.org/network/284812.O13991Uncharacterized oxidoreductase C26H5.09c; Belongs to the Gfo/Idh/MocA family.
mug56 protein networkhttps://string-db.org/network/284812.O13992Meiotically up-regulated gene 56 protein; Has a role in meiosis.
rpo41 protein networkhttps://string-db.org/network/284812.O13993DNA-directed RNA polymerase, mitochondrial; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Combines in the mit [...]
kei1 protein networkhttps://string-db.org/network/284812.O13994Inositol phosphorylceramide synthase regulatory subunit kei1; Regulatory component of the inositol phosphorylceramide (ICP) synthase which catalyzes the addition of a phosphorylinositol group ont [...]
dap1 protein networkhttps://string-db.org/network/284812.O13995Cytochrome P450 regulator dap1; Required for sterol biosynthesis. Functions as a positive regulator of cytochrome P450 enzymes erg5 and erg11. Function requires bound heme; Belongs to the cytochr [...]
SPAC27E2.01 protein networkhttps://string-db.org/network/284812.O13996Uncharacterized glycosyl hydrolase C27E2.01; Belongs to the glycosyl hydrolase 13 family.
yih1 protein networkhttps://string-db.org/network/284812.O13997Protein IMPACT homolog; Translational regulator that ensures constant high levels of translation under amino acid starvation. Plays a role as a negative regulator of the gcn2 kinase activity; imp [...]
SPAC27E2.03c protein networkhttps://string-db.org/network/284812.O13998Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP (By similarity). Negatively regulates the G2/M transition in the cell cycle; Belong [...]
msm1 protein networkhttps://string-db.org/network/284812.O14000Probable methionine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
pvg2 protein networkhttps://string-db.org/network/284812.O14001Pyruvylated Gal-beta-1,3-epitope synthesis protein 2; Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moeities to galactomannans and their subsequent pyruvylation. Has [...]
mak2 protein networkhttps://string-db.org/network/284812.O14002Peroxide stress-activated histidine kinase mak2; Involved in the control of the SAPK-dependent transcriptional response to peroxide stress. Regulates sty1 activity.
rfc3 protein networkhttps://string-db.org/network/284812.O14003Replication factor C subunit 3; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. Subunit 3 binds ATP. [...]
mrps9 protein networkhttps://string-db.org/network/284812.O1400637S ribosomal protein S9, mitochondrial.
cbf5 protein networkhttps://string-db.org/network/284812.O14007H/ACA ribonucleoprotein complex subunit cbf5; Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the iso [...]
cam2 protein networkhttps://string-db.org/network/284812.O14008Myosin 1 light chain cam2; Plays a role in meiosis and sporulation.
SPAC29A4.06c protein networkhttps://string-db.org/network/284812.O14009Nuclear speckle splicing regulatory protein 1 homolog; Belongs to the NSRP1 family.
srb6 protein networkhttps://string-db.org/network/284812.O14010Mediator of RNA polymerase II transcription subunit 22; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
prp19 protein networkhttps://string-db.org/network/284812.O14011Pre-mRNA-processing factor 19; Probable ubiquitin-protein ligase involved in pre-mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome. May also functi [...]
rrp17 protein networkhttps://string-db.org/network/284812.O14012Ribosomal RNA-processing protein 17; Involved in ribosomal RNA processing; Belongs to the RRP17 family.
rrn5 protein networkhttps://string-db.org/network/284812.O14013RNA polymerase I-specific transcription initiation factor rrn5; Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promote [...]
rga3 protein networkhttps://string-db.org/network/284812.O14014Probable Rho-type GTPase-activating protein 3; GTPase-activating protein for Rho-type proteins.
mug108 protein networkhttps://string-db.org/network/284812.O14015Meiotically up-regulated gene 108 protein; Has a role in meiosis.
ure6 protein networkhttps://string-db.org/network/284812.O14016Uncharacterized urease accessory protein UreF-like; Probably facilitates nickel incorporation; Belongs to the UreF family.
pex3 protein networkhttps://string-db.org/network/284812.O14017Uncharacterized protein C29A4.14c.
srs1 protein networkhttps://string-db.org/network/284812.O14018Serine--tRNA ligase, cytoplasmic; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will [...]
hal4 protein networkhttps://string-db.org/network/284812.O14019Serine/threonine-protein kinase hal4; Promotes K(+) uptake, by the potassium transporter trk1-trk2, which leads to the subsequent cellular resistance to toxic cations such as Na(+), Li(+) and Ca( [...]
fun14 protein networkhttps://string-db.org/network/284812.O14020Uncharacterized protein C29A4.17c.
prw1 protein networkhttps://string-db.org/network/284812.O14021RbAp48-related WD40 repeat-containing protein prw1; Has a role in chromatin assembly and chromosome segregation. Involved in the deacetylation of histones. Belongs to the WD repeat HIR1 family.
cta5 protein networkhttps://string-db.org/network/284812.O14022Cation-transporting ATPase 5; Plays a role in regulating calcium and manganese homeostasis responsible for cell cycle progression.
elp3 protein networkhttps://string-db.org/network/284812.O14023Elongator complex protein 3; Catalytic subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elo [...]
set2 protein networkhttps://string-db.org/network/284812.O14026Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3 (By similarity). Involved in transcription elongation [...]
snz1 protein networkhttps://string-db.org/network/284812.O14027Probable pyridoxal 5'-phosphate synthase subunit PDX1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia i [...]
mtq1 protein networkhttps://string-db.org/network/284812.O14028Probable MRF1 mitochondrial N(5)-glutamine methyltransferase mtq1; Methylates MRF1 on 'Gln-270' using S-adenosyl L-methionine as methyl donor.
sec16 protein networkhttps://string-db.org/network/284812.O14029COPII coat assembly protein sec16; Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection [...]
clr5 protein networkhttps://string-db.org/network/284812.O14030Uncharacterized protein C29B12.08.
pgt1 protein networkhttps://string-db.org/network/284812.O14031Glutathione transporter 1; High-affinity glutathione transporter which plays a role in scavenging glutathione from the extracellular environment for the maintenance of sulfur homeostasis; Belongs [...]
SPAC29B12.11c protein networkhttps://string-db.org/network/284812.O14032UPF0664 stress-induced protein C29B12.11c; Belongs to the UPF0664 family.
hot13 protein networkhttps://string-db.org/network/284812.O14033Uncharacterized protein C29B12.12.
SPAC29B12.14c protein networkhttps://string-db.org/network/284812.O14035Uncharacterized permease C29B12.14c.
smd2 protein networkhttps://string-db.org/network/284812.O14036Small nuclear ribonucleoprotein Sm D2; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site (By similarity).
cor1 protein networkhttps://string-db.org/network/284812.O14038Uncharacterized protein C2C4.05.
rcm1 protein networkhttps://string-db.org/network/284812.O1403925S rRNA (cytosine-C(5))-methyltransferase rcm1; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of a cytosine in 25S rRNA. Belongs to the class [...]
dis32 protein networkhttps://string-db.org/network/284812.O14040DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation [...]
SPAC2C4.08 protein networkhttps://string-db.org/network/284812.O14041Uncharacterized nucleolar protein C2C4.08.
SPAC2C4.09 protein networkhttps://string-db.org/network/284812.O14042Protein fmp32, mitochondrial.
csc4 protein networkhttps://string-db.org/network/284812.O14043Uncharacterized protein C2C4.10c.
pno1 protein networkhttps://string-db.org/network/284812.O14044Pre-rRNA-processing protein pno1; Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.
tpt1 protein networkhttps://string-db.org/network/284812.O14045Putative tRNA 2'-phosphotransferase; Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP- ribose 1''-2'' cyclic phos [...]
vma16 protein networkhttps://string-db.org/network/284812.O14046Probable V-type proton ATPase 20 kDa proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a v [...]
ppk11 protein networkhttps://string-db.org/network/284812.O14047Serine/threonine-protein kinase ppk11.
ubx2 protein networkhttps://string-db.org/network/284812.O14048UBX domain-containing protein 2; Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway.
rps801 protein networkhttps://string-db.org/network/284812.O1404940S ribosomal protein S8-A.
msy2 protein networkhttps://string-db.org/network/284812.O14050Mechanosensitive ion channel protein Msy2; Regulates intracellular calcium levels and cell volume for survival in response to hypo-osmotic shock. Involved in maintaining vacuole integrity and pro [...]
utp21 protein networkhttps://string-db.org/network/284812.O14053U3 small nucleolar RNA-associated protein 21 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
yrs1 protein networkhttps://string-db.org/network/284812.O14055Tyrosine--tRNA ligase, cytoplasmic; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the accep [...]
cox19 protein networkhttps://string-db.org/network/284812.O14056Cytochrome c oxidase assembly protein cox19, mitochondrial; Required for the assembly of mitochondrial cytochrome c oxidase; Belongs to the COX19 family.
gud1 protein networkhttps://string-db.org/network/284812.O14057Probable guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
SPCC1672.01 protein networkhttps://string-db.org/network/284812.O14059Probable histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.
ast1 protein networkhttps://string-db.org/network/284812.O14061Asteroid homolog 1.
rps1201 protein networkhttps://string-db.org/network/284812.O1406240S ribosomal protein S12-A.
cut15 protein networkhttps://string-db.org/network/284812.O14063Importin subunit alpha-1; Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. Seems to [...]
bir1 protein networkhttps://string-db.org/network/284812.O14064Protein bir1; Seems to act in the pleiotropic control of cell division. Has a role in chromosome segregation by recruiting condensin and ark1 kinase to appropriate sites as the cell progresses th [...]
tcb1 protein networkhttps://string-db.org/network/284812.O14065Uncharacterized protein C962.01.
irs4 protein networkhttps://string-db.org/network/284812.O14066Increased rDNA silencing protein 4 homolog; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in [...]
SPAC1687.07 protein networkhttps://string-db.org/network/284812.O14068UPF0357 protein C1687.07; Belongs to the UPF0357 family.
rpl44 protein networkhttps://string-db.org/network/284812.O14069Probable 60S ribosomal protein L28e; Belongs to the eukaryotic ribosomal protein eL28 family.
cta4 protein networkhttps://string-db.org/network/284812.O14072Manganese-transporting ATPase 4; Mediates manganese transport into the endoplasmic reticulum. The ATPase activity is required for cellular manganese homeostasis (By similarity). Involved in contr [...]
dpp2 protein networkhttps://string-db.org/network/284812.O14073Putative dipeptidyl aminopeptidase C2E11.08.
gor1 protein networkhttps://string-db.org/network/284812.O14075Putative 2-hydroxyacid dehydrogenase UNK4.10; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
mpp6 protein networkhttps://string-db.org/network/284812.O14076Uncharacterized protein UNK4.11c; Belongs to the MPP6 family.
iph1 protein networkhttps://string-db.org/network/284812.O14077Putative zinc protease mug138; Has a role in meiosis; Belongs to the peptidase M16 family.
SPACUNK4.13c protein networkhttps://string-db.org/network/284812.O14078Obg-like ATPase homolog; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP (By similarity).
mdb1 protein networkhttps://string-db.org/network/284812.O14079DNA damage response protein Mdb1; Involved in DNA damage response (DDR) mediated through its interaction with phosphorylated H2A proteins hta1 and hta2 which mark the discrete foci of DNA damage.
SPACUNK4.15 protein networkhttps://string-db.org/network/284812.O14080Uncharacterized protein UNK4,15.
tps3 protein networkhttps://string-db.org/network/284812.O14081Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 106 kDa subunit.
SPACUNK4.17 protein networkhttps://string-db.org/network/284812.O14082Uncharacterized protein UNK4.17.
imt1 protein networkhttps://string-db.org/network/284812.O14084Inositol phosphoceramide mannosyltransferase 1; With imt2 and imt3, is required for the synthesis of mannosyl phosphorylinositol ceramide (MIPC). Catalyzes the addition of mannosyl to phosphoryli [...]
sec67 protein networkhttps://string-db.org/network/284812.O14085Translocation protein sec72; Acts as non-essential component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) an [...]
rpa49 protein networkhttps://string-db.org/network/284812.O14086DNA-directed RNA polymerase I subunit rpa49; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
rim1 protein networkhttps://string-db.org/network/284812.O14087Single-stranded DNA-binding protein rim1, mitochondrial; This protein binds preferentially and cooperatively to ss- DNA. Involved in mitochondrial DNA replication (By similarity).
SPAC2F3.05c protein networkhttps://string-db.org/network/284812.O14088Uncharacterized oxidoreductase C2F3.05c.
kap104 protein networkhttps://string-db.org/network/284812.O14089Importin subunit beta-2; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for arginine/glycine-rich nuclear localization signals (rg-NLS) and PY-NLS in cargo [...]
sut1 protein networkhttps://string-db.org/network/284812.O14091General alpha-glucoside permease; Responsible for the transport of maltose and sucrose into the cell, with the concomitant uptake of protons (symport system). Belongs to the glycoside-pentoside-h [...]
hem1 protein networkhttps://string-db.org/network/284812.O140925-aminolevulinate synthase, mitochondrial; Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
vps54 protein networkhttps://string-db.org/network/284812.O14093Vacuolar protein sorting-associated protein 54; Involved in retrograde transport from early and late endosomes to late Golgi by linking the vesicle through the t-SNARE TGL1 to the Golgi, leading [...]
ppx1 protein networkhttps://string-db.org/network/284812.O14094Putative exopolyphosphatase; Degradation of inorganic polyphosphates.
plp1 protein networkhttps://string-db.org/network/284812.O14095Thioredoxin domain-containing protein plp1; Inhibits early G-protein signaling events following pheromone stimulation. May help create heterodimerizable beta-tubulin by facilitating the efficient [...]
qtr2 protein networkhttps://string-db.org/network/284812.O14096Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) [...]
saf2 protein networkhttps://string-db.org/network/284812.O14097WW domain-containing protein C2F3.14c.
lsk1 protein networkhttps://string-db.org/network/284812.O14098CTD kinase subunit alpha; Catalytic subunit of the CTDK-I complex, which hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit. Involved in [...]
SPAC2F3.16 protein networkhttps://string-db.org/network/284812.O14099Uncharacterized RING finger protein C2F3.16.
zds1 protein networkhttps://string-db.org/network/284812.O14100Protein zds1; Has a role in establishing cell polarity. Also required for maintenance of cell wall integrity, sexual differentiation, calcium tolerance and cell morphology. Involved in Ras-MAPK s [...]
sap49 protein networkhttps://string-db.org/network/284812.O14102Spliceosome-associated protein 49.
rot1 protein networkhttps://string-db.org/network/284812.O14103Protein rot1; Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wa [...]
lys12 protein networkhttps://string-db.org/network/284812.O14104Homoisocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
rpe1 protein networkhttps://string-db.org/network/284812.O14105Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
dni1 protein networkhttps://string-db.org/network/284812.O14107Cell fusion protein dni1; Cell membrane protein which plays a relevant role in coordinating membrane organization and cell wall remodeling during mating; Belongs to the SUR7 family.
eta2 protein networkhttps://string-db.org/network/284812.O14108DNA-binding protein eta2.
maf1 protein networkhttps://string-db.org/network/284812.O14109Repressor of RNA polymerase III transcription maf1; Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
gcv1 protein networkhttps://string-db.org/network/284812.O14110Probable aminomethyltransferase, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
psd3 protein networkhttps://string-db.org/network/284812.O14111Phosphatidylserine decarboxylase 3 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and [...]
rps1001 protein networkhttps://string-db.org/network/284812.O1411240S ribosomal protein S10-A.
sde2 protein networkhttps://string-db.org/network/284812.O14113Telomere maintenance protein SDE2; Plays a role in the regulation of telomeric and centromeric silencing. Contributes to the prevention of abnormal telomere elongation. Required for chromosome se [...]
abo1 protein networkhttps://string-db.org/network/284812.O14114Uncharacterized AAA domain-containing protein C31G5.19.
ptl2 protein networkhttps://string-db.org/network/284812.O14115Patatin-like phospholipase domain-containing protein SPAC1786.01c; Probable lipid hydrolase; Belongs to the PLPL family.
msn5 protein networkhttps://string-db.org/network/284812.O14116Uncharacterized protein C328.01c.
efm3 protein networkhttps://string-db.org/network/284812.O14118Protein-lysine N-methyltransferase efm3; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 2. Belongs to the class I-like SAM-binding methylt [...]
sei1 protein networkhttps://string-db.org/network/284812.O14119Seipin homolog; Involved in lipid metabolism and lipid droplet (LD) morphology, number, and size. Facilitates initiation of LD formation, and ensures that vectorial budding of LDs from the ER is [...]
mvp1 protein networkhttps://string-db.org/network/284812.O14120Sorting nexin mvp1; Required for vacuolar protein sorting.
nde1 protein networkhttps://string-db.org/network/284812.O14121Probable NADH-ubiquinone oxidoreductase C3A11.07, mitochondrial; Catalyzes the oxidation of NADH.
cul4 protein networkhttps://string-db.org/network/284812.O14122Cullin-4; Required, indirectly, for activation of ribonucleotide reductase through the degradation of the protein spd1, thereby supplying deoxyribonucleotides for DNA replication and repair. Also [...]
dpe1 protein networkhttps://string-db.org/network/284812.O14124Uncharacterized dipeptidase C3A11.10c.
SPAC3A11.11c protein networkhttps://string-db.org/network/284812.O14125Uncharacterized oxidoreductase C3A11.11c.
rpt5 protein networkhttps://string-db.org/network/284812.O1412626S proteasome regulatory subunit 6A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and subs [...]
sac12 protein networkhttps://string-db.org/network/284812.O14127Uncharacterized protein C3C7.01c; To yeast RSD1 and S.pombe SpBC19F5.03.
pil2 protein networkhttps://string-db.org/network/284812.O14128Probable sphingolipid long chain base-responsive protein pil2; Negative regulator of cell wall integrity (CWI) in unstressed cells, probably by inhibiting protein kinase ksg1/ppk21 activity and r [...]
rad55 protein networkhttps://string-db.org/network/284812.O14129DNA repair protein rhp55; Required for radiation resistance and meiotic viability and acts in recombination and recombinational DNA repair pathways.
SPAC3C7.04 protein networkhttps://string-db.org/network/284812.O14130Uncharacterized transcriptional regulatory protein C3C7.04.
mug191 protein networkhttps://string-db.org/network/284812.O14131Meiotically up-regulated gene 191 protein; Has a role in meiosis.
pit1 protein networkhttps://string-db.org/network/284812.O14132Sporulation protein kinase pit1; Protein kinase which is essential for spore formation.
ate1 protein networkhttps://string-db.org/network/284812.O14133Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradatio [...]
elf1 protein networkhttps://string-db.org/network/284812.O14134mRNA export factor elf1; Has a direct role in the mRNA export process. Appears to act within the rae1 mediated mRNA export pathway. Belongs to the ABC transporter superfamily. ABCF family. EF3 su [...]
set8 protein networkhttps://string-db.org/network/284812.O14135SET domain-containing protein 8.
pex13 protein networkhttps://string-db.org/network/284812.O14136Peroxisomal membrane protein pex13; Component of the peroxisomal translocation machinery with pex14 and pex17; Belongs to the peroxin-13 family.
SPAC3C7.13c protein networkhttps://string-db.org/network/284812.O14137Probable glucose-6-phosphate 1-dehydrogenase C7.13c; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates [...]
SPAC25A8.03c protein networkhttps://string-db.org/network/284812.O14138Protein arginine methyltransferase NDUFAF7 homolog, mitochondrial; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (comple [...]
hrp3 protein networkhttps://string-db.org/network/284812.O14139Chromodomain helicase hrp3; Involved in heterochromatin silencing. Required for transcriptional repression at the silence loci of mat3, where it has a direct role as a chromatin remodeling factor [...]
rpn15 protein networkhttps://string-db.org/network/284812.O1414026S proteasome complex subunit rpn15; Versatile protein that might stabilize multiple protein complexes involved in diverse pathways. Subunit of the 26S proteasome which plays a role in ubiquitin [...]
SPAC3G6.03c protein networkhttps://string-db.org/network/284812.O14141dTTP/UTP pyrophosphatase; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleo [...]
SPAC3G6.05 protein networkhttps://string-db.org/network/284812.O14142Protein sym1.
SPAC3G6.07 protein networkhttps://string-db.org/network/284812.O14143Uncharacterized protein C3G6.07.
erv1 protein networkhttps://string-db.org/network/284812.O14144Mitochondrial FAD-linked sulfhydryl oxidase erv1; FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation. Required for the import and folding of small cysteine- containing prote [...]
tps2 protein networkhttps://string-db.org/network/284812.O14145Trehalose-phosphatase; Phosphatase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6- phosphate and UDP-glucose in a two step process; [...]
vps51 protein networkhttps://string-db.org/network/284812.O14146Vacuolar protein sorting-associated protein 51; Involved in retrograde transport from early and late endosomes to late Golgi, leading to the membrane fusion between late Golgi and endosomal vesic [...]
chl1 protein networkhttps://string-db.org/network/284812.O14147ATP-dependent DNA helicase chl1; ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topo [...]
ino80 protein networkhttps://string-db.org/network/284812.O14148Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
mde5 protein networkhttps://string-db.org/network/284812.O14154Alpha-amylase mde5.
SPAC4A8.02c protein networkhttps://string-db.org/network/284812.O14155UPF0047 protein C4A8.02c; Belongs to the UPF0047 family.
ptc4 protein networkhttps://string-db.org/network/284812.O14156Protein phosphatase 2C homolog 4; Has a role in the regulation of vacuole fusion.
myp2 protein networkhttps://string-db.org/network/284812.O14157Myosin type-2 heavy chain 2; Stabilizes the F-actin cables forming the F-actin ring that surrounds the nucleus during interphase. May work in conjunction with myo2; Belongs to the TRAFAC class my [...]
SPAC4A8.06c protein networkhttps://string-db.org/network/284812.O14158AB hydrolase superfamily protein C4A8.06c.
lcb4 protein networkhttps://string-db.org/network/284812.O14159Sphingoid long chain base kinase 4; Catalyzes the phosphorylation of the sphingoid long chain bases dihydrosphingosine (DHS) and phytosphingosine (PHS) to form dihydrosphingosine 1-phosphate (DHS [...]
vrs2 protein networkhttps://string-db.org/network/284812.O14160Valine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
cwf21 protein networkhttps://string-db.org/network/284812.O14161Pre-mRNA-splicing factor cwf21; Involved in pre-mRNA splicing. May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome. May do so by stabilizin [...]
rog1 protein networkhttps://string-db.org/network/284812.O14162Putative lipase C4A8.10; Belongs to the putative lipase ROG1 family.
tif303 protein networkhttps://string-db.org/network/284812.O14164Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoi [...]
pud1 protein networkhttps://string-db.org/network/284812.O14165Uncharacterized protein C4C5.01; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
pgc1 protein networkhttps://string-db.org/network/284812.O14169Phosphatidylglycerol phospholipase C; Phosphatidylglycerol phospholipase required for the removal of excess phosphatidylglycerol (PG) via a phospholipase C-type degradation mechanism; Belongs to [...]
pop2 protein networkhttps://string-db.org/network/284812.O14170WD repeat-containing protein pop2; Involved in maintenance of ploidy through proteasome dependent degradation of CDK inhibitor rum1 and S-phase initiator cdc18. Functions as a recognition factor [...]
rer2 protein networkhttps://string-db.org/network/284812.O14171Dehydrodolichyl diphosphate synthase complex subunit SPAC4D7.04c; With nus1, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Do [...]
met8 protein networkhttps://string-db.org/network/284812.O14172Siroheme biosynthesis protein met8; Catalyzes the conversion of precorrin-2 into siroheme. This reaction consist of the NAD-dependent oxidation of precorrin-2 into sirohydrochlorin and its subseq [...]
csi2 protein networkhttps://string-db.org/network/284812.O14173Uncharacterized protein C4D7.07c.
spt20 protein networkhttps://string-db.org/network/284812.O14174SAGA complex subunit spt20; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcri [...]
dsc4 protein networkhttps://string-db.org/network/284812.O14175DSC E3 ubiquitin ligase complex subunit 4; Component of the DSC E3 ubiquitin ligase complex which is required for the sre1 transcriptional activator proteolytic cleavage to release the soluble tr [...]
usp104 protein networkhttps://string-db.org/network/284812.O14176Pre-mRNA-processing protein prp40; Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U1 (By similarity).
did4 protein networkhttps://string-db.org/network/284812.O14177ESCRT-III complex subunit did4; Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). Ac [...]
mrpl40 protein networkhttps://string-db.org/network/284812.O1417854S ribosomal protein L40, mitochondrial; Involved in mitochondrial genome encoded proteins translation.
sdo1 protein networkhttps://string-db.org/network/284812.O14179Ribosome maturation protein sdo1; Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with the EF-2-like GTPase ria1, may trigger the GTP-d [...]
SPAC4F8.04 protein networkhttps://string-db.org/network/284812.O14180Brix domain-containing protein C4F8.04.
mrpl28 protein networkhttps://string-db.org/network/284812.O1418154S ribosomal protein L28, mitochondrial; Involved in mitochondrial genome encoded proteins translation.
mrps12 protein networkhttps://string-db.org/network/284812.O14182Probable 37S ribosomal protein S12, mitochondrial.
stg1 protein networkhttps://string-db.org/network/284812.O14185Transgelin; Has actin-binding and actin-bundling activity and is a component of the actin patch. Stabilizes actin filaments against disassembly. Cross-links F-actin and is required for the format [...]
sea2 protein networkhttps://string-db.org/network/284812.O14186Uncharacterized WD repeat-containing protein C4F8.11.
spp42 protein networkhttps://string-db.org/network/284812.O14187Pre-mRNA-splicing factor spp42; Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures [...]
rng2 protein networkhttps://string-db.org/network/284812.O14188Ras GTPase-activating-like protein rng2; Required for cytokinesis. Component of the contractile F- actin ring; required for its construction following assembly of F-actin at the division site.
SPAC10F6.17c protein networkhttps://string-db.org/network/284812.O14189Protein phosphatase 2C homolog C10F6.17c; Involved in regulation of pyruvate dehydrogenase activity.
alg13 protein networkhttps://string-db.org/network/284812.O14190UDP-N-acetylglucosamine transferase subunit alg13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway (By similarity). Belongs to th [...]
SPAC56E4.03 protein networkhttps://string-db.org/network/284812.O14192Aromatic amino acid aminotransferase C56E4.03; Has aromatic amino acid transaminase activity. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
snd2 protein networkhttps://string-db.org/network/284812.O14193SRP-independent targeting protein 2 homolog; May function in a SRP (signal recognition particle) and GET (guided entry of tail-anchored proteins) independent pathway for targeting a broad range o [...]
ggt2 protein networkhttps://string-db.org/network/284812.O14194Glutathione hydrolase 2 heavy chain; Catalyzes the transfer of the gamma-glutamyl moiety of glutathione (GSH) and other gamma-glutamyl compounds to amino acids and peptides. Major GSH-degrading e [...]
mug165 protein networkhttps://string-db.org/network/284812.O14196Meiotically up-regulated gene 165 protein; Has a role in meiosis.
SPAC5D6.04 protein networkhttps://string-db.org/network/284812.O14197Uncharacterized transporter C5D6.04.
med18 protein networkhttps://string-db.org/network/284812.O14198Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
alg14 protein networkhttps://string-db.org/network/284812.O14199UDP-N-acetylglucosamine transferase subunit alg14; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit [...]
pxa1 protein networkhttps://string-db.org/network/284812.O14200PXA domain protein 1; Required for required for normal vacuolar morphology and for vacuolar protein transport. Also required for endosome-to-Golgi protein transport.
mug86 protein networkhttps://string-db.org/network/284812.O14201Meiotically up-regulated gene 86 protein; Has a role in meiosis; Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
mtf2 protein networkhttps://string-db.org/network/284812.O14204Uncharacterized protein C5D6.12.
gpp74 protein networkhttps://string-db.org/network/284812.O14205Vacuolar protein sorting-associated protein 74; Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required f [...]
SPAC1B9.03c protein networkhttps://string-db.org/network/284812.O14206Brix domain-containing protein C1B9.03c.
mus7 protein networkhttps://string-db.org/network/284812.O14207Protein mms22; Involved in protection against replication-dependent DNA damage. May act by restoring active replication forks, repairing unusual DNA structures, and/or preventing aberrant DNA rea [...]
bit2 protein networkhttps://string-db.org/network/284812.O14208Uncharacterized protein C6B12.03c.
SPAC6B12.04c protein networkhttps://string-db.org/network/284812.O14209Uncharacterized aminotransferase C6B12.04c; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
ies2 protein networkhttps://string-db.org/network/284812.O14210INO80 complex subunit 2; Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
rrg9 protein networkhttps://string-db.org/network/284812.O14211Required for respiratory growth protein 9, mitochondrial; Required for respiratory activity and maintenance and expression of the mitochondrial genome; Belongs to the RRG9 family.
pqr1 protein networkhttps://string-db.org/network/284812.O14212Uncharacterized RING finger protein C6B12.07c.
epr1 protein networkhttps://string-db.org/network/284812.O14213Meiotically up-regulated gene 185 protein; Has a role in meiosis.
trm10 protein networkhttps://string-db.org/network/284812.O14214tRNA (guanine(9)-N1)-methyltransferase; S-adenosyl-L-methionine-dependent guanine N(1)- methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tR [...]
spp1 protein networkhttps://string-db.org/network/284812.O14215DNA primase small subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type pri [...]
drc1 protein networkhttps://string-db.org/network/284812.O14216DNA replication regulator sld2; Has a role in the initiation of DNA replication. Required at S-phase checkpoint; Belongs to the SLD2 family.
tom70 protein networkhttps://string-db.org/network/284812.O14217Probable mitochondrial import receptor subunit tom70; Receptor that accelerates the import of all mitochondrial precursor proteins.
SPAC6B12.13 protein networkhttps://string-db.org/network/284812.O14218Type 1 phosphatases regulator ypi1; Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control; Belongs to the YPI1 family.
meu26 protein networkhttps://string-db.org/network/284812.O14220Meiotic expression up-regulated protein 26.
fsv1 protein networkhttps://string-db.org/network/284812.O14222Syntaxin-like protein fsv1; Involved in vesicle-mediated protein transport between the Golgi and the vacuole.
tvp15 protein networkhttps://string-db.org/network/284812.O14223Golgi apparatus membrane protein tvp15; Golgi membrane protein involved in vesicular trafficking. Belongs to the TVP15 family.
rdi1 protein networkhttps://string-db.org/network/284812.O14224Rho GDP-dissociation inhibitor; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
tom20 protein networkhttps://string-db.org/network/284812.O14225Mitochondrial import receptor subunit tom20; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. To [...]
exo84 protein networkhttps://string-db.org/network/284812.O14226Exocyst complex component exo84; Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Plays a role in both the assembly of [...]
rdp1 protein networkhttps://string-db.org/network/284812.O14227RNA-dependent RNA polymerase 1; Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation, accurate chromosome segregation, centromere cohesion and telome [...]
ade3 protein networkhttps://string-db.org/network/284812.O14228Probable phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglyci [...]
sfc1 protein networkhttps://string-db.org/network/284812.O14229Transcription factor tau subunit sfc1; TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the i [...]
fps1 protein networkhttps://string-db.org/network/284812.O14230Farnesyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geran [...]
mtr4 protein networkhttps://string-db.org/network/284812.O14232ATP-dependent RNA helicase mtr4; Component of the TRAMP complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism limiting inappropri [...]
rna14 protein networkhttps://string-db.org/network/284812.O14233mRNA 3'-end-processing protein rna14; Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end forma [...]
cch1 protein networkhttps://string-db.org/network/284812.O14234Calcium-channel protein cch1; Voltage-gated, high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones. Function [...]
pof5 protein networkhttps://string-db.org/network/284812.O14235Protein pof5.
nog2 protein networkhttps://string-db.org/network/284812.O14236Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/ [...]
ost2 protein networkhttps://string-db.org/network/284812.O14238Probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glyc [...]
rax2 protein networkhttps://string-db.org/network/284812.O14239Polarized growth protein rax2; Controls cell polarity, through the G1 phase of mitosis, via regulation of for3 localization. Required for actin cable formation where it directs the spatial distri [...]
eaf6 protein networkhttps://string-db.org/network/284812.O14240Chromatin modification-related protein eaf6; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation o [...]
arc2 protein networkhttps://string-db.org/network/284812.O14241Actin-related protein 2/3 complex subunit 2; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nuc [...]
SPAC6F6.11c protein networkhttps://string-db.org/network/284812.O14242Putative pyridoxal kinase C6F6.11c; Required for synthesis of pyridoxal-5-phosphate from vitamin B6; Belongs to the pyridoxine kinase family.
atg24 protein networkhttps://string-db.org/network/284812.O14243Sorting nexin-4; Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells. Involved in retrieval of late-Golgi SNAREs from post-Golgi endoso [...]
SPAC6F6.13c protein networkhttps://string-db.org/network/284812.O14244Uncharacterized membrane protein C6F6.13c.
tpz1 protein networkhttps://string-db.org/network/284812.O14246Protection of telomeres protein tpz1; Telomeric DNA-binding protein that is required to protect the 3'-end telomeric overhang and involved in telomere length regulation. recruits poz1 and ccq1 to [...]
tea3 protein networkhttps://string-db.org/network/284812.O14248Tip elongation aberrant protein 3; Acts as a cell end marker required for efficient new end take-off (NETO), whereby growth is activated at the cell end to generate bipolarity in extending cells. [...]
cld1 protein networkhttps://string-db.org/network/284812.O14249Probable cardiolipin-specific deacylase, mitochondrial; Mitochondrial cardiolipin-specific phospholipase which deacylates de novo synthesized cardiolipin. Part of the remodeling process of cardio [...]
pre5 protein networkhttps://string-db.org/network/284812.O14250Probable proteasome subunit alpha type-6; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent [...]
trs120 protein networkhttps://string-db.org/network/284812.O14251Transport protein particle subunit trs120; Component of the TRAPP II complex. TRAPP II seems to play a role in intra-Golgi transport (By similarity).
tda3 protein networkhttps://string-db.org/network/284812.O14252Putative oxidoreductase C6G10.06; Putative oxidoreductase that negatively regulates the retrieval of cargo from late endosomes to the Golgi.
cbc1 protein networkhttps://string-db.org/network/284812.O14253Nuclear cap-binding protein subunit 1; Component of the CBC complex, which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in maturation, export and degradation of nuclear mR [...]
idp1 protein networkhttps://string-db.org/network/284812.O14254Probable isocitrate dehydrogenase [NADP], mitochondrial.
gls1 protein networkhttps://string-db.org/network/284812.O14255Probable mannosyl-oligosaccharide glucosidase; Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor highly specifically.
SPAC6G10.10c protein networkhttps://string-db.org/network/284812.O14256Uncharacterized protein C6G10.10c.
ace2 protein networkhttps://string-db.org/network/284812.O14258Metallothionein expression activator; Regulates the transcription of genes required for cell separation.
sfp47 protein networkhttps://string-db.org/network/284812.O14259Ubp4-interactor sfp47; Required for the regulation of activity and recruitment of ubp4 to endosomes.
ahk1 protein networkhttps://string-db.org/network/284812.O14260UPF0592 membrane protein C7D4.03c.
atg11 protein networkhttps://string-db.org/network/284812.O14261Taz1-interacting factor 1; Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) [...]
SPAC7D4.05 protein networkhttps://string-db.org/network/284812.O14262Putative uncharacterized hydrolase C7D4.05.
SPAC7D4.08 protein networkhttps://string-db.org/network/284812.O14263Uncharacterized protein C7D4.08.
dfg10 protein networkhttps://string-db.org/network/284812.O14264Uncharacterized protein C7D4.09c.
vma13 protein networkhttps://string-db.org/network/284812.O14265V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATP [...]
sec39 protein networkhttps://string-db.org/network/284812.O14266Protein transport protein sec39; Required for protein transport between the Golgi and the endoplasmic reticulum. May contribute to tethering of coatomer-coated retrograde transport vesicles to th [...]
iss10 protein networkhttps://string-db.org/network/284812.O14269Uncharacterized protein C7D4.14c.
fhl1 protein networkhttps://string-db.org/network/284812.O14270Fork head transcription factor 1; Acts as a transcriptional activator with a role in the regulation of mitosis. Required for the correct timing, positioning and contraction of the division septum [...]
SPAC8C9.04 protein networkhttps://string-db.org/network/284812.O14273Meiotically up-regulated protein C8C9.04; Has a role in meiosis and sporulation.
dtd1 protein networkhttps://string-db.org/network/284812.O14274D-aminoacyl-tRNA deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischargin [...]
ppr4 protein networkhttps://string-db.org/network/284812.O14275Pentatricopeptide repeat-containing protein 4, mitochondrial; Mitochondrial RNA-binding protein that specifically activates the translation of the cox1 mRNA.
fyv7 protein networkhttps://string-db.org/network/284812.O14276rRNA-processing protein fyv7; Involved in the processing of the 20S pre-rRNA. Belongs to the FYV7 family.
rps5 protein networkhttps://string-db.org/network/284812.O1427740S ribosomal protein S5-A.
rrp14 protein networkhttps://string-db.org/network/284812.O14279Ribosomal RNA-processing protein 14-N; Involved in ribosome biogenesis and cell polarity. Required for the synthesis of both 40S and 60S ribosomal subunits and may also play some direct role in c [...]
fra2 protein networkhttps://string-db.org/network/284812.O14280Uncharacterized bolA-like protein C8C9.11; Belongs to the BolA/IbaG family.
mrs3 protein networkhttps://string-db.org/network/284812.O14281Uncharacterized mitochondrial carrier C8C9.12c.
prr1 protein networkhttps://string-db.org/network/284812.O14283Transcription factor prr1; Involved in oxidative stress. Transcription factor that acts upon trr1 and ctt1; In the N-terminal section; belongs to the HSF family.
oxr1 protein networkhttps://string-db.org/network/284812.O14284Oxidation resistance protein 1; May be involved in protection from oxidative damage (By similarity). Has a role in meiosis; Belongs to the OXR1 family.
spc34 protein networkhttps://string-db.org/network/284812.O14285DASH complex subunit spc34; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates [...]
atm1 protein networkhttps://string-db.org/network/284812.O14286Iron-sulfur clusters transporter atm1, mitochondrial; Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster pr [...]
leu2 protein networkhttps://string-db.org/network/284812.O142893-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate; Belongs to the aconitase/IPM isomerase family [...]
SPAC9E9.04 protein networkhttps://string-db.org/network/284812.O14290Uncharacterized protein C9E9.04.
atd1 protein networkhttps://string-db.org/network/284812.O14293Putative aldehyde dehydrogenase-like protein C9E9.09c; Belongs to the aldehyde dehydrogenase family.
plr1 protein networkhttps://string-db.org/network/284812.O14295Pyridoxal reductase; Catalyzes the reduction of pyridoxal (PL) with NADPH and oxidation of pyridoxine (PN) with NADP(+).
vps24 protein networkhttps://string-db.org/network/284812.O14296Vacuolar protein sorting-associated protein 24; Class E VPS protein implicated in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal [...]
SPAC9E9.15 protein networkhttps://string-db.org/network/284812.O14297Uncharacterized protein C9E9.15.
wis4 protein networkhttps://string-db.org/network/284812.O14299MAP kinase kinase kinase wis4; Involved in a signal transduction pathway that is activated in under conditions of heat shock, oxidative stress or limited nutrition. Unlike win1, it is not activat [...]
oxa101 protein networkhttps://string-db.org/network/284812.O14300Mitochondrial inner membrane protein oxa1-1; Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome [...]
aip1 protein networkhttps://string-db.org/network/284812.O14301Uncharacterized WD repeat-containing protein C9G1.05; Belongs to the WD repeat AIP1 family.
cyk3 protein networkhttps://string-db.org/network/284812.O14302Cytokinesis protein 3; Involved in cytokinesis; Belongs to the CYK3 family.
SPAC9G1.07 protein networkhttps://string-db.org/network/284812.O14303Uncharacterized protein C9G1.07.
SPAC9G1.08c protein networkhttps://string-db.org/network/284812.O14304Uncharacterized hydrolase C9G1.08c; Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
sid1 protein networkhttps://string-db.org/network/284812.O14305Serine/threonine-protein kinase sid1; Has a role in the septation initiation network (SIN) required for cytokinesis.
inp53 protein networkhttps://string-db.org/network/284812.O14306Probable inositol polyphosphate 5-phosphatase C9G1.10c.
cpd1 protein networkhttps://string-db.org/network/284812.O14307tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit trm61; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 [...]
swc4 protein networkhttps://string-db.org/network/284812.O14308SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by [...]
npp106 protein networkhttps://string-db.org/network/284812.O14310Nucleoporin npp106; Has a role in promoting mRNA export from the nucleus.
spt3 protein networkhttps://string-db.org/network/284812.O14311SAGA complex subunit spt3; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. SAGA is involved in RNA polymerase II-dependent transcriptional regulatio [...]
pmp20 protein networkhttps://string-db.org/network/284812.O14313Peroxisomal membrane associated protein 20; May act as a chaperone rather than a peroxidase. Has no thioredoxin-dependent peroxidase activity. Shows weak chaperone activity; Belongs to the peroxi [...]
rpp203 protein networkhttps://string-db.org/network/284812.O1431760S acidic ribosomal protein P2-C; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family.
php4 protein networkhttps://string-db.org/network/284812.O14318CCAAT-binding factor complex subunit php4; Component of the transcription regulatory CCAAT-binding complex. Required for the reprogramming of the cell for iron use. Downregulates pcl1, sdh4, and [...]
SPBC16E9.02c protein networkhttps://string-db.org/network/284812.O14319CUE domain-containing protein 5.
coa1 protein networkhttps://string-db.org/network/284812.O14320Cytochrome c oxidase assembly factor 1; Required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane. Involved in a step coupling MSS51- dependent cotranslational i [...]
erg6 protein networkhttps://string-db.org/network/284812.O14321Sterol 24-C-methyltransferase erg6; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of lanosterol to form eburicol (Probable). Involved in the biosynthesis or ergosterol whic [...]
mug100 protein networkhttps://string-db.org/network/284812.O14322Meiotically up-regulated gene 100 protein, mitochondrial; Has a role in meiosis.
mcp4 protein networkhttps://string-db.org/network/284812.O14323Meiotic coiled-coil protein 4; Has a role in meiosis.
erp5 protein networkhttps://string-db.org/network/284812.O14324Uncharacterized membrane protein C16E9.09c.
rix7 protein networkhttps://string-db.org/network/284812.O14325Uncharacterized AAA domain-containing protein C16E9.10c.
pub3 protein networkhttps://string-db.org/network/284812.O14326E3 ubiquitin-protein ligase pub3; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin [...]
pab2 protein networkhttps://string-db.org/network/284812.O14327Polyadenylate-binding protein 2.
ksp1 protein networkhttps://string-db.org/network/284812.O14328Serine/threonine-protein kinase ksp1.
zrg17 protein networkhttps://string-db.org/network/284812.O14329Probable zinc transporter zrg17; Probable transporter involved in the regulation of zinc homeostasis; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfa [...]
SPBC16E9.15 protein networkhttps://string-db.org/network/284812.O14330Uncharacterized protein C16E9.15; Belongs to the HSBP1 family.
rem1 protein networkhttps://string-db.org/network/284812.O14332Meiosis-specific cyclin rem1; Required for pre-meiotic DNA synthesis and S phase progression. Regulates levels of meiotic intragenic recombination.
psd1 protein networkhttps://string-db.org/network/284812.O14333Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid me [...]
pfd1 protein networkhttps://string-db.org/network/284812.O14334Probable prefoldin subunit 1; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in [...]
scr1 protein networkhttps://string-db.org/network/284812.O14335DNA-binding protein scr1; Involved in carbon catabolite repression. Represses the transcription of various genes including the inv1 gene. Belongs to the creA/MIG C2H2-type zinc-finger protein fam [...]
clg1 protein networkhttps://string-db.org/network/284812.O14336Meiotically up-regulated gene 80 protein; Has a role in meiosis.
mrpl7 protein networkhttps://string-db.org/network/284812.O14337Probable 54S ribosomal protein L7, mitochondrial.
ebs1 protein networkhttps://string-db.org/network/284812.O14338Uncharacterized serine-rich protein C2F12.03c.
rpl1701 protein networkhttps://string-db.org/network/284812.O1433960S ribosomal protein L17-A.
osh2 protein networkhttps://string-db.org/network/284812.O14340Oxysterol-binding protein homolog C2F12.05c.
mrpl35 protein networkhttps://string-db.org/network/284812.O1434154S ribosomal protein L35, mitochondrial; Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily.
cay1 protein networkhttps://string-db.org/network/284812.O14342Uncharacterized protein C2F12.12c.
klp5 protein networkhttps://string-db.org/network/284812.O14343Kinesin-like protein 5; Has a role in establishing metaphase during mitosis. Required for chromosome segregation where it generates tension during kinetochore capturing; Belongs to the TRAFAC cla [...]
gua1 protein networkhttps://string-db.org/network/284812.O14344Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesi [...]
pfa3 protein networkhttps://string-db.org/network/284812.O14345Palmitoyltransferase pfa3; Palmitoyltransferase specific for VAC8. Palmitoylates VAC8 at one or more of its N-terminal cysteine residues, which is required for its proper membrane localization (B [...]
phs1 protein networkhttps://string-db.org/network/284812.O14346Probable very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic p [...]
ncb2 protein networkhttps://string-db.org/network/284812.O14348Negative cofactor 2 complex subunit beta.
isn1 protein networkhttps://string-db.org/network/284812.O14349IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family.
swi3 protein networkhttps://string-db.org/network/284812.O14350Swi1-interacting protein swi3; Forms a fork protection complex (FPC) with swi1. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. It is required for progra [...]
SPBC30D10.05c protein networkhttps://string-db.org/network/284812.O14351Uncharacterized oxidoreductase C30D10.05c; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
lsm4 protein networkhttps://string-db.org/network/284812.O14352Probable U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
bpl1 protein networkhttps://string-db.org/network/284812.O14353Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase; Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl-CoA- carboxy [...]
mgm101 protein networkhttps://string-db.org/network/284812.O14354Mitochondrial genome maintenance protein mgm101; Performs an essential function in the repair of oxidatively damaged mtDNA that is required for the maintenance of the mitochondrial genome. Binds [...]
SPBC30D10.09c protein networkhttps://string-db.org/network/284812.O14355Uncharacterized membrane protein C30D10.09c.
tor1 protein networkhttps://string-db.org/network/284812.O14356Serine/threonine-protein kinase tor1; Phosphatidylinositol 3-kinase homolog, component of TORC2, which regulates multiple cellular processes to control cell growth in response to environmental si [...]
gpi1 protein networkhttps://string-db.org/network/284812.O14357N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein gpi1; Necessary for the synthesis of N-acetylglucosaminyl- phosphatidylinositol, the very early intermediate in GPI-anchor biosynthe [...]
rsm27 protein networkhttps://string-db.org/network/284812.O1435837S ribosomal protein S27, mitochondrial; Involved in mitochondrial genome encoded proteins translation.
SPBC30D10.14 protein networkhttps://string-db.org/network/284812.O14359Uncharacterized AIM2 family protein C30D10.14.
naf1 protein networkhttps://string-db.org/network/284812.O14360H/ACA ribonucleoprotein complex non-core subunit NAF1; RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs c [...]
pha2 protein networkhttps://string-db.org/network/284812.O14361Putative prephenate dehydratase; Putative prephenate dehydratase required for the syntheis of L-phenylalanine; Belongs to the PHA2 family.
smi1 protein networkhttps://string-db.org/network/284812.O14362Cell wall biosynthesis/cell cycle regulator smi1; Protein involved in the regulation of cell wall assembly and 1,3-beta-glucan synthesis, possibly through the transcriptional regulation of cell w [...]
rpl102 protein networkhttps://string-db.org/network/284812.O1436360S ribosomal protein L1-A.
rbd1 protein networkhttps://string-db.org/network/284812.O14364Uncharacterized protein C13E7.11.
gti1 protein networkhttps://string-db.org/network/284812.O14367Gluconate transport inducer 1; Promotes the onset of gluconate uptake upon glucose starvation.
hsp16 protein networkhttps://string-db.org/network/284812.O14368Heat shock protein 16; Belongs to the small heat shock protein (HSP20) family.
sce3 protein networkhttps://string-db.org/network/284812.O14369Probable RNA-binding protein sce3.
eca39 protein networkhttps://string-db.org/network/284812.O14370Branched-chain-amino-acid aminotransferase, mitochondrial; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine; Belongs to t [...]
rpl2701 protein networkhttps://string-db.org/network/284812.O1438860S ribosomal protein L27-A.
ned8 protein networkhttps://string-db.org/network/284812.O14399Ubiquitin-like protein 1; Belongs to the ubiquitin family.
gut2 protein networkhttps://string-db.org/network/284812.O14400Glycerol-3-phosphate dehydrogenase, mitochondrial; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
mad2 protein networkhttps://string-db.org/network/284812.O14417Mitotic spindle checkpoint component mad2; Feedback control that prevents cells with incompletely assembled spindles from leaving mitosis. It interacts with the anaphase promoting complex/cycloso [...]
cbh1 protein networkhttps://string-db.org/network/284812.O14423CENP-B homolog protein 1; Binds to centromeric K-type repeat DNA and ARS3002 DNA. The CBH-binding consensus sequence is Py-Pu-A-T-A-T-Py-Pu-T-A.
fet5 protein networkhttps://string-db.org/network/284812.O14443GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.
pfd6 protein networkhttps://string-db.org/network/284812.O14450Probable prefoldin subunit 6; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in [...]
rpb7 protein networkhttps://string-db.org/network/284812.O14459DNA-directed RNA polymerase II subunit rpb7; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
eft201 protein networkhttps://string-db.org/network/284812.O14460Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
trx1 protein networkhttps://string-db.org/network/284812.O14463Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
dpm1 protein networkhttps://string-db.org/network/284812.O14466Dolichol-phosphate mannosyltransferase; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading [...]
ssr2 protein networkhttps://string-db.org/network/284812.O14470SWI/SNF and RSC complexes subunit ssr2; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particula [...]
ape4 protein networkhttps://string-db.org/network/284812.O36014Aspartyl aminopeptidase 1; Aspartyl aminopeptidase that is able to remove aspartyl residue at N-terminus of angiotensin I. Acts also as a chaperone and efficiently suppressed the thermal aggregat [...]
trm7 protein networkhttps://string-db.org/network/284812.O36015Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
ypa1 protein networkhttps://string-db.org/network/284812.O36016Serine/threonine-protein phosphatase 2A activator 1; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as [...]
lip2 protein networkhttps://string-db.org/network/284812.O36017Probable octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP ca [...]
bud22 protein networkhttps://string-db.org/network/284812.O36018Protein bud22.
atg13 protein networkhttps://string-db.org/network/284812.O36019Autophagy protein 13; Activates the atg1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Also involved in cytoplasm to vacuole transport (Cvt) an [...]
mug126 protein networkhttps://string-db.org/network/284812.O36020Meiotically up-regulated gene 126 protein; Has a role in meiosis.
noc1 protein networkhttps://string-db.org/network/284812.O36021Uncharacterized protein C4F10.09c; Belongs to the CBF/MAK21 family.
mnn9 protein networkhttps://string-db.org/network/284812.O36022Mannan polymerase complex subunit mnn9; Required for the addition of the long alpha 1,6-mannose backbone of N-linked glycans on cell wall and periplasmic proteins.
spn1 protein networkhttps://string-db.org/network/284812.O36023Septin homolog spn1; Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells.
fta1 protein networkhttps://string-db.org/network/284812.O36024Inner kinetochore subunit fta1; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segre [...]
mpd2 protein networkhttps://string-db.org/network/284812.O36025GYF domain-containing protein mpd2; Has a role in mRNA export from the nucleus. Belongs to the SMY2/mpd2 family.
wsp1 protein networkhttps://string-db.org/network/284812.O36027Wiskott-Aldrich syndrome protein homolog 1; Has a role in regulating actin assembly, so regulating polarized growth.
SPAC4F10.16c protein networkhttps://string-db.org/network/284812.O36028Putative phospholipid-transporting ATPase C4F10.16c; Catalyzes the hydrolysis of ATP coupled with the transport of phospholipids.
nup37 protein networkhttps://string-db.org/network/284812.O36030Uncharacterized WD repeat-containing protein C4F10.18.
hit1 protein networkhttps://string-db.org/network/284812.O36031Uncharacterized zinc-finger protein C4F10.19c.
grx1 protein networkhttps://string-db.org/network/284812.O36032Glutaredoxin-1; The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also [...]
SPAC19B12.01 protein networkhttps://string-db.org/network/284812.O36033TPR repeat-containing protein C19B12.01.
dmc1 protein networkhttps://string-db.org/network/284812.O42634Meiotic recombination protein dmc1; Required for meiotic recombination and cell cycle progression. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependen [...]
prp22 protein networkhttps://string-db.org/network/284812.O42643Pre-mRNA-splicing factor ATP-dependent RNA helicase prp22; Acts late in the splicing of pre-mRNA. Required for the splicing of introns with a branch nucleotide to 3'-splice site distance greater [...]
cts1 protein networkhttps://string-db.org/network/284812.O42644CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
ats1 protein networkhttps://string-db.org/network/284812.O42645RCC1 repeat-containing protein C10F6.04.
ubc6 protein networkhttps://string-db.org/network/284812.O42646Ubiquitin-conjugating enzyme E2 6; Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in degradation of misfolded or regulated proteins localized in the endoplasmic retic [...]
nht1 protein networkhttps://string-db.org/network/284812.O42648HMG box-containing protein C10F6.08c.
psm3 protein networkhttps://string-db.org/network/284812.O42649Structural maintenance of chromosomes protein 3; Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the [...]
rio1 protein networkhttps://string-db.org/network/284812.O42650Serine/threonine-protein kinase rio1; Required for the final endonucleolytic cleavage at site D converting 20S pre-rRNA into the mature 18S rRNA. Required for the final steps of cytoplasmic matur [...]
atg17 protein networkhttps://string-db.org/network/284812.O42651Autophagy-related protein 17; Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize preautophagosomal structu [...]
caa1 protein networkhttps://string-db.org/network/284812.O42652Aspartate aminotransferase, cytoplasmic; Plays a key role in amino acid metabolism; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
SPAC10F6.14c protein networkhttps://string-db.org/network/284812.O42653ABC1 family protein C10F6.14c; Belongs to the protein kinase superfamily. ADCK protein kinase family.
ric1 protein networkhttps://string-db.org/network/284812.O42656Guanine nucleotide exchange factor subunit ric1; Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the G [...]
grp1 protein networkhttps://string-db.org/network/284812.O42657GRIP and coiled-coil domain-containing protein C27D7.02c.
omt2 protein networkhttps://string-db.org/network/284812.O42658Pterin-4-alpha-carbinolamine dehydratase; Has a role in spore wall formation.
apc14 protein networkhttps://string-db.org/network/284812.O42659Anaphase-promoting complex subunit 14; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through [...]
smd1 protein networkhttps://string-db.org/network/284812.O42661Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site (By similarity).
mtl16 protein networkhttps://string-db.org/network/284812.O42662U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA).
SPAC27D7.09c protein networkhttps://string-db.org/network/284812.O42663Uncharacterized but2-like protein C27D7.09c.
SPAC27D7.11c protein networkhttps://string-db.org/network/284812.O42665Uncharacterized but2-like protein C27D7.11c.
but1 protein networkhttps://string-db.org/network/284812.O42666Uba3-binding protein but1; Acts as a negative regulator of the NEDD8 pathway. Has a role in meiosis.
ssm4 protein networkhttps://string-db.org/network/284812.O42667Microtubule-associated protein ssm4; Binds to nuclear microtubules with the effect of either modifying their structure or function. This then promotes meiotic nuclear division.
tpr1 protein networkhttps://string-db.org/network/284812.O42668Tetratricopeptide repeat protein 1; Involved in promoting potassiumm ion uptake.
rpl1902 protein networkhttps://string-db.org/network/284812.O4269960S ribosomal protein L19-B.
tal1 protein networkhttps://string-db.org/network/284812.O42700Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily.
rpl2102 protein networkhttps://string-db.org/network/284812.O4270660S ribosomal protein L21-B.
emp46 protein networkhttps://string-db.org/network/284812.O42707L-type lectin-like domain-containing protein C4F6.05c.
cdc23 protein networkhttps://string-db.org/network/284812.O42709DNA replication licensing factor mcm10; Required for DNA synthesis. Required for entry into or completion of S phase. Involved in DNA replication and seems to participate in the activation of the [...]
pdh1 protein networkhttps://string-db.org/network/284812.O42826Protein pdh1.
spb1 protein networkhttps://string-db.org/network/284812.O42832AdoMet-dependent rRNA methyltransferase spb1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding m [...]
cut20 protein networkhttps://string-db.org/network/284812.O42839Anaphase-promoting complex subunit 4; Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through m [...]
ted1 protein networkhttps://string-db.org/network/284812.O42841Uncharacterized protein C23A1.02c.
apt1 protein networkhttps://string-db.org/network/284812.O42842Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phospho [...]
tsc3 protein networkhttps://string-db.org/network/284812.O42843Uncharacterized membrane protein C23A1.05.
cmk2 protein networkhttps://string-db.org/network/284812.O42844Calcium/calmodulin-dependent protein kinase type II; Has a role in the regulation of G2/M transition during mitosis; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. [...]
rpl3401 protein networkhttps://string-db.org/network/284812.O4284660S ribosomal protein L34-A.
rbm8 protein networkhttps://string-db.org/network/284812.O42847Uncharacterized RNA-binding protein C23A1.09.
rpl1602 protein networkhttps://string-db.org/network/284812.O4284860S ribosomal protein L16-A.
frs1 protein networkhttps://string-db.org/network/284812.O42849Phenylalanine--tRNA ligase beta subunit.
SPAC23A1.14c protein networkhttps://string-db.org/network/284812.O42851Uncharacterized trans-sulfuration enzyme C23A1.14c.
sec20 protein networkhttps://string-db.org/network/284812.O42852Protein transport protein sec20; SNARE required for targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
rtr1 protein networkhttps://string-db.org/network/284812.O42853Putative RNA polymerase II subunit B1 CTD phosphatase rtr1; Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation. Belon [...]
bbc1 protein networkhttps://string-db.org/network/284812.O42854SH3 domain-containing protein C23A1.17.
mrp51 protein networkhttps://string-db.org/network/284812.O4285537S ribosomal protein mrp51, mitochondrial.
npr2 protein networkhttps://string-db.org/network/284812.O42857Nitrogen permease regulator 2 homolog; Mediates inactivation of the TORC1 complex in response to amino acid starvation. Post-transcriptional regulator of nitrogen permeases (By similarity); Belon [...]
swd1 protein networkhttps://string-db.org/network/284812.O42858Set1 complex component swd1; The Set1 complex specifically methylates 'Lys-4' of histone H3.
mrp2 protein networkhttps://string-db.org/network/284812.O42859Probable 37S ribosomal protein mrp2, mitochondrial.
bub3 protein networkhttps://string-db.org/network/284812.O42860Mitotic checkpoint protein bub3; Involved in cell cycle checkpoint enforcement. Involved in recruitment of checkpoint proteins bub1 and mad3 to the kinetochores, ensuring correct spindle checkpoi [...]
fft3 protein networkhttps://string-db.org/network/284812.O42861ATP-dependent helicase fft3; DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is required for heterochromatin organization. Required for maintaining a hetero [...]
atg14 protein networkhttps://string-db.org/network/284812.O42862Autophagy-related protein 14; Required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific vps34 PI3-kinase complex I. This complex is essential to recruit [...]
oar2 protein networkhttps://string-db.org/network/284812.O428663-oxoacyl-[acyl-carrier-protein] reductase; Involved in biosynthesis of fatty acids in mitochondria. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
ssu72 protein networkhttps://string-db.org/network/284812.O42868RNA polymerase II subunit A C-terminal domain phosphatase ssu72; Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subuni [...]
spa2 protein networkhttps://string-db.org/network/284812.O42869Uncharacterized protein C3G9.05.
frs2 protein networkhttps://string-db.org/network/284812.O42870Phenylalanine--tRNA ligase alpha subunit.
png1 protein networkhttps://string-db.org/network/284812.O42871Chromatin modification-related protein png1; Component of a histone deacetylase complex responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, [...]
rrp41 protein networkhttps://string-db.org/network/284812.O42872Exosome complex component ski6; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrada [...]
pdc201 protein networkhttps://string-db.org/network/284812.O42873Putative pyruvate decarboxylase C3G9.11c.
peg1 protein networkhttps://string-db.org/network/284812.O42874Protein peg1; Microtubule binding protein that regulates the stability of dynamic microtubules. Required for mitotic spindle formation. Belongs to the CLASP family.
msw1 protein networkhttps://string-db.org/network/284812.O42875Tryptophan--tRNA ligase, mitochondrial.
fcf2 protein networkhttps://string-db.org/network/284812.O42877rRNA-processing protein fcf2; Involved in pre-rRNA processing and 40S ribosomal subunit assembly. Required for the early cleavage steps of 35S rRNA at the A(0), A(1), and A(2) sites (By similarit [...]
suc2 protein networkhttps://string-db.org/network/284812.O42878Putative invertase; Belongs to the glycosyl hydrolase 32 family.
SPAC8E11.04c protein networkhttps://string-db.org/network/284812.O42881Acyl-protein thioesterase 1; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates.
SPAC8E11.05c protein networkhttps://string-db.org/network/284812.O42882Uncharacterized protein C8E11.05c.
SPAC8E11.06 protein networkhttps://string-db.org/network/284812.O42883Uncharacterized protein C8E11.06.
pho84 protein networkhttps://string-db.org/network/284812.O42885Putative inorganic phosphate transporter C8E4.01c; High-affinity transporter for external inorganic phosphate. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
SPBC8E4.03 protein networkhttps://string-db.org/network/284812.O42887Putative agmatinase 2; Belongs to the arginase family.
SPBC8E4.04 protein networkhttps://string-db.org/network/284812.O42888Uncharacterized oxidoreductase C8E4.04.
SPBC8E4.05c protein networkhttps://string-db.org/network/284812.O42889Uncharacterized protein C8E4.05c.
cao2 protein networkhttps://string-db.org/network/284812.O42890Copper amine oxidase-like protein cao2; Copper amine oxidase-like protein that does not show any copper amine oxidase activity. May be the appropriate amine substrate for cao2 has not been identi [...]
ntp1 protein networkhttps://string-db.org/network/284812.O42893Neutral trehalase; Belongs to the glycosyl hydrolase 37 family.
rrp46 protein networkhttps://string-db.org/network/284812.O42894Exosome complex component rrp46; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrad [...]
afg1 protein networkhttps://string-db.org/network/284812.O42895Uncharacterized protein C115.02c; Belongs to the AFG1 ATPase family.
SPBC115.03 protein networkhttps://string-db.org/network/284812.O42896Uncharacterized oxidoreductase C115.03; Belongs to the Gfo/Idh/MocA family.
rpn3 protein networkhttps://string-db.org/network/284812.O42897Probable 26S proteasome regulatory subunit rpn3; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
cmt1 protein networkhttps://string-db.org/network/284812.O42898Probable catechol O-methyltransferase 1.
sco1 protein networkhttps://string-db.org/network/284812.O42899Protein sco1; Acts as a copper chaperone, transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2); Belongs to the SCO1/2 family.
vps15 protein networkhttps://string-db.org/network/284812.O42900Serine/threonine-protein kinase ppk19; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
orm1 protein networkhttps://string-db.org/network/284812.O42901Uncharacterized protein C119.09c.
rud3 protein networkhttps://string-db.org/network/284812.O42903GRIP domain-containing protein C119.12.
prp31 protein networkhttps://string-db.org/network/284812.O42904Pre-mRNA-processing factor 31; Required for spliceosome assembly where it is needed to link the U4/U6XU5 tri-snRNP to the prespliceosome complexes. Belongs to the PRP31 family.
rti1 protein networkhttps://string-db.org/network/284812.O42905DNA repair and recombination protein rti1; Active in the repair of DNA damage and in mating-type switching. Probably involved in the repair of DNA double-strands breaks. Has a role in promoting S [...]
npa3 protein networkhttps://string-db.org/network/284812.O42906GPN-loop GTPase 1; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
SPBC119.16c protein networkhttps://string-db.org/network/284812.O42907Uncharacterized protein C119.16c.
cym1 protein networkhttps://string-db.org/network/284812.O42908Mitochondrial presequence protease; ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides (By similarity); Belongs [...]
SPBC16A3.02c protein networkhttps://string-db.org/network/284812.O42909Zinc-type alcohol dehydrogenase-like protein C16A3.02c.
ppr7 protein networkhttps://string-db.org/network/284812.O42910Pentatricopeptide repeat-containing protein 7, mitochondrial; Mitochondrial RNA-binding protein required for the stability of the atp6 mRNA.
rsm25 protein networkhttps://string-db.org/network/284812.O4291137S ribosomal protein S25, mitochondrial.
tad1 protein networkhttps://string-db.org/network/284812.O42912tRNA-specific adenosine deaminase 1; Deaminates adenosine-37 to inosine in tRNA-Ala.
nrm1 protein networkhttps://string-db.org/network/284812.O42913Transcription factor nrm1; Negative regulatory component of the MBF complex involved in cell-cycle-dependent transcription; Belongs to the WHI5/NRM1 family.
oga1 protein networkhttps://string-db.org/network/284812.O42914Uncharacterized protein C16A3.08c.
ufd1 protein networkhttps://string-db.org/network/284812.O42915Ubiquitin fusion degradation protein 1; Functions at a post-ubiquitation step in the ubiquitin fusion degradation (UFD) pathway. It is required for vegetative growth (By similarity).
ale1 protein networkhttps://string-db.org/network/284812.O42916Lysophospholipid acyltransferase; Membrane-bound O-acyltransferase that mediates the incorporation of unsaturated acyl chains into the sn-2 position of phospholipids.
eso1 protein networkhttps://string-db.org/network/284812.O42917N-acetyltransferase eso1; Probable acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only siste [...]
meu7 protein networkhttps://string-db.org/network/284812.O42918Alpha-amylase 4.
SPBC16A3.14 protein networkhttps://string-db.org/network/284812.O42919Putative 37S ribosomal protein S26A, mitochondrial.
coa5 protein networkhttps://string-db.org/network/284812.O42921Mitochondrial protein pet191 homolog; Involved in the assembly of cytochrome c oxidase. Belongs to the PET191 family.
SPBC16A3.17c protein networkhttps://string-db.org/network/284812.O42922Uncharacterized MFS-type transporter C16A3.17c.
cip1 protein networkhttps://string-db.org/network/284812.O42923RNA-binding post-transcriptional regulator cip1; Regulates global gene expression after oxidative stress. Interacts and stabilizes mRNAs and may regulate their transition between different cytopl [...]
eaf7 protein networkhttps://string-db.org/network/284812.O42924Probable chromatin modification-related protein eaf7; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acet [...]
SPBC16C6.01c protein networkhttps://string-db.org/network/284812.O42925Uncharacterized protein C16C6.01c.
vps1302 protein networkhttps://string-db.org/network/284812.O42926Vacuolar protein sorting-associated protein 13b; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family.
rsa1 protein networkhttps://string-db.org/network/284812.O42927Uncharacterized protein C16C6.03c.
dbl6 protein networkhttps://string-db.org/network/284812.O42928Uncharacterized protein C16C6.04.
tma22 protein networkhttps://string-db.org/network/284812.O42929Translation machinery-associated protein 22.
vps10 protein networkhttps://string-db.org/network/284812.O42930Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carb [...]
rpt1 protein networkhttps://string-db.org/network/284812.O4293126S proteasome regulatory subunit 7 homolog; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency a [...]
qcr6 protein networkhttps://string-db.org/network/284812.O42932Cytochrome b-c1 complex subunit 6; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which dr [...]
ogm4 protein networkhttps://string-db.org/network/284812.O42933Dolichyl-phosphate-mannose--protein mannosyltransferase 4; Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. Required for normal cell wall and septum formation.
chp2 protein networkhttps://string-db.org/network/284812.O42934Chromo domain-containing protein 2; Component of the kinetochore which plays a role in stabilizing microtubules and so allowing accurate chromosome segregation.
rpl3201 protein networkhttps://string-db.org/network/284812.O4293560S ribosomal protein L32-B.
las1 protein networkhttps://string-db.org/network/284812.O42936Pre-rRNA-processing protein las1; Required for both pre-rRNA processing and heterochromatic gene silencing.
sec27 protein networkhttps://string-db.org/network/284812.O42937Probable coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate [...]
pfk1 protein networkhttps://string-db.org/network/284812.O42938ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. May also have a role in [...]
uba2 protein networkhttps://string-db.org/network/284812.O42939Ubiquitin-activating enzyme E1-like; The dimeric enzyme acts as a SUMO/pmt3 E1 ligase. It mediates ATP-dependent activation of pmt3 and formation of a thioester with a conserved cysteine residue [...]
snd301 protein networkhttps://string-db.org/network/284812.O42940SRP-independent targeting protein 3 homolog; May function in a SRP (signal recognition particle) and GET (guided entry of tail-anchored proteins) independent pathway for targeting a broad range o [...]
cyp7 protein networkhttps://string-db.org/network/284812.O42941Peptidylprolyl isomerase cyp7; PPIases accelerate the folding of proteins. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing; B [...]
SPBC16H5.08c protein networkhttps://string-db.org/network/284812.O42943Uncharacterized ABC transporter ATP-binding protein C16H5.08c.
omh2 protein networkhttps://string-db.org/network/284812.O42944O-glycoside alpha-1,2-mannosyltransferase homolog 2; Probable mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins; Belongs to the glycosyltransferase 15 family.
prp43 protein networkhttps://string-db.org/network/284812.O42945Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA.
SPBC16H5.12c protein networkhttps://string-db.org/network/284812.O42947Uncharacterized protein C16H5.12c.
wdr7 protein networkhttps://string-db.org/network/284812.O42948Uncharacterized WD repeat-containing protein C16H5.13.
abz2 protein networkhttps://string-db.org/network/284812.O42951Putative aminodeoxychorismate lyase; Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate.
SPBC19G7.04 protein networkhttps://string-db.org/network/284812.O42953HMG box-containing protein C19G7.04.
mbx1 protein networkhttps://string-db.org/network/284812.O42954MADS-box transcription factor 1; Acts as a transcriptional activator with a role in the regulation of mitosis. Regulates septation and the periodic transcription of cdc15.
ppr3 protein networkhttps://string-db.org/network/284812.O42955Pentatricopeptide repeat-containing protein 3, mitochondrial; RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability [...]
art1 protein networkhttps://string-db.org/network/284812.O42956Arrestin family protein 1; Involved in cytokinesis; Belongs to the arrestin family.
ulp1 protein networkhttps://string-db.org/network/284812.O42957Ubiquitin-like-specific protease 1; A cysteine protease that proteolytically removes the C- terminus of pmt3.
pdc2 protein networkhttps://string-db.org/network/284812.O42958DNA topoisomerase 2-associated protein pat1; Activator of decapping that functions as a general and active mechanism of translational repression and required for P-body formation. Stabilizes the [...]
cog5 protein networkhttps://string-db.org/network/284812.O42962Conserved oligomeric Golgi complex subunit 5; Acts as essential component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Gol [...]
nup44 protein networkhttps://string-db.org/network/284812.O42963Nucleoporin nup44; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components [...]
iws1 protein networkhttps://string-db.org/network/284812.O42964Transcription factor iws1; Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post- recruitment and recruitment steps of transcription (By [...]
sec6102 protein networkhttps://string-db.org/network/284812.O42965Uncharacterized protein C19G7.17.
SPBC1E8.02 protein networkhttps://string-db.org/network/284812.O42967Uncharacterized ubiquitin-like protein C1E8.02.
SPBC1E8.03c protein networkhttps://string-db.org/network/284812.O42968Uncharacterized protein C1E8.03c.
knh4 protein networkhttps://string-db.org/network/284812.O42970Uncharacterized serine-rich protein C1E8.05.
apc10 protein networkhttps://string-db.org/network/284812.O42971Anaphase-promoting complex subunit 10; Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through [...]
SPBC20F10.02c protein networkhttps://string-db.org/network/284812.O42972UPF0588 membrane protein C20F10.02c.
SPBC20F10.03 protein networkhttps://string-db.org/network/284812.O42973Uncharacterized protein C20F10.03.
nrl1 protein networkhttps://string-db.org/network/284812.O42975Protein NRDE2 homolog; Belongs to the NRDE2 family.
ltc1 protein networkhttps://string-db.org/network/284812.O42976Uncharacterized membrane protein C20F10.07.
lsm5 protein networkhttps://string-db.org/network/284812.O42978U6 snRNA-associated Sm-like protein LSm5; Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. LSm5 is required for processing of [...]
psl1 protein networkhttps://string-db.org/network/284812.O42979PHO85 cyclin-like protein psl1; Cyclin partner of the cyclin-dependent kinase (CDK) pef1 (PHO85 homolog).
nep1 protein networkhttps://string-db.org/network/284812.O42980NEDD8-specific protease 1; Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted protei [...]
rps1701 protein networkhttps://string-db.org/network/284812.O4298440S ribosomal protein S17-A.
rpl1601 protein networkhttps://string-db.org/network/284812.O4299160S ribosomal protein L16-B.
fkh1 protein networkhttps://string-db.org/network/284812.O42993Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Has an important role i [...]
mis19 protein networkhttps://string-db.org/network/284812.O42995CENP-A recruiting complex protein mis19; Component of the CENP-A recruiting complex that ensures the integrity of mitotic spindles through maintenance of kinetochore factors mis6/CENP-I and cnp1/ [...]
SPBC27B12.05 protein networkhttps://string-db.org/network/284812.O42996Uncharacterized WD repeat-containing protein C27B12.05.
SPBC27B12.07 protein networkhttps://string-db.org/network/284812.O42997Uncharacterized protein C27B12.07.
sip1 protein networkhttps://string-db.org/network/284812.O42998Pof6 interactor protein 1; Required for endocytosis. Also involved in cytokinesis and cell division.
tom7 protein networkhttps://string-db.org/network/284812.O42999Mitochondrial import receptor subunit tom7; Belongs to the Tom7 family.
liz1 protein networkhttps://string-db.org/network/284812.O43000Pantothenate transporter liz1; Transports pantothenate into the cell. Belongs to the major facilitator superfamily. Allantoate permease family.
syj1 protein networkhttps://string-db.org/network/284812.O43001Inositol-1,4,5-trisphosphate 5-phosphatase 1; Controls the cellular levels and subcellular distribution of phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5- bisphosphate. Involved in [...]
sbh1 protein networkhttps://string-db.org/network/284812.O43002Protein transport protein sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
mmf1 protein networkhttps://string-db.org/network/284812.O43003Protein mmf1, mitochondrial; Plays a role in the maintenance of mitochondrial DNA. Belongs to the RutC family.
rpl1603 protein networkhttps://string-db.org/network/284812.O4300460S ribosomal protein L16-C.
apl1 protein networkhttps://string-db.org/network/284812.O43005AP-2 complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact wit [...]
mug178 protein networkhttps://string-db.org/network/284812.O43006Meiotically up-regulated gene 178 protein; Has a role in meiosis.
ade9 protein networkhttps://string-db.org/network/284812.O43007C-1-tetrahydrofolate synthase, mitochondrial; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family.
crs1 protein networkhttps://string-db.org/network/284812.O43008Meiosis-specific cyclin crs1; Has a role in meiotic chromosome segregation. Belongs to the cyclin family. Cyclin AB subfamily.
mug110 protein networkhttps://string-db.org/network/284812.O43009Meiotically up-regulated gene 110 protein; Has a role in meiosis.
myr1 protein networkhttps://string-db.org/network/284812.O43010Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family.
hrs1 protein networkhttps://string-db.org/network/284812.O43011Histidine--tRNA ligase, mitochondrial; Catalyzes the aminoacylation of histidyl-tRNA in both the cytoplasm and the mitochondrion.
dcd1 protein networkhttps://string-db.org/network/284812.O43012Deoxycytidylate deaminase; Supplies the nucleotide substrate for thymidylate synthetase. Belongs to the cytidine and deoxycytidylate deaminase family.
csi1 protein networkhttps://string-db.org/network/284812.O43013Uncharacterized protein C2G2.14.
mpi1 protein networkhttps://string-db.org/network/284812.O43014Mannose-6-phosphate isomerase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
psu2 protein networkhttps://string-db.org/network/284812.O43015Probable secreted beta-glucosidase C2G2.17c; Cell surface beta-glucosidase involved in cell wall biogenesis; Belongs to the SUN family.
swd3 protein networkhttps://string-db.org/network/284812.O43017Set1 complex component swd3; The Set1 complex specifically methylates 'Lys-4' of histone H3.
SPBC354.04 protein networkhttps://string-db.org/network/284812.O43018Uncharacterized protein C354.04.
sre2 protein networkhttps://string-db.org/network/284812.O43019Putative transcription factor sre2; Putative transcription factor.
mrps16 protein networkhttps://string-db.org/network/284812.O43020Probable 37S ribosomal protein S16, mitochondrial.
osh42 protein networkhttps://string-db.org/network/284812.O43021Oxysterol-binding protein homolog C354.07c.
rsn1 protein networkhttps://string-db.org/network/284812.O43022Uncharacterized protein C354.08c; Acts as an osmosensitive calcium-permeable cation channel. Belongs to the CSC1 (TC 1.A.17) family.
tre1 protein networkhttps://string-db.org/network/284812.O43023Inactive zinc metalloprotease C354.09c.
def1 protein networkhttps://string-db.org/network/284812.O43024CUE domain-containing protein C354.10.
gpd3 protein networkhttps://string-db.org/network/284812.O43026Glyceraldehyde-3-phosphate dehydrogenase 2; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
rga6 protein networkhttps://string-db.org/network/284812.O43027Probable Rho-GTPase-activating protein 6.
vac8 protein networkhttps://string-db.org/network/284812.O43028Vacuolar protein 8; Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole; Belongs to the beta-catenin family.
fap1 protein networkhttps://string-db.org/network/284812.O43029L-pipecolate oxidase; Oxidizes L-pipecolate and L-proline (6,7% of the activity for L-pipecolate); Belongs to the MSOX/MTOX family.
fes1 protein networkhttps://string-db.org/network/284812.O43030Hsp70 nucleotide exchange factor fes1; Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated foldi [...]
cwf28 protein networkhttps://string-db.org/network/284812.O43031Pre-mRNA-splicing factor cwf28; Involved in spliceosome maturation and the first step of pre- mRNA splicing.
srp101 protein networkhttps://string-db.org/network/284812.O43032Signal recognition particle receptor subunit alpha homolog; Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct [...]
oms1 protein networkhttps://string-db.org/network/284812.O43033Uncharacterized methyltransferase C3B9.04, mitochondrial; Probable methyltransferase; Belongs to the methyltransferase superfamily. METL family.
hot15 protein networkhttps://string-db.org/network/284812.O43034Uncharacterized protein C3B9.05.
atg3 protein networkhttps://string-db.org/network/284812.O43035Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) [...]
rpa43 protein networkhttps://string-db.org/network/284812.O43036DNA-directed RNA polymerase I subunit rpa43; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
mnh1 protein networkhttps://string-db.org/network/284812.O43037Protein mago nashi homolog.
vps36 protein networkhttps://string-db.org/network/284812.O43038Vacuolar protein-sorting-associated protein 36; Component of the ESCRT-II complex, which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The [...]
ctf1 protein networkhttps://string-db.org/network/284812.O43040Cleavage and termination factor 1; Component of the cleavage factor I (CF I) involved in pre- mRNA 3'-end processing.
trs23 protein networkhttps://string-db.org/network/284812.O43041Transport protein particle subunit trs23; TRAPP plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.
mrpl3 protein networkhttps://string-db.org/network/284812.O4304254S ribosomal protein L3, mitochondrial; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL44 subfamily.
scp1 protein networkhttps://string-db.org/network/284812.O43043Sterol regulatory element-binding protein cleavage-activating protein; Escort protein required for sre1 processing at low sterol as well as oxygen levels. May regulate export of the scp1/sre1 com [...]
nup120 protein networkhttps://string-db.org/network/284812.O43044Nucleoporin nup120; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural component [...]
isa2 protein networkhttps://string-db.org/network/284812.O43045Iron-sulfur assembly protein 2; Involved in the assembly of mitochondrial and cytoplasmic iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly (By si [...]
vma7 protein networkhttps://string-db.org/network/284812.O43046V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracell [...]
mge1 protein networkhttps://string-db.org/network/284812.O43047GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitoc [...]
SPBC3F6.01c protein networkhttps://string-db.org/network/284812.O43049Serine/threonine-protein phosphatase T; Protein phosphatase that specifically binds to and dephosphorylates the molecular chaperone Hsp90. Dephosphorylation positively regulates the Hsp90 chapero [...]
erg26 protein networkhttps://string-db.org/network/284812.O43050Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family.
nop14 protein networkhttps://string-db.org/network/284812.O43051Probable nucleolar complex protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity).
rga1 protein networkhttps://string-db.org/network/284812.O43052Rho-type GTPase-activating protein 1; GTPase-activating protein for Rho1. Involved in the F-actin patch localization, cell morphogenesis, regulation of septation, and cell wall synthesis.
alg6 protein networkhttps://string-db.org/network/284812.O43053Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers gluco [...]
thr1 protein networkhttps://string-db.org/network/284812.O43056Probable homoserine kinase.
dss4 protein networkhttps://string-db.org/network/284812.O43057Guanine nucleotide exchange factor MSS4 homolog; Guanine-nucleotide-releasing protein that acts on members of the sec4/ypt1/rab subfamily.
sep1 protein networkhttps://string-db.org/network/284812.O43058Forkhead protein sep1; Required for promoter sequence element PCB-driven, M-phase- specific transcription. Acts as a transcriptional activator with a role in the regulation of mitosis. Regulates [...]
syp1 protein networkhttps://string-db.org/network/284812.O43059Cytoskeletal protein syp1; Multi-functional protein that contributes to the endocytic process, but also to events that occur at the neck during cytokinesis. Plays a role as an endocytic adapters [...]
tif306 protein networkhttps://string-db.org/network/284812.O43060Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoi [...]
otg2 protein networkhttps://string-db.org/network/284812.O43061Meiotically up-regulated gene 136 protein; Has a role in meiosis.
otg3 protein networkhttps://string-db.org/network/284812.O43062Uncharacterized protein C4C3.09.
pre3 protein networkhttps://string-db.org/network/284812.O43063Probable proteasome subunit beta type-1; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent t [...]
mot1 protein networkhttps://string-db.org/network/284812.O43065Probable helicase mot1; Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box via its ATPase activity (By similarity).
ppk30 protein networkhttps://string-db.org/network/284812.O43066Serine/threonine-protein kinase ppk30.
pal2 protein networkhttps://string-db.org/network/284812.O43067Uncharacterized protein C6B1.03c.
mde4 protein networkhttps://string-db.org/network/284812.O43068Monopolin complex subunit mde4; The monopolin-like pcs1/mde4 complex is essential for accurate chromosome segregation during mitosis and meiosis II. May clamp together microtubule binding sites o [...]
atg7 protein networkhttps://string-db.org/network/284812.O43069Ubiquitin-like modifier-activating enzyme atg7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates atg12 [...]
nbs1 protein networkhttps://string-db.org/network/284812.O43070DNA repair and telomere maintenance protein nbs1; Required for DNA damage repair and S-phase DNA damage checkpoint. Involved in telomere length maintenance and maintenance of chromatin structure.
prp17 protein networkhttps://string-db.org/network/284812.O43071Pre-mRNA-processing factor 17; Functions in the second step of pre-mRNA splicing. Involved in splicing intron which are longer than 200 nucleotides.
vps68 protein networkhttps://string-db.org/network/284812.O43073UPF0220 protein C8D2.02c.
tac1 protein networkhttps://string-db.org/network/284812.O43075Probable transcriptional regulatory protein C8D2.12c.
shq1 protein networkhttps://string-db.org/network/284812.O43076Protein shq1; Involved in the early biogenesis steps of box H/ACA snoRNP assembly; Belongs to the SHQ1 family.
mde3 protein networkhttps://string-db.org/network/284812.O43077Sporulation protein kinase mde3; Protein kinase which is essential for spore formation.
knk1 protein networkhttps://string-db.org/network/284812.O43078ATPase-like fidgetin.
apl2 protein networkhttps://string-db.org/network/284812.O43079AP-1 complex subunit beta-1; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact w [...]
naa38 protein networkhttps://string-db.org/network/284812.O43080N-alpha-acetyltransferase 38, NatC auxiliary subunit.
SPBC947.06c protein networkhttps://string-db.org/network/284812.O43081Uncharacterized MFS-type transporter C947.06c.
rrp1402 protein networkhttps://string-db.org/network/284812.O43082Ribosomal RNA-processing protein 14-C; Involved in ribosome biogenesis and cell polarity. Required for the synthesis of both 40S and 60S ribosomal subunits and may also play some direct role in c [...]
hip4 protein networkhttps://string-db.org/network/284812.O43083Histone promoter control protein 2; Component of the HIR complex, which functions as a histone chaperone that cooperates with cia1/asf1 to promote replication- independent chromatin assembly.
hsp3103 protein networkhttps://string-db.org/network/284812.O43084Probable glutathione-independent glyoxalase hsp3103; Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step. May play a role in detoxifying end [...]
dsc1 protein networkhttps://string-db.org/network/284812.O43085DSC E3 ubiquitin ligase complex subunit 1; Catalytic component of the DSC E3 ubiquitin ligase complex which is required for the sre1 transcriptional activator proteolytic cleavage to release the [...]
elg1 protein networkhttps://string-db.org/network/284812.O43086Telomere length regulation protein elg1; Involved in the negative control of telomere length and in telomeric silencing through a replication-mediated pathway. May have a role in Okazaki fragment [...]
kms2 protein networkhttps://string-db.org/network/284812.O43087Karyogamy meiotic segregation protein 2.
rba50 protein networkhttps://string-db.org/network/284812.O43088RNA polymerase II-associated protein rba50; Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II [...]
cbp6 protein networkhttps://string-db.org/network/284812.O43089Cytochrome B pre-mRNA-processing protein 6; Involved in processing of the 5' terminus and the intervening sequences of cytochrome b pre-mRNA.
ndi1 protein networkhttps://string-db.org/network/284812.O43090Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial; Catalyzes the oxidation of NADH.
dps1 protein networkhttps://string-db.org/network/284812.O43091Decaprenyl-diphosphate synthase subunit 1; Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10; Belongs to the FPP/GGPP synthase family.
oxa102 protein networkhttps://string-db.org/network/284812.O43092Mitochondrial inner membrane protein oxa1-2; Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome [...]
orc5 protein networkhttps://string-db.org/network/284812.O43114Origin recognition complex subunit 5; Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcript [...]
uap2 protein networkhttps://string-db.org/network/284812.O43120Splicing factor U2AF-associated protein 2; Has a role in pre-mRNA splicing. Belongs to the HTATSF1 family.
lsb1 protein networkhttps://string-db.org/network/284812.O43125Protein csh3.
ccc2 protein networkhttps://string-db.org/network/284812.O59666Copper-transporting ATPase ccc2; Probably involved in copper transport and in the regulation of cellular copper level. Retrieves copper from the metallochaperone atx1 and incorporates it into tra [...]
his7 protein networkhttps://string-db.org/network/284812.O59667Histidine biosynthesis bifunctional protein his7.
gid2 protein networkhttps://string-db.org/network/284812.O59668LisH domain-containing protein C29A3.03c.
vps71 protein networkhttps://string-db.org/network/284812.O59669SWR1 complex subunit vps71; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected gen [...]
sap14 protein networkhttps://string-db.org/network/284812.O59670Splicing factor 3B subunit 6-like protein; Necessary for the splicing of pre-mRNA.
pof4 protein networkhttps://string-db.org/network/284812.O59671Elongin-A.
gcn20 protein networkhttps://string-db.org/network/284812.O59672Uncharacterized ABC transporter ATP-binding protein C29A3.09c.
atp14 protein networkhttps://string-db.org/network/284812.O59673ATP synthase subunit H, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
ort1 protein networkhttps://string-db.org/network/284812.O59674Uncharacterized mitochondrial carrier C29A3.11c.
rps902 protein networkhttps://string-db.org/network/284812.O5967540S ribosomal protein S9-B; Belongs to the universal ribosomal protein uS4 family.
pdp1 protein networkhttps://string-db.org/network/284812.O59676PWWP domain-containing protein 1; Necessary for DNA damage checkpoint activation. Required for the association of set9 with chromatin and subsequent methylation of H4K20. Associates with H4K20me1 [...]
rsm23 protein networkhttps://string-db.org/network/284812.O5967737S ribosomal protein S23, mitochondrial; Required for maintenance of mitochondrial DNA.
rrs1 protein networkhttps://string-db.org/network/284812.O59678Ribosome biogenesis regulatory protein homolog; Involved in ribosomal large subunit assembly.
gef3 protein networkhttps://string-db.org/network/284812.O59679Rho guanine nucleotide exchange factor gef3; Has a role in the control of cell polarity and cytokinesis. Involved in bipolar growth and septum formation.
cyt1 protein networkhttps://string-db.org/network/284812.O59680Cytochrome c1, heme protein, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain [...]
SPBC18E5.01 protein networkhttps://string-db.org/network/284812.O59681Uncharacterized protein C18E5.01; Belongs to the cycloisomerase 2 family.
lcb1 protein networkhttps://string-db.org/network/284812.O59682Serine palmitoyltransferase 1; Component of serine palmitoyltransferase (SPT), which catalyzes the committed step in the synthesis of sphingolipids, the condensation of serine with palmitoyl CoA [...]
mti2 protein networkhttps://string-db.org/network/284812.O59683Translation initiation factor IF-2, mitochondrial; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes [...]
ppk25 protein networkhttps://string-db.org/network/284812.O59697Serine/threonine-protein kinase ppk25.
SPBC36.02c protein networkhttps://string-db.org/network/284812.O59699Uncharacterized transporter C36.02c.
mfs3 protein networkhttps://string-db.org/network/284812.O59700Uncharacterized transporter C36.03c.
cys11 protein networkhttps://string-db.org/network/284812.O59701Cysteine synthase 1; Catalyzes the conversion of O-succinyl-L-serine into cysteine, the last step in the cysteine biosynthesis pathway. Can also use O-acetyl-L-serine ; Belongs to the cysteine sy [...]
clr6 protein networkhttps://string-db.org/network/284812.O59702Histone deacetylase clr6; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic [...]
spo9 protein networkhttps://string-db.org/network/284812.O59703Geranylgeranyl pyrophosphate synthase; Catalyzes the trans-addition of the 3 molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate. Required for the membrane attachment of ypt7 and rhb [...]
elp1 protein networkhttps://string-db.org/network/284812.O59704Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in trans [...]
cog2 protein networkhttps://string-db.org/network/284812.O59705Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function.
sap61 protein networkhttps://string-db.org/network/284812.O59706Pre-mRNA-splicing factor sap61; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
ups2 protein networkhttps://string-db.org/network/284812.O59707UPS-like protein C36.10; Required for mitochondrial morphology. May control phospholipid metabolism in the mitochondrial intermembrane space (By similarity); Belongs to the slowmo family.
SPBC36.11 protein networkhttps://string-db.org/network/284812.O59708Uncharacterized protein C36.11.
git7 protein networkhttps://string-db.org/network/284812.O59709Glucose-insensitive transcription protein 7; Involved in cyclic AMP (cAMP) pathway, possibly by participating in the assembly or the conformational activation of specific multiprotein complexes.
arh1 protein networkhttps://string-db.org/network/284812.O59710Probable NADPH:adrenodoxin oxidoreductase, mitochondrial; Serves as the first electron transfer protein in all the mitochondrial P450 systems.
lys9 protein networkhttps://string-db.org/network/284812.O59711Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]; Belongs to the saccharopine dehydrogenase family.
plt1 protein networkhttps://string-db.org/network/284812.O59712Uncharacterized transporter C3B8.04c.
dph1 protein networkhttps://string-db.org/network/284812.O597132-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidi [...]
SPBC3B8.06 protein networkhttps://string-db.org/network/284812.O59714Uncharacterized membrane protein C3B8.06.
dsd1 protein networkhttps://string-db.org/network/284812.O59715Sphingolipid delta(4)-desaturase; Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides. Required for sphingosine biosynthesis.
SPBC3B8.08 protein networkhttps://string-db.org/network/284812.O59716Uncharacterized protein C3B8.8.
nem1 protein networkhttps://string-db.org/network/284812.O59718Nuclear envelope morphology protein 1; Catalytic component of the nem1-spo7 complex which acts as a phosphatase and may be required for proper nuclear membrane morphology.
rrn6 protein networkhttps://string-db.org/network/284812.O59719Uncharacterized protein C3B8.11.
pus4 protein networkhttps://string-db.org/network/284812.O59721tRNA pseudouridine synthase 4; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. Also catalyzes pseudouridylation of mRNAs with the consensus sequence [...]
fab1 protein networkhttps://string-db.org/network/284812.O597221-phosphatidylinositol 3-phosphate 5-kinase fab1; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarit [...]
mic60 protein networkhttps://string-db.org/network/284812.O59725MICOS complex subunit mic60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner mem [...]
fnx2 protein networkhttps://string-db.org/network/284812.O59726Vacuolar membrane amino acid uptake transporter fnx2; MFS-type transporter involved in vacuolar amino acid uptake. Belongs to the major facilitator superfamily.
SPBC3E7.07c protein networkhttps://string-db.org/network/284812.O59727Protein PBDC1 homolog.
SPBC3E7.09 protein networkhttps://string-db.org/network/284812.O59729Uncharacterized protein slp1; May be involved in membrane protein folding.
fma1 protein networkhttps://string-db.org/network/284812.O59730Methionine aminopeptidase 1; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence [...]
SPBC3E7.11c protein networkhttps://string-db.org/network/284812.O59731Uncharacterized J domain-containing protein C3E7.11c.
cfh4 protein networkhttps://string-db.org/network/284812.O59732Chitin synthase regulatory factor 1; Involved in chitin biosynthesis.
syf2 protein networkhttps://string-db.org/network/284812.O59733Pre-mRNA-splicing factor syf2; Involved in pre-mRNA splicing.
smf1 protein networkhttps://string-db.org/network/284812.O59734Small nuclear ribonucleoprotein F; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site (By similarity).
lac1 protein networkhttps://string-db.org/network/284812.O59735Sphingosine N-acyltransferase lac1; Component of the ceramide synthase complex required for C26- CoA-dependent ceramide synthesis. Facilitates ER-to-Golgi transport of GPI-anchored proteins (By s [...]
leu3 protein networkhttps://string-db.org/network/284812.O597362-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isoprop [...]
gyp1 protein networkhttps://string-db.org/network/284812.O59737GTPase-activating protein gyp1; Stimulates specifically the GTPase activity of ypt1. Functions on the Golgi as a negative regulator of ypt1 (By similarity).
SPBC530.02 protein networkhttps://string-db.org/network/284812.O59738Uncharacterized transporter C530.02.
bag102 protein networkhttps://string-db.org/network/284812.O59739BAG family molecular chaperone regulator 1B; Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.
mod5 protein networkhttps://string-db.org/network/284812.O59740Cell polarity protein mod5; With tea1, acts in a positive-feedback loop in the microtubule-mediated regulation of cell polarity. Involved in the anchoring of tea1 at the cortex as well as the cor [...]
prt1 protein networkhttps://string-db.org/network/284812.O59741Uncharacterized transcriptional regulatory protein C530.05.
clu1 protein networkhttps://string-db.org/network/284812.O59742Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
SPBC530.07c protein networkhttps://string-db.org/network/284812.O59743Uncharacterized protein C530.07c.
mrl1 protein networkhttps://string-db.org/network/284812.O59745Putative mannose 6-phosphate receptor-like protein C530.09c.
SPBC530.11c protein networkhttps://string-db.org/network/284812.O59746Uncharacterized transcriptional regulatory protein C530.11c.
pdf1 protein networkhttps://string-db.org/network/284812.O59747Palmitoyl-protein thioesterase-dolichyl pyrophosphate phosphatase fusion 1; Essential protein. Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in prot [...]
lsc1 protein networkhttps://string-db.org/network/284812.O59748CTD kinase subunit beta; Cyclin subunit of the CTDK-I complex, which hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit. As part of the C [...]
klp6 protein networkhttps://string-db.org/network/284812.O59751Kinesin-like protein 6; Has a role in establishing metaphase during mitosis. Required for chromosome segregation where it generates tension during kinetochore capturing; Belongs to the TRAFAC cla [...]
rhp14 protein networkhttps://string-db.org/network/284812.O59753DNA repair protein rad14; Involved in nucleotide excision repair (NER). Functional in repair of ultraviolet radiation induced damages and in mitotic mutation avoidance. Binds damaged DNA. Binds s [...]
cut12 protein networkhttps://string-db.org/network/284812.O59755Spindle pole body-associated protein cut12; Required for bipolar spindle formation. May act as a regulator of the p34cdc2/cyclin B kinase. Required for full activation of the plo1 kinase. However [...]
spc7 protein networkhttps://string-db.org/network/284812.O59757Kinetochore protein spc7; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycl [...]
mmt1 protein networkhttps://string-db.org/network/284812.O59758Uncharacterized metal transporter C1020.03.
dcr2 protein networkhttps://string-db.org/network/284812.O59759Uncharacterized protein C1020.05.
SPCC1020.07 protein networkhttps://string-db.org/network/284812.O59760Putative uncharacterized hydrolase C1020.07.
tyw1 protein networkhttps://string-db.org/network/284812.O59761S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found [...]
gnr1 protein networkhttps://string-db.org/network/284812.O59762Guanine nucleotide-binding protein negative regulator 1; Negatively regulates the pheromone-response pathway. Acts as a structural mimic of the G protein beta subunit thereby interacting with gpa [...]
oca2 protein networkhttps://string-db.org/network/284812.O59763Serine/threonine-protein kinase oca2; Overexpression causes cell cycle arrest. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
emc6 protein networkhttps://string-db.org/network/284812.O59764ER membrane protein complex subunit 6.
mad3 protein networkhttps://string-db.org/network/284812.O59767Mitotic spindle checkpoint component mad3; Has a role in transducing the anaphase inhibitory signal to the anaphase promoting complex (APC). Forms part of the mad2 feedback control.
vcx1 protein networkhttps://string-db.org/network/284812.O59768Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in [...]
pre10 protein networkhttps://string-db.org/network/284812.O59770Probable proteasome subunit alpha type-7; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent [...]
ura6 protein networkhttps://string-db.org/network/284812.O59771Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preferenc [...]
sws2 protein networkhttps://string-db.org/network/284812.O5977237S ribosomal protein subunit sws2, mitochondrial; Belongs to the universal ribosomal protein uS13 family.
vid21 protein networkhttps://string-db.org/network/284812.O59773Chromatin modification-related protein vid21; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation [...]
yps1 protein networkhttps://string-db.org/network/284812.O59774Aspartic proteinase yapsin-1; Cleaves at paired basic residues. Belongs to the peptidase A1 family.
bio2 protein networkhttps://string-db.org/network/284812.O59778Biotin synthase; Belongs to the radical SAM superfamily. Biotin synthase family.
SPCC1235.01 protein networkhttps://string-db.org/network/284812.O59779Uncharacterized protein C1235.01.
SPCC320.03 protein networkhttps://string-db.org/network/284812.O59780Uncharacterized transcriptional regulatory protein C320.03.
gem1 protein networkhttps://string-db.org/network/284812.O59781Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
SPCC320.05 protein networkhttps://string-db.org/network/284812.O59782Probable sulfate permease C320.05; Possible sulfate transporter; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
mde7 protein networkhttps://string-db.org/network/284812.O59784RNA-binding protein mde7.
SPCC320.08 protein networkhttps://string-db.org/network/284812.O59785Uncharacterized solute carrier family 35 member C320.08.
hem15 protein networkhttps://string-db.org/network/284812.O59786Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
srp72 protein networkhttps://string-db.org/network/284812.O59787Signal recognition particle subunit srp72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA on [...]
ark1 protein networkhttps://string-db.org/network/284812.O59790Serine/threonine-protein kinase ark1; Required for the spindle checkpoint attachment response during spindle formation, kinetochore microtubule interactions and chromosome segregation during anap [...]
sry1 protein networkhttps://string-db.org/network/284812.O59791Serine racemase; Catalyzes the synthesis of D-serine from L-serine. Has dehydratase activity towards both L-serine and D-serine.
cif1 protein networkhttps://string-db.org/network/284812.O59792Calnexin-independence factor 1; Induces a stably inheritable state of calnexin independence called the Cin state when overexpressed.
bis1 protein networkhttps://string-db.org/network/284812.O59793Stress response protein bis1; Has a role in maintaining cell viability during stationary phase induced by stress response. May be involved in pre-mRNA splicing; Belongs to the ESS2 family.
rpl1702 protein networkhttps://string-db.org/network/284812.O5979460S ribosomal protein L17-B.
coy1 protein networkhttps://string-db.org/network/284812.O59795Protein CASP; May be involved in intra-Golgi transport; Belongs to the CASP family.
vps3 protein networkhttps://string-db.org/network/284812.O59796Vacuolar protein sorting-associated protein 3; Required for sorting and processing of soluble vacuolar proteins; Belongs to the VPS3 family.
nap1 protein networkhttps://string-db.org/network/284812.O59797Putative nucleosome assembly protein C364.06; Belongs to the nucleosome assembly protein (NAP) family.
cwf5 protein networkhttps://string-db.org/network/284812.O59800Pre-mRNA-splicing factor cwf5; Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA (By similarity). Involved in pre-mRNA splicing; [...]
ski2 protein networkhttps://string-db.org/network/284812.O59801Putative ATP-dependent RNA helicase C550.03c; RNA helicase component of the SKI complex involved in 3'-mRNA degradation pathway.
gpi2 protein networkhttps://string-db.org/network/284812.O59802Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the fi [...]
hsp10 protein networkhttps://string-db.org/network/284812.O5980410 kDa heat shock protein, mitochondrial; Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppr [...]
fah2 protein networkhttps://string-db.org/network/284812.O59805Putative amidase C550.07; Belongs to the amidase family.
SPCC550.08 protein networkhttps://string-db.org/network/284812.O59806Uncharacterized N-acetyltransferase C550.08.
pex32 protein networkhttps://string-db.org/network/284812.O59807Peroxisomal membrane protein pex32.
atd3 protein networkhttps://string-db.org/network/284812.O59808Probable betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
nmd5 protein networkhttps://string-db.org/network/284812.O59809Probable importin c550.11; Active in protein import into the nucleus.
vgl1 protein networkhttps://string-db.org/network/284812.O59810Vigilin 1; Required for cell survival under thermal stress.
rei1 protein networkhttps://string-db.org/network/284812.O59811Cytoplasmic 60S subunit biogenesis factor SPCC550.15c; Pre-60S-associated factor involved in the cytoplasmic maturation of the 60S subunit. Involved in the dissociation and recycling of other lat [...]
gcd1 protein networkhttps://string-db.org/network/284812.O59812Probable glucose-6-phosphate 1-dehydrogenase C794.01c; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrate [...]
SPCC794.03 protein networkhttps://string-db.org/network/284812.O59813Uncharacterized amino-acid permease C794.03.
SPCC794.04c protein networkhttps://string-db.org/network/284812.O59814Uncharacterized transporter C794.04c.
SPCC794.06 protein networkhttps://string-db.org/network/284812.O59815Putative malic acid transport protein.
lat1 protein networkhttps://string-db.org/network/284812.O59816Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains mult [...]
efr3 protein networkhttps://string-db.org/network/284812.O59817Protein efr3; Belongs to the EFR3 family.
ugp1 protein networkhttps://string-db.org/network/284812.O59819Probable UTP--glucose-1-phosphate uridylyltransferase; Plays a central role as a glucosyl donor in cellular metabolic pathways.
csl4 protein networkhttps://string-db.org/network/284812.O59821Exosome complex component csl4; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrada [...]
vma8 protein networkhttps://string-db.org/network/284812.O59823V-type proton ATPase subunit D; Subunit of the peripheral V1 complex of vacuolar ATPase. V- ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus [...]
yme1 protein networkhttps://string-db.org/network/284812.O59824ATP-dependent zinc metalloprotease YME1 homolog; Putative ATP-dependent protease; In the C-terminal section; belongs to the peptidase M41 family.
thp1 protein networkhttps://string-db.org/network/284812.O59825G/U mismatch-specific uracil DNA glycosylase; Removes uracil from G/U mispairs in ssDNA. Also corrects G/G mispairs. Does not catalyze the removal of thymine from G/T mispairs.
osr2 protein networkhttps://string-db.org/network/284812.O59826Putative voltage-gated potassium channel subunit beta; Probable accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.
gst2 protein networkhttps://string-db.org/network/284812.O59827Glutathione S-transferase 2; Involved in the oxidative stress response and detoxification.
alr1 protein networkhttps://string-db.org/network/284812.O59828Alanine racemase, catabolic; Belongs to the alanine racemase family.
SPCC965.09 protein networkhttps://string-db.org/network/284812.O59829Probable nitrilase C965.09.
SPCC965.10 protein networkhttps://string-db.org/network/284812.O59830Uncharacterized transcriptional regulatory protein C965.10.
agp3 protein networkhttps://string-db.org/network/284812.O59831Uncharacterized amino-acid permease C965.11c.
dpe2 protein networkhttps://string-db.org/network/284812.O59832Uncharacterized dipeptidase C965.12; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
SPCC965.13 protein networkhttps://string-db.org/network/284812.O59833Uncharacterized transporter C965.13.
SPCC965.14c protein networkhttps://string-db.org/network/284812.O59834Probable cytosine deaminase; Converts cytosine to uracil or 5-methylcytosine to thymine by deaminating carbon number 4; Belongs to the cytidine and deoxycytidylate deaminase family.
cdm1 protein networkhttps://string-db.org/network/284812.O59835DNA polymerase delta subunit 4; Appears to have a role in the stabilization of the DNA polymerase delta complex.
dfp1 protein networkhttps://string-db.org/network/284812.O59836Hsk1-interacting molecule 1; Activates hsk1 kinase and is essential for G1/S transition. Has a role in S-phase checkpoint control induced by replication fork blocks after nucleotide deprivation a [...]
pss1 protein networkhttps://string-db.org/network/284812.O59838Heat shock protein homolog pss1; Required for normal growth at various temperatures.
inv1 protein networkhttps://string-db.org/network/284812.O59852Invertase; Belongs to the glycosyl hydrolase 32 family.
ssa2 protein networkhttps://string-db.org/network/284812.O59855Probable heat shock protein ssa2.
mrpl33 protein networkhttps://string-db.org/network/284812.O59856Probable 54S ribosomal protein L33, mitochondrial.
gpx1 protein networkhttps://string-db.org/network/284812.O59858Glutathione peroxidase-like peroxiredoxin gpx1; Glutathione peroxidase-like protein that protects cells during oxidative stress. Has peroxidase activity reducing hydrogen peroxide, alkyl and phos [...]
rps2402 protein networkhttps://string-db.org/network/284812.O5986540S ribosomal protein S24-B.
wbp1 protein networkhttps://string-db.org/network/284812.O59866Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit wbp1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3 [...]
pmr1 protein networkhttps://string-db.org/network/284812.O59868Calcium-transporting ATPase 1; Transports calcium and manganese ions into the cell. Regulates cell morphogenesis through control of manganese and calcium homeostasis.
ght4 protein networkhttps://string-db.org/network/284812.O59932High-affinity hexose transporter ght4.
fim1 protein networkhttps://string-db.org/network/284812.O59945Fimbrin; Binds to actin, and functionally associates with actin structures involved in the development and maintenance of cell polarity. Plays a role in cytokinesis. Plays important roles in mati [...]
clr4 protein networkhttps://string-db.org/network/284812.O60016Histone-lysine N-methyltransferase, H3 lysine-9 specific; Histone methyltransferase. Catalytic component of the rik1- associated E3 ubiquitin ligase complex that shows ubiquitin ligase activity a [...]
cwp1 protein networkhttps://string-db.org/network/284812.O60052Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl diphosphate to a cystei [...]
pof12 protein networkhttps://string-db.org/network/284812.O60053F-box protein pof12.
arp10 protein networkhttps://string-db.org/network/284812.O60054Actin-like protein arp10.
utp20 protein networkhttps://string-db.org/network/284812.O60055U3 small nucleolar RNA-associated protein 20; Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
SPBC56F2.05c protein networkhttps://string-db.org/network/284812.O60056Uncharacterized transcriptional regulatory protein C56F2.05c.
mug147 protein networkhttps://string-db.org/network/284812.O60057Meiotically up-regulated gene 147 protein; Has a role in meiosis.
SPBC56F2.07c protein networkhttps://string-db.org/network/284812.O60058ATPase family gene 2 protein; ATP-dependent chaperone which uses the energy provided by ATP hydrolysis to generate mechanical force to disassemble protein complexes. Plays an essential role in th [...]
puf1 protein networkhttps://string-db.org/network/284812.O60059Pumilio domain-containing protein C56F2.08c.
arg5 protein networkhttps://string-db.org/network/284812.O60060Carbamoyl-phosphate synthase arginine-specific small chain; Belongs to the CarA family.
alg5 protein networkhttps://string-db.org/network/284812.O60061Dolichyl-phosphate beta-glucosyltransferase.
met6 protein networkhttps://string-db.org/network/284812.O60062Homoserine O-acetyltransferase.
nam9 protein networkhttps://string-db.org/network/284812.O6006337S ribosomal protein S4-like, mitochondrial.
mpg2 protein networkhttps://string-db.org/network/284812.O60064Probable mannose-1-phosphate guanyltransferase; Involved in cell wall synthesis where it is required for glycosylation; Belongs to the transferase hexapeptide repeat family.
pex14 protein networkhttps://string-db.org/network/284812.O60065Peroxisomal membrane protein pex14; Component of the peroxisomal translocation machinery with pex13 and pex17; Belongs to the peroxin-14 family.
abh1 protein networkhttps://string-db.org/network/284812.O60066Alpha-ketoglutarate-dependent dioxygenase abh1; Putative dioxygenase that may repair alkylated DNA or RNA by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron (By s [...]
SPBC13G1.05 protein networkhttps://string-db.org/network/284812.O60067Endoplasmic reticulum membrane protein 65; May be involved in membrane protein folding.
isd11 protein networkhttps://string-db.org/network/284812.O60068Protein isd11; Required for mitochondrial iron-sulfur (Fe-S) protein biosynthesis; Belongs to the complex I LYR family.
swf1 protein networkhttps://string-db.org/network/284812.O60069Palmitoyltransferase swf1; Palmitoyltransferase that targets several endosomal SNAREs. Palmitoylates the SNAREs at cysteine residues close to the cytoplasmic end of their transmembrane domain. Ma [...]
ash2 protein networkhttps://string-db.org/network/284812.O60070Set1 complex component ash2; The Set1 complex specifically methylates 'Lys-4' of histone H3.
enp1 protein networkhttps://string-db.org/network/284812.O60071Uncharacterized protein C13G1.09; Belongs to the bystin family.
slh1 protein networkhttps://string-db.org/network/284812.O60072Putative helicase mug81; Has a role in meiosis.
ykt6 protein networkhttps://string-db.org/network/284812.O60073Synaptobrevin homolog ykt6.
did2 protein networkhttps://string-db.org/network/284812.O60074Vacuolar protein-sorting-associated protein 46; Class E VPS protein implicated in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal [...]
taf13 protein networkhttps://string-db.org/network/284812.O60076Transcription initiation factor TFIID subunit 13; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA elem [...]
arz1 protein networkhttps://string-db.org/network/284812.O60077Armadillo repeat-containing zfs1 target protein 1.
tyr1 protein networkhttps://string-db.org/network/284812.O60078Probable prephenate dehydrogenase [NADP(+)].
ubp12 protein networkhttps://string-db.org/network/284812.O60079Probable ubiquitin carboxyl-terminal hydrolase 12.
dbp9 protein networkhttps://string-db.org/network/284812.O60080ATP-dependent RNA helicase dbp9; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD [...]
trm732 protein networkhttps://string-db.org/network/284812.O60081Uncharacterized protein C1494.07; May be involved in the methylation of the 2'-O-ribose of nucleotides at position 32 of the tRNA anticodon loop of tRNA(Phe) and tRNA(Leu(UAA)) by SPAC4F10.03c.
SPCC1494.08c protein networkhttps://string-db.org/network/284812.O60082Uncharacterized protein C1494.08c; To yeast YBL086c.
tfb6 protein networkhttps://string-db.org/network/284812.O60083Uncharacterized protein C1494.09c.
tim44 protein networkhttps://string-db.org/network/284812.O60084Mitochondrial import inner membrane translocase subunit tim44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inn [...]
fma2 protein networkhttps://string-db.org/network/284812.O60085Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence [...]
ilv6 protein networkhttps://string-db.org/network/284812.O60086Probable acetolactate synthase small subunit; Stimulates activity of the acetolactate synthase catalytic subunit ilv1.
meu17 protein networkhttps://string-db.org/network/284812.O60087Probable glucoamylase.
dbl3 protein networkhttps://string-db.org/network/284812.O60090IMPACT family member C14C8.09c; Belongs to the IMPACT family.
mrpl24 protein networkhttps://string-db.org/network/284812.O6009154S ribosomal protein L24, mitochondrial.
ber1 protein networkhttps://string-db.org/network/284812.O60093SRR1-like protein.
pol5 protein networkhttps://string-db.org/network/284812.O60094rDNA transcriptional regulator pol5; Plays an important role in the regulation of rRNA transcription. Binds to rDNA promoter fragments. Belongs to the MYBBP1A family.
SPBC14C8.15 protein networkhttps://string-db.org/network/284812.O60095Probable lipase C14C8.15; Probable lipase; Belongs to the AB hydrolase superfamily. Lipase family.
bot1 protein networkhttps://string-db.org/network/284812.O6009637S ribosomal protein S35, mitochondrial; Required for mitochondrial protein synthesis. Has a role in mitochondrial integrity and cell respiration.
spt8 protein networkhttps://string-db.org/network/284812.O60097Transcription factor spt8; Functions as a component of the transcription regulatory histone acetylation (HAT) complex SAGA. SAGA is involved in RNA polymerase II-dependent transcriptional regulat [...]
trs65 protein networkhttps://string-db.org/network/284812.O60099Uncharacterized protein C14F5.02.
kap123 protein networkhttps://string-db.org/network/284812.O60100Probable importin subunit beta-4; Required for nuclear protein import, its predominant substrate seems to be ribosomal proteins. Binds to nucleoporins and the GTP-bound form of gsp1 (Ran) (By sim [...]
pgk1 protein networkhttps://string-db.org/network/284812.O60101Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
rli1 protein networkhttps://string-db.org/network/284812.O60102Translation initiation factor rli1; Component of the multifactor complex (MFC) involved in translation initiation. Required for the binding of MFC to the 40S ribosome. Required for the processing [...]
doa10 protein networkhttps://string-db.org/network/284812.O60103ERAD-associated E3 ubiquitin-protein ligase doa10; E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated E2 ligases, and transfers it to substrate [...]
med7 protein networkhttps://string-db.org/network/284812.O60104Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Me [...]
ade8 protein networkhttps://string-db.org/network/284812.O60105Adenylosuccinate lyase.
SPBC14F5.10c protein networkhttps://string-db.org/network/284812.O60106LON peptidase N-terminal domain and RING finger protein C14F5.10c.
snx41 protein networkhttps://string-db.org/network/284812.O60107Sorting nexin-41; May be required for cytoplasm to vacuole transport (Cvt) and pexophagy (By similarity). Has a role in meiosis.
cbh2 protein networkhttps://string-db.org/network/284812.O60108CENP-B homolog protein 2; Binds to the central core and core-associated repeat regions of centromeric heterochromatin.
pho8 protein networkhttps://string-db.org/network/284812.O60109Alkaline phosphatase; Belongs to the alkaline phosphatase family.
oca3 protein networkhttps://string-db.org/network/284812.O60110TPR repeat protein oca3; May be involved in cell cycle regulation.
SPBC15C4.02 protein networkhttps://string-db.org/network/284812.O60111ABC1 family protein MCP2 homolog; Involved in mitochondrial lipid homeostasis. Belongs to the protein kinase superfamily. ADCK protein kinase family.
mrs6 protein networkhttps://string-db.org/network/284812.O60112Uncharacterized Rab geranylgeranyltransferase C15C4.03.
SPBC15C4.04c protein networkhttps://string-db.org/network/284812.O60113Uncharacterized amino-acid permease C15C4.04c.
dhx29 protein networkhttps://string-db.org/network/284812.O60114Uncharacterized helicase C15C4.05.
rbk1 protein networkhttps://string-db.org/network/284812.O60116Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histi [...]
mrz1 protein networkhttps://string-db.org/network/284812.O60117Uncharacterized RING finger protein C16G5.03.
mrpl23 protein networkhttps://string-db.org/network/284812.O6011854S ribosomal protein L23, mitochondrial; Belongs to the universal ribosomal protein uL13 family.
scs2 protein networkhttps://string-db.org/network/284812.O60119Vesicle-associated membrane protein-associated protein C16G5.05c; Targets proteins containing a FFAT motif to endoplasmic reticulum membranes.
SPBC16G5.07c protein networkhttps://string-db.org/network/284812.O60121Uncharacterized protein C16G5.07c.
trp4 protein networkhttps://string-db.org/network/284812.O60122Anthranilate phosphoribosyltransferase; Belongs to the anthranilate phosphoribosyltransferase family.
kex1 protein networkhttps://string-db.org/network/284812.O60123Pheromone-processing carboxypeptidase kex1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Pro [...]
rrp42 protein networkhttps://string-db.org/network/284812.O60124Exosome complex component rrp42; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrad [...]
bag101 protein networkhttps://string-db.org/network/284812.O60125BAG family molecular chaperone regulator 1A; Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.
top3 protein networkhttps://string-db.org/network/284812.O60126DNA topoisomerase 3; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA dup [...]
ptf2 protein networkhttps://string-db.org/network/284812.O60127Pdp3-interacting factor 2; Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3K14 ace [...]
rps3 protein networkhttps://string-db.org/network/284812.O6012840S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
fkh2 protein networkhttps://string-db.org/network/284812.O60129Fork head protein homolog 2; Required for promoter sequence element PCB-driven, M-phase- specific transcription. Acts as a transcriptional activator with a role in the regulation of mitosis. Bind [...]
SPBC16G5.16 protein networkhttps://string-db.org/network/284812.O60130Putative transcriptional regulatory protein C16G5.16.
tea4 protein networkhttps://string-db.org/network/284812.O60132Tip elongation aberrant protein Tea4; Cell polarity factor essential for the bipolar localization and function of structures containing the cell-end marker tea1 during the normal cell cycle. Regu [...]
lcf1 protein networkhttps://string-db.org/network/284812.O60135Long-chain-fatty-acid--CoA ligase 1; Esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorpo [...]
swd2 protein networkhttps://string-db.org/network/284812.O60137Set1 complex component swd2; The Set1 complex specifically methylates 'Lys-4' of histone H3.
wbp4 protein networkhttps://string-db.org/network/284812.O60138Uncharacterized protein C18H10.07.
ubp4 protein networkhttps://string-db.org/network/284812.O60139Probable ubiquitin carboxyl-terminal hydrolase 4; Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Acts late in the proteolytic pathway in conjunc [...]
SPBC18H10.09 protein networkhttps://string-db.org/network/284812.O60140Uncharacterized protein C18H10.09.
saf4 protein networkhttps://string-db.org/network/284812.O60141Protein saf4; May be involved in mRNA splicing; Belongs to the CWC16 family.
ppr2 protein networkhttps://string-db.org/network/284812.O60142Pentatricopeptide repeat-containing protein 2, mitochondrial; Mitochondrial RNA-binding protein that acts as a general translation factor.
rpl701 protein networkhttps://string-db.org/network/284812.O6014360S ribosomal protein L7-C.
cdk11 protein networkhttps://string-db.org/network/284812.O60145Serine/threonine-protein kinase ppk23.
vhc1 protein networkhttps://string-db.org/network/284812.O60146Uncharacterized transporter C18H10.16.
mhr1 protein networkhttps://string-db.org/network/284812.O60147Uncharacterized protein C18H10.17c.
SPBC18H10.18c protein networkhttps://string-db.org/network/284812.O60148Uncharacterized membrane protein C18H10.18c.
vps38 protein networkhttps://string-db.org/network/284812.O60149Vacuolar protein sorting-associated protein 38; Involved in endosome-to-Golgi retrograde transport as part of the vps34 PI3-kinase complex II. Mediates the interaction between atg6 and the pik3-p [...]
any1 protein networkhttps://string-db.org/network/284812.O60150Uncharacterized protein C18H10.20c.
ubr1 protein networkhttps://string-db.org/network/284812.O60152E3 ubiquitin-protein ligase ubr1; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabil [...]
SPBC19C7.04c protein networkhttps://string-db.org/network/284812.O60153Uncharacterized protein C19C7.04c.
rcr1 protein networkhttps://string-db.org/network/284812.O60154Uncharacterized protein C19C7.05.
prs1 protein networkhttps://string-db.org/network/284812.O60155Putative proline--tRNA ligase C19C7.06; Belongs to the class-II aminoacyl-tRNA synthetase family.
sen34 protein networkhttps://string-db.org/network/284812.O60156Probable tRNA-splicing endonuclease subunit sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage o [...]
ppm2 protein networkhttps://string-db.org/network/284812.O60157tRNA wybutosine-synthesizing protein 4; Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modifie [...]
bqt4 protein networkhttps://string-db.org/network/284812.O60158Bouquet formation protein 4; Connects telomeres to the nuclear envelop (NE) during both vegetative growth and meiosis. This connection ensures clustering of telomeres to the spindle pole body (SP [...]
SPBC19C7.11 protein networkhttps://string-db.org/network/284812.O60159Putative anion/proton exchange transporter C19C7.11; Anion/proton exchange transporter involved in iron and copper cation homeostasis.
omh1 protein networkhttps://string-db.org/network/284812.O60160O-glycoside alpha-1,2-mannosyltransferase omh1; Mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins. Plays a major role in extending alpha-1,2-linked mannose in the [...]
utp4 protein networkhttps://string-db.org/network/284812.O60161U3 small nucleolar RNA-associated protein 4; Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a su [...]
sac11 protein networkhttps://string-db.org/network/284812.O60162Uncharacterized protein C19F5.03.
SPBC19F5.04 protein networkhttps://string-db.org/network/284812.O60163Probable aspartokinase; Belongs to the aspartokinase family.
ppp1 protein networkhttps://string-db.org/network/284812.O60164Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
spn7 protein networkhttps://string-db.org/network/284812.O60165Septin homolog spn7; Septin-like protein involved in the correct orientation of forespore membrane extension during sporulation. Binds phosphatidylinositol 4-phosphate.
nud3 protein networkhttps://string-db.org/network/284812.O60166Nuclear movement protein nudc; Required for nuclear movement. May interact between microtubules and nuclei and/or may be involved in the generation of force used to move nuclei during interphase [...]
yap18 protein networkhttps://string-db.org/network/284812.O60167ENTH domain-containing protein C19F8.03c.
lcl3 protein networkhttps://string-db.org/network/284812.O60168Probable endonuclease C19F8.04c.
meu22 protein networkhttps://string-db.org/network/284812.O60170Probable amino-acid permease meu22.
taf10 protein networkhttps://string-db.org/network/284812.O60171Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) [...]
SPBC21H7.03c protein networkhttps://string-db.org/network/284812.O60172Thiamine-repressible acid phosphatase SPBC21H7.03c; May dephosphorylate thiamine phosphates. Belongs to the histidine acid phosphatase family.
dbp7 protein networkhttps://string-db.org/network/284812.O60173ATP-dependent RNA helicase dbp7; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
sfc6 protein networkhttps://string-db.org/network/284812.O60174Transcription factor tau subunit sfc6; TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the i [...]
opi10 protein networkhttps://string-db.org/network/284812.O60175Protein OPI10 homolog.
cxr1 protein networkhttps://string-db.org/network/284812.O60176Uncharacterized RNA-binding protein C23E6.01c.
rrp2 protein networkhttps://string-db.org/network/284812.O60177Uncharacterized ATP-dependent helicase C23E6.02.
nta1 protein networkhttps://string-db.org/network/284812.O60178Protein N-terminal amidase; Deamidates N-terminal Asn and Gln. Component of a targeting complex in the N-end rule pathway (By similarity); Belongs to the carbon-nitrogen hydrolase superfamily.
utp10 protein networkhttps://string-db.org/network/284812.O60179U3 small nucleolar RNA-associated protein 10; Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a s [...]
arx1 protein networkhttps://string-db.org/network/284812.O60180Probable metalloprotease arx1; Probable metalloprotease involved in proper assembly of pre- ribosomal particles during the biogenesis of the 60S ribosomal subunit. Accompanies the pre-60S particl [...]
rib3 protein networkhttps://string-db.org/network/284812.O601813,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
rfc1 protein networkhttps://string-db.org/network/284812.O60182Replication factor C subunit 1; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. Subunit 1 is essenti [...]
rgp1 protein networkhttps://string-db.org/network/284812.O60183Protein sat1.
ssn6 protein networkhttps://string-db.org/network/284812.O60184General transcriptional corepressor ssn6; Acts as component of the ssn6-tup corepressor complexes, which are involved in the repression of many genes in a wide variety of physiological processes. [...]
mri1 protein networkhttps://string-db.org/network/284812.O60185Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/de [...]
rsm10 protein networkhttps://string-db.org/network/284812.O6018637S ribosomal protein S10, mitochondrial; Involved in mitochondrial genome encoded proteins translation. Involved in the binding of tRNA to the ribosomes (By similarity).
sid4 protein networkhttps://string-db.org/network/284812.O60187Septation initiation protein sid4; Required for activation of the spg1 GTPase signaling cascade which leads to the initiation of septation and the subsequent termination of mitosis. May act as a [...]
utp6 protein networkhttps://string-db.org/network/284812.O60188U3 small nucleolar RNA-associated protein 6; Component of the SSU processome, a pre-ribosomal particle required for the maturation of the 18S rRNA from the 35S pre-rRNA precursor.
sam1 protein networkhttps://string-db.org/network/284812.O60198S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S [...]
cdc45 protein networkhttps://string-db.org/network/284812.O74113Cell division control protein 45 homolog; Required for initiation of chromosomal DNA replication. May have a role in regulating the MCM proteins nda1 and nda4. Belongs to the CDC45 family.
cki3 protein networkhttps://string-db.org/network/284812.O74135Casein kinase I homolog 3; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.
rps2501 protein networkhttps://string-db.org/network/284812.O7417240S ribosomal protein S25-B; Belongs to the eukaryotic ribosomal protein eS25 family.
tef5 protein networkhttps://string-db.org/network/284812.O74173Elongation factor 1-beta; EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP; Belongs to the EF-1-beta/EF-1-delta family.
vma10 protein networkhttps://string-db.org/network/284812.O74174V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in euk [...]
rpl13 protein networkhttps://string-db.org/network/284812.O7417560S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.
osh41 protein networkhttps://string-db.org/network/284812.O74178Protein kes1; Plays a role in ergosterol synthesis.
pop3 protein networkhttps://string-db.org/network/284812.O74184Target of rapamycin complex subunit wat1; component of both TORC1 and TORC2, which regulate multiple cellular processes to control cell growth in response to environmental signals. Nutrient limit [...]
ani1 protein networkhttps://string-db.org/network/284812.O74191FK506-binding protein 39 kDa; PPIase that acts as a histone chaperone. Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail. [...]
dak2 protein networkhttps://string-db.org/network/284812.O74215Dihydroxyacetone kinase 2; Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.
win1 protein networkhttps://string-db.org/network/284812.O74304MAP kinase kinase kinase win1; Involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Activates the wis1 MAP kinase kinase by p [...]
rpl502 protein networkhttps://string-db.org/network/284812.O7430660S ribosomal protein L5-B; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger R [...]
gsf1 protein networkhttps://string-db.org/network/284812.O74308Uncharacterized transcriptional regulatory protein C15D4.02.
slm9 protein networkhttps://string-db.org/network/284812.O74309Histone transcription regulator slm9; Probably required for replication-independent chromatin assembly (By similarity). Required for transcriptional silencing in the outer repeat (otr) centromeri [...]
zng1 protein networkhttps://string-db.org/network/284812.O74310COBW domain-containing protein C15D4.05; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.
naa30 protein networkhttps://string-db.org/network/284812.O74311N-alpha-acetyltransferase 30; Catalytic component of the NatC N-terminal acetyltransferase.
atg9 protein networkhttps://string-db.org/network/284812.O74312Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore a [...]
SPBC15D4.08c protein networkhttps://string-db.org/network/284812.O74313Putative uncharacterized protein C15D4.08c.
met3 protein networkhttps://string-db.org/network/284812.O74314Probable cystathionine gamma-synthase; Catalyzes the formation of L-cystathionine from O-succinyl-L- homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, c [...]
amo1 protein networkhttps://string-db.org/network/284812.O74315Nucleoporin-like protein amo1; Involved in the cell polarity process where it is required for the correct termination of microtubule growth at the cell ends during interphase.
taf51 protein networkhttps://string-db.org/network/284812.O74319Transcription initiation factor TFIID subunit taf73; TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcriptio [...]
rps1202 protein networkhttps://string-db.org/network/284812.O7432240S ribosomal protein S12-B.
sec11 protein networkhttps://string-db.org/network/284812.O74323Signal peptidase complex catalytic subunit sec11; Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to th [...]
htr11 protein networkhttps://string-db.org/network/284812.O74325PDZ domain-containing protein C1685.05.
cid11 protein networkhttps://string-db.org/network/284812.O74326Poly(A) RNA polymerase cid11.
avt5 protein networkhttps://string-db.org/network/284812.O74327Vacuolar amino acid transporter 5; Vacuolar amino acid transporter involved in the vacuolar uptake of histidine, glutamate, tyrosine, arginine, lysine, and serine. Required for sporulation; Belon [...]
rps29 protein networkhttps://string-db.org/network/284812.O7432940S ribosomal protein S29; Belongs to the universal ribosomal protein uS14 family.
rps27 protein networkhttps://string-db.org/network/284812.O7433040S ribosomal protein S27.
rlp1 protein networkhttps://string-db.org/network/284812.O74331DNA repair protein rlp1; Required for normal levels of meiotic recombination. Acts in the recombinational pathway of double-strand break (DSB) repair together with rhp51, rhp55 and rad22. Require [...]
fhn1 protein networkhttps://string-db.org/network/284812.O74333Non-classical export protein 2 homolog; Involved in membrane organization and might act as a sensor of sphingolipids that regulates plasma membrane function. Involved in a novel pathway of export [...]
rga5 protein networkhttps://string-db.org/network/284812.O74335Rho-GTPase-activating protein 5; GTPase-activating protein for Rho1. Has a role in the negative regulation of (1-3)beta-D-glucan synthase activity and cell integrity.
blt1 protein networkhttps://string-db.org/network/284812.O74338Mitosis inducer protein blt1; At the onset of mitosis, forms a medial ring structure before the arrangement of the medial actin ring. Essential for the central positioning of the division septum [...]
tam41 protein networkhttps://string-db.org/network/284812.O74339Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosyn [...]
sof1 protein networkhttps://string-db.org/network/284812.O74340Protein sof1; Required for ribosomal RNA processing.
cct3 protein networkhttps://string-db.org/network/284812.O74341T-complex protein 1 subunit gamma; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
SPBC1A4.11c protein networkhttps://string-db.org/network/284812.O74342Uncharacterized protein C1A4.11c.
pus7 protein networkhttps://string-db.org/network/284812.O74343Multisubstrate pseudouridine synthase 7; Catalyzes pseudouridylation at position 35 in U2 snRNA stem- loop II region which induces particular conformation of the mRNA-U2 snRNA duplex and places t [...]
ucp3 protein networkhttps://string-db.org/network/284812.O74345UBA domain-containing protein 3.
map4 protein networkhttps://string-db.org/network/284812.O74346P cell-type agglutination protein map4; P cell-type specific protein which involved in agglutination during conjugation.
rkr1 protein networkhttps://string-db.org/network/284812.O74349E3 ubiquitin-protein ligase listerin; E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extractio [...]
bdc1 protein networkhttps://string-db.org/network/284812.O74350Bromodomain-containing protein 1; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosom [...]
nfs1 protein networkhttps://string-db.org/network/284812.O74351Probable cysteine desulfurase, mitochondrial; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters. Plays [...]
hob1 protein networkhttps://string-db.org/network/284812.O74352Protein hob1; Has a role in DNA damage signaling as a part of stress response processes.
dnt1 protein networkhttps://string-db.org/network/284812.O74354Nucleolar protein dnt1; Negatively regulates the septation initiation network (SIN) pathway, independently of the cdc14 phosphatase clp1. May also have a role in silencing rDNA transcription. Req [...]
mrh5 protein networkhttps://string-db.org/network/284812.O74356Putative ATP-dependent RNA helicase C25D12.06; Belongs to the DEAD box helicase family.
apc13 protein networkhttps://string-db.org/network/284812.O74358Anaphase-promoting complex subunit 13; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through [...]
SPBC28E12.02 protein networkhttps://string-db.org/network/284812.O74359Meiotically up-regulated gene 60 protein; Has a role in meiosis.
rga4 protein networkhttps://string-db.org/network/284812.O74360Probable Rho-type GTPase-activating protein 4; GTPase-activating protein for Rho-type proteins.
cbp7 protein networkhttps://string-db.org/network/284812.O74361Uncharacterized protein C28E12.04.
esf2 protein networkhttps://string-db.org/network/284812.O74362Pre-rRNA-processing protein esf2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By [...]
sqs1 protein networkhttps://string-db.org/network/284812.O74363G-patch and R3H domain-containing protein C30B4.02c.
ldb1 protein networkhttps://string-db.org/network/284812.O74364Adhesion defective protein 1; Probable transcriptional regulator involved in cell adhesion. Belongs to the adn1/SEU family.
sol1 protein networkhttps://string-db.org/network/284812.O74365SWI/SNF chromatin-remodeling complex subunit sol1; Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expre [...]
tfb4 protein networkhttps://string-db.org/network/284812.O74366General transcription and DNA repair factor IIH subunit tfb4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription [...]
mmm1 protein networkhttps://string-db.org/network/284812.O74368Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of [...]
css1 protein networkhttps://string-db.org/network/284812.O74369Inositol phosphosphingolipids phospholipase C; Inositol phosphosphingolipids phospholipase essential for the coordination of cell wall formation. Responsible for the hydrolysis of the phosphosphi [...]
cwf12 protein networkhttps://string-db.org/network/284812.O74370Pre-mRNA-splicing factor cwf12; Involved in mRNA splicing and cell cycle control; Belongs to the ISY1 family.
SPBC32F12.07c protein networkhttps://string-db.org/network/284812.O74371Uncharacterized RING finger protein C32F12.07c.
duo1 protein networkhttps://string-db.org/network/284812.O74372DASH complex subunit duo1; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates [...]
pgm1 protein networkhttps://string-db.org/network/284812.O74374Phosphoglucomutase; Catalyzes the reversible interconversion of glucose 1- phosphate and glucose 6-phosphate. Key enzyme in hexose metabolism. The reverse reaction is an essential step for biosyn [...]
SPBC32F12.12c protein networkhttps://string-db.org/network/284812.O74375Golgi apparatus membrane protein tvp18; Golgi membrane protein involved in vesicular trafficking. Belongs to the TVP18 family.
sul1 protein networkhttps://string-db.org/network/284812.O74377Probable sulfate permease C3H7.02; High affinity uptake of sulfate into the cell; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
kgd1 protein networkhttps://string-db.org/network/284812.O743782-oxoglutarate dehydrogenase, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of [...]
SPBC3H7.04 protein networkhttps://string-db.org/network/284812.O74379Putative 37S ribosomal protein S26B, mitochondrial.
SPBC3H7.05c protein networkhttps://string-db.org/network/284812.O74380Uncharacterized membrane protein C3H7.05c.
pof9 protein networkhttps://string-db.org/network/284812.O74381F-box protein pof9.
ser2 protein networkhttps://string-db.org/network/284812.O74382Probable phosphoserine phosphatase; Belongs to the HAD-like hydrolase superfamily. SerB family.
erf2 protein networkhttps://string-db.org/network/284812.O74384Palmitoyltransferase erf2; The erf2-erf4 complex is a palmitoyltransferase specific for Ras proteins (By similarity). Has a role in sporulation; Belongs to the DHHC palmitoyltransferase family. E [...]
elp6 protein networkhttps://string-db.org/network/284812.O74385Elongator complex protein 6 homolog; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved [...]
trm141 protein networkhttps://string-db.org/network/284812.O74386Uncharacterized methyltransferase C3H7.11; Probable methyltransferase; Belongs to the methyltransferase superfamily. METL family.
rav2 protein networkhttps://string-db.org/network/284812.O74387Regulator of V-ATPase in vacuolar membrane protein 2; Component of the RAVE complex which is required for stable assembly of the vacuolar ATPase complex V-ATPase.
far10 protein networkhttps://string-db.org/network/284812.O74388Uncharacterized protein C3H7.13.
rpl2502 protein networkhttps://string-db.org/network/284812.O7439160S ribosomal protein L25-B; This protein binds to a specific region on the 26S rRNA. Belongs to the universal ribosomal protein uL23 family.
mak5 protein networkhttps://string-db.org/network/284812.O74393ATP-dependent RNA helicase mak5; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD [...]
mrpl39 protein networkhttps://string-db.org/network/284812.O7439454S ribosomal protein L39, mitochondrial.
str1 protein networkhttps://string-db.org/network/284812.O74395Siderophore iron transporter 1; Involved in the transport of siderophore iron and so has a role in iron homeostasis; Belongs to the major facilitator superfamily.
vps901 protein networkhttps://string-db.org/network/284812.O74396Vacuolar protein sorting-associated protein 9a; Required for vacuolar protein sorting; may be required for the consumption of transport vesicles containing vacuolar protein precursors.
asn2 protein networkhttps://string-db.org/network/284812.O74397Asparagine synthetase domain-containing protein C4F6.11c.
pxl1 protein networkhttps://string-db.org/network/284812.O74398LIM domain-containing protein C4F6.12.
erb1 protein networkhttps://string-db.org/network/284812.O74399Ribosome biogenesis protein erb1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
nop4 protein networkhttps://string-db.org/network/284812.O74400Uncharacterized RNA-binding protein C4F6.14.
ero11 protein networkhttps://string-db.org/network/284812.O74401ERO1-like protein 1; Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly pdi1 isomerase through a direct disulfide [...]
hsp78 protein networkhttps://string-db.org/network/284812.O74402Heat shock protein 78, mitochondrial; Required, in concert with mitochondrial Hsp70, for the dissociation, resolubilization and refolding of aggregates of damaged proteins in the mitochondrial ma [...]
set11 protein networkhttps://string-db.org/network/284812.O74405Ribosomal lysine N-methyltransferase set11; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that trimethylates 60S ribosomal protein L12 (rpl1201 and rpl1202) at 'Lys-4' and [...]
drs1 protein networkhttps://string-db.org/network/284812.O74407Aspartate--tRNA ligase, cytoplasmic.
uro1 protein networkhttps://string-db.org/network/284812.O74409Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.
meu10 protein networkhttps://string-db.org/network/284812.O74411Meiotic expression up-regulated protein 10; Required for the formation of the mature spore wall, where it is needed to ensure correct localization of 1,3-beta-glucan.
cbf12 protein networkhttps://string-db.org/network/284812.O74412Transcription factor cbf12; Transcription factor which function may be to trigger the increase of adhesion at stationary phase, possibly by counteracting or replacing cbf11 at the respective prom [...]
aro2 protein networkhttps://string-db.org/network/284812.O74413Chorismate synthase; Belongs to the chorismate synthase family.
cab5 protein networkhttps://string-db.org/network/284812.O74414Uncharacterized protein C14G10.01.
urb1 protein networkhttps://string-db.org/network/284812.O74415Uncharacterized protein C14G10.02.
ump1 protein networkhttps://string-db.org/network/284812.O74416Probable proteasome maturation factor ump1; Short-lived chaperone present in the precursor form of the 20S proteasome and absent in the mature complex. Required for the correct assembly and enzym [...]
eap1 protein networkhttps://string-db.org/network/284812.O74417Uncharacterized protein C14G10.04.
snp27 protein networkhttps://string-db.org/network/284812.O74418U4/U6.U5 tri-snRNP-associated protein 3-like protein C162.01c; May play a role in mRNA splicing.
SPCC162.02c protein networkhttps://string-db.org/network/284812.O74419Uncharacterized protein C162.02c; Belongs to the ATP-dependent AMP-binding enzyme family.
wtf13 protein networkhttps://string-db.org/network/284812.O74420Uncharacterized protein wtf13.
coq3 protein networkhttps://string-db.org/network/284812.O74421Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
vps60 protein networkhttps://string-db.org/network/284812.O74422Uncharacterized protein C162.06c; Belongs to the SNF7 family.
ent1 protein networkhttps://string-db.org/network/284812.O74423Epsin-1; Binds to membranes enriched in phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization [...]
nup211 protein networkhttps://string-db.org/network/284812.O74424Nucleoporin nup211; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural component [...]
ppk33 protein networkhttps://string-db.org/network/284812.O74426Serine/threonine-protein kinase ppk33; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
urk1 protein networkhttps://string-db.org/network/284812.O74427Uridine kinase; Catalyzes the conversion of uridine into UMP and cytidine into CMP in the pyrimidine salvage pathway.
tco89 protein networkhttps://string-db.org/network/284812.O74428Target of rapamycin complex 1 subunit tco89; Component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. Tor2 is essential for gro [...]
asp1 protein networkhttps://string-db.org/network/284812.O74429Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing in [...]
SPCC1672.09 protein networkhttps://string-db.org/network/284812.O74430Probable lipase C1672.09; Probable lipase; Belongs to the AB hydrolase superfamily. Lipase family.
SPCC1672.11c protein networkhttps://string-db.org/network/284812.O74431Probable cation-transporting ATPase C1672.11c; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
get4 protein networkhttps://string-db.org/network/284812.O74432Golgi to ER traffic protein 4; May play a role in insertion of tail-anchored proteins into the endoplasmic reticulum membrane; Belongs to the GET4 family.
qcr9 protein networkhttps://string-db.org/network/284812.O74433Cytochrome b-c1 complex subunit 9; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which dr [...]
cdc31 protein networkhttps://string-db.org/network/284812.O74435Cell division control protein 31; Required for the proper coordination between exit from mitosis and the initiation of septation. Has a role in bipolar spindle formation during spindle pole body [...]
srp68 protein networkhttps://string-db.org/network/284812.O74436Signal recognition particle subunit srp68; Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is r [...]
mpf2 protein networkhttps://string-db.org/network/284812.O74438Meiotic coiled-coil protein 2.
ggc1 protein networkhttps://string-db.org/network/284812.O74439Uncharacterized mitochondrial carrier C1682.09c.
rpn8 protein networkhttps://string-db.org/network/284812.O7444026S proteasome regulatory subunit rpn8; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
ctl1 protein networkhttps://string-db.org/network/284812.O74441Choline transporter-like protein ctl1; Required for the normal organization of the preautophagosomal structure (PAS) and for the correct subcellular location of atg9. Belongs to the CTL (choline [...]
ubp16 protein networkhttps://string-db.org/network/284812.O74442Probable ubiquitin carboxyl-terminal hydrolase 16.
laf2 protein networkhttps://string-db.org/network/284812.O74443SWIRM domain-containing protein laf2; Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones [...]
mug122 protein networkhttps://string-db.org/network/284812.O74444Meiotically up-regulated gene 122 protein; Has a role in meiosis; Belongs to the sorting nexin family.
rpt4 protein networkhttps://string-db.org/network/284812.O74445Probable 26S proteasome subunit rpt4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and subs [...]
sif2 protein networkhttps://string-db.org/network/284812.O74446Sad1-interacting factor 2; Required for sporulation where it is believed to have a role in meiotic nuclear division.
SPCC16C4.02c protein networkhttps://string-db.org/network/284812.O74447Uncharacterized protein C16C4.02c.
pin1 protein networkhttps://string-db.org/network/284812.O74448Peptidyl-prolyl cis-trans isomerase pin1; Has a role in the G1/S stage transition of mitosis where it is involved in the dephosphorylation of cdc25 and wee1.
SPCC16C4.04 protein networkhttps://string-db.org/network/284812.O74449Uncharacterized protein C16C4.04.
pop23 protein networkhttps://string-db.org/network/284812.O74450Ribonucleases P/MRP protein subunit pop3; Required for processing of 5.8S rRNA (short form) at site A3 and for 5'- and 3'-processing of pre-tRNA.
pus3 protein networkhttps://string-db.org/network/284812.O74451Putative tRNA pseudouridine synthase C16C4.06c; Belongs to the tRNA pseudouridine synthase TruA family.
scw1 protein networkhttps://string-db.org/network/284812.O74452Cell wall integrity protein scw1; Acts as a negative regulator of cell wall and septum deposition.
skb15 protein networkhttps://string-db.org/network/284812.O74453Shk1 kinase-binding protein 15; Negatively regulates pak1/shk1 kinase activity leading to proper execution of cytoskeletal remodeling and cytokinetic functions.
sts5 protein networkhttps://string-db.org/network/284812.O74454Protein sts5; Required for the maintenance of cell shape during interphase. Required for localization of cortical actin to the growing tips before mitosis.
pgl1 protein networkhttps://string-db.org/network/284812.O74455Probable 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
pef1 protein networkhttps://string-db.org/network/284812.O74456Serine/threonine-protein kinase pef1.
naa20 protein networkhttps://string-db.org/network/284812.O74457N-terminal acetyltransferase B complex catalytic subunit naa20; Catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues o [...]
sfc4 protein networkhttps://string-db.org/network/284812.O74458Transcription factor tau subunit sfc4; TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the i [...]
cbc3 protein networkhttps://string-db.org/network/284812.O74460Uncharacterized protein C16C4.16c.
mug123 protein networkhttps://string-db.org/network/284812.O74461Meiotically up-regulated gene 123 protein; Involved in sporulation and has a role in meiosis.
taf6 protein networkhttps://string-db.org/network/284812.O74462Transcription initiation factor TFIID subunit 6; TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcription; B [...]
SPCC1739.01 protein networkhttps://string-db.org/network/284812.O74463Uncharacterized protein C1739.01.
mrpl22 protein networkhttps://string-db.org/network/284812.O7446454S ribosomal protein L22, mitochondrial.
hrr1 protein networkhttps://string-db.org/network/284812.O74465Helicase required for RNAi-mediated heterochromatin assembly 1; Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation and accurate chromosome segregat [...]
dms1 protein networkhttps://string-db.org/network/284812.O74466Uncharacterized protein C1739.04c.
set5 protein networkhttps://string-db.org/network/284812.O74467SET domain-containing protein 5; Belongs to the class V-like SAM-binding methyltransferase superfamily.
met1 protein networkhttps://string-db.org/network/284812.O74468Probable uroporphyrinogen-III C-methyltransferase; Siroheme synthase involved in methionine biosynthesis. Belongs to the precorrin methyltransferase family.
cti1 protein networkhttps://string-db.org/network/284812.O74469Exosome complex protein C1739.07; Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sit [...]
SPCC1739.08c protein networkhttps://string-db.org/network/284812.O74470Uncharacterized oxidoreductase C1739.08c.
cox13 protein networkhttps://string-db.org/network/284812.O74471Cytochrome c oxidase subunit 13, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The re [...]
mug33 protein networkhttps://string-db.org/network/284812.O74472Meiotically up-regulated gene 33 protein; Has a role in meiosis.
cdc11 protein networkhttps://string-db.org/network/284812.O74473Septation initiation network scaffold protein cdc11; Essential for the onset of septum formation. Involved in the organization of astral microtubules during mitosis. Acts as a bridge between sid4 [...]
wtf21 protein networkhttps://string-db.org/network/284812.O74474Uncharacterized protein wtf21.
bgs4 protein networkhttps://string-db.org/network/284812.O744751,3-beta-glucan synthase component bgs4; Belongs to the glycosyltransferase 48 family.
sal3 protein networkhttps://string-db.org/network/284812.O74476Importin subunit beta-3; Involved in the nuclear import of cdc25 and mcs1. Belongs to the importin beta family. Importin beta-3 subfamily.
pca1 protein networkhttps://string-db.org/network/284812.O74477Metacaspase-1; Involved in cell death (apoptosis).
pgm2 protein networkhttps://string-db.org/network/284812.O74478Probable phosphoribomutase; Converts ribose 1-phosphate to ribose 5-phosphate. Involved in ribose salvage via the pentose phosphate pathway. Belongs to the phosphohexose mutase family.
atp5 protein networkhttps://string-db.org/network/284812.O74479ATP synthase subunit 5, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
SPCC1840.07c protein networkhttps://string-db.org/network/284812.O74480Uncharacterized protein C1840.07c.
pdi5 protein networkhttps://string-db.org/network/284812.O74481Uncharacterized protein C1840.08c.
coq11 protein networkhttps://string-db.org/network/284812.O74482Uncharacterized protein C1840.09.
lsm8 protein networkhttps://string-db.org/network/284812.O74483U6 snRNA-associated Sm-like protein LSm8; Probable component of the spliceosome; Belongs to the snRNP Sm proteins family.
mpg1 protein networkhttps://string-db.org/network/284812.O74484Mannose-1-phosphate guanyltransferase; Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint. Required for the co [...]
cue3 protein networkhttps://string-db.org/network/284812.O74485CUE domain-containing protein 3.
wtf19 protein networkhttps://string-db.org/network/284812.O74486Uncharacterized protein wtf19.
wtf20 protein networkhttps://string-db.org/network/284812.O74487Uncharacterized protein wtf20.
zta1 protein networkhttps://string-db.org/network/284812.O74489Probable quinone oxidoreductase; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
ist1 protein networkhttps://string-db.org/network/284812.O74490Vacuolar protein sorting-associated protein ist1; Involved in a late step in sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. The lumenal s [...]
SPCC285.04 protein networkhttps://string-db.org/network/284812.O74492Probable 5-hydroxyisourate hydrolase; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyi [...]
SPCC285.05 protein networkhttps://string-db.org/network/284812.O74493Probable purine nucleoside permease C285.05; Probable nucleoside permease that transports adenosine and guanosine; Belongs to the NUP family.
wtf18 protein networkhttps://string-db.org/network/284812.O74495Uncharacterized protein wtf18.
ret2 protein networkhttps://string-db.org/network/284812.O74496Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynt [...]
ear1 protein networkhttps://string-db.org/network/284812.O74497SPRY domain-containing protein C285.10c.
dsc5 protein networkhttps://string-db.org/network/284812.O74498UBX domain-containing protein 10; Involved in protein degradation through the ubiquitin/proteasome pathway.
lsm7 protein networkhttps://string-db.org/network/284812.O74499U6 snRNA-associated Sm-like protein LSm7; Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. Probable component of the spliceoso [...]
nup60 protein networkhttps://string-db.org/network/284812.O74500Nucleoporin nup60; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components [...]
trs130 protein networkhttps://string-db.org/network/284812.O74501Uncharacterized protein CC285.14; Belongs to the TMEM1 family.
msh6 protein networkhttps://string-db.org/network/284812.O74502DNA mismatch repair protein msh6; Involved in post-replicative DNA-mismatch repair. Has a role towards base-base mispairs and insertion-deletion loops.
spp27 protein networkhttps://string-db.org/network/284812.O74503Upstream activation factor subunit spp27; Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable p [...]
duc1 protein networkhttps://string-db.org/network/284812.O74504UPF0590 protein C594.01; Belongs to the UPF0590 family.
SPCC594.02c protein networkhttps://string-db.org/network/284812.O74505Uncharacterized protein C594.02c.
spf1 protein networkhttps://string-db.org/network/284812.O74508Set1 complex component spp1; The Set1 complex specifically methylates 'Lys-4' of histone H3.
vsl1 protein networkhttps://string-db.org/network/284812.O74509Vacuolar morphogenesis protein 7 homolog; Essential for proper morphogenesis of the vacuole. May exist as structural reinforcement on the surface of the vacuolar membrane and be required for main [...]
bqt3 protein networkhttps://string-db.org/network/284812.O74510Bouquet formation protein 3; Connects telomeres to the nuclear envelop (NE) during both vegetative growth and meiosis. This connection ensures clustering of telomeres to the spindle pole body (SP [...]
ekc1 protein networkhttps://string-db.org/network/284812.O74511Extragenic suppressor of kinetochore protein 1; Has a role in chromosome segregation. May provide a dynamic connection between kinetochore microtubules and kinetochore chromatin. Belongs to the S [...]
wtf14 protein networkhttps://string-db.org/network/284812.O74512Uncharacterized protein wtf14.
cia1 protein networkhttps://string-db.org/network/284812.O74515Histone chaperone cia1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
trm44 protein networkhttps://string-db.org/network/284812.O74516tRNA (uracil-O(2)-)-methyltransferase; Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
saf1 protein networkhttps://string-db.org/network/284812.O74517Protein saf1.
cid12 protein networkhttps://string-db.org/network/284812.O74518Poly(A) RNA polymerase cid12; Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation and accurate chromosome segregation. A member of the RNA-directed [...]
naa50 protein networkhttps://string-db.org/network/284812.O74519Uncharacterized N-acetyltransferase C663.13c.
trp663 protein networkhttps://string-db.org/network/284812.O74520Uncharacterized membrane protein C663.14c.
SPCC663.15c protein networkhttps://string-db.org/network/284812.O74521Uncharacterized protein C663.15c.
adn3 protein networkhttps://string-db.org/network/284812.O74522Adhesion defective protein 3; Probable transcriptional regulator involved in cell adhesion. Belongs to the FLO8 family.
inh1 protein networkhttps://string-db.org/network/284812.O74523Putative ATPase inhibitor, mitochondrial; Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.
put1 protein networkhttps://string-db.org/network/284812.O74524Probable proline dehydrogenase, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate. Belongs to the proline oxidase family.
SPCC70.04c protein networkhttps://string-db.org/network/284812.O74525Uncharacterized membrane protein C70.04c.
nnk1 protein networkhttps://string-db.org/network/284812.O74526Probable serine/threonine-protein kinase C70.05c.
SPCC70.08c protein networkhttps://string-db.org/network/284812.O74529Uncharacterized methyltransferase C70.08c; Probable methyltransferase; Belongs to the methyltransferase superfamily.
pof7 protein networkhttps://string-db.org/network/284812.O74531F-box protein pof7.
qcr7 protein networkhttps://string-db.org/network/284812.O74533Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which dr [...]
sly1 protein networkhttps://string-db.org/network/284812.O74534Protein sly1.
ppn1 protein networkhttps://string-db.org/network/284812.O74535Cleavage and polyadenylation factor complex subunit C74.02c; RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation- dependent p [...]
ssp2 protein networkhttps://string-db.org/network/284812.O74536SNF1-like protein kinase ssp2; Serine/threonine protein kinase essential for release from glucose repression via the phosphorylation of scr1 upon glucose deprivation. Catalytic subunit of the AMP [...]
SPCC74.04 protein networkhttps://string-db.org/network/284812.O74537Uncharacterized amino-acid permease C74.04.
rpl2702 protein networkhttps://string-db.org/network/284812.O7453860S ribosomal protein L27-B.
mak3 protein networkhttps://string-db.org/network/284812.O74539Peroxide stress-activated histidine kinase mak3; Involved in the control of the SAPK-dependent transcriptional response to peroxide stress. Regulates sty1 activity.
fmd3 protein networkhttps://string-db.org/network/284812.O74540Putative S-(hydroxymethyl)glutathione dehydrogenase 2.
SPCC777.02 protein networkhttps://string-db.org/network/284812.O74541Uncharacterized transcriptional regulatory protein C777.02.
SPCC777.03c protein networkhttps://string-db.org/network/284812.O74542Uncharacterized aminotransferase C777.03c; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
dip5 protein networkhttps://string-db.org/network/284812.O74543Uncharacterized amino-acid permease C777.04.
gtr2 protein networkhttps://string-db.org/network/284812.O74544GTP-binding protein gtr2; GTPase. Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome (By similarity).
SPCC777.06c protein networkhttps://string-db.org/network/284812.O74545Putative hydrolase C777.06c.
omh3 protein networkhttps://string-db.org/network/284812.O74546O-glycoside alpha-1,2-mannosyltransferase homolog 3; Probable mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins; Belongs to the glycosyltransferase 15 family.
bit61 protein networkhttps://string-db.org/network/284812.O74547Target of rapamycin complex 2 subunit bit61; Component of TORC2, which regulates multiple cellular processes to control cell growth in response to environmental signals. TORC2 is required for cel [...]
arg1 protein networkhttps://string-db.org/network/284812.O74548Probable acetylornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
ubc12 protein networkhttps://string-db.org/network/284812.O74549NEDD8-conjugating enzyme ubc12; Accepts the ubiquitin-like protein NEDD8/RUB1 from the UBA3- ULA1 E1 complex and catalyzes its covalent attachment to other proteins; Belongs to the ubiquitin-conj [...]
gta3 protein networkhttps://string-db.org/network/284812.O74550Uncharacterized protein C777.11.
SPCC777.12c protein networkhttps://string-db.org/network/284812.O74551Uncharacterized protein C777.12c.
vps35 protein networkhttps://string-db.org/network/284812.O74552Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. Required for the endosome-to-Golgi retrieval of the vacuolar protein sorting receptor vps10. Required to [...]
dus4 protein networkhttps://string-db.org/network/284812.O74553tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
bpb1 protein networkhttps://string-db.org/network/284812.O74555Branchpoint-bridging protein; Necessary for the splicing of pre-mRNA. The BPB1(SF1)-u2af59- u2af23 complex has a role in the recognition of the branch site (5'- UACUAAC-3'), the pyrimidine tract [...]
dcw1 protein networkhttps://string-db.org/network/284812.O74556Putative mannan endo-1,6-alpha-mannosidase C970.02.
cbr1 protein networkhttps://string-db.org/network/284812.O74557NADH-cytochrome b5 reductase 1; Electron donor reductase for cytochrome b5. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several ster [...]
mob2 protein networkhttps://string-db.org/network/284812.O74558Maintenance of ploidy protein mob2; Required for coordinating polarized cell growth during interphase with the onset of mitosis; Belongs to the MOB1/phocein family.
erv29 protein networkhttps://string-db.org/network/284812.O74559Surfeit locus protein 4 homolog; Belongs to the SURF4 family.
raf2 protein networkhttps://string-db.org/network/284812.O74560Rik1-associated factor 2; Component of the rik1-associated E3 ubiquitin ligase complex that shows ubiquitin ligase activity and is required for histone H3K9 methylation. H3K9me represents a speci [...]
kcs1 protein networkhttps://string-db.org/network/284812.O74561Uncharacterized inositol polyphosphate kinase C970.08.
sec8 protein networkhttps://string-db.org/network/284812.O74562Exocyst complex component sec8; Component of the exocyst complex involved in the delivery of secretory vesicles to the plasma membrane. Also required for polarized cell growth and division septum [...]
brl2 protein networkhttps://string-db.org/network/284812.O74563E3 ubiquitin-protein ligase brl2; E3 ubiquitin-protein ligase which belongs to the histone H2B ubiquitin ligase complex (HULC) which mediates monoubiquitination of histone H2B to form H2BK123ub1. [...]
wtf9 protein networkhttps://string-db.org/network/284812.O74564Uncharacterized protein wtf9.
pch1 protein networkhttps://string-db.org/network/284812.O74627Cyclin pch1; Essential for progression through the whole cell cycle. Belongs to the cyclin family. Cyclin C subfamily.
SPCC162.03 protein networkhttps://string-db.org/network/284812.O74628Uncharacterized oxidoreductase C162.03.
tel1 protein networkhttps://string-db.org/network/284812.O74630Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA [...]
rpb9 protein networkhttps://string-db.org/network/284812.O74635DNA-directed RNA polymerase II subunit RPB9; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
iah1 protein networkhttps://string-db.org/network/284812.O74648Isoamyl acetate-hydrolyzing esterase.
pob1 protein networkhttps://string-db.org/network/284812.O74653Protein pob1; Has a role in cell elongation and separation.
snu13 protein networkhttps://string-db.org/network/284812.O7469013 kDa ribonucleoprotein-associated protein; Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for spli [...]
sup35 protein networkhttps://string-db.org/network/284812.O74718Eukaryotic peptide chain release factor GTP-binding subunit; Involved in translation termination. Stimulates the activity of ERF1. Binds guanine nucleotides; Belongs to the TRAFAC class translati [...]
cyp3 protein networkhttps://string-db.org/network/284812.O74729Peptidyl-prolyl cis-trans isomerase cyp3; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
dus2 protein networkhttps://string-db.org/network/284812.O74731tRNA-dihydrouridine(20) synthase [NAD(P)+]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
erg27 protein networkhttps://string-db.org/network/284812.O747323-keto-steroid reductase; Responsible for the reduction of the keto group on the C-3 of sterols.
cft1 protein networkhttps://string-db.org/network/284812.O74733Protein cft1; RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation- dependent pre-mRNA 3'-end formation and cooperates with cl [...]
rrf1 protein networkhttps://string-db.org/network/284812.O74734Putative ribosomal recycling factor, mitochondrial; Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria; Belongs to the RRF family.
atx1 protein networkhttps://string-db.org/network/284812.O74735Metal homeostasis factor atx1; Shuttles copper to the transport ATPase ccc2. Protects against oxygen toxicity (By similarity); Belongs to the ATX1 family.
png2 protein networkhttps://string-db.org/network/284812.O74736Chromatin modification-related protein png2; Component of the clr6 histone deacetylase complex I' responsible for the deacetylation of lysine residues on the N-terminal part of the core histones [...]
rid1 protein networkhttps://string-db.org/network/284812.O74737GTPase-binding protein rid1.
set10 protein networkhttps://string-db.org/network/284812.O74738Ribosomal lysine N-methyltransferase set10; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates ribosomal protein L23 (rpl23a and rpl23b); Belongs to the class V [...]
ngl1 protein networkhttps://string-db.org/network/284812.O74739Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degrad [...]
cft2 protein networkhttps://string-db.org/network/284812.O74740Cleavage factor two protein 2; RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation- dependent pre-mRNA 3'-end formation and c [...]
SPBC1709.16c protein networkhttps://string-db.org/network/284812.O747414,5-DOPA dioxygenase extradiol-like protein; May be involved in the metabolism of aromatic compounds.
met7 protein networkhttps://string-db.org/network/284812.O74742Probable folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these [...]
tif452 protein networkhttps://string-db.org/network/284812.O74743Eukaryotic translation initiation factor 4E-2; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome [...]
anp1 protein networkhttps://string-db.org/network/284812.O74745Mannan polymerase II complex anp1 subunit; The M-Pol II complex possesses alpha-1,6-mannosyltransferase activity and is probably involved in the elongation of the mannan backbone of N-linked glyc [...]
spf31 protein networkhttps://string-db.org/network/284812.O74746J domain-containing protein spf31.
rhp18 protein networkhttps://string-db.org/network/284812.O74747Postreplication repair E3 ubiquitin-protein ligase rad18; E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme ubc2/rad6 to form the [...]
trs8502 protein networkhttps://string-db.org/network/284812.O74748Transport protein particle subunit trs85-2; Component of the TRAPP I and TRAPP II complexes. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II seems [...]
hse1 protein networkhttps://string-db.org/network/284812.O74749Class E vacuolar protein-sorting machinery protein hse1; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
yea4 protein networkhttps://string-db.org/network/284812.O74750UDP-N-acetylglucosamine transporter yea4; Sugar transporter that specifically mediates the transport of UDP-N-acetylglucosamine (UDP-GlcNAc) and is required for cell wall chitin synthesis; Belong [...]
ipa1 protein networkhttps://string-db.org/network/284812.O74751Uncharacterized protein C1734.10c.
mas5 protein networkhttps://string-db.org/network/284812.O74752Mitochondrial protein import protein mas5; Probably involved in mitochondrial protein import (By similarity). Plays a role in microtubule cytoskeleton organization.
atp3 protein networkhttps://string-db.org/network/284812.O74754ATP synthase subunit gamma, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane [...]
pst3 protein networkhttps://string-db.org/network/284812.O74755Paired amphipathic helix protein pst3.
chs2 protein networkhttps://string-db.org/network/284812.O74756Chitin synthase-like protein 2; Plays a role in septum formation. Has no chitin synthase activity; Belongs to the chitin synthase family.
hrd1 protein networkhttps://string-db.org/network/284812.O74757ERAD-associated E3 ubiquitin-protein ligase hrd1; E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated E2 ligases, and transfers it to substrates [...]
nto1 protein networkhttps://string-db.org/network/284812.O74759Mst2 complex subunit nto1; Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3K14 ace [...]
tif301 protein networkhttps://string-db.org/network/284812.O74760Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a speciali [...]
spp2 protein networkhttps://string-db.org/network/284812.O74761DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
rpn2 protein networkhttps://string-db.org/network/284812.O7476226S proteasome regulatory subunit rpn2; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
dca7 protein networkhttps://string-db.org/network/284812.O74763Uncharacterized WD repeat-containing protein C17D11.08.
spb4 protein networkhttps://string-db.org/network/284812.O74764ATP-dependent rRNA helicase spb4; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles [...]
SPBC24C6.03 protein networkhttps://string-db.org/network/284812.O74765Probable proline--tRNA ligase, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family.
put2 protein networkhttps://string-db.org/network/284812.O74766Probable delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
sec28 protein networkhttps://string-db.org/network/284812.O74767Probable coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further medi [...]
bhd1 protein networkhttps://string-db.org/network/284812.O74769Folliculin-like protein bhd1.
SPBC24C6.09c protein networkhttps://string-db.org/network/284812.O74770Probable phosphoketolase.
dip1 protein networkhttps://string-db.org/network/284812.O74771Protein dip1; May be involved in protein-linked oligosaccharide phosphorylation; Belongs to the LDB17 family.
cwf14 protein networkhttps://string-db.org/network/284812.O74772Pre-mRNA-splicing factor cwf14; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
msh2 protein networkhttps://string-db.org/network/284812.O74773DNA mismatch repair protein msh2; Involved in post-replicative DNA-mismatch repair. Binds to mismatch-containing DNA. Required for correct termination of copy synthesis during mating-type switchi [...]
hbs1 protein networkhttps://string-db.org/network/284812.O74774Elongation factor 1 alpha-like protein; Involved in protein translation. Together with dom34, may function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a [...]
SPBC25B2.03 protein networkhttps://string-db.org/network/284812.O74775Protein sip5; May negatively regulate the snf1 kinase; Belongs to the SIP5 family.
mtg1 protein networkhttps://string-db.org/network/284812.O74776Mitochondrial GTPase 1; Mitochondrial GTPase involved in assembly of the large ribosomal subunit (By similarity). Plays a role in expression of the mitochondrial translational machinery (By simil [...]
mis3 protein networkhttps://string-db.org/network/284812.O74777KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
btb2 protein networkhttps://string-db.org/network/284812.O74778BTB/POZ domain-containing protein 2; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of tar [...]
mmb1 protein networkhttps://string-db.org/network/284812.O74779Microtubule-associated protein mug164; Involved in the cell polarity process and in regulation of microtubule growth. Has a role in meiosis.
SPBC25B2.08 protein networkhttps://string-db.org/network/284812.O74780Uncharacterized protein C25B2.08.
mrs1 protein networkhttps://string-db.org/network/284812.O74781Probable arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.
SPBC25B2.10 protein networkhttps://string-db.org/network/284812.O74782Universal stress protein A family protein C25B2.10.
pof2 protein networkhttps://string-db.org/network/284812.O74783SCF E3 ubiquitin ligase complex F-box protein pof2; Involved in substrate recognition in ubiquitin-dependent degradation.
sec9 protein networkhttps://string-db.org/network/284812.O74786Protein transport protein sec9; Has a role in cell separation, a final step of cytokinesis and in the assembly of the forespore membrane. May have a role in the transport of secretory proteins to [...]
cho2 protein networkhttps://string-db.org/network/284812.O74787Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (P [...]
iml1 protein networkhttps://string-db.org/network/284812.O74788Vacuolar membrane-associated protein iml1.
pph3 protein networkhttps://string-db.org/network/284812.O74789Putative serine/threonine-protein phosphatase C26H8.05c; Belongs to the PPP phosphatase family. PP-1 subfamily.
grx4 protein networkhttps://string-db.org/network/284812.O74790Monothiol glutaredoxin-4; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters (By similarity). Binds one iron-sulfur cluster per dimer. The iron-sulfur cluster is bound bet [...]
grn1 protein networkhttps://string-db.org/network/284812.O74791GTPase grn1; Required for optimal growth. Required for normal processing of ribosomal pre-rRNA. Required for nuclear export of ribosomal protein rpl2501; Belongs to the TRAFAC class YlqF/YawG GTP [...]
snf59 protein networkhttps://string-db.org/network/284812.O74792SWI/SNF global transcription activator complex subunit snf59; Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regu [...]
the4 protein networkhttps://string-db.org/network/284812.O74793Uncharacterized protein C26H8.11c.
cyc3 protein networkhttps://string-db.org/network/284812.O74794Putative cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c.
orc6 protein networkhttps://string-db.org/network/284812.O74796Origin recognition complex subunit 6; Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcript [...]
ess1 protein networkhttps://string-db.org/network/284812.O74797UPF0587 protein C2D10.03c; Belongs to the UPF0587 family.
aly2 protein networkhttps://string-db.org/network/284812.O74798Putative arrestin-related trafficking adapter C2D10.04; May regulate endocytosis in response to extracellular stimuli; Belongs to the ALY1 family.
exg3 protein networkhttps://string-db.org/network/284812.O74799Glucan 1,3-beta-glucosidase 3.
mmp1 protein networkhttps://string-db.org/network/284812.O74800Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into th [...]
yml6 protein networkhttps://string-db.org/network/284812.O7480154S ribosomal protein yml6, mitochondrial; Belongs to the universal ribosomal protein uL4 family.
snr1 protein networkhttps://string-db.org/network/284812.O748023-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has an indirect role in endocytic membrane trafficking. May have a function [...]
rhp23 protein networkhttps://string-db.org/network/284812.O74803UV excision repair protein rhp23; Involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA.
est1 protein networkhttps://string-db.org/network/284812.O74804Telomere elongation protein est1; Directly involved in telomere replication. Associates with telomerase and during its interaction with trt1, telomerase activity is promoted; Belongs to the EST1 [...]
myo51 protein networkhttps://string-db.org/network/284812.O74805Myosin-51; Involved in cytokinesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
pth1 protein networkhttps://string-db.org/network/284812.O74806Probable peptidyl-tRNA hydrolase; Belongs to the PTH family.
mhf1 protein networkhttps://string-db.org/network/284812.O74807Inner kinetochore subunit mhf1; dsDNA-binding component of a FANCM-MHF complex involved in DNA damage repair and genome maintenance. FANCM-MHF promotes gene conversion at blocked replication fork [...]
clr1 protein networkhttps://string-db.org/network/284812.O74808Cryptic loci regulator protein 1; Regulates silencing of the mat2 and mat3 loci. Organizes the chromatin structure of the mating-type region where it also participates in establishing the 'cold s [...]
alb1 protein networkhttps://string-db.org/network/284812.O74809Uncharacterized protein C2D10.19c.
ubc1 protein networkhttps://string-db.org/network/284812.O74810Ubiquitin-conjugating enzyme E2 1; Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in degradation of misfolded or regulated proteins localized in the endoplasmic retic [...]
rhn1 protein networkhttps://string-db.org/network/284812.O74814UPF0400 protein C337.03; Belongs to the UPF0400 (RTT103) family.
ppk27 protein networkhttps://string-db.org/network/284812.O74815Serine/threonine-protein kinase ppk27.
ecm14 protein networkhttps://string-db.org/network/284812.O74818Uncharacterized carboxypeptidase C337.07c; Belongs to the peptidase M14 family.
erg28 protein networkhttps://string-db.org/network/284812.O74820Ergosterol biosynthetic protein 28; May have a role in anchoring erg26 and erg27 to the endoplasmic reticulum. May also be responsible for facilitating their interaction (By similarity); Belongs [...]
dre2 protein networkhttps://string-db.org/network/284812.O74821Fe-S cluster assembly protein dre2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an elec [...]
SPBC337.11 protein networkhttps://string-db.org/network/284812.O74822Zinc-type alcohol dehydrogenase-like protein C337.11.
red5 protein networkhttps://string-db.org/network/284812.O74823Zinc finger CCCH domain-containing protein C337.12.
gtr1 protein networkhttps://string-db.org/network/284812.O74824GTP-binding protein gtr1; GTPase. Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome (By similarity).
rpb4 protein networkhttps://string-db.org/network/284812.O74825DNA-directed RNA polymerase II subunit rpb4; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
coq7 protein networkhttps://string-db.org/network/284812.O748265-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural rol [...]
cho1 protein networkhttps://string-db.org/network/284812.O74827Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidyl [...]
esf1 protein networkhttps://string-db.org/network/284812.O74828Pre-rRNA-processing protein esf1; Involved in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF1 family.
SPCC1183.02 protein networkhttps://string-db.org/network/284812.O74830Putative glutathione S-transferase C1183.02; Involved in the oxidative stress response and detoxification.
fxn1 protein networkhttps://string-db.org/network/284812.O74831Frataxin homolog, mitochondrial; Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play [...]
pet127 protein networkhttps://string-db.org/network/284812.O74832mRNA degradation protein pet127, mitochondrial; Required for the degradation of mRNA in mitochondria. Belongs to the PET127 family.
lig4 protein networkhttps://string-db.org/network/284812.O74833DNA ligase 4; Involved in ds DNA break repair. Belongs to the ATP-dependent DNA ligase family.
ung1 protein networkhttps://string-db.org/network/284812.O74834Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
rrp5 protein networkhttps://string-db.org/network/284812.O74835rRNA biogenesis protein rrp5; Involved in the biogenesis of rRNA. Required for the formation of 18S and 5.8S rRNA (By similarity).
rpl101 protein networkhttps://string-db.org/network/284812.O7483660S ribosomal protein L1-B.
pmp31 protein networkhttps://string-db.org/network/284812.O74837Plasma membrane proteolipid 31; Has a role in meiosis; Belongs to the UPF0057 (PMP3) family.
wtf10 protein networkhttps://string-db.org/network/284812.O74838Uncharacterized protein wtf10.
msy1 protein networkhttps://string-db.org/network/284812.O74839Mechanosensitive ion channel protein Msy1; Regulates intracellular calcium levels and cell volume for survival in response to hypo-osmotic shock. Acts as a mechanosensitive calcium channel in res [...]
cue2 protein networkhttps://string-db.org/network/284812.O74840Smr domain-containing protein C1235.03.
nad1 protein networkhttps://string-db.org/network/284812.O74841Probable FAD synthase; Adenylates FMN to FAD.
fft2 protein networkhttps://string-db.org/network/284812.O74842ATP-dependent helicase fft2; DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is required for heterochromatin organization.
get2 protein networkhttps://string-db.org/network/284812.O74843Sad1-interacting factor 1.
fta7 protein networkhttps://string-db.org/network/284812.O74844Inner kinetochore subunit fta7; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segre [...]
hif2 protein networkhttps://string-db.org/network/284812.O74845Set3 complex subunit hif2; Component of the set3 histone deacetylase complex which is involved in chromatin remodeling and transcription regulation, such as repression of the sporulation gene pro [...]
sec6 protein networkhttps://string-db.org/network/284812.O74846Exocyst complex component sec6; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
mpc1 protein networkhttps://string-db.org/network/284812.O74847Probable mitochondrial pyruvate carrier 1; Mediates the uptake of pyruvate into mitochondria.
mug146 protein networkhttps://string-db.org/network/284812.O74848Meiotically up-regulated gene 146 protein; Has a role in sporulation.
ght6 protein networkhttps://string-db.org/network/284812.O74849High-affinity fructose transporter ght6; High-affinity fructose transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
dga1 protein networkhttps://string-db.org/network/284812.O74850Diacylglycerol O-acyltransferase 1; Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Cells defective in triacy [...]
adg3 protein networkhttps://string-db.org/network/284812.O74851Probable secreted beta-glucosidase adg3; Cell surface beta-glucosidase involved in cell wall biogenesis,; Belongs to the SUN family.
SPCC18.02 protein networkhttps://string-db.org/network/284812.O74852Uncharacterized MFS-type transporter C18.02.
SPCC18.03 protein networkhttps://string-db.org/network/284812.O74853FKBP12-associated protein 1 homolog; May play a role in transcription regulation; Belongs to the NFX1 family.
pof6 protein networkhttps://string-db.org/network/284812.O74854F-box protein pof6; Together with skp1, essential for septum processing and cell separation.
rsa4 protein networkhttps://string-db.org/network/284812.O74855Ribosome assembly protein 4; Involved in ribosome biogenesis. Required for processing and efficient intra-nuclear transport of pre-60S ribosomal subunits. Interacts with the AAA-ATPase Midasin, w [...]
caf1 protein networkhttps://string-db.org/network/284812.O74856Poly(A) ribonuclease pop2; Acts as the catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deade [...]
rpc53 protein networkhttps://string-db.org/network/284812.O74857DNA-directed RNA polymerase III subunit rpc4; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripher [...]
msk1 protein networkhttps://string-db.org/network/284812.O74858Lysine--tRNA ligase, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family.
hnt3 protein networkhttps://string-db.org/network/284812.O74859Aprataxin-like protein; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates forme [...]
SPCC18.10 protein networkhttps://string-db.org/network/284812.O74860Putative pyridoxal kinase C18.10; Required for synthesis of pyridoxal-5-phosphate from vitamin B6; Belongs to the pyridoxine kinase family.
sdc1 protein networkhttps://string-db.org/network/284812.O74861Set1 complex component sdc1; The COMPASS (Set1C) complex specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently activates gene expression by regulating trans [...]
utp23 protein networkhttps://string-db.org/network/284812.O74862rRNA-processing protein utp23; Involved in rRNA-processing and ribosome biogenesis. Belongs to the UTP23/FCF1 family. UTP23 subfamily.
trm82 protein networkhttps://string-db.org/network/284812.O74863tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit trm82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize an [...]
rpp0 protein networkhttps://string-db.org/network/284812.O7486460S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
dph7 protein networkhttps://string-db.org/network/284812.O74865Diphthine methyltransferase; Catalyzes the demethylation of diphthine methyl ester to form diphthine, an intermediate in diphthamide biosynthesis, a post- translational modification of histidine [...]
fmn1 protein networkhttps://string-db.org/network/284812.O74866Riboflavin kinase; Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.
SPCC18.17c protein networkhttps://string-db.org/network/284812.O74867Uncharacterized protein C18.17c.
nic1 protein networkhttps://string-db.org/network/284812.O74869High-affinity nickel transport protein nic1; High-affinity nickel transporter responsible for nickel uptake. Required for urease biosynthesis. Belongs to the NiCoT transporter (TC 2.A.52) family.
mug73 protein networkhttps://string-db.org/network/284812.O74870Meiotically up-regulated gene 73 protein; Has a role in meiosis; Belongs to the archaeal/bacterial/fungal opsin family.
mlo1 protein networkhttps://string-db.org/network/284812.O74871Uncharacterized protein C31H12.03c.
sec231 protein networkhttps://string-db.org/network/284812.O74873Protein transport protein sec23-1; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main f [...]
ccr4 protein networkhttps://string-db.org/network/284812.O74874Glucose-repressible alcohol dehydrogenase transcriptional effector; Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and [...]
SPCC330.03c protein networkhttps://string-db.org/network/284812.O74875Uncharacterized heme-binding protein C330.03c.
mug135 protein networkhttps://string-db.org/network/284812.O74876Meiotically up-regulated gene 135 protein; Has a role in meiosis; Belongs to the UPF0612 family.
alg11 protein networkhttps://string-db.org/network/284812.O74878GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core [...]
enp2 protein networkhttps://string-db.org/network/284812.O74879Ribosome biogenesis protein enp2 homolog; May be involved in rRNA-processing and ribosome biosynthesis.
pcm1 protein networkhttps://string-db.org/network/284812.O74880mRNA cap guanine-N7 methyltransferase; Responsible for methylating the 5'-cap structure of mRNAs. Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransfera [...]
btb1 protein networkhttps://string-db.org/network/284812.O74881BTB/POZ domain-containing protein 1; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of tar [...]
sdh3 protein networkhttps://string-db.org/network/284812.O74882Succinate dehydrogenase cytochrome B subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport cha [...]
rpc37 protein networkhttps://string-db.org/network/284812.O74883DNA-directed RNA polymerase III subunit rpc5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripher [...]
rpl2402 protein networkhttps://string-db.org/network/284812.O7488460S ribosomal protein L24-B.
xan1 protein networkhttps://string-db.org/network/284812.O74885Alpha-ketoglutarate-dependent xanthine dioxygenase xan1; Alpha-ketoglutarate-dependent xanthine dioxygenase is a non- heme mononuclear Fe(2+) enzyme that decarboxylates alpha-ketoglutarate to suc [...]
SPCC576.02 protein networkhttps://string-db.org/network/284812.O74886Uncharacterized protein C576.02.
tpx1 protein networkhttps://string-db.org/network/284812.O74887Peroxiredoxin tpx1; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection aga [...]
bxi1 protein networkhttps://string-db.org/network/284812.O74888Bax inhibitor 1; Links the unfolded protein response and programmed cell death and mediates mitochondrial-dependent apoptosis. Induces cell death and disruption of the mitochondrial transmembrane [...]
sac3 protein networkhttps://string-db.org/network/284812.O74889SAC3 family protein 1.
SPCC576.06c protein networkhttps://string-db.org/network/284812.O74890Tyrosine--tRNA ligase, mitochondrial; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acc [...]
ret3 protein networkhttps://string-db.org/network/284812.O74891Probable coatomer subunit zeta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate [...]
rps2 protein networkhttps://string-db.org/network/284812.O7489240S ribosomal protein S2.
rps20 protein networkhttps://string-db.org/network/284812.O7489340S ribosomal protein S20; Belongs to the universal ribosomal protein uS10 family.
rpt3 protein networkhttps://string-db.org/network/284812.O7489426S proteasome regulatory subunit 6B homolog; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency [...]
rpl15 protein networkhttps://string-db.org/network/284812.O7489560S ribosomal protein L15-A.
mhf2 protein networkhttps://string-db.org/network/284812.O74896Inner kinetochore subunit mhf2; dsDNA-binding component of a FANCM-MHF complex involved in DNA damage repair and genome maintenance. FANCM-MHF promotes gene conversion at blocked replication fork [...]
swc5 protein networkhttps://string-db.org/network/284812.O74897SWR1-complex protein 5; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by [...]
dph5 protein networkhttps://string-db.org/network/284812.O74898Diphthine methyl ester synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 ( [...]
SPCC613.03 protein networkhttps://string-db.org/network/284812.O74903Uncharacterized calcium-binding protein C613.03.
rpl35 protein networkhttps://string-db.org/network/284812.O7490460S ribosomal protein L35; Belongs to the universal ribosomal protein uL29 family.
rpl902 protein networkhttps://string-db.org/network/284812.O7490560S ribosomal protein L9-B.
bcd1 protein networkhttps://string-db.org/network/284812.O74906Putative box C/D snoRNA protein SPCC613.07; Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis. Belongs to the BCD1 [...]
SPCC613.08 protein networkhttps://string-db.org/network/284812.O74907Protein bcp1; Involved in nuclear export, actin cytoskeleton organization and vesicular transport; Belongs to the BCP1 family.
sen54 protein networkhttps://string-db.org/network/284812.O74908Probable tRNA-splicing endonuclease subunit sen54; Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pr [...]
meu23 protein networkhttps://string-db.org/network/284812.O74909Meiotic expression up-regulated protein 23; Belongs to the UPF0612 family.
raf1 protein networkhttps://string-db.org/network/284812.O74910Rik1-associated factor 1; Component of the rik1-associated E3 ubiquitin ligase complex that shows ubiquitin ligase activity and is required for histone H3K9 methylation. H3K9me represents a speci [...]
SPCC757.02c protein networkhttps://string-db.org/network/284812.O74913Uncharacterized protein C757.02c.
hsp3101 protein networkhttps://string-db.org/network/284812.O74914Glutathione-independent glyoxalase hsp3101; Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step. May play a role in detoxifying endogenously [...]
SPCC757.04 protein networkhttps://string-db.org/network/284812.O74915Uncharacterized transcriptional regulatory protein C757.04.
SPCC757.05c protein networkhttps://string-db.org/network/284812.O74916Peptidase M20 domain-containing protein C757.05c; Belongs to the peptidase M20A family.
rrp45 protein networkhttps://string-db.org/network/284812.O74918Exosome complex component rrp45; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrad [...]
rnc1 protein networkhttps://string-db.org/network/284812.O74919RNA-binding protein rnc1; Binds and stabilizes pmp1 mRNA and hence acts as a negative regulator of pmk1 signaling. Overexpression suppresses the Cl(-) sensitivity of calcineurin deletion.
vph2 protein networkhttps://string-db.org/network/284812.O74920Vacuolar ATPase assembly integral membrane protein vph2; Required for vacuolar ATPase assembly.
aah1 protein networkhttps://string-db.org/network/284812.O74922Alpha-amylase 1.
SPCC757.13 protein networkhttps://string-db.org/network/284812.O74923Uncharacterized transporter C757.13.
pep3 protein networkhttps://string-db.org/network/284812.O74925Vacuolar membrane protein pep3; Required for vacuolar biogenesis; Belongs to the VPS18 family.
rbd2 protein networkhttps://string-db.org/network/284812.O74926Rhomboid protein 2; Probable serine protease; Belongs to the peptidase S54 family.
met11 protein networkhttps://string-db.org/network/284812.O74927Methylenetetrahydrofolate reductase 2; Major methylenetetrahydrofolate reductase required to generate the methyl groups necessary for methionine synthetase to convert homocysteine to methionine. [...]
ade10 protein networkhttps://string-db.org/network/284812.O74928Phosphoribosylaminoimidazolecarboxamide formyltransferase; Belongs to the PurH family.
dbl2 protein networkhttps://string-db.org/network/284812.O74939Uncharacterized protein C553.01c.
qns1 protein networkhttps://string-db.org/network/284812.O74940Putative glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
pex1 protein networkhttps://string-db.org/network/284812.O74941Peroxisomal ATPase pex1; Component of the peroxisomal protein import machinery. Together with pex6, mediates the ATP-dependent relocation and recycling of the peroxisomal targeting signal-1 (PTS1 [...]
cyp9 protein networkhttps://string-db.org/network/284812.O74942Peptidyl-prolyl cis-trans isomerase 9; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
swp1 protein networkhttps://string-db.org/network/284812.O74943Uncharacterized protein C553.06.
kpa1 protein networkhttps://string-db.org/network/284812.O74944DNA polymerase kappa; DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA s [...]
ria1 protein networkhttps://string-db.org/network/284812.O74945Ribosome assembly protein 1; GTPase involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with sdo1, may trigger the GTP-dependent release of [...]
spb70 protein networkhttps://string-db.org/network/284812.O74946DNA polymerase alpha subunit B; May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery [...]
knh3 protein networkhttps://string-db.org/network/284812.O74947Uncharacterized protein C553.10.
toa2 protein networkhttps://string-db.org/network/284812.O74948Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a compl [...]
SPCC736.02 protein networkhttps://string-db.org/network/284812.O74951Uncharacterized protein C736.02.
msf1 protein networkhttps://string-db.org/network/284812.O74952Phenylalanine--tRNA ligase, mitochondrial; Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation.
cbf11 protein networkhttps://string-db.org/network/284812.O74954Transcription factor cbf11; Transcription factor that behaves as a negative regulator of adhesion. Recognizes specifically the canonical CSL response element GTGA/GGAA. May also play a cbf12-anta [...]
tfx1 protein networkhttps://string-db.org/network/284812.O74955Translin-associated protein X homolog; Belongs to the translin family.
mrps8 protein networkhttps://string-db.org/network/284812.O7495637S ribosomal protein subunit S8, mitochondrial; Belongs to the universal ribosomal protein uS8 family.
ago1 protein networkhttps://string-db.org/network/284812.O74957Protein argonaute; Required for G1 arrest and mating in response to nitrogen starvation. Ago1 regulation of cytokinesis and cell cycle checkpoints occurs downstream of dcr1. Required, indirectly, [...]
mmi1 protein networkhttps://string-db.org/network/284812.O74958YTH domain-containing protein mmi1; RNA-binding protein that recognizes and binds N6- methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding [...]
SPCC736.13 protein networkhttps://string-db.org/network/284812.O74959Uncharacterized oxidoreductase C736.13; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
pil1 protein networkhttps://string-db.org/network/284812.O74960Probable sphingolipid long chain base-responsive protein pil1; Negative regulator of cell wall integrity (CWI) in unstressed cells, probably by inhibiting protein kinase ksg1/ppk21 activity and r [...]
ptk1 protein networkhttps://string-db.org/network/284812.O74962Pantothenate kinase; Plays a role in the physiological regulation of the intracellular CoA concentration.
nca2 protein networkhttps://string-db.org/network/284812.O74963Nuclear control of ATPase protein 2; Involved in the mitochondrial expression of subunits 6 and 8 of the F0-F1 ATP synthase; Belongs to the NCA2 family.
rsc1 protein networkhttps://string-db.org/network/284812.O74964Chromatin structure-remodeling complex subunit rsc1; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Contr [...]
eif21 protein networkhttps://string-db.org/network/284812.O74965Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S riboso [...]
smg1 protein networkhttps://string-db.org/network/284812.O74966Small nuclear ribonucleoprotein G; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site (By similarity).
vps25 protein networkhttps://string-db.org/network/284812.O74967Vacuolar protein-sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation [...]
usp102 protein networkhttps://string-db.org/network/284812.O74968U1 small nuclear ribonucleoprotein usp102; Involved in nuclear mRNA splicing.
ght2 protein networkhttps://string-db.org/network/284812.O74969High-affinity glucose transporter ght2; High-affinity glucose transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
usp105 protein networkhttps://string-db.org/network/284812.O74970Pre-mRNA-processing factor 39; Function prior to stable branch point recognition by the U1 snRNP particle to facilitate or stabilize the U1 snRNP/5'-splice site interaction. Has a direct role in [...]
atg5 protein networkhttps://string-db.org/network/284812.O74971Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nit [...]
fyv4 protein networkhttps://string-db.org/network/284812.O74972Protein fyv4, mitochondrial; Involved in telomere length regulation; Belongs to the mitochondrion-specific ribosomal protein mS41 family.
utp25 protein networkhttps://string-db.org/network/284812.O74974U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
pcy1 protein networkhttps://string-db.org/network/284812.O74975Probable choline-phosphate cytidylyltransferase; Belongs to the cytidylyltransferase family.
pcs60 protein networkhttps://string-db.org/network/284812.O74976Putative peroxisomal-coenzyme A synthetase.
vms1 protein networkhttps://string-db.org/network/284812.O74977VMS1 homolog C1827.04; Involved in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. Component of an evolutionarily conserved system for ubiquitin-mediated mitochondria-associ [...]
SPCC1827.05c protein networkhttps://string-db.org/network/284812.O74978Uncharacterized RNA-binding protein C1827.05c.
mug112 protein networkhttps://string-db.org/network/284812.O74981Meiotically up-regulated gene 112 protein; Has a role in meiosis.
mix23 protein networkhttps://string-db.org/network/284812.O74982Caffeine-induced death protein 2.
mms2 protein networkhttps://string-db.org/network/284812.O74983Ubiquitin-conjugating enzyme spm2; Has a role in the DNA error-free postreplication repair (PRR) pathway. Lacks catalytic activity by itself. The ubc13/spm2 heterodimer catalyzes the synthesis of [...]
SPCC338.06c protein networkhttps://string-db.org/network/284812.O74984Heat shock protein homolog C338.06c.
naa15 protein networkhttps://string-db.org/network/284812.O74985N-terminal acetyltransferase A complex subunit nat1; Non-catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and [...]
ctp1 protein networkhttps://string-db.org/network/284812.O74986DNA endonuclease ctp1; Endonuclease that cooperates with the MRN complex in processing meiotic and mitotic double-strand breaks by allowing the endonucleolytic removal of rec12 from the break sit [...]
cox5 protein networkhttps://string-db.org/network/284812.O74988Cytochrome c oxidase polypeptide 5, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The [...]
pbi2 protein networkhttps://string-db.org/network/284812.O74989Uncharacterized protein C338.12.
cog4 protein networkhttps://string-db.org/network/284812.O74990Conserved oligomeric Golgi complex subunit 4; Component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis- Golgi, and regulates [...]
pof3 protein networkhttps://string-db.org/network/284812.O74991F-box/TPR repeat protein pof3; Has a role in substrate recognition in the Skp1-Cullin- 1/Cdc53-F-box (SCF) ubiquitin ligase complex. Required for the maintenance of telomere length and transcript [...]
SPCC338.18 protein networkhttps://string-db.org/network/284812.O74992Uncharacterized membrane protein C338.18.
rng3 protein networkhttps://string-db.org/network/284812.O74994Ring assembly protein 3; Essential for actinomyosin ring assembly during cytokinesis. Has a role, in conjunction with F-actin, in assembling myosin II- containing proteins, such as myo2, at the d [...]
ssl1 protein networkhttps://string-db.org/network/284812.O74995General transcription and DNA repair factor IIH subunit ssl1; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription [...]
rhp7 protein networkhttps://string-db.org/network/284812.O74999DNA repair protein rhp7; Involved in global genome repair (GGR) via nucleotide excision repair (NER), in conjunction with rhp16, after UV irradiation. Belongs to the RAD7 family.
mcm7 protein networkhttps://string-db.org/network/284812.O75001DNA replication licensing factor mcm7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiat [...]
mog1 protein networkhttps://string-db.org/network/284812.O75002Nuclear import protein mog1; Involved in the Ran-GTPase system for nuclear protein import and poly(A)+ mRNA export. Required for mitosis-to-interphase transition; Belongs to the MOG1 family.
cdc24 protein networkhttps://string-db.org/network/284812.O75004Cell division control protein 24; Has a role in the progression of DNA replication and in the maintenance of genomic integrity. Acts during S phase, after initiation, where it is essential for co [...]
vrs1 protein networkhttps://string-db.org/network/284812.O75005Valine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
sec15 protein networkhttps://string-db.org/network/284812.O75006Exocyst complex component sec15; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane; Belongs to the SEC15 family.
nak1 protein networkhttps://string-db.org/network/284812.O75011Serine/threonine-protein kinase nak1; Has a role in the regulation of cell polarity, growth and division.
mph1 protein networkhttps://string-db.org/network/284812.O94235Serine/threonine-protein kinase mph1; Involved in the regulation of the onset of mitosis. Involved in a pathway that coordinates cell proliferation and differentiation. Belongs to the protein kin [...]
moe1 protein networkhttps://string-db.org/network/284812.O94236Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a spe [...]
rpl14 protein networkhttps://string-db.org/network/284812.O9423860S ribosomal protein L14; Belongs to the eukaryotic ribosomal protein eL14 family.
arp6 protein networkhttps://string-db.org/network/284812.O94241Actin-like protein arp6; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes b [...]
dar2 protein networkhttps://string-db.org/network/284812.O94242Aspartate--tRNA ligase, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
mug9 protein networkhttps://string-db.org/network/284812.O94243Meiotically up-regulated gene 9 protein; Has a role in meiosis.
mis16 protein networkhttps://string-db.org/network/284812.O94244Histone acetyltransferase type B subunit 2; Regulatory subunit of the histone acetylase B (HAT-B) complex (By similarity). The complex acetylates 'Lys-12' of histone H4 which is required for telo [...]
SPCC737.04 protein networkhttps://string-db.org/network/284812.O94245UPF0300 protein C737.04.
gcs2 protein networkhttps://string-db.org/network/284812.O94246Putative glutamate--cysteine ligase regulatory subunit.
SPCC737.07c protein networkhttps://string-db.org/network/284812.O94247DNA polymerase alpha-associated DNA helicase A; DNA polymerase alpha-associated DNA helicase which may be involved in DNA replication; Belongs to the DNA2/NAM7 helicase family.
mdn1 protein networkhttps://string-db.org/network/284812.O94248Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits. Functions at successive maturation steps to remove ribosomal factors at critical transition poi [...]
SPCC13B11.03c protein networkhttps://string-db.org/network/284812.O94250Probable hydroxyacylglutathione hydrolase C13B11.03c; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
pop7 protein networkhttps://string-db.org/network/284812.O94251Ribonucleases P/MRP protein subunit POP7; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP, which cleav [...]
rng9 protein networkhttps://string-db.org/network/284812.O94252Uncharacterized protein P8B7.02.
mug45 protein networkhttps://string-db.org/network/284812.O94254Meiotically up-regulated gene 45 protein; Has a role in meiosis.
nce103 protein networkhttps://string-db.org/network/284812.O94255Carbonic anhydrase; Catalyzes the reversible hydration of CO(2) to H(2)CO(3). The main role may be to provide inorganic carbon for the bicarbonate- dependent carboxylation reactions catalyzed by [...]
set6 protein networkhttps://string-db.org/network/284812.O94256SET domain and MYND-type zinc finger protein 6.
ppm1 protein networkhttps://string-db.org/network/284812.O94257Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs t [...]
los1 protein networkhttps://string-db.org/network/284812.O94258Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA wit [...]
utp16 protein networkhttps://string-db.org/network/284812.O94259Probable U3 small nucleolar RNA-associated protein 16; Involved in nucleolar processing of pre-18S ribosomal RNA.
nxt3 protein networkhttps://string-db.org/network/284812.O94260Putative G3BP-like protein; Probable scaffold protein that may be involved in mRNA transport.
fta3 protein networkhttps://string-db.org/network/284812.O94261Inner kinetochore subunit fta3; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segre [...]
vac7 protein networkhttps://string-db.org/network/284812.O94262Vacuolar segregation protein 7; Component of the PI(3,5)P2 regulatory complex that regulates both the synthesis and turnover of phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2). Directly in [...]
dpb2 protein networkhttps://string-db.org/network/284812.O94263DNA polymerase epsilon subunit B; As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication. Belongs to the DNA polymerase epsilon subun [...]
mpe1 protein networkhttps://string-db.org/network/284812.O94264Uncharacterized RING finger protein P8B7.15c.
SPBP8B7.17c protein networkhttps://string-db.org/network/284812.O94265Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 1; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the N-terminal sec [...]
SPBP8B7.18c protein networkhttps://string-db.org/network/284812.O94266Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 2; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the N-terminal sec [...]
spt16 protein networkhttps://string-db.org/network/284812.O94267FACT complex subunit spt16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a [...]
nop2 protein networkhttps://string-db.org/network/284812.O9426825S rRNA (cytosine-C(5))-methyltransferase nop2; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of a cytosine in 25S rRNA. Required for 60S rib [...]
ubp3 protein networkhttps://string-db.org/network/284812.O94269Probable ubiquitin carboxyl-terminal hydrolase 3.
erd2 protein networkhttps://string-db.org/network/284812.O94270ER lumen protein-retaining receptor; Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for [...]
rnf10 protein networkhttps://string-db.org/network/284812.O94271Uncharacterized RING finger protein P8B7.23.
atg8 protein networkhttps://string-db.org/network/284812.O94272Autophagy-related protein 8; Ubiquitin-like modifier involved in autophagosomes formation. With atg4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. [...]
cyp4 protein networkhttps://string-db.org/network/284812.O94273Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belon [...]
SPBP8B7.26 protein networkhttps://string-db.org/network/284812.O94274Uncharacterized protein P8B7.26.
mug30 protein networkhttps://string-db.org/network/284812.O94275Probable E3 ubiquitin-protein ligase mug30; Probable E3 ubiquitin-protein ligase. Has a role in meiosis.
stc1 protein networkhttps://string-db.org/network/284812.O94276Meiotic chromosome segregation protein P8B7.28c; Required for meiotic chromosome segregation.
abz1 protein networkhttps://string-db.org/network/284812.O94277Putative aminodeoxychorismate synthase; Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine. Required for the synthesis of 4- aminobenzoate (PABA), an impo [...]
thi5 protein networkhttps://string-db.org/network/284812.O94278Thiamine repressible genes regulatory protein thi5; Transcription factor that activates the nmt1 promoter. Regulation of thiamine repressible genes. Negatively regulates conjugation during meiosi [...]
SPBP8B7.31 protein networkhttps://string-db.org/network/284812.O94279Putative magnesium-dependent phosphatase P8B7.31; Magnesium-dependent phosphatase which may act as a tyrosine phosphatase.
SPBC2G5.01 protein networkhttps://string-db.org/network/284812.O94280UPF0674 endoplasmic reticulum membrane protein C2G5.01.
ckb2 protein networkhttps://string-db.org/network/284812.O94281Probable casein kinase II subunit beta-2; Plays a complex role in regulating the basal catalytic activity of the alpha subunit.
ctu1 protein networkhttps://string-db.org/network/284812.O94282Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts [...]
erv41 protein networkhttps://string-db.org/network/284812.O94283ER-derived vesicles protein 41; Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Faci [...]
hmt2 protein networkhttps://string-db.org/network/284812.O94284Sulfide:quinone oxidoreductase, mitochondrial; Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone.
rpc25 protein networkhttps://string-db.org/network/284812.O94285DNA-directed RNA polymerase III subunit rpc8; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripher [...]
adi1 protein networkhttps://string-db.org/network/284812.O942861,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
SPBC887.02 protein networkhttps://string-db.org/network/284812.O94287Uncharacterized chloride channel protein C887.02; Voltage-gated chloride channel; Belongs to the chloride channel (TC 2.A.49) family.
noc3 protein networkhttps://string-db.org/network/284812.O94288Nucleolar complex-associated protein 3; May be required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 [...]
lub1 protein networkhttps://string-db.org/network/284812.O94289Ubiquitin homeostasis protein lub1; Acts as a negative regulator of vacuole-dependent ubiquitin degradation.
cwf29 protein networkhttps://string-db.org/network/284812.O94290U2 snRNP component ist3; Required for pre-mRNA splicing and spliceosome assembly.
snx3 protein networkhttps://string-db.org/network/284812.O94291Sorting nexin-3; Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane [...]
mrpl38 protein networkhttps://string-db.org/network/284812.O9429254S ribosomal protein L38, mitochondrial.
SPBC887.08 protein networkhttps://string-db.org/network/284812.O94293Uncharacterized protein C887.08.
sog2 protein networkhttps://string-db.org/network/284812.O94294Leucine-rich repeat-containing protein sog2.
pus2 protein networkhttps://string-db.org/network/284812.O94295tRNA pseudouridine synthase 2; Formation of pseudouridine at positions 27 and 28 in the anticodon stem and loop of transfer RNAs; at positions 34 and 36 of intron-containing precursor tRNA(Ile) a [...]
SPBC887.12 protein networkhttps://string-db.org/network/284812.O94296Probable phospholipid-transporting ATPase C887.12; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of phospholipids.
cem1 protein networkhttps://string-db.org/network/284812.O94297Putative 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial functi [...]
sur2 protein networkhttps://string-db.org/network/284812.O94298Sphingolipid C4-hydroxylase sur2; Required for hydroxylation of C-4 in the sphingoid moiety of ceramide. Involved in the response to syringomycin (By similarity).
SPBC887.16 protein networkhttps://string-db.org/network/284812.O94299Uncharacterized protein C887.16.
SPBC887.17 protein networkhttps://string-db.org/network/284812.O94300Putative xanthine/uracil permease C887.17.
hfi1 protein networkhttps://string-db.org/network/284812.O94301Transcriptional coactivator hfi1; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and SLIK. SAGA is involved in RNA polymerase II-dependent [...]
rft1 protein networkhttps://string-db.org/network/284812.O94302Oligosaccharide translocation protein rft1; May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane; Belongs to [...]
his4 protein networkhttps://string-db.org/network/284812.O94303Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclas [...]
mgl1 protein networkhttps://string-db.org/network/284812.O94305Putative monoglyceride lipase; Converts monoacylglycerides (MAG) to free fatty acids and glycerol. Required for efficient degradation of MAG, short-lived intermediates of glycerolipid metabolism [...]
rpp21 protein networkhttps://string-db.org/network/284812.O94306Uncharacterized protein C16C4.19.
pfd5 protein networkhttps://string-db.org/network/284812.O94307Probable prefoldin subunit 5; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in [...]
csn1 protein networkhttps://string-db.org/network/284812.O94308COP9 signalosome complex subunit 1; Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cull [...]
git11 protein networkhttps://string-db.org/network/284812.O94309Guanine nucleotide-binding protein subunit gamma; Belongs to the G protein gamma family.
SPBC215.06c protein networkhttps://string-db.org/network/284812.O94311UPF0743 protein C215.06c.
pdp2 protein networkhttps://string-db.org/network/284812.O94312PWWP domain-containing protein2.
arg4 protein networkhttps://string-db.org/network/284812.O94313Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family.
odr1 protein networkhttps://string-db.org/network/284812.O94314Uncharacterized hydrolase C215.10.
SPBC215.11c protein networkhttps://string-db.org/network/284812.O94315Uncharacterized oxidoreductase C215.11c.
cwf10 protein networkhttps://string-db.org/network/284812.O94316Pre-mRNA-splicing factor cwf10; Component of the U5 snRNP complex required for pre-mRNA splicing. Binds GTP; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation [...]
mtl3 protein networkhttps://string-db.org/network/284812.O94317Uncharacterized serine-rich protein C215.13.
vps20 protein networkhttps://string-db.org/network/284812.O94318Vacuolar protein sorting-associated protein 20; Class E VPS protein implicated in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal [...]
sec13 protein networkhttps://string-db.org/network/284812.O94319Protein transport protein sec13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main fun [...]
maa1 protein networkhttps://string-db.org/network/284812.O94320Aspartate aminotransferase, mitochondrial; Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol (By similarity). Belongs to the class-I py [...]
mpr1 protein networkhttps://string-db.org/network/284812.O94321Multistep phosphorelay regulator 1; Binds to the msc4 response regulator which is part of a multistep phosphorelay system that transmits oxidative stress signals to the spc1 MAPK cascade.
SPBC725.03 protein networkhttps://string-db.org/network/284812.O94322Uncharacterized protein C725.03; To yeast YGR017w.
npp1 protein networkhttps://string-db.org/network/284812.O94323Uncharacterized pyrophosphatase/phosphodiesterase C725.05c.
ppk31 protein networkhttps://string-db.org/network/284812.O94324Serine/threonine-protein kinase ppk31; Has a role in meiosis; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
pex5 protein networkhttps://string-db.org/network/284812.O94325Peroxisomal targeting signal receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
pir2 protein networkhttps://string-db.org/network/284812.O94326Zinc finger protein C725.08.
tps0 protein networkhttps://string-db.org/network/284812.O94327Translocator protein homolog; May play a role in the transport of porphyrins and heme. Belongs to the TspO/BZRP family.
nbl1 protein networkhttps://string-db.org/network/284812.O94328Meiotically up-regulated gene 118 protein; Has a role in meiosis.
psf2 protein networkhttps://string-db.org/network/284812.O94329DNA replication complex GINS protein psf2; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation and is required for bir1 localizatio [...]
arg6 protein networkhttps://string-db.org/network/284812.O94330Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family.
ura5 protein networkhttps://string-db.org/network/284812.O94331Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP); B [...]
rrn11 protein networkhttps://string-db.org/network/284812.O94332RNA polymerase I-specific transcription initiation factor rrn11; Subunit of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I. Binding to the DNA templ [...]
pof13 protein networkhttps://string-db.org/network/284812.O94334F-box protein pof13.
stt3 protein networkhttps://string-db.org/network/284812.O94335Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3; Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined gly [...]
SPBC1271.03c protein networkhttps://string-db.org/network/284812.O94336Uncharacterized FCP1 homology domain-containing protein C1271.03c.
dys1 protein networkhttps://string-db.org/network/284812.O94337Probable deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a sp [...]
SPBC1271.05c protein networkhttps://string-db.org/network/284812.O94338AN1-type zinc finger protein C1271.05c.
mug96 protein networkhttps://string-db.org/network/284812.O94339Meiotically up-regulated gene 96 protein; Has a role in meiosis.
SPBC1271.07c protein networkhttps://string-db.org/network/284812.O94340Uncharacterized N-acetyltransferase C1271.07c.
SPBC1271.08c protein networkhttps://string-db.org/network/284812.O94341Uncharacterized protein C1271.08c.
tgp1 protein networkhttps://string-db.org/network/284812.O94342Probable metabolite transport protein C1271.09.
pet802 protein networkhttps://string-db.org/network/284812.O94344Uncharacterized mitochondrial carrier C1271.11.
mrpl8 protein networkhttps://string-db.org/network/284812.O9434554S ribosomal protein L8, mitochondrial; Belongs to the bacterial ribosomal protein bL17 family.
aga1 protein networkhttps://string-db.org/network/284812.O94346Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from g [...]
nnr2 protein networkhttps://string-db.org/network/284812.O94347ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which cataly [...]
SPCC61.04c protein networkhttps://string-db.org/network/284812.O94348Protein transport protein yip1; Required for fusion of ER-derived vesicles with the Golgi during ER-to-Golgi protein transport, probably by mediating correct membrane localization of ypt1.
SPCC61.05 protein networkhttps://string-db.org/network/284812.O94349Uncharacterized membrane protein C61.05.
cbl1 protein networkhttps://string-db.org/network/284812.O94350Cystathionine beta-lyase.
apq12 protein networkhttps://string-db.org/network/284812.O94353Nuclear membrane organization protein apq12; Involved in the regulation of lipid homeostasis in the endoplasmic reticulum, thereby impacting nuclear pore complex biogenesis and localization, and [...]
arg12 protein networkhttps://string-db.org/network/284812.O94354Argininosuccinate synthase.
rxt2 protein networkhttps://string-db.org/network/284812.O94355Transcriptional regulatory protein rxt2; Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histo [...]
meu6 protein networkhttps://string-db.org/network/284812.O94356Meiotic expression up-regulated protein 6.
SPBC428.10 protein networkhttps://string-db.org/network/284812.O94358Uncharacterized protein C428.10.
SPBC428.12c protein networkhttps://string-db.org/network/284812.O94359Uncharacterized RNA-binding protein C428.12c.
mob1 protein networkhttps://string-db.org/network/284812.O94360Maintenance of ploidy protein mob1; Has a role in promoting the onset of septum formation during the latter stages of mitosis; Belongs to the MOB1/phocein family.
SPBC428.14 protein networkhttps://string-db.org/network/284812.O94361Uncharacterized acyltransferase C428.14.
SPBC428.15 protein networkhttps://string-db.org/network/284812.O94362Uncharacterized GTP-binding protein C428.15.
rhb1 protein networkhttps://string-db.org/network/284812.O94363GTP-binding protein rhb1; Regulates entry into stationary phase when extracellular nitrogen levels are adequate for growth; Belongs to the small GTPase superfamily. Rheb family.
wpl1 protein networkhttps://string-db.org/network/284812.O94364Wings apart-like protein homolog 1; Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Belongs to the WAPL family.
utp15 protein networkhttps://string-db.org/network/284812.O94365U3 small nucleolar RNA-associated protein 15; Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a s [...]
ppr1 protein networkhttps://string-db.org/network/284812.O94368Pentatricopeptide repeat-containing protein 1, mitochondrial; Mitochondrial RNA-binding protein required for the stability of the cox2 and cox3 mRNAs.
SPBC1604.04 protein networkhttps://string-db.org/network/284812.O94370Uncharacterized mitochondrial carrier C1604.04.
noc4 protein networkhttps://string-db.org/network/284812.O94372Uncharacterized protein C1604.06c.
atp4 protein networkhttps://string-db.org/network/284812.O94373ATP synthase subunit 4, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
imp1 protein networkhttps://string-db.org/network/284812.O94374Importin subunit alpha-2; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural com [...]
rex4 protein networkhttps://string-db.org/network/284812.O94375RNA exonuclease 4; Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs (By similarity); [...]
srb7 protein networkhttps://string-db.org/network/284812.O94376Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
atp17 protein networkhttps://string-db.org/network/284812.O94377ATP synthase subunit f, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
SPBC1604.12 protein networkhttps://string-db.org/network/284812.O94378Uncharacterized protein C1604.12.
mrpl32 protein networkhttps://string-db.org/network/284812.O94379Probable 54S ribosomal protein L32, mitochondrial; Component of the large subunit of mitochondrial ribosome. Belongs to the bacterial ribosomal protein bL32 family.
gpi16 protein networkhttps://string-db.org/network/284812.O94380GPI transamidase component PIG-T homolog; Component of the GPI transamidase complex. Involved in transfer of GPI to proteins (By similarity).
psm1 protein networkhttps://string-db.org/network/284812.O94383Structural maintenance of chromosomes protein 1; Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the [...]
ely5 protein networkhttps://string-db.org/network/284812.O94384Uncharacterized protein ely5.
pom152 protein networkhttps://string-db.org/network/284812.O94385Nucleoporin pom152; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural component [...]
tri1 protein networkhttps://string-db.org/network/284812.O94386Uncharacterized protein C29A10.09c; Belongs to the CAF1 family.
dbl8 protein networkhttps://string-db.org/network/284812.O94387Uncharacterized ATP-dependent helicase C29A10.10c.
muk1 protein networkhttps://string-db.org/network/284812.O94388Vacuolar protein sorting-associated protein 9b.
oxs1 protein networkhttps://string-db.org/network/284812.O94389Coiled-coil domain-containing protein 124 homolog.
atp7 protein networkhttps://string-db.org/network/284812.O94390ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
cyb502 protein networkhttps://string-db.org/network/284812.O94391Probable cytochrome b5 1; Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases; Belongs to the cytochrome b5 family.
SPAC2H10.01 protein networkhttps://string-db.org/network/284812.O94392Uncharacterized transcriptional regulatory protein C2H10.01.
nas2 protein networkhttps://string-db.org/network/284812.O94393Probable 26S proteasome regulatory subunit p27; Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC).
SPCC126.01c protein networkhttps://string-db.org/network/284812.O94394Uncharacterized WD repeat-containing protein C126.01c.
pku70 protein networkhttps://string-db.org/network/284812.O94395ATP-dependent DNA helicase II subunit 1; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequenc [...]
pus1 protein networkhttps://string-db.org/network/284812.O94396tRNA pseudouridine synthase 1; Formation of pseudouridine at positions 27 and 28 in the anticodon stem and loop of transfer RNAs; at positions 34 and 36 of intron-containing precursor tRNA(Ile) a [...]
sgf73 protein networkhttps://string-db.org/network/284812.O94397SAGA-associated factor 73; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcrip [...]
mrpl17 protein networkhttps://string-db.org/network/284812.O9439854S ribosomal protein L17, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL46 family.
twf1 protein networkhttps://string-db.org/network/284812.O94399Twinfilin; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. Prevents actin filament assembly by forming a 1:1 [...]
asr1 protein networkhttps://string-db.org/network/284812.O94400PHD and RING finger domain-containing protein C126.07c.
SPCC126.08c protein networkhttps://string-db.org/network/284812.O94401L-type lectin-like domain-containing protein C126.08c.
zip2 protein networkhttps://string-db.org/network/284812.O94402Probable zinc transporter zip2; Probable zinc transporter that may mediate zinc remobilization from the endoplasmic reticulum under zinc limitation. Belongs to the ZIP transporter (TC 2.A.5) fami [...]
SPCC126.11c protein networkhttps://string-db.org/network/284812.O94403Uncharacterized RNA-binding protein C126.11c.
SPCC126.12 protein networkhttps://string-db.org/network/284812.O94404Protein NIF3 homolog; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
sap18 protein networkhttps://string-db.org/network/284812.O94405Uncharacterized protein C126.13c.
prp18 protein networkhttps://string-db.org/network/284812.O94406Pre-mRNA-splicing factor 18; Participates in the second step of pre-mRNA splicing. Belongs to the PRP18 family.
sec65 protein networkhttps://string-db.org/network/284812.O94407Signal recognition particle sec65 subunit; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. It must be involved [...]
lsm2 protein networkhttps://string-db.org/network/284812.O94408U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
wtf23 protein networkhttps://string-db.org/network/284812.O94409Uncharacterized protein wtf23.
mug163 protein networkhttps://string-db.org/network/284812.O94410Meiotically up-regulated gene 163 protein; Has a role in meiosis.
fzr3 protein networkhttps://string-db.org/network/284812.O94411Meiotic fizzy-related protein 2; Has a role in meiosis; Belongs to the WD repeat CDC20/Fizzy family.
bet4 protein networkhttps://string-db.org/network/284812.O94412Geranylgeranyl transferase type-2 subunit alpha; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to proteins having the C-terminal-XCC or -XCXC, where both c [...]
SPCC1620.06c protein networkhttps://string-db.org/network/284812.O94413Ribose-phosphate pyrophosphokinase 2; 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phos [...]
lnp1 protein networkhttps://string-db.org/network/284812.O94414Endoplasmic reticulum junction formation protein lunapark; Plays a role in tubular endoplasmic reticulum network formation and maintenance; Belongs to the lunapark family.
lsc2 protein networkhttps://string-db.org/network/284812.O94415Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP [...]
tfg1 protein networkhttps://string-db.org/network/284812.O94416Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collabor [...]
cwf26 protein networkhttps://string-db.org/network/284812.O94417Pre-mRNA-splicing factor cwf26; Involved in mRNA splicing.
nup97 protein networkhttps://string-db.org/network/284812.O94418Meiotically up-regulated gene 87 protein; Has a role in meiosis; Belongs to the nucleoporin interacting component (NIC) family.
SPCC1620.12c protein networkhttps://string-db.org/network/284812.O94419Putative GTPase-activating protein C1620.12c.
SPCC1620.13 protein networkhttps://string-db.org/network/284812.O94420Probable phosphatase C1620.13.
snf22 protein networkhttps://string-db.org/network/284812.O94421SWI/SNF chromatin-remodeling complex subunit snf22; Helicase. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of [...]
mfr1 protein networkhttps://string-db.org/network/284812.O94423Meiotic fizzy-related protein 1; Meiosis-specific activator of the anaphase promoting complex/cyclosome (APC/C). Involved in cdc13 degradation.
tfg2 protein networkhttps://string-db.org/network/284812.O94424Transcription initiation factor IIF subunit beta; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collabora [...]
wwm3 protein networkhttps://string-db.org/network/284812.O94425WW domain-containing protein C660.05.
wwm2 protein networkhttps://string-db.org/network/284812.O94426WW domain-containing protein C660.06.
atg38 protein networkhttps://string-db.org/network/284812.O94427Meiotically up-regulated gene 167 protein; Has a role in meiosis.
mug168 protein networkhttps://string-db.org/network/284812.O94428Meiotically up-regulated gene 168 protein; Has a role in meiosis.
mef2 protein networkhttps://string-db.org/network/284812.O94429Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involv [...]
egt2 protein networkhttps://string-db.org/network/284812.O94431Hercynylcysteine sulfoxide lyase; Catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine by cleaving the cysteine residue at the sulfur atom, the last step in the biosynthesis pa [...]
msi2 protein networkhttps://string-db.org/network/284812.O94432Uncharacterized RNA-binding protein C660.15.
SPBC660.17c protein networkhttps://string-db.org/network/284812.O94433Uncharacterized membrane protein C660.17c.
mug35 protein networkhttps://string-db.org/network/284812.O94435Meiotically up-regulated gene 35 protein; Has a role in meiosis.
tfg3 protein networkhttps://string-db.org/network/284812.O94436Transcription initiation factor TFIID subunit 14; Functions as a component of the DNA-binding general transcription factor complex TFIID, and the RNA polymerase II associated general transcriptio [...]
SPAC22H12.03 protein networkhttps://string-db.org/network/284812.O94437Abhydrolase domain-containing protein C22H12.03.
rps102 protein networkhttps://string-db.org/network/284812.O9443840S ribosomal protein S1-B.
fsc1 protein networkhttps://string-db.org/network/284812.O94439FAS1 domain-containing protein fsc1; Required for the fusion of autophagosomes with the vacuole.
SPAC637.03 protein networkhttps://string-db.org/network/284812.O94440Uncharacterized protein C637.03.
ypp1 protein networkhttps://string-db.org/network/284812.O94441Putative cargo-transport protein ypp1; Involved in endocytosis; Belongs to the YPP1 family.
nbp35 protein networkhttps://string-db.org/network/284812.O94442Cytosolic Fe-S cluster assembly factor nbp35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nbp3 [...]
rex1 protein networkhttps://string-db.org/network/284812.O94443Uncharacterized exonuclease C637.09.
rpn10 protein networkhttps://string-db.org/network/284812.O9444426S proteasome regulatory subunit rpn10; Protects ubiquitin chains against dissambly by deubiquitinating enzymes thereby promoting protein degradation.
rpm2 protein networkhttps://string-db.org/network/284812.O94445ATP-dependent RNA helicase suv3, mitochondrial; Required for intron-independent turnover and processing of mitochondrial RNA. It is a key control element in nuclear-mitochondrial interactions (By [...]
mst1 protein networkhttps://string-db.org/network/284812.O94446Histone acetyltransferase mst1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by [...]
slm1 protein networkhttps://string-db.org/network/284812.O94447Cytoskeletal signaling protein slm1; Effector of the TORC2- and calcineurin-signaling pathways. Mediates actin polarization via inhibition of calcineurin-dependent transcription (By similarity).
rce1 protein networkhttps://string-db.org/network/284812.O94448Probable CAAX prenyl protease 2; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase U48 family.
rfc4 protein networkhttps://string-db.org/network/284812.O94449Replication factor C subunit 4; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1.
mcb1 protein networkhttps://string-db.org/network/284812.O94450UPF0616 protein C1687.04; Belongs to the UPF0616 family.
pli1 protein networkhttps://string-db.org/network/284812.O94451E3 SUMO-protein ligase pli1; Acts as an E3 ligase mediating SUMO/Smt3 attachment to other proteins. Involved in the maintenance of the centromere and in telomere length. Regulates recombination, [...]
mcp1 protein networkhttps://string-db.org/network/284812.O94452Meiotic coiled-coil protein 1.
coq4 protein networkhttps://string-db.org/network/284812.O94453Ubiquinone biosynthesis protein coq4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q bio [...]
csn5 protein networkhttps://string-db.org/network/284812.O94454COP9 signalosome complex subunit 5; Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation o [...]
SPAC1687.14c protein networkhttps://string-db.org/network/284812.O94455Uncharacterized calcium-binding protein C1687.14c.
erg31 protein networkhttps://string-db.org/network/284812.O94457Delta(7)-sterol 5(6)-desaturase erg31; Catalyzes the introduction of a C-5 double bond in the B ring of ergosterol. Involved in the biosynthesis or ergosterol which is important for plasma membra [...]
SPAC1687.17c protein networkhttps://string-db.org/network/284812.O94458Uncharacterized derlin-like protein C1687.17c.
ssl3 protein networkhttps://string-db.org/network/284812.O94459MAU2 chromatid cohesion factor homolog; Involved in sister chromatid cohesion. Forms a complex with mis4, which is required for the association of the cohesin complex with chromosomes.
qtr1 protein networkhttps://string-db.org/network/284812.O94460Queuine tRNA-ribosyltransferase catalytic subunit; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at pos [...]
SPAC1687.21 protein networkhttps://string-db.org/network/284812.O94461Probable phosphatase C1687.21.
puf3 protein networkhttps://string-db.org/network/284812.O94462mRNA-binding protein puf3; RNA-binding protein involved in post-transcriptional regulation. Predominantly binds to mRNAs encoding mitochondrial proteins and localizes them to the vicinity of mito [...]
nvj2 protein networkhttps://string-db.org/network/284812.O94464Uncharacterized protein C23G7.06c.
cms1 protein networkhttps://string-db.org/network/284812.O94465Protein cms1; May play a role in the regulation of DNA replication and cell cycle control; Belongs to the CMS1 family.
rga7 protein networkhttps://string-db.org/network/284812.O94466Probable Rho-GTPase-activating protein 7.
SPBC23G7.10c protein networkhttps://string-db.org/network/284812.O94467Putative NADPH dehydrogenase C23G7.10c.
mag2 protein networkhttps://string-db.org/network/284812.O94468Probable DNA-3-methyladenine glycosylase 2; Involved in base excision repair of methyl methanesulfonate- damaged DNA by hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine o [...]
SPBC23G7.13c protein networkhttps://string-db.org/network/284812.O94469Probable urea active transporter 1; Involved in active transport of urea; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
SPBC23G7.14 protein networkhttps://string-db.org/network/284812.O94470Uncharacterized protein C23G7.14.
pbn1 protein networkhttps://string-db.org/network/284812.O94472Protein pbn1; Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfer [...]
SPCC1919.04 protein networkhttps://string-db.org/network/284812.O94473Uncharacterized membrane protein C1919.04.
ski3 protein networkhttps://string-db.org/network/284812.O94474Superkiller protein 3; Component of the SKI complex involved in 3'-mRNA degradation pathway.
tif6 protein networkhttps://string-db.org/network/284812.O94476Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is [...]
myo52 protein networkhttps://string-db.org/network/284812.O94477Myosin-52; Involved in cell wall deposition where it has a role in the localization of mok1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
mug137 protein networkhttps://string-db.org/network/284812.O94478Meiotically up-regulated gene 137 protein; Has a role in meiosis and sporulation.
bmt5 protein networkhttps://string-db.org/network/284812.O9448025S rRNA (uridine-N(3))-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(3) position of a uridine in 25S rRNA.
bdp1 protein networkhttps://string-db.org/network/284812.O94481Transcription factor TFIIIB component B'; General activator of RNA polymerase III transcription.
dad5 protein networkhttps://string-db.org/network/284812.O94483High osmolarity sensitivity protein 3; May play a role in the progression of mitosis in an environment of high osmotic stress.
cfh2 protein networkhttps://string-db.org/network/284812.O94486Chitin synthase regulatory factor 2; Involved in chitin biosynthesis.
mug27 protein networkhttps://string-db.org/network/284812.O94487Serine/threonine-protein kinase ppk35; Has a role in meiosis; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
mto1 protein networkhttps://string-db.org/network/284812.O94488Microtubule organizer protein 1; Required for cytoplasmic astral microtubule growth during mitosis. Involved in localizing components of the gamma-tubulin complex to the non-spindle pole body (no [...]
tef3 protein networkhttps://string-db.org/network/284812.O94489Elongation factor 3; The main role of EF-3 may be to transduce nucleoside triphosphate energy into mechanical energy for translocation during translation. EF-3 stimulates EF-1-alpha-dependent bin [...]
SPCC417.09c protein networkhttps://string-db.org/network/284812.O94490Uncharacterized transcriptional regulatory protein C417.09c.
dal51 protein networkhttps://string-db.org/network/284812.O94491Uncharacterized transporter C417.10.
SPCC417.11c protein networkhttps://string-db.org/network/284812.O94492Uncharacterized aminotransferase C417.11c; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
SPCC417.12 protein networkhttps://string-db.org/network/284812.O94493Uncharacterized esterase/lipase C417.12.
sim4 protein networkhttps://string-db.org/network/284812.O94494Inner kinetochore subunit sim4; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segre [...]
elp5 protein networkhttps://string-db.org/network/284812.O94495Elongator complex protein 5; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in trans [...]
aim21 protein networkhttps://string-db.org/network/284812.O94497Uncharacterized serine-rich protein C18E5.07.
SPBC18E5.08 protein networkhttps://string-db.org/network/284812.O94498Uncharacterized N-acetyltransferase C18E5.08.
SPBC18E5.10 protein networkhttps://string-db.org/network/284812.O94500NADH-ubiquinone oxidoreductase 51 kDa subunit homolog SPBC18E5.10, mitochondrial.
cct1 protein networkhttps://string-db.org/network/284812.O94501T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
SPBC12D12.05c protein networkhttps://string-db.org/network/284812.O94502Uncharacterized mitochondrial carrier C12D12.05c.
srb11 protein networkhttps://string-db.org/network/284812.O94503RNA polymerase II holoenzyme cyclin-like subunit; Component of the Cdk8 module/Srb8-11 module which is a regulatory module of the Mediator complex that regulates basal RNA polymerase II transcrip [...]
trx2 protein networkhttps://string-db.org/network/284812.O94504Thioredoxin-2, mitochondrial; Disulfide reductase which serves multiple functions in mitochondria, protecting mitochondrial components against thiol- oxidative damage as a thiol-disulfide oxidore [...]
tol1 protein networkhttps://string-db.org/network/284812.O945053'(2'),5'-bisphosphate nucleotidase; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Regulate [...]
rsm1 protein networkhttps://string-db.org/network/284812.O94506mRNA export factor rsm1; Involved in the export of mRNA from the nucleus to the cytoplasm.
cwf11 protein networkhttps://string-db.org/network/284812.O94508Pre-mRNA-splicing factor cwf11; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome; Belongs to the CWF11 family.
gta1 protein networkhttps://string-db.org/network/284812.O94509Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. [...]
agn2 protein networkhttps://string-db.org/network/284812.O94510Glucan endo-1,3-alpha-glucosidase agn2; Involved in the endolysis of the ascus wall.
tsc13 protein networkhttps://string-db.org/network/284812.O94511Putative enoyl reductase C646.07c; Belongs to the steroid 5-alpha reductase family.
oss1 protein networkhttps://string-db.org/network/284812.O94512Oxysterol-binding protein-like protein 1.
int6 protein networkhttps://string-db.org/network/284812.O94513Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoi [...]
nop56 protein networkhttps://string-db.org/network/284812.O94514Nucleolar protein 56; Required for 60S ribosomal subunit synthesis.
cct6 protein networkhttps://string-db.org/network/284812.O94515T-complex protein 1 subunit zeta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
pex16 protein networkhttps://string-db.org/network/284812.O94516Peroxisomal membrane protein PEX16; Involved in the biogenesis of peroxisomes; Belongs to the peroxin-16 family.
scl1 protein networkhttps://string-db.org/network/284812.O94517Probable proteasome subunit alpha type-1; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent [...]
dic1 protein networkhttps://string-db.org/network/284812.O94518Dynein intermediate chain 1; Has a role in meiotic nuclear divsion where it promotes the movement of 'horsetails'; Belongs to the dynein intermediate chain family.
spf30 protein networkhttps://string-db.org/network/284812.O94519Splicing factor spf30; Necessary for spliceosome assembly.
emc4 protein networkhttps://string-db.org/network/284812.O94520ER membrane protein complex subunit 4.
akr7 protein networkhttps://string-db.org/network/284812.O94521Probable pyridoxal reductase 2; Catalyzes the reduction of pyridoxal (PL) with NADPH and oxidation of pyridoxine (PN) with NADP(+).
rsc7 protein networkhttps://string-db.org/network/284812.O94522Chromatin structure-remodeling complex subunit rsc7; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Contr [...]
ole1 protein networkhttps://string-db.org/network/284812.O94523Probable acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catal [...]
gst4 protein networkhttps://string-db.org/network/284812.O94524Glutathione S-transferase omega-like 2; Active as '1-Cys' thiol transferase against beta-hydroxyethyl disulfide (HED), as dehydroascorbate reductase and as dimethylarsinic acid reductase, while n [...]
SPBC609.01 protein networkhttps://string-db.org/network/284812.O94525Uncharacterized ribonuclease C609.01.
ptn1 protein networkhttps://string-db.org/network/284812.O94526Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase ptn1; Acts as a phosphoinositide 3-phosphatase and regulates PtdIns(3,4,5)P3 levels.
iqw1 protein networkhttps://string-db.org/network/284812.O94527WD repeat protein iqw1; Ligand-dependent coactivator of nuclear receptors that may function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
caf5 protein networkhttps://string-db.org/network/284812.O94528Caffeine resistance protein 5.
pob3 protein networkhttps://string-db.org/network/284812.O94529FACT complex subunit pob3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a [...]
sua5 protein networkhttps://string-db.org/network/284812.O94530Threonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Likely catalyzes th [...]
ufe1 protein networkhttps://string-db.org/network/284812.O94531Syntaxin ufe1; Syntaxin required for targeting and fusion of Golgi-derived retrograde transport vesicles with the ER; Belongs to the syntaxin family.
for3 protein networkhttps://string-db.org/network/284812.O94532Formin-3; Involved in controlling polarized cell growth. Required for interphase actin cable formation and microtubule organization. Belongs to the formin homology family.
elp2 protein networkhttps://string-db.org/network/284812.O94533Elongator complex protein 2; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in trans [...]
alp14 protein networkhttps://string-db.org/network/284812.O94534Spindle pole body component alp14; Required for bipolar spindle formation and proper chromosome segregation. Has a role in connecting the kinetochores and the plus end of pole to chromosome micro [...]
ucp12 protein networkhttps://string-db.org/network/284812.O94536Putative ATP-dependent RNA helicase ucp12; Probable ATP-binding RNA helicase.
ire1 protein networkhttps://string-db.org/network/284812.O94537Serine/threonine-protein kinase ppk4.
snu66 protein networkhttps://string-db.org/network/284812.O94538U4/U6.U5 tri-snRNP-associated protein snu66; Required for efficient splicing of pre-mRNA. Belongs to the SNU66/SART1 family.
pam17 protein networkhttps://string-db.org/network/284812.O94539Presequence translocated-associated motor subunit pam17, mitochondrial; Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inne [...]
pxd1 protein networkhttps://string-db.org/network/284812.O94542Uncharacterized protein C1322.02.
trp1322 protein networkhttps://string-db.org/network/284812.O94543Uncharacterized membrane protein C1322.03.
lap2 protein networkhttps://string-db.org/network/284812.O94544Leucine aminopeptidase 2; Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it f [...]
kap113 protein networkhttps://string-db.org/network/284812.O94545Importin beta-like protein kap113; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC struc [...]
srk1 protein networkhttps://string-db.org/network/284812.O94547Serine/threonine-protein kinase srk1; Has a role in the regulation of meiosis via the sty1 stress- activated MAPK pathway. Inhibits nitrogen-limitation induced arrest at G1; Belongs to the protei [...]
SPCC1322.09 protein networkhttps://string-db.org/network/284812.O94548Maintenance of telomere capping protein 1; Involved in telomere capping; Belongs to the MTC1 family.
phb2 protein networkhttps://string-db.org/network/284812.O94550Prohibitin-2; Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins.
fum1 protein networkhttps://string-db.org/network/284812.O94552Fumarate hydratase, mitochondrial; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. In mitochondrion, catalyzes the hydration of fumarate to L-malate in the tricar [...]
rpc34 protein networkhttps://string-db.org/network/284812.O94553Probable DNA-directed RNA polymerase III subunit rpc6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific [...]
cut23 protein networkhttps://string-db.org/network/284812.O94556Anaphase-promoting complex subunit 8; Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through m [...]
les1 protein networkhttps://string-db.org/network/284812.O94559Uncharacterized protein C23C4.05c; Belongs to the LEA type 1 family.
far8 protein networkhttps://string-db.org/network/284812.O94560Uncharacterized WD repeat-containing protein C1773.01.
bcp1 protein networkhttps://string-db.org/network/284812.O94561Peroxiredoxin bcp1; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection aga [...]
SPBC1773.03c protein networkhttps://string-db.org/network/284812.O94562Uncharacterized aminotransferase C1771.03c.
SPBC1773.04 protein networkhttps://string-db.org/network/284812.O94563Putative uncharacterized oxidoreductase C1773.04; Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
adh8 protein networkhttps://string-db.org/network/284812.O94564Zinc-type alcohol dehydrogenase-like protein C1773.06c.
mug184 protein networkhttps://string-db.org/network/284812.O94566Meiotically up-regulated gene 184 protein; Has a role in sporulation.
nrs1 protein networkhttps://string-db.org/network/284812.O94567Probable asparagine--tRNA ligase, cytoplasmic; Cytosolic asparaginyl-tRNA synthetase which catalyzes the specific attachment of asparagine to its cognate tRNA.
SPBC1773.12 protein networkhttps://string-db.org/network/284812.O94569Uncharacterized transcriptional regulatory protein C1773.12.
SPBC1773.13 protein networkhttps://string-db.org/network/284812.O94570Aromatic amino acid aminotransferase C1773.13; Has aromatic amino acid transaminase activity. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
gor2 protein networkhttps://string-db.org/network/284812.O94574Putative 2-hydroxyacid dehydrogenase C1773.17c; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
SPCC1442.04c protein networkhttps://string-db.org/network/284812.O94577Reduced meiotic recombination protein C1442.04c; Required for normal levels of gene conversion events during meiosis; Belongs to the RMR1 family.
mic26 protein networkhttps://string-db.org/network/284812.O94578Uncharacterized protein C1442.05c.
pre8 protein networkhttps://string-db.org/network/284812.O94579Probable proteasome subunit alpha type-2; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent [...]
wss2 protein networkhttps://string-db.org/network/284812.O94580Ubiquitin and WLM domain-containing metalloprotease SPCC1442.07c.
cox12 protein networkhttps://string-db.org/network/284812.O94581Cytochrome c oxidase subunit 12, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The re [...]
trp3 protein networkhttps://string-db.org/network/284812.O94582Probable anthranilate synthase component 1.
pps1 protein networkhttps://string-db.org/network/284812.O94584CDP-diacylglycerol--serine O-phosphatidyltransferase; Phosphatidylserine synthase involved in the regulation of processes such as cell morphology, cytokinesis, actin cytoskeleton, and cell wall r [...]
sqs2 protein networkhttps://string-db.org/network/284812.O94585Meiotically up-regulated protein C1442.13c; Has a role in meiosis and sporulation. Required for meiotic chromosome segregation.
hnt1 protein networkhttps://string-db.org/network/284812.O94586Hit family protein 1; Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2.
cox18 protein networkhttps://string-db.org/network/284812.O94587Cytochrome c oxidase assembly protein cox18, mitochondrial; Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly [...]
cuf2 protein networkhttps://string-db.org/network/284812.O94588Copper-binding regulatory protein cuf2.
SPCC584.03c protein networkhttps://string-db.org/network/284812.O94589RanBD1 domain-containing protein C584.03c.
sec1 protein networkhttps://string-db.org/network/284812.O94590Protein transport protein sec1; Involved in the final stage of protein secretion. Belongs to the STXBP/unc-18/SEC1 family.
sec5 protein networkhttps://string-db.org/network/284812.O94598Exocyst complex component sec5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
lmb1 protein networkhttps://string-db.org/network/284812.O94599LIMR family protein C622.11.
tti1 protein networkhttps://string-db.org/network/284812.O94600TEL2-interacting protein 1; Component of the TORC1 and TORC2 complexes required for the regulation of the cellular respons to changes in available nutrients.
SPCC622.14 protein networkhttps://string-db.org/network/284812.O94601Uncharacterized protein C622.14; GTPase-activating protein for the ADP ribosylation factor family.
epe1 protein networkhttps://string-db.org/network/284812.O94603Putative JmjC domain-containing histone demethylation protein 1; May be a histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code [...]
jmj4 protein networkhttps://string-db.org/network/284812.O94606JmjC domain-containing protein 4; Has a role in meiosis.
str2 protein networkhttps://string-db.org/network/284812.O94607Siderophore iron transporter 2; Involved in the transport of siderophore iron and so has a role in iron homeostasis; Belongs to the major facilitator superfamily.
ptr3 protein networkhttps://string-db.org/network/284812.O94609Ubiquitin-activating enzyme E1 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first [...]
mug65 protein networkhttps://string-db.org/network/284812.O94611Meiotically up-regulated gene 65 protein; Has a role in meiosis.
lcp1 protein networkhttps://string-db.org/network/284812.O94612Uncharacterized cyclin-L1-like protein C1296.05c.
tah18 protein networkhttps://string-db.org/network/284812.O94613NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of [...]
chr4 protein networkhttps://string-db.org/network/284812.O94614Chitin synthase regulatory factor 4; Involved in septum formation. Required for the proper localization of chs2 at the septum.
ppr8 protein networkhttps://string-db.org/network/284812.O94615Pentatricopeptide repeat-containing protein 8, mitochondrial; Mitochondrial RNA-binding protein involved in mitochondrial translation. The cox1 mRNA is one target but it is not clear if ppr8 has [...]
rpc40 protein networkhttps://string-db.org/network/284812.O94616DNA-directed RNA polymerases I and III subunit RPAC1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common co [...]
uap1 protein networkhttps://string-db.org/network/284812.O94617Probable UDP-N-acetylglucosamine pyrophosphorylase.
tim21 protein networkhttps://string-db.org/network/284812.O94618Mitochondrial import inner membrane translocase subunit tim21; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across th [...]
adn2 protein networkhttps://string-db.org/network/284812.O94619Adhesion defective protein 2; Probable transcriptional regulator involved in cell adhesion. Belongs to the FLO8 family.
spf38 protein networkhttps://string-db.org/network/284812.O94620Pre-mRNA-splicing factor cwf17; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
usp109 protein networkhttps://string-db.org/network/284812.O94621U1 snRNP-associated protein usp109.
gmh6 protein networkhttps://string-db.org/network/284812.O94622Uncharacterized alpha-1,2-galactosyltransferase C1289.13c.
rev1 protein networkhttps://string-db.org/network/284812.O94623DNA repair protein rev1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the fir [...]
tim54 protein networkhttps://string-db.org/network/284812.O94624Mitochondrial import inner membrane translocase subunit tim54; Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into [...]
scj1 protein networkhttps://string-db.org/network/284812.O94625DnaJ-related protein spj1.
rex2 protein networkhttps://string-db.org/network/284812.O94626Probable oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
rnh202 protein networkhttps://string-db.org/network/284812.O94627Ribonuclease H2 subunit B; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the rem [...]
SPBC1347.09 protein networkhttps://string-db.org/network/284812.O94628Uncharacterized methyltransferase C1347.09; Probable methyltransferase; Belongs to the methyltransferase superfamily.
sro1 protein networkhttps://string-db.org/network/284812.O94629Stress-responsive protein 1; Stress-responsive protein that may play a role in regulation of cell cycle.
arp1 protein networkhttps://string-db.org/network/284812.O94630Centractin; Core component of the dynactin complex which assists cytoplasmic dynein by increasing its processivity and by regulation of its cargo binding. The dynactin complex is required for the [...]
mrm1 protein networkhttps://string-db.org/network/284812.O94631rRNA methyltransferase 1, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of the 2'-O- methylguanosine corresponding to position 2270 i [...]
egt1 protein networkhttps://string-db.org/network/284812.O94632L-histidine N(alpha)-methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine and subsequent conjugation with cysteine and oxygen [...]
dpm3 protein networkhttps://string-db.org/network/284812.O94633Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate-mannose synthase complex.
tda1 protein networkhttps://string-db.org/network/284812.O94634Threonine dehydratase, mitochondrial; Belongs to the serine/threonine dehydratase family.
trm11 protein networkhttps://string-db.org/network/284812.O94636tRNA (guanine(10)-N2)-methyltransferase; Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at posi [...]
kae1 protein networkhttps://string-db.org/network/284812.O94637tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs t [...]
zrt1 protein networkhttps://string-db.org/network/284812.O94639Zinc-regulated transporter 1; High-affinity zinc transport protein. Regulates intracellular zinc levels; Belongs to the ZIP transporter (TC 2.A.5) family.
sir2 protein networkhttps://string-db.org/network/284812.O94640NAD-dependent histone deacetylase sir2; Involved in silencing within the mating-type region, at the telomeres, and according to also within centromeric DNA regions. Required for the localization [...]
hsp104 protein networkhttps://string-db.org/network/284812.O94641Heat shock protein 104; Required, in concert with Hsp40 and Hsp70 and small Hsps, for the dissociation, resolubilization and refolding of aggregates of damaged proteins after heat or other enviro [...]
tad2 protein networkhttps://string-db.org/network/284812.O94642tRNA-specific adenosine deaminase subunit tad2; Deaminates adenosine-34 to inosine in many tRNAs. Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.
mis17 protein networkhttps://string-db.org/network/284812.O94643Inner kinetochore subunit mis17; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segr [...]
rtc5 protein networkhttps://string-db.org/network/284812.O94644Restriction of telomere capping protein 5; May be involved in a process influencing telomere capping. Belongs to the RTC5 family.
SPBC21.03c protein networkhttps://string-db.org/network/284812.O94645Uncharacterized protein C21.03c.
med8 protein networkhttps://string-db.org/network/284812.O94646Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Me [...]
ppk24 protein networkhttps://string-db.org/network/284812.O94647Serine/threonine-protein kinase ppk24, mitochondrial; Has a role late in meiosis; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
atg2 protein networkhttps://string-db.org/network/284812.O94649Autophagy-related protein 2; Required for cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes completion and peroxisome degradation (By similarity). Appears to have a role in sporula [...]
hub1 protein networkhttps://string-db.org/network/284812.O94650Ubiquitin-like modifier hub1; Forms a conjugate with snu66 and facilitates its localization to the nucleus. Involved in morphogenesis. Required for efficient splicing of pre-mRNA.
pep12 protein networkhttps://string-db.org/network/284812.O94651Syntaxin pep12; Has a role in vesicle-mediated transport but not with protein transport from Golgi to vesicle; Belongs to the syntaxin family.
gle1 protein networkhttps://string-db.org/network/284812.O94652Nucleoporin gle1; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components [...]
bms1 protein networkhttps://string-db.org/network/284812.O94653Ribosome biogenesis protein bms1; May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus; Belongs to the TRAFAC class translation factor GTPase superfamily. [...]
SPBC405.03c protein networkhttps://string-db.org/network/284812.O94654Uncharacterized transporter C405.03c.
ypt7 protein networkhttps://string-db.org/network/284812.O94655GTP-binding protein ypt7; Needed for homotypic vacuole fusion, the last step in the vacuole inheritance process; Belongs to the small GTPase superfamily. Rab family.
atg16 protein networkhttps://string-db.org/network/284812.O94656Autophagy protein 16; Stabilizes the atg5-atg12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The atg5-atg12/atg16 complex is required for efficie [...]
xdj1 protein networkhttps://string-db.org/network/284812.O94657DnaJ protein homolog xdj1.
rpl3602 protein networkhttps://string-db.org/network/284812.O9465860S ribosomal protein L36-B.
nog1 protein networkhttps://string-db.org/network/284812.O94659Probable nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
nit1 protein networkhttps://string-db.org/network/284812.O94660Probable hydrolase nit2.
gyp10 protein networkhttps://string-db.org/network/284812.O94661GTPase-activating protein gyp10; Has a role in vesicular trafficking and septation during cytokinesis.
dot2 protein networkhttps://string-db.org/network/284812.O94663Vacuolar-sorting protein dot2; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal [...]
mug166 protein networkhttps://string-db.org/network/284812.O94664Meiotically up-regulated gene 166 protein; Has a role in meiosis.
rpc1 protein networkhttps://string-db.org/network/284812.O94666DNA-directed RNA polymerase III subunit rpc1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catal [...]
prf1 protein networkhttps://string-db.org/network/284812.O94667RNA polymerase-associated protein C651.09c; The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA-binding proteins. Involved in el [...]
nse5 protein networkhttps://string-db.org/network/284812.O94668Non-structural maintenance of chromosome element 5; Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of i [...]
apm3 protein networkhttps://string-db.org/network/284812.O94669AP-3 complex subunit mu; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structur [...]
dbl7 protein networkhttps://string-db.org/network/284812.O94670Uncharacterized protein C651.12c.
hom6 protein networkhttps://string-db.org/network/284812.O94671Probable homoserine dehydrogenase; Belongs to the homoserine dehydrogenase family.
sec2302 protein networkhttps://string-db.org/network/284812.O94672Protein transport protein sec23-2; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main f [...]
gpc1 protein networkhttps://string-db.org/network/284812.O94673Glycerophosphocholine acyltransferase 1; Glycerophosphocholine acyltransferase (GPCAT) that utilizes acyl-CoA to acylate glycero-3-phosphocholine (GPC), forming lysophosphatidylcholine (LPC) (By [...]
SPBC776.06c protein networkhttps://string-db.org/network/284812.O94674AFI1-like protein C776.06c; Involved in polarity establishment; Belongs to the AFI1/mesA family.
mam33 protein networkhttps://string-db.org/network/284812.O94675Mitochondrial acidic protein mam33.
utp22 protein networkhttps://string-db.org/network/284812.O94676U3 small nucleolar RNA-associated protein 22; Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
cog6 protein networkhttps://string-db.org/network/284812.O94677Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and re [...]
cnd1 protein networkhttps://string-db.org/network/284812.O94679Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex p [...]
plh1 protein networkhttps://string-db.org/network/284812.O94680Phospholipid:diacylglycerol acyltransferase; Triacylglycerol formation by an acyl-CoA independent pathway. The enzyme specifically transfers acyl groups from the sn-2 position of a phospholipid t [...]
kgd2 protein networkhttps://string-db.org/network/284812.O946812-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase); The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and C [...]
mis20 protein networkhttps://string-db.org/network/284812.O94682CENP-A recruiting complex protein mis20; Component of the CENP-A recruiting complex that ensures the integrity of mitotic spindles through maintenance of kinetochore factors mis6/CENP-I and cnp1/ [...]
rrp7 protein networkhttps://string-db.org/network/284812.O94683Ribosomal RNA-processing protein 7; Plays an important role in the synthesis of 18S rRNA but is not required for the 5.8S and 25S pathway. Is necessary for the cleavage at site A2 (By similarity) [...]
pmh1 protein networkhttps://string-db.org/network/284812.O94684RNA polymerase II transcription factor B subunit 3; Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated t [...]
ucp8 protein networkhttps://string-db.org/network/284812.O94685UBA domain-containing protein 8.
rpl4302 protein networkhttps://string-db.org/network/284812.O9468660S ribosomal protein L43-B.
tas3 protein networkhttps://string-db.org/network/284812.O94687RNA-induced transcriptional silencing complex protein tas3; Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation and accurate chromosome segregation. [...]
apc15 protein networkhttps://string-db.org/network/284812.O94688Anaphase-promoting complex subunit 15; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through [...]
SPBC83.05 protein networkhttps://string-db.org/network/284812.O94689Mitochondrial escape protein 2; Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May [...]
rtc6 protein networkhttps://string-db.org/network/284812.O9469054S ribosomal protein c83.06c, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family.
jmj3 protein networkhttps://string-db.org/network/284812.O94691Lid2 complex component jmj3.
rvb2 protein networkhttps://string-db.org/network/284812.O94692RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange o [...]
lin1 protein networkhttps://string-db.org/network/284812.O94693LIN1-like protein; Belongs to the LIN1 family.
emc7 protein networkhttps://string-db.org/network/284812.O94694UPF0620 protein C83.10.
pet2 protein networkhttps://string-db.org/network/284812.O94695Putative transporter C83.11.
rfc5 protein networkhttps://string-db.org/network/284812.O94697Replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1.
wdr74 protein networkhttps://string-db.org/network/284812.O94698Ribosome biogenesis protein nsa1; Involved in the biogenesis of the 60S ribosomal subunit.
SPBC83.16c protein networkhttps://string-db.org/network/284812.O94699Inclusion body clearance protein IML2; Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins. Involved in LD-mediated IB clearing after protein folding str [...]
mbf1 protein networkhttps://string-db.org/network/284812.O94700Multiprotein-bridging factor 1; Transcriptional coactivator that stimulates transcriptional activity by bridging regulatory proteins and TBP, thereby recruiting TBP to promoters occupied by DNA-b [...]
fic1 protein networkhttps://string-db.org/network/284812.O94701Ingression protein fic1; Involved in the ingression of the plasma membrane during cytokinesis, leading to the separation of the daughter cells. Unlike its S.cerevisiae ortholog INN1, it does not [...]
erm1 protein networkhttps://string-db.org/network/284812.O94702Putative endoplasmic reticulum metallopeptidase 1; Belongs to the peptidase M28 family. M28B subfamily.
rpa12 protein networkhttps://string-db.org/network/284812.O94703DNA-directed RNA polymerase I subunit RPA12; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
iec3 protein networkhttps://string-db.org/network/284812.O94704INO80 complex subunit 3; Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
cox9 protein networkhttps://string-db.org/network/284812.O94705Cytochrome c oxidase subunit 9, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The res [...]
taf8 protein networkhttps://string-db.org/network/284812.O94706Transcription initiation factor TFIID subunit 8; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA eleme [...]
rxt3 protein networkhttps://string-db.org/network/284812.O94707Transcriptional regulatory protein rxt3; Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histo [...]
SPCC1259.08 protein networkhttps://string-db.org/network/284812.O94708Uncharacterized protein C1259.08.
pdx1 protein networkhttps://string-db.org/network/284812.O94709Probable pyruvate dehydrogenase protein X component, mitochondrial; Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate deh [...]
pgp1 protein networkhttps://string-db.org/network/284812.O94710tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codon [...]
gyp2 protein networkhttps://string-db.org/network/284812.O94711GTPase-activating protein gyp2; Stimulates specifically the GTPase activity of ypt2 and ryh1. Inactivates ryh1 during recycling between the endosome and the Golgi compartments (By similarity).
gid1 protein networkhttps://string-db.org/network/284812.O94712Uncharacterized protein C1259.12c.
meu27 protein networkhttps://string-db.org/network/284812.O94713Meiotic expression up-regulated protein 27; Belongs to the UPF0300 family.
spt2 protein networkhttps://string-db.org/network/284812.O94714Protein spt2; Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin. Required for normal chromatin refolding in the [...]
rps1501 protein networkhttps://string-db.org/network/284812.O9471540S ribosomal protein S15-A.
fta4 protein networkhttps://string-db.org/network/284812.O94716Inner kinetochore subunit fta4; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segre [...]
ers1 protein networkhttps://string-db.org/network/284812.O94717RNA-silencing factor ers1; Involved in RNAi-dependent heterochromatin formation and centromeric silencing. Required for the conversion of centromeric pre- small interfering RNA transcripts into s [...]
ipi1 protein networkhttps://string-db.org/network/284812.O94718Pre-rRNA-processing protein ipi1; Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
mug4 protein networkhttps://string-db.org/network/284812.O94719Meiotically up-regulated gene 4 protein; Has a role in meiosis.
fil1 protein networkhttps://string-db.org/network/284812.O94720GATA zinc finger domain-containing protein C1393.08.
gir2 protein networkhttps://string-db.org/network/284812.O94721RWD domain-containing protein C1393.09c.
ctr4 protein networkhttps://string-db.org/network/284812.O94722Copper transport protein ctr4; Required for high affinity copper (probably reduced Cu I) transport into the cell.
mrpl20 protein networkhttps://string-db.org/network/284812.O9472354S ribosomal protein L20, mitochondrial.
SPCC1393.12 protein networkhttps://string-db.org/network/284812.O94724Uncharacterized protein C1393.12.
duf89 protein networkhttps://string-db.org/network/284812.O94725Damage-control phosphatase SPCC1393.13; Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate (By similar [...]
mnl1 protein networkhttps://string-db.org/network/284812.O94726ER degradation-enhancing alpha-mannosidase-like protein 1; Alpha-mannosidase-like protein involved in endoplasmic reticulum-associated degradation (ERAD). Delivers misfolded glycoproteins to prot [...]
frp2 protein networkhttps://string-db.org/network/284812.O94727Ferric/cupric reductase transmembrane component 2; Metalloreductase responsible for reducing extracellular iron and copper prior to import (By similarity). Catalyzes the reductive uptake of Fe(3+ [...]
SPBC1604.16c protein networkhttps://string-db.org/network/284812.O94728Uncharacterized protein C1604.16c.
tti2 protein networkhttps://string-db.org/network/284812.O94729Uncharacterized protein C1604.17c.
cmp7 protein networkhttps://string-db.org/network/284812.O94730Uncharacterized protein C1604.18c.
trs8501 protein networkhttps://string-db.org/network/284812.O94731Transport protein particle subunit trs85-1; Component of the TRAPP I and TRAPP II complexes. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II seems [...]
SPCC191.01 protein networkhttps://string-db.org/network/284812.O94733Uncharacterized protein C191.01.
cdc37 protein networkhttps://string-db.org/network/284812.O94740Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
git3 protein networkhttps://string-db.org/network/284812.O94744Glucose receptor protein git3; Activates gpa2 when triggered by glucose and then activates adenylate cyclase; Belongs to the G-protein coupled receptor GPR1/git3 family.
mas2 protein networkhttps://string-db.org/network/284812.O94745Probable mitochondrial-processing peptidase subunit alpha; Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequ [...]
bub1 protein networkhttps://string-db.org/network/284812.O94751Checkpoint serine/threonine-protein kinase bub1; Involved in cell cycle checkpoint enforcement. Acts to stabilize the spindle during mitosis. Required for the correct localization of bub3 and mad [...]
edc3 protein networkhttps://string-db.org/network/284812.O94752Enhancer of mRNA-decapping protein 3; Stimulates decapping of both stable and unstable mRNA during mRNA decay. Stimulates decapping presumably by preventing the DCP1-DCP2 decapping complex from a [...]
meu14 protein networkhttps://string-db.org/network/284812.O94756Meiotic expression up-regulated protein 14; Has a role in nuclear division during meiosis II where it stabilizes the proper segregation of the spindle pole bodies. Also has a role in the formatio [...]
cyc1 protein networkhttps://string-db.org/network/284812.P00046Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrom [...]
adh1 protein networkhttps://string-db.org/network/284812.P00332Alcohol dehydrogenase.
cdc10 protein networkhttps://string-db.org/network/284812.P01129Start control protein cdc10; Major component of the cell cycle transcription factor complex MBF (MCB binding factor, also known as DSC1), that controls G1- S phase specific gene expression. Invol [...]
cdc2 protein networkhttps://string-db.org/network/284812.P04551Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required for entry into S-phase and mitosis. When complexed with cig2, plays a role in G1-S phase tr [...]
nda2 protein networkhttps://string-db.org/network/284812.P04688Tubulin alpha-1 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha c [...]
atb2 protein networkhttps://string-db.org/network/284812.P04689Tubulin alpha-2 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha c [...]
hta1 protein networkhttps://string-db.org/network/284812.P04909Histone H2A-alpha; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to [...]
hta2 protein networkhttps://string-db.org/network/284812.P04910Histone H2A-beta; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to t [...]
htb1 protein networkhttps://string-db.org/network/284812.P04913Histone H2B-alpha; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones [...]
nda3 protein networkhttps://string-db.org/network/284812.P05219Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chai [...]
cob1 protein networkhttps://string-db.org/network/284812.P05501Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates ele [...]
SPMIT.06 protein networkhttps://string-db.org/network/284812.P05511Uncharacterized 91 kDa protein in cob intron.
rpl3702 protein networkhttps://string-db.org/network/284812.P0573360S ribosomal protein L37-B; Binds to the 23S rRNA.
rpl1901 protein networkhttps://string-db.org/network/284812.P0573460S ribosomal protein L19-A; Belongs to the eukaryotic ribosomal protein eL19 family.
rps601 protein networkhttps://string-db.org/network/284812.P0575240S ribosomal protein S6-A; Belongs to the eukaryotic ribosomal protein eS6 family.
rps21 protein networkhttps://string-db.org/network/284812.P0576440S ribosomal protein S21; Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to [...]
rpl39 protein networkhttps://string-db.org/network/284812.P0576760S ribosomal protein L39.
cam1 protein networkhttps://string-db.org/network/284812.P05933Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a numb [...]
cdc25 protein networkhttps://string-db.org/network/284812.P06652M-phase inducer phosphatase; This protein functions as a dosage-dependent inducer in mitotic control. It is a tyrosine protein phosphatase required for progression of the cell cycle. It may direc [...]
cdr1 protein networkhttps://string-db.org/network/284812.P07334Mitosis inducer protein kinase cdr1; This protein, a dose-dependent mitotic inducer, appears to function as a negative regulator of mitosis inhibitor wee1 by phosphorylating and inactivating it.
wee1 protein networkhttps://string-db.org/network/284812.P07527Mitosis inhibitor protein kinase wee1; Protein kinase that acts both on serines and on tyrosines. It acts as a dosage-dependent negative regulator of entry into mitosis (G2 to M transition). Phos [...]
cox1 protein networkhttps://string-db.org/network/284812.P07657Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain [...]
tpi1 protein networkhttps://string-db.org/network/284812.P07669Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.
top1 protein networkhttps://string-db.org/network/284812.P07799DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA dup [...]
mei3 protein networkhttps://string-db.org/network/284812.P0809021 kDa protein inducing meiosis and sporulation; This protein, expressed under control of the mating-type locus, induces meiosis and sporulation in fission yeast. It down regulates the ran1/pat1 [...]
pho1 protein networkhttps://string-db.org/network/284812.P08091Acid phosphatase.
pat1 protein networkhttps://string-db.org/network/284812.P08092Negative regulator of sexual conjugation and meiosis; This protein is a negative regulator of both sexual conjugation and meiosis. It phosphorylates mei2. It blocks the onset of meiosis until con [...]
rpp201 protein networkhttps://string-db.org/network/284812.P0809460S acidic ribosomal protein P2-alpha; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family.
top2 protein networkhttps://string-db.org/network/284812.P08096DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
suc1 protein networkhttps://string-db.org/network/284812.P08463Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinase (cdc2) and is essential for its biological function; Belongs to the CKS family.
ras1 protein networkhttps://string-db.org/network/284812.P08647Ras-like protein 1; Participates in the process of sexual differentiation and the determination of cell shape. Essential for mating and for recognition of the mating pheromone, but not for vegeta [...]
mei2 protein networkhttps://string-db.org/network/284812.P08965Meiosis protein mei2; Crucial for commitment to meiosis but it is not sufficient itself for the commitment. May be a splicing regulator.
fbp1 protein networkhttps://string-db.org/network/284812.P09202Fructose-1,6-bisphosphatase.
hhf1 protein networkhttps://string-db.org/network/284812.P09322Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby [...]
pma1 protein networkhttps://string-db.org/network/284812.P09627Plasma membrane ATPase 1; The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The res [...]
hht1 protein networkhttps://string-db.org/network/284812.P09988Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones [...]
ubi3 protein networkhttps://string-db.org/network/284812.P0C016Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isope [...]
ten1 protein networkhttps://string-db.org/network/284812.P0C5Y7Protein ten1; Required for telomere maintenance.
ubi5 protein networkhttps://string-db.org/network/284812.P0C8R3Ubiquitin-40S ribosomal protein S27b; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isope [...]
nxt1 protein networkhttps://string-db.org/network/284812.P0CAN8NTF2-related export protein 1; Stimulator of protein export for NES-containing proteins (By similarity). Also plays a role in mRNA nuclear export.
dpc13 protein networkhttps://string-db.org/network/284812.P0CAN9Uncharacterized protein PB1A10.16, mitochondrial.
mzt1 protein networkhttps://string-db.org/network/284812.P0CF96Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the microtubule organizing center (MTOC).
ubi4 protein networkhttps://string-db.org/network/284812.P0CG72Polyubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a [...]
ubi1 protein networkhttps://string-db.org/network/284812.P0CH06Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an iso [...]
ubi2 protein networkhttps://string-db.org/network/284812.P0CH07Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an iso [...]
SPBC1348.15 protein networkhttps://string-db.org/network/284812.P0CS84Uncharacterized protein C1348.15.
SPBCPT2R1.03 protein networkhttps://string-db.org/network/284812.P0CS85Uncharacterized protein CPT2R1.03.
SPBC1348.01 protein networkhttps://string-db.org/network/284812.P0CS86UPF0494 membrane protein C1348.01.
SPAC959.06c protein networkhttps://string-db.org/network/284812.P0CS92Uncharacterized protein C959.06c.
tlh1 protein networkhttps://string-db.org/network/284812.P0CT33ATP-dependent DNA helicase tlh1; Exhibits ATP-dependent 3' to 5' DNA helicase activity and has a role in telomerase-independent telomere maintenance. Belongs to the helicase family. RecQ subfamil [...]
Tf2-1 protein networkhttps://string-db.org/network/284812.P0CT34Transposon Tf2-1 polyprotein.
Tf2-2 protein networkhttps://string-db.org/network/284812.P0CT35Transposon Tf2-2 polyprotein.
Tf2-3 protein networkhttps://string-db.org/network/284812.P0CT36Transposon Tf2-3 polyprotein.
Tf2-4 protein networkhttps://string-db.org/network/284812.P0CT37Transposon Tf2-4 polyprotein.
Tf2-5 protein networkhttps://string-db.org/network/284812.P0CT38Transposon Tf2-5 polyprotein.
Tf2-6 protein networkhttps://string-db.org/network/284812.P0CT39Transposon Tf2-6 polyprotein.
Tf2-9 protein networkhttps://string-db.org/network/284812.P0CT40Transposon Tf2-9 polyprotein.
Tf2-12 protein networkhttps://string-db.org/network/284812.P0CT41Transposon Tf2-12 polyprotein.
Tf2-7 protein networkhttps://string-db.org/network/284812.P0CT42Transposon Tf2-7 polyprotein.
Tf2-8 protein networkhttps://string-db.org/network/284812.P0CT43Transposon Tf2-8 polyprotein.
tef101 protein networkhttps://string-db.org/network/284812.P0CT53Elongation factor 1-alpha-A; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation fac [...]
tef102 protein networkhttps://string-db.org/network/284812.P0CT54Elongation factor 1-alpha-B; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation fac [...]
tef103 protein networkhttps://string-db.org/network/284812.P0CT55Elongation factor 1-alpha-B/C; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation f [...]
rps1401 protein networkhttps://string-db.org/network/284812.P0CT5640S ribosomal protein S14-A.
rps1402 protein networkhttps://string-db.org/network/284812.P0CT5740S ribosomal protein S14-B.
rps2201 protein networkhttps://string-db.org/network/284812.P0CT5840S ribosomal protein S22-A.
rps2202 protein networkhttps://string-db.org/network/284812.P0CT5940S ribosomal protein S22-B.
rpl2301 protein networkhttps://string-db.org/network/284812.P0CT6060S ribosomal protein L23-A.
rpl2302 protein networkhttps://string-db.org/network/284812.P0CT6160S ribosomal protein L23-B.
rps3001 protein networkhttps://string-db.org/network/284812.P0CT6240S ribosomal protein S30-A.
rps3002 protein networkhttps://string-db.org/network/284812.P0CT6340S ribosomal protein S30-B.
rps1601 protein networkhttps://string-db.org/network/284812.P0CT6440S ribosomal protein S16-A.
rps1602 protein networkhttps://string-db.org/network/284812.P0CT6540S ribosomal protein S16-B.
rps1801 protein networkhttps://string-db.org/network/284812.P0CT6640S ribosomal protein S18-A; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.
rps1802 protein networkhttps://string-db.org/network/284812.P0CT6740S ribosomal protein S18-B; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.
rpl2001 protein networkhttps://string-db.org/network/284812.P0CT6860S ribosomal protein L20-A.
rpl2002 protein networkhttps://string-db.org/network/284812.P0CT6960S ribosomal protein L20-B.
rpl801 protein networkhttps://string-db.org/network/284812.P0CT7060S ribosomal protein L2-A.
rpl802 protein networkhttps://string-db.org/network/284812.P0CT7160S ribosomal protein L2-B.
rpl803 protein networkhttps://string-db.org/network/284812.P0CT7260S ribosomal protein L2-C.
rps1101 protein networkhttps://string-db.org/network/284812.P0CT7340S ribosomal protein S11-A.
rps1102 protein networkhttps://string-db.org/network/284812.P0CT7440S ribosomal protein S11-B.
rps23 protein networkhttps://string-db.org/network/284812.P0CT7540S ribosomal protein S23-A; Belongs to the universal ribosomal protein uS12 family.
rps2302 protein networkhttps://string-db.org/network/284812.P0CT7640S ribosomal protein S23-B; Belongs to the universal ribosomal protein uS12 family.
rpl1101 protein networkhttps://string-db.org/network/284812.P0CT7760S ribosomal protein L11-A; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger [...]
rpl1102 protein networkhttps://string-db.org/network/284812.P0CT7860S ribosomal protein L11-B; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger [...]
rps2801 protein networkhttps://string-db.org/network/284812.P0CT7940S ribosomal protein S28-A.
rps2802 protein networkhttps://string-db.org/network/284812.P0CT8040S ribosomal protein S28-B.
rpl4101 protein networkhttps://string-db.org/network/284812.P0CT8160S ribosomal protein L41-A.
rpl4102 protein networkhttps://string-db.org/network/284812.P0CT8260S ribosomal protein L41-B.
rpl1201 protein networkhttps://string-db.org/network/284812.P0CT8360S ribosomal protein L12-A; This protein binds directly to 26S ribosomal RNA. Belongs to the universal ribosomal protein uL11 family.
rpl1202 protein networkhttps://string-db.org/network/284812.P0CT8460S ribosomal protein L12-B; This protein binds directly to 26S ribosomal RNA. Belongs to the universal ribosomal protein uL11 family.
SPBPB10D8.04c protein networkhttps://string-db.org/network/284812.P0CT94Uncharacterized transporter SPBPB10D8.04c.
SPBPB10D8.05c protein networkhttps://string-db.org/network/284812.P0CT95Uncharacterized transporter SPBPB10D8.05c.
SPBPB10D8.06c protein networkhttps://string-db.org/network/284812.P0CT96Uncharacterized transporter SPBPB10D8.06c.
SPBPB10D8.07c protein networkhttps://string-db.org/network/284812.P0CT97Uncharacterized transporter SPBPB10D8.07c.
SPAC212.01c protein networkhttps://string-db.org/network/284812.P0CT98UPF0494 membrane protein SPAC212.01c.
ayr2 protein networkhttps://string-db.org/network/284812.P0CU00Uncharacterized oxidoreductase SPAC977.08.
SPBC1348.09 protein networkhttps://string-db.org/network/284812.P0CU01Uncharacterized oxidoreductase SPBC1348.09.
plb4 protein networkhttps://string-db.org/network/284812.P0CU02Putative lysophospholipase SPAC977.09c; Catalyzes the release of fatty acids from lysophospholipids.
SPBC1348.10c protein networkhttps://string-db.org/network/284812.P0CU03Putative lysophospholipase SPBC1348.10c; Catalyzes the release of fatty acids from lysophospholipids.
SPBC1348.08c protein networkhttps://string-db.org/network/284812.P0CU04Putative cell agglutination protein SPAC1348.08c; May be involved in agglutination during conjugation or other aspects of colony formation.
pfl6 protein networkhttps://string-db.org/network/284812.P0CU05Putative cell agglutination protein pfl6; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed ; Belon [...]
ftm3 protein networkhttps://string-db.org/network/284812.P0CU06UPF0742 protein SPAC750.04c.
yip11 protein networkhttps://string-db.org/network/284812.P0CU08Survival of motor neuron protein-interacting protein yip11; Belongs to the gemin-2 family.
yip12 protein networkhttps://string-db.org/network/284812.P0CU09Survival of motor neuron protein-interacting protein yip12; Belongs to the gemin-2 family.
SPAC750.02c protein networkhttps://string-db.org/network/284812.P0CU10Uncharacterized transporter SPAC750.02c.
SPBPB2B2.15 protein networkhttps://string-db.org/network/284812.P0CU12VEL1-related protein SPBPB2B2.15; Belongs to the VEL1 family.
SPBC1348.06c protein networkhttps://string-db.org/network/284812.P0CU13VEL1-related protein SPBC1348.06c; Belongs to the VEL1 family.
ftm5 protein networkhttps://string-db.org/network/284812.P0CU14Uncharacterized membrane protein SPBC1348.02.
SPBPB2B2.19c protein networkhttps://string-db.org/network/284812.P0CU15Uncharacterized membrane protein SPBPB2B2.19c.
ftm1 protein networkhttps://string-db.org/network/284812.P0CU16Uncharacterized membrane protein SPAC977.01.
rpn501 protein networkhttps://string-db.org/network/284812.P0CU1726S proteasome regulatory subunit rpn501; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Required for proper prot [...]
rpn502 protein networkhttps://string-db.org/network/284812.P0CU1826S proteasome regulatory subunit rpn502; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Required for proper prot [...]
fex1 protein networkhttps://string-db.org/network/284812.P0CU19Fluoride export protein 1; Fluoride channel required for the rapid expulsion of cytoplasmic fluoride; Belongs to the fluoride exporter Fluc/FEX family.
fex2 protein networkhttps://string-db.org/network/284812.P0CU20Fluoride export protein 2; Fluoride channel required for the rapid expulsion of cytoplasmic fluoride; Belongs to the fluoride exporter Fluc/FEX family.
SPBC713.14c protein networkhttps://string-db.org/network/284812.P0CU21Uncharacterized protein SPBC713.14c.
tom6 protein networkhttps://string-db.org/network/284812.P0CU22Uncharacterized protein SPAC823.17.
ina17 protein networkhttps://string-db.org/network/284812.P0CU26Inner membrane assembly complex subunit 17; Component of the INA complex (INAC) that promotes the biogenesis of mitochondrial F(1)F(0)-ATP synthase. INAC facilitates the assembly of the periphera [...]
mat3-Mi protein networkhttps://string-db.org/network/284812.P0CY14Silenced mating-type M-specific polypeptide Mi; Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression [...]
mat1-Mi protein networkhttps://string-db.org/network/284812.P0CY15Mating-type M-specific polypeptide Mi; Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cel [...]
mat3-Mc protein networkhttps://string-db.org/network/284812.P0CY16Silenced mating-type M-specific polypeptide Mc; Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression [...]
mat1-Mc protein networkhttps://string-db.org/network/284812.P0CY17Mating-type M-specific polypeptide Mc; Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cel [...]
nuc2 protein networkhttps://string-db.org/network/284812.P10505Anaphase-promoting complex subunit 3; Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through m [...]
byr1 protein networkhttps://string-db.org/network/284812.P10506Protein kinase byr1; Serine/threonine protein kinase involved in conjugation and sporulation. It is thought that it is phosphorylated by the byr2 protein kinase and that it can phosphorylate the [...]
hht3 protein networkhttps://string-db.org/network/284812.P10651Histone H3.3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones there [...]
cdc13 protein networkhttps://string-db.org/network/284812.P10815G2/mitotic-specific cyclin cdc13; Essential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the cdc2 protein kinase to form MPF. G2/M cyclins accumulate steadil [...]
act1 protein networkhttps://string-db.org/network/284812.P10989Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
ypt1 protein networkhttps://string-db.org/network/284812.P11620GTP-binding protein ypt1; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle betwe [...]
cdc17 protein networkhttps://string-db.org/network/284812.P12000DNA ligase 1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair; Belongs to the ATP-dependent DNA ligase family.
dis2 protein networkhttps://string-db.org/network/284812.P13681Serine/threonine-protein phosphatase PP1-1; Essential role in cell cycle control. PP1 is perhaps required for exit from mitosis.
crm1 protein networkhttps://string-db.org/network/284812.P14068Exportin-1; Receptor for the leucine-rich nuclear export signal (NES). Belongs to the exportin family.
cox3 protein networkhttps://string-db.org/network/284812.P14575Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain [...]
cyr1 protein networkhttps://string-db.org/network/284812.P14605Adenylate cyclase; Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.
ura4 protein networkhttps://string-db.org/network/284812.P14965Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.
ral2 protein networkhttps://string-db.org/network/284812.P15258Protein ral2; Essential for mating and for recognition of the mating pheromone, and for the determination of cell shape. Implicated in activation of the ras1 protein.
nuc1 protein networkhttps://string-db.org/network/284812.P15398DNA-directed RNA polymerase I subunit rpa1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalyt [...]
ade6 protein networkhttps://string-db.org/network/284812.P15567Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.
rpp101 protein networkhttps://string-db.org/network/284812.P1747660S acidic ribosomal protein P1-alpha 1; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family.
rpp102 protein networkhttps://string-db.org/network/284812.P1747760S acidic ribosomal protein P1-alpha 3; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family.
rpp202 protein networkhttps://string-db.org/network/284812.P1747860S acidic ribosomal protein P2-beta; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family.
ryh1 protein networkhttps://string-db.org/network/284812.P17608GTP-binding protein ryh1; Has a role in retrograde traffricking of proteins from the endosome to the Golgi. Involved in protein transport to the plasma membrane. Involved in the secretory pathway [...]
ypt2 protein networkhttps://string-db.org/network/284812.P17609GTP-binding protein ypt2; Protein transport. Probably involved in vesicular traffic (By similarity).
ypt3 protein networkhttps://string-db.org/network/284812.P17610GTP-binding protein ypt3; Has a role in retrograde traffricking of proteins from the endosome to the Golgi. Involved in the secretory pathway where it has a role in acid phosphatase secretion; Be [...]
tbp1 protein networkhttps://string-db.org/network/284812.P17871TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional ste [...]
rlp7 protein networkhttps://string-db.org/network/284812.P1793760S ribosomal protein L7-A.
ppi1 protein networkhttps://string-db.org/network/284812.P18253Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophi [...]
cut1 protein networkhttps://string-db.org/network/284812.P18296Separin; Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the rad21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cyc [...]
leu1 protein networkhttps://string-db.org/network/284812.P188693-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
ipp1 protein networkhttps://string-db.org/network/284812.P19117Inorganic pyrophosphatase; Belongs to the PPase family.
ade1 protein networkhttps://string-db.org/network/284812.P20772Phosphoribosylformylglycinamidine cyclo-ligase; In the N-terminal section; belongs to the GARS family.
cut2 protein networkhttps://string-db.org/network/284812.P21135Securin; Regulatory protein, which plays a central role in chromosome stability. Probably acts by blocking the action of key proteins. During the mitosis, it blocks separase/cut1 function, preven [...]
cox2 protein networkhttps://string-db.org/network/284812.P21534Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain [...]
atp6 protein networkhttps://string-db.org/network/284812.P21535ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated [...]
atp8 protein networkhttps://string-db.org/network/284812.P21536ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated [...]
atp9 protein networkhttps://string-db.org/network/284812.P21537ATP synthase subunit 9, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
var1 protein networkhttps://string-db.org/network/284812.P21547Ribosomal protein var1, mitochondrial; Essential for mitochondrial protein synthesis and required for the maturation of small ribosomal subunits.
srp54 protein networkhttps://string-db.org/network/284812.P21565Signal recognition particle 54 kDa protein homolog; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associ [...]
gpd1 protein networkhttps://string-db.org/network/284812.P21696Glycerol-3-phosphate dehydrogenase [NAD(+)] 1; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
sdh2 protein networkhttps://string-db.org/network/284812.P21911Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial elec [...]
atp2 protein networkhttps://string-db.org/network/284812.P22068ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane w [...]
cta3 protein networkhttps://string-db.org/network/284812.P22189Calcium-transporting ATPase 3; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium.
cox1-I2b protein networkhttps://string-db.org/network/284812.P22190Uncharacterized cox1 intron-2 37.2 kDa protein.
cox1-I1b protein networkhttps://string-db.org/network/284812.P22191Uncharacterized cox1 intron-1 45.6 kDa protein.
pac1 protein networkhttps://string-db.org/network/284812.P22192Double-strand-specific pac1 ribonuclease; Digests double-stranded RNA. Converts long double-stranded RNAs into short oligonucleotides, leaving 5'-phosphates on their cleavage products. Probably i [...]
rad1 protein networkhttps://string-db.org/network/284812.P22193DNA damage checkpoint control protein rad1; Recombinational reparation of DNA damages induced by UV and gamma radiation.
sds22 protein networkhttps://string-db.org/network/284812.P22194Protein phosphatase 1 regulatory subunit SDS22; Essential for the mitotic metaphase/anaphase transition. Positively modulates protein phosphatase-1, possibly by forming a repeating helical rod th [...]
ssc1 protein networkhttps://string-db.org/network/284812.P22774Heat shock 70 kDa protein, mitochondrial; Belongs to the heat shock protein 70 family.
kin1 protein networkhttps://string-db.org/network/284812.P22987Protein kinase kin1; Has a role in establishing the characteristic rod cell shape. Important for cell polarity and is involved in directing growth to the cell ends; Belongs to the protein kinase [...]
rhp6 protein networkhttps://string-db.org/network/284812.P23566Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Component of the histone H2B ubiquitin ligase complex (HULC) which plays a role in transcripti [...]
ppa1 protein networkhttps://string-db.org/network/284812.P23635Minor serine/threonine-protein phosphatase PP2A-1 catalytic subunit; Essential role in cell cycle control. PP2A may be involved in controlling the entry into mitosis, possibly acting as an inhibi [...]
ppa2 protein networkhttps://string-db.org/network/284812.P23636Major serine/threonine-protein phosphatase PP2A-2 catalytic subunit; Essential role in cell cycle control. PP2A may be involved in controlling the entry into mitosis, possibly acting as an inhibi [...]
sds21 protein networkhttps://string-db.org/network/284812.P23880Serine/threonine-protein phosphatase PP1-2; Essential role in cell cycle control. PP1 is perhaps required for exit from mitosis; Belongs to the PPP phosphatase family. PP-1 subfamily.
cut7 protein networkhttps://string-db.org/network/284812.P24339Kinesin-like protein cut7; Could be a spindle pole body motor. On transition from G2 to M phase of the cell cycle, the spindle pole body duplicates; the daughter pole bodies seed microtubules whi [...]
atp1 protein networkhttps://string-db.org/network/284812.P24487ATP synthase subunit alpha, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane [...]
php2 protein networkhttps://string-db.org/network/284812.P24488Transcriptional activator hap2; Global regulator of respiratory functions in yeast cells. It belongs to a complex that binds to the sequence CCAAT located upstream of genes involved in mitochondr [...]
dbp2 protein networkhttps://string-db.org/network/284812.P24782ATP-dependent RNA helicase dbp2; ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
cig1 protein networkhttps://string-db.org/network/284812.P24865G2/mitotic-specific cyclin cig1; Required for efficient passage of the G1/S transition.
puc1 protein networkhttps://string-db.org/network/284812.P25009Cyclin puc1; Function in exit from the mitotic cycle. Contributes to negative regulation of the timing of sexual development in fission yeast, and functions at the transition between cycling and [...]
gtb1 protein networkhttps://string-db.org/network/284812.P25295Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting th [...]
rpl702 protein networkhttps://string-db.org/network/284812.P2545760S ribosomal protein L7-B.
rad9 protein networkhttps://string-db.org/network/284812.P26306DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. R [...]
msh3 protein networkhttps://string-db.org/network/284812.P26359DNA mismatch repair protein msh3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with msh2 to form MutS beta, which binds to DNA mismatches thereby initiating [...]
rad15 protein networkhttps://string-db.org/network/284812.P26659General transcription and DNA repair factor IIH helicase subunit XPD; ATP-dependent 5'-3' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, whic [...]
ste6 protein networkhttps://string-db.org/network/284812.P26674Protein ste6; Promotes the exchange of RAS-bound GDP by GTP. This protein is essential for mating.
pyp1 protein networkhttps://string-db.org/network/284812.P27574Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.
gpa1 protein networkhttps://string-db.org/network/284812.P27584Guanine nucleotide-binding protein alpha-1 subunit; Implicated in the mating and sporulation pathway. Probably coupled to mating-factor receptors. May act in concert with Ras1; Belongs to the G-a [...]
spk1 protein networkhttps://string-db.org/network/284812.P27638Mitogen-activated protein kinase spk1; Involved in mating signal transduction pathway.
pol1 protein networkhttps://string-db.org/network/284812.P28040DNA polymerase alpha catalytic subunit; Polymerase alpha in a complex with DNA primase is a replicative polymerase; Belongs to the DNA polymerase type-B family.
rps13 protein networkhttps://string-db.org/network/284812.P2818940S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.
rad13 protein networkhttps://string-db.org/network/284812.P28706DNA repair protein rad13; Single-stranded DNA endonuclease involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Essential for the incision step of exc [...]
pim1 protein networkhttps://string-db.org/network/284812.P28745Protein pim1; Promotes the exchange of Ran(spi1)-bound GDP by GTP. Involved in the control of mitosis. Regulates a variety of nuclear events, including mitotic check-point, chromosome decondensat [...]
spi1 protein networkhttps://string-db.org/network/284812.P28748GTP-binding nuclear protein spi1; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export.
sod1 protein networkhttps://string-db.org/network/284812.P28758Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family.
byr2 protein networkhttps://string-db.org/network/284812.P28829Protein kinase byr2; Serine/threonine protein kinase involved in conjugation and sporulation. It is thought that it phosphorylates the byr1 protein kinase which itself phosphorylate the spk1 kina [...]
pma2 protein networkhttps://string-db.org/network/284812.P28876Plasma membrane ATPase 2; The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The res [...]
mcm4 protein networkhttps://string-db.org/network/284812.P29458DNA replication licensing factor mcm4; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiat [...]
cdc27 protein networkhttps://string-db.org/network/284812.P30261DNA polymerase delta subunit 3.
mik1 protein networkhttps://string-db.org/network/284812.P30290Mitosis inhibitor protein kinase mik1; Protein kinase that acts both on serines and on tyrosines. It acts as a negative regulator of entry into mitosis (G2 to M transition). Phosphorylates and in [...]
cdc6 protein networkhttps://string-db.org/network/284812.P30316DNA polymerase delta catalytic subunit; Catalytic component of DNA polymerase delta (DNA polymerase III) which participates in chromosomal DNA replication. Required during synthesis of the laggin [...]
chs1 protein networkhttps://string-db.org/network/284812.P30597Chitin synthase 1; Plays a major role in cell wall biogenesis.
pts1 protein networkhttps://string-db.org/network/284812.P30655Probable proteasome subunit beta type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent t [...]
mcm3 protein networkhttps://string-db.org/network/284812.P30666DNA replication licensing factor mcm3; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiat [...]
rad21 protein networkhttps://string-db.org/network/284812.P30776Cohesin subunit rad21; Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle. The cohesin complex is required for the cohesion of sister chromatids after D [...]
obr1 protein networkhttps://string-db.org/network/284812.P30821P25 protein; Unknown. Target of pap1 transcription factor. Confers brefeldin A resistance in S.pombe; Belongs to the WrbA family.
pabp protein networkhttps://string-db.org/network/284812.P31209Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability [...]
arg3 protein networkhttps://string-db.org/network/284812.P31317Ornithine carbamoyltransferase, mitochondrial; Ornithine carbamoyltransferase involved in the synthesis of arginine from glutamate via ornithine and the urea cycle.
arg11 protein networkhttps://string-db.org/network/284812.P31318N-acetyl-gamma-glutamyl-phosphate reductase; In the C-terminal section; belongs to the NAGSA dehydrogenase family.
map3 protein networkhttps://string-db.org/network/284812.P31397Pheromone M-factor receptor; Receptor for the peptide pheromone M-factor, a mating factor of S.pombe. Pheromone signaling is essential for initiation of meiosis in S.pombe; M-factor signaling alo [...]
vma1 protein networkhttps://string-db.org/network/284812.P31406V-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular comp [...]
vma2 protein networkhttps://string-db.org/network/284812.P31411V-type proton ATPase subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic [...]
gtp1 protein networkhttps://string-db.org/network/284812.P32235GTP-binding protein 1; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
rad4 protein networkhttps://string-db.org/network/284812.P32372S-M checkpoint control protein rad4; Essential component for DNA replication and also the checkpoint control system which couples S and M phases. May directly or indirectly interact with chromati [...]
arp3 protein networkhttps://string-db.org/network/284812.P32390Actin-related protein 3; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting fact [...]
cwg2 protein networkhttps://string-db.org/network/284812.P32434Geranylgeranyl transferase type-1 subunit beta; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to proteins having the C-terminal C-A-A-L where A is an aliph [...]
pyp2 protein networkhttps://string-db.org/network/284812.P32586Tyrosine-protein phosphatase 2; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.
pyp3 protein networkhttps://string-db.org/network/284812.P32587Tyrosine-protein phosphatase 3; Contributes to dephosphorylation of tyrosine 15 of cdc2.
ura3 protein networkhttps://string-db.org/network/284812.P32747Dihydroorotate dehydrogenase (quinone), mitochondrial; In the de novo pyrimidine biosynthesis pathway, catalyzes the stereospecific oxidation of (S)-dihydroorotate to orotate with reduction of fl [...]
sxa2 protein networkhttps://string-db.org/network/284812.P32825Carboxypeptidase sxa2; Involved in degradation or processing of the mating pheromones. Its loss causes a persistent response to the pheromones. It may be required for stabilization of enzymes tha [...]
sxa1 protein networkhttps://string-db.org/network/284812.P32834Aspartic proteinase sxa1; Involved in degradation or processing of the mating pheromones. Its loss may cause a persistent response to the pheromones. It may cleave the mating pheromone M-factor. [...]
adk1 protein networkhttps://string-db.org/network/284812.P33075Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
gap1 protein networkhttps://string-db.org/network/284812.P33277GTPase-activating protein; Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase activity of Ras1.
res1 protein networkhttps://string-db.org/network/284812.P33520Cell division cycle-related protein res1/sct1; Acts as a positive regulator of the mitotic cell cycle and as a negative regulator of sexual differentiation. May be involved in the transcriptional [...]
bsu1 protein networkhttps://string-db.org/network/284812.P33532Vitamin B6 transporter bsu1; Thiamine-regulated, high affinity import carrier of pyridoxine, pyridoxal and pyridoxamine. Also imports, but does not export, amiloride and so confers sensitivity. B [...]
wis1 protein networkhttps://string-db.org/network/284812.P33886Protein kinase wis1; Dosage-dependent regulator of mitosis with serine/ threonine protein kinase activity. May play a role in the integration of nutritional sensing with the control over entry in [...]
mfm1 protein networkhttps://string-db.org/network/284812.P34068M-factor; M-factor is a mating pheromone produced by M-type mating cells. All three mfm genes contribute to the production of M-factor.
mfm2 protein networkhttps://string-db.org/network/284812.P34069M-factor; M-factor is a mating pheromone produced by M-type mating cells. All three mfm genes contribute to the production of M-factor.
chk1 protein networkhttps://string-db.org/network/284812.P34208Serine/threonine-protein kinase chk1; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA d [...]
fib1 protein networkhttps://string-db.org/network/284812.P35551rRNA 2'-O-methyltransferase fibrillarin; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzin [...]
gsa1 protein networkhttps://string-db.org/network/284812.P35669Glutathione synthetase large chain; Belongs to the eukaryotic GSH synthase family.
rpl402 protein networkhttps://string-db.org/network/284812.P3567960S ribosomal protein L4-A.
erg4 protein networkhttps://string-db.org/network/284812.P36209Delta(24(24(1)))-sterol reductase.
arf1 protein networkhttps://string-db.org/network/284812.P36579ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus; Belongs to the small GTPase superfamily. Arf [...]
fba1 protein networkhttps://string-db.org/network/284812.P36580Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphat [...]
cnx1 protein networkhttps://string-db.org/network/284812.P36581Calnexin homolog; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within [...]
pck1 protein networkhttps://string-db.org/network/284812.P36582Protein kinase C-like 1; Involved in the control of the cell shape. Target of the inhibitor staurosporine; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfam [...]
pck2 protein networkhttps://string-db.org/network/284812.P36583Protein kinase C-like 2; Involved in the control of the cell shape. Target of the inhibitor staurosporine; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfam [...]
rpl302 protein networkhttps://string-db.org/network/284812.P3658460S ribosomal protein L3-B; Belongs to the universal ribosomal protein uL3 family.
rpl2802 protein networkhttps://string-db.org/network/284812.P3658560S ribosomal protein L28-A.
ypt5 protein networkhttps://string-db.org/network/284812.P36586GTP-binding protein ypt5; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.
ccr1 protein networkhttps://string-db.org/network/284812.P36587NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome [...]
cdc14 protein networkhttps://string-db.org/network/284812.P36589Cell division control protein 14; Has a role in the septation initiation network (SIN) required for cytokinesis.
tmp1 protein networkhttps://string-db.org/network/284812.P36590Thymidylate kinase; Catalyzes the conversion of dTMP to dTDP.
dfr1 protein networkhttps://string-db.org/network/284812.P36591Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
rad52 protein networkhttps://string-db.org/network/284812.P36592DNA repair and recombination protein rad22; Active in the repair of DNA damage and in mating-type switching. Probably involved in the repair of DNA double-strands breaks. Has a role in promoting [...]
rpb1 protein networkhttps://string-db.org/network/284812.P36594DNA-directed RNA polymerase II subunit rpb1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and cataly [...]
rpb6 protein networkhttps://string-db.org/network/284812.P36595DNA-directed RNA polymerases I, II, and III subunit RPABC2; DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Com [...]
erg9 protein networkhttps://string-db.org/network/284812.P36596Squalene synthase; Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. Required for the bios [...]
nmt1 protein networkhttps://string-db.org/network/284812.P365974-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase; Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxy [...]
thi1 protein networkhttps://string-db.org/network/284812.P36598Thiamine repressible genes regulatory protein thi1; Transcription factor that activates the nmt1 promoter. Regulation of thiamine repressible genes. Positively regulates conjugation during meiosi [...]
cgs2 protein networkhttps://string-db.org/network/284812.P365993',5'-cyclic-nucleotide phosphodiesterase.
cgs1 protein networkhttps://string-db.org/network/284812.P36600cAMP-dependent protein kinase regulatory subunit.
rad51 protein networkhttps://string-db.org/network/284812.P36601DNA repair protein rhp51; Required both for recombination and for the repair of DNA damage caused by X-rays. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DN [...]
cdc22 protein networkhttps://string-db.org/network/284812.P36602Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
suc22 protein networkhttps://string-db.org/network/284812.P36603Ribonucleoside-diphosphate reductase small chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; B [...]
bip1 protein networkhttps://string-db.org/network/284812.P36604Endoplasmic reticulum chaperone BiP; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May phy [...]
his3 protein networkhttps://string-db.org/network/284812.P36605Histidinol-phosphate aminotransferase.
nhe1 protein networkhttps://string-db.org/network/284812.P36606Na(+)/H(+) antiporter; Sodium export from cell, takes up external protons in exchange for internal sodium ions. Involved in regulation of pH; Belongs to the fungal Na(+)/H(+) exchanger family.
rad8 protein networkhttps://string-db.org/network/284812.P36607DNA repair protein rad8; Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein rad18 in error-free postreplication DNA repair. Involved in the maintenance [...]
php3 protein networkhttps://string-db.org/network/284812.P36611Transcriptional activator hap3; Belongs to a complex that binds to the sequence CCAAT located upstream of genes involved in mitochondrial electron transport.
rpt2 protein networkhttps://string-db.org/network/284812.P3661226S proteasome regulatory subunit 4 homolog; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency a [...]
mcs2 protein networkhttps://string-db.org/network/284812.P36613Cyclin mcs2; Essential for progression through the cell cycle. Posseses kinase activity that can be detected when myelin basic protein (MBP) is provided as an exogenous substrate; Belongs to the [...]
ppe1 protein networkhttps://string-db.org/network/284812.P36614Serine/threonine-protein phosphatase ppe1; Has a role in chromosome segregation. May provide a dynamic connection between kinetochore microtubules and kinetochore chromatin. Negatively regulates [...]
csk1 protein networkhttps://string-db.org/network/284812.P36615Serine/threonine-protein kinase csk1; Acts as a CAK-activating kinase that specifically activates crk1 of the crk1-mcs2 CAK complex.
dsk1 protein networkhttps://string-db.org/network/284812.P36616Protein kinase dsk1; May play an important role in mitotic control by altering cellular location, degree of phosphorylation and kinase activity. Abundant expression accelerates the exit when cell [...]
rad16 protein networkhttps://string-db.org/network/284812.P36617DNA repair protein rad16; Endonuclease that specifically degrades single-stranded DNA and which is involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-lin [...]
cdc16 protein networkhttps://string-db.org/network/284812.P36618Cell division control protein 16; Has a dual role in the cell cycle. In mitosis, it is involved in maintenance of cdc2 kinase activity. It is subsequently required for regulation of septum format [...]
pmd1 protein networkhttps://string-db.org/network/284812.P36619Leptomycin B resistance protein pmd1; May be a transmembrane transporter of the mating factor, namely P-factor or M-factor. Confers resistance to leptomycin B and to several other antifungal drug [...]
ilv1 protein networkhttps://string-db.org/network/284812.P36620Acetolactate synthase, mitochondrial; Belongs to the TPP enzyme family.
cap1 protein networkhttps://string-db.org/network/284812.P36621Adenylyl cyclase-associated protein; The N-terminal domain binds to adenylyl cyclase, thereby enabling adenylyl cyclase to be activated by upstream regulatory signals, such as Ras. The C-terminal [...]
ste4 protein networkhttps://string-db.org/network/284812.P36622Sexual differentiation protein ste4; Essential for mating and meiosis.
gpm1 protein networkhttps://string-db.org/network/284812.P36623Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
tms1 protein networkhttps://string-db.org/network/284812.P36624Sorbitol dehydrogenase; Polyol dehydrogenase that catalyzes the reversible NAD(+)- dependent oxidation of various sugar alcohols. Is active with D- sorbitol (D-glucitol) as substrate, leading to [...]
rec7 protein networkhttps://string-db.org/network/284812.P36625Meiotic recombination protein rec7; May be involved primarily in the early steps of meiotic recombination.
rec8 protein networkhttps://string-db.org/network/284812.P36626Meiotic recombination protein rec8; Involved primarily in the early steps of meiotic recombination. Required to ensure reductional chromosome segregation. Belongs to the rad21 family.
byr3 protein networkhttps://string-db.org/network/284812.P36627Cellular nucleic acid-binding protein homolog; Acts in the sexual differentiation pathway. Is required for efficient conjugation. Double-stranded DNA-binding protein.
prp2 protein networkhttps://string-db.org/network/284812.P36629Splicing factor U2AF 59 kDa subunit; Necessary for the splicing of pre-mRNA. The SF1-U2AF59-U2AF23 complex has a role in the recognition of the branch site (5'-UACUAAC- 3'), the pyrimidine tract [...]
cig2 protein networkhttps://string-db.org/network/284812.P36630G2/mitotic-specific cyclin cig2; Essential for the control of the cell cycle at the G2/M and G1/S (mitosis) transition. Interacts with the cdc2 protein kinase to form MPF. Interaction with res2 p [...]
ste11 protein networkhttps://string-db.org/network/284812.P36631Transcription factor ste11; Key transcription factor for sexual development. Activates the transcription of the matp, matm, mei2, mfm, ste6 and rgs1 genes. Binds specifically to a DNA fragment ca [...]
rad26 protein networkhttps://string-db.org/network/284812.P36632DNA repair protein rad26; Involved in cell cycle arrest when DNA synthesis is inhibited by hydroxyurea, and in mitosis arrest after treatment with DNA-damaging agents. This protein is S phase-spe [...]
dis3 protein networkhttps://string-db.org/network/284812.P37202Exosome complex exonuclease dis3; Catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradati [...]
rpb3 protein networkhttps://string-db.org/network/284812.P37382DNA-directed RNA polymerase II subunit RPB3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
car1 protein networkhttps://string-db.org/network/284812.P37818Arginase; Belongs to the arginase family.
cut8 protein networkhttps://string-db.org/network/284812.P38937Tethering factor for nuclear proteasome cut8; Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome su [...]
cek1 protein networkhttps://string-db.org/network/284812.P38938Serine/threonine-protein kinase cek1; May facilitate the progression of anaphase through direct or indirect interaction with the cut8 protein.
rad2 protein networkhttps://string-db.org/network/284812.P39750Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhan [...]
cdc3 protein networkhttps://string-db.org/network/284812.P39825Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By bin [...]
cdc5 protein networkhttps://string-db.org/network/284812.P39964Pre-mRNA-splicing factor cdc5; Involved in mRNA splicing and cell cycle control. Belongs to the CEF1 family.
cka1 protein networkhttps://string-db.org/network/284812.P40231Casein kinase II subunit alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Plays a role in the translation of cel [...]
ckb1 protein networkhttps://string-db.org/network/284812.P40232Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit.
cki1 protein networkhttps://string-db.org/network/284812.P40233Casein kinase I homolog 1; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.
cki2 protein networkhttps://string-db.org/network/284812.P40234Casein kinase I homolog 2; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. May contribute to the regulation of morphol [...]
hhp1 protein networkhttps://string-db.org/network/284812.P40235Casein kinase I homolog hhp1; Involved in DNA repair. Has a probable role in repairing alkylated DNA and may regulate the activity of protein(s) involved in double strand break repair caused by g [...]
hhp2 protein networkhttps://string-db.org/network/284812.P40236Casein kinase I homolog hhp2; Involved in DNA repair. May regulate the activity of protein(s) involved in double strand break repair caused by gamma rays; Belongs to the protein kinase superfamil [...]
arg7 protein networkhttps://string-db.org/network/284812.P40369Argininosuccinate lyase.
eno101 protein networkhttps://string-db.org/network/284812.P40370Enolase 1-1.
ptc1 protein networkhttps://string-db.org/network/284812.P40371Protein phosphatase 2C homolog 1; It has a serine and threonine phosphatase activity. Has a specialized role in the heat shock response. May be responsible for the dephosphorylation of hsp90. Als [...]
rpl301 protein networkhttps://string-db.org/network/284812.P4037260S ribosomal protein L3-A; Belongs to the universal ribosomal protein uL3 family.
his1 protein networkhttps://string-db.org/network/284812.P40373ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
his5 protein networkhttps://string-db.org/network/284812.P40374Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.
mae2 protein networkhttps://string-db.org/network/284812.P40375NAD-dependent malic enzyme.
pka1 protein networkhttps://string-db.org/network/284812.P40376cAMP-dependent protein kinase catalytic subunit.
mcm2 protein networkhttps://string-db.org/network/284812.P40377DNA replication licensing factor mcm2; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiat [...]
rep1 protein networkhttps://string-db.org/network/284812.P40379Transcriptional activator protein rec16; Transcriptional activator that controls the onset of premeiotic DNA synthesis by regulating res2 and some other factor(s) in a mei2 independent cascade.
rum1 protein networkhttps://string-db.org/network/284812.P40380Cyclin-dependent kinase inhibitor rum1; Regulator of cell cycle G1 phase progression. Ensures the correct sequence of S phase and mitosis in the cell by acting as an inhibitor of the cdc2 mitotic [...]
swi6 protein networkhttps://string-db.org/network/284812.P40381Chromatin-associated protein swi6; Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Involved in the repression of the silent mating-type loci MAT2 an [...]
cdt1 protein networkhttps://string-db.org/network/284812.P40382Cell division cycle protein cdt1; DNA replication licensing factor, required for pre- replication complex assembly. Faithful duplication of the genetic material requires 'once per cell cycle' DNA [...]
exo2 protein networkhttps://string-db.org/network/284812.P403835'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mR [...]
rec12 protein networkhttps://string-db.org/network/284812.P40384Meiotic recombination protein rec12; Required for formation of the double-strand breaks (DSBs) that initiate meiotic recombination. Required for crossover recombination and chiasmatic segregation [...]
rec6 protein networkhttps://string-db.org/network/284812.P40385Meiotic recombination protein rec6; Required for formation of the rec12-mediated double-strand breaks (DSBs) that initiate meiotic recombination. May be involved primarily in the early steps of m [...]
thi4 protein networkhttps://string-db.org/network/284812.P40386Probable thiamine biosynthetic bifunctional enzyme; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) t [...]
tps1 protein networkhttps://string-db.org/network/284812.P40387Alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Appears to have a role in spore germination. In S.pombe it appears to have no role in the control of the initial steps of glycolysis.
uvi15 protein networkhttps://string-db.org/network/284812.P40388UV-induced protein uvi15; Required for the maintenance of viability of cells in stationary phase and in starvation conditions.
efm2 protein networkhttps://string-db.org/network/284812.P40389Protein-lysine N-methyltransferase rrg1; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 2 and elongation factor 3A.
sap1 protein networkhttps://string-db.org/network/284812.P40847Switch-activating protein 1; Binds to sequences required for mating-type switching. Makes a simultaneous contact with both the alpha and beta domains of the switch-activating site SAS1. Also bind [...]
dhp1 protein networkhttps://string-db.org/network/284812.P408485'-3' exoribonuclease 2; Required for the processing of nuclear mRNA and rRNA precursors. May promote the termination of transcription by RNA polymerase II (By similarity). Essential for vegetati [...]
mfm3 protein networkhttps://string-db.org/network/284812.P40849M-factor; M-factor is a mating pheromone produced by M-type mating cells. All three mfm genes contribute to the production of M-factor.
isp3 protein networkhttps://string-db.org/network/284812.P40899Sexual differentiation process protein isp3.
isp4 protein networkhttps://string-db.org/network/284812.P40900Sexual differentiation process protein isp4; Belongs to the oligopeptide OPT transporter family.
isp5 protein networkhttps://string-db.org/network/284812.P40901Sexual differentiation process putative amino-acid permease isp5; Belongs to the amino acid-polyamine-organocation (APC) superfamily.
isp7 protein networkhttps://string-db.org/network/284812.P40902Sexual differentiation process protein isp7.
isp6 protein networkhttps://string-db.org/network/284812.P40903Sexual differentiation process putative subtilase-type proteinase isp6.
SPAC29A4.02c protein networkhttps://string-db.org/network/284812.P40921Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.
yox1 protein networkhttps://string-db.org/network/284812.P40923MBF complex negative regulatory component yox1; Negative regulatory component of the MBF transcription factor complex involved in cell-cycle G1/S phase-specific gene expression and more particula [...]
lys1 protein networkhttps://string-db.org/network/284812.P40976L-2-aminoadipate reductase; Catalyzes the activation of alpha-aminoadipate by ATP- dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipa [...]
plc1 protein networkhttps://string-db.org/network/284812.P409771-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated [...]
hus5 protein networkhttps://string-db.org/network/284812.P40984SUMO-conjugating enzyme ubc9; Catalyzes the covalent attachment of ubiquitin-like protein SUMO/Smt3 to other proteins. Required for efficient recovery from DNA damage or S-phase arrest and normal [...]
scd1 protein networkhttps://string-db.org/network/284812.P40995Rho guanine nucleotide exchange factor scd1; Required for mating and morphogenesis. May contain a cryptic binding site for cdc42 that is enhanced by binding Ras. Interacts directly with scd2. Pro [...]
scd2 protein networkhttps://string-db.org/network/284812.P40996Protein scd2/ral3; Required for mating and morphogenesis. Interacts directly with scd1 and with cdc42. May bridge and facilitate scd1 and cdc42 interactions.
ceg1 protein networkhttps://string-db.org/network/284812.P40997mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate (By similarity); Belongs to [...]
thi2 protein networkhttps://string-db.org/network/284812.P40998Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole- [...]
pmt1 protein networkhttps://string-db.org/network/284812.P40999tRNA (cytosine(38)-C(5))-methyltransferase; Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp). Can also methylate cytosine 38 in tRNA(Glu), albeit to a lower level, but not t [...]
cps3 protein networkhttps://string-db.org/network/284812.P41000Protein cps3; Responsible for supersensitivity to the spindle poison, isopropyl N-3-chlorophenyl carbamate. Has a role in meiosis.
cut14 protein networkhttps://string-db.org/network/284812.P41003Structural maintenance of chromosomes protein 2; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The [...]
cut3 protein networkhttps://string-db.org/network/284812.P41004Structural maintenance of chromosomes protein 4; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The [...]
mes1 protein networkhttps://string-db.org/network/284812.P41005Protein mes1; Specifically required for meiosis II (MII). Binds to slp1, an activator of the anapahase promoting complex/cyclcosome (APC/C), and counteracts its function in promoting proteolysis [...]
mcm5 protein networkhttps://string-db.org/network/284812.P41389DNA replication licensing factor mcm5; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiat [...]
ade4 protein networkhttps://string-db.org/network/284812.P41390Amidophosphoribosyltransferase.
rna1 protein networkhttps://string-db.org/network/284812.P41391Ran GTPase-activating protein 1; GTPase activator for the nuclear Ras-related regulatory protein spi1 (Ran), converting it to the putatively inactive GDP-bound state.
rad54 protein networkhttps://string-db.org/network/284812.P41410DNA repair protein rhp54; Involved in DNA repair. May have a role in the processing of replication structures during late replication that is different from its role in the repair of radiation da [...]
cdc18 protein networkhttps://string-db.org/network/284812.P41411Cell division control protein 18; Part of the checkpoint control that prevents mitosis from occurring until S phase is completed. Plays a key role in coupling S phase to start and mitosis. Acts a [...]
res2 protein networkhttps://string-db.org/network/284812.P41412Cell division cycle-related protein res2/pct1; Required for the initiation of mitotic and premeiotic DNA synthesis. Has an additional role in meiotic division.
bfr1 protein networkhttps://string-db.org/network/284812.P41820Brefeldin A resistance protein; Confers hyper-resistance to brefeldin A (BFA), an inhibitor of intracellular protein transport. Could serve as an efflux pump of various antibiotics; Belongs to th [...]
SPAC4A8.14 protein networkhttps://string-db.org/network/284812.P41831Ribose-phosphate pyrophosphokinase 1; 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phos [...]
rpt6 protein networkhttps://string-db.org/network/284812.P4183626S proteasome regulatory subunit 8 homolog; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency a [...]
rae1 protein networkhttps://string-db.org/network/284812.P41838Poly(A)+ RNA export protein; Required for mitotic cell growth as well as for spore germination. Functions in cell cycle progression through trafficking of proteins required for mitosis. Has a rol [...]
rpn11 protein networkhttps://string-db.org/network/284812.P4187826S proteasome regulatory subunit rpn11; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
hsp90 protein networkhttps://string-db.org/network/284812.P41887Heat shock protein 90 homolog; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle contr [...]
tnr3 protein networkhttps://string-db.org/network/284812.P41888Thiamine pyrophosphokinase; Involved in the regulation of thiamine metabolism, phosphate metabolism, mating and cell growth.
cut9 protein networkhttps://string-db.org/network/284812.P41889Anaphase-promoting complex subunit cut9; Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression throug [...]
scn3 protein networkhttps://string-db.org/network/284812.P41890Cut9-interacting protein scn1; Interacts with cut9.
gar2 protein networkhttps://string-db.org/network/284812.P41891Protein gar2; Helps the assembly of pre-ribosomal particles containing 18S rRNA; Belongs to the RRM GAR family.
cdc7 protein networkhttps://string-db.org/network/284812.P41892Cell division control protein 7; Protein kinase essential for cell division. Plays a key role in initiation of septum formation and cytokinesis.
stp1 protein networkhttps://string-db.org/network/284812.P41893Low molecular weight phosphotyrosine protein phosphatase; May contribute to dephosphorylation of 'Tyr-15' of cdc2; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
rad24 protein networkhttps://string-db.org/network/284812.P42656DNA damage checkpoint protein rad24; Required for the DNA damage checkpoint that ensures that DNA damage is repaired before mitosis is attempted. Acts as a negative regulator of meiosis by antago [...]
rad25 protein networkhttps://string-db.org/network/284812.P42657DNA damage checkpoint protein rad25; Required for the DNA damage checkpoint that ensures that DNA damage is repaired before mitosis is attempted.
gpt2 protein networkhttps://string-db.org/network/284812.P42881UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; Catalyzes the initial step in the synthesis of dolichol-P-P- oligosaccharides; Belongs to the glycosyltransferas [...]
ubc4 protein networkhttps://string-db.org/network/284812.P46595Ubiquitin-conjugating enzyme E2 4; Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Mediates ubiquitinati [...]
ptb1 protein networkhttps://string-db.org/network/284812.P46960Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to proteins having the C-terminal -XCC or -XCXC, where both c [...]
tif1 protein networkhttps://string-db.org/network/284812.P47943ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model [...]
trk1 protein networkhttps://string-db.org/network/284812.P47946Potassium transport protein 1; Together with TRK2, defines the major, high-affinity potassium influx transport system. Involved in maintenance of the proper sodium/potassium ratio in the cell and [...]
zfs1 protein networkhttps://string-db.org/network/284812.P47979Zinc finger protein zfs1; Binds to specific AU-rich elements (ARE) in the 3'- untranslated region of target mRNAs and promotes their degradation. Binds to ARE present in the arz1 mRNA and stimula [...]
pht1 protein networkhttps://string-db.org/network/284812.P48003Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require [...]
spn3 protein networkhttps://string-db.org/network/284812.P48008Septin homolog spn3; Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells.
spn4 protein networkhttps://string-db.org/network/284812.P48009Septin homolog spn4; Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells.
spn5 protein networkhttps://string-db.org/network/284812.P48010Septin homolog spn5; Septin-like protein involved in the correct orientation of forespore membrane extension during sporulation. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase [...]
rpc10 protein networkhttps://string-db.org/network/284812.P48011DNA-directed RNA polymerases I, II, and III subunit RPABC4; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Com [...]
sak1 protein networkhttps://string-db.org/network/284812.P48383Protein sak1; Positively regulates cyclic AMP-dependent protein kinase- mediated exit from the mitotic cell cycle; Belongs to the RFX family.
tfs1 protein networkhttps://string-db.org/network/284812.P49373Transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of tra [...]
mcm6 protein networkhttps://string-db.org/network/284812.P49731DNA replication licensing factor mcm6; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiat [...]
ndk1 protein networkhttps://string-db.org/network/284812.P49740Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, [...]
aph1 protein networkhttps://string-db.org/network/284812.P49776Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Asymmetrically hydrolyzes Ap4A to yield AMP and ATP.
cbp1 protein networkhttps://string-db.org/network/284812.P49777ARS-binding protein 1; Binds, preferentially, to the Maundrell ARS consensus sequence within ARS3002.
arg41 protein networkhttps://string-db.org/network/284812.P50514Probable argininosuccinate lyase.
vma3 protein networkhttps://string-db.org/network/284812.P50515V-type proton ATPase 16 kDa proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of [...]
hsp9 protein networkhttps://string-db.org/network/284812.P50519Heat shock protein hsp9.
pik3 protein networkhttps://string-db.org/network/284812.P50520Phosphatidylinositol 3-kinase vps34; Phosphatidylinositol 3-kinase homolog required for vacuolar sorting and segregation; Belongs to the PI3/PI4-kinase family.
hxk2 protein networkhttps://string-db.org/network/284812.P50521Hexokinase-2; Catalyzes the phosphorylation of hexose (six-carbon sugars) to hexose 6-phosphate. Phosphorylates D-glucose, D-fructose and D-mannose. Compared to hxk1, has a much higher affinity f [...]
qcr8 protein networkhttps://string-db.org/network/284812.P50523Cytochrome b-c1 complex subunit 8; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which dr [...]
rpn12 protein networkhttps://string-db.org/network/284812.P5052426S proteasome regulatory subunit rpn12; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
apn1 protein networkhttps://string-db.org/network/284812.P50525DNA-(apurinic or apyrimidinic site) lyase 1; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provide [...]
ssp1 protein networkhttps://string-db.org/network/284812.P50526Serine/threonine-protein kinase ssp1; Involved in actin localization and thus in polarized cell growth; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
shk1 protein networkhttps://string-db.org/network/284812.P50527Serine/threonine-protein kinase shk1/pak1; MAP4K component of the MAPK pathway required for the mating pheromone response. Phosphorylates histone H2B to form H2BS10ph (By similarity). Phosphoryla [...]
plo1 protein networkhttps://string-db.org/network/284812.P50528Serine/threonine-protein kinase plo1; Required to form a bipolar spindle, the actin ring and septum. Functions upstream of the whole septum formation pathway, including actin ring formation (regu [...]
sck1 protein networkhttps://string-db.org/network/284812.P50530Serine/threonine-protein kinase sck1; Protein kinase that is part of growth control pathway which is at least partially redundant with the cAMP pathway. Required for trehalase activation.
rad17 protein networkhttps://string-db.org/network/284812.P50531Checkpoint protein rad17; Participates in checkpoint pathways arrest of the cell cycle. A mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA syn [...]
mae1 protein networkhttps://string-db.org/network/284812.P50537Malic acid transport protein; Permease for malate and other C4 dicarboxylic acids; Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
hsk1 protein networkhttps://string-db.org/network/284812.P50582Cell cycle serine/threonine-protein kinase hsk1; Required for G1/S transition. Plays a role in DNA replication checkpoint signaling through regulating rad3 and cds1. Involved in the maintenance o [...]
ada1 protein networkhttps://string-db.org/network/284812.P50998AMP deaminase; AMP deaminase plays a critical role in energy metabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
cct4 protein networkhttps://string-db.org/network/284812.P50999T-complex protein 1 subunit delta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
rpl3001 protein networkhttps://string-db.org/network/284812.P5280860S ribosomal protein L30-1.
rpl501 protein networkhttps://string-db.org/network/284812.P5282260S ribosomal protein L5-A; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger R [...]
atf1 protein networkhttps://string-db.org/network/284812.P52890Transcription factor atf1; Transcription factor required for sexual development and entry into stationary phase. Binds and activates meiotic recombination hot spot ade6-M26.
smc6 protein networkhttps://string-db.org/network/284812.P53692Structural maintenance of chromosomes protein 6; Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ioni [...]
rds1 protein networkhttps://string-db.org/network/284812.P53693Protein rds1; May have a function in stress-related responses of the cell.
rtn1 protein networkhttps://string-db.org/network/284812.P53694Reticulon-like protein 1; Required for the correct positioning of the cellular division plane by delimiting the actomyosin ring assembly at the cell equator. Overexpression causes cell lysis.
exo1 protein networkhttps://string-db.org/network/284812.P53695Exodeoxyribonuclease 1; 5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs.
bem46 protein networkhttps://string-db.org/network/284812.P54069Protein bem46; Suppressor of bem1/bud5; Belongs to the serine esterase family.
pms1 protein networkhttps://string-db.org/network/284812.P54280DNA mismatch repair protein pms1; This protein is involved in the repair of mismatches in DNA.
orc1 protein networkhttps://string-db.org/network/284812.P54789Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcript [...]
hcs1 protein networkhttps://string-db.org/network/284812.P54874Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
ctt1 protein networkhttps://string-db.org/network/284812.P55306Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
tif11 protein networkhttps://string-db.org/network/284812.P55877Eukaryotic translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiato [...]
tif211 protein networkhttps://string-db.org/network/284812.P56286Eukaryotic translation initiation factor 2 subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a [...]
tif225 protein networkhttps://string-db.org/network/284812.P56287Probable translation initiation factor eIF-2B subunit epsilon; Subunit of the guanine nucleotide exchange factor for eIF-2. Belongs to the eIF-2B gamma/epsilon subunits family.
tif223 protein networkhttps://string-db.org/network/284812.P56288Probable translation initiation factor eIF-2B subunit gamma; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP.
tif51 protein networkhttps://string-db.org/network/284812.P56289Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of deca [...]
tif212 protein networkhttps://string-db.org/network/284812.P56329Probable eukaryotic translation initiation factor 2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex bi [...]
clr3 protein networkhttps://string-db.org/network/284812.P56523Histone deacetylase clr3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic [...]
rpl2801 protein networkhttps://string-db.org/network/284812.P5772860S ribosomal protein L28-B.
rps1901 protein networkhttps://string-db.org/network/284812.P5823440S ribosomal protein S19-A.
rpl3703 protein networkhttps://string-db.org/network/284812.P5928960S ribosomal protein L37-A; Binds to the 23S rRNA.
dad3 protein networkhttps://string-db.org/network/284812.P62505DASH complex subunit dad3; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates [...]
mrpl44 protein networkhttps://string-db.org/network/284812.P6250654S ribosomal protein L44, mitochondrial; Involved in mitochondrial genome encoded proteins translation.
utp18 protein networkhttps://string-db.org/network/284812.P78750Probable U3 small nucleolar RNA-associated protein 18; Involved in nucleolar processing of pre-18S ribosomal RNA.
asn1 protein networkhttps://string-db.org/network/284812.P78753Probable asparagine synthetase [glutamine-hydrolyzing].
par2 protein networkhttps://string-db.org/network/284812.P78759Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta 2 isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the [...]
qcr2 protein networkhttps://string-db.org/network/284812.P78761Cytochrome b-c1 complex subunit 2, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport [...]
yhm2 protein networkhttps://string-db.org/network/284812.P78763Uncharacterized mitochondrial carrier C83.13.
vti1 protein networkhttps://string-db.org/network/284812.P78768Vesicle transport v-SNARE protein vti1; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspe [...]
acs1 protein networkhttps://string-db.org/network/284812.P78773Probable acetyl-coenzyme A synthetase.
arc1 protein networkhttps://string-db.org/network/284812.P78774Actin-related protein 2/3 complex subunit 1; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promot [...]
SPCC1827.06c protein networkhttps://string-db.org/network/284812.P78780Probable aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs [...]
amk2 protein networkhttps://string-db.org/network/284812.P787895'-AMP-activated protein kinase subunit beta; Beta subunit of AMP-activated protein kinase (AMPK), which is required for transcriptional, metabolic, and developmental adaptations in response to g [...]
etf1 protein networkhttps://string-db.org/network/284812.P78790Probable electron transfer flavoprotein subunit alpha, mitochondrial; The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA [...]
cwf15 protein networkhttps://string-db.org/network/284812.P78794Pre-mRNA-splicing factor cwf15; Involved in pre-mRNA splicing.
tif307 protein networkhttps://string-db.org/network/284812.P78795Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a speciali [...]
pex7 protein networkhttps://string-db.org/network/284812.P78798Peroxisomal targeting signal 2 receptor; Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import.
gdh1 protein networkhttps://string-db.org/network/284812.P78804NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
vtc4 protein networkhttps://string-db.org/network/284812.P78810Vacuolar transporter chaperone 4; Component of the vacuolar transporter chaperone (VTC) complex, which plays a role in vacuolar membrane fusion.
fyu1 protein networkhttps://string-db.org/network/284812.P78811Probable UTP--glucose-1-phosphate uridylyltransferase; Plays a central role as a glucosyl donor in cellular metabolic pathways; Belongs to the UDPGP type 1 family.
gnd1 protein networkhttps://string-db.org/network/284812.P788126-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
ent3 protein networkhttps://string-db.org/network/284812.P78813ENTH domain-containing protein C794.11c.
srp2 protein networkhttps://string-db.org/network/284812.P78814Pre-mRNA-splicing factor srp2; Has a role in pre-mRNA splicing where it is involved in spliceosome assembly.
gmh5 protein networkhttps://string-db.org/network/284812.P78817Uncharacterized alpha-1,2-galactosyltransferase C637.06.
cut6 protein networkhttps://string-db.org/network/284812.P78820Acetyl-CoA carboxylase; Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
ado1 protein networkhttps://string-db.org/network/284812.P78825Adenosine kinase.
ilv5 protein networkhttps://string-db.org/network/284812.P78827Probable ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.
ght5 protein networkhttps://string-db.org/network/284812.P78831High-affinity glucose transporter ght5; High-affinity glucose transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
SPBC21B10.08c protein networkhttps://string-db.org/network/284812.P78833Uncharacterized protein C21B10.08c.
nup186 protein networkhttps://string-db.org/network/284812.P78847Nucleoporin nup186; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural component [...]
plb1 protein networkhttps://string-db.org/network/284812.P78854Lysophospholipase 1; Catalyzes the release of fatty acids from lysophospholipids. Required for survival under high osmolarity, for normal osmotic stress- induced gene expression, and for nutrient [...]
isa1 protein networkhttps://string-db.org/network/284812.P78859Iron-sulfur assembly protein 1; Involved in the assembly of mitochondrial and cytoplasmic iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly; Belon [...]
mrm2 protein networkhttps://string-db.org/network/284812.P78860rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of the 2'-O- methyluridine corresponding to position 2791 in [...]
fmd1 protein networkhttps://string-db.org/network/284812.P78870Probable S-(hydroxymethyl)glutathione dehydrogenase 1.
rst2 protein networkhttps://string-db.org/network/284812.P78871Zinc finger protein rst2; Key transcription factor for sexual development. Activates the transcription of ste11. Binds to a stress response element-like (SRE) region in the ste11 promoter.
tpp1 protein networkhttps://string-db.org/network/284812.P78875Trehalose-phosphatase; In the C-terminal section; belongs to the trehalose phosphatase family.
ddr48 protein networkhttps://string-db.org/network/284812.P78890Uncharacterized protein C23H3.15c.
SPBC16A3.12c protein networkhttps://string-db.org/network/284812.P78898Probable lipase C16A3.12c; Probable lipase; Belongs to the AB hydrolase superfamily. Lipase family.
pgi1 protein networkhttps://string-db.org/network/284812.P78917Glucose-6-phosphate isomerase.
nap2 protein networkhttps://string-db.org/network/284812.P78920Putative nucleosome assembly protein C2D10.11C.
cct8 protein networkhttps://string-db.org/network/284812.P78921Probable T-complex protein 1 subunit theta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By simil [...]
map1 protein networkhttps://string-db.org/network/284812.P78926Pheromone receptor transcription activator; In response to mating-pheromone signaling or nitrogen starvation, it interacts with mat1-Pc. This activates the expression of one of two mating-type-sp [...]
adf1 protein networkhttps://string-db.org/network/284812.P78929Cofilin; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. Binding to F-actin i [...]
sua1 protein networkhttps://string-db.org/network/284812.P78937Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role [...]
rpl26 protein networkhttps://string-db.org/network/284812.P7894660S ribosomal protein L26; Belongs to the universal ribosomal protein uL24 family.
mid1 protein networkhttps://string-db.org/network/284812.P78953Division mal foutue 1 protein; At the onset of mitosis, forms a medial ring structure before the arrangement of the medial actin ring. Essential for the central positioning of the division septum [...]
tif45 protein networkhttps://string-db.org/network/284812.P78954Eukaryotic translation initiation factor 4E-1; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome [...]
hus1 protein networkhttps://string-db.org/network/284812.P78955Checkpoint protein hus1; Essential in controlling the S-M checkpoint that couples mitosis to the completion of DNA replication. It is also required for the response to DNA damage.
tdh1 protein networkhttps://string-db.org/network/284812.P78958Glyceraldehyde-3-phosphate dehydrogenase 1; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
atf21 protein networkhttps://string-db.org/network/284812.P78962Transcription factor atf21.
skb1 protein networkhttps://string-db.org/network/284812.P78963Protein arginine N-methyltransferase skb1; S-adenosyl-L-methionine-dependent protein-arginine N- methyltransferase that can catalyze both the mono- and symmetric (type II) dimethylation of the gu [...]
pgr1 protein networkhttps://string-db.org/network/284812.P78965Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.
mam1 protein networkhttps://string-db.org/network/284812.P78966Mating factor M secretion protein mam1; Required in S.pombe M (minus) cells for production of M- factor pheromone. Involved in the transport of the farnesyl-derivation of the M-factor pheromone; [...]
pzh1 protein networkhttps://string-db.org/network/284812.P78968Serine/threonine-protein phosphatase PP-Z; Belongs to the PPP phosphatase family. PP-Z subfamily.
lag1 protein networkhttps://string-db.org/network/284812.P78970Sphingosine N-acyltransferase lag1; Component of the ceramide synthase complex required for C26- CoA-dependent ceramide synthesis. Facilitates ER-to-Golgi transport of GPI-anchored proteins (By s [...]
slp1 protein networkhttps://string-db.org/network/284812.P78972WD repeat-containing protein slp1; Required for mad2-dependent spindle checkpoint activation. Promotes ubiquitin-dependent degradation of cdc13 by the anaphase promoting complex/cyclosome (APC/C) [...]
hem2 protein networkhttps://string-db.org/network/284812.P78974Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes t [...]
taz1 protein networkhttps://string-db.org/network/284812.P79005Telomere length regulator taz1; Regulates telomere length and function. Required for the repression of telomere-adjacent gene expression and for normal meiosis or sporulation. It may be a negativ [...]
php5 protein networkhttps://string-db.org/network/284812.P79007Transcriptional activator hap5; Component of the CCAAT-bound heteromer, php5 is essential for DNA-binding activity. It is essential for transcription activation of cyc1. It is the linchpin that b [...]
rps2502 protein networkhttps://string-db.org/network/284812.P7900940S ribosomal protein S25-A.
cox4 protein networkhttps://string-db.org/network/284812.P79010Cytochrome c oxidase subunit 4, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The res [...]
tfa2 protein networkhttps://string-db.org/network/284812.P79011Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFI [...]
rpl3202 protein networkhttps://string-db.org/network/284812.P7901560S ribosomal protein L32-A; Belongs to the eukaryotic ribosomal protein eL32 family.
rps1902 protein networkhttps://string-db.org/network/284812.P7901640S ribosomal protein S19-B.
rhp16 protein networkhttps://string-db.org/network/284812.P79051ATP-dependent helicase rhp16; Involved in global genome repair (GGR) via nucleotide excision repair (NER), in conjunction with rhp7, after UV irradiation. Belongs to the SNF2/RAD54 helicase famil [...]
igo1 protein networkhttps://string-db.org/network/284812.P79058mRNA stability protein mug134; Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.
sui1 protein networkhttps://string-db.org/network/284812.P79060Protein translation factor sui1; Additional factor that functions in concert with eIF-2 and the initiator tRNA in directing the ribosome to the proper start site of translation.
erf1 protein networkhttps://string-db.org/network/284812.P79063Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
rad31 protein networkhttps://string-db.org/network/284812.P79064DNA damage tolerance protein rad31; Could be involved in a ubiquitin-related process important for DNA damage tolerance. Acts in a process which is defective in the checkpoint rad mutants and whi [...]
tip1 protein networkhttps://string-db.org/network/284812.P79065Tip elongation protein 1; Has a role in stabilizing and targeting the growing tips of the microtubules along the long axis of the cell, directing them to the ends of the cell. Acts as a cargo for [...]
rpl6 protein networkhttps://string-db.org/network/284812.P7907160S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family.
SPAC1002.07c protein networkhttps://string-db.org/network/284812.P79081N-acetyltransferase ats1; Belongs to the acetyltransferase family.
mgr2 protein networkhttps://string-db.org/network/284812.P79082Protein mgr2; Required for cell viability in cells lacking mitochondrial DNA; Belongs to the MGR2 family.
sum1 protein networkhttps://string-db.org/network/284812.P79083Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoi [...]
sec61 protein networkhttps://string-db.org/network/284812.P79088Protein transport protein sec61 subunit alpha; Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secr [...]
mam4 protein networkhttps://string-db.org/network/284812.P87014Protein-S-isoprenylcysteine O-methyltransferase; Mediates C-terminal methylation of the isoprenylated C- terminal cysteine in M-factor.
SPAC186.03 protein networkhttps://string-db.org/network/284812.P87015Probable L-asparaginase 1; Belongs to the asparaginase 1 family.
spg1 protein networkhttps://string-db.org/network/284812.P87027Septum-promoting GTP-binding protein 1; GTP-binding protein essential for the induction of septum formation at G2 and pre-START stages of mitosis. Acts via the cdc7 protein kinase pathway.
gms1 protein networkhttps://string-db.org/network/284812.P87041UDP-galactose transporter; Essential for the transport of UDP-galactose into the lumen of Golgi apparatus; Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
mts4 protein networkhttps://string-db.org/network/284812.P8704826S proteasome regulatory subunit rpn1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
pas1 protein networkhttps://string-db.org/network/284812.P87049G1/S-specific cyclin pas1; Essential for the control of the cell cycle at the G1/S (start) transition. Interacts with the pef1 protein kinase. The pef1/pas1 complex activates the res2/cdc10 compl [...]
cdr2 protein networkhttps://string-db.org/network/284812.P87050Mitosis inducer protein kinase cdr2; Acts as a mitotic inducer. In G2 it negatively regulates wee1, a mitotic inhibitor. Also has a role in cytokinesis where it required for proper septum formati [...]
cyp1 protein networkhttps://string-db.org/network/284812.P87051Peptidyl-prolyl cis-trans isomerase ppi1; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Be [...]
mug10 protein networkhttps://string-db.org/network/284812.P87052Meiotically up-regulated gene 10 protein; Has a role in meiosis.
pof1 protein networkhttps://string-db.org/network/284812.P87053F-box/WD repeat-containing protein pof1; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Required for the inactivation of zip1 via [...]
SPAC57A10.07 protein networkhttps://string-db.org/network/284812.P87055Uncharacterized protein C57A10.07.
SPAC57A10.08c protein networkhttps://string-db.org/network/284812.P87056Abhydrolase domain-containing protein C57A10.08c.
nhp6 protein networkhttps://string-db.org/network/284812.P87057Non-histone chromosomal protein 6; DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleos [...]
sla1 protein networkhttps://string-db.org/network/284812.P87058La protein homolog; Binds to the precursors of polymerase III RNAs. Functions in tRNA maturation.
mia40 protein networkhttps://string-db.org/network/284812.P87059Mitochondrial intermembrane space import and assembly protein 40; Required for the import and folding of small cysteine- containing proteins (small Tim) in the mitochondrial intermembrane space ( [...]
pop1 protein networkhttps://string-db.org/network/284812.P87060WD repeat-containing protein pop1; Involved in maintenance of ploidy through proteasome dependent degradation of CDK inhibitor rum1 and S-phase initiator cdc18. Functions as a recognition factor [...]
tea1 protein networkhttps://string-db.org/network/284812.P87061Tip elongation aberrant protein 1; Cell polarity protein. Acts as an end marker, directing the growth machinery to the cell poles. Involved in the regulation of microtubular organization, affecti [...]
crb2 protein networkhttps://string-db.org/network/284812.P87074DNA repair protein crb2; Essential for cell cycle arrest at the G1 and G2 stages following DNA damage by X-, and UV-irradiation, or inactivation of DNA ligase. Plays a role in the response to DNA [...]
itr2 protein networkhttps://string-db.org/network/284812.P87110Myo-inositol transporter 2; Transporter for myo-inositol.
SPAC20G8.04c protein networkhttps://string-db.org/network/284812.P87111Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Accepts electrons from ETF and reduces ubiquinone.
not1 protein networkhttps://string-db.org/network/284812.P87112General negative regulator of transcription subunit 1; Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the ma [...]
erg2 protein networkhttps://string-db.org/network/284812.P87113C-8 sterol isomerase erg2; Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols. Involved in the biosynthesis or ergosterol which is important for plasma membrane [...]
fft1 protein networkhttps://string-db.org/network/284812.P87114ATP-dependent helicase fft1; DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is required for heterochromatin organization.
nat10 protein networkhttps://string-db.org/network/284812.P87115RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) at positions 1297 and 1815 in [...]
atg6 protein networkhttps://string-db.org/network/284812.P87117Vacuolar protein sorting-associated protein atg6; Required for cytoplasm to vacuole transport (Cvt), autophagy, nucleophagy, and mitophagy, as a part of the autophagy-specific vps34 PI3-kinase co [...]
SPAC3A12.02 protein networkhttps://string-db.org/network/284812.P87118Putative inorganic pyrophosphatase C3A12.02.
meu34 protein networkhttps://string-db.org/network/284812.P87119RING finger protein mug145; Has a role in meiosis.
rpp1 protein networkhttps://string-db.org/network/284812.P87120Probable ribonuclease P protein subunit 3; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
taf2 protein networkhttps://string-db.org/network/284812.P87121Transcription initiation factor TFIID subunit 2; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA eleme [...]
SPAC3A12.06c protein networkhttps://string-db.org/network/284812.P87122Putative cation exchanger C3A12.06c; Putative cation exchanger; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
rpb11 protein networkhttps://string-db.org/network/284812.P87123DNA-directed RNA polymerase II subunit RPB11; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA [...]
ure4 protein networkhttps://string-db.org/network/284812.P87125Uncharacterized urease accessory protein ureD-like; Probably facilitates nickel incorporation; Belongs to the UreD family.
cwf2 protein networkhttps://string-db.org/network/284812.P87126Pre-mRNA-splicing factor cwf2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the [...]
atp11 protein networkhttps://string-db.org/network/284812.P87127Protein atp11, mitochondrial; Essential for the assembly of the mitochondrial F1-F0 complex. May interact with the alpha and/or beta subunits of F1-ATPase (By similarity); Belongs to the ATP11 fa [...]
tif310 protein networkhttps://string-db.org/network/284812.P87128Probable eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized [...]
vps53 protein networkhttps://string-db.org/network/284812.P87129Vacuolar protein sorting-associated protein 53; Involved in retrograde transport from early and late endosomes to late Golgi, leading to the membrane fusion between late Golgi and endosomal vesic [...]
tim17 protein networkhttps://string-db.org/network/284812.P87130Mitochondrial import inner membrane translocase subunit tim17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across th [...]
cys12 protein networkhttps://string-db.org/network/284812.P87131Cysteine synthase 2; Putative cysteine synthase that catalyzes the conversion of O-acetyl-L-serine (OAS) into cysteine, the last step in the cysteine biosynthesis pathway. However, in contrast to [...]
dbs2 protein networkhttps://string-db.org/network/284812.P87132Uncharacterized protein C167.05.
mug143 protein networkhttps://string-db.org/network/284812.P87133Meiotically up-regulated gene 143 protein; Has a role in meiosis.
SPAC57A7.05 protein networkhttps://string-db.org/network/284812.P87136Uncharacterized protein C57A7.05.
utp14 protein networkhttps://string-db.org/network/284812.P87137Uncharacterized protein C57A7.06.
SPAC57A7.07c protein networkhttps://string-db.org/network/284812.P87138Uncharacterized protein C57A7.07c.
SPAC57A7.09 protein networkhttps://string-db.org/network/284812.P87139Uncharacterized RING finger protein C57A7.09.
sec21 protein networkhttps://string-db.org/network/284812.P87140Probable coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediat [...]
mip1 protein networkhttps://string-db.org/network/284812.P87141Target of rapamycin complex 1 subunit mip1; Component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. Tor2 is essential for grow [...]
ssz1 protein networkhttps://string-db.org/network/284812.P87142Heat shock protein 70 homolog C57A7.12; Belongs to the heat shock protein 70 family.
rbm10 protein networkhttps://string-db.org/network/284812.P87143Uncharacterized RNA-binding protein C57A7.13.
trs1 protein networkhttps://string-db.org/network/284812.P87144Threonine--tRNA ligase, cytoplasmic; Belongs to the class-II aminoacyl-tRNA synthetase family.
vac14 protein networkhttps://string-db.org/network/284812.P87145Protein VAC14 homolog; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Regulates the synthesis of PtdIns(3,5)P [...]
tim22 protein networkhttps://string-db.org/network/284812.P87146Mitochondrial import inner membrane translocase subunit tim22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins [...]
egd2 protein networkhttps://string-db.org/network/284812.P87147Nascent polypeptide-associated complex subunit alpha; Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging poly [...]
hrf1 protein networkhttps://string-db.org/network/284812.P87148Protein transport protein yif1; Required for fusion of ER-derived vesicles with the Golgi during ER-to-Golgi protein transport. May be involved in proper membrane localization of Rab GTPases (By [...]
mrs2 protein networkhttps://string-db.org/network/284812.P87149Mitochondrial inner membrane magnesium transporter mrs2; High-conductance magnesium-selective channel that mediates the influx of magnesium into the mitochondrial matrix. Essential for the splici [...]
mic19 protein networkhttps://string-db.org/network/284812.P87150MICOS complex subunit mic19; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner mem [...]
tan1 protein networkhttps://string-db.org/network/284812.P87151Uncharacterized protein C25H2.10c.
spt7 protein networkhttps://string-db.org/network/284812.P87152Transcriptional activator spt7; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and SLIK. SAGA is involved in RNA polymerase II-dependent tr [...]
cct7 protein networkhttps://string-db.org/network/284812.P87153Probable T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similar [...]
cdc20 protein networkhttps://string-db.org/network/284812.P87154DNA polymerase epsilon catalytic subunit A; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
mug16 protein networkhttps://string-db.org/network/284812.P87155Protein GMH1 homolog; Has a role in meiosis; Belongs to the unc-50 family.
trs401 protein networkhttps://string-db.org/network/284812.P87156Probable 20S rRNA accumulation protein 4; Required for processing of the 20S pre-rRNA at site D to generate mature 18S rRNA; Belongs to the TSR4 family.
gga22 protein networkhttps://string-db.org/network/284812.P87157Probable ADP-ribosylation factor-binding protein C25H2.16c; May play a role in the regulation of membrane traffic through the trans-Golgi network; Belongs to the GGA protein family.
rps401 protein networkhttps://string-db.org/network/284812.P8715840S ribosomal protein S4-A; Belongs to the eukaryotic ribosomal protein eS4 family.
nif1 protein networkhttps://string-db.org/network/284812.P87159Mitosis inhibitor nif1; Functions as a negative regulator of mitosis. It interacts with the C-terminal of nim1, thereby inhibiting its kinase activity which phosphorylates wee1.
but2 protein networkhttps://string-db.org/network/284812.P87167Uba3-binding protein but2.
trz2 protein networkhttps://string-db.org/network/284812.P87168Ribonuclease Z 2, mitochondrial; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. May be involved in tRNA maturation, by removing a 3'-trailer from precursor [...]
mad1 protein networkhttps://string-db.org/network/284812.P87169Spindle assembly checkpoint component mad1; Central component of the spindle assembly checkpoint. Has a role in the correct positioning of the septum. Required for anchoring mad2 to the nuclear p [...]
ptp4 protein networkhttps://string-db.org/network/284812.P87170CTP-dependent diacylglycerol kinase 1; CTP-dependent diacylglycerol kinase that catalyzes the phosphorylation of diacylglycerol (DAG) to phosphatidate (PA). Controls phosphatidate levels at the n [...]
prs5 protein networkhttps://string-db.org/network/284812.P87171Ribose-phosphate pyrophosphokinase 5; 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phos [...]
gpi3 protein networkhttps://string-db.org/network/284812.P87172Phosphatidylinositol N-acetylglucosaminyltransferase gpi3 subunit; Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinos [...]
lsm1 protein networkhttps://string-db.org/network/284812.P87173U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by activating the decapping step. The LSM1-LSM7 complex binds RNA wi [...]
dpb4 protein networkhttps://string-db.org/network/284812.P87174DNA polymerase epsilon subunit D; As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication. It is required during synthesis of the lead [...]
apn2 protein networkhttps://string-db.org/network/284812.P87175DNA-(apurinic or apyrimidinic site) lyase 2; DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provide [...]
slx8 protein networkhttps://string-db.org/network/284812.P87176E3 ubiquitin-protein ligase complex slx8-rfp subunit slx8; Mediates ubiquitination and subsequent desumoylation/degradation of sumoylated proteins and proteins containing SUMO-like domains. Acts [...]
dip2 protein networkhttps://string-db.org/network/284812.P87177Uncharacterized WD repeat-containing protein C3D6.12; Belongs to the WD repeat WDR3/UTP12 family.
pdi3 protein networkhttps://string-db.org/network/284812.P87178Uncharacterized protein C3D6.13c.
wsc1 protein networkhttps://string-db.org/network/284812.P87179Cell wall integrity and stress response component 1.
hem4 protein networkhttps://string-db.org/network/284812.P87214Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
dim1 protein networkhttps://string-db.org/network/284812.P87215Mitosis protein dim1; Plays a fundamental role as a protein essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis. May play a role in mitotic sp [...]
vip1 protein networkhttps://string-db.org/network/284812.P87216Protein vip1.
mis6 protein networkhttps://string-db.org/network/284812.P87227Inner kinetochore subunit mis6; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segre [...]
ser3 protein networkhttps://string-db.org/network/284812.P87228Putative D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pat [...]
SPCC4G3.03 protein networkhttps://string-db.org/network/284812.P87229Uncharacterized protein C4G3.03.
coq5 protein networkhttps://string-db.org/network/284812.P872302-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-meth [...]
mus81 protein networkhttps://string-db.org/network/284812.P87231Crossover junction endonuclease mus81; Interacts with eme1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Ty [...]
mrpl4 protein networkhttps://string-db.org/network/284812.P8723254S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL29 family.
phf1 protein networkhttps://string-db.org/network/284812.P87233SWM histone demethylase complex subunit phf1; Component of the SWM histone demethylase complex that specifically demethylates H3K9me2, a specific tag for epigenetic transcriptional activation, th [...]
gyp3 protein networkhttps://string-db.org/network/284812.P87234GTPase-activating protein gyp3; Regulates exocytosis by functioning as a GAP for ypt2.
rhp42 protein networkhttps://string-db.org/network/284812.P87235DNA repair protein rhp42; Has a role in the nucleotide excision repair (NER) pathway. Acts in both transcription-coupled repair (TCR) which removes damage from the transcribed strand of active ge [...]
nur1 protein networkhttps://string-db.org/network/284812.P87236Meiotically up-regulated gene 154 protein; Has a role in meiosis.
SPCC4G3.12c protein networkhttps://string-db.org/network/284812.P87237Uncharacterized RING finger protein C4G3.12c.
cue1 protein networkhttps://string-db.org/network/284812.P87238CUE domain-containing protein 4, mitochondrial.
mdj1 protein networkhttps://string-db.org/network/284812.P87239DnaJ homolog 1, mitochondrial.
not2 protein networkhttps://string-db.org/network/284812.P87240General negative regulator of transcription subunit 2; Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the ma [...]
rib2 protein networkhttps://string-db.org/network/284812.P87241Diaminohydroxyphosphoribosylamino-pyrimidine deaminase; Involved in riboflavin biosynthesis. Converts 2,5-diamino-6- (ribosylamino)-4(3H)-pyrimidinone 5'-phosphate into 5-amino-6- (ribosylamino)- [...]
hdd1 protein networkhttps://string-db.org/network/284812.P87242HD domain-containing protein C4G3.17.
rix1 protein networkhttps://string-db.org/network/284812.P87243Pre-rRNA-processing protein rix1; Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre- 60S ribosomal subunits. Regul [...]
alp16 protein networkhttps://string-db.org/network/284812.P87244Spindle pole body component alp16; Component of the gamma tubule complex that is required for the regulation of both interphase microtubules and mitotic bipolar spindles.
kms1 protein networkhttps://string-db.org/network/284812.P87245Karyogamy meiotic segregation protein 1; Has a role in karyogamy, recombination and segregation during meiosis. Although it has been shown to associate with the spindle pole body it is unlikely t [...]
sub1 protein networkhttps://string-db.org/network/284812.P87294Putative RNA polymerase II transcriptional coactivator; General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general [...]
SPAC16A10.03c protein networkhttps://string-db.org/network/284812.P87295Pep5-like zinc finger protein C16A10.03c.
dad1 protein networkhttps://string-db.org/network/284812.P87297DASH complex subunit dad1; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates [...]
tfb2 protein networkhttps://string-db.org/network/284812.P87303General transcription and DNA repair factor IIH subunit tfb2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription [...]
the13 protein networkhttps://string-db.org/network/284812.P87304Putative esterase C31F10.02; Belongs to the thioesterase PaaI family.
ggg1 protein networkhttps://string-db.org/network/284812.P87305Glutathione-specific gamma-glutamylcyclotransferase; Gamma-glutamylcyclotransferase acting specifically on glutathione, but not on other gamma-glutamyl peptides. Allows utilization of gluthathion [...]
srb4 protein networkhttps://string-db.org/network/284812.P87306Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
mug37 protein networkhttps://string-db.org/network/284812.P87307Meiotically up-regulated gene 37 protein; Has a role in meiosis.
lsb5 protein networkhttps://string-db.org/network/284812.P87308Protein lsb5; Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking; Belongs to the LSB5 family.
mde2 protein networkhttps://string-db.org/network/284812.P87309Mei4-dependent protein 2; Required for the formation of meiotic double-strand breaks and for the segregation of homologous centromeres during meiosis I. Interacts with the SFT and DSBC complexes, [...]
nut2 protein networkhttps://string-db.org/network/284812.P87310Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
mub1 protein networkhttps://string-db.org/network/284812.P87311MYND-type zinc finger protein C31F10.10c.
cwf4 protein networkhttps://string-db.org/network/284812.P87312Pre-mRNA-splicing factor cwf4; Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity); Belongs to th [...]
tma20 protein networkhttps://string-db.org/network/284812.P87313Translation machinery-associated protein 20; Involved in translation.
hip1 protein networkhttps://string-db.org/network/284812.P87314Protein hir1; Probably required for replication-independent chromatin assembly. Required for transcriptional silencing in the outer repeat (otr) centromeric repeats and the Tf2 long terminal repe [...]
hip3 protein networkhttps://string-db.org/network/284812.P87315Histone transcription regulator 3 homolog; Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation. Required for transc [...]
atp15 protein networkhttps://string-db.org/network/284812.P87316Putative ATP synthase subunit epsilon, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across th [...]
bch1 protein networkhttps://string-db.org/network/284812.P87317Uncharacterized protein C31F10.16.
SPBC31F10.17c protein networkhttps://string-db.org/network/284812.P87318Uncharacterized protein C31F10.17c.
vps1301 protein networkhttps://string-db.org/network/284812.P87319Vacuolar protein sorting-associated protein 13a; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family.
msp1 protein networkhttps://string-db.org/network/284812.P87320Protein msp1, mitochondrial; Dynamin-related GTPase required for mitochondrial fusion. Coordinates interaction between the inner and outer mitochondrial membrane to promote the formation of the d [...]
mcs4 protein networkhttps://string-db.org/network/284812.P87323Response regulator mcs4; Response regulator that coordinately controls the stress activated wak1-wis1-sty1 MAP kinase pathway and fission yeast cell cycle.
cdc1 protein networkhttps://string-db.org/network/284812.P87324DNA polymerase subunit delta-2; Required for replication of the leading DNA strand and for completion of lagging strand synthesis. It is essential for cell cycle progression.
pho2 protein networkhttps://string-db.org/network/284812.Q004724-nitrophenylphosphatase.
mam2 protein networkhttps://string-db.org/network/284812.Q00619Pheromone P-factor receptor; Receptor for the peptide pheromone P-factor, a mating factor of S.pombe. Pheromone signaling is essential for initiation of meiosis in S.pombe; P-factor signaling alo [...]
cdc42 protein networkhttps://string-db.org/network/284812.Q01112Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
sar1 protein networkhttps://string-db.org/network/284812.Q01475Small COPII coat GTPase sar1; Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has tw [...]
pap1 protein networkhttps://string-db.org/network/284812.Q01663AP-1-like transcription factor; Transcription activator involved in multidrug resistance, oxidative stress response, and redox homeostasis. Regulates the transcription of genes encoding antioxida [...]
pho4 protein networkhttps://string-db.org/network/284812.Q01682Thiamine-repressible acid phosphatase pho4; May dephosphorylate thiamine phosphates; Belongs to the histidine acid phosphatase family.
rpb2 protein networkhttps://string-db.org/network/284812.Q02061DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest com [...]
cdc8 protein networkhttps://string-db.org/network/284812.Q02088Tropomyosin; Forms part of the F-actin contractile ring during cytokinesis.
rad3 protein networkhttps://string-db.org/network/284812.Q02099Protein kinase rad3; Serine/threonine kinase which activates checkpoint signaling upon genotoxic stresses. Involved in G2 arrest following DNA damage where it phosphorylates chk1. Phosphorylation [...]
hmt1 protein networkhttps://string-db.org/network/284812.Q02592Heavy metal tolerance protein; Involved in metal tolerance. Probably involved in the transport of metal-bound phytochelatins. Compartmentalizes cadmium within vacuoles, thereby protecting cells f [...]
ade2 protein networkhttps://string-db.org/network/284812.Q02787Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of [...]
hsf1 protein networkhttps://string-db.org/network/284812.Q02953Heat shock factor protein; DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. Also required for growth at normal temperatures.
prh1 protein networkhttps://string-db.org/network/284812.Q03319Probable ATP-dependent RNA helicase prh1; May be involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily.
pcn1 protein networkhttps://string-db.org/network/284812.Q03392Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's proces [...]
esc1 protein networkhttps://string-db.org/network/284812.Q04635Protein esc1; Involved in the sexual differentiation process. Modulate the ability of the cell to differentiate in response to the nitrogen starvation signal; in particular in response to decreas [...]
gpa2 protein networkhttps://string-db.org/network/284812.Q04665Guanine nucleotide-binding protein alpha-2 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. This pro [...]
frp1 protein networkhttps://string-db.org/network/284812.Q04800Ferric reductase transmembrane component 1; Metalloreductase responsible for reducing extracellular iron and copper prior to import (By similarity). Catalyzes the reductive uptake of Fe(3+)-salts [...]
swi10 protein networkhttps://string-db.org/network/284812.Q06182Mating-type switching protein swi10; Involved in termination of copy-synthesis during mating-type switching. Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or [...]
gar1 protein networkhttps://string-db.org/network/284812.Q06975H/ACA ribonucleoprotein complex subunit gar1; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for [...]
prp4 protein networkhttps://string-db.org/network/284812.Q07538Serine/threonine-protein kinase prp4; Has a role in pre-mRNA splicing and is essential for growth. Phosphorylates srp1.
eri1 protein networkhttps://string-db.org/network/284812.Q08I433'-5' exonuclease eri1; RNA exonuclease that acts as a negative regulator of RNA interference (RNAi). Acts by degrading the 3'-overhangs of double- stranded short interfering RNAs (siRNAs). Repre [...]
rec15 protein networkhttps://string-db.org/network/284812.Q09094Meiotic recombination protein rec15; Required during the early stages of meiosis for meiotic recombination. Involved in chromosome segregation where it is required for separation of sister chroma [...]
rnp24 protein networkhttps://string-db.org/network/284812.Q09100RNA-binding protein rnp24.
spn2 protein networkhttps://string-db.org/network/284812.Q09116Septin homolog spn2; Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells. Involved in the correct orientation of forespore [...]
rpl1001 protein networkhttps://string-db.org/network/284812.Q0912760S ribosomal protein L10-A.
tif213 protein networkhttps://string-db.org/network/284812.Q09130Eukaryotic translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a [...]
gpt1 protein networkhttps://string-db.org/network/284812.Q09140UDP-glucose:glycoprotein glucosyltransferase; Selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER. Unfolded, denatured glycoprote [...]
orc2 protein networkhttps://string-db.org/network/284812.Q09142Origin recognition complex subunit 2; Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcript [...]
hba1 protein networkhttps://string-db.org/network/284812.Q09146Brefeldin A resistance protein.
rec14 protein networkhttps://string-db.org/network/284812.Q09150Meiotic recombination protein rec14; Required for formation of the rec12-mediated double-strand breaks (DSBs) that initiate meiotic recombination.
rip1 protein networkhttps://string-db.org/network/284812.Q09154Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron tran [...]
cds1 protein networkhttps://string-db.org/network/284812.Q09170Serine/threonine-protein kinase cds1; Has a role in the DNA replication-monitoring S/G2 checkpoint system. It is responsible for blocking mitosis in the S phase. It monitors DNA synthesis by inte [...]
pdb1 protein networkhttps://string-db.org/network/284812.Q09171Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copi [...]
ptc2 protein networkhttps://string-db.org/network/284812.Q09172Protein phosphatase 2C homolog 2; Has an important role in osmotic stability and cell shape control. It may negatively regulate the osmosensing signal transmitted through wis1 map kinase.
ptc3 protein networkhttps://string-db.org/network/284812.Q09173Protein phosphatase 2C homolog 3; Has an important role in osmotic stability and cell shape control. It may negatively regulate the osmosensing signal transmitted through wis1 map kinase.
gma12 protein networkhttps://string-db.org/network/284812.Q09174Alpha-1,2-galactosyltransferase; Involved in the O- and N-linked oligosaccharide modification of proteins transported through the Golgi stack. This occurs in cis Golgi where the enzyme transfers [...]
krp1 protein networkhttps://string-db.org/network/284812.Q09175Dibasic-processing endoprotease; Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins. Essential for cell viability. Cleaves substrat [...]
uaf2 protein networkhttps://string-db.org/network/284812.Q09176Splicing factor U2AF 23 kDa subunit; Necessary for the splicing of pre-mRNA. The SF1-U2AF59-U2AF23 complex has a role in the recognition of the branch site (5'-UACUAAC- 3'), the pyrimidine tract [...]
rpc19 protein networkhttps://string-db.org/network/284812.Q09177DNA-directed RNA polymerases I and III subunit RPAC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common co [...]
gln1 protein networkhttps://string-db.org/network/284812.Q09179Glutamine synthetase.
map2 protein networkhttps://string-db.org/network/284812.Q09180P-factor-like 1; In h- cells under nutritional starvation, P-factor induces alteration of cell morphology toward mating, arrest of the cell cycle at the G1 phase prior to the initiation of DNA sy [...]
ste13 protein networkhttps://string-db.org/network/284812.Q09181Putative ATP-dependent RNA helicase ste13; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping. Is involved in G1/S DNA-damage checkpoint recovery, proba [...]
cdb4 protein networkhttps://string-db.org/network/284812.Q09184Curved DNA-binding protein; A non-essential protein that preferentially binds curved DNA. Binds non-curved DNA with a much lower affinity; Belongs to the peptidase M24 family.
anc1 protein networkhttps://string-db.org/network/284812.Q09188ADP,ATP carrier protein; Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane; Belongs to the mitochondrial carrier (TC 2.A.29) family.
azr1 protein networkhttps://string-db.org/network/284812.Q091895-azacytidine resistance protein azr1; Confers azacytidine resistance in high copy.
cdd1 protein networkhttps://string-db.org/network/284812.Q09190Putative cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
rpb5 protein networkhttps://string-db.org/network/284812.Q09191DNA-directed RNA polymerases I, II, and III subunit RPABC1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Com [...]
erg24 protein networkhttps://string-db.org/network/284812.Q09195Delta(14)-sterol reductase; Reduces the C14=C15 double bond of 4,4-dimethyl-cholesta- 8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol. Belongs to the ERG4/ERG24 family.
cdc4 protein networkhttps://string-db.org/network/284812.Q09196Myosin regulatory light chain cdc4; Involved in cytokinesis. Required for the formation and function of the contractile ring.
mlo2 protein networkhttps://string-db.org/network/284812.Q09329Protein mlo2; Not known, interfere with mitotic chromosome segregation when overexpressed.
mlo3 protein networkhttps://string-db.org/network/284812.Q09330mRNA export protein mlo3; Has a role in the mRNA export process. Interferes with mitotic chromosome segregation when overexpressed.
rpl22 protein networkhttps://string-db.org/network/284812.Q0966860S ribosomal protein L22; Belongs to the eukaryotic ribosomal protein eL22 family.
adh4 protein networkhttps://string-db.org/network/284812.Q09669Alcohol dehydrogenase 4; Involved in ethanol oxidation in mitochondria. Belongs to the iron-containing alcohol dehydrogenase family.
SPAC5H10.04 protein networkhttps://string-db.org/network/284812.Q09670Putative NADPH dehydrogenase C5H10.04.
SPAC5H10.10 protein networkhttps://string-db.org/network/284812.Q09671Putative NADPH dehydrogenase C5H10.10.
ecm31 protein networkhttps://string-db.org/network/284812.Q09672Probable 3-methyl-2-oxobutanoate hydroxymethyltransferase; Belongs to the PanB family.
pan6 protein networkhttps://string-db.org/network/284812.Q09673Pantoate--beta-alanine ligase; Belongs to the pantothenate synthetase family.
dgc1 protein networkhttps://string-db.org/network/284812.Q09674Putative hydro-lyase C5H10.01; Belongs to the D-glutamate cyclase family.
hsp3102 protein networkhttps://string-db.org/network/284812.Q09675Glutathione-independent glyoxalase hsp3102; Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step. May play a role in detoxifying endogenously [...]
gmh1 protein networkhttps://string-db.org/network/284812.Q09679Probable alpha-1,2-galactosyltransferase gmh1.
otg1 protein networkhttps://string-db.org/network/284812.Q09680Uncharacterized protein C5H10.12c.
gmh2 protein networkhttps://string-db.org/network/284812.Q09681Probable alpha-1,2-galactosyltransferase gmh2.
pre9 protein networkhttps://string-db.org/network/284812.Q09682Probable proteasome subunit alpha type-3; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent [...]
mre11 protein networkhttps://string-db.org/network/284812.Q09683DNA repair protein rad32; Required for the repair of double strand breaks (DSB) caused by gamma and UV radiation. May work in conjunction with rhp51; Belongs to the MRE11/RAD32 family.
tht1 protein networkhttps://string-db.org/network/284812.Q09684Nuclear fusion protein tht1; Required for nuclear membrane fusion during karyogamy. Belongs to the KAR5 family.
dre4 protein networkhttps://string-db.org/network/284812.Q09685Pre-mRNA-splicing factor dre4; Component of the spliceosome involved in mRNA processing.
SPAC13C5.04 protein networkhttps://string-db.org/network/284812.Q09686Putative glutamine amidotransferase-like protein C13C5.04.
SPAC13C5.05c protein networkhttps://string-db.org/network/284812.Q09687Phosphoacetylglucosamine mutase 1; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and a [...]
tif5 protein networkhttps://string-db.org/network/284812.Q09689Probable eukaryotic translation initiation factor 5; Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of [...]
pom1 protein networkhttps://string-db.org/network/284812.Q09690DYRK-family kinase pom1; Polarity factor involved in localization of polarized growth and cytokinesis. Forms an intracellular gradient that serves to measure cell length and control mitotic entry [...]
mrf1 protein networkhttps://string-db.org/network/284812.Q09691Putative peptide chain release factor 1, mitochondrial; Belongs to the prokaryotic/mitochondrial release factor family.
wrs1 protein networkhttps://string-db.org/network/284812.Q09692Tryptophan--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
pol4 protein networkhttps://string-db.org/network/284812.Q09693DNA polymerase type-X family protein pol4; Repair polymerase. Involved in gap-filling in DNA non- homologous end joining (NHEJ) required for double-strand break repair. Can incorporate a ribonucl [...]
lys3 protein networkhttps://string-db.org/network/284812.Q09694Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Catalyzes the NAD(+)-dependent cleavage of saccharopine to L- lysine and 2-oxoglutarate, the final step in the alpha-aminoadipate (AAA) path [...]
psr1 protein networkhttps://string-db.org/network/284812.Q09695Uncharacterized protein C2F7.02c.
med1 protein networkhttps://string-db.org/network/284812.Q09696Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Me [...]
rga8 protein networkhttps://string-db.org/network/284812.Q09697Rho-GTPase-activating protein 8; Acts in signal transduction. Negatively regulates the pak1/shk1 control pathway.
cph2 protein networkhttps://string-db.org/network/284812.Q09698Uncharacterized protein C2F7.07c.
snf5 protein networkhttps://string-db.org/network/284812.Q09699SWI/SNF chromatin-remodeling complex subunit snf5; Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expre [...]
gep3 protein networkhttps://string-db.org/network/284812.Q09700Uncharacterized protein C2F7.09c.
akr1 protein networkhttps://string-db.org/network/284812.Q09701Palmitoyltransferase akr1; Palmitoyltransferase specific for casein kinase 1. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
nrd1 protein networkhttps://string-db.org/network/284812.Q09702Negative regulator of differentiation 1; Negative regulator of sexual differentiation. Acts by repressing the transcription of meiosis-inducing, ste11-regulated genes until cells reach a critical [...]
rrp4 protein networkhttps://string-db.org/network/284812.Q09704Exosome complex component rrp4; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrada [...]
rsm24 protein networkhttps://string-db.org/network/284812.Q0970537S ribosomal protein S24, mitochondrial; Involved in mitochondrial genome encoded proteins translation.
pld1 protein networkhttps://string-db.org/network/284812.Q09706Phospholipase D1; Required for meiosis and spore formation. Seems to be involved in the coordinate induction of late meiotic events.
SPAC18B11.09c protein networkhttps://string-db.org/network/284812.Q09707Putative acetyltransferase C18B11.09c; Belongs to the transferase hexapeptide repeat family.
SPAC12G12.16c protein networkhttps://string-db.org/network/284812.Q09708Uncharacterized protein C12G12.16c.
pus9 protein networkhttps://string-db.org/network/284812.Q09709Uncharacterized protein C18B11.02c; Belongs to the pseudouridine synthase RluA family.
SPAC18B11.03c protein networkhttps://string-db.org/network/284812.Q09710Uncharacterized protein C18B11.03c.
ncs1 protein networkhttps://string-db.org/network/284812.Q09711Calcium-binding protein NCS-1; Negatively regulates sporulation perhaps by controlling Ca(2+)-dependent desensitization of git3.
gpi18 protein networkhttps://string-db.org/network/284812.Q09712GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Responsible for the transfer of the second mannose to the glycosylphosphatidylinosito [...]
lcp5 protein networkhttps://string-db.org/network/284812.Q09713Uncharacterized protein C18B11.06.
pat10 protein networkhttps://string-db.org/network/284812.Q09714Uncharacterized protein C18B11.08c.
tup11 protein networkhttps://string-db.org/network/284812.Q09715Transcriptional repressor tup11; Transcriptional repressor.
SPAC18B11.11 protein networkhttps://string-db.org/network/284812.Q09716Uncharacterized protein C18B11.11.
sbp1 protein networkhttps://string-db.org/network/284812.Q09717Ran-specific GTPase-activating protein 1; Stimulates the GTPase activity in the presence of RNA1. May potentiate the action of RanGAP1 (RNA1), thus playing the role of a negative regulator; Belon [...]
apm4 protein networkhttps://string-db.org/network/284812.Q09718AP-2 complex subunit mu; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmi [...]
dbp10 protein networkhttps://string-db.org/network/284812.Q09719ATP-dependent RNA helicase dbp10; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD [...]
pre1 protein networkhttps://string-db.org/network/284812.Q09720Probable proteasome subunit beta type-4; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent t [...]
tif313 protein networkhttps://string-db.org/network/284812.Q09722Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoi [...]
trm112 protein networkhttps://string-db.org/network/284812.Q09723Multifunctional methyltransferase subunit trm112; Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase mtq2, required for the methylation of eRF1 [...]
mrp11 protein networkhttps://string-db.org/network/284812.Q0972454S ribosomal protein L11, mitochondrial; Involved in mitochondrial genome encoded proteins translation.
mis4 protein networkhttps://string-db.org/network/284812.Q09725Sister chromatid cohesion protein mis4; Plays a structural role in chromatin. Chromatid cohesion molecule required for equal sister chromatid separation in anaphase. May form a stable link betwee [...]
atp25 protein networkhttps://string-db.org/network/284812.Q09726ATPase synthesis protein 25, mitochondrial; mRNA stabilization factor specific for the 0.95 kb oli1 mRNA. Also involved in oli1 ring formation (By similarity); Belongs to the ATP25 family.
mrp20 protein networkhttps://string-db.org/network/284812.Q0972754S ribosomal protein L23, mitochondrial; Involved in mitochondrial genome encoded proteins translation.
cuf1 protein networkhttps://string-db.org/network/284812.Q09728Metal-binding regulatory protein cuf1; Copper-sensing transcription factor that regulates iron uptake genes. Under copper starvation conditions activates the transcription of the copper transport [...]
rod1 protein networkhttps://string-db.org/network/284812.Q09729Arrestin domain-containing protein C31A2.12.
sft1 protein networkhttps://string-db.org/network/284812.Q09730Protein transport protein sft1; Vesicle SNARE required for retrograde transport within the Golgi complex.
bun107 protein networkhttps://string-db.org/network/284812.Q09731UBP9-binding protein bun107; Required for the ubp9 recruitment to septa and cell tips but also for its enzymatic activity at these specific locations.
dcc1 protein networkhttps://string-db.org/network/284812.Q09732Sister chromatid cohesion protein dcc1; Essential for the fidelity of chromosome transmission. Required for the DNA replication block checkpoint. Replication factor C (RFC) complex has an essenti [...]
gef2 protein networkhttps://string-db.org/network/284812.Q09733Rho guanine nucleotide exchange factor gef2; Has a role in the control of cell polarity and cytokinesis. Involved in bipolar growth and septum formation.
ysp2 protein networkhttps://string-db.org/network/284812.Q09735Putative aminopeptidase C13A11.05; Belongs to the peptidase M17 family.
erg11 protein networkhttps://string-db.org/network/284812.Q09736Lanosterol 14-alpha demethylase erg11; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-trien [...]
pdc202 protein networkhttps://string-db.org/network/284812.Q09737Putative pyruvate decarboxylase C13A11.06; Belongs to the TPP enzyme family.
ubp8 protein networkhttps://string-db.org/network/284812.Q09738Probable ubiquitin carboxyl-terminal hydrolase 8.
mcp7 protein networkhttps://string-db.org/network/284812.Q09739Meiotic coiled-coil protein 7; Required for meiotic recombination.
gfa1 protein networkhttps://string-db.org/network/284812.Q09740Probable glutamine--fructose-6-phosphate aminotransferase [isomerizing]; Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of [...]
srm1 protein networkhttps://string-db.org/network/284812.Q09741Spermidine synthase; Belongs to the spermidine/spermine synthase family.
ste20 protein networkhttps://string-db.org/network/284812.Q09743Target of rapamycin complex 2 subunit ste20; Component of TORC2, which regulates multiple cellular processes to control cell growth in response to environmental signals. TORC2 is required for cel [...]
SPBC12C2.03c protein networkhttps://string-db.org/network/284812.Q09744Uncharacterized FAD-binding protein C12C2.03c.
SPBC12C2.04 protein networkhttps://string-db.org/network/284812.Q09745Uncharacterized protein C12C2.04; To S.pombe SpAC2E11.17.
bzz1 protein networkhttps://string-db.org/network/284812.Q09746Protein BZZ1; Plays a role in endocytosis and trafficking to the vacuole. Functions with type I myosins to restore polarity of the actin cytoskeleton after NaCl stress (By similarity); Belongs to [...]
dbp5 protein networkhttps://string-db.org/network/284812.Q09747ATP-dependent RNA helicase dbp5; ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA exp [...]
dnm1 protein networkhttps://string-db.org/network/284812.Q09748Dynamin-related protein dnm1; Microtubule-associated force-producing protein that mediates mitochondrial fission during interphasic growth and at cell division. Fission of mitochondria occurs in [...]
izh2 protein networkhttps://string-db.org/network/284812.Q09749ADIPOR-like receptor SPBC12C2.09c; Probable receptor, which may be involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Belongs to the ADIPOR family.
pst1 protein networkhttps://string-db.org/network/284812.Q09750Paired amphipathic helix protein pst1; Has a role in modulating the nuclear import of TF1 virus-like particles. Essential for viability.
glo1 protein networkhttps://string-db.org/network/284812.Q09751Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
fnx1 protein networkhttps://string-db.org/network/284812.Q09752Multidrug resistance protein fnx1; Efflux transporter. Confers resistance to a variety of toxic compounds.
SPAC24H6.10c protein networkhttps://string-db.org/network/284812.Q09755Putative phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7- [...]
hxk1 protein networkhttps://string-db.org/network/284812.Q09756Hexokinase-1; Catalyzes the phosphorylation of hexose (six-carbon sugars) to hexose 6-phosphate. Phosphorylates D-fructose, D-mannose and, to a lower extent, D-glucose. Compared to hxk2, has low [...]
rps901 protein networkhttps://string-db.org/network/284812.Q0975740S ribosomal protein S9-A; Belongs to the universal ribosomal protein uS4 family.
gup1 protein networkhttps://string-db.org/network/284812.Q09758Putative membrane-bound O-acyltransferase C24H6.01c.
tim15 protein networkhttps://string-db.org/network/284812.Q09759Uncharacterized protein C24H6.02c.
cul3 protein networkhttps://string-db.org/network/284812.Q09760Cullin-3; Probable core component of multiple cullin-RING-based BC3B (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation o [...]
sld3 protein networkhttps://string-db.org/network/284812.Q09761DNA replication regulator sld3; Required for loading and maintenance of stable association of cdc45 with chromatin during initiation and elongation of DNA replication. Also involved in temporal r [...]
gef1 protein networkhttps://string-db.org/network/284812.Q09763Rho guanine nucleotide exchange factor gef1; Has a role in the control of cell polarity and cytokinesis. Involved in bipolar growth, via modulation of cdc42-shk1-orb6 signaling, and septum format [...]
SPAC24H6.11c protein networkhttps://string-db.org/network/284812.Q09764Uncharacterized protein C24H6.11c.
uba3 protein networkhttps://string-db.org/network/284812.Q09765NEDD8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric uba3-ula1 E1 enzyme. E1 activates NEDD8/ubl1 by first adenylating its C-terminal glycine residue with ATP, thereafte [...]
SPAC24H6.13 protein networkhttps://string-db.org/network/284812.Q09766Uncharacterized membrane protein C24H6.13; Acts as an osmosensitive calcium-permeable cation channel. Belongs to the CSC1 (TC 1.A.17) family.
alp41 protein networkhttps://string-db.org/network/284812.Q09767ADP-ribosylation factor-like protein alp41; Has a role in the cofactor-dependent pathway of microtubule biogenesis. Required for growth polarity control. Belongs to the small GTPase superfamily. [...]
gcs1 protein networkhttps://string-db.org/network/284812.Q09768Glutamate--cysteine ligase.
lon1 protein networkhttps://string-db.org/network/284812.Q09769Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-l [...]
SPAC1296.01c protein networkhttps://string-db.org/network/284812.Q09770Phosphoacetylglucosamine mutase 2; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and a [...]
atf31 protein networkhttps://string-db.org/network/284812.Q09771Transcription factor atf31.
rdh54 protein networkhttps://string-db.org/network/284812.Q09772Meiotic recombination protein rdh54; Acts with rhp54 to repair meiotic double strand breaks via homologous recombination. Involved in meiotic DNA recombination. Belongs to the SNF2/RAD54 helicase [...]
mug62 protein networkhttps://string-db.org/network/284812.Q09773Meiotically up-regulated gene 62 protein; Has a role in meiosis.
atp20 protein networkhttps://string-db.org/network/284812.Q09774ATP synthase subunit g, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
rok1 protein networkhttps://string-db.org/network/284812.Q09775ATP-dependent RNA helicase rok1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading [...]
snu23 protein networkhttps://string-db.org/network/284812.Q09776U4/U6.U5 small nuclear ribonucleoprotein component snu23.
rgs1 protein networkhttps://string-db.org/network/284812.Q09777Regulator of G-protein signaling 1; Negatively regulates pheromone signaling during mating. Acts in a negative feedback loop that is essential for the mating process. This loop acts to down-regul [...]
tsc1 protein networkhttps://string-db.org/network/284812.Q09778Tuberous sclerosis 1 protein homolog; Together with tsc2, required for uptake of various amino acids from the environment and for proper conjugation. Involved in induction of gene expression of p [...]
tho2 protein networkhttps://string-db.org/network/284812.Q09779THO complex subunit 2; Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export. The THO complex is recruited to transcribed genes and [...]
erg12 protein networkhttps://string-db.org/network/284812.Q09780Putative mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Meval [...]
rps101 protein networkhttps://string-db.org/network/284812.Q0978140S ribosomal protein S1-A.
gpi7 protein networkhttps://string-db.org/network/284812.Q09782GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second manno [...]
tim8 protein networkhttps://string-db.org/network/284812.Q09783Mitochondrial import inner membrane translocase subunit tim8; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into th [...]
trs33 protein networkhttps://string-db.org/network/284812.Q09784Uncharacterized protein C13G6.05c; Belongs to the TRAPP small subunits family. BET3 subfamily.
gcv2 protein networkhttps://string-db.org/network/284812.Q09785Putative glycine dehydrogenase (decarboxylating), mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its [...]
fzr2 protein networkhttps://string-db.org/network/284812.Q09786Uncharacterized WD repeat-containing protein C13G6.08; Belongs to the WD repeat CDC20/Fizzy family.
trs402 protein networkhttps://string-db.org/network/284812.Q09787Uncharacterized protein C13G6.09; To mammalian protein PDCD2.
asl1 protein networkhttps://string-db.org/network/284812.Q09788Alkali-sensitive linkage protein 1.
SPAC13G6.13 protein networkhttps://string-db.org/network/284812.Q09789Uncharacterized protein C13G6.13.
aps1 protein networkhttps://string-db.org/network/284812.Q09790Diphosphoinositol polyphosphate phosphohydrolase aps1; Cleaves a beta-phosphate from the diphosphate groups in PP- InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinosito [...]
rcn1 protein networkhttps://string-db.org/network/284812.Q09791Uncharacterized protein C13G6.15c; Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin.
ppk8 protein networkhttps://string-db.org/network/284812.Q09792Serine/threonine-protein kinase ppk8.
nup45 protein networkhttps://string-db.org/network/284812.Q09793Nucleoporin nup45; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components [...]
ura1 protein networkhttps://string-db.org/network/284812.Q09794Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding three enzymatic activities of the pyrimidine pathway (GATase, CPSase, and ATCase). In the central sec [...]
fra1 protein networkhttps://string-db.org/network/284812.Q09795Uncharacterized peptidase C22G7.01c.
kap111 protein networkhttps://string-db.org/network/284812.Q09796Importin beta-like protein kap111; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC struc [...]
SPAC22G7.03 protein networkhttps://string-db.org/network/284812.Q09797Uncharacterized protein C22G7.03.
pan2 protein networkhttps://string-db.org/network/284812.Q09798PAN2-PAN3 deadenylation complex catalytic subunit pan2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. [...]
kri1 protein networkhttps://string-db.org/network/284812.Q09799Protein kri1; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity); Belongs to the KRI1 family.
ime4 protein networkhttps://string-db.org/network/284812.Q09800Uncharacterized protein C22G7.07c.
iss1 protein networkhttps://string-db.org/network/284812.Q09801Pre-mRNA polyadenylation factor fip1; Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase; Belongs to the FIP1 family.
cum1 protein networkhttps://string-db.org/network/284812.Q09802UPF0654 protein C22G7.11c; Belongs to the UPF0654 (con-6) family.
vps4 protein networkhttps://string-db.org/network/284812.Q09803Suppressor protein of bem1/bed5 double mutants; Involved in the transport of biosynthetic membrane proteins from the prevacuolar/endosomal compartment to the vacuole. Involved in multivesicular b [...]
urb2 protein networkhttps://string-db.org/network/284812.Q09804Probable nucleolar pre-ribosomal-associated protein 2; Required for 27S pre-rRNA processing. Has an early role during 60S ribosomal subunit assembly (By similarity).
vps45 protein networkhttps://string-db.org/network/284812.Q09805Vacuolar protein sorting-associated protein 45; Vacuolar protein sorting-associated protein involved in Golgi-to-vacuole protein transport.
rbm17 protein networkhttps://string-db.org/network/284812.Q09806Uncharacterized protein C2G11.04.
alx1 protein networkhttps://string-db.org/network/284812.Q09807pH-response regulator protein palA/rim20; Belongs to the palA/RIM20 family.
smn1 protein networkhttps://string-db.org/network/284812.Q09808Survival motor neuron-like protein 1; Has been implicated indirectly in general cellular RNA processing. Plays a crucial role in the generation of the pre-mRNA splicing machinery and in mRNA biog [...]
uba42 protein networkhttps://string-db.org/network/284812.Q09810Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the [...]
rqh1 protein networkhttps://string-db.org/network/284812.Q09811ATP-dependent DNA helicase hus2/rqh1; Has a role in the repair of UV-induced DNA damage in G2 via recombination-mediated repair. Also has a role in the repair of infrared-induced double DNA stran [...]
atg22 protein networkhttps://string-db.org/network/284812.Q09812Autophagy-related protein 22; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of prot [...]
taf1 protein networkhttps://string-db.org/network/284812.Q09813Putative transcription initiation factor TFIID 111 kDa subunit; TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase t [...]
tgs1 protein networkhttps://string-db.org/network/284812.Q09814Trimethylguanosine synthase; Catalyzes the two serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G [...]
pom2 protein networkhttps://string-db.org/network/284812.Q09815Serine/threonine-protein kinase ppk5; Has a role in meiosis; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
mta1 protein networkhttps://string-db.org/network/284812.Q09816S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of M [...]
nmd3 protein networkhttps://string-db.org/network/284812.Q0981760S ribosomal export protein nmd3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
mot2 protein networkhttps://string-db.org/network/284812.Q09818Putative general negative regulator of transcription C16C9.04c; May negatively regulate the basal and activated transcription of many genes.
cph1 protein networkhttps://string-db.org/network/284812.Q09819Uncharacterized protein C16C9.05.
upf1 protein networkhttps://string-db.org/network/284812.Q09820ATP-dependent helicase upf1; Required for rapid turnover of mRNAs containing a premature translational termination codon; Belongs to the DNA2/NAM7 helicase family.
cdc15 protein networkhttps://string-db.org/network/284812.Q09822Cell division control protein 15; After the onset of mitosis, forms a ring-like structure which colocalizes with the medial actin ring. Appears to mediate cytoskeletal rearrangements required for [...]
rec10 protein networkhttps://string-db.org/network/284812.Q09823Meiotic recombination protein rec10; Involved primarily in the early steps of meiotic recombination localized to chromosome III.
rep2 protein networkhttps://string-db.org/network/284812.Q09824Transcriptional activator protein rep2; Transcriptional activator which interacts with the mcb binding subunit complex formed by res2 and cdc10. Rep2 is required for the mitotic cell cycle start.
sad1 protein networkhttps://string-db.org/network/284812.Q09825Spindle pole body-associated protein sad1; Associates with the spindle pole body and maintains a functional interface between the nuclear membrane and the microtubule motor proteins. Involved in [...]
sds23 protein networkhttps://string-db.org/network/284812.Q09826Protein sds23/moc1; Required for normal DNA replication and for proper mitosis. Induces sexual development and ascus formation. Belongs to the SDS23 family.
sss1 protein networkhttps://string-db.org/network/284812.Q09827Probable protein transport protein Sec61 subunit gamma; Necessary for protein translocation in the endoplasmic reticulum.
SPAC4G8.09 protein networkhttps://string-db.org/network/284812.Q09828Putative leucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
puf5 protein networkhttps://string-db.org/network/284812.Q09829Pumilio domain-containing protein C4G8.03c.
SPAC4G8.04 protein networkhttps://string-db.org/network/284812.Q09830TBC domain-containing protein C4G8.04.
ppk14 protein networkhttps://string-db.org/network/284812.Q09831Serine/threonine-protein kinase ppk14; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. KIN82 subfamily.
trm12 protein networkhttps://string-db.org/network/284812.Q09832tRNA wybutosine-synthesizing protein 2; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine wit [...]
trm2 protein networkhttps://string-db.org/network/284812.Q09833tRNA (uracil(54)-C(5))-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNA. May also have a role in tRNA stabilization or maturation (By similarity); [...]
SPAC4G8.08 protein networkhttps://string-db.org/network/284812.Q09834Uncharacterized mitochondrial carrier C4G8.08.
gos1 protein networkhttps://string-db.org/network/284812.Q09835Protein transport protein gos1; Nonessential SNARE involved in retrograde transport within the Golgi complex.
atp10 protein networkhttps://string-db.org/network/284812.Q09836Probable mitochondrial ATPase complex subunit atp10; Involved in assembly of the mitochondrial F1-F0 complex. Belongs to the ATP10 family.
smp3 protein networkhttps://string-db.org/network/284812.Q09837GPI mannosyltransferase 4; Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly [...]
prz1 protein networkhttps://string-db.org/network/284812.Q09838Transcriptional regulator prz1; Involved in the regulation of calcium ion homeostasis. Binds to the calcineurin-dependent response element. Transcriptionally regulates pmc1.
SPAC16C9.01c protein networkhttps://string-db.org/network/284812.Q09839Uncharacterized protein C16C9.01c.
aah2 protein networkhttps://string-db.org/network/284812.Q09840Alpha-amylase 2.
pup1 protein networkhttps://string-db.org/network/284812.Q09841Probable proteasome subunit beta type-2; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent t [...]
pdp3 protein networkhttps://string-db.org/network/284812.Q09842PWWP domain-containing protein 3; Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3 [...]
rfc2 protein networkhttps://string-db.org/network/284812.Q09843Replication factor C subunit 2; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. Subunit 2 binds ATP [...]
SPAC23D3.03c protein networkhttps://string-db.org/network/284812.Q09844TBC domain-containing protein C23D3.03c.
gpd2 protein networkhttps://string-db.org/network/284812.Q09845Glycerol-3-phosphate dehydrogenase [NAD(+)] 2; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
nup146 protein networkhttps://string-db.org/network/284812.Q09847Nucleoporin nup146; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural component [...]
usp108 protein networkhttps://string-db.org/network/284812.Q09848U1 snRNP-associated protein usp108; Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the splice [...]
arp42 protein networkhttps://string-db.org/network/284812.Q09849SWI/SNF and RSC complexes subunit arp42; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particul [...]
eng2 protein networkhttps://string-db.org/network/284812.Q09850Putative endo-1,3(4)-beta-glucanase 2; Belongs to the glycosyl hydrolase 81 family.
ayr1 protein networkhttps://string-db.org/network/284812.Q09851NADPH-dependent 1-acyldihydroxyacetone phosphate reductase; Can convert acyl and alkyl dihydroxyacetone-phosphate (DHAP) into glycerolipids and ether lipids, respectively. Required for the biosyn [...]
pho842 protein networkhttps://string-db.org/network/284812.Q09852Putative inorganic phosphate transporter C23D3.12; High-affinity transporter for external inorganic phosphate. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
SPAC23D3.13c protein networkhttps://string-db.org/network/284812.Q09853Protein MON2 homolog; Required for traffic between late Golgi and early endosomes. Required for endocytosis and maintenance of vacuolar structure (By similarity).
mok11 protein networkhttps://string-db.org/network/284812.Q09854Cell wall alpha-1,3-glucan synthase mok11.
pof11 protein networkhttps://string-db.org/network/284812.Q09855F-box/WD repeat-containing protein pof11; Has a role in meiosis.
prp3 protein networkhttps://string-db.org/network/284812.Q09856U4/U5/U6 small nuclear ribonucleoprotein prp3; Participates in pre-mRNA splicing and in nuclear mRNA export. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex.
uso1 protein networkhttps://string-db.org/network/284812.Q09857Intracellular protein transport protein uso1; Required for protein transport from the ER to the Golgi complex; Belongs to the VDP/USO1/EDE1 family.
nnf1 protein networkhttps://string-db.org/network/284812.Q09858Kinetochore protein nnf1; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycl [...]
mxr1 protein networkhttps://string-db.org/network/284812.Q09859Probable peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of [...]
SPAC29E6.06c protein networkhttps://string-db.org/network/284812.Q09860Probable cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
SPAC29E6.09 protein networkhttps://string-db.org/network/284812.Q09862Uncharacterized protein C29E6.09.
nst1 protein networkhttps://string-db.org/network/284812.Q09863Stress response protein nst1; May act as a negative regulator of salt tolerance. Belongs to the NST1 family.
mcp60 protein networkhttps://string-db.org/network/284812.Q09864Heat shock protein 60, mitochondrial; May participate in assembly and/or disassembly of proteins imported into the mitochondrion. HSP60 are ATPases and have affinity for unfolded proteins; Belong [...]
mrpl6 protein networkhttps://string-db.org/network/284812.Q09865Putative 54S ribosomal protein L6, mitochondrial.
sea4 protein networkhttps://string-db.org/network/284812.Q09866Uncharacterized WD repeat-containing protein C12G12.01c; Belongs to the WD repeat mio family.
efg1 protein networkhttps://string-db.org/network/284812.Q09867rRNA-processing protein efg1; Involved in rRNA processing; Belongs to the EFG1 family.
cip2 protein networkhttps://string-db.org/network/284812.Q09868RNA-binding post-transcriptional regulator cip2; Regulates global gene expression after oxidative stress. Interacts and stabilizes mRNAs and may regulate their transition between different cytopl [...]
taf9 protein networkhttps://string-db.org/network/284812.Q09869Transcription initiation factor TFIID subunit 9; TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcription.
rcl1 protein networkhttps://string-db.org/network/284812.Q09870Probable RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 a [...]
SPAC12G12.07c protein networkhttps://string-db.org/network/284812.Q09871Uncharacterized protein C12G12.07c.
eti1 protein networkhttps://string-db.org/network/284812.Q09872Uncharacterized protein C12G12.09.
wdr21 protein networkhttps://string-db.org/network/284812.Q09873WD repeat-containing protein 21.
miy1 protein networkhttps://string-db.org/network/284812.Q09874Uncharacterized protein C12G12.11c; To yeast YGL082w.
gms2 protein networkhttps://string-db.org/network/284812.Q09875Uncharacterized protein C12G12.12.
sif3 protein networkhttps://string-db.org/network/284812.Q09877Sad1-interacting factor 3; Belongs to the RMD1/sif2 family.
met10 protein networkhttps://string-db.org/network/284812.Q09878Probable sulfite reductase [NADPH] flavoprotein component; This enzyme catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of [...]
ubp5 protein networkhttps://string-db.org/network/284812.Q09879Probable ubiquitin carboxyl-terminal hydrolase 5.
prp45 protein networkhttps://string-db.org/network/284812.Q09882Pre-mRNA-processing protein 45; Involved in pre-mRNA splicing; Belongs to the SNW family.
spn6 protein networkhttps://string-db.org/network/284812.Q09883Septin homolog spn6; Septin-like protein involved in the correct orientation of forespore membrane extension during sporulation.
dcr1 protein networkhttps://string-db.org/network/284812.Q09884ATP-dependent helicase dcr1; Required for G1 arrest and mating in response to nitrogen starvation. Ago1 regulation of cytokinesis and cell cycle checkpoints occurs downstream of dcr1. Required, i [...]
svf1 protein networkhttps://string-db.org/network/284812.Q09885Survival factor 1; May be involved in the response to oxidative stress. Belongs to the SVF1 family.
SPCC584.13 protein networkhttps://string-db.org/network/284812.Q09887Uncharacterized amino-acid permease C584.13.
mug160 protein networkhttps://string-db.org/network/284812.Q09888Meiotically up-regulated gene 160 protein.
aly3 protein networkhttps://string-db.org/network/284812.Q09889Arrestin domain-containing protein C584.15c; Belongs to the arrestin family.
dnf2 protein networkhttps://string-db.org/network/284812.Q09891Putative phospholipid-transporting ATPase C24B11.12c; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
sty1 protein networkhttps://string-db.org/network/284812.Q09892Mitogen-activated protein kinase sty1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. [...]
SPAC24B11.05 protein networkhttps://string-db.org/network/284812.Q09893Uncharacterized protein C24B11.05; Belongs to the SSM1 family.
erv46 protein networkhttps://string-db.org/network/284812.Q09895Uncharacterized protein C24B11.08c.
mpc2 protein networkhttps://string-db.org/network/284812.Q09896Probable mitochondrial pyruvate carrier 2; Mediates the uptake of pyruvate into mitochondria.
cfh1 protein networkhttps://string-db.org/network/284812.Q09897Chitin synthase regulatory factor 3.
sid2 protein networkhttps://string-db.org/network/284812.Q09898Serine/threonine-protein kinase sid2; Part of a signaling pathway. Required for initiation of medial ring constriction and septation; Belongs to the protein kinase superfamily. Ser/Thr protein ki [...]
hem3 protein networkhttps://string-db.org/network/284812.Q09899Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
rpl3802 protein networkhttps://string-db.org/network/284812.Q0990060S ribosomal protein L38-2.
gto2 protein networkhttps://string-db.org/network/284812.Q09901Uncharacterized family 31 glucosidase C30D11.01c; Belongs to the glycosyl hydrolase 31 family.
ddx27 protein networkhttps://string-db.org/network/284812.Q09903ATP-dependent RNA helicase drs1; ATP-binding RNA helicase involved in ribosome assembly.
nup124 protein networkhttps://string-db.org/network/284812.Q09904Nucleoporin nup124; Nucleoporins may be involved in both binding and translocation of the proteins during nucleocytoplasmic transport. In S.pombe it is required for the nuclear localization of re [...]
aps3 protein networkhttps://string-db.org/network/284812.Q09905AP-3 complex subunit sigma; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral struc [...]
hfl1 protein networkhttps://string-db.org/network/284812.Q09906Transmembrane protein 184 homolog C30D11.06c.
nth1 protein networkhttps://string-db.org/network/284812.Q09907Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair [...]
phf2 protein networkhttps://string-db.org/network/284812.Q09908SWM histone demethylase complex subunit phf2; Component of the SWM histone demethylase complex that specifically demethylates H3K9me2, a specific tag for epigenetic transcriptional activation, th [...]
cwf19 protein networkhttps://string-db.org/network/284812.Q09909Pre-mRNA-splicing factor cwf19; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome; Belongs to the CWF19 family.
izh3 protein networkhttps://string-db.org/network/284812.Q09910Uncharacterized protein C30D11.11.
SPAC30D11.14c protein networkhttps://string-db.org/network/284812.Q09911Uncharacterized protein C30D11.14c.
psi1 protein networkhttps://string-db.org/network/284812.Q09912Protein psi1; Required for nuclear migration during mitosis. It is required for the normal initiation of translation.
dal2 protein networkhttps://string-db.org/network/284812.Q09913Probable allantoicase; Utilization of purines as secondary nitrogen sources, when primary sources are limiting.
rho1 protein networkhttps://string-db.org/network/284812.Q09914GTP-binding protein rho1; Involved in the regulation of cell wall growth and actin cytoskeleton organization. Activates (1,3)-beta-D-glucan synthase. Belongs to the small GTPase superfamily. Rho [...]
spt6 protein networkhttps://string-db.org/network/284812.Q09915Transcription elongation factor spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic [...]
has1 protein networkhttps://string-db.org/network/284812.Q09916ATP-dependent RNA helicase has1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading [...]
pkd2 protein networkhttps://string-db.org/network/284812.Q09917TRP-like ion channel pkd2; Acts as a key signaling component in the regulation of cell shape and cell wall synthesis through interaction with GTPase Rho1.
hsp3105 protein networkhttps://string-db.org/network/284812.Q09918Putative glutathione-independent glyoxalase hsp3105; May catalyze the conversion of methylglyoxal (MG) to D- lactate in a single glutathione (GSH)-independent step. May play a role in detoxifying [...]
fip1 protein networkhttps://string-db.org/network/284812.Q09919Plasma membrane iron permease; Permease for high affinity iron uptake. Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
fio1 protein networkhttps://string-db.org/network/284812.Q09920Iron transport multicopper oxidase fio1; Could be an iron transport multicopper oxidase, which is required for Fe(2+) high affinity uptake. May be required to oxidize Fe(2+) and release it from t [...]
SPAC1F7.10 protein networkhttps://string-db.org/network/284812.Q09921Uncharacterized protein C1F7.10; Belongs to the HyuE racemase family.
SPAC1F7.11c protein networkhttps://string-db.org/network/284812.Q09922Uncharacterized transcriptional regulatory protein C1F7.11c.
yak3 protein networkhttps://string-db.org/network/284812.Q09923Aldo-keto reductase yakc [NADP(+)].
tif224 protein networkhttps://string-db.org/network/284812.Q09924Probable translation initiation factor eIF-2B subunit delta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family.
lcb2 protein networkhttps://string-db.org/network/284812.Q09925Serine palmitoyltransferase 2; Catalytic subunit of serine palmitoyltransferase (SPT), which catalyzes the committed step in the synthesis of sphingolipids, the condensation of serine with palmit [...]
pcr1 protein networkhttps://string-db.org/network/284812.Q09926Transcription factor pcr1; Involved in regulation of gene expression for sexual development. Binds and activates meiotic recombination hot spot ade6- M26.
aca1 protein networkhttps://string-db.org/network/284812.Q09927N-acetyltransferase aca1; N-acetyltransferase involved in oxidative stress resistance. Acetylates the toxic proline metabolism intermediate (S)-1-pyrroline-5- carboxylate (P5C), or more likely it [...]
cyp8 protein networkhttps://string-db.org/network/284812.Q09928Peptidyl-prolyl cis-trans isomerase cyp8; May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as [...]
iba57 protein networkhttps://string-db.org/network/284812.Q09929Putative transferase caf17, mitochondrial.
dis1 protein networkhttps://string-db.org/network/284812.Q09933Phosphoprotein p93; Has a role in sister chromatid separation.
rsc4 protein networkhttps://string-db.org/network/284812.Q09948Chromatin structure-remodeling complex subunit rsc4; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Contr [...]
stn1 protein networkhttps://string-db.org/network/284812.Q0E7J7Protein stn1; Required for telomere maintenance.
rev7 protein networkhttps://string-db.org/network/284812.Q0E7J8DNA polymerase zeta processivity subunit; Required for DNA damage induced mutagenesis. Involved in DNA repair, mitochondrial DNA repair and translesion synthesis. Has a role in the bypass of abas [...]
fal1 protein networkhttps://string-db.org/network/284812.Q10055ATP-dependent RNA helicase fal1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading [...]
shk2 protein networkhttps://string-db.org/network/284812.Q10056Serine/threonine-protein kinase shk2; Forms an activated complex with GTP-bound Ras-like cdc42. Participates in Ras-dependent morphological control and mating response pathways.
pdi1 protein networkhttps://string-db.org/network/284812.Q10057Putative protein disulfide-isomerase C1F5.02; Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.
SPAC1F5.03c protein networkhttps://string-db.org/network/284812.Q10058Putative oxidoreductase C1F5.03c; Putative oxidoreductase that negatively regulates the retrieval of cargo from late endosomes to the Golgi; Belongs to the TDA3 family.
cdc12 protein networkhttps://string-db.org/network/284812.Q10059Cell division control protein 12; Plays a role in the cell cycle. Involved in cytokinesis. Component of the cell division ring. In the absence of profilin, caps the barbed end of actin filaments, [...]
mso1 protein networkhttps://string-db.org/network/284812.Q10060Uncharacterized protein C1F5.05c.
lsh1 protein networkhttps://string-db.org/network/284812.Q10061Heat shock protein 70 homolog lhs1; Chaperone required for protein translocation and folding in the endoplasmic reticulum.
hem14 protein networkhttps://string-db.org/network/284812.Q10062Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
yam8 protein networkhttps://string-db.org/network/284812.Q10063Calcium influx-promoting protein ehs1; Required for Ca(2+) influx and for vitality of cells in a late, pheromone-induced event of the mating process requiring calcium- induced signaling; To yeast [...]
tra2 protein networkhttps://string-db.org/network/284812.Q10064Uncharacterized PI3/PI4-kinase family protein C1F5.11c; Belongs to the PI3/PI4-kinase family.
trk2 protein networkhttps://string-db.org/network/284812.Q10065Potassium transport protein 2; Together with TRK1, defines the major, high-affinity potassium influx transport system. Involved in maintenance of the proper sodium/potassium ratio in the cell and [...]
aru1 protein networkhttps://string-db.org/network/284812.Q10066Arginase; Belongs to the arginase family.
orc3 protein networkhttps://string-db.org/network/284812.Q10067Origin recognition complex subunit 3; Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcript [...]
sdd3 protein networkhttps://string-db.org/network/284812.Q10068Uncharacterized protein C3H1.02c.
mug151 protein networkhttps://string-db.org/network/284812.Q10069Meiotically up-regulated gene 151 protein; Has a role in meiosis.
mdm31 protein networkhttps://string-db.org/network/284812.Q10070Mitochondrial distribution and morphology protein 31; Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial dis [...]
ste24 protein networkhttps://string-db.org/network/284812.Q10071Probable CAAX prenyl protease 1; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
SPAC3H1.08c protein networkhttps://string-db.org/network/284812.Q10073Uncharacterized CCDC90 family protein C3H1.08c, mitochondrial.
avt3 protein networkhttps://string-db.org/network/284812.Q10074Vacuolar amino acid transporter 3; Involved in amino acid efflux from the vacuole to the cytoplasm. Capable of transporting large neutral amino acids including tyrosine, glutamine, asparagine, is [...]
pcs2 protein networkhttps://string-db.org/network/284812.Q10075Glutathione gamma-glutamylcysteinyltransferase; Required for detoxification of heavy metals such as cadmium and arsenate.
hsr1 protein networkhttps://string-db.org/network/284812.Q10076Hydrogen peroxide stress regulator 1; Transcription factor that globally supports gene expression in response to hydrogen peroxide.
snt2 protein networkhttps://string-db.org/network/284812.Q10077Lid2 complex component snt2.
ppk13 protein networkhttps://string-db.org/network/284812.Q10078Serine/threonine-protein kinase ppk13.
gid4 protein networkhttps://string-db.org/network/284812.Q10079Uncharacterized protein C3H1.14.
SPAC11D3.01c protein networkhttps://string-db.org/network/284812.Q10080UPF0654 protein C11D3.01c; Belongs to the UPF0654 (con-6) family.
SPAC11D3.02c protein networkhttps://string-db.org/network/284812.Q10081UPF0039 protein C11D3.02c; Belongs to the UPF0039 (ElaA) family.
SPAC11D3.03c protein networkhttps://string-db.org/network/284812.Q10082Uncharacterized protein C11D3.03c.
SPAC11D3.04c protein networkhttps://string-db.org/network/284812.Q10083Uncharacterized protein C11D3.04c.
mfs2 protein networkhttps://string-db.org/network/284812.Q10084Uncharacterized transporter mfs2.
SPAC11D3.06 protein networkhttps://string-db.org/network/284812.Q10085Uncharacterized transporter C11D3.06.
SPAC11D3.08c protein networkhttps://string-db.org/network/284812.Q10087Uncharacterized amino-acid permease C11D3.08c.
SPAC11D3.09 protein networkhttps://string-db.org/network/284812.Q10088Putative agmatinase 1; Belongs to the arginase family.
SPAC11D3.10 protein networkhttps://string-db.org/network/284812.Q10089Uncharacterized protein C11D3.10.
hsp3104 protein networkhttps://string-db.org/network/284812.Q10092Probable glutathione-independent glyoxalase hsp3104; Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step. May play a role in detoxifying end [...]
SPAC11D3.14c protein networkhttps://string-db.org/network/284812.Q10093Uncharacterized protein C11D3.14c; Belongs to the oxoprolinase family.
SPAC11D3.15 protein networkhttps://string-db.org/network/284812.Q10094Uncharacterized protein C11D3.15; Belongs to the oxoprolinase family.
SPAC11D3.17 protein networkhttps://string-db.org/network/284812.Q10096Zinc finger protein C11D3.17.
SPAC11D3.18c protein networkhttps://string-db.org/network/284812.Q10097Uncharacterized transporter C11D3.18C.
glm1 protein networkhttps://string-db.org/network/284812.Q10098Uncharacterized protein C15F9.01c.
seh1 protein networkhttps://string-db.org/network/284812.Q10099Nucleoporin seh1; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components [...]
nxt2 protein networkhttps://string-db.org/network/284812.Q10100Nuclear transport factor 2; Facilitates protein transport into the nucleus. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import ( [...]
rps7 protein networkhttps://string-db.org/network/284812.Q1010140S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.
SPAC18G6.01c protein networkhttps://string-db.org/network/284812.Q10102Uncharacterized protein C18G6.01c.
chp1 protein networkhttps://string-db.org/network/284812.Q10103Chromo domain-containing protein 1; Component of the kinetochore which plays a role in stabilizing microtubules and so allowing accurate chromosome segregation. Has a role in the RNA interference [...]
shm2 protein networkhttps://string-db.org/network/284812.Q10104Serine hydroxymethyltransferase, mitochondrial; Interconversion of serine and glycine; Belongs to the SHMT family.
gcn1 protein networkhttps://string-db.org/network/284812.Q10105eIF-2-alpha kinase activator gcn1; Acts as a positive activator of the gcn2 protein kinase activity in response to amino acid starvation. Component of the gcn1- gcn20 complex that forms a complex [...]
utp11 protein networkhttps://string-db.org/network/284812.Q10106Probable U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.
mra1 protein networkhttps://string-db.org/network/284812.Q10107Ribosomal RNA small subunit methyltransferase mra1; S-adenosyl-L-methionine-dependent pseudouridine N(1)- methyltransferase that methylates the pseudouridine corresponding to position 1189 (Psi11 [...]
edc1 protein networkhttps://string-db.org/network/284812.Q10108Uncharacterized protein C18G6.09c.
lem2 protein networkhttps://string-db.org/network/284812.Q10109Lap-Emerin-Man domain protein 2; Nucleus inner membrane protein involved in meiosis.
rrn3 protein networkhttps://string-db.org/network/284812.Q10110RNA polymerase I-specific transcription initiation factor rrn3; Required for efficient transcription initiation by RNA polymerase I; Belongs to the RRN3 family.
SPAC18G6.12c protein networkhttps://string-db.org/network/284812.Q10111Uncharacterized protein C18G6.12c; To S.pombe SpAC14C4.04.
SPAC18G6.13 protein networkhttps://string-db.org/network/284812.Q10112Uncharacterized protein C18G6.13.
mal3 protein networkhttps://string-db.org/network/284812.Q10113Microtubule integrity protein mal3; May play a role in regulating the integrity of microtubules possibly by influencing their stability. Involved in an anchoring mechanism to maintain tea2 and ti [...]
idi1 protein networkhttps://string-db.org/network/284812.Q10132Isopentenyl-diphosphate Delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphospha [...]
rho2 protein networkhttps://string-db.org/network/284812.Q10133GTP-binding protein rho2; Involved in cell morphogenesis, the maintenance of growth direction, control of polarity and of cell wall integrity. Regulates the synthesis of alpha-D-glucan through ac [...]
fep1 protein networkhttps://string-db.org/network/284812.Q10134Iron-sensing transcription factor 1; Represses the expression of the iron transporter fio1 in response to high iron concentrations. Binds to the consensus sequence 5'-[AT]GATAA-3'. Also represses [...]
lsd2 protein networkhttps://string-db.org/network/284812.Q10135Lysine-specific histone demethylase 2; Catalytic component of the SWM histone demethylase complex that specifically demethylates H3K9me2, a specific tag for epigenetic transcriptional activation, [...]
ste7 protein networkhttps://string-db.org/network/284812.Q10136Protein ste7; Has a role in promoting meiosis whereby it is involved in establishing the mating pheromone signaling pathway. It also has a role in suppressing meiosis until the conjugation proces [...]
spo20 protein networkhttps://string-db.org/network/284812.Q10137Sec14 cytosolic factor; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Ess [...]
csr102 protein networkhttps://string-db.org/network/284812.Q10138CRAL-TRIO domain-containing protein C3H8.02.
img2 protein networkhttps://string-db.org/network/284812.Q1013954S ribosomal protein img2, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL49 family.
SPAC3H8.04 protein networkhttps://string-db.org/network/284812.Q10140Uncharacterized protein C3H8.04.
mms1 protein networkhttps://string-db.org/network/284812.Q10141Uncharacterized protein C3H8.05c.
aur1 protein networkhttps://string-db.org/network/284812.Q10142Inositol phosphorylceramide synthase catalytic subunit aur1; Catalytic component of the inositol phosphorylceramide synthase which catalyzes the addition of a phosphorylinositol group onto cerami [...]
pfd3 protein networkhttps://string-db.org/network/284812.Q10143Probable prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in [...]
nab3 protein networkhttps://string-db.org/network/284812.Q10145Uncharacterized RNA-binding protein C3H8.09c.
rrp6 protein networkhttps://string-db.org/network/284812.Q10146Exosome complex exonuclease rrp6; Nuclear-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA process [...]
cct2 protein networkhttps://string-db.org/network/284812.Q10147Probable T-complex protein 1 subunit beta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By simila [...]
tls1 protein networkhttps://string-db.org/network/284812.Q10148Telomere length and silencing protein 1; Involved in the regulation of heterochromatin assembly at telomeric regions. Involved in the control of telomere length. Regulates spliceosome assembly by [...]
grh1 protein networkhttps://string-db.org/network/284812.Q10149Uncharacterized protein C1D4.02c.
aut12 protein networkhttps://string-db.org/network/284812.Q10150Vacuolar fusion protein mon1; Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis; Belongs to the MON1/SAND fa [...]
erd101 protein networkhttps://string-db.org/network/284812.Q10151Protein ERD1 homolog 2.
pis1 protein networkhttps://string-db.org/network/284812.Q10153CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
rtf2 protein networkhttps://string-db.org/network/284812.Q10154Replication termination factor 2; Replication termination factor which mediates replication termination at the site-specific replication barrier RTS1. Stabilizes the replication fork stalled at R [...]
trz1 protein networkhttps://string-db.org/network/284812.Q10155Ribonuclease Z 1; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. May be involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Belongs [...]
lkh1 protein networkhttps://string-db.org/network/284812.Q10156Dual specificity protein kinase lkh1; Protein kinase that may act as a negative regulator of filamentous growth and flocculation. Appears to have a role in normal cell wall and septum formation a [...]
myh1 protein networkhttps://string-db.org/network/284812.Q10159Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. Has glycosylase and nicking activities and is active at A/G and A/GO sites.
rmi1 protein networkhttps://string-db.org/network/284812.Q10160RecQ-mediated genome instability protein 1; Structure-specific DNA-binding protein with a preference for cruciform structures. Also binds single-stranded DNA (ssDNA). Functions together with top3 [...]
chc1 protein networkhttps://string-db.org/network/284812.Q10161Probable clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
bud23 protein networkhttps://string-db.org/network/284812.Q1016218S rRNA (guanine-N(7))-methyltransferase bud23; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA. Important for biogene [...]
smb1 protein networkhttps://string-db.org/network/284812.Q10163Small nuclear ribonucleoprotein-associated protein B; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site (By [...]
rga2 protein networkhttps://string-db.org/network/284812.Q10164Probable Rho-type GTPase-activating protein 2; GTPase-activating protein for Rho-type proteins.
cnt6 protein networkhttps://string-db.org/network/284812.Q10165Probable ribosylation factor GTPase-activating protein cnt6; GTPase-activating protein for the ADP ribosylation factor family.
SPAC26A3.11 protein networkhttps://string-db.org/network/284812.Q10166Hydrolase C26A3.11; Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
nsp1 protein networkhttps://string-db.org/network/284812.Q10168Nucleoporin nsp1; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components [...]
dsk2 protein networkhttps://string-db.org/network/284812.Q10169Deubiquitination-protection protein dph1; Protects ubiquitin chains against dissambly by deubiquitinating enzymes thereby promoting protein degradation.
rmt2 protein networkhttps://string-db.org/network/284812.Q10170Protein arginine N-methyltransferase 2; S-adenosyl-L-methionine-dependent protein-arginine N- methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylargin [...]
uch1 protein networkhttps://string-db.org/network/284812.Q10171Probable ubiquitin carboxyl-terminal hydrolase 1; Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol prot [...]
pan1 protein networkhttps://string-db.org/network/284812.Q10172Actin cytoskeleton-regulatory complex protein pan1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The [...]
nuf2 protein networkhttps://string-db.org/network/284812.Q10173Kinetochore protein nuf2; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycl [...]
SPAC27F1.05c protein networkhttps://string-db.org/network/284812.Q10174Uncharacterized aminotransferase C27F1.05c.
ani2 protein networkhttps://string-db.org/network/284812.Q10175Probable peptidyl-prolyl cis-trans isomerase C27F1.06c; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By s [...]
ost1 protein networkhttps://string-db.org/network/284812.Q10176Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Ma [...]
pdt1 protein networkhttps://string-db.org/network/284812.Q10177Manganese transporter pdt1; Transports manganese ions into the cell. Regulates cell morphogenesis through control of manganese homeostasis. Belongs to the NRAMP family.
prp10 protein networkhttps://string-db.org/network/284812.Q10178U2 snRNP component prp10; Contacts pre-mRNA on both sides of the branch site early in spliceosome assembly; Belongs to the SF3B1 family.
grs1 protein networkhttps://string-db.org/network/284812.Q10179Putative glycine--tRNA ligase; Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces [...]
mug113 protein networkhttps://string-db.org/network/284812.Q10180Meiotically up-regulated gene 113 protein; Has a role in meiosis.
rit1 protein networkhttps://string-db.org/network/284812.Q10181Uncharacterized protein C3F10.06c; To yeast RIT1.
erf4 protein networkhttps://string-db.org/network/284812.Q10182Ras modification protein erf4; The erf2-erf4 complex is a palmitoyltransferase specific for Ras proteins. Palmitoylates RAS2, which is required for its proper plasma membrane localization (By sim [...]
faf1 protein networkhttps://string-db.org/network/284812.Q10183Uncharacterized protein C3F10.08c.
his6 protein networkhttps://string-db.org/network/284812.Q101841-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
abc2 protein networkhttps://string-db.org/network/284812.Q10185ATP-binding cassette transporter abc2; Involved in vacuolar sequestration of glutathione S- conjugates. Together with abc4, required for accumulation of a red pigment (ade pigment) in the vacuole [...]
SPAC3F10.12c protein networkhttps://string-db.org/network/284812.Q10186Uncharacterized bHLH domain-containing protein C3F10.12c.
ucp6 protein networkhttps://string-db.org/network/284812.Q10187UBA domain-containing protein 6.
spo12 protein networkhttps://string-db.org/network/284812.Q10189Mitosis-specific protein spo12; Has a role in controlling mitotic cell cycle progression at the G2/M transition phase.
SPAC3F10.16c protein networkhttps://string-db.org/network/284812.Q10190Large subunit GTPase 1; GTPase required for the nuclear export of the 60S ribosomal subunit. Acts by mediating the release of nmd3 from the 60S ribosomal subunit after export into the cytoplasm ( [...]
ltv1 protein networkhttps://string-db.org/network/284812.Q10191Protein LTV1; Involved in protein transport. Non-ribosomal factor required for efficient nuclear export of the ribosomal 40S subunit. May participate in intracellular sorting of GAP1 out of the e [...]
rpl1801 protein networkhttps://string-db.org/network/284812.Q1019260S ribosomal protein L18-A.
srp1 protein networkhttps://string-db.org/network/284812.Q10193Pre-mRNA-splicing factor srp1; Has a role in pre-mRNA splicing where it is involved in spliceosome assembly.
SPBC11C11.06c protein networkhttps://string-db.org/network/284812.Q10195Uncharacterized protein C11C11.06c.
knh1 protein networkhttps://string-db.org/network/284812.Q10196Uncharacterized protein C11C11.05.
alp1 protein networkhttps://string-db.org/network/284812.Q10197Tubulin-folding cofactor D; Has a function in the folding of beta-tubulin. Microtubule- associated protein that is essential to direct polarized cell growth and to position the nucleus and septum [...]
ndc80 protein networkhttps://string-db.org/network/284812.Q10198Kinetochore protein ndc80; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cyc [...]
imp2 protein networkhttps://string-db.org/network/284812.Q10199Septation protein imp2; Required for normal septation. Involved in the disassembly of the medial ring during septation.
SPBC11C11.01 protein networkhttps://string-db.org/network/284812.Q10200Uncharacterized protein C11C11.01.
npg1 protein networkhttps://string-db.org/network/284812.Q10201Uncharacterized protein C17D1.07c.
dbp3 protein networkhttps://string-db.org/network/284812.Q10202ATP-dependent RNA helicase dbp3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary f [...]
SPBC17D1.05 protein networkhttps://string-db.org/network/284812.Q10203Uncharacterized protein C17D1.05.
acr1 protein networkhttps://string-db.org/network/284812.Q10204RNA polymerase I-specific transcription initiation factor RRN9 homolog; Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I [...]
rrp43 protein networkhttps://string-db.org/network/284812.Q10205Exosome complex component rrp43; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrad [...]
dph2 protein networkhttps://string-db.org/network/284812.Q102062-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidi [...]
pyk1 protein networkhttps://string-db.org/network/284812.Q10208Pyruvate kinase.
SPAC4H3.01 protein networkhttps://string-db.org/network/284812.Q10209Uncharacterized J domain-containing protein C4H3.01.
swc3 protein networkhttps://string-db.org/network/284812.Q10210SWR1 complex subunit swc3; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected gene [...]
SPAC4H3.03c protein networkhttps://string-db.org/network/284812.Q10211Uncharacterized protein C4H3.03c.
SPAC4H3.04c protein networkhttps://string-db.org/network/284812.Q10212MEMO1 family protein C4H3.04c; Belongs to the MEMO1 family.
srs2 protein networkhttps://string-db.org/network/284812.Q10213ATP-dependent DNA helicase srs2; ATP-dependent DNA helicase involved in DNA repair at least for UV-induced lesions. Also aids the recombinational repair of camptothecin-induced collapsed replicat [...]
SPAC4H3.06 protein networkhttps://string-db.org/network/284812.Q10214Uncharacterized protein C4H3.06.
rdl2 protein networkhttps://string-db.org/network/284812.Q10215Putative thiosulfate sulfurtransferase, mitochondrial; Thiosulfate sulfurtransferase which catalyzes the transfer of sulfane sulfur from thiosulfate to cyanide.
SPAC4H3.08 protein networkhttps://string-db.org/network/284812.Q10216Uncharacterized oxidoreductase C4H3.08; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
SPAC4H3.09 protein networkhttps://string-db.org/network/284812.Q10217Putative acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). May be involved in the synthesis of very- long-chain fatty acids; [...]
ppc89 protein networkhttps://string-db.org/network/284812.Q10218Spindle pole body protein ppc89; Has a role in meiosis.
pcc1 protein networkhttps://string-db.org/network/284812.Q10220EKC/KEOPS complex subunit SPAC4H3.13; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read c [...]
rng8 protein networkhttps://string-db.org/network/284812.Q10221Uncharacterized protein C4H3.14c.
pta1 protein networkhttps://string-db.org/network/284812.Q10222mRNA cleavage and polyadenylation specificity factor complex subunit pta1; Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent [...]
pof14 protein networkhttps://string-db.org/network/284812.Q10223F-box protein pof14; Expression is induced during oxidative stress. Plays an essential, SCF-independent, role in the stress response to hydrogen peroxide for survival, by negatively regulating er [...]
trm9 protein networkhttps://string-db.org/network/284812.Q10224tRNA (carboxymethyluridine(34)-5-O)-methyltransferase; Required for the methylation of the wobble bases at position 34 in tRNA. Appears to have a role in stress-response (By similarity).
btb3 protein networkhttps://string-db.org/network/284812.Q10225BTB/POZ domain-containing protein 3; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of tar [...]
SPAC2E12.03c protein networkhttps://string-db.org/network/284812.Q10227Uncharacterized protein C2E12.03c.
erg7 protein networkhttps://string-db.org/network/284812.Q10231Lanosterol synthase; Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus.
rpl901 protein networkhttps://string-db.org/network/284812.Q1023260S ribosomal protein L9-A.
rpc2 protein networkhttps://string-db.org/network/284812.Q10233DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest co [...]
mrp5 protein networkhttps://string-db.org/network/284812.Q10234Probable 37S ribosomal protein S5, mitochondrial.
alp11 protein networkhttps://string-db.org/network/284812.Q10235Cell polarity protein alp11; Required for microtubule function and cell polarity. Involved in the proper folding of alpha-tubulin.
rnh201 protein networkhttps://string-db.org/network/284812.Q10236Ribonuclease H2 subunit A; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication.
pcf11 protein networkhttps://string-db.org/network/284812.Q10237Uncharacterized protein C4G9.04c.
mpf1 protein networkhttps://string-db.org/network/284812.Q10238Meiotic PUF family protein 1; RNA-binding protein essential for meiotic progression.
chz1 protein networkhttps://string-db.org/network/284812.Q10239Histone H2A.Z-specific chaperone chz1; Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin.
mug133 protein networkhttps://string-db.org/network/284812.Q10240Meiotically up-regulated gene 133 protein; Has a role in meiosis; Belongs to the UPF0300 family.
cmb1 protein networkhttps://string-db.org/network/284812.Q10241Mismatch-binding protein cmb1; Binds to cytosines in base mismatches and opposite chemically altered guanines.
idn1 protein networkhttps://string-db.org/network/284812.Q10242Probable gluconokinase; Belongs to the gluconokinase GntK/GntV family.
vps26 protein networkhttps://string-db.org/network/284812.Q10243Vacuolar protein sorting-associated protein 26; Plays a role in vesicular protein sorting. Required for the endosome-to-Golgi retrieval of the vacuolar protein sorting receptor pep1/vps10. Compon [...]
sym1 protein networkhttps://string-db.org/network/284812.Q10244Uncharacterized protein C4G9.14.
ifa38 protein networkhttps://string-db.org/network/284812.Q10245Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. [...]
SPAC4G9.19 protein networkhttps://string-db.org/network/284812.Q10247Uncharacterized J domain-containing protein C4G9.19.
ymc1 protein networkhttps://string-db.org/network/284812.Q10248Uncharacterized mitochondrial carrier C4G9.20c.
cmr2 protein networkhttps://string-db.org/network/284812.Q10250Uncharacterized protein C56F8.02.
tif52 protein networkhttps://string-db.org/network/284812.Q10251Eukaryotic translation initiation factor 5B; Plays a role in translation initiation. Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex [...]
ppt1 protein networkhttps://string-db.org/network/284812.Q102524-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction [...]
mug64 protein networkhttps://string-db.org/network/284812.Q10253Meiotically up-regulated gene 64 protein; Has a role in meiosis.
alg10 protein networkhttps://string-db.org/network/284812.Q10254Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase; Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose fr [...]
SPAC56F8.07 protein networkhttps://string-db.org/network/284812.Q10255Uncharacterized membrane protein SPAC56F8.07.
mud1 protein networkhttps://string-db.org/network/284812.Q10256UBA domain-containing protein Mud1; Recognizes and binds polyubiquitin chains. Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquiti [...]
rrp8 protein networkhttps://string-db.org/network/284812.Q1025725S rRNA (adenine(645)-N(1))-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required b [...]
met9 protein networkhttps://string-db.org/network/284812.Q10258Methylenetetrahydrofolate reductase 1; Major methylenetetrahydrofolate reductase required to generate the methyl groups necessary for methionine synthetase to convert homocysteine to methionine. [...]
spc3 protein networkhttps://string-db.org/network/284812.Q10259Probable microsomal signal peptidase subunit 3; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the [...]
SPAC56F8.12 protein networkhttps://string-db.org/network/284812.Q10260Uncharacterized protein C56F8.12.
SPAC56F8.13 protein networkhttps://string-db.org/network/284812.Q10261Uncharacterized protein C56F8.13.
SPAC56F8.15 protein networkhttps://string-db.org/network/284812.Q10263Uncharacterized protein C56F8.15.
pso2 protein networkhttps://string-db.org/network/284812.Q10264DNA cross-link repair protein pso2/snm1; Required for DNA interstrand cross-link repair. This requires cleavage of cross-linked DNA to generate DNA double strand breaks (DSBs). This protein may h [...]
ssa1 protein networkhttps://string-db.org/network/284812.Q10265Probable heat shock protein ssa1.
upf3 protein networkhttps://string-db.org/network/284812.Q10267Nonsense-mediated mRNA decay protein 3; Involved in nonsense-mediated decay of mRNAs containing premature stop codons; Belongs to the RENT3 family.
mac1 protein networkhttps://string-db.org/network/284812.Q10268Membrane-anchored protein 1; Required for correct cell separation at high temperatures; To yeast YOL019W and YMR063W.
are1 protein networkhttps://string-db.org/network/284812.Q10269Probable sterol O-acyltransferase 1.
met16 protein networkhttps://string-db.org/network/284812.Q10270Probable phosphoadenosine phosphosulfate reductase; The NADP dependent reduction of PAPS into sulfite involves thioredoxin which probably plays the role of a thiol carrier (By similarity). Requir [...]
arb2 protein networkhttps://string-db.org/network/284812.Q10271Argonaute-binding protein 2; A member of the argonaute siRNA chaperone (ARC) complex which is required for histone H3K9 methylation, heterochromatin assembly and siRNA generation. The ARC complex [...]
crb3 protein networkhttps://string-db.org/network/284812.Q10272Pre-rRNA-processing protein crb3/ipi3; Required for both pre-rRNA processing and heterochromatic gene silencing; Belongs to the WD repeat IPI3/WDR18 family.
teb1 protein networkhttps://string-db.org/network/284812.Q10274Telobox protein 1; General transcription factor with prominent roles in controlling histone levels and stability. Binds and regulates the activities of many promoters, including those controlling [...]
mba1 protein networkhttps://string-db.org/network/284812.Q10275Uncharacterized protein C13G7.11.
eki1 protein networkhttps://string-db.org/network/284812.Q10276Putative choline kinase; Belongs to the choline/ethanolamine kinase family.
msa1 protein networkhttps://string-db.org/network/284812.Q10277Multicopy suppressor of sporulation protein msa1; Negative regulator of sexual differentiation. Acts by repressing the transcription of meiosis-inducing, ste11-regulated genes.
fur4 protein networkhttps://string-db.org/network/284812.Q10279Uracil permease; Transport of uracil; Belongs to the purine-cytosine permease (2.A.39) family.
gaf1 protein networkhttps://string-db.org/network/284812.Q10280Transcription factor gaf1; Transcriptional activator.
cpc2 protein networkhttps://string-db.org/network/284812.Q10281Guanine nucleotide-binding protein subunit beta-like protein; May be a receptor for protein kinase C in the regulation of actin cytoskeleton organization during cell wall synthesis and morphogene [...]
git5 protein networkhttps://string-db.org/network/284812.Q10282Guanine nucleotide-binding protein subunit beta; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta an [...]
hmg1 protein networkhttps://string-db.org/network/284812.Q102833-hydroxy-3-methylglutaryl-coenzyme A reductase; Catalyzes the conversion of HMG-CoA to mevalonate. It is the rate-limiting enzyme of the sterol biosynthesis pathway. Involved in ergosterol biosy [...]
sks2 protein networkhttps://string-db.org/network/284812.Q10284Ribosome-associated molecular chaperone sks2; Ribosome-bound, Hsp70-type chaperone that assists in the cotranslational folding of newly synthesized proteins in the cytosol. Stimulates folding by [...]
itr1 protein networkhttps://string-db.org/network/284812.Q10286Myo-inositol transporter 1; Transporter for myo-inositol.
bgs1 protein networkhttps://string-db.org/network/284812.Q102871,3-beta-glucan synthase component bgs1; Required for the assembly of the division septum and maintenance of cell polarity.
fas2 protein networkhttps://string-db.org/network/284812.Q102893-oxoacyl-[acyl-carrier-protein] reductase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The alpha subunit contains domains for: [...]
mal2 protein networkhttps://string-db.org/network/284812.Q10290Inner kinetochore subunit mal2; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segre [...]
mek1 protein networkhttps://string-db.org/network/284812.Q10292Meiosis-specific serine/threonine-protein kinase mek1; Probable protein kinase required for meiotic recombination.
pac2 protein networkhttps://string-db.org/network/284812.Q10294cAMP-independent regulatory protein pac2; Controls the onset of sexual development, by inhibiting the expression of ste11, in a pathway that is independent of the cAMP cascade.
pla1 protein networkhttps://string-db.org/network/284812.Q10295Poly(A) polymerase pla1; Polymerase that creates the 3'-poly(A) tail of mRNA's. May acquire specificity through interaction with a cleavage and polyadenylation factor (CF I).
kap114 protein networkhttps://string-db.org/network/284812.Q10297Importin subunit beta-5; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. Serves a receptor for nuclear localization signals. Mediates the nu [...]
ppa3 protein networkhttps://string-db.org/network/284812.Q10298Putative serine/threonine-protein phosphatase C22H10.04.
SPAC22H10.05c protein networkhttps://string-db.org/network/284812.Q10299mRNA cleavage and polyadenylation factor clp1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.
cbp8 protein networkhttps://string-db.org/network/284812.Q10302Uncharacterized protein C22H10.09.
alp21 protein networkhttps://string-db.org/network/284812.Q10303Cell polarity protein alp21; Required for microtubule and spindle assembly. Involved in the proper folding of alpha-tubulin.
crf1 protein networkhttps://string-db.org/network/284812.Q10304Uncharacterized protein C22H10.11c.
gdi1 protein networkhttps://string-db.org/network/284812.Q10305Probable secretory pathway GDP dissociation inhibitor 1; Belongs to the Rab GDI family.
cit1 protein networkhttps://string-db.org/network/284812.Q10306Probable citrate synthase, mitochondrial; Belongs to the citrate synthase family.
mix17 protein networkhttps://string-db.org/network/284812.Q10307Uncharacterized protein C6C3.02c.
meu43 protein networkhttps://string-db.org/network/284812.Q10308Meiotically up-regulated gene 43 protein; Has a role in meiosis.
neo1 protein networkhttps://string-db.org/network/284812.Q10309Putative phospholipid-transporting ATPase C6C3.06c; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
nas6 protein networkhttps://string-db.org/network/284812.Q10311Ankyrin repeat-containing protein C6C3.08.
rpp40 protein networkhttps://string-db.org/network/284812.Q10312Uncharacterized protein C6C3.09.
trl1 protein networkhttps://string-db.org/network/284812.Q10313tRNA ligase 1; Required for the splicing of precursor tRNA molecules containing introns. The ligation activity requires three enzymatic activities: phosphorylation of the 5' terminus of the 3' ha [...]
urh2 protein networkhttps://string-db.org/network/284812.Q10314Uncharacterized protein C17G8.02; Belongs to the IUNH family.
bur6 protein networkhttps://string-db.org/network/284812.Q10315Transcription regulator complex subunit bur6; Transcription regulator complex subunit that is essential for cell cycle progression.
arc5 protein networkhttps://string-db.org/network/284812.Q10316Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promot [...]
med20 protein networkhttps://string-db.org/network/284812.Q10317Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
ilv3 protein networkhttps://string-db.org/network/284812.Q10318Putative dihydroxy-acid dehydratase, mitochondrial.
yaf9 protein networkhttps://string-db.org/network/284812.Q10319Protein AF-9 homolog; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by c [...]
gdt2 protein networkhttps://string-db.org/network/284812.Q10320GDT1-like protein C17G8.08c.
shg1 protein networkhttps://string-db.org/network/284812.Q10321Set1 complex component shg1; The Set1 complex specifically methylates 'Lys-4' of histone H3.
dma1 protein networkhttps://string-db.org/network/284812.Q10322Probable E3 ubiquitin-protein ligase dma1; Probable E3 ubiquitin-protein ligase which is a component of the spindle assembly checkpoint, required to prevent septum formation and premature exit fr [...]
imt3 protein networkhttps://string-db.org/network/284812.Q10323Inositol phosphoceramide mannosyltransferase 3; With imt1 and imt2, is required for the synthesis of mannosylinositol phosphoceramide (MIPC). Catalyzes the addition of mannosyl to inositol phosph [...]
sec3 protein networkhttps://string-db.org/network/284812.Q10324Uncharacterized protein C17G8.12.
mst2 protein networkhttps://string-db.org/network/284812.Q10325Histone acetyltransferase mst2; Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3K1 [...]
mug8 protein networkhttps://string-db.org/network/284812.Q10326Meiotically up-regulated gene 8 protein; Has a role in meiosis and septation.
SPAC32A11.02c protein networkhttps://string-db.org/network/284812.Q10327Uncharacterized protein C32A11.02c.
phx1 protein networkhttps://string-db.org/network/284812.Q10328Homeobox transcription factor phx1; Trnascription factor that regulates the expression of the homocitrate synthase (HCS) lys4.
pre6 protein networkhttps://string-db.org/network/284812.Q10329Probable proteasome subunit alpha type-4; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent [...]
rpl2501 protein networkhttps://string-db.org/network/284812.Q1033060S ribosomal protein L25-A; This protein binds to a specific region on the 26S rRNA. Belongs to the universal ribosomal protein uL23 family.
nup107 protein networkhttps://string-db.org/network/284812.Q10331Nucleoporin nup107; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural component [...]
rhp1602 protein networkhttps://string-db.org/network/284812.Q10332Uncharacterized ATP-dependent helicase C582.10c.
pex11 protein networkhttps://string-db.org/network/284812.Q10333Peroxisomal biogenesis factor 11; Involved in peroxisomal proliferation. Promotes peroxisome division and biogenesis (By similarity); Belongs to the peroxin-11 family.
SPBC582.08 protein networkhttps://string-db.org/network/284812.Q10334Putative alanine aminotransferase.
rpn7 protein networkhttps://string-db.org/network/284812.Q10335Probable 26S proteasome regulatory subunit rpn7; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
mcp6 protein networkhttps://string-db.org/network/284812.Q10336Meiotic coiled-coil protein 6; Has a role in meiotic nuclear oscillation and recombination. Required to remodel astral microtubules into the 'horsetail' astral array maintaining the 'horsetail' n [...]
brc1 protein networkhttps://string-db.org/network/284812.Q10337BRCT-containing protein 1; Required for mitotic fidelity, specifically in the G2 phase of the cell cycle. Plays a role in chromatin organization.
dsh1 protein networkhttps://string-db.org/network/284812.Q10338Uncharacterized protein C582.04c.
exo70 protein networkhttps://string-db.org/network/284812.Q10339Exocyst complex component exo70; Required for exocytosis; Belongs to the EXO70 family.
ppr10 protein networkhttps://string-db.org/network/284812.Q10340Uncharacterized protein C106.19.
cys2 protein networkhttps://string-db.org/network/284812.Q10341Serine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine. Has also weak serine acetyl transferase activity and homoserine succinyl transfe [...]
sda1 protein networkhttps://string-db.org/network/284812.Q10342Protein sda1; Required for 60S pre-ribosomal subunits export to the cytoplasm. May also be required for 60S ribosomal subunit maturation and accumulation (By similarity); Belongs to the SDA1 fami [...]
cbs2 protein networkhttps://string-db.org/network/284812.Q103435'-AMP-activated protein kinase subunit gamma; Adenine nucleotides-binding subunit gamma of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulatin [...]
tma19 protein networkhttps://string-db.org/network/284812.Q10344Translationally-controlled tumor protein homolog; Involved in calcium binding and microtubule stabilization (By similarity). May be a guanine nucleotide-free chaperone (GFC). Belongs to the TCTP [...]
SPAC1F12.04c protein networkhttps://string-db.org/network/284812.Q10346Uncharacterized protein C1F12.04c.
any2 protein networkhttps://string-db.org/network/284812.Q10347Uncharacterized protein C1F12.05.
SPAC1F12.06c protein networkhttps://string-db.org/network/284812.Q10348Putative endonuclease C1F12.06c.
ser1 protein networkhttps://string-db.org/network/284812.Q10349Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreoni [...]
cab4 protein networkhttps://string-db.org/network/284812.Q10350Uncharacterized protein C1F12.08; To yeast YGR277c.
gpi17 protein networkhttps://string-db.org/network/284812.Q10351GPI transamidase component PIG-S homolog; Component of the GPI transamidase complex. Involved in transfer of GPI to proteins (By similarity); Belongs to the PIGS family.
SPAC1F12.10c protein networkhttps://string-db.org/network/284812.Q10352Uncharacterized protein C1F12.10c; Belongs to the cytochrome b5 family.
rlp24 protein networkhttps://string-db.org/network/284812.Q10353Ribosome biogenesis protein rlp24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of nog1 to pre-60S particles. Activates and recruits ATPase afg2 to cytoplasmic pre [...]
pet3 protein networkhttps://string-db.org/network/284812.Q10354Uncharacterized transporter C22E12.01.
SPAC22E12.02 protein networkhttps://string-db.org/network/284812.Q10355Uncharacterized RNA-binding protein C22E12.02.
sdj1 protein networkhttps://string-db.org/network/284812.Q10356Glutathione-independent glyoxalase DJ-1; Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step. May play a role in detoxifying endogenously pr [...]
ccs1 protein networkhttps://string-db.org/network/284812.Q10357Superoxide dismutase 1 copper chaperone; Copper chaperone for superoxide dismutase 1 (sod1). Binds copper ions and delivers them specifically to sod1. Also has a role in cell protection against c [...]
rer1 protein networkhttps://string-db.org/network/284812.Q10358Protein rer1.
gmh3 protein networkhttps://string-db.org/network/284812.Q10359Alpha-1,2-galactosyltransferase gmh3; Involved in the galactosylation of the N-linked core oligosaccharide Man(9)GlcNAc(2); Belongs to the glycosyltransferase 34 family.
rrn10 protein networkhttps://string-db.org/network/284812.Q10360RNA polymerase I-specific transcription initiation factor rrn10; Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promot [...]
etp1 protein networkhttps://string-db.org/network/284812.Q10361Electron transfer protein 1, mitochondrial.
set3 protein networkhttps://string-db.org/network/284812.Q10362SET domain-containing protein 3; Transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. Required for both gene activation [...]
sck2 protein networkhttps://string-db.org/network/284812.Q10364Serine/threonine-protein kinase sck2; Protein kinase that is part of growth control pathway which is at least partially redundant with the cAMP pathway.
pik1 protein networkhttps://string-db.org/network/284812.Q10366Phosphatidylinositol 4-kinase pik1; Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,- trisphosphate. PIK1 is part of a nucle [...]
glo3 protein networkhttps://string-db.org/network/284812.Q10367ADP-ribosylation factor GTPase-activating protein glo3; GTPase-activating protein for the ADP ribosylation factor (ARF) family. Involved in retrograde vesicular transport from the Golgi to the en [...]
SPAC22E12.18 protein networkhttps://string-db.org/network/284812.Q10368Uncharacterized protein C22E12.18.
snt1 protein networkhttps://string-db.org/network/284812.Q10369Uncharacterized protein C22E12.19.
mkh1 protein networkhttps://string-db.org/network/284812.Q10407MAP kinase kinase kinase mkh1; May regulate cell morphology, cell wall integrity, salt resistance, cell cycle reentry from stationary-phase arrest, and filamentous growth in response to stress. A [...]
sro7 protein networkhttps://string-db.org/network/284812.Q10408Uncharacterized protein C1F3.03.
tsr3 protein networkhttps://string-db.org/network/284812.Q10409Ribosome biogenesis protein tsr3; Ribosome biogenesis protein required for processing 35S pre- rRNA at site D; Belongs to the TSR3 family.
gga21 protein networkhttps://string-db.org/network/284812.Q10410Probable ADP-ribosylation factor-binding protein C1F3.05; May play a role in the regulation of membrane traffic through the trans-Golgi network.
spo15 protein networkhttps://string-db.org/network/284812.Q10411Sporulation-specific protein 15; Has a role in the initiation of spore membrane formation.
rsc58 protein networkhttps://string-db.org/network/284812.Q10412Chromatin structure-remodeling complex subunit rsc58; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Cont [...]
mug161 protein networkhttps://string-db.org/network/284812.Q10414CWF19-like protein mug161; Has a role in meiosis; Belongs to the CWF19 family.
oct1 protein networkhttps://string-db.org/network/284812.Q10415Mitochondrial intermediate peptidase; Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one [...]
SPAC25G10.01 protein networkhttps://string-db.org/network/284812.Q10422Uncharacterized RNA-binding protein C25G10.01.
cce1 protein networkhttps://string-db.org/network/284812.Q10423Cruciform cutting endonuclease 1, mitochondrial; Capable of resolving Holliday junctions. Specific for 4-way junctions. Seems to be important for the maintenance of mitochondrial DNA. Cleaves fix [...]
zip1 protein networkhttps://string-db.org/network/284812.Q10424Transcription factor zip1; Mediates cell growth arrest in response to cadmium exposure, which is essential to maintain cell viability. Regulates cadmium stress specific genes; Belongs to the bZIP [...]
tif302 protein networkhttps://string-db.org/network/284812.Q10425Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a speciali [...]
rik1 protein networkhttps://string-db.org/network/284812.Q10426Chromatin modification-related protein rik1; Component of the rik1-associated E3 ubiquitin ligase complex that shows ubiquitin ligase activity and is required for histone H3K9 methylation. H3K9me [...]
SPCC11E10.09c protein networkhttps://string-db.org/network/284812.Q10427Uncharacterized glycosyl hydrolase C11E10.09c.
par1 protein networkhttps://string-db.org/network/284812.Q10428Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta 1 isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the [...]
cnd3 protein networkhttps://string-db.org/network/284812.Q10429Condensin complex subunit 3; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex p [...]
spc25 protein networkhttps://string-db.org/network/284812.Q10430Kinetochore protein spc25; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cyc [...]
ccq1 protein networkhttps://string-db.org/network/284812.Q10432Coiled-coil quantitatively-enriched protein 1; Component of the meiotic bouquet that facilitates meiotic nuclear reorganization of the telomeres to the centrosome. Links telomeres to the meiotic [...]
acp1 protein networkhttps://string-db.org/network/284812.Q10434F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subun [...]
SPAC12B10.01c protein networkhttps://string-db.org/network/284812.Q10435Probable ubiquitin fusion degradation protein C12B10.01c; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly [...]
pho86 protein networkhttps://string-db.org/network/284812.Q10436Uncharacterized protein C12B10.02c.
bun62 protein networkhttps://string-db.org/network/284812.Q10437UBP9-binding protein bun62; Required for the ubp9 recruitment to septa and cell tips but also for its enzymatic activity at these specific locations.
pby1 protein networkhttps://string-db.org/network/284812.Q10438Probable tubulin--tyrosine ligase C12B10.04; Probable tubulin--tyrosine ligase.
icp55 protein networkhttps://string-db.org/network/284812.Q10439Intermediate cleaving peptidase 55; Aminopeptidase which cleaves preprotein intermediates that carry destabilizing N-ter amino acid residues after the mitochondrial processing peptidase (MPP) cle [...]
emi5 protein networkhttps://string-db.org/network/284812.Q10440Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) [...]
til1 protein networkhttps://string-db.org/network/284812.Q10441Probable tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cyti [...]
pet801 protein networkhttps://string-db.org/network/284812.Q10442Uncharacterized mitochondrial carrier C12B10.09.
nod1 protein networkhttps://string-db.org/network/284812.Q10443Uncharacterized protein C12B10.10.
exg2 protein networkhttps://string-db.org/network/284812.Q10444Glucan 1,3-beta-glucosidase 2; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
rhp41 protein networkhttps://string-db.org/network/284812.Q10445DNA repair protein rhp41; Has a role in the nucleotide excision repair (NER) pathway. Acts in both transcription-coupled repair (TCR) which removes damage from the transcribed strand of active ge [...]
gid8 protein networkhttps://string-db.org/network/284812.Q10446Uncharacterized protein C12B10.13.
tea5 protein networkhttps://string-db.org/network/284812.Q10447Protein kinase domain-containing protein ppk2.
rnh203 protein networkhttps://string-db.org/network/284812.Q10448Uncharacterized protein C12B10.15c.
mug157 protein networkhttps://string-db.org/network/284812.Q10449Meiotically up-regulated gene 157 protein; Has a role in meiosis.
ppr5 protein networkhttps://string-db.org/network/284812.Q10451Pentatricopeptide repeat-containing protein 5, mitochondrial; Mitochondrial RNA-binding protein that acts as a general negative regulator of mitochondrial translation.
gsk3 protein networkhttps://string-db.org/network/284812.Q10452Protein kinase gsk3; Interacts with cdc14 which is thought to play a role in the initiation and completion of mitosis. Involved in the positive regulation of mis12.
lys7 protein networkhttps://string-db.org/network/284812.Q10474L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; Catalyzes the transfer of a 4'-phosphopantetheine moiety from coenzyme A to a serine residue of acceptor proteins, such [...]
tif471 protein networkhttps://string-db.org/network/284812.Q10475Eukaryotic translation initiation factor 4 gamma; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary st [...]
pmc3 protein networkhttps://string-db.org/network/284812.Q10477Mediator of RNA polymerase II transcription subunit 27; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
sam50 protein networkhttps://string-db.org/network/284812.Q10478SAM50-like protein SPAC17C9.06; May be required for the assembly pathway of mitochondrial outer membrane proteins; Belongs to the SAM50/omp85 family.
alg8 protein networkhttps://string-db.org/network/284812.Q10479Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose f [...]
pnu1 protein networkhttps://string-db.org/network/284812.Q10480Nuclease 1, mitochondrial; This enzyme has both RNase and DNase activity. It degrades single-stranded DNA and RNA.
tim13 protein networkhttps://string-db.org/network/284812.Q10481Mitochondrial import inner membrane translocase subunit tim13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into t [...]
stm1 protein networkhttps://string-db.org/network/284812.Q10482Seven transmembrane protein 1; To yeast YBR147w and SpAC2E12.03c.
SPAC17C9.11c protein networkhttps://string-db.org/network/284812.Q10483Uncharacterized protein C17C9.11c.
scs22 protein networkhttps://string-db.org/network/284812.Q10484Uncharacterized protein C17C9.12.
pex19 protein networkhttps://string-db.org/network/284812.Q10485Uncharacterized protein C17C9.14.
mfs1 protein networkhttps://string-db.org/network/284812.Q10487Transporter mfs1.
etr1 protein networkhttps://string-db.org/network/284812.Q10488Enoyl-[acyl-carrier-protein] reductase, mitochondrial; Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fa [...]
pda1 protein networkhttps://string-db.org/network/284812.Q10489Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple cop [...]
lrs1 protein networkhttps://string-db.org/network/284812.Q10490Putative leucine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
sec74 protein networkhttps://string-db.org/network/284812.Q10491Arf guanine nucleotide exchange factor sec74; Guanine nucleotide exchange factor for Arf GTPases, stimulating the nucleotide exchange from the GDP-bound to the GTP-bound form. Involved in vesicul [...]
pnn1 protein networkhttps://string-db.org/network/284812.Q10492Pinin homolog 1; Transcriptional activator that may participate in the regulation of mRNA splicing; Belongs to the pinin family.
mug106 protein networkhttps://string-db.org/network/284812.Q10493Meiotically up-regulated gene 106 protein; Has a role in meiosis.
SPAC26F1.07 protein networkhttps://string-db.org/network/284812.Q10494Uncharacterized oxidoreductase C26F1.07; Belongs to the aldo/keto reductase family.
SPAC26F1.08c protein networkhttps://string-db.org/network/284812.Q10495Uncharacterized protein C26F1.08c.
gyp51 protein networkhttps://string-db.org/network/284812.Q10496GTPase activating protein Gyp51; GTPase-activating protein involved in ER to Golgi trafficking and polarized exocytosis; Belongs to the GYP5 family.
hgh1 protein networkhttps://string-db.org/network/284812.Q10498Protein HGH1 homolog; Belongs to the HGH1 family.
aif1 protein networkhttps://string-db.org/network/284812.Q10499Apoptosis-inducing factor 1; Putative FAD-dependent oxidoreductase involved in the resistance to cercosporin and other singlet oxygen-generating photosensitizers. Translocates from mitochondria t [...]
spd1 protein networkhttps://string-db.org/network/284812.Q10585S-phase delaying protein 1; Regulates the ribonucleotide reductase activity through its mediation of the nuclear localization of suc22, the small subunit of the ribonucleotide reductase. Delays t [...]
spo14 protein networkhttps://string-db.org/network/284812.Q10659Membrane glycoprotein spo14; Required for the formation of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the smal [...]
swi2 protein networkhttps://string-db.org/network/284812.Q10668Mating-type switching protein swi2; Required for normal mating-type switching.
fus1 protein networkhttps://string-db.org/network/284812.Q10719Cell fusion protein fus1; Required for cell fusion. It associates with the pre-zygotic projection tips in conjugating cells; Belongs to the formin homology family. BNI1 subfamily.
cdc28 protein networkhttps://string-db.org/network/284812.Q10752Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein cdc28; Involved in pre-mRNA splicing. Is required together with ATP and at least one other factor, for the first cleavage-ligation [...]
byr4 protein networkhttps://string-db.org/network/284812.Q10951Protein byr4; Has an essential role in ensuring cytokinesis and septation occur only once during mitosis. It does so by interacting with the ras1 signaling pathways, thereby suppressing them; To [...]
uve1 protein networkhttps://string-db.org/network/284812.Q10988UV-damage endonuclease; Endonuclease for the repair of UV-irradiated DNA. Involved in the excision of cyclobutane pyrimidine dimers (CPD) and 6-4 pyrimidine pyrimidones (6-4PP) which forms the UV [...]
cdt2 protein networkhttps://string-db.org/network/284812.Q10990Cell division cycle protein cdt2; Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for DNA replication during mitosis and meiosis. The DCX(DTL) c [...]
wis2 protein networkhttps://string-db.org/network/284812.Q1100440 kDa peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); [...]
wos2 protein networkhttps://string-db.org/network/284812.Q11118Protein wos2; Cell cycle regulatory protein that interacts with cdc2 in the control of the M-G1 transition.
ubp14 protein networkhttps://string-db.org/network/284812.Q11119Ubiquitin carboxyl-terminal hydrolase 14.
ofd1 protein networkhttps://string-db.org/network/284812.Q11120Prolyl 3,4-dihydroxylase ofd1; Prolyl 3,4-dihydroxylase that catalyzes 3,4-dihydroxylation of 'Pro-62' of small ribosomal subunit uS12 (rps23 and rps2302), thereby regulating protein translation [...]
mcs6 protein networkhttps://string-db.org/network/284812.Q12126Serine/threonine-protein kinase crk1; Protein kinase essential for cell proliferation, where it is required for completion of cytokinesis. Phosphorylates the C-terminal repeat domain (CTD) of RNA [...]
uvi31 protein networkhttps://string-db.org/network/284812.Q12238UV-induced protein uvi31; May be involved in control of cell division, especially during the resumption from cell cycle arrest; Belongs to the BolA/IbaG family.
prp1 protein networkhttps://string-db.org/network/284812.Q12381Pre-mRNA-splicing factor prp1; Involved in pre-mRNA splicing. Interacts with prp6 and prp13. May also be involved in the regulation of the G0-G1/G2 transition. Required for pre-spliceosome format [...]
ksg1 protein networkhttps://string-db.org/network/284812.Q12701Serine/threonine-protein kinase ksg1; Involved in the control of sexual development and cell growth under stressed conditions. Phosphorylates AGC kinase gad8 at 'Thr-387', activating gad8 kinase [...]
pab1 protein networkhttps://string-db.org/network/284812.Q12702Protein phosphatase PP2A regulatory subunit B; Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellular morphogenesis, and p [...]
pog1 protein networkhttps://string-db.org/network/284812.Q12704DNA polymerase gamma; Involved in the replication of mitochondrial DNA.
ppb1 protein networkhttps://string-db.org/network/284812.Q12705Serine/threonine-protein phosphatase 2B catalytic subunit; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. [...]
psk1 protein networkhttps://string-db.org/network/284812.Q12706Serine/threonine-protein kinase psk1; AGC kinase which plays a role in TOR complex 1 (TORC1) signaling pathway which mediates temporal control of cell growth in response to nutrients. Required fo [...]
sir1 protein networkhttps://string-db.org/network/284812.Q1K9C2Sulfite reductase [NADPH] subunit beta; Catalyzes the reduction of sulfite to sulfide, one of several activities required for the biosynthesis of L-cysteine from sulfate.
hul5 protein networkhttps://string-db.org/network/284812.Q1K9C4Probable E3 ubiquitin protein ligase C167.07c; Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins.
SPAC1327.01c protein networkhttps://string-db.org/network/284812.Q1MTM9Uncharacterized transcriptional regulatory protein C1327.01c.
pic1 protein networkhttps://string-db.org/network/284812.Q1MTN3Inner centromere protein-related protein pic1; Required for chromosome segregation and cytokinesis. Has a role in sister chromatid cohesion and condensation.
rpm1 protein networkhttps://string-db.org/network/284812.Q1MTN7Exoribonuclease II, mitochondrial; Required for intron-independent turnover and processing of mitochondrial RNA. Participates in 3'-mtRNA processing where it hydrolyzes single-stranded RNA or par [...]
acl4 protein networkhttps://string-db.org/network/284812.Q1MTN8Probable assembly chaperone of rpl4; Acts as a chaperone for the L4 ribosomal subunit encoded by rpl4A and rpl4B, required for hierarchical ribosome assembly. Shields ribosomal protein L4 until t [...]
pcf1 protein networkhttps://string-db.org/network/284812.Q1MTN9Chromatin assembly factor 1 subunit rlf2; Acts as a component of chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto replicating DNA in vitro. It performs the first step of [...]
iss9 protein networkhttps://string-db.org/network/284812.Q1MTP1THP3 homolog C2A9.11c; Required for transcription elongation. May also be involved in pre-mRNA splicing (By similarity); Belongs to the THP3 family.
brl1 protein networkhttps://string-db.org/network/284812.Q1MTQ0E3 ubiquitin-protein ligase brl1; E3 ubiquitin-protein ligase which belongs to the histone H2B ubiquitin ligase complex (HULC) which mediates monoubiquitination of histone H2B to form H2BK123ub1. [...]
tea2 protein networkhttps://string-db.org/network/284812.Q1MTQ1Kinesin-like protein tea2; Promotes microtubule growth, possibly through interactions with the microtubule end, and is important for establishing and maintaining polarized growth along the long a [...]
mug89 protein networkhttps://string-db.org/network/284812.Q1MTQ5Meiotically up-regulated gene 89 protein; Has a role in meiosis; Belongs to the CDC50/LEM3 family.
klp9 protein networkhttps://string-db.org/network/284812.Q1MTQ7Kinesin-like motor protein 9; Kinesin-like motor protein involved in anaphase B spindle elongation; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
nip7 protein networkhttps://string-db.org/network/284812.Q1MTQ960S ribosome subunit biogenesis protein nip7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
atp23 protein networkhttps://string-db.org/network/284812.Q1MTR0Mitochondrial inner membrane protease atp23; Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 a [...]
irc3 protein networkhttps://string-db.org/network/284812.Q1MTR1Putative mitochondrial ATP-dependent helicase irc3.
rns1 protein networkhttps://string-db.org/network/284812.Q1MTR2RNA-binding protein with serine-rich domain 1 homolog; Putative component of the spliceosome which enhances the formation of the ATP-dependent A complex of the spliceosome. may participate in mRN [...]
vid27 protein networkhttps://string-db.org/network/284812.Q1MTR3Vacuolar import and degradation protein 27; Has a role in the negative regulation of gluconeogenesis. Required for vacuolar catabolite degradation of fructose-1,6- bisphosphatase (FBPase) (By sim [...]
cti6 protein networkhttps://string-db.org/network/284812.Q1MTR4Putative histone deacetylase complex subunit cti6; Could be a component of the RPD3C(L) histone deacetylase complex (HDAC).
SPBC15C4.06c protein networkhttps://string-db.org/network/284812.Q1MTR5Uncharacterized RING finger membrane protein C15C4.06c.
SPBC16H5.14c protein networkhttps://string-db.org/network/284812.Q1MTR7Uncharacterized oxidoreductase C16H5.14c.
svp26 protein networkhttps://string-db.org/network/284812.Q1MTR8Protein svp26; May play a role in retention of a subset of membrane proteins in the early Golgi compartments; Belongs to the SVP26 family.
utp3 protein networkhttps://string-db.org/network/284812.Q1MTS0Uncharacterized protein C3B8.09.
tlh2 protein networkhttps://string-db.org/network/284812.Q1RKN3ATP-dependent DNA helicase tlh2; Exhibits ATP-dependent 3' to 5' DNA helicase activity and has a role in telomerase-independent telomere maintenance. Represses ade6 at an ectopic site.
SPAC27E2.12 protein networkhttps://string-db.org/network/284812.Q2EEM0Putative uncharacterized protein C27E2.12.
SPBC1347.14c protein networkhttps://string-db.org/network/284812.Q2HQL6Putative uncharacterized protein C1347.14c.
spo5 protein networkhttps://string-db.org/network/284812.Q2L4W6Sporulation-specific protein 5; RNA-binding protein which plays a role in sporulation. Regulates the progression of meiosis I and may function in the vicinity of the Mei2 dot.
SPAC9E9.06c protein networkhttps://string-db.org/network/284812.Q42598Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
fol1 protein networkhttps://string-db.org/network/284812.Q4LB356-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the central section; belongs to the HPPK family.
nse2 protein networkhttps://string-db.org/network/284812.Q4PIR3E3 SUMO-protein ligase nse2; Acts as an E3 ligase mediating SUMO/Smt3 attachment to other proteins. Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classic [...]
emr1 protein networkhttps://string-db.org/network/284812.Q4ZGE1UPF0618 protein C8C9.19.
spc19 protein networkhttps://string-db.org/network/284812.Q50HP3DASH complex subunit spc19; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates [...]
dad4 protein networkhttps://string-db.org/network/284812.Q50HP4DASH complex subunit dad4; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates [...]
nse1 protein networkhttps://string-db.org/network/284812.Q53EK2Non-structural maintenance of chromosomes element 1; Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of [...]
sgf11 protein networkhttps://string-db.org/network/284812.Q5FC18SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcrip [...]
mrpl27 protein networkhttps://string-db.org/network/284812.Q5WRL154S ribosomal protein L27, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL41 family.
ctf8 protein networkhttps://string-db.org/network/284812.Q65ZA6Chromosome transmission fidelity protein 8; Essential for the fidelity of chromosome transmission. Required for the DNA replication block checkpoint. Replication factor C (RFC) complex has an ess [...]
vma9 protein networkhttps://string-db.org/network/284812.Q69Z14V-type proton ATPase subunit e; Subunit of the integral membrane V0 complex of vacuolar ATPase (By similarity). V-ATPase is responsible for acidifying a variety of intracellular compartments in e [...]
nse4 protein networkhttps://string-db.org/network/284812.Q6BDR8Non-structural maintenance of chromosome element 4; Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of i [...]
tbf1 protein networkhttps://string-db.org/network/284812.Q6E434Telomeric DNA-binding factor trf1; Binds the telomeric double-stranded TTACAGG repeat and regulates telomere length.
aar2 protein networkhttps://string-db.org/network/284812.Q6LA53A1 cistron-splicing factor aar2; Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing. Involved in splicing pre-mRNA of the A1 cistron and other g [...]
hob2 protein networkhttps://string-db.org/network/284812.Q6LA55UPF0648 protein C3H5.09c.
SPAC3H5.11 protein networkhttps://string-db.org/network/284812.Q6LA56Uncharacterized kinase C3H5.11.
SPBCPT2R1.02 protein networkhttps://string-db.org/network/284812.Q6MX60Uncharacterized protein CPT2R1.02.
mme1 protein networkhttps://string-db.org/network/284812.Q76PC3Uncharacterized mitochondrial carrier C1442.03; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane.
glm2 protein networkhttps://string-db.org/network/284812.Q76PC4UPF0649 protein C1442.02.
mti3 protein networkhttps://string-db.org/network/284812.Q76PC7Probable translation initiation factor, mitochondrial; May be involved in mitochondrial translation initiation. Belongs to the IF-3 family.
SPCC1223.01 protein networkhttps://string-db.org/network/284812.Q76PD2E3 ubiquitin-protein ligase hel2; Probable ubiquitin-protein ligase involved in the degradation-related ubiquitination of histones. Contributes to the post-translational regulation of histone pro [...]
dbp6 protein networkhttps://string-db.org/network/284812.Q76PD3ATP-dependent RNA helicase dbp6; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
whi2 protein networkhttps://string-db.org/network/284812.Q7LKV1Uncharacterized protein C20H4.08.
sen15 protein networkhttps://string-db.org/network/284812.Q7LKV3Probable tRNA-splicing endonuclease subunit sen15; Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pr [...]
elo1 protein networkhttps://string-db.org/network/284812.Q7LKX0Putative elongation of fatty acids protein 2; May be involved in the synthesis of very long chain fatty acids.
SPBC1289.14 protein networkhttps://string-db.org/network/284812.Q7LKY2Adducin-related protein C1289.14.
xap5 protein networkhttps://string-db.org/network/284812.Q7LKZ5FAM50 family protein C1020.12c.
SPCC1020.13c protein networkhttps://string-db.org/network/284812.Q7LKZ6Probable phospholipase C1020.13c; Probable phospholipase that hydrolyzes phosphatidic acid. Belongs to the PA-PLA1 family.
lvs1 protein networkhttps://string-db.org/network/284812.Q7LKZ7Beige protein homolog 1; May be involved in protein sorting and cell wall formation.
opt3 protein networkhttps://string-db.org/network/284812.Q7LL00Uncharacterized oligopeptide transporter C1840.12.
SPCC1494.01 protein networkhttps://string-db.org/network/284812.Q7LL04UPF0676 protein C1494.01.
msl1 protein networkhttps://string-db.org/network/284812.Q7LL14Probable U2 small nuclear ribonucleoprotein B'; Involved in pre-mRNA splicing. This protein is associated with snRNP U2. It binds stem loop IV of U2 snRNA (By similarity).
sus1 protein networkhttps://string-db.org/network/284812.Q7LL15Transcription and mRNA export factor sus1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required [...]
nsk1 protein networkhttps://string-db.org/network/284812.Q7LL22Kinetochore protein nsk1; Ensures chromosome alignment and accurate chromosome segregation during mitosis. Promotes proper kinetochore-microtubule (k- MT) interactions during anaphase B. The phos [...]
caf16 protein networkhttps://string-db.org/network/284812.Q7Z991ABC transporter domain-containing protein C20G4.01.
sst6 protein networkhttps://string-db.org/network/284812.Q7Z992ESCRT-I complex subunit vps23; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic u [...]
SPBC19G7.18c protein networkhttps://string-db.org/network/284812.Q7Z995Uncharacterized protein C19G7.18c.
pop8 protein networkhttps://string-db.org/network/284812.Q7Z996Probable ribonucleases P protein subunit pop8; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
fig4 protein networkhttps://string-db.org/network/284812.Q7Z9H9Polyphosphoinositide phosphatase; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).
SPBC409.08 protein networkhttps://string-db.org/network/284812.Q7Z9I0Uncharacterized MFS-type transporter SPBC409.08.
pfl4 protein networkhttps://string-db.org/network/284812.Q7Z9I1Putative cell agglutination protein pfl4; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed ; Belon [...]
SPCC663.09c protein networkhttps://string-db.org/network/284812.Q7Z9I2Uncharacterized oxidoreductase C663.09c.
SPCC663.08c protein networkhttps://string-db.org/network/284812.Q7Z9I3Uncharacterized oxidoreductase C663.08c.
osr1 protein networkhttps://string-db.org/network/284812.Q7Z9I4Uncharacterized oxidoreductase C663.06c.
cox1102 protein networkhttps://string-db.org/network/284812.Q86ZU7Cytochrome c oxidase assembly protein cox11-2; Rsm22-2 is involved in mitochondrion-encoded protein synthesis; In the C-terminal section; belongs to the COX11/CtaG family.
rho4 protein networkhttps://string-db.org/network/284812.Q874R1GTP-binding protein rho4; Required for cell separation. Involved in the regulation of the septum degradation during cytokinesis and in the organization of F- actin patches and cytoplasmic microtu [...]
apc2 protein networkhttps://string-db.org/network/284812.Q874R3Anaphase-promoting complex subunit 2; Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through m [...]
pfl3 protein networkhttps://string-db.org/network/284812.Q874R4Putative cell agglutination protein pfl3; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed ; Belon [...]
SPAC1952.04c protein networkhttps://string-db.org/network/284812.Q8J1M8UPF0768 protein C1952.04c; Belongs to the UPF0768 family.
aes1 protein networkhttps://string-db.org/network/284812.Q8NIL3Antisense-enhancing sequence 1; May have isomerase activity (By similarity). Enhances target gene silencing when coexpressed with antisense RNA.
SPAC2F3.18c protein networkhttps://string-db.org/network/284812.Q8NIQ1Uncharacterized membrane protein C2F3.18c.
SPBPB21E7.09 protein networkhttps://string-db.org/network/284812.Q8NKC0Probable L-asparaginase 3; Belongs to the asparaginase 1 family.
cmt2 protein networkhttps://string-db.org/network/284812.Q8NKC1Probable catechol O-methyltransferase 2.
eno102 protein networkhttps://string-db.org/network/284812.Q8NKC2Enolase 1-2.
wtf5 protein networkhttps://string-db.org/network/284812.Q8TF80Uncharacterized protein wtf5.
SPBPB8B6.05c protein networkhttps://string-db.org/network/284812.Q8TFF8Probable L-asparaginase 4; Belongs to the asparaginase 1 family.
fah1 protein networkhttps://string-db.org/network/284812.Q8TFF9Putative amidase PB8B6.03; Belongs to the amidase family.
SPBPB8B6.02c protein networkhttps://string-db.org/network/284812.Q8TFG0Probable urea active transporter 2; Involved in active transport of urea; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
ght7 protein networkhttps://string-db.org/network/284812.Q8TFG1Probable high-affinity hexose transporter ght7.
SPAPB18E9.04c protein networkhttps://string-db.org/network/284812.Q8TFG4Uncharacterized protein PB18E9.04c.
ppk18 protein networkhttps://string-db.org/network/284812.Q8TFG6Serine/threonine-protein kinase ppk18.
trm5 protein networkhttps://string-db.org/network/284812.Q8TFG7tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the [...]
pfl2 protein networkhttps://string-db.org/network/284812.Q8TFG9Putative GPI-anchored protein pfl2; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed.
SPAPB17E12.14c protein networkhttps://string-db.org/network/284812.Q8TFH0Probable 6-phosphofructo-2-kinase PB17E12.14c; Synthesis of fructose 2,6-bisphosphate.
rpl1802 protein networkhttps://string-db.org/network/284812.Q8TFH160S ribosomal protein L18-B.
mrx21 protein networkhttps://string-db.org/network/284812.Q8TFH2Uncharacterized mitochondrial carrier PB17E12.12c.
ost3 protein networkhttps://string-db.org/network/284812.Q8TFH3Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Ma [...]
mrm202 protein networkhttps://string-db.org/network/284812.Q8TFH4Putative ribosomal RNA methyltransferase PB17E12.10c.
SPAPB17E12.09 protein networkhttps://string-db.org/network/284812.Q8TFH5Meiotically up-regulated protein PB17E12.09; Has a role in meiosis and sporulation.
eos1 protein networkhttps://string-db.org/network/284812.Q8TFH6N-glycosylation protein eos1; Involved in N-glycosylation; Belongs to the EOS1 family.
sen2 protein networkhttps://string-db.org/network/284812.Q8TFH7Probable tRNA-splicing endonuclease subunit sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of [...]
pex12 protein networkhttps://string-db.org/network/284812.Q8TFH8Peroxisome assembly protein 12; Required for protein import into peroxisomes.
loc1 protein networkhttps://string-db.org/network/284812.Q8TFI0Uncharacterized protein C1751.04.
thf1 protein networkhttps://string-db.org/network/284812.Q8WZJ7C-1-tetrahydrofolate synthase, cytoplasmic; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family.
rpc31 protein networkhttps://string-db.org/network/284812.Q8WZJ8DNA-directed RNA polymerase III subunit rpc31; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific periphe [...]
hut1 protein networkhttps://string-db.org/network/284812.Q8WZJ9UDP-galactose transporter homolog 1; May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen (By similarity). Involved in the maintenance of optimal conditions for th [...]
usp107 protein networkhttps://string-db.org/network/284812.Q8WZK0U1 snRNP-associated protein usp107; Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the splice [...]
mrp21 protein networkhttps://string-db.org/network/284812.Q8WZK137S ribosomal protein mrp21, mitochondrial; Belongs to the bacterial ribosomal protein bS21 family.
its8 protein networkhttps://string-db.org/network/284812.Q8WZK2GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4- [...]
ibp1 protein networkhttps://string-db.org/network/284812.Q8WZK3Dual specificity phosphatase ibp1; May play a role in DNA replication checkpoint via regulation of hsk1 or may act downstream of hsk1 in an S phase regulatory pathway.
dcn1 protein networkhttps://string-db.org/network/284812.Q8WZK4Defective in cullin neddylation protein 1; May contribute to neddylation of cullin components of SCF- type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regu [...]
aly1 protein networkhttps://string-db.org/network/284812.Q8WZK5Putative arrestin-related trafficking adapter SPBC839.02; May regulate endocytosis in response to extracellular stimuli.
sdu1 protein networkhttps://string-db.org/network/284812.Q8X1T0DeSI-like protein sdu1; Has a role in meiosis; Belongs to the DeSI family.
abc1 protein networkhttps://string-db.org/network/284812.Q92337ATP-binding cassette transporter abc1.
coq8 protein networkhttps://string-db.org/network/284812.Q92338Protein ABC1 homolog, mitochondrial.
ght3 protein networkhttps://string-db.org/network/284812.Q92339High-affinity gluconate transporter ght3; High-affinity gluconate transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
shu1 protein networkhttps://string-db.org/network/284812.Q92340Uncharacterized GPI-anchored protein C1F8.02c.
str3 protein networkhttps://string-db.org/network/284812.Q92341Siderophore iron transporter 3; Involved in the transport of siderophore iron and so has a role in iron homeostasis; Belongs to the major facilitator superfamily.
SPAC1F8.04c protein networkhttps://string-db.org/network/284812.Q92342Uncharacterized protein C1F8.04c; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
pfl8 protein networkhttps://string-db.org/network/284812.Q92344Putative cell agglutination protein pfl8; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed.
pdc101 protein networkhttps://string-db.org/network/284812.Q92345Probable pyruvate decarboxylase C1F8.07c; Belongs to the TPP enzyme family.
nop9 protein networkhttps://string-db.org/network/284812.Q92347Nucleolar protein 9; RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity); Belongs to the NOP [...]
mug183 protein networkhttps://string-db.org/network/284812.Q92348Meiotically up-regulated gene 183 protein; Has a role in meiosis.
spo7 protein networkhttps://string-db.org/network/284812.Q92349Meiotically up-regulated gene 79 protein; Appears to have a role in sporulation.
pcd1 protein networkhttps://string-db.org/network/284812.Q92350Probable nudix hydrolase C6G9.05; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily.
pcp1 protein networkhttps://string-db.org/network/284812.Q92351Spindle pole body protein pcp1; Spindle pole body component that binds calmodulin. Overexpression of pcp1 causes the formation of supernumerary SPB-like structures and disrupts both mitotic spind [...]
arc4 protein networkhttps://string-db.org/network/284812.Q92352Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nuc [...]
ubp6 protein networkhttps://string-db.org/network/284812.Q92353Ubiquitin carboxyl-terminal hydrolase 6; Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that [...]
rpl2401 protein networkhttps://string-db.org/network/284812.Q9235460S ribosomal protein L24-A.
sen1 protein networkhttps://string-db.org/network/284812.Q92355Helicase sen1; ATP-dependent 5'->3' DNA/RNA helicase required for the expression and maturation of diverse classes of non-protein-coding RNAs like precursor tRNAs, rRNAs and small nuclear (snRNA) [...]
syb1 protein networkhttps://string-db.org/network/284812.Q92356Synaptobrevin homolog 1; Involved in membrane trafficking during cytokinesis and cell elongation; Belongs to the synaptobrevin family.
cfr1 protein networkhttps://string-db.org/network/284812.Q92357Cell fusion protein cfr1; Required for cell fusion, independently of fus1. Appears to have a role in transporting proteins that are involved in mating. May act as a scaffold to retain cell fusion [...]
bqt1 protein networkhttps://string-db.org/network/284812.Q92358Telomere bouquet protein 1; Involved in chromosome segregation. During meiotic prophase, connects telomeres to the spindle pole body by forming a bridge between the telomere protein rap1 and the [...]
puf4 protein networkhttps://string-db.org/network/284812.Q92359Pumilio domain-containing protein C6G9.14.
ebp1 protein networkhttps://string-db.org/network/284812.Q92360Uncharacterized protein C6G9.15c.
xrc4 protein networkhttps://string-db.org/network/284812.Q92361Uncharacterized protein C6G9.16c.
SPAC31G5.21 protein networkhttps://string-db.org/network/284812.Q92363Uncharacterized protein C31G5.21.
rpl3601 protein networkhttps://string-db.org/network/284812.Q9236560S ribosomal protein L36-A.
rpl29 protein networkhttps://string-db.org/network/284812.Q9236660S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family.
SPBC1652.02 protein networkhttps://string-db.org/network/284812.Q92367Amino-acid permease 1.
rcd1 protein networkhttps://string-db.org/network/284812.Q92368Cell differentiation protein rcd1; A differentiation-controlling factor that is essential for the onset of sexual development. Induces ste11 when sexual development is invoked through nitrogen st [...]
trp1 protein networkhttps://string-db.org/network/284812.Q92370Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribo [...]
btf3 protein networkhttps://string-db.org/network/284812.Q92371Nascent polypeptide-associated complex subunit beta; Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polyp [...]
ssb1 protein networkhttps://string-db.org/network/284812.Q92372Replication factor A protein 1; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombinatio [...]
ssb2 protein networkhttps://string-db.org/network/284812.Q92373Replication factor A protein 2; Binds to single-stranded sequences; Belongs to the replication factor A protein 2 family.
ssb3 protein networkhttps://string-db.org/network/284812.Q92374Replication factor A protein 3; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombinatio [...]
trr1 protein networkhttps://string-db.org/network/284812.Q92375Thioredoxin reductase.
pkl1 protein networkhttps://string-db.org/network/284812.Q92376Kinesin-like protein 1; Microtubule-dependent motor that is involved in microtubule organization in the mitotic spindle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin fam [...]
mdm12 protein networkhttps://string-db.org/network/284812.Q92377Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components [...]
rec11 protein networkhttps://string-db.org/network/284812.Q92380Meiotic recombination protein rec11.
mag1 protein networkhttps://string-db.org/network/284812.Q92383DNA-3-methyladenine glycosylase 1; Hydrolysis of the deoxyribose N-glycosidic bond to excise 3- methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions. Can rel [...]
pmk1 protein networkhttps://string-db.org/network/284812.Q92398Mitogen-activated protein kinase spm1; Regulates cell integrity and functions coordinately with the protein kinase C pathway (pck1 and pck2). Involved the regulation of wall architecture, cell sh [...]
rpb8 protein networkhttps://string-db.org/network/284812.Q92399DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Com [...]
pub1 protein networkhttps://string-db.org/network/284812.Q92462E3 ubiquitin-protein ligase pub1; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin [...]
rap1 protein networkhttps://string-db.org/network/284812.Q96TL7DNA-binding protein rap1; Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE). Unlike yeast, exhibits no effect in transcription re [...]
rif1 protein networkhttps://string-db.org/network/284812.Q96UP3Telomere length regulator protein rif1; Negatively regulates telomere length. Appears to play no role in transcriptional silencing of telomeric loci.
SPBC16G5.19 protein networkhttps://string-db.org/network/284812.Q96VG0Uncharacterized protein C16G5.19.
mdm35 protein networkhttps://string-db.org/network/284812.Q96VG1Uncharacterized protein C119.18; Belongs to the TRIAP1/MDM35 family.
ost4 protein networkhttps://string-db.org/network/284812.Q96VG2Probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase 4 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined gly [...]
wtf11 protein networkhttps://string-db.org/network/284812.Q96WS1Meiotic expression up-regulated protein 24.
SPCPB16A4.06c protein networkhttps://string-db.org/network/284812.Q96WU9Uncharacterized protein PB16A4.06c.
ure7 protein networkhttps://string-db.org/network/284812.Q96WV0Uncharacterized urease accessory protein ureG-like; Probably facilitates nickel incorporation; Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
trm8 protein networkhttps://string-db.org/network/284812.Q96WV1tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
opy1 protein networkhttps://string-db.org/network/284812.Q96WV2Uncharacterized PH domain-containing protein PB16A4.02c.
SPBPJ4664.05 protein networkhttps://string-db.org/network/284812.Q96WV4UPF0641 membrane protein PJ4664.05.
cop1 protein networkhttps://string-db.org/network/284812.Q96WV5Putative coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediat [...]
SPBPJ4664.02 protein networkhttps://string-db.org/network/284812.Q96WV6Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02.
cdk9 protein networkhttps://string-db.org/network/284812.Q96WV9Probable cyclin-dependent kinase 9; Component of the positive transcription elongation factor b (P-TEFb) which consists of cdk9 and pch1, and which phosphorylates the C-terminal domain (CTD) of R [...]
wdr8 protein networkhttps://string-db.org/network/284812.Q96WW0Uncharacterized WD repeat-containing protein C32H8.09.
omh5 protein networkhttps://string-db.org/network/284812.Q96WW1O-glycoside alpha-1,2-mannosyltransferase homolog 5; Probable mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins; Belongs to the glycosyltransferase 15 family.
mug93 protein networkhttps://string-db.org/network/284812.Q96WW2Meiotically up-regulated gene 93 protein; Has a role in meiosis.
SPBC32H8.05 protein networkhttps://string-db.org/network/284812.Q96WW3UPF0642 protein C32H8.05.
ivn1 protein networkhttps://string-db.org/network/284812.Q96WW4Invasion protein 1; Required for invasive growth; Belongs to the CDC50/LEM3 family.
cog8 protein networkhttps://string-db.org/network/284812.Q96WW5Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function.
alg2 protein networkhttps://string-db.org/network/284812.Q96WW6Alpha-1,3/1,6-mannosyltransferase alg2; Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
mug153 protein networkhttps://string-db.org/network/284812.Q9C0U3Meiotically up-regulated gene 153 protein; Has a role in meiosis.
xks1 protein networkhttps://string-db.org/network/284812.Q9C0U6Xylulose kinase; Belongs to the FGGY kinase family.
vps5 protein networkhttps://string-db.org/network/284812.Q9C0U7Vacuolar protein sorting-associated protein vps5; Required for efficient sporulation target of PtdIns(3)P in vesicle transport required for onset of the forespore membrane formation.
SPCPB1C11.03 protein networkhttps://string-db.org/network/284812.Q9C0U9Uncharacterized transporter PB1C11.03.
SPCPB1C11.02 protein networkhttps://string-db.org/network/284812.Q9C0V0Probable amino-acid permease PB1C11.02.
amt1 protein networkhttps://string-db.org/network/284812.Q9C0V1Ammonium transporter 1; Transporter for ammonium to use as a nitrogen source. Under ammonium limitation acts as an ammonium sensor, generating a signal that leads to pseudohyphal growth; Belongs [...]
SPBPB7E8.01 protein networkhttps://string-db.org/network/284812.Q9C0V5Uncharacterized protein PB7E8.01.
SPBPB10D8.02c protein networkhttps://string-db.org/network/284812.Q9C0V7Uncharacterized sulfatase PB10D8.02c; Belongs to the sulfatase family.
SPBPB10D8.01 protein networkhttps://string-db.org/network/284812.Q9C0V8Uncharacterized transporter PB10D8.01.
SPBC32H8.01c protein networkhttps://string-db.org/network/284812.Q9C0V9UPF0589 protein C32H8.01c; Belongs to the UPF0589 family.
mis15 protein networkhttps://string-db.org/network/284812.Q9C0W0Inner kinetochore subunit mis15; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segr [...]
nrk1 protein networkhttps://string-db.org/network/284812.Q9C0W1Nicotinamide riboside kinase; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleo [...]
abo2 protein networkhttps://string-db.org/network/284812.Q9C0W2Uncharacterized AAA domain-containing protein P22H7.05c.
SPBP22H7.04 protein networkhttps://string-db.org/network/284812.Q9C0W3Uncharacterized membrane protein P22H7.04.
SPBC800.14c protein networkhttps://string-db.org/network/284812.Q9C0W5Uncharacterized mitochondrial membrane protein C800.14c.
apl3 protein networkhttps://string-db.org/network/284812.Q9C0W7AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact wi [...]
drp1 protein networkhttps://string-db.org/network/284812.Q9C0W8Protein transport protein tip20; Required for protein transport between the Golgi and the endoplasmic reticulum. May contribute to tethering of coatomer-coated retrograde transport vesicles to th [...]
pfa5 protein networkhttps://string-db.org/network/284812.Q9C0W9Palmitoyltransferase PFA5; Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily.
pac3 protein networkhttps://string-db.org/network/284812.Q9C0X2Uncharacterized protein C16E9.19.
min8 protein networkhttps://string-db.org/network/284812.Q9C0X5Uncharacterized protein PB8E5.10.
rvb1 protein networkhttps://string-db.org/network/284812.Q9C0X6RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange o [...]
rrp12 protein networkhttps://string-db.org/network/284812.Q9C0X8Putative ribosomal RNA-processing protein 12; Required for nuclear export of the ribosomal subunits. Required for maturation of the RNA components of pre-ribosomes (By similarity); Belongs to the [...]
npc2 protein networkhttps://string-db.org/network/284812.Q9C0X9Phosphatidylglycerol/phosphatidylinositol transfer protein; Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol; Belongs to the NPC2 family.
SPAPB2C8.01 protein networkhttps://string-db.org/network/284812.Q9C0Y2Putative cell agglutination protein SPAPB2C8.01; May be involved in agglutination during conjugation or other aspects of colony formation; Belongs to the mam3/map4 family.
agl1 protein networkhttps://string-db.org/network/284812.Q9C0Y4Alpha-glucosidase; Hydrolyzes malto-oligosaccharides, but has a low activity toward soluble starch.
pdr1 protein networkhttps://string-db.org/network/284812.Q9C0Y5ATP-binding cassette transporter pdr1.
SPAPB24D3.08c protein networkhttps://string-db.org/network/284812.Q9C0Y6Zinc-type alcohol dehydrogenase-like protein PB24D3.08c.
SPAPB24D3.07c protein networkhttps://string-db.org/network/284812.Q9C0Y7Uncharacterized protein PB24D3.07c.
SPAPB24D3.06c protein networkhttps://string-db.org/network/284812.Q9C0Y8UPF0613 protein PB24D3.06c.
SPAPB24D3.03 protein networkhttps://string-db.org/network/284812.Q9C0Y9Putative agmatinase 3; Belongs to the arginase family.
SPAPB24D3.02c protein networkhttps://string-db.org/network/284812.Q9C0Z0Uncharacterized amino-acid permease PB24D3.02c.
toe3 protein networkhttps://string-db.org/network/284812.Q9C0Z1Uncharacterized transcriptional regulatory protein PB24D3.01.
slx9 protein networkhttps://string-db.org/network/284812.Q9C0Z3Ribosome biogenesis protein slx9; Involved in ribosome biogenesis. Required for normal pre-rRNA processing in internal transcribed spacer 1 (ITS1) (By similarity). Belongs to the SLX9 family.
dop1 protein networkhttps://string-db.org/network/284812.Q9C0Z4Protein dopey; Involved in cellular morphogenesis. Required for traffic between late Golgi and early endosomes, and for the normal structure and organization of the endoplasmic reticulum (By simi [...]
rps602 protein networkhttps://string-db.org/network/284812.Q9C0Z740S ribosomal protein S6-B.
mpa1 protein networkhttps://string-db.org/network/284812.Q9C0Z8Uncharacterized protein PB1E7.11c.
rpc17 protein networkhttps://string-db.org/network/284812.Q9C0Z9DNA-directed RNA polymerase III subunit rpc9; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripher [...]
ogm2 protein networkhttps://string-db.org/network/284812.Q9C100Dolichyl-phosphate-mannose--protein mannosyltransferase 2; Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.
SPAPB1E7.08c protein networkhttps://string-db.org/network/284812.Q9C101Uncharacterized MFS-type transporter PB1E7.08c.
glt1 protein networkhttps://string-db.org/network/284812.Q9C102Putative glutamate synthase [NADPH]; Forms L-glutamate from L-glutamine and 2-oxoglutarate. Represents an alternative pathway to L-glutamate dehydrogenase for the biosynthesis of L-glutamate. Par [...]
eme1 protein networkhttps://string-db.org/network/284812.Q9C103Crossover junction endonuclease eme1; Interacts with mus81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Ty [...]
gde1 protein networkhttps://string-db.org/network/284812.Q9C104Glycerophosphodiester phosphodiesterase gde1; Glycerophosphocholine glycerophosphodiesterase responsible for the hydrolysis of intracellular glycerophosphocholine into glycerol-phosphate and chol [...]
cts2 protein networkhttps://string-db.org/network/284812.Q9C105Chitinase-like protein PB1E7.04c.
rpc82 protein networkhttps://string-db.org/network/284812.Q9C106DNA-directed RNA polymerase III subunit rpc3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core com [...]
mcl1 protein networkhttps://string-db.org/network/284812.Q9C107Minichromosome loss protein 1; Has a role in regulating DNA replication complexes. Acts as a regulator of post DNA replication initiation. Associates with chromatin during G1 and S phases of mito [...]
SPAP27G11.16 protein networkhttps://string-db.org/network/284812.Q9C109Uncharacterized protein P27G11.16.
SPAC343.20 protein networkhttps://string-db.org/network/284812.Q9C111Uncharacterized protein C343.20.
SPAC27F1.10 protein networkhttps://string-db.org/network/284812.Q9C112Uncharacterized membrane protein C27F1.10.
rec25 protein networkhttps://string-db.org/network/284812.Q9C115Meiotic recombination protein rec25; Required for correct meiotic chromosome segregation and recombination.
png3 protein networkhttps://string-db.org/network/284812.Q9C117Uncharacterized protein C16E8.12c.
erg1 protein networkhttps://string-db.org/network/284812.Q9C1W3Probable squalene monooxygenase; Catalyzes the stereospecific oxidation of squalene to (S)- 2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
pmp3 protein networkhttps://string-db.org/network/284812.Q9C1W4Plasma membrane proteolipid 3; Plays a role in the regulation of membrane potential. Could mediate a proton leak. Regulated by the spc1-atf1 pathway and so expression is stress-induced; Belongs t [...]
tim16 protein networkhttps://string-db.org/network/284812.Q9C1W5Mitochondrial import inner membrane translocase subunit tim16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inn [...]
SPBC713.09 protein networkhttps://string-db.org/network/284812.Q9C1W6Uncharacterized protein C713.09.
mim1 protein networkhttps://string-db.org/network/284812.Q9C1W7Mitochondrial import protein 1; Required for the assembly of the TOM (translocase of outer membrane) receptor complex, which is responsible for the recognition and translocation of cytosolically [...]
SPBC713.07c protein networkhttps://string-db.org/network/284812.Q9C1W8Endopolyphosphatase; Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
adl1 protein networkhttps://string-db.org/network/284812.Q9C1W9DNA ligase 3; Belongs to the ATP-dependent DNA ligase family.
wdr83 protein networkhttps://string-db.org/network/284812.Q9C1X0Uncharacterized WD repeat-containing protein C713.05.
pwp2 protein networkhttps://string-db.org/network/284812.Q9C1X1Periodic tryptophan protein 2 homolog; Belongs to the WD repeat PWP2 family.
dld2 protein networkhttps://string-db.org/network/284812.Q9C1X2Putative D-lactate dehydrogenase C713.03, mitochondrial.
bop1 protein networkhttps://string-db.org/network/284812.Q9C1X4Uncharacterized RING finger protein P32A8.03c.
SPAP32A8.02 protein networkhttps://string-db.org/network/284812.Q9C1X5Uncharacterized oxidoreductase P32A8.02.
grt1 protein networkhttps://string-db.org/network/284812.Q9C469Zinc finger protein grt1; May be involved in the facilitation of anaphase progression in mitosis.
SPCP20C8.02c protein networkhttps://string-db.org/network/284812.Q9HDT7UPF0321 protein P20C8.02c; Belongs to the UPF0321 family.
SPCP20C8.01c protein networkhttps://string-db.org/network/284812.Q9HDT8UPF0612 protein P20C8.01c.
SPBPB2B2.18 protein networkhttps://string-db.org/network/284812.Q9HDT9UPF0768 protein PB2B2.18; Belongs to the UPF0768 family.
ftm7 protein networkhttps://string-db.org/network/284812.Q9HDU0UPF0742 protein PB2B2.17c.
SPBPB2B2.14c protein networkhttps://string-db.org/network/284812.Q9HDU1UPF0494 membrane protein PB2B2.14c.
gal1 protein networkhttps://string-db.org/network/284812.Q9HDU2Galactokinase; Belongs to the GHMP kinase family. GalK subfamily.
gal10 protein networkhttps://string-db.org/network/284812.Q9HDU3Bifunctional protein gal10; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity); In the N-termi [...]
tgd1 protein networkhttps://string-db.org/network/284812.Q9HDU4Uncharacterized protein PB2B2.11.
gal7 protein networkhttps://string-db.org/network/284812.Q9HDU5Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
pan5 protein networkhttps://string-db.org/network/284812.Q9HDU6Probable 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
SPBPB2B2.08 protein networkhttps://string-db.org/network/284812.Q9HDU7UPF0643 protein PB2B2.08.
SPBPB2B2.07c protein networkhttps://string-db.org/network/284812.Q9HDU8UPF0494 membrane protein PB2B2.07c.
SPBPB2B2.06c protein networkhttps://string-db.org/network/284812.Q9HDU9Uncharacterized protein PB2B2.06c.
SPBPB2B2.05 protein networkhttps://string-db.org/network/284812.Q9HDV0Putative glutamine amidotransferase PB2B2.05.
say1 protein networkhttps://string-db.org/network/284812.Q9HDV1Putative steryl acetyl hydrolase mug81; Required for the deacetylation of acetylated sterols (By similarity). Has a role in meiosis; Belongs to the 'GDXG' lipolytic enzyme family.
SPBPB2B2.01 protein networkhttps://string-db.org/network/284812.Q9HDV2Uncharacterized amino-acid permease PB2B2.01.
lid2 protein networkhttps://string-db.org/network/284812.Q9HDV4Lid2 complex component lid2.
mrp7 protein networkhttps://string-db.org/network/284812.Q9HDV554S ribosomal protein L27, mitochondrial; Involved in mitochondrial genome encoded proteins translation.
mor2 protein networkhttps://string-db.org/network/284812.Q9HDV6Cell polarity protein mor2; Required for the maintenance of cell polarity. Has a role in localizing F-actin at the cell tips; To yeast TAO3/PAG1.
SPBP19A11.02c protein networkhttps://string-db.org/network/284812.Q9HDV8Uncharacterized protein P19A11.02c.
gcv3 protein networkhttps://string-db.org/network/284812.Q9HDV9Putative glycine cleavage system H protein, mitochondrial; The glycine cleavage system (glycine decarboxylase complex) catalyzes the degradation of glycine. The H protein shuttles the methylamine [...]
toc1 protein networkhttps://string-db.org/network/284812.Q9HDW0Target of rapamycin complex 1 subunit toc1; Component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. Tor2 is essential for grow [...]
pgs1 protein networkhttps://string-db.org/network/284812.Q9HDW1CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol pho [...]
tfb5 protein networkhttps://string-db.org/network/284812.Q9HDW3General transcription and DNA repair factor IIH subunit tfb5; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription [...]
SPAPB2B4.06 protein networkhttps://string-db.org/network/284812.Q9HDW5UPF0644 protein PB2B4.06.
vma5 protein networkhttps://string-db.org/network/284812.Q9HDW6V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a spec [...]
pmc1 protein networkhttps://string-db.org/network/284812.Q9HDW7Calcium-transporting ATPase 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports the calcium to the vacuole and participates in the [...]
grx5 protein networkhttps://string-db.org/network/284812.Q9HDW8Monothiol glutaredoxin-5; Thiol reductase involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for integrity of mitochondrial DNA. May play a crucial [...]
gpi12 protein networkhttps://string-db.org/network/284812.Q9HDW9Probable N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol (By similarity); [...]
mca1 protein networkhttps://string-db.org/network/284812.Q9HDX1Uncharacterized transcriptional regulatory protein PB1A11.04c.
SPAPB1A11.03 protein networkhttps://string-db.org/network/284812.Q9HDX2Uncharacterized lactate 2-monooxygenase PB1A11.03.
SPAPB1A11.02 protein networkhttps://string-db.org/network/284812.Q9HDX3AB hydrolase superfamily protein B1A11.02; Belongs to the AB hydrolase superfamily.
mfc1 protein networkhttps://string-db.org/network/284812.Q9HDX4Uncharacterized transporter mfc1; Belongs to the major facilitator superfamily. CAR1 family.
arv1 protein networkhttps://string-db.org/network/284812.Q9HDX5Protein arv1; Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes. Regulates also the sphingolipid metabolism (By similarity); Belongs to the ARV [...]
pof15 protein networkhttps://string-db.org/network/284812.Q9HDX6F-box protein pof15; Probable substrate recognition component of a SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal d [...]
alo1 protein networkhttps://string-db.org/network/284812.Q9HDX8D-arabinono-1,4-lactone oxidase; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
mse1 protein networkhttps://string-db.org/network/284812.Q9HDX9Glutamate--tRNA ligase, mitochondrial; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the [...]
ypt71 protein networkhttps://string-db.org/network/284812.Q9HDY0GTP-binding protein ypt71.
ase1 protein networkhttps://string-db.org/network/284812.Q9HDY1Anaphase spindle elongation protein 1; Required for anaphase spindle elongation and microtubule bundling in both interphase and mitosis. Has a role in spatial and temporal regulation of septation [...]
SPAPB1A10.07c protein networkhttps://string-db.org/network/284812.Q9HDY3Membrane protein PB1A10.07c.
dhx37 protein networkhttps://string-db.org/network/284812.Q9HDY4Putative ATP-dependent RNA helicase PB1A10.06c; Belongs to the DEAD box helicase family. DEAH subfamily.
SPAPB1A10.05 protein networkhttps://string-db.org/network/284812.Q9HDY5Uncharacterized protein PB1A10.05.
scm3 protein networkhttps://string-db.org/network/284812.Q9HDY7Uncharacterized protein PB1A10.02.
mam3 protein networkhttps://string-db.org/network/284812.Q9HDY9M cell-type agglutination protein mam3; M cell-type specific protein involved in agglutination during conjugation; Belongs to the mam3/map4 family.
SPAP11E10.01 protein networkhttps://string-db.org/network/284812.Q9HDZ0Uncharacterized protein P11E10.01.
cwh43 protein networkhttps://string-db.org/network/284812.Q9HDZ2Protein cwh43; Involved in the maintenance of cell wall integrity. Required for the replacement of the diacylglycerol moiety by ceramides during GPI-anchor maturation (By similarity); In the N-te [...]
pth4 protein networkhttps://string-db.org/network/284812.Q9HDZ3Meiotically up-regulated gene 82 protein; Has a role in meiosis; Belongs to the prokaryotic/mitochondrial release factor family.
dam1 protein networkhttps://string-db.org/network/284812.Q9HDZ6DASH complex subunit dam1; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates [...]
atg1801 protein networkhttps://string-db.org/network/284812.Q9HDZ7Autophagy-related protein 18; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole mor [...]
snd302 protein networkhttps://string-db.org/network/284812.Q9HDZ8Uncharacterized protein C589.06c.
qtr3 protein networkhttps://string-db.org/network/284812.Q9HDZ9Queuosine salvage protein; Involved in salvaging queuosine. Belongs to the queuosine salvage protein family.
mtx2 protein networkhttps://string-db.org/network/284812.Q9HE00Metaxin-1; Involved in transport of proteins into the mitochondrion.
noc12 protein networkhttps://string-db.org/network/284812.Q9HE01Uncharacterized protein C589.03c.
med13 protein networkhttps://string-db.org/network/284812.Q9HE02Mediator of RNA polymerase II transcription subunit 13; Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation [...]
rho5 protein networkhttps://string-db.org/network/284812.Q9HE04GTP-binding protein rho5.
ufd2 protein networkhttps://string-db.org/network/284812.Q9HE05Ubiquitin conjugation factor E4; E4 ubiquitin chain-elongation enzyme specifically involved in polyubiquitin chain assembly. Binds to cdc48 and elongates mono- and diubiquitinated ERAD substrates [...]
SPAC20H4.09 protein networkhttps://string-db.org/network/284812.Q9HE06Putative pre-mRNA-splicing factor ATP-dependent RNA helicase C20H4.09; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA.
gpl1 protein networkhttps://string-db.org/network/284812.Q9HE07Uncharacterized protein C20H4.06c.
mde1 protein networkhttps://string-db.org/network/284812.Q9HE08Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
fml2 protein networkhttps://string-db.org/network/284812.Q9HE09Putative ATP-dependent DNA helicase fml2; Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
dsc3 protein networkhttps://string-db.org/network/284812.Q9HE10DSC E3 ubiquitin ligase complex subunit 3; Component of the DSC E3 ubiquitin ligase complex which is required for the sre1 transcriptional activator proteolytic cleavage to release the soluble tr [...]
utp5 protein networkhttps://string-db.org/network/284812.Q9HE11U3 small nucleolar RNA-associated protein 5; Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a su [...]
SPAC1399.01c protein networkhttps://string-db.org/network/284812.Q9HE12Putative purine permease C1399.01c.
uck2 protein networkhttps://string-db.org/network/284812.Q9HE15Uracil phosphoribosyltransferase 2; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
toe1 protein networkhttps://string-db.org/network/284812.Q9HE16Uncharacterized transcriptional regulatory protein C1399.05c.
tcg1 protein networkhttps://string-db.org/network/284812.Q9HEQ9Single-stranded TG1-3 DNA-binding protein; Binds single-stranded telomeric sequences of the type (TG[1- 3])n in vitro. Has a role in meiosis.
fet4 protein networkhttps://string-db.org/network/284812.Q9HFE1Low-affinity iron/zinc ion transport protein fet4; Required for Fe(2+) ion low affinity uptake (By similarity). Has a role in zinc uptake under conditions of zinc limitation.
fmo1 protein networkhttps://string-db.org/network/284812.Q9HFE4Thiol-specific monooxygenase; Flavin-dependent oxidation of thiol-containing compounds. Probably required for the correct folding of disulfide-bonded proteins (By similarity).
apm1 protein networkhttps://string-db.org/network/284812.Q9HFE5AP-1 complex subunit mu-1; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplas [...]
nop8 protein networkhttps://string-db.org/network/284812.Q9HFE6Uncharacterized RNA-binding protein P16F5.06.
yar1 protein networkhttps://string-db.org/network/284812.Q9HFE7Ankyrin repeat-containing protein P16F5.05c.
tra1 protein networkhttps://string-db.org/network/284812.Q9HFE8Transcription-associated protein 1; Essential component of histone acetyltransferase (HAT) complexes, which serves as a target for activators during recruitment of HAT complexes. Essential for ve [...]
mic10 protein networkhttps://string-db.org/network/284812.Q9HFF0MICOS complex subunit mic10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner mem [...]
SPAC683.02c protein networkhttps://string-db.org/network/284812.Q9HFF2Uncharacterized protein C683.02c.
ppk1 protein networkhttps://string-db.org/network/284812.Q9HFF4Serine/threonine-protein kinase ppk1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
pds5 protein networkhttps://string-db.org/network/284812.Q9HFF5Sister chromatid cohesion protein pds5; Required for the establishment and maintenance of sister chromatid cohesion during S phase. Prevents their formation until eso1 is present. May also have a [...]
csn2 protein networkhttps://string-db.org/network/284812.Q9HFR0COP9 signalosome complex subunit 2; Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cull [...]
meu13 protein networkhttps://string-db.org/network/284812.Q9HGK2Homologous-pairing protein 2; Required for proper homologous pairing and efficient cross- over and intragenic recombination during meiosis. Acts indirectly in a process facilitating homologous re [...]
cnp20 protein networkhttps://string-db.org/network/284812.Q9HGK9Inner kinetochore subunit cnp20; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segr [...]
SPBC800.12c protein networkhttps://string-db.org/network/284812.Q9HGL0Uncharacterized ubiquitin-like protein C800.12c.
SPBC800.11 protein networkhttps://string-db.org/network/284812.Q9HGL1Uncharacterized protein C800.11.
ede1 protein networkhttps://string-db.org/network/284812.Q9HGL2Uncharacterized calcium-binding protein C800.10c.
sum2 protein networkhttps://string-db.org/network/284812.Q9HGL3Protein sum2; Required for G2/M phase checkpoint control.
gcd10 protein networkhttps://string-db.org/network/284812.Q9HGL4tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit trm6; Substrate-binding subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)-methyladenine at [...]
tsf1 protein networkhttps://string-db.org/network/284812.Q9HGL5Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolys [...]
brx1 protein networkhttps://string-db.org/network/284812.Q9HGL6Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family.
rpl4301 protein networkhttps://string-db.org/network/284812.Q9HGL860S ribosomal protein L43-A.
whi5 protein networkhttps://string-db.org/network/284812.Q9HGL9Cell cycle transcriptional repressor whi5; Has a role in meiosis; Belongs to the WHI5/NRM1 family.
get1 protein networkhttps://string-db.org/network/284812.Q9HGM2Protein get1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectiv [...]
yta12 protein networkhttps://string-db.org/network/284812.Q9HGM3Mitochondrial respiratory chain complexes assembly protein rca1; Acts as a component of the m-AAA protease complex which is a ATP-dependent metalloprotease mediating degradation of non-assembled [...]
fit1 protein networkhttps://string-db.org/network/284812.Q9HGM4FIT family protein scs3; May be involved in the synthesis of inositol phospholipids from inositol; Belongs to the FIT family.
dbp8 protein networkhttps://string-db.org/network/284812.Q9HGM5ATP-dependent RNA helicase dbp8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 [...]
bor1 protein networkhttps://string-db.org/network/284812.Q9HGM6Putative transporter C543.05c.
npr3 protein networkhttps://string-db.org/network/284812.Q9HGM7Nitrogen permease regulator 3-like protein; Belongs to the NPR3 family.
pku80 protein networkhttps://string-db.org/network/284812.Q9HGM8ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequenc [...]
SPBC543.02c protein networkhttps://string-db.org/network/284812.Q9HGM9DnaJ homolog subfamily C member 7 homolog.
gcn2 protein networkhttps://string-db.org/network/284812.Q9HGN1eIF-2-alpha kinase GCN2; Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2- alpha/tif211) on 'Ser-52' in response [...]
ccp1 protein networkhttps://string-db.org/network/284812.Q9HGN2Putative nucleosome assembly protein C36B7.08c.
tlg1 protein networkhttps://string-db.org/network/284812.Q9HGN3t-SNARE affecting a late Golgi compartment protein 1.
mug20 protein networkhttps://string-db.org/network/284812.Q9HGN4Meiotically up-regulated gene 20 protein.
pib1 protein networkhttps://string-db.org/network/284812.Q9HGN5Putative E3 ubiquitin-protein ligase C36B7.05c; Functions as an E3 ubiquitin-protein ligase. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate.
dus1 protein networkhttps://string-db.org/network/284812.Q9HGN6tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
sec63 protein networkhttps://string-db.org/network/284812.Q9HGN7Translocation protein sec63; Acts as component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions to [...]
mbx2 protein networkhttps://string-db.org/network/284812.Q9HGP0MADS-box transcription factor pvg4; Acts in transcription regulation. May bind to a MEF2-like typee II promoter sequence.
app1 protein networkhttps://string-db.org/network/284812.Q9HGP1Uncharacterized protein C29B5.04c.
bdf2 protein networkhttps://string-db.org/network/284812.Q9HGP4Bromodomain-containing protein C631.02.
acp2 protein networkhttps://string-db.org/network/284812.Q9HGP5F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subuni [...]
SPAC212.08c protein networkhttps://string-db.org/network/284812.Q9HGP7Uncharacterized GPI-anchored protein C212.08c.
SPAC212.04c protein networkhttps://string-db.org/network/284812.Q9HGP8UPF0494 membrane protein C212.04c.
SPAC212.03 protein networkhttps://string-db.org/network/284812.Q9HGP9Uncharacterized protein C212.03.
SPAC212.02 protein networkhttps://string-db.org/network/284812.Q9HGQ0Uncharacterized protein C212.02.
trm401 protein networkhttps://string-db.org/network/284812.Q9HGQ2Multisite-specific tRNA:(cytosine-C(5))-methyltransferase trm4a; tRNA cytosine C(5)-methyltransferase that methylates cytosine to 5-methylcytosine (m5C) in tRNAs at position 34 and 48. Trm4a and [...]
cis4 protein networkhttps://string-db.org/network/284812.Q9HGQ3Probable zinc transporter cis4; Probable zinc transporter involved in Golgi membrane trafficking through the regulation of zinc homeostasis.
bud20 protein networkhttps://string-db.org/network/284812.Q9P370Zinc finger protein bud20.
sst2 protein networkhttps://string-db.org/network/284812.Q9P371AMSH-like protease sst2; Zinc metalloprotease that specifically cleaves 'Lys-63'- linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role i [...]
srp14 protein networkhttps://string-db.org/network/284812.Q9P372Signal recognition particle subunit srp14; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane.
atg4 protein networkhttps://string-db.org/network/284812.Q9P373Probable cysteine protease atg4; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) [...]
SPAC19B12.07c protein networkhttps://string-db.org/network/284812.Q9P374Zinc finger protein C19B12.07c.
rbd4 protein networkhttps://string-db.org/network/284812.Q9P375Uncharacterized rhomboid protein C19B12.06c.
fcp1 protein networkhttps://string-db.org/network/284812.Q9P376RNA polymerase II subunit A C-terminal domain phosphatase; Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase I [...]
bgs3 protein networkhttps://string-db.org/network/284812.Q9P3771,3-beta-glucan synthase component bgs3; Required for cell wall biosynthesis and cell elongation.
gas1 protein networkhttps://string-db.org/network/284812.Q9P3781,3-beta-glucanosyltransferase gas1; Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan mol [...]
ptr2 protein networkhttps://string-db.org/network/284812.Q9P380Probable peptide transporter ptr2; Uptake of small peptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family.
bbl1 protein networkhttps://string-db.org/network/284812.Q9P381Putative phosphatidate cytidylyltransferase; Supplies CDP-diacylglycerol, which may play an important role as both a precursor to phosphoinositide biosynthesis in the plasma membrane and as a neg [...]
nup82 protein networkhttps://string-db.org/network/284812.Q9P382Nucleoporin nup82; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components [...]
cbc2 protein networkhttps://string-db.org/network/284812.Q9P383Nuclear cap-binding protein subunit 2; Component of the CBC complex, which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in maturation, export and degradation of nuclear [...]
cdc48 protein networkhttps://string-db.org/network/284812.Q9P3A7Cell division cycle protein 48; ATP-dependent chaperone which probably uses the energy provided by ATP hydrolysis to generate mechanical force to unfold substrate proteins, disassemble protein co [...]
knd1 protein networkhttps://string-db.org/network/284812.Q9P3A8Cullin-associated NEDD8-dissociated protein 1; Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate- recognition F-box su [...]
utp8 protein networkhttps://string-db.org/network/284812.Q9P3A9Uncharacterized protein C1565.05.
SPAC1565.03 protein networkhttps://string-db.org/network/284812.Q9P3B0Uncharacterized protein C1565.03.
rga10 protein networkhttps://string-db.org/network/284812.Q9P3B1Putative Rho GTPase-activating protein C1565.02c.
rcf2 protein networkhttps://string-db.org/network/284812.Q9P3B2Respiratory supercomplex factor 2 homolog C1565.01; Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
SPAC750.08c protein networkhttps://string-db.org/network/284812.Q9P3E3NAD-dependent malic enzyme (Predicted), partial.
SPAC750.07c protein networkhttps://string-db.org/network/284812.Q9P3E4Uncharacterized GPI-anchored protein SPAC750.07c.
SPAC750.06c protein networkhttps://string-db.org/network/284812.Q9P3E5UPF0494 membrane protein C750.06c.
ftm4 protein networkhttps://string-db.org/network/284812.Q9P3E6Uncharacterized membrane protein C750.05c.
SPAC750.03c protein networkhttps://string-db.org/network/284812.Q9P3E7Uncharacterized methyltransferase C750.03c; Probable methyltransferase.
rps502 protein networkhttps://string-db.org/network/284812.Q9P3T640S ribosomal protein S5-B.
SPAC328.09 protein networkhttps://string-db.org/network/284812.Q9P3T7Probable mitochondrial 2-oxodicarboxylate carrier; Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria; Belongs to the mitochondrial carrier (TC 2.A.29) family.
tbc1 protein networkhttps://string-db.org/network/284812.Q9P3T8Tubulin-specific chaperone C; Tubulin-folding protein; involved in the final step of the tubulin folding pathway; Belongs to the TBCC family.
bsd1 protein networkhttps://string-db.org/network/284812.Q9P3T9Probable metal homeostasis protein bsd1; Required for homeostasis of heavy metal ions such as cadmium, cobalt and copper; Belongs to the BSD2 family.
ubp2 protein networkhttps://string-db.org/network/284812.Q9P3U0Probable ubiquitin carboxyl-terminal hydrolase 2.
hrb1 protein networkhttps://string-db.org/network/284812.Q9P3U1Uncharacterized RNA-binding protein C328.05.
spg4 protein networkhttps://string-db.org/network/284812.Q9P3U2Uncharacterized AAA domain-containing protein C328.04.
dbl4 protein networkhttps://string-db.org/network/284812.Q9P3U4E3 ubiquitin-protein ligase dbl4; Probable ubiquitin-protein ligase involved in the degradation-related ubiquitination of histones. Contributes to the post-translational regulation of histone pro [...]
ght1 protein networkhttps://string-db.org/network/284812.Q9P3U6High-affinity glucose transporter ght1; High-affinity glucose transporter.
ght8 protein networkhttps://string-db.org/network/284812.Q9P3U7Probable high-affinity hexose transporter ght8, mitochondrial.
dbl5 protein networkhttps://string-db.org/network/284812.Q9P3U8Uncharacterized RING finger protein C548.05c.
urm1 protein networkhttps://string-db.org/network/284812.Q9P3U9Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in [...]
wtf4 protein networkhttps://string-db.org/network/284812.Q9P3V0Uncharacterized protein wtf4.
SPBC1348.07 protein networkhttps://string-db.org/network/284812.Q9P3V3UPF0494 membrane protein C1348.07.
SPBC1348.05 protein networkhttps://string-db.org/network/284812.Q9P3V5Uncharacterized transporter C1348.05.
SPBC1348.04 protein networkhttps://string-db.org/network/284812.Q9P3V6Uncharacterized methyltransferase C1348.04; Probable methyltransferase.
ftm6 protein networkhttps://string-db.org/network/284812.Q9P3V7UPF0742 protein C1348.03.
tfa1 protein networkhttps://string-db.org/network/284812.Q9P3W1Transcription initiation factor IIE subunit alpha; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TF [...]
atg1803 protein networkhttps://string-db.org/network/284812.Q9P3W2SVP1-like protein 2; Involved in mitochondrial or peroxisomal functions and amino acid signaling pathways; Belongs to the WD repeat SVP1 family.
dli1 protein networkhttps://string-db.org/network/284812.Q9P3W4Dynein intermediate light chain dil1; Component of the cytoplasmic dynein which acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules (By similar [...]
tel2 protein networkhttps://string-db.org/network/284812.Q9P3W5DNA replication checkpoint protein tel2; Component of the TORC1 and TORC2 complexes required for the regulation of the cellular respons to changes in available nutrients. Required for normal entr [...]
SPAC458.02c protein networkhttps://string-db.org/network/284812.Q9P3W6Uncharacterized protein C458.02c.
cox8 protein networkhttps://string-db.org/network/284812.Q9P4W1Cytochrome c oxidase polypeptide VIII, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. [...]
apc5 protein networkhttps://string-db.org/network/284812.Q9P4W7Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through m [...]
rps403 protein networkhttps://string-db.org/network/284812.Q9P4W940S ribosomal protein S4-C; Belongs to the eukaryotic ribosomal protein eS4 family.
pdi4 protein networkhttps://string-db.org/network/284812.Q9P4X1Thioredoxin domain-containing protein C959.05c; Acts as a membrane-bound chaperone in endoplasmic reticulum quality control. Probably facilitates presentation of substrate to membrane-bound compo [...]
omh6 protein networkhttps://string-db.org/network/284812.Q9P4X2O-glycoside alpha-1,2-mannosyltransferase homolog 6; Probable mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins; Belongs to the glycosyltransferase 15 family.
utp7 protein networkhttps://string-db.org/network/284812.Q9P4X3Probable U3 small nucleolar RNA-associated protein 7; Involved in nucleolar processing of pre-18S ribosomal RNA.
sec17 protein networkhttps://string-db.org/network/284812.Q9P4X4Probable vesicular-fusion protein sec17 homolog; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus; Belongs to the SNAP family.
por1 protein networkhttps://string-db.org/network/284812.Q9P544Probable mitochondrial outer membrane protein porin; Forms a channel through the cell membrane that allows diffusion of small hydrophilic molecules.
rps002 protein networkhttps://string-db.org/network/284812.Q9P54640S ribosomal protein S0-B; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of th [...]
mug14 protein networkhttps://string-db.org/network/284812.Q9P5M9Meiotically up-regulated gene 14 protein; Has a role in meiosis.
abc3 protein networkhttps://string-db.org/network/284812.Q9P5N0ATP-binding cassette transporter abc3; Iron-regulated vacuolar ABC-type transporter which may be responsible for mobilizing stored iron from the vacuole to the cytosol in response to iron deficie [...]
pfl7 protein networkhttps://string-db.org/network/284812.Q9P5N1Putative cell-type specific agglutination protein pfl7; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexp [...]
aat1 protein networkhttps://string-db.org/network/284812.Q9P5N2Amino acid transporter 1; Probable amino acid transporter that may play a role in function in microtubule organization since it causes microtubule defects when overexpressed; Belongs to the amino [...]
alr2 protein networkhttps://string-db.org/network/284812.Q9P5N3Putative alanine racemase 2; Belongs to the alanine racemase family.
SPBC359.01 protein networkhttps://string-db.org/network/284812.Q9P5N4Uncharacterized amino-acid permease C359.01.
reb1 protein networkhttps://string-db.org/network/284812.Q9P6H9DNA-binding protein reb1; DNA-binding protein that recognizes sites within both the enhancer and the promoter of rRNA transcription, as well as upstream of many genes transcribed by RNA polymeras [...]
slm5 protein networkhttps://string-db.org/network/284812.Q9P6I0Asparagine--tRNA ligase, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family.
ubc16 protein networkhttps://string-db.org/network/284812.Q9P6I1Ubiquitin-conjugating enzyme E2 16; Catalyzes the covalent attachment of ubiquitin to other proteins.
dug1 protein networkhttps://string-db.org/network/284812.Q9P6I2Cys-Gly metallodipeptidase dug1; Catalytic component of the GSH degradosomal complex involved in the degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond. Has a Gly-C [...]
dfg502 protein networkhttps://string-db.org/network/284812.Q9P6I3Putative mannan endo-1,6-alpha-mannosidase C1198.07c; Belongs to the glycosyl hydrolase 76 family.
dfg501 protein networkhttps://string-db.org/network/284812.Q9P6I4Putative mannan endo-1,6-alpha-mannosidase C1198.06c.
guk1 protein networkhttps://string-db.org/network/284812.Q9P6I5Guanylate kinase; Essential for recycling GMP and indirectly, cGMP; Belongs to the guanylate kinase family.
SPBC1198.03c protein networkhttps://string-db.org/network/284812.Q9P6I6Uncharacterized protein C1198.03c.
dea2 protein networkhttps://string-db.org/network/284812.Q9P6I7Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. Also exhibits a low activity [...]
fmd2 protein networkhttps://string-db.org/network/284812.Q9P6I8Zinc-type alcohol dehydrogenase-like protein C1198.01; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
cha4 protein networkhttps://string-db.org/network/284812.Q9P6I9Uncharacterized transcriptional regulatory protein C1683.13c.
SPBC1683.12 protein networkhttps://string-db.org/network/284812.Q9P6J0Uncharacterized transporter C1683.12.
icl1 protein networkhttps://string-db.org/network/284812.Q9P6J1Mitochondrial 2-methylisocitrate lyase; Catalyzes the formation of pyruvate and succinate from 2- methylisocitrate during the metabolism of endogenous propionyl-CoA. Does not act on isocitrate (B [...]
pcl1 protein networkhttps://string-db.org/network/284812.Q9P6J2Fe(2+)/Mn(2+) transporter pcl1; Has a role in both calcium and manganese homeostasis. Involved in the transfer of iron and Mn(2+) from the cytosol to the vacuole for storage of these metals (By s [...]
mal1 protein networkhttps://string-db.org/network/284812.Q9P6J3Alpha-glucosidase; Belongs to the glycosyl hydrolase 13 family.
urh1 protein networkhttps://string-db.org/network/284812.Q9P6J4Uncharacterized protein C1683.06c.
SPBC1683.05 protein networkhttps://string-db.org/network/284812.Q9P6J5Uncharacterized permease C1683.05.
SPBC1683.04 protein networkhttps://string-db.org/network/284812.Q9P6J6Putative beta-glucosidase; Belongs to the glycosyl hydrolase 3 family.
SPBC1683.02 protein networkhttps://string-db.org/network/284812.Q9P6J8Uncharacterized deaminase C1683.02; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
pho841 protein networkhttps://string-db.org/network/284812.Q9P6J9Putative inorganic phosphate transporter C1683.01; High-affinity transporter for external inorganic phosphate. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
slr1 protein networkhttps://string-db.org/network/284812.Q9P6K0Uncharacterized HTH La-type RNA-binding protein C1527.03.
sft2 protein networkhttps://string-db.org/network/284812.Q9P6K1Protein transport protein sft2; Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex. Can be replaced by got1 (By similarit [...]
SPAC30C2.08 protein networkhttps://string-db.org/network/284812.Q9P6K3UPF0662 protein C30C2.08.
fnp1 protein networkhttps://string-db.org/network/284812.Q9P6K4Uncharacterized protein C30C2.07.
dml1 protein networkhttps://string-db.org/network/284812.Q9P6K5Protein dml1; Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance; Belongs to the misato family.
erv14 protein networkhttps://string-db.org/network/284812.Q9P6K6ER-derived vesicles protein erv14; Regulates export of the secretory proteins from the endoplasmic reticulum in COPII-coated vesicles. Belongs to the cornichon family.
asc1 protein networkhttps://string-db.org/network/284812.Q9P6K7tRNA-aminoacylation cofactor arc1; Binds to tRNA and functions as a cofactor for the methionyl- tRNA synthetase (MetRS) and glutamyl-tRNA synthetase (GluRS). Forms a complex with MetRS and GluRS [...]
mmd1 protein networkhttps://string-db.org/network/284812.Q9P6K9Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A [...]
set13 protein networkhttps://string-db.org/network/284812.Q9P6L2Ribosomal lysine N-methyltransferase 4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that monomethylates 60S ribosomal protein L42 (rpl42) at 'Lys-55'; Belongs to the cla [...]
end4 protein networkhttps://string-db.org/network/284812.Q9P6L5Endocytosis protein end4; Required for cellular morphogenesis and polarization of the cortical cytoskeleton. Required for establishment of new polarized growth zones where it acts in actin organi [...]
rev3 protein networkhttps://string-db.org/network/284812.Q9P6L6DNA polymerase zeta catalytic subunit; Nonessential DNA polymerase. Required for DNA damage induced mutagenesis. Involved in DNA repair, mitochondrial DNA repair and translesion synthesis. Has a [...]
rim2 protein networkhttps://string-db.org/network/284812.Q9P6L7Uncharacterized mitochondrial carrier C688.09.
srb8 protein networkhttps://string-db.org/network/284812.Q9P6L8Mediator of RNA polymerase II transcription subunit 12; Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation [...]
rng10 protein networkhttps://string-db.org/network/284812.Q9P6L9Uncharacterized protein C688.07c.
slx4 protein networkhttps://string-db.org/network/284812.Q9P6M0Structure-specific endonuclease subunit slx4; Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombinat [...]
gst3 protein networkhttps://string-db.org/network/284812.Q9P6M1Glutathione S-transferase 3; May have a role in the detoxification of various heavy metals.
SPAC688.03c protein networkhttps://string-db.org/network/284812.Q9P6M2Uncharacterized protein C688.03c.
mis14 protein networkhttps://string-db.org/network/284812.Q9P6M3Kinetochore protein mis14; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cyc [...]
SPAC652.01 protein networkhttps://string-db.org/network/284812.Q9P6M5Uncharacterized protein C652.01.
crp79 protein networkhttps://string-db.org/network/284812.Q9P6M8mRNA export factor crp79; Binds the poly(A) tail of mRNA. Involved in the export of mRNA from the nucleus to the cytoplasm.
mrpl1 protein networkhttps://string-db.org/network/284812.Q9P6M954S ribosomal protein L1, mitochondrial; Belongs to the universal ribosomal protein uL1 family.
atg1802 protein networkhttps://string-db.org/network/284812.Q9P6N1Autophagy-related protein 21; Required for cytoplasm to vacuole transport (Cvt) vesicles formation and autophagy (By similarity). Has a role in sporulation.
ptf1 protein networkhttps://string-db.org/network/284812.Q9P6N2Pdp3-interacting factor 1; Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3K14 ace [...]
she9 protein networkhttps://string-db.org/network/284812.Q9P6N3Sensitive to high expression protein 9 homolog, mitochondrial; Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes grow [...]
vps11 protein networkhttps://string-db.org/network/284812.Q9P6N4E3 ubiquitin-protein ligase pep5; Required for vacuolar biogenesis and for trafficking of hydrolase precursors to the vacuole. Mediates transport at the vacuolar membrane where it may be responsi [...]
sgp1 protein networkhttps://string-db.org/network/284812.Q9P6N5Dihydrosphingosine 1-phosphate phosphatase C823.11; Dihydrosphingosine 1-phosphate phosphatase required for efficient ceramide synthesis from exogenous sphingoid bases. Involved in endocytosis an [...]
hem25 protein networkhttps://string-db.org/network/284812.Q9P6N6Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step [...]
SPAC823.09c protein networkhttps://string-db.org/network/284812.Q9P6N7Putative threonine aspartase alpha chain.
rrp3 protein networkhttps://string-db.org/network/284812.Q9P6N8ATP-dependent rRNA helicase rrp3; ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
pga3 protein networkhttps://string-db.org/network/284812.Q9P6N9Protein PER1 homolog; Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anc [...]
taf3 protein networkhttps://string-db.org/network/284812.Q9P6P0Transcription initiation factor TFIID subunit 3; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA eleme [...]
tlg2 protein networkhttps://string-db.org/network/284812.Q9P6P1t-SNARE affecting a late Golgi compartment protein 2; t-SNARE that functions in transport from the endosome to the late Golgi and on the endocytic pathway; Belongs to the syntaxin family.
rrp36 protein networkhttps://string-db.org/network/284812.Q9P6P2rRNA biogenesis protein rrp36; Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway [...]
ppk15 protein networkhttps://string-db.org/network/284812.Q9P6P3Serine/threonine-protein kinase ppk15.
bet3 protein networkhttps://string-db.org/network/284812.Q9P6P5Transport protein particle subunit bet3.
mrpl9 protein networkhttps://string-db.org/network/284812.Q9P6P654S ribosomal protein L9, mitochondrial; Belongs to the universal ribosomal protein uL3 family.
rna15 protein networkhttps://string-db.org/network/284812.Q9P6P7Uncharacterized RNA-binding protein C644.16.
SPAC644.13c protein networkhttps://string-db.org/network/284812.Q9P6P8Protein YIP4; May be involved in proper membrane localization of Rab GTPases.
pkp1 protein networkhttps://string-db.org/network/284812.Q9P6P9[Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial; Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to th [...]
med11 protein networkhttps://string-db.org/network/284812.Q9P6Q0Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
SPAC644.09 protein networkhttps://string-db.org/network/284812.Q9P6Q1Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active f [...]
utr4 protein networkhttps://string-db.org/network/284812.Q9P6Q2Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1 [...]
bcs1 protein networkhttps://string-db.org/network/284812.Q9P6Q3Probable mitochondrial chaperone bcs1; Chaperone necessary for the assembly of mitochondrial respiratory chain complex III; Belongs to the AAA ATPase family. BCS1 subfamily.
dut1 protein networkhttps://string-db.org/network/284812.Q9P6Q5Probable deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases th [...]
pct1 protein networkhttps://string-db.org/network/284812.Q9P6Q6mRNA-capping enzyme subunit beta; First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end. Belongs to the fungal TPase family.
brf1 protein networkhttps://string-db.org/network/284812.Q9P6R0Transcription factor IIIB 60 kDa subunit; General activator of RNA polymerase III transcription.
vrp1 protein networkhttps://string-db.org/network/284812.Q9P6R1Verprolin; Involved in cytoskeletal organization and cellular growth. May exert its effects on the cytoskeleton directly, or indirectly via proline-binding proteins such as profilin or proteins p [...]
leo1 protein networkhttps://string-db.org/network/284812.Q9P6R2Uncharacterized protein C13E7.08c.
msd1 protein networkhttps://string-db.org/network/284812.Q9P6R4Meiotically up-regulated gene 172 protein; Has a role in meiosis; Belongs to the ADIP family.
gpi14 protein networkhttps://string-db.org/network/284812.Q9P6R5GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. [...]
atp16 protein networkhttps://string-db.org/network/284812.Q9P6R6ATP synthase subunit delta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane [...]
vts1 protein networkhttps://string-db.org/network/284812.Q9P6R7Protein vts1; RNA-binding protein involved in post-transcriptional regulation through transcript degradation. May be involved in vacuolar protein transport (By similarity).
cwf24 protein networkhttps://string-db.org/network/284812.Q9P6R8Pre-mRNA-splicing factor cwf24; Involved in mRNA splicing.
cwf22 protein networkhttps://string-db.org/network/284812.Q9P6R9Pre-mRNA-splicing factor cwf22; May be involved in pre-mRNA splicing.
gsf2 protein networkhttps://string-db.org/network/284812.Q9P6S0Galactose-specific cell agglutination protein gsf2; Galactose-specific adhesion protein essential for non-sexual flocculation and filamentous growth. Required for adhesion and filamentous growth [...]
SPBC27.05 protein networkhttps://string-db.org/network/284812.Q9P6S2Uncharacterized protein C27.05.
uds1 protein networkhttps://string-db.org/network/284812.Q9P6S3Up-regulated during septation protein 1; Involved in septation.
ask1 protein networkhttps://string-db.org/network/284812.Q9P6S5DASH complex subunit ask1; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates [...]
pga2 protein networkhttps://string-db.org/network/284812.Q9P6S6PGA2-homolog C27.01c; Involved processing and trafficking glycosylated proteins. Belongs to the PGA2 family.
per1 protein networkhttps://string-db.org/network/284812.Q9P768Uncharacterized amino-acid permease P7G5.06.
rpl1002 protein networkhttps://string-db.org/network/284812.Q9P76960S ribosomal protein L10-B.
prm1 protein networkhttps://string-db.org/network/284812.Q9P771Plasma membrane fusion protein prm1; Involved in cell fusion during mating by stabilizing the plasma membrane fusion event; Belongs to the PRM1 family.
gua2 protein networkhttps://string-db.org/network/284812.Q9P772GMP synthase [glutamine-hydrolyzing].
prp16 protein networkhttps://string-db.org/network/284812.Q9P774Pre-mRNA-splicing factor ATP-dependent RNA helicase prp16; Probable ATP-binding RNA helicase involved in pre-mRNA splicing.
pwp1 protein networkhttps://string-db.org/network/284812.Q9P775Uncharacterized WD repeat-containing protein C17D11.16.
SPBC1711.15c protein networkhttps://string-db.org/network/284812.Q9P776Uncharacterized protein C1711.15c.
his2 protein networkhttps://string-db.org/network/284812.Q9P777Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
ppp16 protein networkhttps://string-db.org/network/284812.Q9P778Dipeptidyl-peptidase 5.
atg2402 protein networkhttps://string-db.org/network/284812.Q9P779Sorting nexin C1711.11; Belongs to the sorting nexin family.
npl4 protein networkhttps://string-db.org/network/284812.Q9P780Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticu [...]
SPBC1711.09c protein networkhttps://string-db.org/network/284812.Q9P781Golgi apparatus membrane protein tvp38; Golgi membrane protein involved in vesicular trafficking and spindle migration.
aha1 protein networkhttps://string-db.org/network/284812.Q9P782Uncharacterized protein C1711.08; Belongs to the AHA1 family.
rrb1 protein networkhttps://string-db.org/network/284812.Q9P783Ribosome assembly protein rrb1; Involved in regulation of L3 expression and stability and plays a role in early 60S ribosomal subunit assembly. May be required for proper assembly of pre-ribosoma [...]
rpl401 protein networkhttps://string-db.org/network/284812.Q9P78460S ribosomal protein L4-B.
srp40 protein networkhttps://string-db.org/network/284812.Q9P785LisH domain-containing protein C1711.05.
mtd1 protein networkhttps://string-db.org/network/284812.Q9P786Methylenetetrahydrofolate dehydrogenase [NAD(+)]; Catalyzes oxidation of cytoplasmic one-carbon units for purine biosynthesis.
emc3 protein networkhttps://string-db.org/network/284812.Q9P787ER membrane protein complex subunit 3.
puf2 protein networkhttps://string-db.org/network/284812.Q9P789Pumilio domain-containing protein P35G2.14.
swc2 protein networkhttps://string-db.org/network/284812.Q9P790SWR complex protein 2; Participates in the catalytic exchange of histone H2A for the H2A variant pht1, an euchromatin-specific factor, leading to chromatin remodeling and changes in transcription [...]
ysa1 protein networkhttps://string-db.org/network/284812.Q9P791Uncharacterized Nudix hydrolase P35G2.12.
nbr1 protein networkhttps://string-db.org/network/284812.Q9P792ZZ-type zinc finger-containing protein P35G2.11c.
mit1 protein networkhttps://string-db.org/network/284812.Q9P793Chromatin remodeling factor mit1; Required for proper positioning of nucleosomes at heterochromatic loci and for transcriptional gene silencing (TGS) function of the Snf2/Hdac-containing represso [...]
usp103 protein networkhttps://string-db.org/network/284812.Q9P794U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. usp [...]
air1 protein networkhttps://string-db.org/network/284812.Q9P795Protein air1; Component of the TRAMP (TRF4) and TRAMP5 complexes which have a poly(A) RNA polymerase activity and are involved in a post- transcriptional quality control mechanism limiting inappr [...]
nup131 protein networkhttps://string-db.org/network/284812.Q9P797Nucleoporin nup131; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural component [...]
sgo1 protein networkhttps://string-db.org/network/284812.Q9P7A0Shugoshin-1; Plays a central role in chromosome cohesion during meiosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex disso [...]
txc1 protein networkhttps://string-db.org/network/284812.Q9P7A1PITH domain-containing protein P35G2.02.
stb3 protein networkhttps://string-db.org/network/284812.Q9P7B0Protein STB3 homolog.
rps802 protein networkhttps://string-db.org/network/284812.Q9P7B240S ribosomal protein S8-B.
sst1 protein networkhttps://string-db.org/network/284812.Q9P7B3Putative cation exchanger C521.04c; Putative cation exchanger; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
SPAC521.03 protein networkhttps://string-db.org/network/284812.Q9P7B4NADP-dependent 3-hydroxy acid dehydrogenase; NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP-dependent oxidation of L- allo-threonine t [...]
wss1 protein networkhttps://string-db.org/network/284812.Q9P7B5DNA-dependent metalloprotease WSS1 homolog; Metalloendopeptidase that acts selectively on DNA-binding proteins. DNA is needed to bring the protease and substrates together to enable proteolysis. [...]
ctr1 protein networkhttps://string-db.org/network/284812.Q9P7B7Uncharacterized protein C140.04.
arb1 protein networkhttps://string-db.org/network/284812.Q9P7B8Argonaute-binding protein 1; Component of the argonaute siRNA chaperone (ARC) complex which is required for histone H3K9 methylation, heterochromatin assembly and siRNA generation. The ARC comple [...]
rrp9 protein networkhttps://string-db.org/network/284812.Q9P7C0Uncharacterized WD repeat-containing protein C2E1P5.05.
erj5 protein networkhttps://string-db.org/network/284812.Q9P7C1Uncharacterized J domain-containing protein C2E1P5.03.
mns1 protein networkhttps://string-db.org/network/284812.Q9P7C3Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase; Involved in glycoprotein quality control as it is important for the targeting of misfolded glycoproteins for degradation. It [...]
cwf16 protein networkhttps://string-db.org/network/284812.Q9P7C5Splicing factor YJU2; Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the [...]
cwf23 protein networkhttps://string-db.org/network/284812.Q9P7C6Pre-mRNA-splicing factor cwf23; Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures [...]
prp11 protein networkhttps://string-db.org/network/284812.Q9P7C7Pre-mRNA-processing ATP-dependent RNA helicase prp11; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRN [...]
sld5 protein networkhttps://string-db.org/network/284812.Q9P7C8DNA replication complex GINS protein sld5; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation and is required for bir1 localizatio [...]
nhm1 protein networkhttps://string-db.org/network/284812.Q9P7C9m7GpppX diphosphatase; Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hyd [...]
SPBP4H10.19c protein networkhttps://string-db.org/network/284812.Q9P7D0Uncharacterized protein P4H10.19c.
SPBP4H10.18c protein networkhttps://string-db.org/network/284812.Q9P7D1Uncharacterized protein P4H10.18c.
SPBP4H10.17c protein networkhttps://string-db.org/network/284812.Q9P7D2Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. Demethylates the phosphatase PP2A catalytic subunit (By similarity); Belongs to the AB hyd [...]
SPBP4H10.16c protein networkhttps://string-db.org/network/284812.Q9P7D3WHI2-like protein P4H10.16c.
aco2 protein networkhttps://string-db.org/network/284812.Q9P7D4Homocitrate dehydratase, mitochondrial; Catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
SPBP4H10.12 protein networkhttps://string-db.org/network/284812.Q9P7D6UPF0303 protein P4H10.12; Belongs to the UPF0303 family.
lcf2 protein networkhttps://string-db.org/network/284812.Q9P7D7Long-chain-fatty-acid--CoA ligase 2; Esterification, concomitant with transport, of endogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorp [...]
rbd3 protein networkhttps://string-db.org/network/284812.Q9P7D8Uncharacterized rhomboid protein P4H10.10, mitochondrial.
rsv1 protein networkhttps://string-db.org/network/284812.Q9P7D9Zinc finger protein rsv1; Involved in maintaining cell viability under glucose starvation conditions. May have a role in regulating genes involved in gluconeogenesis.
qcr10 protein networkhttps://string-db.org/network/284812.Q9P7E0Cytochrome b-c1 complex subunit 10; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which d [...]
SPBP4H10.07 protein networkhttps://string-db.org/network/284812.Q9P7E1Uncharacterized RING finger protein P4H10.07.
spe2 protein networkhttps://string-db.org/network/284812.Q9P7E3S-adenosylmethionine decarboxylase alpha chain; Belongs to the eukaryotic AdoMetDC family.
adg1 protein networkhttps://string-db.org/network/284812.Q9P7E7Protein adg1.
abp1 protein networkhttps://string-db.org/network/284812.Q9P7E8Protein app1.
dpp1 protein networkhttps://string-db.org/network/284812.Q9P7E9Putative dipeptidyl aminopeptidase C14C4.15c.
cbm1 protein networkhttps://string-db.org/network/284812.Q9P7F1Carbohydrate-binding domain-containing protein C2E1P3.05c.
cao1 protein networkhttps://string-db.org/network/284812.Q9P7F2Copper amine oxidase 1; Copper amine oxidase involved in the metabolism of xenobiotic and biogenic amines. Capable of catalyzing the oxidative deamination of primary amines such as ethylamine as [...]
amt3 protein networkhttps://string-db.org/network/284812.Q9P7F3Ammonium transporter 3; Transporter for ammonium to use as a nitrogen source. Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
SPAC2E1P3.01 protein networkhttps://string-db.org/network/284812.Q9P7F4Zinc-type alcohol dehydrogenase-like protein C2E1P3.01.
vps32 protein networkhttps://string-db.org/network/284812.Q9P7F7Vacuolar-sorting protein snf7; Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB).
get3 protein networkhttps://string-db.org/network/284812.Q9P7F8ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA prot [...]
ctr5 protein networkhttps://string-db.org/network/284812.Q9P7F9Copper transport protein ctr5; Required for high affinity copper (probably reduced Cu I) transport into the cell.
noc201 protein networkhttps://string-db.org/network/284812.Q9P7G0Uncharacterized NOC2 family protein C1142.04.
SPAP14E8.05c protein networkhttps://string-db.org/network/284812.Q9P7G3TMEM14 protein homolog P14E8.05c.
oma1 protein networkhttps://string-db.org/network/284812.Q9P7G4Mitochondrial metalloendopeptidase OMA1; Protease that is part of the quality control system in the inner membrane of mitochondria. Cleaves and thereby promotes the turnover of mistranslated or m [...]
bos1 protein networkhttps://string-db.org/network/284812.Q9P7G5Protein transport protein bos1; SNARE required for targeting and fusion of ER-derived transport vesicles with the Golgi complex.
tos4 protein networkhttps://string-db.org/network/284812.Q9P7G6Transcription factor P14E8.02; Probable transcriptional regulatory protein Required for G1/S progression.
SPAC1782.12c protein networkhttps://string-db.org/network/284812.Q9P7G8UPF0382 membrane protein C1782.12c.
met14 protein networkhttps://string-db.org/network/284812.Q9P7G9Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. Required for methionine synthesis.
nhp2 protein networkhttps://string-db.org/network/284812.Q9P7H0H/ACA ribonucleoprotein complex subunit nhp2; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for [...]
clp1 protein networkhttps://string-db.org/network/284812.Q9P7H1Tyrosine-protein phosphatase CDC14 homolog; Protein phosphatase which antagonizes mitotic cyclin- dependent kinase cdc2, the inactivation of which is essential for exit from mitosis. To access it [...]
rex3 protein networkhttps://string-db.org/network/284812.Q9P7H2RNA exonuclease 3; 3' to 5' exoribonuclease required for proper 3' end maturation of MRP RNA and of the U5L snRNA; Belongs to the REXO1/REXO3 family.
phb1 protein networkhttps://string-db.org/network/284812.Q9P7H3Prohibitin-1; Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins. Has an antiproliferative activity. Regulates replicative life span [...]
ypa2 protein networkhttps://string-db.org/network/284812.Q9P7H4Serine/threonine-protein phosphatase 2A activator 2; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as [...]
cox24 protein networkhttps://string-db.org/network/284812.Q9P7H5Mitochondrial mRNA-processing protein cox24; May be involved in the splicing of the mitochondrial mRNA. Belongs to the mitochondrion-specific ribosomal protein mS38 family.
saf3 protein networkhttps://string-db.org/network/284812.Q9P7H6Uncharacterized protein C1782.03.
ecm29 protein networkhttps://string-db.org/network/284812.Q9P7H8Proteasome component ecm29; Stabilizes the proteasome holoenzyme, probably by tethering the 20S proteolytic core particle and the 19S regulatory particle. The proteasome is a multicatalytic prote [...]
SPAC105.02c protein networkhttps://string-db.org/network/284812.Q9P7I0Ankyrin repeat-containing protein C105.02c.
kha1 protein networkhttps://string-db.org/network/284812.Q9P7I1K(+)/H(+) antiporter 1; Potassium-proton antiport; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
cmk1 protein networkhttps://string-db.org/network/284812.Q9P7I2Calcium/calmodulin-dependent protein kinase type I; Important in cell cycle regulation; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
mdv1 protein networkhttps://string-db.org/network/284812.Q9P7I3Mitochondrial division protein 1; Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promo [...]
nts1 protein networkhttps://string-db.org/network/284812.Q9P7I7Uncharacterized protein C24B10.19c.
SPCC24B10.18 protein networkhttps://string-db.org/network/284812.Q9P7I8UPF0390 protein C24B10.18; Belongs to the UPF0390 family.
emp24 protein networkhttps://string-db.org/network/284812.Q9P7I9Endosomal protein P24B; Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi (By similarit [...]
swt1 protein networkhttps://string-db.org/network/284812.Q9P7J1Transcriptional protein swt1; Involved in transcription; Belongs to the SWT1 family.
xlf1 protein networkhttps://string-db.org/network/284812.Q9P7J2Xrcc4-like factor 1; Involved in non-homologous end joining (NHEJ) in the repair of double-strand DNA breaks (DSB). Has a role in meiosis. Belongs to the XLF family.
cgi121 protein networkhttps://string-db.org/network/284812.Q9P7J3EKC/KEOPS complex subunit cgi121; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codon [...]
tho7 protein networkhttps://string-db.org/network/284812.Q9P7J4THO complex subunit mft1; Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export. The THO complex is recruited to transcribed genes a [...]
yta4 protein networkhttps://string-db.org/network/284812.Q9P7J5Uncharacterized AAA domain-containing protein C24B10.10c.
rps1702 protein networkhttps://string-db.org/network/284812.Q9P7J640S ribosomal protein S17-B.
ada2 protein networkhttps://string-db.org/network/284812.Q9P7J7Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcri [...]
gad8 protein networkhttps://string-db.org/network/284812.Q9P7J8Serine/threonine-protein kinase gad8; Involved in a signaling module for sexual development and cell growth under stressed conditions. Required for G1 arrest under nitrogen starvation and for gro [...]
tim9 protein networkhttps://string-db.org/network/284812.Q9P7K0Mitochondrial import inner membrane translocase subunit tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mit [...]
SPCC24B10.02c protein networkhttps://string-db.org/network/284812.Q9P7K3Uncharacterized kinase C24B10.02c.
git1 protein networkhttps://string-db.org/network/284812.Q9P7K5Adenylate cyclase activation protein git1; Involved in the glucose/cAMP-signaling pathway. Required for maintaining basal cAMP levels and for producing a glucose-triggered cAMP response.
rtc3 protein networkhttps://string-db.org/network/284812.Q9P7K6SDO1-like protein C21C3.19; May play a role in RNA metabolism; Belongs to the SDO1-like family.
spt4 protein networkhttps://string-db.org/network/284812.Q9P7K8Transcription elongation factor spt4; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be [...]
SPBC21C3.15c protein networkhttps://string-db.org/network/284812.Q9P7K9Putative aldehyde dehydrogenase-like protein C21C3.
SPBC21C3.12c protein networkhttps://string-db.org/network/284812.Q9P7L1Thioredoxin domain-containing protein C21C3.12c.
rib7 protein networkhttps://string-db.org/network/284812.Q9P7L32,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase; Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6- [...]
oaa1 protein networkhttps://string-db.org/network/284812.Q9P7L4Uncharacterized hydrolase C21C3.09c.
car2 protein networkhttps://string-db.org/network/284812.Q9P7L5Ornithine aminotransferase car2.
trm140 protein networkhttps://string-db.org/network/284812.Q9P7L6Uncharacterized methyltransferase-like protein SPBC21C3.07c; Probable S-adenosyl-L-methionine-dependent methyltransferase that mediates 3-methylcytidine modification of some tRNAs.
sap62 protein networkhttps://string-db.org/network/284812.Q9P7L8Pre-mRNA-splicing factor sap62; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
mrx14 protein networkhttps://string-db.org/network/284812.Q9P7L9Probable 54S ribosomal protein L34, mitochondrial.
SPBC21C3.03 protein networkhttps://string-db.org/network/284812.Q9P7M0ABC1 family protein C21C3.03, mitochondrial.
dep1 protein networkhttps://string-db.org/network/284812.Q9P7M1Transcriptional regulatory protein dep1; Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histo [...]
slx1 protein networkhttps://string-db.org/network/284812.Q9P7M3Structure-specific endonuclease subunit slx1; Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombinati [...]
nop10 protein networkhttps://string-db.org/network/284812.Q9P7M5H/ACA ribonucleoprotein complex subunit nop10; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for [...]
nup184 protein networkhttps://string-db.org/network/284812.Q9P7M8Nucleoporin nup184; Interacts with pom152 in the core structure of the nuclear pore complex (NPC). Involved in the export of mRNA.
rib1 protein networkhttps://string-db.org/network/284812.Q9P7M9Probable GTP cyclohydrolase-2.
meu32 protein networkhttps://string-db.org/network/284812.Q9P7N0Meiotically up-regulated gene 11 protein; Has a role in meiosis.
bud32 protein networkhttps://string-db.org/network/284812.Q9P7N1EKC/KEOPS complex subunit SPAP27G11.07c; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that rea [...]
vas2 protein networkhttps://string-db.org/network/284812.Q9P7N2AP-1 complex subunit sigma-1; Component of the AP-1 complex which links clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasm [...]
vps41 protein networkhttps://string-db.org/network/284812.Q9P7N3Vacuolar protein sorting-associated protein 41; Required for vacuolar assembly and vacuolar traffic.
tad3 protein networkhttps://string-db.org/network/284812.Q9P7N4tRNA-specific adenosine deaminase subunit tad3; Deaminates adenosine-34 to inosine in many tRNAs.
cdc123 protein networkhttps://string-db.org/network/284812.Q9P7N5Cell division cycle protein 123; Regulates the cell cycle in a nutrient dependent manner.
mgr3 protein networkhttps://string-db.org/network/284812.Q9P7N6TPR repeat-containing protein P27G11.02.
trs31 protein networkhttps://string-db.org/network/284812.Q9P7N9Transport protein particle subunit trs31; TRAPP plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.
sct1 protein networkhttps://string-db.org/network/284812.Q9P7P0Uncharacterized acyltransferase C1718.04.
ker1 protein networkhttps://string-db.org/network/284812.Q9P7P1DNA-directed RNA polymerase I subunit rpa14; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
hop1 protein networkhttps://string-db.org/network/284812.Q9P7P2Meiosis-specific protein hop1; Constituent of the linear elements (LE) during meiosis, the S.pombe equivalents of synaptonemal complexes.
pdc102 protein networkhttps://string-db.org/network/284812.Q9P7P6Probable pyruvate decarboxylase C186.09; Belongs to the TPP enzyme family.
SPAC186.08c protein networkhttps://string-db.org/network/284812.Q9P7P7Probable L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. LDH family.
SPAC186.07c protein networkhttps://string-db.org/network/284812.Q9P7P82-hydroxyacid dehydrogenase homolog 1.
SPAC186.06 protein networkhttps://string-db.org/network/284812.Q9P7P9Uncharacterized isomerase C186.06; Belongs to the PhzF family.
gdt1 protein networkhttps://string-db.org/network/284812.Q9P7Q0GDT1-like protein C186.05c.
SPAC186.02c protein networkhttps://string-db.org/network/284812.Q9P7Q12-hydroxyacid dehydrogenase homolog 2.
pfl9 protein networkhttps://string-db.org/network/284812.Q9P7Q2Putative cell agglutination protein pfl9; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed.
sec18 protein networkhttps://string-db.org/network/284812.Q9P7Q4Vesicular-fusion protein sec18; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic [...]
SPAC1834.10c protein networkhttps://string-db.org/network/284812.Q9P7Q5Uncharacterized protein C1834.10c.
mak1 protein networkhttps://string-db.org/network/284812.Q9P7Q7Peroxide stress-activated histidine kinase mak1; Involved in the control of the SAPK-dependent transcriptional response to peroxide stress. Also has a role in G2/M regulation.
pmo25 protein networkhttps://string-db.org/network/284812.Q9P7Q8Mo25-like protein; Belongs to the Mo25 family.
alg9 protein networkhttps://string-db.org/network/284812.Q9P7Q9Alpha-1,2-mannosyltransferase alg9; Catalyzes the transfer of mannose from Dol-P-Man to lipid- linked oligosaccharides.
aro1 protein networkhttps://string-db.org/network/284812.Q9P7R03-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; be [...]
mtr3 protein networkhttps://string-db.org/network/284812.Q9P7R3Exosome complex component mtr3; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrada [...]
ubc8 protein networkhttps://string-db.org/network/284812.Q9P7R4Ubiquitin-conjugating enzyme E2 8; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family.
gfh1 protein networkhttps://string-db.org/network/284812.Q9P7R5Gamma-tubulin complex component gfh1; Required for proper anchoring of astral microtubules at the spindle pole bodies (SPBs), during anaphase, ensuring correct cell polarity; Belongs to the TUBGC [...]
sap10 protein networkhttps://string-db.org/network/284812.Q9P7R6Uncharacterized protein C211.05; Belongs to the SF3B5 family.
gea1 protein networkhttps://string-db.org/network/284812.Q9P7R8Uncharacterized protein C211.03.
cwf3 protein networkhttps://string-db.org/network/284812.Q9P7R9Pre-mRNA-splicing factor cwf3; Involved in pre-mRNA splicing and cell cycle progression. Belongs to the crooked-neck family.
htr12 protein networkhttps://string-db.org/network/284812.Q9P7S1PDZ domain-containing protein C23G3.12c; Belongs to the peptidase S1C family.
rpn6 protein networkhttps://string-db.org/network/284812.Q9P7S2Probable 26S proteasome regulatory subunit rpn6; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. [...]
ssr3 protein networkhttps://string-db.org/network/284812.Q9P7S3SWI/SNF and RSC complexes subunit ssr3; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particula [...]
taf4 protein networkhttps://string-db.org/network/284812.Q9P7S4Transcription initiation factor TFIID subunit 4; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA eleme [...]
ubp7 protein networkhttps://string-db.org/network/284812.Q9P7S5Probable ubiquitin carboxyl-terminal hydrolase 7.
snf30 protein networkhttps://string-db.org/network/284812.Q9P7S6SWI/SNF chromatin-remodeling complex subunit snf30; Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expr [...]
nop58 protein networkhttps://string-db.org/network/284812.Q9P7S7Nucleolar protein 58; Required for pre-18S rRNA processing. May bind microtubules (By similarity); Belongs to the NOP5/NOP56 family.
SPAC23G3.05c protein networkhttps://string-db.org/network/284812.Q9P7S8Protein rax1; May be involved in cell polarization and division.
ies4 protein networkhttps://string-db.org/network/284812.Q9P7S9INO80 complex subunit 4; Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
sib2 protein networkhttps://string-db.org/network/284812.Q9P7T0L-ornithine N(5)-monooxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as ferrichro [...]
sib1 protein networkhttps://string-db.org/network/284812.Q9P7T1Hydroxamate-type ferrichrome siderophore peptide synthetase; Involved in intracellular and extracellular ferrichrome siderophore biosynthesis; Belongs to the ATP-dependent AMP-binding enzyme fami [...]
mrc1 protein networkhttps://string-db.org/network/284812.Q9P7T4Mediator of replication checkpoint protein 1; Component of the replisome and is required for rad3-dependent activation of the checkpoint kinase cds1 in response to replication fork arrest. Phosph [...]
SPAC694.04c protein networkhttps://string-db.org/network/284812.Q9P7T6UPF0160 protein C694.04c; Belongs to the UPF0160 (MYG1) family.
SPAC694.03 protein networkhttps://string-db.org/network/284812.Q9P7T7Putative nicotinamide mononucleotide adenylyltransferase; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Involved in the salvage pathway for NAD(+) biosynthesis [...]
SPAC694.02 protein networkhttps://string-db.org/network/284812.Q9P7T8Uncharacterized helicase C694.02.
SPAC977.17 protein networkhttps://string-db.org/network/284812.Q9P7T9Uncharacterized membrane protein C977.17; Belongs to the MIP/aquaporin (TC 1.A.8) family.
SPAC977.15 protein networkhttps://string-db.org/network/284812.Q9P7U1Uncharacterized AIM2 family protein C977.15.
SPAC977.14c protein networkhttps://string-db.org/network/284812.Q9P7U2Putative aryl-alcohol dehydrogenase C977.14c.
SPAC977.06 protein networkhttps://string-db.org/network/284812.Q9P7U3UPF0494 membrane protein C977.06.
SPAC977.05c protein networkhttps://string-db.org/network/284812.Q9P7U4VEL1-related protein AC977.05c; Belongs to the VEL1 family.
abc4 protein networkhttps://string-db.org/network/284812.Q9P7V2ATP-binding cassette transporter abc4; Involved in detoxification of xenobiotics, and vacuolar sequestration of glutathione S-conjugates. Together with abc2, required for accumulation of a red pi [...]
tsn1 protein networkhttps://string-db.org/network/284812.Q9P7V3Translin-1; DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations. Selectively binds single-stranded d(GT)n and d(GTT)n mi [...]
kti12 protein networkhttps://string-db.org/network/284812.Q9P7V4Protein kti12; Elongator-associated factor that is not a structural subunit but rather transiently contacts Elongator, presumably to promote its interaction with elongation competent pol II. Requ [...]
sec72 protein networkhttps://string-db.org/network/284812.Q9P7V5Protein transport protein sec72; May play a role in protein transport.
vps33 protein networkhttps://string-db.org/network/284812.Q9P7V6Vacuolar protein sorting-associated protein 33; Essential for vacuolar biogenesis, maturation and function. Involved in the sorting of vacuolar proteins from the Golgi apparatus and their targeti [...]
SPBC1703.13c protein networkhttps://string-db.org/network/284812.Q9P7V8Probable mitochondrial phosphate carrier protein; Transport of phosphate groups from the cytosol to the mitochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family.
ubp9 protein networkhttps://string-db.org/network/284812.Q9P7V9Probable ubiquitin carboxyl-terminal hydrolase 9; Ubiquitin C-terminal hydrolase involved in regulating actin dynamics and/or endocytosis at cell tips and septa. Belongs to the peptidase C19 fami [...]
opa3 protein networkhttps://string-db.org/network/284812.Q9P7W0OPA3-like protein; Belongs to the OPA3 family.
fau1 protein networkhttps://string-db.org/network/284812.Q9P7W2Probable 5-formyltetrahydrofolate cyclo-ligase.
acl1 protein networkhttps://string-db.org/network/284812.Q9P7W3Probable ATP-citrate synthase subunit 1; Catalyzes the formation of cytosolic acetyl-CoA, which is mainly used for the biosynthesis of fatty acids and sterols. Belongs to the succinate/malate CoA [...]
pof10 protein networkhttps://string-db.org/network/284812.Q9P7W4F-box/WD repeat-containing protein pof10; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
rio2 protein networkhttps://string-db.org/network/284812.Q9P7W5Serine/threonine-protein kinase rio2; Required for the final endonucleolytic cleavage of 20S pre- rRNA at site D in the cytoplasm, converting it into the mature 18S rRNA. Involved in normal expor [...]
mlh1 protein networkhttps://string-db.org/network/284812.Q9P7W6Putative MutL protein homolog 1; This protein is involved in the repair of mismatches in DNA.
syo2 protein networkhttps://string-db.org/network/284812.Q9P7W7Uncharacterized ARM-like repeat-containing protein C1703.03c.
rsc9 protein networkhttps://string-db.org/network/284812.Q9P7W8Chromatin structure-remodeling complex subunit rsc9; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Contr [...]
pop4 protein networkhttps://string-db.org/network/284812.Q9P7W9Probable ribonuclease P protein subunit 1; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
tim18 protein networkhttps://string-db.org/network/284812.Q9P7X0Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial ele [...]
qcr1 protein networkhttps://string-db.org/network/284812.Q9P7X1Probable mitochondrial-processing peptidase subunit beta; Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported p [...]
ell1 protein networkhttps://string-db.org/network/284812.Q9P7X2RNA polymerase II elongation factor ell1; Activates transcription elongation by RNA polymerase II and pyrophosphorolysis as a complex with eaf1. Elongation factor that can increase the catalytic [...]
frg1 protein networkhttps://string-db.org/network/284812.Q9P7X3Protein frg1; May have a role in processing of pre-rRNA or in the assembly of rRNA into ribosomal subunits. May be involved in pre-mRNA splicing (By similarity).
SPBP23A10.11c protein networkhttps://string-db.org/network/284812.Q9P7X4Uncharacterized serine-rich protein P23A10.11c.
ppk32 protein networkhttps://string-db.org/network/284812.Q9P7X5Protein kinase domain-containing protein ppk32.
psf1 protein networkhttps://string-db.org/network/284812.Q9P7X6DNA replication complex GINS protein psf1; The GINS complex plays an essential role in the initiation of DNA replication.
alp5 protein networkhttps://string-db.org/network/284812.Q9P7X7Actin-related protein 4; Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation [...]
rpa2 protein networkhttps://string-db.org/network/284812.Q9P7X8Probable DNA-directed RNA polymerase I subunit RPA2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second lar [...]
mtm1 protein networkhttps://string-db.org/network/284812.Q9P7X9Uncharacterized mitochondrial carrier P23A10.06.
ssr4 protein networkhttps://string-db.org/network/284812.Q9P7Y0SWI/SNF and RSC complexes subunit ssr4; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particula [...]
sdh7 protein networkhttps://string-db.org/network/284812.Q9P7Y2Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) [...]
pkr1 protein networkhttps://string-db.org/network/284812.Q9P7Y3V-type ATPase assembly factor pkr1; Functions together with the other V-type ATPase assembly factors in the endoplasmic reticulum to efficiently assemble the V-type ATPase membrane sector V(0); B [...]
med14 protein networkhttps://string-db.org/network/284812.Q9P7Y4Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
pro3 protein networkhttps://string-db.org/network/284812.Q9P7Y7Pyrroline-5-carboxylate reductase.
mid2 protein networkhttps://string-db.org/network/284812.Q9P7Y8Septin ring organizing protein mid2; Responsible for the proper stability and function of septins during cytokinesis. Required for the correct formation of the medial septin ring structure in mit [...]
sin1 protein networkhttps://string-db.org/network/284812.Q9P7Y9Target of rapamycin complex 2 subunit sin1; Component of TORC2, which regulates multiple cellular processes to control cell growth in response to environmental signals. TORC2 is required for cell [...]
efm4 protein networkhttps://string-db.org/network/284812.Q9P7Z3Protein-lysine N-methyltransferase efm4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role [...]
SPBC2A9.13 protein networkhttps://string-db.org/network/284812.Q9P7Z4Uncharacterized protein C2A9.13.
SPCC5E4.10c protein networkhttps://string-db.org/network/284812.Q9P7Z6Uncharacterized protein C5E4.10c.
cox17 protein networkhttps://string-db.org/network/284812.Q9P7Z7Cytochrome c oxidase copper chaperone; Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity). Belongs to the COX17 famil [...]
SPBC26H8.13c protein networkhttps://string-db.org/network/284812.Q9P7Z8Uncharacterized protein C26H8.13c.
hap2 protein networkhttps://string-db.org/network/284812.Q9P7Z9Uncharacterized protein C16C4.20c.
SPCC777.17c protein networkhttps://string-db.org/network/284812.Q9P801Probable 54S ribosomal protein L9, mitochondrial.
mis18 protein networkhttps://string-db.org/network/284812.Q9P802Kinetochore protein mis18; Component of the CENP-A recruiting complex that ensures the integrity of mitotic spindles through maintenance of kinetochore factors mis6/CENP-I and cnp1/CENP-A. Mainta [...]
trm1 protein networkhttps://string-db.org/network/284812.Q9P804tRNA (guanine(26)-N(2))-dimethyltransferase; Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
dcp1 protein networkhttps://string-db.org/network/284812.Q9P805mRNA-decapping enzyme subunit 1; Component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense- mediated mRNA decay. Removes the 7-methyl [...]
erg10 protein networkhttps://string-db.org/network/284812.Q9UQW6Acetyl-CoA acetyltransferase; Catalyzes the formation of acetoacetyl-CoA in the biosynthesis of mevalonate, an intermediate required for the biosynthesis of sterols and nonsterol isoprenoids; Bel [...]
spe1 protein networkhttps://string-db.org/network/284812.Q9UQW9Ornithine decarboxylase; Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and sp [...]
sod2 protein networkhttps://string-db.org/network/284812.Q9UQX0Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese [...]
pam1 protein networkhttps://string-db.org/network/284812.Q9UQY2Probable proteasome subunit beta type-6; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent t [...]
spo4 protein networkhttps://string-db.org/network/284812.Q9UQY9Cell cycle protein kinase spo4; Required for the initiation of meiosis II and progression through anaphase II.
dlc2 protein networkhttps://string-db.org/network/284812.Q9UR05Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to a [...]
mmf2 protein networkhttps://string-db.org/network/284812.Q9UR06Protein mmf2, mitochondrial; Plays a role in the maintenance of mitochondrial DNA. Belongs to the RutC family.
Tf2-11 protein networkhttps://string-db.org/network/284812.Q9UR07Transposon Tf2-11 polyprotein.
psu1 protein networkhttps://string-db.org/network/284812.Q9UR09Probable secreted beta-glucosidase PSU1; Involved in cell wall synthesis. May be required for the activation of 1,3-beta-glucan synthase; Belongs to the SUN family.
nrf1 protein networkhttps://string-db.org/network/284812.Q9UR17Vacuolar transporter chaperone 1; Component of the vacuolar transporter chaperone (VTC) complex, which plays a role in vacuolar membrane fusion (By similarity). Involved in the control of cell po [...]
rhp26 protein networkhttps://string-db.org/network/284812.Q9UR24DNA repair protein rhp26; Involved in transcription-coupled repair (TCR).
mrpl31 protein networkhttps://string-db.org/network/284812.Q9UR2754S ribosomal protein L31, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL60 family.
hst4 protein networkhttps://string-db.org/network/284812.Q9UR39NAD-dependent protein deacetylase hst4; NAD-dependent histone deacetylase, which contributes to both telomeric and centromeric silencing, proper cell cycle progression, DNA damage control, recomb [...]
tkt1 protein networkhttps://string-db.org/network/284812.Q9URM2Probable transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
tho1 protein networkhttps://string-db.org/network/284812.Q9URT2Uncharacterized protein P25A2.03.
ams2 protein networkhttps://string-db.org/network/284812.Q9URT4CENP-A multicopy suppressor protein 2; Required for proper chromosome segregation via regulation of CENP-A localization to the centromere.
rpl3402 protein networkhttps://string-db.org/network/284812.Q9URT860S ribosomal protein L34-B.
gsk31 protein networkhttps://string-db.org/network/284812.Q9URT9Protein kinase gsk31; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
dna2 protein networkhttps://string-db.org/network/284812.Q9URU2DNA replication ATP-dependent helicase/nuclease dna2; Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape fen1: flap [...]
pfl5 protein networkhttps://string-db.org/network/284812.Q9URU4Putative cell agglutination protein pfl5; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed ; Belon [...]
exg1 protein networkhttps://string-db.org/network/284812.Q9URU6Glucan 1,3-beta-glucosidase 1; Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. It could also function biosynthetically as a transglyc [...]
gid9 protein networkhttps://string-db.org/network/284812.Q9URU9Protein fyv10; Involved in the proteasome-dependent degradation of fructose- 1,6-bisphosphatase; Belongs to the FYV10 family.
tho4 protein networkhttps://string-db.org/network/284812.Q9URV0Uncharacterized RNA-binding protein C106.12c.
plg7 protein networkhttps://string-db.org/network/284812.Q9URV1Putative phospholipase A2; Belongs to the serine esterase family.
cut4 protein networkhttps://string-db.org/network/284812.Q9URV2Anaphase-promoting complex subunit 1; Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through m [...]
mug2 protein networkhttps://string-db.org/network/284812.Q9URV3Meiotically up-regulated gene 2 protein; Has a role in meiosis; Belongs to the UPF0612 family.
nat2 protein networkhttps://string-db.org/network/284812.Q9URV4Uncharacterized protein C106.07c; To A.thaliana At2g20940.
tim11 protein networkhttps://string-db.org/network/284812.Q9URV6ATP synthase subunit e, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
SPBC106.03 protein networkhttps://string-db.org/network/284812.Q9URV8UPF0744 protein C106.03.
srx1 protein networkhttps://string-db.org/network/284812.Q9URV9Sulfiredoxin; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step proces [...]
SPAPJ695.01c protein networkhttps://string-db.org/network/284812.Q9URW1UPF0321 protein PJ695.01c; Belongs to the UPF0321 family.
SPAPJ691.02 protein networkhttps://string-db.org/network/284812.Q9URW3Protein yippee-like PJ691.02; Belongs to the yippee family.
lsb4 protein networkhttps://string-db.org/network/284812.Q9URW6SH3 domain-containing protein PJ696.02; Belongs to the SH3YL1 family.
vps17 protein networkhttps://string-db.org/network/284812.Q9URW7Vacuolar protein sorting-associated protein 17; Plays a role in vesicular protein sorting. Required for the endosome-to-Golgi retrieval of the vacuolar protein sorting receptor pep1/vps10. Compon [...]
atd2 protein networkhttps://string-db.org/network/284812.Q9URW9Putative aldehyde dehydrogenase-like protein C922.07c.
SPAC922.06 protein networkhttps://string-db.org/network/284812.Q9URX0Uncharacterized oxidoreductase C922.06.
SPAC922.04 protein networkhttps://string-db.org/network/284812.Q9URX2Uncharacterized protein C922.04.
SPAC922.03 protein networkhttps://string-db.org/network/284812.Q9URX3Probable 1-aminocyclopropane-1-carboxylate deaminase; Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-k [...]
gto1 protein networkhttps://string-db.org/network/284812.Q9URX4Uncharacterized family 31 glucosidase C1039.11c.
rpl31 protein networkhttps://string-db.org/network/284812.Q9URX660S ribosomal protein L31; Belongs to the eukaryotic ribosomal protein eL31 family.
rmt1 protein networkhttps://string-db.org/network/284812.Q9URX7Protein arginine N-methyltransferase 1; S-adenosyl-L-methionine-dependent protein-arginine N- methyltransferase that catalyzes both the mono- and asymmetric (type I) dimethylation of the guanidin [...]
nup155 protein networkhttps://string-db.org/network/284812.Q9URX8Probable nucleoporin C890.06.
pxr1 protein networkhttps://string-db.org/network/284812.Q9URX9Protein pxr1; Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase; Belongs to the PINX1 family.
ytm1 protein networkhttps://string-db.org/network/284812.Q9URY0Ribosome biogenesis protein ytm1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
ppk16 protein networkhttps://string-db.org/network/284812.Q9URY1Serine/threonine-protein kinase ppk16; Has a role in meiosis; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
alp7 protein networkhttps://string-db.org/network/284812.Q9URY2Microtubule protein alp7; Required for bipolar spindle formation and proper chromosome segregation. Has an indirect role in connecting the kinetochores and the plus end of pole to chromosome micr [...]
tbc13 protein networkhttps://string-db.org/network/284812.Q9URY3TBC domain-containing protein C1952.17c; May act as a GTPase-activating protein for Rab family protein(s).
SPAC869.01 protein networkhttps://string-db.org/network/284812.Q9URY4Putative amidase C869.01; Belongs to the amidase family.
yhb1 protein networkhttps://string-db.org/network/284812.Q9URY5Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects th [...]
SPAC869.03c protein networkhttps://string-db.org/network/284812.Q9URY6Probable urea active transporter 3; Involved in active transport of urea; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
SPAC869.04 protein networkhttps://string-db.org/network/284812.Q9URY7Putative formamidase C869.04; Hydrolyzes formamide with the production of ammonia which can be used as a source of nitrogen for growth. May also act on acetamide, propanamide and butanamide (By s [...]
sul2 protein networkhttps://string-db.org/network/284812.Q9URY8Probable sulfate permease C869.05c; High affinity uptake of sulfate into the cell; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
hry1 protein networkhttps://string-db.org/network/284812.Q9URY9Uncharacterized hemerythrin-like protein C869.06c.
mel1 protein networkhttps://string-db.org/network/284812.Q9URZ0Alpha-galactosidase mel1; Secreted alpha-galactosidase required for catabolic conversion of melibiose to glucose and galactose.
pcm2 protein networkhttps://string-db.org/network/284812.Q9URZ1Probable protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L- [...]
SPAC869.09 protein networkhttps://string-db.org/network/284812.Q9URZ2UPF0654 protein C869.09.
put4 protein networkhttps://string-db.org/network/284812.Q9URZ3Probable proline-specific permease put4; Required for high-affinity proline transport. May be responsible for proline recognition and probably also for proline translocation across the plasma mem [...]
cat1 protein networkhttps://string-db.org/network/284812.Q9URZ4Cationic amino acid transporter 1; Major permease specifically involved in arginine and lysine uptake.
vps1 protein networkhttps://string-db.org/network/284812.Q9URZ5Vacuolar protein sorting-associated protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
SPAC732.02c protein networkhttps://string-db.org/network/284812.Q9URZ7Probable fructose-2,6-bisphosphatase C732.02c; This is predominantly if not solely a fructose-2,6- bisphosphatase; In the C-terminal section; belongs to the phosphoglycerate mutase family.
vma11 protein networkhttps://string-db.org/network/284812.Q9URZ8V-type proton ATPase 16 kDa proteolipid subunit 2; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety [...]
amt2 protein networkhttps://string-db.org/network/284812.Q9US00Ammonium transporter 2; Transporter for ammonium to use as a nitrogen source. Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
sdh6 protein networkhttps://string-db.org/network/284812.Q9US02Succinate dehydrogenase assembly factor 1, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) [...]
klp2 protein networkhttps://string-db.org/network/284812.Q9US03Kinesin-like protein 2; Microtubule-dependent motor that is involved in microtubule organization in the mitotic spindle. Required for the polarization of interphase microtubules where it orients [...]
ggt1 protein networkhttps://string-db.org/network/284812.Q9US04Glutathione hydrolase 1 heavy chain; Catalyzes the transfer of the gamma-glutamyl moiety of glutathione (GSH) and other gamma-glutamyl compounds to amino acids and peptides. Major GSH-degrading e [...]
bfr2 protein networkhttps://string-db.org/network/284812.Q9US05Protein bfr2.
paf1 protein networkhttps://string-db.org/network/284812.Q9US06RNA polymerase II-associated protein 1 homolog.
arp8 protein networkhttps://string-db.org/network/284812.Q9US07Probable actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Exhibits low basal ATPase activity, and [...]
spo3 protein networkhttps://string-db.org/network/284812.Q9US08Sporulation-specific protein 3; Has a role in spore morphogenesis. Involved in the assembly of the forespore membrane.
btn1 protein networkhttps://string-db.org/network/284812.Q9US09Protein btn1; Involved in vacuolar transport and vacuole pH homeostasis. Also required for cytokinesis; Belongs to the battenin family.
mil1 protein networkhttps://string-db.org/network/284812.Q9US10Uncharacterized membrane protein C6F6.13c.
SPAC607.06c protein networkhttps://string-db.org/network/284812.Q9US12Putative zinc metalloproteinase C607.06c.
rpn9 protein networkhttps://string-db.org/network/284812.Q9US13Probable 26S proteasome regulatory subunit rpn9; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
arg82 protein networkhttps://string-db.org/network/284812.Q9US14Uncharacterized inositol polyphosphate kinase C607.04.
SPAC607.02c protein networkhttps://string-db.org/network/284812.Q9US15UPF0653 protein C607.02c.
slc1 protein networkhttps://string-db.org/network/284812.Q9US20Uncharacterized acyltransferase C1851.02.
rpl1502 protein networkhttps://string-db.org/network/284812.Q9US2260S ribosomal protein L15-B.
atg12 protein networkhttps://string-db.org/network/284812.Q9US24Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with atg5 through a ub [...]
hrp1 protein networkhttps://string-db.org/network/284812.Q9US25Chromodomain helicase hrp1; Seems to play a role in mitotic chromosome segregation and maintenance of chromatin structure. Has ATPase activity.
fta2 protein networkhttps://string-db.org/network/284812.Q9US26Inner kinetochore subunit fta2; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segre [...]
vps66 protein networkhttps://string-db.org/network/284812.Q9US27Putative lysophosphatidic acid:oleoyl-CoA acyltransferase; Acyl-CoA-dependent lysophosphatidic acid acyltransferase with preference for oleoyl-CoA. Involved in triacylglyceride homeostasis and li [...]
SPAC1783.01 protein networkhttps://string-db.org/network/284812.Q9US28Uncharacterized FAD-binding protein C1783.01; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
rsm19 protein networkhttps://string-db.org/network/284812.Q9US30Probable ribosomal protein S19, mitochondrial.
SPAC1039.08 protein networkhttps://string-db.org/network/284812.Q9US33Putative serine acetyltransferase.
SPAC1039.07c protein networkhttps://string-db.org/network/284812.Q9US34Uncharacterized aminotransferase C1039.07c.
SPAC1039.06 protein networkhttps://string-db.org/network/284812.Q9US35D-serine dehydratase; Converts specifically D-serine to pyruvate and ammonia. May play a role in D-serine detoxification (By similarity); Belongs to the DSD1 family.
klf1 protein networkhttps://string-db.org/network/284812.Q9US36Zinc finger protein klf1; Required for maintaining cell viability in nitrogen-deficient stationary phase (G0) cells.
SPAC1039.04 protein networkhttps://string-db.org/network/284812.Q9US37Uncharacterized transporter C1039.04.
SPAC1039.03 protein networkhttps://string-db.org/network/284812.Q9US38AB hydrolase superfamily protein C1039.03.
SPAC1039.02 protein networkhttps://string-db.org/network/284812.Q9US39Uncharacterized protein C1039.02.
SPAC1039.01 protein networkhttps://string-db.org/network/284812.Q9US40Uncharacterized amino-acid permease C1039.01.
urg1 protein networkhttps://string-db.org/network/284812.Q9US41Uracil-regulated protein 1; Belongs to the GTP cyclohydrolase II family.
urg3 protein networkhttps://string-db.org/network/284812.Q9US42Protein urg3; Belongs to the URC4/urg3 family.
urg2 protein networkhttps://string-db.org/network/284812.Q9US43Putative uracil phosphoribosyltransferase urg2; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate; Belongs to the UPRTase family.
tna1 protein networkhttps://string-db.org/network/284812.Q9US44Uncharacterized transporter C1002.16c.
med6 protein networkhttps://string-db.org/network/284812.Q9US45Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Me [...]
itt1 protein networkhttps://string-db.org/network/284812.Q9US46E3 ubiquitin-protein ligase itt1.
SPAC1002.12c protein networkhttps://string-db.org/network/284812.Q9US47Putative succinate-semialdehyde dehydrogenase C1002.12c [NADP(+)]; Belongs to the aldehyde dehydrogenase family.
gaa1 protein networkhttps://string-db.org/network/284812.Q9US48GPI transamidase component gaa1; Component of the GPI transamidase complex. Required for a terminal step of GPI anchor attachment onto proteins (By similarity).
sgt1 protein networkhttps://string-db.org/network/284812.Q9US49Protein ecdysoneless homolog; Involved in the regulation of carbohydrate metabolism. May act as a transcription factor; Belongs to the ECD family.
mtf1 protein networkhttps://string-db.org/network/284812.Q9US51Mitochondrial transcription factor 1; Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with [...]
bqt2 protein networkhttps://string-db.org/network/284812.Q9US52Telomere bouquet protein 2; Involved in chromosome segregation. During meiotic prophase, connects telomeres to the spindle pole body by forming a bridge between the telomere protein rap1 and the [...]
jmj2 protein networkhttps://string-db.org/network/284812.Q9US53Jumonji/ARID domain-containing protein 2.
taf11 protein networkhttps://string-db.org/network/284812.Q9US54Transcription initiation factor TFIID subunit 11; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA elem [...]
gls2 protein networkhttps://string-db.org/network/284812.Q9US55Glucosidase 2 subunit alpha; Catalytic subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precur [...]
pom34 protein networkhttps://string-db.org/network/284812.Q9US56Meiotically up-regulated gene 31 protein; Has a role in meiosis.
skb5 protein networkhttps://string-db.org/network/284812.Q9US59Shk1 kinase-binding protein 5; Stimulates catalytic function of the p21-activated kinase homolog shk1.
klp3 protein networkhttps://string-db.org/network/284812.Q9US60Kinesin-like protein 3; Cytoplasmic motor that could play a role in Golgi membrane recycling; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
alg12 protein networkhttps://string-db.org/network/284812.Q9USD4Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7) [...]
rpl35A01 protein networkhttps://string-db.org/network/284812.Q9USG660S ribosomal protein L33-B.
tcb2 protein networkhttps://string-db.org/network/284812.Q9USG8Meiotically up-regulated gene 190 protein; Has a role in meiosis.
tdp1 protein networkhttps://string-db.org/network/284812.Q9USG9Probable tyrosyl-DNA phosphodiesterase; DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' [...]
med31 protein networkhttps://string-db.org/network/284812.Q9USH1Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
SPCP31B10.02 protein networkhttps://string-db.org/network/284812.Q9USH2UPF0651 protein P31B10.02, mitochondrial.
pwi1 protein networkhttps://string-db.org/network/284812.Q9USH5PWI domain-containing protein C825.05c.
naa40 protein networkhttps://string-db.org/network/284812.Q9USH6N-alpha-acetyltransferase 40; N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A. Belongs to the acetyltransferase family. NAA4 [...]
psy1 protein networkhttps://string-db.org/network/284812.Q9USH7Syntaxin-like protein psy1.
gbs1 protein networkhttps://string-db.org/network/284812.Q9USH8Glucosidase 2 subunit beta; Subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of imma [...]
SPCC825.01 protein networkhttps://string-db.org/network/284812.Q9USH9Uncharacterized ABC transporter ATP-binding protein C825.01.
SPCC794.15 protein networkhttps://string-db.org/network/284812.Q9USI0Uncharacterized protein C794.15.
sac32 protein networkhttps://string-db.org/network/284812.Q9USI4SAC3 family protein 2.
sti1 protein networkhttps://string-db.org/network/284812.Q9USI5Heat shock protein sti1 homolog; May play a role in mediating the heat shock response of some HSP70 genes.
myo2 protein networkhttps://string-db.org/network/284812.Q9USI6Myosin type-2 heavy chain 1; Required for cell division. It is a component of the cdc12 'spot', a structure thought to mark the site of septation. May work in conjunction with myo3; Belongs to th [...]
tum1 protein networkhttps://string-db.org/network/284812.Q9USJ1Probable 3-mercaptopyruvate sulfurtransferase; Required for formation of the 2-thio group of the 5- methoxycarbonylmethyl-2-thiouridine modified base in some tRNAs.
got1 protein networkhttps://string-db.org/network/284812.Q9USJ2Protein transport protein got1; Nonessential protein required for the fusion of ER-derived transport vesicles with the Golgi complex. Can be replaced by sft2 (By similarity); Belongs to the GOT1 [...]
mam301 protein networkhttps://string-db.org/network/284812.Q9USJ3Uncharacterized protein C4B3.03c.
nte1 protein networkhttps://string-db.org/network/284812.Q9USJ4Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lip [...]
hem12 protein networkhttps://string-db.org/network/284812.Q9USJ5Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
SPCC4B3.06c protein networkhttps://string-db.org/network/284812.Q9USJ6NAD(P)H-dependent FMN reductase C4B3.06c; Has several reductase activities that are NAD(P)H-dependent and involve FMN as a cofactor. May be involved in ferric iron assimilation (By similarity).
nro1 protein networkhttps://string-db.org/network/284812.Q9USJ7Negative regulator of ofd1; Required for correct translation termination (By similarity). Positive regulator of the stability of the N-terminal transcription factor domain (Sre1N) of sre1 which i [...]
lsg1 protein networkhttps://string-db.org/network/284812.Q9USJ8CTD kinase subunit gamma; Subunit of the CTDK-I complex, which hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit. As part of the CTDK-I [...]
mrpl12 protein networkhttps://string-db.org/network/284812.Q9USJ954S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family.
ipk1 protein networkhttps://string-db.org/network/284812.Q9USK0Inositol-pentakisphosphate 2-kinase; Has kinase activity and phosphorylates inositol-1,3,4,5,6- pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6- hexakisphosphate (InsP6), also known a [...]
fra3 protein networkhttps://string-db.org/network/284812.Q9USK1Uncharacterized bolA-like protein C4B3.11c.
set9 protein networkhttps://string-db.org/network/284812.Q9USK2Histone-lysine N-methyltransferase set9; Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4 to form H4K20me3. H4 'Lys-20' methylation is apparently not involved in t [...]
SPCC4B3.13 protein networkhttps://string-db.org/network/284812.Q9USK3Uncharacterized transporter C4B3.13.
cwf20 protein networkhttps://string-db.org/network/284812.Q9USK4Pre-mRNA-splicing factor cwf20; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
tip41 protein networkhttps://string-db.org/network/284812.Q9USK5Type 2A phosphatase activator tip41; Involved in negative regulation of the TOR signaling pathway in response to type of available nitrogen source. Activates the PP2A phosphatase ppa2; Belongs to [...]
cbp3 protein networkhttps://string-db.org/network/284812.Q9USK6CBP3-like protein; Belongs to the CBP3 family.
ppc1 protein networkhttps://string-db.org/network/284812.Q9USK7Uncharacterized protein C4B3.18.
ags1 protein networkhttps://string-db.org/network/284812.Q9USK8Cell wall alpha-1,3-glucan synthase ags1; Required for alpha-1,3-glucan and alpha-1,4-glucan production which are required for cell wall synthesis.
tho3 protein networkhttps://string-db.org/network/284812.Q9USL1Uncharacterized WD repeat-containing protein C18B5.10c.
SPCC18B5.09c protein networkhttps://string-db.org/network/284812.Q9USL2Uncharacterized protein C18B5.09c.
ism1 protein networkhttps://string-db.org/network/284812.Q9USL3Isoleucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
nup61 protein networkhttps://string-db.org/network/284812.Q9USL4Nucleoporin nup61; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components [...]
dom34 protein networkhttps://string-db.org/network/284812.Q9USL5Protein dom34; Involved in protein translation. Together with hbs1, may function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- [...]
SPCC18B5.05c protein networkhttps://string-db.org/network/284812.Q9USL6Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase C18B5.05c; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. Belongs to th [...]
rsm18 protein networkhttps://string-db.org/network/284812.Q9USL737S ribosomal protein rsm18, mitochondrial; Belongs to the bacterial ribosomal protein bS18 family.
rpn1302 protein networkhttps://string-db.org/network/284812.Q9USM1Probable proteasomal ubiquitin receptor ADRM1 homolog; May function as a proteasomal ubiquitin receptor. May promote the deubiquitinating activity associated with the 26S proteasome (By similarit [...]
SPCC16A11.15c protein networkhttps://string-db.org/network/284812.Q9USM2Uncharacterized protein C16A11.15c.
sfh1 protein networkhttps://string-db.org/network/284812.Q9USM3Chromatin structure-remodeling complex subunit sfh1; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Contr [...]
luc7 protein networkhttps://string-db.org/network/284812.Q9USM4U1 snRNP-associated protein usp106; Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the splice [...]
ubp1 protein networkhttps://string-db.org/network/284812.Q9USM5Probable ubiquitin carboxyl-terminal hydrolase 1.
oca8 protein networkhttps://string-db.org/network/284812.Q9USM6Probable cytochrome b5 2; Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases; Belongs to the cytochrome b5 family.
tim23 protein networkhttps://string-db.org/network/284812.Q9USM7Mitochondrial import inner membrane translocase subunit tim23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across th [...]
atg20 protein networkhttps://string-db.org/network/284812.Q9USM8Autophagy-related protein 20; Required for cytoplasm to vacuole transport (Cvt), pexophagy and mitophagy. Also involved in endoplasmic reticulum-specific autophagic process and is essential for t [...]
coq10 protein networkhttps://string-db.org/network/284812.Q9USM9Coenzyme Q-binding protein coq10, mitochondrial; Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site [...]
gpi10 protein networkhttps://string-db.org/network/284812.Q9USN0GPI mannosyltransferase 3; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By si [...]
snx12 protein networkhttps://string-db.org/network/284812.Q9USN1Sorting nexin-12.
utp13 protein networkhttps://string-db.org/network/284812.Q9USN3Probable U3 small nucleolar RNA-associated protein 13; Involved in nucleolar processing of pre-18S ribosomal RNA.
gdh2 protein networkhttps://string-db.org/network/284812.Q9USN5Probable NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate; Belongs to the Glu/Leu/Phe/Val dehydrogenases [...]
hst2 protein networkhttps://string-db.org/network/284812.Q9USN7NAD-dependent protein deacetylase hst2; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin fam [...]
rqc2 protein networkhttps://string-db.org/network/284812.Q9USN8Ribosome quality control complex subunit 2; Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synt [...]
gcn3 protein networkhttps://string-db.org/network/284812.Q9USP0Translation initiation factor eIF-2B subunit alpha; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP.
elp4 protein networkhttps://string-db.org/network/284812.Q9USP1Elongator complex protein 4; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in trans [...]
ynd1 protein networkhttps://string-db.org/network/284812.Q9USP2Golgi apyrase; Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates. Required for Golgi glycosylation and cell wall integrity. Involved in N-mannosylation of pr [...]
ppr6 protein networkhttps://string-db.org/network/284812.Q9USP3Pentatricopeptide repeat-containing protein 6, mitochondrial; Mitochondrial RNA-binding protein required for the stability of the atp9 mRNA.
jnm1 protein networkhttps://string-db.org/network/284812.Q9USP4Meiotically up-regulated gene 1 protein; Required for correct meiotic chromosome segregation.
gpi8 protein networkhttps://string-db.org/network/284812.Q9USP5GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidatio [...]
clc1 protein networkhttps://string-db.org/network/284812.Q9USP6Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
mto2 protein networkhttps://string-db.org/network/284812.Q9USP7Uncharacterized protein C902.06.
idh2 protein networkhttps://string-db.org/network/284812.Q9USP8Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle and is involved in glutamate biosynthesis. Also binds RNA; s [...]
rmn1 protein networkhttps://string-db.org/network/284812.Q9USP9Uncharacterized RNA-binding protein C902.04.
nem2 protein networkhttps://string-db.org/network/284812.Q9USQ0Sporulation-specific protein spo7; Probable regulatory component of the nem1-spo7 complex which acts as a phosphatase and may be required for proper nuclear membrane morphology.
ctf18 protein networkhttps://string-db.org/network/284812.Q9USQ1Chromosome transmission fidelity protein 18; Essential for the fidelity of chromosome transmission. Required for the DNA replication block checkpoint. Replication factor C (RFC) complex has an es [...]
alp6 protein networkhttps://string-db.org/network/284812.Q9USQ2Spindle pole body component alp6; Component of the gamma tubule complex that is required for the regulation of both interphase microtubules and mitotic bipolar spindles; Belongs to the TUBGCP fam [...]
sim3 protein networkhttps://string-db.org/network/284812.Q9USQ4NASP-related protein sim3; Histone H3 and H3-like CENP-A-specific chaperone. Promotes delivery and incorporation of CENP-A in centromeric chromatin, probably by escorting nascent CENP-A to CENP-A [...]
spa1 protein networkhttps://string-db.org/network/284812.Q9USQ5Ornithine decarboxylase antizyme; Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracell [...]
syj2 protein networkhttps://string-db.org/network/284812.Q9USQ6Inositol-1,4,5-trisphosphate 5-phosphatase 2; Controls the cellular levels and subcellular distribution of phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5- bisphosphate. Involved in [...]
dph6 protein networkhttps://string-db.org/network/284812.Q9USQ7Diphthine--ammonia ligase; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP. Diphthamide biosynthesis consists in the conversion of an L-histidine residue i [...]
SPBC577.11 protein networkhttps://string-db.org/network/284812.Q9USQ8Uncharacterized protein C577.11.
pre4 protein networkhttps://string-db.org/network/284812.Q9USQ9Probable proteasome subunit beta type-7; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent t [...]
ckn1 protein networkhttps://string-db.org/network/284812.Q9USR0DNA excision repair protein ckn1; Adapter protein for ddb1/cullin 4 ubiquitin ligases involved in transcription-coupled nucleotide excision repair.
txl1 protein networkhttps://string-db.org/network/284812.Q9USR1Thioredoxin-like protein 1; Has a role in cellular detoxification of alkyl hydroperoxide.
ubp10 protein networkhttps://string-db.org/network/284812.Q9USR2Probable mRNA-splicing protein ubp10; May play a role in mRNA splicing. It is unsure if the protein really exhibits hydrolase activity. Could be a competitor of ubiquitin C-terminal hydrolases (U [...]
stt4 protein networkhttps://string-db.org/network/284812.Q9USR3Phosphatidylinositol 4-kinase stt4; Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,- trisphosphate.
rec27 protein networkhttps://string-db.org/network/284812.Q9USR4Meiotic recombination protein rec27; Required for correct meiotic chromosome segregation and recombination.
tho5 protein networkhttps://string-db.org/network/284812.Q9USR5Uncharacterized THOC5 family protein.
SPBC577.03c protein networkhttps://string-db.org/network/284812.Q9USR6N-acetyltransferase 9-like protein.
rpl3801 protein networkhttps://string-db.org/network/284812.Q9USR760S ribosomal protein L38-1.
cnp3 protein networkhttps://string-db.org/network/284812.Q9USR9Inner kinetochore subunit cnp3; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segre [...]
pnc1 protein networkhttps://string-db.org/network/284812.Q9USS0Nicotinamidase; Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway; Belongs to the isochorismatase family.
SPBC557.05 protein networkhttps://string-db.org/network/284812.Q9USS1Uncharacterized protein C557.05; Belongs to the arrestin family.
ppk29 protein networkhttps://string-db.org/network/284812.Q9USS2Serine/threonine-protein kinase ppk29.
SPBC557.02c protein networkhttps://string-db.org/network/284812.Q9USS4Uncharacterized protein C557.02c.
SPBC4.06 protein networkhttps://string-db.org/network/284812.Q9USS6Probable acid phosphatase SPBC4.06; Belongs to the histidine acid phosphatase family.
sfb3 protein networkhttps://string-db.org/network/284812.Q9USS7Uncharacterized protein C4.03c; Belongs to the SEC23/SEC24 family. SEC24 subfamily.
SPBC4.02c protein networkhttps://string-db.org/network/284812.Q9USS8Uncharacterized protein C4.02c.
dni2 protein networkhttps://string-db.org/network/284812.Q9USS9Delayed minus-nitrogen induction protein 2; Belongs to the SUR7 family.
ppk26 protein networkhttps://string-db.org/network/284812.Q9UST1PAN2-PAN3 deadenylation complex subunit pan3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN speci [...]
mmp2 protein networkhttps://string-db.org/network/284812.Q9UST2Mitochondrial inner membrane protease subunit 2; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into th [...]
vps52 protein networkhttps://string-db.org/network/284812.Q9UST3Vacuolar protein sorting-associated protein 52; Involved in retrograde transport from early and late endosomes to late Golgi by linking the vesicle through the t-SNARE TGL1 to the Golgi, leading [...]
tif512 protein networkhttps://string-db.org/network/284812.Q9UST4Eukaryotic translation initiation factor 5A-2; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of deca [...]
rrn7 protein networkhttps://string-db.org/network/284812.Q9UST5RNA polymerase I-specific transcription initiation factor rrn7; Component of RNA polymerase I core factor complex (CF) that acts as a sua7/TFIIB-like factor and plays a key role in multiple steps [...]
spc24 protein networkhttps://string-db.org/network/284812.Q9UST6Kinetochore protein spc24; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cyc [...]
sfc3 protein networkhttps://string-db.org/network/284812.Q9UST7Transcription factor tau subunit sfc3; TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the i [...]
rnh1 protein networkhttps://string-db.org/network/284812.Q9UST8Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
hen1 protein networkhttps://string-db.org/network/284812.Q9UST9Small RNA 2'-O-methyltransferase; Methyltransferase that adds a 2'-O-methyl group at the 3'-end of small RNAs; Belongs to the methyltransferase superfamily. HEN1 family.
efc25 protein networkhttps://string-db.org/network/284812.Q9USU1Ras guanine nucleotide exchange factor efc25; Has a role in chromosome segregation and cell morphology upstream of the ras1-scd1 pathway. Promotes the exchange of ras1-bound GDP by GTP leading to [...]
cdh1 protein networkhttps://string-db.org/network/284812.Q9USU2Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle; Belongs to the class I-like SA [...]
fbh1 protein networkhttps://string-db.org/network/284812.Q9USU3F-box DNA helicase protein 1; Involved in ATP-dependent DNA-unwinding in a 3' to 5' direction, and ATP-ase activities stimulated by the single-stranded DNA-binding protein ssb1. Essential for via [...]
gas2 protein networkhttps://string-db.org/network/284812.Q9USU51,3-beta-glucanosyltransferase gas2; Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan mol [...]
hmo1 protein networkhttps://string-db.org/network/284812.Q9USU7HMG box-containing protein C28F2.11.
ngg1 protein networkhttps://string-db.org/network/284812.Q9USU8Chromatin-remodeling complexes subunit ngg1; Transcription regulator. Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA, SLIK and ADA. SAGA is [...]
toa1 protein networkhttps://string-db.org/network/284812.Q9USU9Transcription initiation factor IIA large subunit; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a c [...]
hrd3 protein networkhttps://string-db.org/network/284812.Q9USV0Putative ERAD-associated E3 ubiquitin-protein ligase component; Component of the endoplasmic reticulum quality control (ERQC) system involved in ubiquitin-dependent degradation of missfolded endo [...]
sfr1 protein networkhttps://string-db.org/network/284812.Q9USV1Swi5-dependent recombination DNA repair protein 1; Involved in DNA recombination repair and meiotic chromosome segregation; Belongs to the SFR1/MEI5 family.
SPBC28F2.05c protein networkhttps://string-db.org/network/284812.Q9USV2Uncharacterized oxidoreductase C28F2.05.
cwf7 protein networkhttps://string-db.org/network/284812.Q9USV3Pre-mRNA-splicing factor cwf7; Involved in mRNA splicing; Belongs to the SPF27 family.
mep33 protein networkhttps://string-db.org/network/284812.Q9USV4mRNA export protein 33; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural compo [...]
cbp4 protein networkhttps://string-db.org/network/284812.Q9USV6Assembly factor cbp4; Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (B [...]
ctr6 protein networkhttps://string-db.org/network/284812.Q9USV7Copper transport protein ctr6; Mobilizes stored copper from the vacuole to the cytoplasm under conditions of copper limitation; Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A [...]
ath1 protein networkhttps://string-db.org/network/284812.Q9USW1Uncharacterized protein C21B10.03c.
inp2 protein networkhttps://string-db.org/network/284812.Q9USW2Inheritance of peroxisomes protein 2; Required for peroxisome inheritance. Acts as the peroxisome- specific receptor for the myosin V motor myo2 (By similarity). Belongs to the INP2 family.
crr1 protein networkhttps://string-db.org/network/284812.Q9USW3Probable glycosidase C21B10.07.
SPBC21B10.09 protein networkhttps://string-db.org/network/284812.Q9USW4Uncharacterized protein C21B10.09.
rps402 protein networkhttps://string-db.org/network/284812.Q9USW540S ribosomal protein S4-B; Belongs to the eukaryotic ribosomal protein eS4 family.
dpm2 protein networkhttps://string-db.org/network/284812.Q9USW6Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Essential for the ER localization and stable expression of dpm1 (By similarit [...]
mni1 protein networkhttps://string-db.org/network/284812.Q9USW8Uncharacterized protein C19C7.01.
sgf29 protein networkhttps://string-db.org/network/284812.Q9USW9SAGA-associated factor 29; Chromatin reader component of the transcription regulatory histone acetylation (HAT) complex SAGA. Sgf29 specifically recognizes and binds methylated 'Lys-4' of histone [...]
pvg3 protein networkhttps://string-db.org/network/284812.Q9USX0Beta-1,3-galactosyltransferase pvg3; Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moeities to galactomannans and their subsequent pyruvylation. Has a role in meiosi [...]
ape2 protein networkhttps://string-db.org/network/284812.Q9USX1Aminopeptidase 1.
rad60 protein networkhttps://string-db.org/network/284812.Q9USX3DNA repair protein rad60; Required for repair of DNA double strand breaks which occur during replication, or induced by UV or gamma radiation, via recombination between sister chromatids. This ha [...]
rpl35A02 protein networkhttps://string-db.org/network/284812.Q9USX460S ribosomal protein L33-A.
ppk22 protein networkhttps://string-db.org/network/284812.Q9USX7Serine/threonine-protein kinase ppk22.
lea1 protein networkhttps://string-db.org/network/284812.Q9USX8U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity).
elc1 protein networkhttps://string-db.org/network/284812.Q9USX9Elongin-C; Prevents degradation of interacting proteins by the proteasome.
mug131 protein networkhttps://string-db.org/network/284812.Q9USY0Meiotically up-regulated gene 131 protein; Has a role in meiosis; Belongs to the UPF0300 family.
SPBC1861.05 protein networkhttps://string-db.org/network/284812.Q9USY1Pseudouridine-metabolizing bifunctional protein C1861.05; Bifunctional enzyme that catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP), and the reversible cleavag [...]
prp24 protein networkhttps://string-db.org/network/284812.Q9USY2Uncharacterized RNA-binding protein C1861.04c.
naa35 protein networkhttps://string-db.org/network/284812.Q9USY3N-alpha-acetyltransferase 35, NatC auxiliary subunit; Component of the NatC N-terminal acetyltransferase. Belongs to the MAK10 family.
abp2 protein networkhttps://string-db.org/network/284812.Q9USY4ARS-binding protein 2; Binds, preferentially, to the Maundrell ARS consensus sequence within ARS3002.
fzo1 protein networkhttps://string-db.org/network/284812.Q9USY7Transmembrane GTPase fzo1; Probable transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondrial [...]
gem8 protein networkhttps://string-db.org/network/284812.Q9USY8Uncharacterized protein C16H5.15.
trm734 protein networkhttps://string-db.org/network/284812.Q9USZ0Uncharacterized WD repeat-containing protein C1306.02; May play a role in the regulation of the retromer complex and in the recycling from endosomes of plasma membrane proteins. May be involved i [...]
mef1 protein networkhttps://string-db.org/network/284812.Q9USZ1Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from t [...]
mtr10 protein networkhttps://string-db.org/network/284812.Q9USZ2Uncharacterized protein C11G11.07.
sme1 protein networkhttps://string-db.org/network/284812.Q9USZ3Small nuclear ribonucleoprotein E; Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the S [...]
rpa34 protein networkhttps://string-db.org/network/284812.Q9USZ4DNA-directed RNA polymerase I subunit rpa34; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
trs20 protein networkhttps://string-db.org/network/284812.Q9USZ5Transport protein particle 20 kDa subunit; Component of the TRAPP I and TRAPP II complexes. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II seems t [...]
mrt4 protein networkhttps://string-db.org/network/284812.Q9USZ6Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, [...]
end3 protein networkhttps://string-db.org/network/284812.Q9USZ7Actin cytoskeleton-regulatory complex protein end3; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The [...]
fis1 protein networkhttps://string-db.org/network/284812.Q9USZ8Mitochondrial fission 1 protein; Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation (By similarity).
tcb3 protein networkhttps://string-db.org/network/284812.Q9UT00Uncharacterized protein PYUK71.03c.
sec71 protein networkhttps://string-db.org/network/284812.Q9UT02Protein transport protein sec71; May play a role in protein transport.
sls1 protein networkhttps://string-db.org/network/284812.Q9UT03Protein sls1; Involved in aerobic respiration where it is required for assembly of respiratory chain enzyme complexes III and IV. Also has a role in mitochondrial gene expression (By similarity); [...]
gid10 protein networkhttps://string-db.org/network/284812.Q9UT04Uncharacterized protein P8A3.13c.
tpp2 protein networkhttps://string-db.org/network/284812.Q9UT05Tripeptidyl-peptidase 2 homolog.
mtg2 protein networkhttps://string-db.org/network/284812.Q9UT06Uncharacterized GTP-binding protein P8A3.11c, mitochondrial.
ups1 protein networkhttps://string-db.org/network/284812.Q9UT07Protein ups1 homolog; Required for maintenance of normal mitochondrial morphology as well as PCP1-dependent processing of MGM1.
paa1 protein networkhttps://string-db.org/network/284812.Q9UT08Protein phosphatase PP2A regulatory subunit A; Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellular morphogenesis, and p [...]
SPAP8A3.07c protein networkhttps://string-db.org/network/284812.Q9UT09Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptu [...]
ski7 protein networkhttps://string-db.org/network/284812.Q9UT10Uncharacterized GTP-binding protein P8A3.05.
zip3 protein networkhttps://string-db.org/network/284812.Q9UT11Uncharacterized zinc transporter P8A3.03.
ofd2 protein networkhttps://string-db.org/network/284812.Q9UT12Uncharacterized protein P8A3.02c.
atp12 protein networkhttps://string-db.org/network/284812.Q9UT16Protein atp12, mitochondrial; Essential for the assembly of the mitochondrial F1-F0 complex; Belongs to the ATP12 family.
thi9 protein networkhttps://string-db.org/network/284812.Q9UT18Thiamine transporter thi9; Thiamine transporter involved in the cellular uptake of thiamine. Pyrithiamine, oxythiamine, amprolium, and the thiazole part of thiamine have been shown to be also sub [...]
met26 protein networkhttps://string-db.org/network/284812.Q9UT19Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine for [...]
SPAC9.08c protein networkhttps://string-db.org/network/284812.Q9UT20Uncharacterized protein C9.08c.
SPAC9.07c protein networkhttps://string-db.org/network/284812.Q9UT21Uncharacterized GTP-binding protein C9.07c; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
SPAC9.06c protein networkhttps://string-db.org/network/284812.Q9UT22Methylthioribulose-1-phosphate dehydratase-like protein; Belongs to the aldolase class II family. MtnB subfamily.
fml1 protein networkhttps://string-db.org/network/284812.Q9UT23ATP-dependent DNA helicase fml1; ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limi [...]
brr2 protein networkhttps://string-db.org/network/284812.Q9UT24Pre-mRNA-splicing factor brr2; Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures ( [...]
SPAC9.02c protein networkhttps://string-db.org/network/284812.Q9UT25Uncharacterized N-acetyltransferase C9.02c; Belongs to the acetyltransferase family.
pvg1 protein networkhttps://string-db.org/network/284812.Q9UT27Pyruvyl transferase 1; Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moieties to galactomannans and their subsequent pyruvylation.
nnt1 protein networkhttps://string-db.org/network/284812.Q9UT28Protein N-terminal and lysine N-methyltransferase efm7; S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, [...]
SPAC8F11.08c protein networkhttps://string-db.org/network/284812.Q9UT29Uncharacterized protein C8F11.08c; Has a role in meiotic chromosome segregation.
brr6 protein networkhttps://string-db.org/network/284812.Q9UT30Nucleus export protein brr6; Involved in mRNA and protein export from nucleus. Belongs to the BRL1/BRR6 family.
SPAC8F11.04 protein networkhttps://string-db.org/network/284812.Q9UT32Putative ribosome biogenesis protein C8F11.04; Involved in rRNA-processing and ribosome biosynthesis.
dph3 protein networkhttps://string-db.org/network/284812.Q9UT33Diphthamide biosynthesis protein 3; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthami [...]
SPAC824.09c protein networkhttps://string-db.org/network/284812.Q9UT34Uncharacterized protein C824.09c; GTPase-activating protein for the ADP ribosylation factor family.
gda1 protein networkhttps://string-db.org/network/284812.Q9UT35Guanosine-diphosphatase; After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lum [...]
glo2 protein networkhttps://string-db.org/network/284812.Q9UT36Probable hydroxyacylglutathione hydrolase C824.07; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
tim14 protein networkhttps://string-db.org/network/284812.Q9UT37Mitochondrial import inner membrane translocase subunit tim14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inn [...]
vps16 protein networkhttps://string-db.org/network/284812.Q9UT38Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology (By similari [...]
swd22 protein networkhttps://string-db.org/network/284812.Q9UT39Uncharacterized WD repeat-containing protein C824.04.
bst1 protein networkhttps://string-db.org/network/284812.Q9UT41GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
lsb6 protein networkhttps://string-db.org/network/284812.Q9UT42Phosphatidylinositol 4-kinase lsb6; May play a role in endocytic and/or exocytic pathways. Belongs to the PI3/PI4-kinase family.
dnf1 protein networkhttps://string-db.org/network/284812.Q9UT43Putative phospholipid-transporting ATPase C821.13c; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
pro1 protein networkhttps://string-db.org/network/284812.Q9UT44Probable gamma-glutamyl phosphate reductase; Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously under [...]
eng1 protein networkhttps://string-db.org/network/284812.Q9UT45Endo-1,3(4)-beta-glucanase 1; Has a role in cell separation where it is required for the degradation of the primary septum after completion of cytokinesis.
moc3 protein networkhttps://string-db.org/network/284812.Q9UT46Transcriptional regulatory protein moc3; Induces sexual development and ascus formation. Also involved in calcium homeostasis.
tif308 protein networkhttps://string-db.org/network/284812.Q9UT48Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoi [...]
cid13 protein networkhttps://string-db.org/network/284812.Q9UT49Poly(A) RNA polymerase cid13; Polymerase that creates the 3' poly(A) tail of suc22 mRNA.
slf1 protein networkhttps://string-db.org/network/284812.Q9UT50Uncharacterized protein C821.03c.
csn3 protein networkhttps://string-db.org/network/284812.Q9UT51COP9 signalosome complex subunit 3; Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cull [...]
mod21 protein networkhttps://string-db.org/network/284812.Q9UT52Gamma-tubulin complex subunit mod21; Component of the gamma-tubulin complex that is required for the regulation of both interphase microtubule organization and nucleation, and mitotic bipolar spi [...]
SPAC806.06c protein networkhttps://string-db.org/network/284812.Q9UT53Nicotinamide/nicotinic acid mononucleotide adenylyltransferase; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid [...]
duf8901 protein networkhttps://string-db.org/network/284812.Q9UT55Damage-control phosphatase SPAC806.04c; Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate (By similar [...]
rps2601 protein networkhttps://string-db.org/network/284812.Q9UT5640S ribosomal protein S26-A.
SPAC806.02c protein networkhttps://string-db.org/network/284812.Q9UT57Probable cytosolic Fe-S cluster assembly factor SPAC806.02c; Fusion protein of two essential components of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturati [...]
SPAC513.07 protein networkhttps://string-db.org/network/284812.Q9UT59Putative uncharacterized oxidoreductase C513.07.
dhd1 protein networkhttps://string-db.org/network/284812.Q9UT60Probable D-xylose 1-dehydrogenase (NADP(+)); NADP-dependent D-xylose dehydrogenase catalyzing the oxydation of D-xylose into D-xylonolactone (By similarity). May also display activity with other [...]
ams1 protein networkhttps://string-db.org/network/284812.Q9UT61Alpha-mannosidase; Degrades free oligosaccharides in the vacuole; Belongs to the glycosyl hydrolase 38 family.
SPAC513.04 protein networkhttps://string-db.org/network/284812.Q9UT62Uncharacterized protein C513.04.
SPAC513.02 protein networkhttps://string-db.org/network/284812.Q9UT63Probable phosphatase SPAC513.02.
imt2 protein networkhttps://string-db.org/network/284812.Q9UT67Inositol phosphoceramide mannosyltransferase 2; With imt1 and imt3, is required for the synthesis of mannosyl phosphorylinositol ceramide (MIPC). Catalyzes the addition of mannosyl to phosphoryli [...]
SPCC4F11.03c protein networkhttps://string-db.org/network/284812.Q9UT68Uncharacterized protein C4F11.03c.
bet5 protein networkhttps://string-db.org/network/284812.Q9UT70Transport protein particle subunit bet5; May play a role in vesicular transport from endoplasmic reticulum to Golgi.
rfp2 protein networkhttps://string-db.org/network/284812.Q9UT72E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp2; Mediates ubiquitination and subsequent desumoylation/degradation of sumoylated proteins and proteins containing SUMO-like domains. Invol [...]
wdr70 protein networkhttps://string-db.org/network/284812.Q9UT73Uncharacterized WD repeat-containing protein C343.17c.
lys2 protein networkhttps://string-db.org/network/284812.Q9UT74Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
tit1 protein networkhttps://string-db.org/network/284812.Q9UT75tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethyla [...]
tif222 protein networkhttps://string-db.org/network/284812.Q9UT76Probable translation initiation factor eIF-2B subunit beta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family.
gta2 protein networkhttps://string-db.org/network/284812.Q9UT77Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. [...]
msc1 protein networkhttps://string-db.org/network/284812.Q9UT79Multicopy suppressor of chk1 protein 1; Has a role in regulating chromatin structure via global deacetylation of histone H3. This function is associated with the activity of a histone deacetylase [...]
ubx3 protein networkhttps://string-db.org/network/284812.Q9UT81UBX domain-containing protein 3; Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway. Involved in delivery of substrates to the 26S proteasome. Also required [...]
mrp17 protein networkhttps://string-db.org/network/284812.Q9UT8237S ribosomal protein MRP17, mitochondrial; Belongs to the bacterial ribosomal protein bS6 family.
mug28 protein networkhttps://string-db.org/network/284812.Q9UT83Meiotically up-regulated gene 28 protein; Has a role in sporulation.
SPAC343.06c protein networkhttps://string-db.org/network/284812.Q9UT84Phospholipid scramblase family protein C343.06c.
gid7 protein networkhttps://string-db.org/network/284812.Q9UT85Uncharacterized WD repeat-containing protein C343.04c.
apc11 protein networkhttps://string-db.org/network/284812.Q9UT86Anaphase-promoting complex subunit 11; Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through [...]
img1 protein networkhttps://string-db.org/network/284812.Q9UT8754S ribosomal protein subunit img1, mitochondrial.
erg8 protein networkhttps://string-db.org/network/284812.Q9UT88Probable phosphomevalonate kinase.
rmp1 protein networkhttps://string-db.org/network/284812.Q9UT91Ribonuclease MRP protein subunit rmp1; Functions as part of ribonuclease MRP (RNase MRP), which is involved in rRNA processing in mitochondria.
SPAC323.07c protein networkhttps://string-db.org/network/284812.Q9UT92Uncharacterized transporter C323.07c.
uba5 protein networkhttps://string-db.org/network/284812.Q9UT93NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric uba3-ula1 E1 enzyme. E1 activates NEDD8/ubl1 by first adenylating its C-terminal glycine residue with ATP, thereaf [...]
mtq2 protein networkhttps://string-db.org/network/284812.Q9UT94eRF1 methyltransferase catalytic subunit mtq2; Methylates eRF1 on 'Gln-182' using S-adenosyl L-methionine as methyl donor. eRF1 needs to be complexed to eRF3 in its GTP-bound form to be efficient [...]
SPAC323.04 protein networkhttps://string-db.org/network/284812.Q9UT95Uncharacterized ABC transporter ATP-binding protein C323.04.
pex8 protein networkhttps://string-db.org/network/284812.Q9UT96Uncharacterized protein C323.03c.
pup2 protein networkhttps://string-db.org/network/284812.Q9UT97Probable proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent [...]
pos5 protein networkhttps://string-db.org/network/284812.Q9UT98NADH kinase pos5, mitochondrial; Phosphorylates both NADH and NAD(+), with a preference for NADH. Anti-oxidant factor and key source of the cellular reductant NADPH (By similarity).
SPAC27E2.11c protein networkhttps://string-db.org/network/284812.Q9UTA0Uncharacterized protein C27E2.11c, mitochondrial.
loz1 protein networkhttps://string-db.org/network/284812.Q9UTA1Zinc finger protein C25B8.19c.
ypf1 protein networkhttps://string-db.org/network/284812.Q9UTA3Probable intramembrane protease C25B8.17; Belongs to the peptidase A22B family.
pop100 protein networkhttps://string-db.org/network/284812.Q9UTA4Ribonucleases P/MRP protein subunit pop1; Required for processing of 5.8S rRNA (short form) at site A3 and for 5' and 3' processing of pre-tRNA; Belongs to the POP1 family.
tyw3 protein networkhttps://string-db.org/network/284812.Q9UTA5tRNA wybutosine-synthesizing protein 3; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosi [...]
SPAC25B8.12c protein networkhttps://string-db.org/network/284812.Q9UTA6Uncharacterized hydrolase C25B8.12c.
SPAC25B8.10 protein networkhttps://string-db.org/network/284812.Q9UTA8Uncharacterized methyltransferase-like C25B8.10; Probable methyltransferase; Belongs to the methyltransferase superfamily.
SPAC25B8.09 protein networkhttps://string-db.org/network/284812.Q9UTA9Uncharacterized methyltransferase C25B8.09; Probable methyltransferase; Belongs to the methyltransferase superfamily.
SPAC25B8.08 protein networkhttps://string-db.org/network/284812.Q9UTB0Dilute domain-containing protein C25B8.08.
rcf1 protein networkhttps://string-db.org/network/284812.Q9UTB1HIG1 domain-containing protein C25B8.07c, mitochondrial.
dia4 protein networkhttps://string-db.org/network/284812.Q9UTB2Serine--tRNA ligase, mitochondrial; Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), w [...]
deg1 protein networkhttps://string-db.org/network/284812.Q9UTB3Putative tRNA pseudouridine synthase C25B8.05; Belongs to the tRNA pseudouridine synthase TruA family.
mss51 protein networkhttps://string-db.org/network/284812.Q9UTB4Protein mss51; Has a dual role in the assembly of cytochrome oxidase subunit 1 (cox1). It has a regulative function on cox1 synthesis, acting as a translational activator specific for the cox1 mR [...]
psd2 protein networkhttps://string-db.org/network/284812.Q9UTB5Phosphatidylserine decarboxylase proenzyme 2, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid me [...]
sds3 protein networkhttps://string-db.org/network/284812.Q9UTB6Transcriptional regulatory protein sds3; Component of the clr6 histone deacetylase complex I responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, [...]
ini1 protein networkhttps://string-db.org/network/284812.Q9UTB8Pre-mRNA-splicing factor ini1; Required for pre-mRNA splicing. Belongs to the PHF5 family.
zym1 protein networkhttps://string-db.org/network/284812.Q9UTC0Metallothionein zym1; Metallothionein involved in tolerance to zinc and cadmium.
SPAC227.17c protein networkhttps://string-db.org/network/284812.Q9UTC2Uncharacterized protein C227.17c.
psf3 protein networkhttps://string-db.org/network/284812.Q9UTC3DNA replication complex GINS protein psf3; The GINS complex plays an essential role in the initiation of DNA replication.
reg1 protein networkhttps://string-db.org/network/284812.Q9UTC4Uncharacterized protein C227.15.
yfh7 protein networkhttps://string-db.org/network/284812.Q9UTC5Putative uridine kinase C227.14.
isu1 protein networkhttps://string-db.org/network/284812.Q9UTC6Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mito [...]
rna4 protein networkhttps://string-db.org/network/284812.Q9UTC7Uncharacterized WD repeat-containing protein C227.12.
yos9 protein networkhttps://string-db.org/network/284812.Q9UTC8Protein OS-9 homolog; Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, target [...]
pfd2 protein networkhttps://string-db.org/network/284812.Q9UTC9Probable prefoldin subunit 2; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in [...]
fol3 protein networkhttps://string-db.org/network/284812.Q9UTD0Probable dihydrofolate synthetase; Glutamate-adding enzyme which catalyzes the binding of the first glutamyl side chain to dihydropteroate. Leads to the de nove synthesis of tetrahydrofolate. de [...]
yth1 protein networkhttps://string-db.org/network/284812.Q9UTD1mRNA 3'-end-processing protein yth1; Component of the cleavage factor I (CF I) involved in pre- mRNA 3'-end processing; Belongs to the CPSF4/YTH1 family.
yip5 protein networkhttps://string-db.org/network/284812.Q9UTD3Protein YIP5; Possible role in vesicle-mediated transport. May be involved in proper membrane localization of Rab GTPases (By similarity).
pfd4 protein networkhttps://string-db.org/network/284812.Q9UTD4Probable prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in [...]
atg10 protein networkhttps://string-db.org/network/284812.Q9UTD5Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy and nucleophagy. Acts as an E2-like enzyme that catalyzes the conjugation [...]
rrp15 protein networkhttps://string-db.org/network/284812.Q9UTD7Ribosomal RNA-processing protein 15; Constituent of pre-60S ribosomal particles. Required for large subunit rRNA maturation (By similarity); Belongs to the RRP15 family.
erd1 protein networkhttps://string-db.org/network/284812.Q9UTD8Protein ERD1 homolog 1; Required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus. Belongs to the ERD1 family.
sey1 protein networkhttps://string-db.org/network/284812.Q9UTE0Protein sey1; Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activit [...]
SPAC222.13c protein networkhttps://string-db.org/network/284812.Q9UTE1Probable 6-phosphofructo-2-kinase C222.13c; Synthesis of fructose 2,6-bisphosphate.
hem13 protein networkhttps://string-db.org/network/284812.Q9UTE2Probable oxygen-dependent coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyri [...]
seb1 protein networkhttps://string-db.org/network/284812.Q9UTE3Rpb7-binding protein seb1; Involved in the processing of pol II transcripts.
sno1 protein networkhttps://string-db.org/network/284812.Q9UTE4Uncharacterized glutaminase C222.08c; Belongs to the glutaminase PdxT/SNO family.
hri2 protein networkhttps://string-db.org/network/284812.Q9UTE5Eukaryotic translation initiation factor 2-alpha kinase 2; Mediates down-regulation of protein synthesis in response to stress conditions by the phosphorylation of the alpha subunit of eIF-2 (tif [...]
mak16 protein networkhttps://string-db.org/network/284812.Q9UTE6Protein mak16.
mss1 protein networkhttps://string-db.org/network/284812.Q9UTE7tRNA modification GTPase mss1, mitochondrial; GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs; Belongs to the TRAF [...]
ies6 protein networkhttps://string-db.org/network/284812.Q9UTE8Chromatin-remodeling complex subunit ies6; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Also involved in the regulatio [...]
tim10 protein networkhttps://string-db.org/network/284812.Q9UTE9Mitochondrial import inner membrane translocase subunit tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mi [...]
cox6 protein networkhttps://string-db.org/network/284812.Q9UTF6Cytochrome c oxidase subunit 6, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The res [...]
elo2 protein networkhttps://string-db.org/network/284812.Q9UTF7Putative elongation of fatty acids protein 1; May be involved in the synthesis of very long chain fatty acids.
ugo1 protein networkhttps://string-db.org/network/284812.Q9UTF8Mitochondrial fusion and transport protein ugo1; Required for mitochondrial fusion as well as normal mitochondrial morphology. May coordinate fusion of inner and outer membranes during mitochondr [...]
SPAC1805.16c protein networkhttps://string-db.org/network/284812.Q9UTG1Putative purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with th [...]
pub2 protein networkhttps://string-db.org/network/284812.Q9UTG2E3 ubiquitin-protein ligase pub2; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin [...]
SPAC1805.14 protein networkhttps://string-db.org/network/284812.Q9UTG3Uncharacterized protein C1805.14.
rps2602 protein networkhttps://string-db.org/network/284812.Q9UTG440S ribosomal protein S26-B.
fmt1 protein networkhttps://string-db.org/network/284812.Q9UTG6Putative methionyl-tRNA formyltransferase; Formylates methionyl-tRNA in mitochondria and the cytoplasm. Responsible for the formylation of the N-terminally formylated (Nt- formylated) mitochondri [...]
dad2 protein networkhttps://string-db.org/network/284812.Q9UTG8DASH complex subunit dad2; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates [...]
nup132 protein networkhttps://string-db.org/network/284812.Q9UTH0Nucleoporin nup132; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural component [...]
trm13 protein networkhttps://string-db.org/network/284812.Q9UTH1tRNA:m(4)X modification enzyme TRM13; tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
etf2 protein networkhttps://string-db.org/network/284812.Q9UTH2Probable electron transfer flavoprotein subunit beta; The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, [...]
ppk6 protein networkhttps://string-db.org/network/284812.Q9UTH3Serine/threonine-protein kinase ppk6.
plb2 protein networkhttps://string-db.org/network/284812.Q9UTH5Probable lysophospholipase C1786.02; Catalyzes the release of fatty acids from lysophospholipids.
sfp1 protein networkhttps://string-db.org/network/284812.Q9UTH8Zinc finger protein sfp1.
dus3 protein networkhttps://string-db.org/network/284812.Q9UTH9tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
ura2 protein networkhttps://string-db.org/network/284812.Q9UTI0Probable dihydroorotase.
fub1 protein networkhttps://string-db.org/network/284812.Q9UTI1Silencing boundary-establishment protein FUB1-like protein; May play a role in the establishment of transcriptional silencing boundaries, preventing the propagation of heterochromatic silencing.
grx2 protein networkhttps://string-db.org/network/284812.Q9UTI2Glutaredoxin-2; The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also [...]
naa10 protein networkhttps://string-db.org/network/284812.Q9UTI3N-terminal acetyltransferase A complex catalytic subunit ard1; Catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gl [...]
moa1 protein networkhttps://string-db.org/network/284812.Q9UTI4Monopolar attachment protein 1; Plays an important role in chromosome segregation during meiosis I by allowing meiotic rec8 to establish cohesion at the centromeric central core and thereby promo [...]
vps29 protein networkhttps://string-db.org/network/284812.Q9UTI5Vacuolar protein sorting-associated protein 29; Plays a role in vesicular protein sorting. Required for the endosome-to-Golgi retrieval of the vacuolar protein sorting receptor pep1/vps10. Compon [...]
ect1 protein networkhttps://string-db.org/network/284812.Q9UTI6Probable ethanolamine-phosphate cytidylyltransferase; Belongs to the cytidylyltransferase family.
hal3 protein networkhttps://string-db.org/network/284812.Q9UTI7Probable thymidylate synthase; Required for both nuclear and mitochondrial DNA synthesis. In the N-terminal section; belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) sup [...]
rpl42 protein networkhttps://string-db.org/network/284812.Q9UTI860S ribosomal protein L42; Belongs to the eukaryotic ribosomal protein eL42 family.
SPAC15E1.02c protein networkhttps://string-db.org/network/284812.Q9UTI9UPF0591 membrane protein C15E1.02c.
pmm1 protein networkhttps://string-db.org/network/284812.Q9UTJ2Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
meu1 protein networkhttps://string-db.org/network/284812.Q9UTJ3Meiotic expression up-regulated protein 1/2.
cgr1 protein networkhttps://string-db.org/network/284812.Q9UTJ4rRNA-processing protein cgr1; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit; Belongs to the CGR1 family.
sdh1 protein networkhttps://string-db.org/network/284812.Q9UTJ7Probable succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial e [...]
rad50 protein networkhttps://string-db.org/network/284812.Q9UTJ8DNA repair protein rad50; Involved in DNA double-strand break (DSB) repair. Involved in mating type switching and has a role in choosing the sister chromatid for recombinational repair. Also has [...]
nob1 protein networkhttps://string-db.org/network/284812.Q9UTK020S-pre-rRNA D-site endonuclease nob1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at th [...]
cox16 protein networkhttps://string-db.org/network/284812.Q9UTK1Cytochrome c oxidase assembly protein cox16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate [...]
mrpl19 protein networkhttps://string-db.org/network/284812.Q9UTK254S ribosomal protein L19, mitochondrial; Belongs to the universal ribosomal protein uL11 family.
npt1 protein networkhttps://string-db.org/network/284812.Q9UTK3Probable nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicot [...]
nup189 protein networkhttps://string-db.org/network/284812.Q9UTK4Nucleoporin nup189; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural component [...]
alm1 protein networkhttps://string-db.org/network/284812.Q9UTK5Abnormal long morphology protein 1; After the onset of mitosis, at mid- to late anaphase, colocalizes with the medial actin ring. May play a role in cytokinesis.
ntr1 protein networkhttps://string-db.org/network/284812.Q9UTK6G-patch domain-containing protein C1486.03.
dsc2 protein networkhttps://string-db.org/network/284812.Q9UTK7DSC E3 ubiquitin ligase complex subunit 2; Component of the DSC E3 ubiquitin ligase complex which is required for the sre1 transcriptional activator proteolytic cleavage to release the soluble tr [...]
vrg4 protein networkhttps://string-db.org/network/284812.Q9UTK8GDP-mannose transporter; Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
SPAC144.17c protein networkhttps://string-db.org/network/284812.Q9UTK9Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase C144.17c; Synthesis and degradation of fructose 2,6-bisphosphate.
cia2 protein networkhttps://string-db.org/network/284812.Q9UTL0MIP18 family protein C144.16; May play a role in chromosome segregation through establishment of sister chromatid cohesion.
cog1 protein networkhttps://string-db.org/network/284812.Q9UTL1Conserved oligomeric Golgi complex subunit 1; Acts as essential component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Gol [...]
klp8 protein networkhttps://string-db.org/network/284812.Q9UTL2Kinesin-like protein 8.
rki1 protein networkhttps://string-db.org/network/284812.Q9UTL3Ribose-5-phosphate isomerase.
gwt1 protein networkhttps://string-db.org/network/284812.Q9UTL4GPI-anchored wall transfer protein 1; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor (By similarity). Has a role in meios [...]
sfc2 protein networkhttps://string-db.org/network/284812.Q9UTL5Transcription factor IIIA; Is required for correct transcription of 5S RNA genes by RNA polymerase III. Also binds the transcribed 5S RNA's. Initiates transcription of the 5S ribosomal RNA gene.
jac1 protein networkhttps://string-db.org/network/284812.Q9UTL6J-type co-chaperone jac1, mitochondrial; Co-chaperone required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria. Stimulates the ATPase activity of the mitochondrial Hsp70 chaperone [...]
gpn2 protein networkhttps://string-db.org/network/284812.Q9UTL7GPN-loop GTPase 2; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.
apl5 protein networkhttps://string-db.org/network/284812.Q9UTL8AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral struc [...]
SPAC144.05 protein networkhttps://string-db.org/network/284812.Q9UTL9Uncharacterized ATP-dependent helicase C144.05.
iec1 protein networkhttps://string-db.org/network/284812.Q9UTM0INO80 complex subunit 1; Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
SPAC144.01 protein networkhttps://string-db.org/network/284812.Q9UTM1Uncharacterized protein C144.01.
cox1101 protein networkhttps://string-db.org/network/284812.Q9UTM2Cytochrome c oxidase assembly protein cox11-1; Rsm22-1 is involved in mitochondrion-encoded protein synthesis; In the C-terminal section; belongs to the COX11/CtaG family.
cct5 protein networkhttps://string-db.org/network/284812.Q9UTM4T-complex protein 1 subunit epsilon; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
SPAC1420.01c protein networkhttps://string-db.org/network/284812.Q9UTM5Uncharacterized protein C1420.01c.
hat1 protein networkhttps://string-db.org/network/284812.Q9UTM7Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. Ha [...]
SPAC139.05 protein networkhttps://string-db.org/network/284812.Q9UTM8Putative succinate-semialdehyde dehydrogenase C139.05 [NADP(+)]; Belongs to the aldehyde dehydrogenase family.
fap2 protein networkhttps://string-db.org/network/284812.Q9UTM9L-saccharopine oxidase.
toe2 protein networkhttps://string-db.org/network/284812.Q9UTN0Uncharacterized transcriptional regulatory protein C139.03.
oac1 protein networkhttps://string-db.org/network/284812.Q9UTN1Mitochondrial oxaloacetate transport protein; Transports oxaloacetate and sulfate; Belongs to the mitochondrial carrier (TC 2.A.29) family.
mkt1 protein networkhttps://string-db.org/network/284812.Q9UTN2Uncharacterized protein C139.01c.
cid14 protein networkhttps://string-db.org/network/284812.Q9UTN3Poly(A) RNA polymerase cid14; Required for 3' polyadenylation of the 5.8S and 25S rRNAs as a prelude to their degradation in the exosome. Involved in the nucleolar organization to ensure faithful [...]
pfs2 protein networkhttps://string-db.org/network/284812.Q9UTN4Polyadenylation factor subunit 2; Required for 3'-end cleavage and polyadenylation of pre- mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitot [...]
snf21 protein networkhttps://string-db.org/network/284812.Q9UTN6Chromatin structure-remodeling complex subunit snf21; Helicase. Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positio [...]
ubc14 protein networkhttps://string-db.org/network/284812.Q9UTN8Ubiquitin-conjugating enzyme E2 14; Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins.
atl1 protein networkhttps://string-db.org/network/284812.Q9UTN9Alkyltransferase-like protein 1; Involved in DNA damage recognition. Binds DNA containing O(6)-methylguanine and larger O(6)-alkylguanine adducts. The DNA is bent, the damaged base is rotated out [...]
rpl3002 protein networkhttps://string-db.org/network/284812.Q9UTP060S ribosomal protein L30-2.
fta6 protein networkhttps://string-db.org/network/284812.Q9UTP3Inner kinetochore subunit fta6; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segre [...]
SPAC11H11.03c protein networkhttps://string-db.org/network/284812.Q9UTP4Smr domain-containing protein C11H11.03c.
hca4 protein networkhttps://string-db.org/network/284812.Q9UTP9ATP-dependent RNA helicase dbp4; ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at s [...]
cca1 protein networkhttps://string-db.org/network/284812.Q9UTQ0tRNA nucleotidyltransferase cca1; tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus. In contrast to what is usually observed in eukaryotes for which one enzyme synthe [...]
pdx3 protein networkhttps://string-db.org/network/284812.Q9UTQ1Probable pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
SPAC1071.11 protein networkhttps://string-db.org/network/284812.Q9UTQ4Uncharacterized protein C1071.11.
SPAC1071.09c protein networkhttps://string-db.org/network/284812.Q9UTQ5Uncharacterized J domain-containing protein C1071.09c.
rps1502 protein networkhttps://string-db.org/network/284812.Q9UTQ640S ribosomal protein S15-B.
arp9 protein networkhttps://string-db.org/network/284812.Q9UTQ7SWI/SNF and RSC complexes subunit arp9; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particula [...]
hpm1 protein networkhttps://string-db.org/network/284812.Q9UTQ8Histidine protein methyltransferase 1; Required for histidine methylation of RPL3 at 'His-243'.
spc2 protein networkhttps://string-db.org/network/284812.Q9UTQ9Signal peptidase complex subunit spc2; Nonessential component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endopl [...]
mms19 protein networkhttps://string-db.org/network/284812.Q9UTR1DNA repair/transcription protein mms19; Key component of the cytosolic iron-sulfur protein assembly (CIA) machinery that mediates the incorporation of iron-sulfur cluster into apoproteins specifi [...]
etd1 protein networkhttps://string-db.org/network/284812.Q9UTR4Septation protein etd1; Involved in septation.
rgf2 protein networkhttps://string-db.org/network/284812.Q9UTR5Rho1 guanine nucleotide exchange factor 2; Stimulates the exchange of Rho1 and Rho5 GDP-bound form into GTP-bound form. Controls septum formation, cell wall synthesis and localization of F-actin [...]
och1 protein networkhttps://string-db.org/network/284812.Q9UTR6Initiation-specific alpha-1,6-mannosyltransferase; Mannosyltransferase involved in outer chain elongation of asparagine-linked oligosaccharides of the type Man(9)GlcNAc(2). May otherwise add the [...]
mcp3 protein networkhttps://string-db.org/network/284812.Q9UTR7Meiotic coiled-coil protein 3; Has a role in meiosis.
red1 protein networkhttps://string-db.org/network/284812.Q9UTR8Protein red1; Required for elimination of meiosis-specific mRNAs from mitotic cells. Promotes the destabilization of mRNAs containing a degradation signal sequence called determinant of selective [...]
asa1 protein networkhttps://string-db.org/network/284812.Q9UTR9ASTRA-associated protein 1; Component of the ASTRA complex probably involved in chromatin remodeling.
psp3 protein networkhttps://string-db.org/network/284812.Q9UTS0Subtilase-type proteinase psp3; Belongs to the peptidase S8 family.
zas1 protein networkhttps://string-db.org/network/284812.Q9UTS5Zinc finger protein zas1.
dlc1 protein networkhttps://string-db.org/network/284812.Q9UTS6Dynein light chain Tctex-type; Acts as a non-catalytic accessory component of a dynein complex.
SPAC977.12 protein networkhttps://string-db.org/network/284812.Q9UTS7Probable L-asparaginase 2; Belongs to the asparaginase 1 family.
ubp15 protein networkhttps://string-db.org/network/284812.Q9UTT1Ubiquitin carboxyl-terminal hydrolase 21; Involved in regulating the steady-state levels of proteins including prp4.
prp12 protein networkhttps://string-db.org/network/284812.Q9UTT2Pre-mRNA-splicing factor prp12; Involved in mRNA splicing and G2/M transition.
puf6 protein networkhttps://string-db.org/network/284812.Q9UU76Pumilio homology domain family member 6; RNA-binding protein involved in post-transcriptional regulation; Belongs to the PUF6 family.
dhm1 protein networkhttps://string-db.org/network/284812.Q9UU77Ankyrin repeat-containing protein P1E11.10.
rpp103 protein networkhttps://string-db.org/network/284812.Q9UU7860S acidic ribosomal protein P1-alpha 5; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family.
nsa2 protein networkhttps://string-db.org/network/284812.Q9UU79Ribosome biogenesis protein nsa2; Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity).
cwf18 protein networkhttps://string-db.org/network/284812.Q9UU80Pre-mRNA-splicing factor cwf18; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
apl4 protein networkhttps://string-db.org/network/284812.Q9UU81AP-1 complex subunit gamma-1; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact [...]
are2 protein networkhttps://string-db.org/network/284812.Q9UU82Probable sterol O-acyltransferase 2.
pal1 protein networkhttps://string-db.org/network/284812.Q9UU83Protein pal1; Involved in cellular morphogenesis and cell wall integrity. Important for the maintenance of a cylindrical cell shape.
mug170 protein networkhttps://string-db.org/network/284812.Q9UU84Meiotically up-regulated gene 170 protein; Has a role in meiosis; Belongs to the arrestin family.
ppk38 protein networkhttps://string-db.org/network/284812.Q9UU85Protein kinase domain-containing protein ppk38.
SPCC1827.07c protein networkhttps://string-db.org/network/284812.Q9UU86Protein SYG1 homolog; May function in G-protein coupled signal transduction. Belongs to the SYG1 (TC 2.A.94) family.
ckk2 protein networkhttps://string-db.org/network/284812.Q9UU87Serine/threonine-protein kinase ppk34.
fap7 protein networkhttps://string-db.org/network/284812.Q9UU88Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphat [...]
ham1 protein networkhttps://string-db.org/network/284812.Q9UU89Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-tripho [...]
pop5 protein networkhttps://string-db.org/network/284812.Q9UU90Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP, which cleave [...]
yop1 protein networkhttps://string-db.org/network/284812.Q9UU91Protein yop1; Required for the correct positioning of the cellular division plane by delimiting the actomyosin ring assembly at the cell equator.
cnb1 protein networkhttps://string-db.org/network/284812.Q9UU93Calcineurin subunit B; Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity (By similarity).
epl1 protein networkhttps://string-db.org/network/284812.Q9UU94Enhancer of polycomb-like protein 1; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleo [...]
grc3 protein networkhttps://string-db.org/network/284812.Q9UU96Polynucleotide 5'-hydroxyl-kinase grc3; Polynucleotide 5'-kinase required for both rRNA processing and heterochromatic gene silencing.
pdr16 protein networkhttps://string-db.org/network/284812.Q9UU99CRAL-TRIO domain-containing protein C23B6.04c.
SPCC23B6.02c protein networkhttps://string-db.org/network/284812.Q9UUA0Shuttling pre-60S factor C23B6.02c; Pre-ribosomal factor involved in 60S ribosomal protein subunit export from the nucleus.
osh6 protein networkhttps://string-db.org/network/284812.Q9UUA1Oxysterol-binding protein homolog C23B6.01c.
pfh1 protein networkhttps://string-db.org/network/284812.Q9UUA2ATP-dependent DNA helicase pfh1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Involved in the maintenance of mitoch [...]
sec66 protein networkhttps://string-db.org/network/284812.Q9UUA4Translocation protein sec66; Acts as component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions to [...]
mtx1 protein networkhttps://string-db.org/network/284812.Q9UUA5Metaxin-like protein C409.19c; May be involved in transport of proteins into the mitochondrion; Belongs to the metaxin family.
SPBC409.18 protein networkhttps://string-db.org/network/284812.Q9UUA6Probable diacylglycerol pyrophosphate phosphatase 1; Catalyzes the dephosphorylation of diacylglycerol phosphate (DGPP) to phosphatidate (PA) and the subsequent dephosphorylation of PA to diacylg [...]
saw1 protein networkhttps://string-db.org/network/284812.Q9UUA8Uncharacterized protein C409.16c.
tsr2 protein networkhttps://string-db.org/network/284812.Q9UUA9Pre-rRNA-processing protein tsr2; Required for 20S pre-rRNA processing; Belongs to the TSR2 family.
mrps17 protein networkhttps://string-db.org/network/284812.Q9UUB037S ribosomal protein S17, mitochondrial; Belongs to the universal ribosomal protein uS17 family.
rib4 protein networkhttps://string-db.org/network/284812.Q9UUB16,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
meu18 protein networkhttps://string-db.org/network/284812.Q9UUB3Meiotic expression up-regulated protein 18.
ade7 protein networkhttps://string-db.org/network/284812.Q9UUB4Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.
mis13 protein networkhttps://string-db.org/network/284812.Q9UUB5Kinetochore protein mis13; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cyc [...]
uch2 protein networkhttps://string-db.org/network/284812.Q9UUB6Ubiquitin carboxyl-terminal hydrolase 2; Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that [...]
swi5 protein networkhttps://string-db.org/network/284812.Q9UUB7Mating-type switching protein swi5; Required for normal mating-type switching. Also involved in the rhp51-dependent recombination DNA repair pathway.
nfu1 protein networkhttps://string-db.org/network/284812.Q9UUB8NifU-like protein C1709.19c; Belongs to the NifU family.
rpl2101 protein networkhttps://string-db.org/network/284812.Q9UUC160S ribosomal protein L21-A.
smd3 protein networkhttps://string-db.org/network/284812.Q9UUC6Small nuclear ribonucleoprotein Sm D3; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site (By similarity).
ctu2 protein networkhttps://string-db.org/network/284812.Q9UUC7Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with [...]
mrpl51 protein networkhttps://string-db.org/network/284812.Q9UUC854S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL43 family.
mdm34 protein networkhttps://string-db.org/network/284812.Q9UUC9Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components [...]
SPBC19C2.10 protein networkhttps://string-db.org/network/284812.Q9UUD0Uncharacterized protein C19C2.10.
sre1 protein networkhttps://string-db.org/network/284812.Q9UUD1Processed sterol regulatory element-binding protein 1; Transcriptional activator required for transcription of genes required for adaptation to anaerobic growth like those implicated in the nonre [...]
prp38 protein networkhttps://string-db.org/network/284812.Q9UUD2Pre-mRNA-splicing factor 38; Required for pre-mRNA splicing and maintenance of stable U6 small nuclear RNA levels. Implicated in the formation of stable and biologically active snRNP structures. [...]
ubp11 protein networkhttps://string-db.org/network/284812.Q9UUD6Ubiquitin carboxyl-terminal hydrolase 11.
xpa1 protein networkhttps://string-db.org/network/284812.Q9UUD8Uncharacterized peptidase C18A7.01.
cup1 protein networkhttps://string-db.org/network/284812.Q9UUD9Uncharacterized protein C17G9.13c.
SPBC17G9.12c protein networkhttps://string-db.org/network/284812.Q9UUE0CTO1 family protein C17G9.12c.
pyr1 protein networkhttps://string-db.org/network/284812.Q9UUE1Pyruvate carboxylase; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carbo [...]
cnt5 protein networkhttps://string-db.org/network/284812.Q9UUE2Protein csx2.
sib3 protein networkhttps://string-db.org/network/284812.Q9UUE3Putative lysine N-acyltransferase C17G9.06c.
rct1 protein networkhttps://string-db.org/network/284812.Q9UUE4Peptidyl-prolyl cis-trans isomerase cyp6; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Be [...]
nup85 protein networkhttps://string-db.org/network/284812.Q9UUE5Nucleoporin nup85; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components [...]
krs1 protein networkhttps://string-db.org/network/284812.Q9UUE6Lysine--tRNA ligase, cytoplasmic.
cdc73 protein networkhttps://string-db.org/network/284812.Q9UUE7Cell division control protein 73; The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA-binding proteins. Involved in elongation. [...]
pas4 protein networkhttps://string-db.org/network/284812.Q9UUF0Peroxisome biogenesis factor 10; Somewhat implicated in the biogenesis of peroxisomes. Belongs to the pex2/pex10/pex12 family.
SPBC17A3.08 protein networkhttps://string-db.org/network/284812.Q9UUF1Deoxyribonuclease Tat-D; Has both endo- and exonuclease activities. Incises double- stranded DNA without obvious specificity via its endonuclease activity and excises the DNA from the 3'-to 5'-en [...]
rar1 protein networkhttps://string-db.org/network/284812.Q9UUF2Probable methionine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
SPBC17A3.03c protein networkhttps://string-db.org/network/284812.Q9UUF3Probable tyrosine-protein phosphatase C17A3.03c; Belongs to the protein-tyrosine phosphatase family.
aim19 protein networkhttps://string-db.org/network/284812.Q9UUF4Altered inheritance of mitochondria protein 19 homolog.
sec26 protein networkhttps://string-db.org/network/284812.Q9UUF7Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynth [...]
fas1 protein networkhttps://string-db.org/network/284812.Q9UUG03-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains [...]
rpf2 protein networkhttps://string-db.org/network/284812.Q9UUG1Ribosome production factor 2 homolog.
SPAC926.06c protein networkhttps://string-db.org/network/284812.Q9UUG2Uncharacterized leucine-rich repeat-containing protein C926.06c.
dph4 protein networkhttps://string-db.org/network/284812.Q9UUG3Diphthamide biosynthesis protein 4; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthami [...]
rlc1 protein networkhttps://string-db.org/network/284812.Q9UUG5Myosin regulatory light chain 1.
SPAC926.02 protein networkhttps://string-db.org/network/284812.Q9UUG6UPF0656 protein C926.02.
tup12 protein networkhttps://string-db.org/network/284812.Q9UUG8Transcriptional repressor tup12; Transcriptional repressor.
tsc2 protein networkhttps://string-db.org/network/284812.Q9UUG9Tuberous sclerosis 2 protein homolog; Together with tsc1, required for uptake of various amino acids from the environment and for proper conjugation. Involved in induction of gene expression of p [...]
SPAC630.12 protein networkhttps://string-db.org/network/284812.Q9UUH0Uncharacterized protein C630.12.
vps55 protein networkhttps://string-db.org/network/284812.Q9UUH1Vacuolar protein sorting-associated protein 55; Involved in protein transport from endosomes to the vacuole. Belongs to the OB-RGRP/VPS55 family.
bmt2 protein networkhttps://string-db.org/network/284812.Q9UUH225S rRNA adenine-N(1) methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA; Belongs [...]
mug58 protein networkhttps://string-db.org/network/284812.Q9UUH3Uncharacterized kinase mug58; Has a role in meiosis; Belongs to the GLYK kinase family.
erg25 protein networkhttps://string-db.org/network/284812.Q9UUH4Methylsterol monooxygenase; Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol; Belongs to the sterol desaturase family.
SPAC630.07c protein networkhttps://string-db.org/network/284812.Q9UUH5Uncharacterized protein C630.07c.
SPAC630.06c protein networkhttps://string-db.org/network/284812.Q9UUH6Uncharacterized nucleolar protein C630.06c.
gyp7 protein networkhttps://string-db.org/network/284812.Q9UUH7GTPase-activating protein gyp7; Most effectively accelerates the intrinsic GTPase activity of ypt7.
lsm6 protein networkhttps://string-db.org/network/284812.Q9UUI1U6 snRNA-associated Sm-like protein LSm6; Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient associat [...]
shf1 protein networkhttps://string-db.org/network/284812.Q9UUI2Small histone ubiquitination factor 1; Component of the histone H2B ubiquitin ligase complex (HULC) which plays a role in transcription regulation by catalyzing the monoubiquitination of histone [...]
sap145 protein networkhttps://string-db.org/network/284812.Q9UUI3Pre-mRNA-splicing factor sap145; Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures [...]
rrp16 protein networkhttps://string-db.org/network/284812.Q9UUI4Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.
sec24 protein networkhttps://string-db.org/network/284812.Q9UUI5Protein transport protein sec24; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main fun [...]
rtf1 protein networkhttps://string-db.org/network/284812.Q9UUI6Replication termination factor 1; Mediates site-specific replication termination at the polar replication barrier RTS1, a barrier which ensures that replication of the mat1 locus in S.pombe occur [...]
SPAC22F8.05 protein networkhttps://string-db.org/network/284812.Q9UUI7Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 100 kDa subunit.
pet1 protein networkhttps://string-db.org/network/284812.Q9UUI8Uncharacterized transporter C22F8.04.
pvg5 protein networkhttps://string-db.org/network/284812.Q9UUJ0Pyruvylated Gal-beta-1,3-epitope synthesis protein 5; Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moeities to galactomannans and their subsequent pyruvylation. Has [...]
arp2 protein networkhttps://string-db.org/network/284812.Q9UUJ1Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting fact [...]
rga9 protein networkhttps://string-db.org/network/284812.Q9UUJ3Probable Rho-GTPase-activating protein 9.
rec24 protein networkhttps://string-db.org/network/284812.Q9UUJ4Meiotic recombination protein rec24; Required for correct meiotic chromosome segregation and recombination.
mrpl25 protein networkhttps://string-db.org/network/284812.Q9UUJ554S ribosomal protein L25, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL59 family.
ned1 protein networkhttps://string-db.org/network/284812.Q9UUJ6Nuclear elongation and deformation protein 1; May have a role in the maintenance of the nuclear envelope structure and in minichromosome stability. Belongs to the lipin family.
csn71 protein networkhttps://string-db.org/network/284812.Q9UUJ7COP9 signalosome complex subunit 7; Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cull [...]
ach1 protein networkhttps://string-db.org/network/284812.Q9UUJ9Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.
SPAC1952.08c protein networkhttps://string-db.org/network/284812.Q9UUK0Pyridoxamine 5'-phosphate oxidase C1952.08c homolog; Belongs to the pyridoxamine 5'-phosphate oxidase family.
SPAC1952.06c protein networkhttps://string-db.org/network/284812.Q9UUK1Beta-catenin-like protein 1 homolog; Probable spliceosomal component involved in the activation of pre-mRNA splicing.
gcn5 protein networkhttps://string-db.org/network/284812.Q9UUK2Histone acetyltransferase gcn5; Acetylates histone H2B to form H2BK11ac and H2BK16ac, histone H3 to form H3K14ac, and with a lower preference histone H4 to form H4K8ac and H4K16ac. Acetylation of [...]
otu2 protein networkhttps://string-db.org/network/284812.Q9UUK3Ubiquitin thioesterase otu2; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degrad [...]
tma23 protein networkhttps://string-db.org/network/284812.Q9UUK4Uncharacterized protein C1952.02.
ade5 protein networkhttps://string-db.org/network/284812.Q9UUK7Phosphoribosylglycinamide formyltransferase; Belongs to the GART family.
rad57 protein networkhttps://string-db.org/network/284812.Q9UUL2DNA repair protein rhp57; Involved in recombination DNA repair and in the repair of gamma-ray-induced damage.
mok12 protein networkhttps://string-db.org/network/284812.Q9UUL4Cell wall alpha-1,3-glucan synthase mok12.
swi1 protein networkhttps://string-db.org/network/284812.Q9UUM2Mating-type switching protein swi1; Forms a fork protection complex (FPC) with swi3. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. It is required for p [...]
hob3 protein networkhttps://string-db.org/network/284812.Q9UUM7Protein hob3; Involved in cytokinesis and septation where it has a role in the localization of F-actin.
SPCC297.06c protein networkhttps://string-db.org/network/284812.Q9UUN3Uncharacterized protein C297.06c.
yip3 protein networkhttps://string-db.org/network/284812.Q9UUN5PRA1-like protein.
SPAC8E11.10 protein networkhttps://string-db.org/network/284812.Q9Y6Z9Sorbose reductase sou1; Catalyzes the NADP dependent reduction of L-sorbose to D- glucitol; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
tuf1 protein networkhttps://string-db.org/network/284812.Q9Y700Elongation factor Tu, mitochondrial; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class transla [...]
alp31 protein networkhttps://string-db.org/network/284812.Q9Y703Tubulin-specific chaperone A; Required for the maintenance of microtubule structures and cell polarity. Beta-tubulin-folding protein; may have a regulatory role in the tubulin-folding pathway.
mok14 protein networkhttps://string-db.org/network/284812.Q9Y704Cell wall alpha-1,3-glucan synthase mok14.
alp4 protein networkhttps://string-db.org/network/284812.Q9Y705Spindle pole body component alp4; Component of the gamma tubule complex that is required for the regulation of both interphase microtubules and mitotic bipolar spindles. Required for correct sept [...]
skp1 protein networkhttps://string-db.org/network/284812.Q9Y709Suppressor of kinetochore protein 1; Required for cig2 degradation in the G2 and M phases of the cell cycle. Together with pof6, essential for septum processing and cell separation. Involved in m [...]
mok13 protein networkhttps://string-db.org/network/284812.Q9Y719Cell wall alpha-1,3-glucan synthase mok13.
mis12 protein networkhttps://string-db.org/network/284812.Q9Y738Centromere protein mis12; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycl [...]
orc4 protein networkhttps://string-db.org/network/284812.Q9Y794Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcript [...]
alg3 protein networkhttps://string-db.org/network/284812.Q9Y7I4Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol; Belongs to the glycosyltransferase 58 f [...]
zuo1 protein networkhttps://string-db.org/network/284812.Q9Y7I8Zuotin; Component of the ribosome-associated complex (RAC), a heterodimeric chaperone complex involved in regulation of accurate translation termination and in folding or maintaining nascent poly [...]
SPBC1778.03c protein networkhttps://string-db.org/network/284812.Q9Y7J0Probable NADH pyrophosphatase; Belongs to the Nudix hydrolase family. NudC subfamily.
spo6 protein networkhttps://string-db.org/network/284812.Q9Y7J1Sporulation-specific protein 6; May act as a kinase regulator. Essential for progression of meiosis II and sporulation.
lam2 protein networkhttps://string-db.org/network/284812.Q9Y7J2Uncharacterized protein C1778.05c.
SPBC1778.07 protein networkhttps://string-db.org/network/284812.Q9Y7J3Carnosine N-methyltransferase; N-methyltransferase that mediates the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Also methylates other L-histidine-containing di- [...]
arc3 protein networkhttps://string-db.org/network/284812.Q9Y7J4Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promot [...]
pdk1 protein networkhttps://string-db.org/network/284812.Q9Y7J6Serine/threonine-protein kinase ppk21; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.
psy2 protein networkhttps://string-db.org/network/284812.Q9Y7J8Uncharacterized protein C216.01c.
num1 protein networkhttps://string-db.org/network/284812.Q9Y7J9Meiotic coiled-coil protein 5; Involved in chromosome segregation. Facilitates nuclear oscillation during meiotic prophase I, the 'horsetail' phase, by acting as a dynein anchor. Essential for an [...]
SPBC216.03 protein networkhttps://string-db.org/network/284812.Q9Y7K0UPF0659 protein C216.03.
mxr2 protein networkhttps://string-db.org/network/284812.Q9Y7K1Uncharacterized protein C216.04c; Belongs to the MsrB Met sulfoxide reductase family.
tor2 protein networkhttps://string-db.org/network/284812.Q9Y7K2Serine/threonine-protein kinase tor2; Phosphatidylinositol 3-kinase homolog, component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental si [...]
SPBC2A9.02 protein networkhttps://string-db.org/network/284812.Q9Y7K4Uncharacterized protein C2A9.02; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
SPBC2A9.03 protein networkhttps://string-db.org/network/284812.Q9Y7K5Uncharacterized WD repeat-containing protein C2A9.03.
san1 protein networkhttps://string-db.org/network/284812.Q9Y7K6Uncharacterized RING finger protein C2A9.04c.
tvp23 protein networkhttps://string-db.org/network/284812.Q9Y7K7Golgi apparatus membrane protein tvp23; Golgi membrane protein involved in vesicular trafficking. Belongs to the TVP23 family.
nus1 protein networkhttps://string-db.org/network/284812.Q9Y7K8Dehydrodolichyl diphosphate synthase complex subunit nus1; With SPAC4D7.04c, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Do [...]
hpz1 protein networkhttps://string-db.org/network/284812.Q9Y7K9PARP-type zinc finger-containing protein C2A9.07c.
sec22 protein networkhttps://string-db.org/network/284812.Q9Y7L0Protein transport protein sec22; Nonessential SNARE involved in targeting and fusion of ER- derived transport vesicles with the Golgi complex as well as Golgi- derived retrograde transport vesicl [...]
plp2 protein networkhttps://string-db.org/network/284812.Q9Y7L1Phosducin-like protein C2A9.09; Belongs to the phosducin family.
bmc1 protein networkhttps://string-db.org/network/284812.Q9Y7L2Probable RNA methyltransferase C2A9.10; Probable RNA methyltransferase.
exo5 protein networkhttps://string-db.org/network/284812.Q9Y7L4Probable exonuclease V, mitochondrial; Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination. Releases dinucleotides as main products of catalysis. [...]
aps2 protein networkhttps://string-db.org/network/284812.Q9Y7L6AP-2 complex subunit sigma; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytopla [...]
gpi15 protein networkhttps://string-db.org/network/284812.Q9Y7L7Phosphatidylinositol N-acetylglucosaminyltransferase subunit gpi15; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the f [...]
rps001 protein networkhttps://string-db.org/network/284812.Q9Y7L840S ribosomal protein S0-A; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of th [...]
SPBC685.08 protein networkhttps://string-db.org/network/284812.Q9Y7L9Uncharacterized protein C685.08.
hac1 protein networkhttps://string-db.org/network/284812.Q9Y7M1Putative 2-hydroxyacyl-CoA lyase; Catalyzes a carbon-carbon cleavage reaction; cleaves a 2- hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde; Belongs to the TPP enz [...]
pib2 protein networkhttps://string-db.org/network/284812.Q9Y7M3FYVE-type zinc finger-containing protein C9B6.03.
lsm3 protein networkhttps://string-db.org/network/284812.Q9Y7M4Probable U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
mrpl10 protein networkhttps://string-db.org/network/284812.Q9Y7M554S ribosomal protein L10, mitochondrial; Belongs to the universal ribosomal protein uL15 family.
nop52 protein networkhttps://string-db.org/network/284812.Q9Y7M6Ribosomal RNA-processing protein 1 homolog; Required for 27S rRNA processing to 25S and 5.8S. Belongs to the RRP1 family.
mdl1 protein networkhttps://string-db.org/network/284812.Q9Y7M7ATP-dependent permease MDL1, mitochondrial; Mediates export of peptides generated upon proteolysis of mitochondrial inner membrane proteins; Belongs to the ABC transporter superfamily. ABCB famil [...]
SPBC9B6.11c protein networkhttps://string-db.org/network/284812.Q9Y7M8Probable RNA exonuclease C9B6.11c.
bdf1 protein networkhttps://string-db.org/network/284812.Q9Y7N0SWR1 complex bromodomain subunit bdf1; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of se [...]
utp502 protein networkhttps://string-db.org/network/284812.Q9Y7N1Uncharacterized protein C1450.03.
rox3 protein networkhttps://string-db.org/network/284812.Q9Y7N2Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
grx3 protein networkhttps://string-db.org/network/284812.Q9Y7N3Monothiol glutaredoxin-3; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters (By similarity). Binds one iron-sulfur cluster per dimer. The iron-sulfur cluster is bound bet [...]
dao1 protein networkhttps://string-db.org/network/284812.Q9Y7N4D-amino-acid oxidase; Belongs to the DAMOX/DASOX family.
wtf16 protein networkhttps://string-db.org/network/284812.Q9Y7N5Uncharacterized protein wtf16.
plb5 protein networkhttps://string-db.org/network/284812.Q9Y7N6Putative lysophospholipase C1450.09c; Catalyzes the release of fatty acids from lysophospholipids.
nar1 protein networkhttps://string-db.org/network/284812.Q9Y7N7Cytosolic Fe-S cluster assembly factor NAR1 homolog; Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in th [...]
SPCC1450.12 protein networkhttps://string-db.org/network/284812.Q9Y7N9PX domain-containing protein C1450.12.
rib5 protein networkhttps://string-db.org/network/284812.Q9Y7P0Riboflavin synthase; Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil.
ero12 protein networkhttps://string-db.org/network/284812.Q9Y7P1ERO1-like protein 2; Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly pdi1 isomerase through a direct disulfide [...]
SPCC1450.15 protein networkhttps://string-db.org/network/284812.Q9Y7P2Uncharacterized protein C1450.15; Acts in the GPI biosynthetic pathway between GlcNAc-PI synthesis and GPI transfer to protein. Required for the formation of complete GPI precursors CP1 and CP2 ( [...]
ptl1 protein networkhttps://string-db.org/network/284812.Q9Y7P3Probable triacylglycerol lipase C1450.16c; Releases specific fatty acids from neutral lipid triacylglycerols (TAG) thereby supplying fatty acids to a general acylation process.
rml2 protein networkhttps://string-db.org/network/284812.Q9Y7P454S ribosomal protein rml2, mitochondrial; Belongs to the universal ribosomal protein uL2 family.
mug72 protein networkhttps://string-db.org/network/284812.Q9Y7P6Meiotically up-regulated gene 72 protein; Has a role in meiosis.
SPCC191.05c protein networkhttps://string-db.org/network/284812.Q9Y7P9Uncharacterized protein C191.05c.
lto1 protein networkhttps://string-db.org/network/284812.Q9Y7Q1LTO1 family protein C191.08; The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery [...]
gst1 protein networkhttps://string-db.org/network/284812.Q9Y7Q2Glutathione S-transferase 1; Involved in the oxidative stress response and detoxification.
SPCC191.10 protein networkhttps://string-db.org/network/284812.Q9Y7Q3Uncharacterized protein C191.10.
set7 protein networkhttps://string-db.org/network/284812.Q9Y7Q6SET domain-containing protein 7; Belongs to the class V-like SAM-binding methyltransferase superfamily.
SPCC297.05 protein networkhttps://string-db.org/network/284812.Q9Y7Q7DENN domain-containing protein C297.05.
pho843 protein networkhttps://string-db.org/network/284812.Q9Y7Q9Probable metabolite transporter C2H8.02.
cnd2 protein networkhttps://string-db.org/network/284812.Q9Y7R3Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex p [...]
set1 protein networkhttps://string-db.org/network/284812.Q9Y7R4Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the Set1 complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. Methylation promot [...]
ins1 protein networkhttps://string-db.org/network/284812.Q9Y7R5INSIG family protein.
big1 protein networkhttps://string-db.org/network/284812.Q9Y7R6Protein big1; Required for normal beta-1,6-glucan synthesis; Belongs to the BIG1 family.
SPCC306.07c protein networkhttps://string-db.org/network/284812.Q9Y7R7Putative ribosome biogenesis protein C306.07c; Involved in rRNA-processing and ribosome biosynthesis.
mdh1 protein networkhttps://string-db.org/network/284812.Q9Y7R8Malate dehydrogenase, mitochondrial.
SPCC306.11 protein networkhttps://string-db.org/network/284812.Q9Y7R9Uncharacterized protein C306.11.
SPCC569.01c protein networkhttps://string-db.org/network/284812.Q9Y7S0UPF0612 protein C569.01c; Belongs to the UPF0612 family.
SPCC569.02c protein networkhttps://string-db.org/network/284812.Q9Y7S1UPF0321 protein C569.02c; Belongs to the UPF0321 family.
SPCC569.03 protein networkhttps://string-db.org/network/284812.Q9Y7S2UPF0612 protein C569.003.
SPCC569.05c protein networkhttps://string-db.org/network/284812.Q9Y7S4Uncharacterized transporter C569.05c.
SPCC569.06 protein networkhttps://string-db.org/network/284812.Q9Y7S5Uncharacterized membrane protein C569.06.
SPCC569.07 protein networkhttps://string-db.org/network/284812.Q9Y7S6Aromatic amino acid aminotransferase C569.07; Has aromatic amino acid transaminase activity. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
dbl1 protein networkhttps://string-db.org/network/284812.Q9Y7S8Uncharacterized protein C2H8.05c.
aah3 protein networkhttps://string-db.org/network/284812.Q9Y7S9Alpha-amylase 3; Has a role in cell wall biosynthesis where it is involved in maintaining cell wall strength and shape.
SPCC63.03 protein networkhttps://string-db.org/network/284812.Q9Y7T0Uncharacterized J domain-containing protein C63.03.
tap42 protein networkhttps://string-db.org/network/284812.Q9Y7T1Uncharacterized protein C63.05; Belongs to the IGBP1/TAP42 family.
SPCC63.06 protein networkhttps://string-db.org/network/284812.Q9Y7T2Uncharacterized WD repeat-containing protein C63.06.
thg1 protein networkhttps://string-db.org/network/284812.Q9Y7T3tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
atg1 protein networkhttps://string-db.org/network/284812.Q9Y7T4Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the for [...]
sec59 protein networkhttps://string-db.org/network/284812.Q9Y7T6Dolichol kinase sec59; Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors. It is requi [...]
prp28 protein networkhttps://string-db.org/network/284812.Q9Y7T7Pre-mRNA-splicing ATP-dependent RNA helicase prp28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5 [...]
pup3 protein networkhttps://string-db.org/network/284812.Q9Y7T8Probable proteasome subunit beta type-3; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent t [...]
SPCC63.13 protein networkhttps://string-db.org/network/284812.Q9Y7T9Uncharacterized J domain-containing protein C63.13.
eis1 protein networkhttps://string-db.org/network/284812.Q9Y7U0Uncharacterized protein C63.14.
sfk1 protein networkhttps://string-db.org/network/284812.Q9Y7U1Protein sfk1; May control the production of phosphatidylinositol 4- phosphate (PI4P); Belongs to the SFK1 family.
gep4 protein networkhttps://string-db.org/network/284812.Q9Y7U3Probable phosphatidylglycerophosphatase, mitochondrial; Phosphatidylglycerophosphatase involved in the biosynthesis of cardiolipin (CL), a unique dimeric phosphoglycerolipid predominantly present [...]
nse3 protein networkhttps://string-db.org/network/284812.Q9Y7U4Non-structural maintenance of chromosome element 3; Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of i [...]
rgf3 protein networkhttps://string-db.org/network/284812.Q9Y7U5Rho1 guanine nucleotide exchange factor 3; Stimulates the exchange of Rho1 GDP-bound form into GTP-bound form. Regulates, via interaction and activation of Rho1, beta-1,3- glucan biosynthesis and [...]
rgf1 protein networkhttps://string-db.org/network/284812.Q9Y7U6Rho1 guanine nucleotide exchange factor 1; Stimulates the exchange of Rho1 and Rho5 GDP-bound form into GTP-bound form. Controls septum formation, cell wall synthesis and localization of F-actin [...]
snd1 protein networkhttps://string-db.org/network/284812.Q9Y7U7Staphylococcal nuclease domain-containing protein 1.
mrpl37 protein networkhttps://string-db.org/network/284812.Q9Y7U854S ribosomal protein L37, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL54 family.
cca2 protein networkhttps://string-db.org/network/284812.Q9Y7U9tRNA nucleotidyltransferase cca2; tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus. In contrast to what is usually observed in eukaryotes for which one enzyme synthe [...]
bye1 protein networkhttps://string-db.org/network/284812.Q9Y7V2Transcription factor bye1; Negative regulator of transcription elongation. Belongs to the BYE1 family.
nat1 protein networkhttps://string-db.org/network/284812.Q9Y7X2N-terminal acetyltransferase A complex subunit-like protein C418.02; Non-catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-S [...]
SPBC365.16 protein networkhttps://string-db.org/network/284812.Q9Y7X4Uncharacterized membrane protein C365.16.
uge1 protein networkhttps://string-db.org/network/284812.Q9Y7X5UDP-glucose 4-epimerase uge1; Major UDP-glucose/-galactose 4-epimerase under glucose-rich conditions involved in protein galactosylation.
ish1 protein networkhttps://string-db.org/network/284812.Q9Y7X6Stress response protein ish1; Has a role in maintaining cell viability during stationary phase induced by stress response. Activated by the spc1 MAPK pathway. Belongs to the LEA type 1 family.
grp2 protein networkhttps://string-db.org/network/284812.Q9Y7X7GRIP and coiled-coil domain-containing protein C365.11.
arp5 protein networkhttps://string-db.org/network/284812.Q9Y7X8Actin-like protein arp5; Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
kin17 protein networkhttps://string-db.org/network/284812.Q9Y7X9KIN17-like protein.
der1 protein networkhttps://string-db.org/network/284812.Q9Y7Y0Uncharacterized derlin-like protein C365.08c.
tmf1 protein networkhttps://string-db.org/network/284812.Q9Y7Y1Protein sgm1.
slu7 protein networkhttps://string-db.org/network/284812.Q9Y7Y2Pre-mRNA-splicing factor slu7; Involved in pre-mRNA splicing.
SPBC365.04c protein networkhttps://string-db.org/network/284812.Q9Y7Y3Uncharacterized RNA-binding protein C365.04c.
cox10 protein networkhttps://string-db.org/network/284812.Q9Y7Y4Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O.
rtt109 protein networkhttps://string-db.org/network/284812.Q9Y7Y5Histone acetyltransferase rtt109; Required for acetylation of 'Lys-56' of histone H3 (H3K56ac), which occurs predominantly in newly synthesized H3 molecule during G1, S-phase and G2/M of cell cyc [...]
rpn1301 protein networkhttps://string-db.org/network/284812.Q9Y7Y6Uncharacterized protein C342.04.
gas4 protein networkhttps://string-db.org/network/284812.Q9Y7Y71,3-beta-glucanosyltransferase gas4; Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan mol [...]
qrs1 protein networkhttps://string-db.org/network/284812.Q9Y7Y8Probable glutamine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
nop16 protein networkhttps://string-db.org/network/284812.Q9Y7Z1Nucleolar protein 16; Involved in the biogenesis of the 60S ribosomal subunit.
arf6 protein networkhttps://string-db.org/network/284812.Q9Y7Z2ADP-ribosylation factor 6; GTP-binding protein that functions as a molecular switch for the activation of 'new end take off' (NETO), a process in which the directions of cell growth change from a [...]
acb1 protein networkhttps://string-db.org/network/284812.Q9Y7Z3Putative acyl-CoA-binding protein; Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters; Belongs to the ACBP family [...]
cog3 protein networkhttps://string-db.org/network/284812.Q9Y7Z4Conserved oligomeric Golgi complex subunit 3; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis- Golgi, and r [...]
tts1 protein networkhttps://string-db.org/network/284812.Q9Y7Z5Tetra-spanning protein 1; Required for the correct positioning of the cellular division plane by delimiting the actomyosin ring assembly at the cell equator.
SPBC1539.02 protein networkhttps://string-db.org/network/284812.Q9Y7Z6Meiotic chromosome segregation protein C1539.02; Required for meiotic chromosome segregation.
mrp15 protein networkhttps://string-db.org/network/284812.Q9Y7Z754S ribosomal protein L15, mitochondrial; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL57 subfamily.
myo1 protein networkhttps://string-db.org/network/284812.Q9Y7Z8Myosin-1; Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures toget [...]
coq6 protein networkhttps://string-db.org/network/284812.Q9Y7Z9Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-poly [...]
mug57 protein networkhttps://string-db.org/network/284812.Q9Y801FAS1 domain-containing protein mug57; Has a role in sporulation.
lsd1 protein networkhttps://string-db.org/network/284812.Q9Y802Lysine-specific histone demethylase 1; Catalytic component of the SWM histone demethylase complex that specifically demethylates H3K9me2, a specific tag for epigenetic transcriptional activation, [...]
tif1102 protein networkhttps://string-db.org/network/284812.Q9Y803S1-like domain-containing protein C146.08c.
fan1 protein networkhttps://string-db.org/network/284812.Q9Y804Fanconi-associated nuclease 1 homolog; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA success [...]
cwf25 protein networkhttps://string-db.org/network/284812.Q9Y805Pre-mRNA-splicing factor cwf25; Involved in mRNA splicing.
erv2 protein networkhttps://string-db.org/network/284812.Q9Y806FAD-linked sulfhydryl oxidase erv2; FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation in the endoplasmic reticulum lumen.
med15 protein networkhttps://string-db.org/network/284812.Q9Y808Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
naa25 protein networkhttps://string-db.org/network/284812.Q9Y809N-terminal acetyltransferase B complex subunit arm1; Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all p [...]
shy1 protein networkhttps://string-db.org/network/284812.Q9Y810Cytochrome oxidase assembly protein shy1; Required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane; Belongs to the SURF1 family.
pth3 protein networkhttps://string-db.org/network/284812.Q9Y811Uncharacterized peptide chain release factor-like protein C1105.18c, mitochondrial.
cnp1 protein networkhttps://string-db.org/network/284812.Q9Y812Histone H3-like centromeric protein cnp1; Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. [...]
rpr2 protein networkhttps://string-db.org/network/284812.Q9Y813Ribonuclease P protein subunit rpr2; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P prot [...]
htd2 protein networkhttps://string-db.org/network/284812.Q9Y814Hydroxyacyl-thioester dehydratase type 2, mitochondrial; Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis. Required for respiratory growth and for normal mito [...]
rsv2 protein networkhttps://string-db.org/network/284812.Q9Y815Zinc finger protein rsv2.
rav1 protein networkhttps://string-db.org/network/284812.Q9Y817Regulator of V-ATPase in vacuolar membrane protein 1; Component of the RAVE complex which is required for stable assembly of the vacuolar ATPase complex V-ATPase.
ubc15 protein networkhttps://string-db.org/network/284812.Q9Y818Ubiquitin-conjugating enzyme E2 15; Catalyzes the covalent attachment of ubiquitin to other proteins. Has a role in the formation of chromatin structures that influence the localization of transc [...]
emp70 protein networkhttps://string-db.org/network/284812.Q9Y819Transmembrane 9 superfamily protein C1105.08.
pci2 protein networkhttps://string-db.org/network/284812.Q9Y820PCI domain-containing protein C1105.07c.
pmc4 protein networkhttps://string-db.org/network/284812.Q9Y821Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Me [...]
mrpl16 protein networkhttps://string-db.org/network/284812.Q9Y82254S ribosomal protein L16, mitochondrial.
lys4 protein networkhttps://string-db.org/network/284812.Q9Y823Homocitrate synthase, mitochondrial; Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysin [...]
SPBC1105.01 protein networkhttps://string-db.org/network/284812.Q9Y824Uncharacterized protein C1105.01.
pcf3 protein networkhttps://string-db.org/network/284812.Q9Y825Uncharacterized WD repeat-containing protein C25H1.06.
meu31 protein networkhttps://string-db.org/network/284812.Q9Y826Meiotic expression up-regulated protein 31.
ptl3 protein networkhttps://string-db.org/network/284812.Q9Y827Uncharacterized protein C1A6.05c.
psh3 protein networkhttps://string-db.org/network/284812.Q9Y876Secretory component protein psh3; Involved in amino acid permease processing and required for the efficient translocation of structurally related amino acid permeases from the endoplasmic reticul [...]
pek1 protein networkhttps://string-db.org/network/284812.Q9Y884MAP kinase kinase skh1/pek1; Involved in the mkh1 signal transduction pathway that plays a role in cell wall integrity. Activates spm1/pmk1 via phosphorylation.
mex67 protein networkhttps://string-db.org/network/284812.Q9Y8G3mRNA export factor mex67; Involved in the export of mRNA from the nucleus to the cytoplasm; Belongs to the NXF family.
sos7 protein networkhttps://string-db.org/network/284812.U3H042Kinetochore protein Sos7; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycl [...]
SPCC1884.01 protein networkhttps://string-db.org/network/284812.U3H0A9Uncharacterized protein SPCC1884.01.
wtf25 protein networkhttps://string-db.org/network/284812.U3H0P2Uncharacterized protein wtf25.