Organism Overview: Nanoarchaeum equitans


 
NEQ001 protein networkhttps://string-db.org/network/228908.NEQ001NEQ001; Conserved hypothetical [Methanococcus jannaschii]; COG1583:Uncharacterized ACR; IPR001472:Bipartite nuclear localization signal; IPR002743: Protein of unknown function DUF57.
NEQ002 protein networkhttps://string-db.org/network/228908.NEQ002NEQ002; FKBP-type peptidyl-prolyl cis-trans isomerase; COG1047:FKBP-type peptidyl-prolyl cis-trans isomerases 2; IPR000931:Adenovirus fibre protein.
NEQ003 protein networkhttps://string-db.org/network/228908.NEQ003NEQ003; Large helicase-related protein [Pyrococcus abyssi]. SPLIT See NEQ409; COG1201: Lhr-like helicases; IPR001410: DEAD/DEAH box helicase; IPR001472: Bipartite nuclear localization signal; IPR [...]
NEQ004 protein networkhttps://string-db.org/network/228908.NEQ004NEQ004; Conserved hypothetical protein [Methanococcus jannaschii]; COG1371: Uncharacterized ACR; IPR002804: Protein of unknown function DUF101; IPR001472: Bipartite nuclear localization signal.
NEQ005 protein networkhttps://string-db.org/network/228908.NEQ005NEQ005; tRNA m(1)G methyltransferase; COG2419: Uncharacterized ACR.
NEQ006 protein networkhttps://string-db.org/network/228908.NEQ006NEQ006.
NEQ007 protein networkhttps://string-db.org/network/228908.NEQ007NEQ007; Cysteine methyltransferase [Pyrobaculum aeruphilum]; COG0350: Methylated DNA-protein cysteine methyltransferase; IPR001497: Methylated-DNA-protein-cysteine methyltransferase.
NEQ008 protein networkhttps://string-db.org/network/228908.NEQ008NEQ008; Hypothetical protein, contains Radical Sam domain; COG0621: 2-methylthioadenine synthetase; IPR001861: Uncharacterized protein family UPF0004.
NEQ009 protein networkhttps://string-db.org/network/228908.NEQ009NEQ009; Conserved hypothetical protein [Pyrobaculum aerophilum].
NEQ010 protein networkhttps://string-db.org/network/228908.NEQ010NEQ010.
NEQ011 protein networkhttps://string-db.org/network/228908.NEQ011NEQ011; Desulfoferrodoxin [Pyrococcus horikoshii]; COG2033: Desulfoferrodoxin; IPR002742: Desulfoferrodoxin.
NEQ012 protein networkhttps://string-db.org/network/228908.NEQ012NEQ012; Glycosyltransferase [Mehanosarcina acetivorans]; COG0438: Predicted glycosyltransferases; IPR001296: Glycosyl transferases group 1.
NEQ013 protein networkhttps://string-db.org/network/228908.NEQ013NEQ013; Hypothetical protein, contains Radical Sam domain; COG0535: Predicted Fe-S oxidoreductases; IPR000385: MoaA / nifB / pqqE family.
NEQ014 protein networkhttps://string-db.org/network/228908.NEQ014NEQ014; C4-dicarboxylate transporter [Magnetococcus sp]; COG1275: Tellurite resistance protein and related permeases.
NEQ015 protein networkhttps://string-db.org/network/228908.NEQ015NEQ015; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the m [...]
cas2 protein networkhttps://string-db.org/network/228908.NEQ016NEQ016; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements an [...]
cas1 protein networkhttps://string-db.org/network/228908.NEQ017NEQ017; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements an [...]
NEQ018 protein networkhttps://string-db.org/network/228908.NEQ018NEQ018.
NEQ019 protein networkhttps://string-db.org/network/228908.NEQ019NEQ019; Conserved hypothetical protein [Pyrococcus horikoshii]; COG1857: Uncharacterized ACR.
NEQ020 protein networkhttps://string-db.org/network/228908.NEQ020NEQ020.
NEQ021 protein networkhttps://string-db.org/network/228908.NEQ021NEQ021; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and [...]
NEQ022 protein networkhttps://string-db.org/network/228908.NEQ022NEQ022; DEAD Box helicase; COG1203: Predicted helicases; IPR001410: DEAD/DEAH box helicase; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR001472: Bipartite nuclear localization signal; IPR [...]
NEQ023 protein networkhttps://string-db.org/network/228908.NEQ023NEQ023; Peptidase M16 [Pyrobaculum aerophilum]; COG0612: Predicted Zn-dependent peptidases.
NEQ024 protein networkhttps://string-db.org/network/228908.NEQ024NEQ024; Pyridine nucleotide-disulphide oxidoreductase; COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases; IPR001327: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
NEQ025 protein networkhttps://string-db.org/network/228908.NEQ025NEQ025; Glucose-1-phosphate uridyltransferase [Archaeoglobus fulgidus]; COG1208: Nucleoside-diphosphate-sugar pyrophosphorylases involved in lipopolysaccharide biosynthesis-translation initiation [...]
NEQ026 protein networkhttps://string-db.org/network/228908.NEQ026NEQ026.
NEQ027 protein networkhttps://string-db.org/network/228908.NEQ027NEQ027.
NEQ028 protein networkhttps://string-db.org/network/228908.NEQ028NEQ028.
NEQ029 protein networkhttps://string-db.org/network/228908.NEQ029NEQ029.
NEQ030 protein networkhttps://string-db.org/network/228908.NEQ030NEQ030; Conserved hypothetical protein; IPR003834: Cytochrome c biogenesis protein transmembrane region.
NEQ031 protein networkhttps://string-db.org/network/228908.NEQ031NEQ031; Predicted RNA binding protein; COG1094: Predicted RNA-binding protein (contains KH domains); IPR001472: Bipartite nuclear localization signal.
NEQ032 protein networkhttps://string-db.org/network/228908.NEQ032NEQ032.
NEQ033 protein networkhttps://string-db.org/network/228908.NEQ033NEQ033; Hypothetical protein [Cytophaga hutchinsonii].
NEQ034 protein networkhttps://string-db.org/network/228908.NEQ034NEQ034; Hypothetical protein; IPR000531: TonB-dependent receptor protein; PS50321: ASN_RICH.
NEQ035 protein networkhttps://string-db.org/network/228908.NEQ035NEQ035.
NEQ036 protein networkhttps://string-db.org/network/228908.NEQ036NEQ036.
NEQ037 protein networkhttps://string-db.org/network/228908.NEQ037NEQ037; Putative U6 small nuclear ribonucleoprotein; COG1958: Small nuclear ribonucleoprotein (snRNP) homolog; IPR001163: Small nuclear ribonucleoprotein (Sm protein).
rpl37ae protein networkhttps://string-db.org/network/228908.NEQ038NEQ038; Binds to the 23S rRNA.
NEQ039 protein networkhttps://string-db.org/network/228908.NEQ039NEQ039; Transcription initiation factor TFIID [Methanococcus jannaschii]; COG2101: Transcription initiation factor TFIID (TATA-binding protein); IPR000814: Transcription factor TFIID.
NEQ040 protein networkhttps://string-db.org/network/228908.NEQ040NEQ040; Hypothetical protein; IPR000326: PA-phosphatase related phosphoesterase.
NEQ041 protein networkhttps://string-db.org/network/228908.NEQ041NEQ041.
NEQ042 protein networkhttps://string-db.org/network/228908.NEQ042NEQ042; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.
NEQ043 protein networkhttps://string-db.org/network/228908.NEQ043NEQ043; Putative ribosomal protein.
NEQ044 protein networkhttps://string-db.org/network/228908.NEQ044NEQ044; O-sialoglycoprotein endopeptidase [Methanosarcina acetivorans]; COG3642: Mn2+-dependent serine/threonine protein kinase; IPR000719: Eukaryotic protein kinase; IPR001472: Bipartite nuclear [...]
NEQ045 protein networkhttps://string-db.org/network/228908.NEQ045NEQ045; DNA topoisomerase I [Pyrococcus horikoshii]; COG0550: Topoisomerase IA; IPR000380: Prokaryotic DNA topoisomerase I; IPR002936: Toprim domain; IPR003601: DNA topoisomerase I ATP-binding do [...]
NEQ046 protein networkhttps://string-db.org/network/228908.NEQ046NEQ046.
NEQ047 protein networkhttps://string-db.org/network/228908.NEQ047NEQ047; Putative molybdopterin biosynthesis protein [Aeropyrum pernix]; COG0476: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; IPR000594: UBA/THIF-t [...]
NEQ048 protein networkhttps://string-db.org/network/228908.NEQ048NEQ048.
NEQ049 protein networkhttps://string-db.org/network/228908.NEQ049NEQ049; Conserved hypothetical protein [Archaeglobus fulgidus]; COG1244: Predicted Fe-S oxidoreductases.
NEQ050 protein networkhttps://string-db.org/network/228908.NEQ050NEQ050; Hypothetical protein; COG1708: Predicted nucleotidyltransferases; COG1579: Zn-ribbon protein, possibly nucleic acid-binding.
NEQ051 protein networkhttps://string-db.org/network/228908.NEQ051NEQ051; Flavohemoprotein homolog; COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; IPR001433: Oxidoreductase FAD and NAD(P)-binding domain; IPR001709: Flavoprotein pyridine [...]
prf1 protein networkhttps://string-db.org/network/228908.NEQ052NEQ052; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
NEQ053 protein networkhttps://string-db.org/network/228908.NEQ053NEQ053; RNA methyltransferase TrmA; COG2265: SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; IPR000051: SAM (and some other nucleotide) binding motif; IPR001566: R [...]
NEQ054 protein networkhttps://string-db.org/network/228908.NEQ054NEQ054.
cysS protein networkhttps://string-db.org/network/228908.NEQ055NEQ055; cysteinyl-tRNA synthetase [Pyrococcus furiosus]; COG0215: Cysteinyl-tRNA synthetase; IPR002308: Cysteinyl-tRNA synthetase.
NEQ056 protein networkhttps://string-db.org/network/228908.NEQ056NEQ056.
NEQ057 protein networkhttps://string-db.org/network/228908.NEQ057NEQ057; Involved in regulation of DNA replication.
rps12 protein networkhttps://string-db.org/network/228908.NEQ058NEQ058; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
NEQ059 protein networkhttps://string-db.org/network/228908.NEQ059NEQ059; Twitching mobility related protein(PILT) [Pyrococcus abyssi]; COG1855: ATPases of the PilT family; IPR002716: PIN (PilT N terminus) domain; IPR000958: KH domain; IPR001687: ATP/GTP-bindin [...]
NEQ060 protein networkhttps://string-db.org/network/228908.NEQ060NEQ060.
NEQ061 protein networkhttps://string-db.org/network/228908.NEQ061NEQ061; Glycosyl transferase [Sulfolobus solfataricus]; COG0472: UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; IPR000715: Glycosyl transfer [...]
NEQ062 protein networkhttps://string-db.org/network/228908.NEQ062NEQ062; Conserved hypothetical protein; IPR001525: C-5 cytosine-specific DNA methylase.
rnhB protein networkhttps://string-db.org/network/228908.NEQ063NEQ063; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
rnz protein networkhttps://string-db.org/network/228908.NEQ064NEQ064; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the R [...]
rpl23 protein networkhttps://string-db.org/network/228908.NEQ065NEQ065; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
NEQ066 protein networkhttps://string-db.org/network/228908.NEQ066NEQ066.
NEQ067 protein networkhttps://string-db.org/network/228908.NEQ067NEQ067; Conserved protein [Methanosarcina mazei]; COG2248: Predicted hydrolase of the metallo-beta-lactamase superfamily; Belongs to the UPF0282 family.
NEQ068 protein networkhttps://string-db.org/network/228908.NEQ068NEQ068; DNA-directed DNA polymerase Family B [Pyrococcus furiosus] SPLIT see NEQ528; COG0417: DNA polymerase elongation subunit (family B); IPR002064: DNA-directed DNA polymerase family B.
rps11 protein networkhttps://string-db.org/network/228908.NEQ069NEQ069; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
NEQ070 protein networkhttps://string-db.org/network/228908.NEQ070NEQ070.
NEQ071 protein networkhttps://string-db.org/network/228908.NEQ071NEQ071; Conserved hypothetical protein [Archaeoglobus fulgidus].
NEQ072 protein networkhttps://string-db.org/network/228908.NEQ072NEQ072.
NEQ073 protein networkhttps://string-db.org/network/228908.NEQ073NEQ073.
NEQ074 protein networkhttps://string-db.org/network/228908.NEQ074NEQ074; Putative ABC heme transporter [Pyrococcus furiosus]; COG0396: Iron-regulated ABC transporter ATPase subunit SufC; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR003439: ABC transpor [...]
rpl18 protein networkhttps://string-db.org/network/228908.NEQ075NEQ075; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
NEQ076 protein networkhttps://string-db.org/network/228908.NEQ076NEQ076; Cleavage and polyadenylation specifity factor protein [Pyroc..; COG1782: Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain; IPR0012 [...]
NEQ077 protein networkhttps://string-db.org/network/228908.NEQ077NEQ077; Probable glutamate dehydrogenase [Thermoplasma volcanium]; COG0334: Glutamate dehydrogenase/leucine dehydrogenase; IPR001625: Glutamate/leucine/phenylalanine/valine dehydrogenase; Belongs [...]
NEQ077a protein networkhttps://string-db.org/network/228908.NEQ077aNEQ077a; Endonuclease IV [Pyrococcus furiosus].
rtcB protein networkhttps://string-db.org/network/228908.NEQ078NEQ078; GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends; Belongs to the RtcB fami [...]
NEQ079 protein networkhttps://string-db.org/network/228908.NEQ079NEQ079.
NEQ080 protein networkhttps://string-db.org/network/228908.NEQ080NEQ080.
NEQ081 protein networkhttps://string-db.org/network/228908.NEQ081NEQ081.
tuf protein networkhttps://string-db.org/network/228908.NEQ082NEQ082; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamil [...]
rps10 protein networkhttps://string-db.org/network/228908.NEQ083NEQ083; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
NEQ084 protein networkhttps://string-db.org/network/228908.NEQ084NEQ084; Conserved hypothetical protein; COG0517: CBS domains; IPR000644: CBS domain.
NEQ085 protein networkhttps://string-db.org/network/228908.NEQ085NEQ085.
NEQ086 protein networkhttps://string-db.org/network/228908.NEQ086NEQ086; Hypothetical protein; PS50318: LYS_RICH; IPR001472: Bipartite nuclear localization signal.
lysS protein networkhttps://string-db.org/network/228908.NEQ087NEQ087; lysyl-tRNA synthetase; LysS [Halobacterium sp]; COG1384: Lysyl-tRNA synthetase class I; IPR001412: Aminoacyl-transfer RNA synthetases class-I; IPR001687: ATP/GTP-binding site motif A (P-l [...]
fen protein networkhttps://string-db.org/network/228908.NEQ088NEQ088; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap str [...]
NEQ089 protein networkhttps://string-db.org/network/228908.NEQ089NEQ089.
NEQ090 protein networkhttps://string-db.org/network/228908.NEQ090NEQ090; Putative polysaccharide biosynthesis protein [Archaeglobus fulgidus]; COG2244: Membrane protein involved in the export of O-antigen and teichoic acid.
rpl10 protein networkhttps://string-db.org/network/228908.NEQ091NEQ091; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
rpl14 protein networkhttps://string-db.org/network/228908.NEQ092NEQ092; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rpl5 protein networkhttps://string-db.org/network/228908.NEQ093NEQ093; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribos [...]
NEQ094 protein networkhttps://string-db.org/network/228908.NEQ094NEQ094.
NEQ095 protein networkhttps://string-db.org/network/228908.NEQ095NEQ095.
NEQ096 protein networkhttps://string-db.org/network/228908.NEQ096NEQ096; Conserved hypothetical protein [Methanopyrus kandleri]; COG1444: Predicted P-loop ATPase fused to an acetyltransferase; IPR000182: GCN5-related N-acetyltransferase.
NEQ097 protein networkhttps://string-db.org/network/228908.NEQ097NEQ097; COG1525: Micrococcal nuclease (thermonuclease) homologs; IPR000080: Staphylococcus nuclease (SNase) homologues.
NEQ098 protein networkhttps://string-db.org/network/228908.NEQ098NEQ098; Predicted transcription regulator; COG1378: Predicted transcriptional regulators; IPR000463: Cytosolic fatty-acid binding protein; IPR002831: Protein of unknown function DUF118.
NEQ099 protein networkhttps://string-db.org/network/228908.NEQ099NEQ099.
NEQ100 protein networkhttps://string-db.org/network/228908.NEQ100NEQ100.
rpl11 protein networkhttps://string-db.org/network/228908.NEQ101NEQ101; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
hisS protein networkhttps://string-db.org/network/228908.NEQ102NEQ102; histidyl-tRNA synthetase [Aeropyrum pernix]; COG0124: Histidyl-tRNA synthetase; IPR002106: Aminoacyl-transfer RNA synthetases class-II; IPR002314: tRNA synthetases, class-II (G, H, P and [...]
atpA protein networkhttps://string-db.org/network/228908.NEQ103NEQ103; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.
NEQ104 protein networkhttps://string-db.org/network/228908.NEQ104NEQ104; Hypothetical protein; COG0608: Single-stranded DNA-specific exonuclease; IPR001472: Bipartite nuclear localization signal.
rps6e protein networkhttps://string-db.org/network/228908.NEQ105NEQ105; Ribosomal protein S6E [Methanopyrus kandeleri]; COG2125: Ribosomal protein S6E (S10); IPR001377: Ribosomal protein S6e; IPR001472: Bipartite nuclear localization signal; Belongs to the eu [...]
NEQ107 protein networkhttps://string-db.org/network/228908.NEQ107NEQ107.
NEQ108 protein networkhttps://string-db.org/network/228908.NEQ108NEQ108; N2,N2-dimethylguanosine tRNA methyltransferase [Aquifex aeolicus]; COG1867: N2,N2-dimethylguanosine tRNA methyltransferase; IPR002905: N2,N2-dimethylguanosine tRNA methyltransferase; Belo [...]
NEQ109 protein networkhttps://string-db.org/network/228908.NEQ109NEQ109; Putative cell division protein [Pyrobaculum aerophilum]; COG1537: Predicted RNA-binding proteins.
NEQ110 protein networkhttps://string-db.org/network/228908.NEQ110NEQ110.
NEQ111 protein networkhttps://string-db.org/network/228908.NEQ111NEQ111; 3' exoribonuclease [Archaeglobus fulgidus]; COG2123: RNase PH-related exoribonuclease; IPR001247: 3' exoribonuclease family.
NEQ112 protein networkhttps://string-db.org/network/228908.NEQ112NEQ112; GTP-binding protein, gtp1/obg family [Pyrococcus furiosus]; COG1163: Predicted GTPase; IPR000765: GTP1/OBG family; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR001472: Bipartite n [...]
NEQ113 protein networkhttps://string-db.org/network/228908.NEQ113NEQ113.
NEQ114 protein networkhttps://string-db.org/network/228908.NEQ114NEQ114; Putative phosphohydrolase [Sulfolobus tokodaii]; COG1078: HD superfamily phosphohydrolases; IPR002819: HD domain; IPR003607: Metal dependent phosphohydrolase HD domain.
NEQ115 protein networkhttps://string-db.org/network/228908.NEQ115NEQ115; Tryptophanyl-tRNA synthetase [Sulfolobus tokodaii]; COG0180: Tryptophanyl-tRNA synthetase; IPR002305: t-RNA synthetase, class Ib; IPR002306: Tryptophanyl-tRNA synthetase; Belongs to the c [...]
NEQ116 protein networkhttps://string-db.org/network/228908.NEQ116NEQ116.
NEQ117 protein networkhttps://string-db.org/network/228908.NEQ117NEQ117; Predicted nucleotide kinase [Pyrococcus horikoshii]; COG1936: Predicted nucleotide kinase (related to CMP and AMP kinases); IPR000623: Shikimate kinase; IPR000765: GTP1/OBG family; IPR001 [...]
NEQ118 protein networkhttps://string-db.org/network/228908.NEQ118NEQ118.
NEQ119 protein networkhttps://string-db.org/network/228908.NEQ119NEQ119; Cell division inhibitor minD homolog [Pyrococcus furiosus]; COG0455: ATPases involved in chromosome partitioning; IPR000707: ParA family ATPase; IPR001687: ATP/GTP-binding site motif A (P [...]
NEQ120 protein networkhttps://string-db.org/network/228908.NEQ120NEQ120.
NEQ121 protein networkhttps://string-db.org/network/228908.NEQ121NEQ121.
NEQ122 protein networkhttps://string-db.org/network/228908.NEQ122NEQ122; Metal dependent hydrolase [Pyrococcus abyssi]; COG1235: Metal-dependent hydrolases of the beta-lactamase superfamily I.
NEQ123 protein networkhttps://string-db.org/network/228908.NEQ123NEQ123; Hypothetical protein; PS50318: LYS_RICH; IPR001472: Bipartite nuclear localization signal.
tgtA protein networkhttps://string-db.org/network/228908.NEQ124NEQ124; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase [...]
flpA protein networkhttps://string-db.org/network/228908.NEQ125NEQ125; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site [...]
gatD protein networkhttps://string-db.org/network/228908.NEQ126NEQ126; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes plac [...]
NEQ126a protein networkhttps://string-db.org/network/228908.NEQ126aNEQ126a; Putative endonuclease III [Pyrococcus abyssi] SPLIT gene see NEQ398.
NEQ127 protein networkhttps://string-db.org/network/228908.NEQ127NEQ127; Putative carbamoyl transferase [Methanococcus jannaschii]; COG2192: Predicted carbamoyl transferase, NodU family; IPR001064: Crystallin; IPR003696: Carbamoyltransferase; IPR001472: Bipart [...]
NEQ128 protein networkhttps://string-db.org/network/228908.NEQ128NEQ128; Conserved hypothetical protein [Thermotoga maratima]; COG1524: Uncharacterized proteins of the AP superfamily.
NEQ129 protein networkhttps://string-db.org/network/228908.NEQ129NEQ129; Conserved hypothetical protein [Desulfovibrio desulfuricans]; COG0719: Predicted membrane components of an uncharacterized iron-regulated ABC-type transporter SufB; IPR000825: Uncharacter [...]
eif1a protein networkhttps://string-db.org/network/228908.NEQ130NEQ130; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subun [...]
NEQ131 protein networkhttps://string-db.org/network/228908.NEQ131NEQ131; Predicted RNA binding protein of the translin family [Pyrobaculum aerophilum]; COG2178: Translin (RNA-binding protein, recombination hotspot binding in eukaryotes); IPR002848: Protein of [...]
NEQ132 protein networkhttps://string-db.org/network/228908.NEQ132NEQ132.
ftsZ protein networkhttps://string-db.org/network/228908.NEQ133NEQ133; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location [...]
NEQ134 protein networkhttps://string-db.org/network/228908.NEQ134NEQ134.
NEQ135 protein networkhttps://string-db.org/network/228908.NEQ135NEQ135.
NEQ136 protein networkhttps://string-db.org/network/228908.NEQ136NEQ136.
NEQ137 protein networkhttps://string-db.org/network/228908.NEQ137NEQ137.
NEQ138 protein networkhttps://string-db.org/network/228908.NEQ138NEQ138.
NEQ139 protein networkhttps://string-db.org/network/228908.NEQ139NEQ139.
NEQ140 protein networkhttps://string-db.org/network/228908.NEQ140NEQ140.
NEQ141 protein networkhttps://string-db.org/network/228908.NEQ141NEQ141; GroEL chaperonin [Methanopyrus kandeleri]; COG0459: Chaperonin GroEL (HSP60 family); IPR002194: Chaperonins TCP-1; IPR002423: TCP-1 (Tailless complex polypeptide)/cpn60 chaperonin family; [...]
NEQ143 protein networkhttps://string-db.org/network/228908.NEQ143NEQ143; Predicted transcription factor [Sulfolobus tokodaii]; COG1813: Predicted transcription factor, homolog of eukaryotic MBF1; IPR001387: Helix-turn-helix motif; IPR001472: Bipartite nuclear [...]
top6B protein networkhttps://string-db.org/network/228908.NEQ144NEQ144; Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
NEQ145 protein networkhttps://string-db.org/network/228908.NEQ145NEQ145.
rpl4 protein networkhttps://string-db.org/network/228908.NEQ146NEQ146; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts [...]
NEQ147 protein networkhttps://string-db.org/network/228908.NEQ147NEQ147; Conserved hypothetical protein [Archaeoglobus fulgidus]; COG0432: Uncharacterized ACR; IPR001602: Uncharacterized protein family UPF0047.
NEQ148 protein networkhttps://string-db.org/network/228908.NEQ148NEQ148; Conserved hypothetical protein containing Radical Sam domain [Pyrococcus horikoshii]; COG1032: Fe-S oxidoreductases family 2; IPR001861: Uncharacterized protein family UPF0004.
adkA protein networkhttps://string-db.org/network/228908.NEQ149NEQ149; Putative adenylate kinase [Pyrococcus furiosus]; COG2019: Archaeal adenylate kinase; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR001472: Bipartite nuclear localization signal; Be [...]
NEQ150 protein networkhttps://string-db.org/network/228908.NEQ150NEQ150; Conserved hypothetical protein [Pyrococcus horikoshii]; IPR001472: Bipartite nuclear localization signal; PFAM Double stranded DNA binding domain; Belongs to the PDCD5 family.
NEQ151 protein networkhttps://string-db.org/network/228908.NEQ151NEQ151.
cca protein networkhttps://string-db.org/network/228908.NEQ152NEQ152; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to th [...]
NEQ153 protein networkhttps://string-db.org/network/228908.NEQ153NEQ153.
NEQ154 protein networkhttps://string-db.org/network/228908.NEQ154NEQ154.
NEQ155 protein networkhttps://string-db.org/network/228908.NEQ155NEQ155; Hypothetical protein; COG1287: Uncharacterized membrane protein, required for N-linked glycosylation; IPR001680: G-protein beta WD-40 repeats.
NEQ156 protein networkhttps://string-db.org/network/228908.NEQ156NEQ156; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
NEQ157 protein networkhttps://string-db.org/network/228908.NEQ157NEQ157; GTP-binding protein [Pyrococcus horikoshii]; COG1084: Predicted GTPase; IPR000765: GTP1/OBG family; IPR001687: ATP/GTP-binding site motif A (P-loop).
NEQ158 protein networkhttps://string-db.org/network/228908.NEQ158NEQ158; Conserved hypothetical protein [Pyrococcus furiosus]; COG2411: Uncharacterized ACR.
NEQ159 protein networkhttps://string-db.org/network/228908.NEQ159NEQ159; Phosphatidylethanolamine binding protein [Sulfolobus tokodaii]; COG1881: Phospholipid-binding protein; IPR003015: Myc-type, helix-loop-helix dimerization domain; IPR001858: Phosphatidylet [...]
NEQ160 protein networkhttps://string-db.org/network/228908.NEQ160NEQ160.
NEQ161 protein networkhttps://string-db.org/network/228908.NEQ161NEQ161; PS50313: GLU_RICH.
NEQ162 protein networkhttps://string-db.org/network/228908.NEQ162NEQ162; Conserved hypothetical protein [aquifex aeolicus]; COG0628: Predicted permease; PS50324: SER_RICH; IPR003015: Myc-type, helix-loop-helix dimerization domain; IPR002549: Domain of unknown [...]
NEQ163 protein networkhttps://string-db.org/network/228908.NEQ163NEQ163.
NEQ164 protein networkhttps://string-db.org/network/228908.NEQ164NEQ164.
NEQ165 protein networkhttps://string-db.org/network/228908.NEQ165NEQ165; Hypothetical protein; COG2263: Predicted RNA methylase; IPR000051: SAM (and some other nucleotide) binding motif; IPR002052: N-6 Adenine-specific DNA methylase.
NEQ166 protein networkhttps://string-db.org/network/228908.NEQ166NEQ166; COG1394: Archaeal/vacuolar-type H+-ATPase subunit D; IPR002699: ATP synthase subunit D; IPR001472: Bipartite nuclear localization signal.
NEQ168 protein networkhttps://string-db.org/network/228908.NEQ168NEQ168; Preprotein translocase subunit SecY [Methanopyrus kandleri]; COG0201: Preprotein translocase subunit SecY; IPR002208: SecY protein; Belongs to the SecY/SEC61-alpha family.
NEQ169 protein networkhttps://string-db.org/network/228908.NEQ169NEQ169; Type II/IV secretion system protein [Archaeoglobus fulgidus]; COG0630: Predicted ATPases involved in pili and flagella biosynthesis, VirB11 family; IPR000194: ATP synthase alpha and beta [...]
rfcS protein networkhttps://string-db.org/network/228908.NEQ170NEQ170; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily.
NEQ171 protein networkhttps://string-db.org/network/228908.NEQ171NEQ171.
NEQ172 protein networkhttps://string-db.org/network/228908.NEQ172NEQ172; Glycosyl transferase [Streptococcus thermophilus]; COG0463: Glycosyltransferases involved in cell wall biogenesis; IPR001173: Glycosyl transferase, family 2.
NEQ173 protein networkhttps://string-db.org/network/228908.NEQ173NEQ173; DNA-directed RNA polymerase subunit B [Thermococcus celer]; COG0085: DNA-directed RNA polymerase beta subunit/140 kD subunit (split gene in Mjan, Mthe, Aful); IPR001572: RNA polymerases b [...]
NEQ174 protein networkhttps://string-db.org/network/228908.NEQ174NEQ174; Conserved hypothetical protein [Pyrococcus horikoshii]; COG0467: RecA-superfamily ATPases implicated in signal transduction; IPR001687: ATP/GTP-binding site motif A (P-loop); Belongs to t [...]
NEQ175 protein networkhttps://string-db.org/network/228908.NEQ175NEQ175; Predicted permease [Methanococcus jannaschii]; COG0577: ABC-type transport systems, involved in lipoprotein release, permease components; IPR002453: Beta tubulin; IPR003838: DUF214; PS503 [...]
rps27ae protein networkhttps://string-db.org/network/228908.NEQ176NEQ176; SSU ribosomal protein S27AE; [Pyrococcus furiosus]; COG1998: Ribosomal protein S27AE; IPR002906: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family.
thrS protein networkhttps://string-db.org/network/228908.NEQ177NEQ177; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Al [...]
NEQ178 protein networkhttps://string-db.org/network/228908.NEQ178NEQ178; LSU ribosomal protein L14E [Methanococcus jannaschii]; COG2163: Ribosomal protein L14E; IPR002784: Ribosomal protein L14.
NEQ179 protein networkhttps://string-db.org/network/228908.NEQ179NEQ179; Ribosomal protein L7Ae/L30E/S12e/Gadd45 family [Methanococcus jannaschii]; COG1911: Ribosomal protein L30E; IPR000955: Ribosomal protein L7AE; IPR000231: Ribosomal protein L30e.
NEQ180 protein networkhttps://string-db.org/network/228908.NEQ180NEQ180; Putative transcription factor [Methanococcus vannielii]; COG0195: Transcription terminator.
rpl15e protein networkhttps://string-db.org/network/228908.NEQ181NEQ181; LSU ribosomal protein L15E; [Pyrococcus furiosus]; COG1632: Ribosomal protein L15E; IPR000439: Ribosomal protein L15e; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR001472: Biparti [...]
rpoL protein networkhttps://string-db.org/network/228908.NEQ182NEQ182; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA [...]
rpl44e protein networkhttps://string-db.org/network/228908.NEQ183NEQ183; Binds to the 23S rRNA.
NEQ184 protein networkhttps://string-db.org/network/228908.NEQ184NEQ184; Conserved hypothetical protein [Archaeoglobus fulgidus]; COG1097: RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain); IPR000958: KH domain.
gatB protein networkhttps://string-db.org/network/228908.NEQ185NEQ185; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of [...]
NEQ186 protein networkhttps://string-db.org/network/228908.NEQ186NEQ186; 26S proteasome subunit P45 family [Sulfolobus tokodaii]; COG1222: ATP-dependent 26S proteasome regulatory subunit; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR001939: AAA-protein [...]
rps19e protein networkhttps://string-db.org/network/228908.NEQ187NEQ187; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
NEQ188 protein networkhttps://string-db.org/network/228908.NEQ188NEQ188.
NEQ189 protein networkhttps://string-db.org/network/228908.NEQ189NEQ189; Conserved hypothetical protein [Clostridium perfringens]; COG1253: Uncharacterized CBS domain-containing proteins; IPR002550: Domain of unknown function DUF21; IPR000644: CBS domain.
ilvE protein networkhttps://string-db.org/network/228908.NEQ190NEQ190; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
NEQ191 protein networkhttps://string-db.org/network/228908.NEQ191NEQ191; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidati [...]
NEQ192 protein networkhttps://string-db.org/network/228908.NEQ192NEQ192; Prephenate dehydratase [Archaeoglobus fulgidus]; COG0077: Prephenate dehydratase; COG0287: Prephenate dehydrogenase; IPR001086: Prephenate dehydratase (PDT); IPR002701: Chorismate mutase; [...]
NEQ193 protein networkhttps://string-db.org/network/228908.NEQ193NEQ193.
NEQ194 protein networkhttps://string-db.org/network/228908.NEQ194NEQ194.
NEQ195 protein networkhttps://string-db.org/network/228908.NEQ195NEQ195; Glycosyltransferase [Actinobacillus actinomycetemcomitans]; COG0438: Predicted glycosyltransferases; IPR001296: Glycosyl transferases group 1.
NEQ196 protein networkhttps://string-db.org/network/228908.NEQ196NEQ196.
NEQ197 protein networkhttps://string-db.org/network/228908.NEQ197NEQ197.
NEQ198 protein networkhttps://string-db.org/network/228908.NEQ198NEQ198; Mechanosensitive ion channel [Methanococcus jannaschii]; COG0668: Small-conductance mechanosensitive channel; IPR001880: Uncharacterized protein family UPF0003.
NEQ199 protein networkhttps://string-db.org/network/228908.NEQ199NEQ199; Replication factor A related protein [Methanococcus jannaschii]; COG1599: Replication factor A large subunit and related ssDNA-binding proteins; IPR002309: tRNA synthetases, class II (D, [...]
NEQ200 protein networkhttps://string-db.org/network/228908.NEQ200NEQ200.
rpl12 protein networkhttps://string-db.org/network/228908.NEQ201NEQ201; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.
psmB protein networkhttps://string-db.org/network/228908.NEQ203NEQ203; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
rpl22 protein networkhttps://string-db.org/network/228908.NEQ204NEQ204; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
endA protein networkhttps://string-db.org/network/228908.NEQ205NEQ205; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic [...]
NEQ206 protein networkhttps://string-db.org/network/228908.NEQ206NEQ206; Conserved hypothetical protein with predicted RNA binding PUA domain [Pyrobaculum aerophilum]; COG2016: PUA domain (predicted RNA-binding domain); IPR002478: PUA domain.
rpl13 protein networkhttps://string-db.org/network/228908.NEQ207NEQ207; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
NEQ208 protein networkhttps://string-db.org/network/228908.NEQ208NEQ208; Arginyl-tRNA synthetase [Lactobacillus gasseri]; COG0018: Arginyl-tRNA synthetase; IPR002453: Beta tubulin; IPR001412: Aminoacyl-transfer RNA synthetases class-I; IPR001278: Arginyl-tRNA [...]
NEQ209 protein networkhttps://string-db.org/network/228908.NEQ209NEQ209; Hypothetical protein; COG0419: ATPase involved in DNA repair.
proS protein networkhttps://string-db.org/network/228908.NEQ210NEQ210; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
NEQ211 protein networkhttps://string-db.org/network/228908.NEQ211NEQ211; alanyl-tRNA synthetase [Pyrococcus abyssi]; COG0013: Alanyl-tRNA synthetase; IPR002318: Alanyl-tRNA synthetase.
NEQ212 protein networkhttps://string-db.org/network/228908.NEQ212NEQ212; Ribosomal protein 15A isolog [Pyrococcus furiosus]; COG1439: Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module; IPR002851: Protein of unknown functio [...]
NEQ213 protein networkhttps://string-db.org/network/228908.NEQ213NEQ213; HIT family protein [Methanosarcina acetivorans]; COG0537: Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; IPR001310: HIT (Histidine triad) family.
NEQ214 protein networkhttps://string-db.org/network/228908.NEQ214NEQ214; Hypothetical protein; COG1361: S-layer domain; IPR001472: Bipartite nuclear localization signal.
NEQ215 protein networkhttps://string-db.org/network/228908.NEQ215NEQ215.
NEQ216 protein networkhttps://string-db.org/network/228908.NEQ216NEQ216.
NEQ217 protein networkhttps://string-db.org/network/228908.NEQ217NEQ217; ATP synthase subunit C [Methanopyrus kandeleri]; COG0636: F0F1-type ATP synthase c subunit/Archaeal/vacuolar-type H+-ATPase subunit K; IPR002379: ATP synthase subunit C; IPR000245: Vacuol [...]
NEQ218 protein networkhttps://string-db.org/network/228908.NEQ218NEQ218.
rps27e protein networkhttps://string-db.org/network/228908.NEQ219NEQ219; Ribosomal protein S27E [Methanopyrus kandeleri]; COG2051: Ribosomal protein S27E; IPR000592: Ribosomal protein S27E.
ef1b protein networkhttps://string-db.org/network/228908.NEQ220NEQ220; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
NEQ221 protein networkhttps://string-db.org/network/228908.NEQ221NEQ221.
NEQ222 protein networkhttps://string-db.org/network/228908.NEQ222NEQ222.
NEQ223 protein networkhttps://string-db.org/network/228908.NEQ223NEQ223; Agmatinase [Archaeoglobus fulgidus]; COG0010: Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; IPR000287: Arginase family; Belongs to the arginase family.
NEQ224 protein networkhttps://string-db.org/network/228908.NEQ224NEQ224; Hypothetical protein; IPR001472: Bipartite nuclear localization signal.
NEQ225 protein networkhttps://string-db.org/network/228908.NEQ225NEQ225.
NEQ226 protein networkhttps://string-db.org/network/228908.NEQ226NEQ226; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring o [...]
rps14 protein networkhttps://string-db.org/network/228908.NEQ227NEQ227; Binds 16S rRNA, required for the assembly of 30S particles.
taw22 protein networkhttps://string-db.org/network/228908.NEQ228NEQ228; Catalyzes both the N1-methylation of guanosine and the C7- methylation of 4-demethylwyosine (imG-14) at position 37 in tRNA(Phe). Belongs to the class I-like SAM-binding methyltransferase [...]
NEQ229 protein networkhttps://string-db.org/network/228908.NEQ229NEQ229; Transcriptional regulator Ptr2 [Methanocaldococcus jannaschii]; COG1522: Transcriptional regulators; IPR000485: Bacterial regulatory proteins, AsnC family.
NEQ230 protein networkhttps://string-db.org/network/228908.NEQ230NEQ230; isoleucyl-tRNA synthetase [Pyrococcus furiosus]; COG0060: Isoleucyl-tRNA synthetase; IPR002300: t-RNA synthetase, class Ia; IPR002301: Isoleucyl-tRNA synthetase; IPR001412: Aminoacyl-tran [...]
spt4 protein networkhttps://string-db.org/network/228908.NEQ231NEQ231; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
NEQ232 protein networkhttps://string-db.org/network/228908.NEQ232NEQ232.
NEQ233 protein networkhttps://string-db.org/network/228908.NEQ233NEQ233.
NEQ234 protein networkhttps://string-db.org/network/228908.NEQ234NEQ234; Magnesium chelatase subunit ChII [Pyrococcus furiosus]; COG0714: MoxR-like ATPases; IPR003593: AAA ATPase superfamily.
NEQ235 protein networkhttps://string-db.org/network/228908.NEQ235NEQ235; Conserved hypothetical protein [Methanothermobacter thermautotrophicus]; COG1499: NMD protein affecting ribosome stability and mRNA decay.
NEQ236 protein networkhttps://string-db.org/network/228908.NEQ236NEQ236; Hypothetical protein; PS50325: THR_RICH; IPR001687: ATP/GTP-binding site motif A (P-loop); PS50313: GLU_RICH.
NEQ237 protein networkhttps://string-db.org/network/228908.NEQ237NEQ237.
NEQ238 protein networkhttps://string-db.org/network/228908.NEQ238NEQ238; Conserved hypothetical protein [Methanococcus jannaschii]; COG2890: Predicted rRNA or tRNA methylase; IPR000051: SAM (and some other nucleotide) binding motif; IPR002052: N-6 Adenine-spec [...]
leuS protein networkhttps://string-db.org/network/228908.NEQ239NEQ239; Isoleucine tRNA synthetase [Methanococcus jannaschii]; COG0495: Leucyl-tRNA synthetase; COG0143: Methionyl-tRNA synthetase; IPR002300: t-RNA synthetase, class Ia; IPR002308: Cysteinyl-tRN [...]
polB protein networkhttps://string-db.org/network/228908.NEQ240NEQ240; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which i [...]
rpl6 protein networkhttps://string-db.org/network/228908.NEQ241NEQ241; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site o [...]
rps7 protein networkhttps://string-db.org/network/228908.NEQ242NEQ242; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the [...]
NEQ243 protein networkhttps://string-db.org/network/228908.NEQ243NEQ243.
pth protein networkhttps://string-db.org/network/228908.NEQ244NEQ244; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
gatE protein networkhttps://string-db.org/network/228908.NEQ245NEQ245; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes plac [...]
NEQ246 protein networkhttps://string-db.org/network/228908.NEQ246NEQ246.
rps4 protein networkhttps://string-db.org/network/228908.NEQ247NEQ247; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
NEQ248 protein networkhttps://string-db.org/network/228908.NEQ248NEQ248; 3' exoribonuclease [Pyrococcus furiosus]; COG0689: RNase PH; IPR001247: 3' exoribonuclease family.
NEQ249 protein networkhttps://string-db.org/network/228908.NEQ249NEQ249.
NEQ250 protein networkhttps://string-db.org/network/228908.NEQ250NEQ250.
valS protein networkhttps://string-db.org/network/228908.NEQ252NEQ252; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'pos [...]
NEQ253 protein networkhttps://string-db.org/network/228908.NEQ253NEQ253.
NEQ254 protein networkhttps://string-db.org/network/228908.NEQ254NEQ254.
NEQ255 protein networkhttps://string-db.org/network/228908.NEQ255NEQ255.
rad50 protein networkhttps://string-db.org/network/228908.NEQ256NEQ256; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the r [...]
rpl24 protein networkhttps://string-db.org/network/228908.NEQ257NEQ257; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
NEQ258 protein networkhttps://string-db.org/network/228908.NEQ258NEQ258; Hypothetical protein; COG1873: Uncharacterized ACR.
NEQ259 protein networkhttps://string-db.org/network/228908.NEQ259NEQ259.
NEQ260 protein networkhttps://string-db.org/network/228908.NEQ260NEQ260.
NEQ261 protein networkhttps://string-db.org/network/228908.NEQ261NEQ261; Hypothetical protein; COG1676: tRNA splicing endonuclease; IPR002827: tRNA intron endonuclease.
rpl29 protein networkhttps://string-db.org/network/228908.NEQ262NEQ262; Putative ribosomal protein; COG0255: Ribosomal protein L29; IPR001854: Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
NEQ263 protein networkhttps://string-db.org/network/228908.NEQ263NEQ263; H+ transporting ATP synthase, subunit B [Methanococcus jannaschii]; COG1156: Archaeal/vacuolar-type H+-ATPase subunit B; IPR000194: ATP synthase alpha and beta subunit, N-terminal; IPR003 [...]
NEQ264 protein networkhttps://string-db.org/network/228908.NEQ264NEQ264; Translation factor sui1 homolog [Pyrococcus furiosus]; COG0023: Translation initiation factor (SUI1); IPR001950: Translation initiation factor SUI1; IPR001472: Bipartite nuclear localizat [...]
NEQ265 protein networkhttps://string-db.org/network/228908.NEQ265NEQ265; Hypothetical protein; IPR000847: Bacterial regulatory protein, LysR family; IPR001472: Bipartite nuclear localization signal.
NEQ266 protein networkhttps://string-db.org/network/228908.NEQ266NEQ266.
NEQ267 protein networkhttps://string-db.org/network/228908.NEQ267NEQ267; Putative flaggella related protein [Methanococcus jannaschii] SPLIT see NEQ268; COG2064: Predicted membrane protein.
NEQ268 protein networkhttps://string-db.org/network/228908.NEQ268NEQ268; Putative flaggella related protein [Archaeoglobus fulgidus] SPLIT see NEQ267; COG2064: Predicted membrane protein; PS50317: ILE_RICH.
NEQ270 protein networkhttps://string-db.org/network/228908.NEQ270NEQ270; Elongation factor Tu [Pyrococcus abyssi]; COG0050: GTPases - translation elongation factors; IPR000795: GTP-binding elongation factor; IPR001687: ATP/GTP-binding site motif A (P-loop).
NEQ271 protein networkhttps://string-db.org/network/228908.NEQ271NEQ271.
NEQ273 protein networkhttps://string-db.org/network/228908.NEQ273NEQ273.
rps8 protein networkhttps://string-db.org/network/228908.NEQ274NEQ274; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribo [...]
NEQ275 protein networkhttps://string-db.org/network/228908.NEQ275NEQ275.
tfb protein networkhttps://string-db.org/network/228908.NEQ276NEQ276; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
NEQ277 protein networkhttps://string-db.org/network/228908.NEQ277NEQ277; Hypothetical protein; COG2450: Uncharacterized ACR.
NEQ278 protein networkhttps://string-db.org/network/228908.NEQ278NEQ278.
NEQ279 protein networkhttps://string-db.org/network/228908.NEQ279NEQ279.
NEQ280 protein networkhttps://string-db.org/network/228908.NEQ280NEQ280.
NEQ281 protein networkhttps://string-db.org/network/228908.NEQ281NEQ281; Conserved hypothetical protein; COG1750: Archaeal serine proteases; IPR001687: ATP/GTP-binding site motif A (P-loop).
NEQ282 protein networkhttps://string-db.org/network/228908.NEQ282NEQ282; Mini chromosome maintenance (MCM) protein [Methanothermobacter thermautotrophicus]; COG1241: Predicted ATPase involved in replication control, Cdc46/Mcm family; IPR001208: MCM family; IPR [...]
NEQ283 protein networkhttps://string-db.org/network/228908.NEQ283NEQ283; Conserved hypothetical protein [Archaeoglobus fulgidus]; COG0037: Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; IPR000463: Cytosolic fatty-acid binding pro [...]
NEQ284 protein networkhttps://string-db.org/network/228908.NEQ284NEQ284.
NEQ289 protein networkhttps://string-db.org/network/228908.NEQ289NEQ289.
NEQ291 protein networkhttps://string-db.org/network/228908.NEQ291NEQ291; Hypothetical protein; IPR001472: Bipartite nuclear localization signal.
NEQ292 protein networkhttps://string-db.org/network/228908.NEQ292NEQ292.
truD protein networkhttps://string-db.org/network/228908.NEQ293NEQ293; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
NEQ294 protein networkhttps://string-db.org/network/228908.NEQ294NEQ294; Conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71.
NEQ295 protein networkhttps://string-db.org/network/228908.NEQ295NEQ295; Nucleolar protein [Pyrococcus abyssi]; COG0144: tRNA and rRNA cytosine-C5-methylases; IPR000051: SAM (and some other nucleotide) binding motif; IPR001678: NOL1/NOP2/sun family; IPR001687: [...]
NEQ296 protein networkhttps://string-db.org/network/228908.NEQ296NEQ296.
rpl34e protein networkhttps://string-db.org/network/228908.NEQ297NEQ297; LSU ribosomal protein L34E [Methanococcus jannaschii]; COG2174: Ribosomal protein L34E; IPR001284: Ribosomal protein L34e; IPR001472: Bipartite nuclear localization signal; Belongs to the [...]
NEQ298 protein networkhttps://string-db.org/network/228908.NEQ298NEQ298; Hypothetical protein [Pyrococcus horikoshii]; IPR001472: Bipartite nuclear localization signal.
NEQ299 protein networkhttps://string-db.org/network/228908.NEQ299NEQ299; ABC transport protein [Pyrococcus horikoshii]; COG1245: RNase L inhibitor homolog, predicted ATPase; IPR001450: 4Fe-4S ferredoxin, iron-sulfur binding domain; IPR001687: ATP/GTP-binding s [...]
NEQ300 protein networkhttps://string-db.org/network/228908.NEQ300NEQ300.
NEQ301 protein networkhttps://string-db.org/network/228908.NEQ301NEQ301.
gltX protein networkhttps://string-db.org/network/228908.NEQ302NEQ302; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
rpl35ae protein networkhttps://string-db.org/network/228908.NEQ303NEQ303; LSU ribosomal protein L35AE [Pyrococcus abyssi]; COG2451: Ribosomal protein L35AE/L33A; IPR001780: Ribosomal protein L35Ae; Belongs to the eukaryotic ribosomal protein eL33 family.
NEQ304 protein networkhttps://string-db.org/network/228908.NEQ304NEQ304.
NEQ305 protein networkhttps://string-db.org/network/228908.NEQ305NEQ305; Archaeosine tRNA ribosyl transferase [Methanosarcina mazei] SPLIT see NEQ143; COG1370: Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit; IPR001687: ATP/ [...]
NEQ306 protein networkhttps://string-db.org/network/228908.NEQ306NEQ306; 3-oxoacyl- reductase [Aquifex aeolicus]; COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); IPR002198: Short-chain dehydrogenase/reducta [...]
NEQ307 protein networkhttps://string-db.org/network/228908.NEQ307NEQ307; Nucleoside diphosphate kinase [Pyrobaculum aerophilum]; COG0105: Nucleoside diphosphate kinase; IPR001564: Nucleoside diphosphate kinase.
NEQ308 protein networkhttps://string-db.org/network/228908.NEQ308NEQ308; seryl-tRNA synthetase [Sulfolobus tokodaii]; COG0172: Seryl-tRNA synthetase; IPR002106: Aminoacyl-transfer RNA synthetases class-II; IPR002317: Seryl-tRNA synthetase; IPR003364: Seryl-tRN [...]
NEQ309 protein networkhttps://string-db.org/network/228908.NEQ309NEQ309.
NEQ310 protein networkhttps://string-db.org/network/228908.NEQ310NEQ310; Conserved hypothetical protein [Pyrococcus abyssi]; COG3270: Uncharacterized ACR; IPR001472: Bipartite nuclear localization signal.
rpl30 protein networkhttps://string-db.org/network/228908.NEQ311NEQ311; LSU ribosomal protein L30P [Methanococcus jannaschii]; COG1841: Ribosomal protein L30/L7E; IPR000517: Ribosomal protein L30.
NEQ312 protein networkhttps://string-db.org/network/228908.NEQ312NEQ312.
NEQ313 protein networkhttps://string-db.org/network/228908.NEQ313NEQ313; Conserved hypothetical protein [Methanosarcina mazei]; COG1412: Uncharacterized proteins of PilT N-term./Vapc superfamily.
NEQ314 protein networkhttps://string-db.org/network/228908.NEQ314NEQ314; Hypothetical protein; COG1873: Uncharacterized ACR.
NEQ315 protein networkhttps://string-db.org/network/228908.NEQ315NEQ315; Proteinase IV [Methanococcus jannaschii]; COG0616: Periplasmic serine proteases (ClpP class); IPR002142: Peptidase family U7.
dcd protein networkhttps://string-db.org/network/228908.NEQ316NEQ316; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
rpl15 protein networkhttps://string-db.org/network/228908.NEQ317NEQ317; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
NEQ318 protein networkhttps://string-db.org/network/228908.NEQ318NEQ318; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA [...]
rpl7ae protein networkhttps://string-db.org/network/228908.NEQ319NEQ319; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
rps17e protein networkhttps://string-db.org/network/228908.NEQ320NEQ320; SSU ribosomal protein S17E [Pyrococcus horikoshii]; COG1383: Ribosomal protein S17E; IPR001472: Bipartite nuclear localization signal; Belongs to the eukaryotic ribosomal protein eS17 fam [...]
NEQ321 protein networkhttps://string-db.org/network/228908.NEQ321NEQ321; Zn finger containing protein [Methanopyrus kandeleri]; COG1779: C4-type Zn finger.
NEQ322 protein networkhttps://string-db.org/network/228908.NEQ322NEQ322.
eif2b protein networkhttps://string-db.org/network/228908.NEQ323NEQ323; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
NEQ324 protein networkhttps://string-db.org/network/228908.NEQ324NEQ324; DNA topoisomerase I [Pyrococcus horikoshii] SPLIT see NEQ045; COG0550: Topoisomerase IA; IPR000380: Prokaryotic DNA topoisomerase I.
taw3 protein networkhttps://string-db.org/network/228908.NEQ325NEQ325; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce [...]
rps17 protein networkhttps://string-db.org/network/228908.NEQ326NEQ326; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
NEQ327 protein networkhttps://string-db.org/network/228908.NEQ327NEQ327.
NEQ328 protein networkhttps://string-db.org/network/228908.NEQ328NEQ328; Transcriptional regulatory protein, asnC family [Pyrococcus furiosus]; COG1522: Transcriptional regulators; IPR000485: Bacterial regulatory proteins, AsnC family.
NEQ329 protein networkhttps://string-db.org/network/228908.NEQ329NEQ329; dCTP deaminase [Methanosarcina acetivorans]; COG0717: Deoxycytidine deaminase; IPR003232: dCTP Deaminase.
NEQ330 protein networkhttps://string-db.org/network/228908.NEQ330NEQ330.
NEQ331 protein networkhttps://string-db.org/network/228908.NEQ331NEQ331.
NEQ332 protein networkhttps://string-db.org/network/228908.NEQ332NEQ332.
truA protein networkhttps://string-db.org/network/228908.NEQ333NEQ333; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
NEQ334 protein networkhttps://string-db.org/network/228908.NEQ334NEQ334; Nucleotide binding protein [Pyrococcus furiosus]; COG1491: Predicted RNA-binding protein; IPR001472: Bipartite nuclear localization signal.
NEQ335 protein networkhttps://string-db.org/network/228908.NEQ335NEQ335.
NEQ336 protein networkhttps://string-db.org/network/228908.NEQ336NEQ336.
NEQ337 protein networkhttps://string-db.org/network/228908.NEQ337NEQ337; Putative methyl transferase [Methanococcus jannaschii]; COG2519: Predicted SAM-dependent methyltransferase involved in tRNA-Met maturation; IPR000051: SAM (and some other nucleotide) bind [...]
rpoN protein networkhttps://string-db.org/network/228908.NEQ338NEQ338; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polym [...]
NEQ339 protein networkhttps://string-db.org/network/228908.NEQ339NEQ339; Conserved hypothetical protein [Methanococcus jannaschii]; COG1994: Zn-dependent proteases; IPR000130: Neutral zinc metallopeptidases, zinc-binding region.
NEQ340 protein networkhttps://string-db.org/network/228908.NEQ340NEQ340; Hypothetical protein; COG1011: Predicted hydrolases of the HAD superfamily; IPR001454: Haloacid dehalogenase/epoxide hydrolase family.
dnaG protein networkhttps://string-db.org/network/228908.NEQ341NEQ341; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA [...]
NEQ342 protein networkhttps://string-db.org/network/228908.NEQ342NEQ342; Nucleolar protein [Sulfolobus tokodaii]; COG1498: Protein implicated in ribosomal biogenesis, Nop56p homolog; IPR002687: Putative snoRNA binding domain.
NEQ343 protein networkhttps://string-db.org/network/228908.NEQ343NEQ343; Hypothetical protein [Pyrococcus abyssi]; COG0693: Putative intracellular protease/amidase.
NEQ344 protein networkhttps://string-db.org/network/228908.NEQ344NEQ344; Small heat shock protein [Aquifex aeolicus]; COG0071: Molecular chaperone (small heat shock protein); IPR002068: Heat shock hsp20 (alpha crystallin) proteins family; Belongs to the small [...]
NEQ345 protein networkhttps://string-db.org/network/228908.NEQ345NEQ345; Ribonucleoside triphosphate reductase; COG1328: Oxygen-sensitive ribonucleoside-triphosphate reductase.
NEQ345a protein networkhttps://string-db.org/network/228908.NEQ345aNEQ345a; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact les [...]
rpl18a protein networkhttps://string-db.org/network/228908.NEQ346NEQ346; LSU ribosomal protein LX [Pyrococcus horikowshii]; COG2157: Ribosomal protein L20A (L18A); IPR002768: Ribosomal LX protein.
NEQ347 protein networkhttps://string-db.org/network/228908.NEQ347NEQ347; Conserved hypothetical protein [Methanosarcina acetivorans]; COG1355: Predicted dioxygenase; IPR002737: Protein of unknown function DUF52; Belongs to the MEMO1 family.
NEQ348 protein networkhttps://string-db.org/network/228908.NEQ348NEQ348; Putative histone A2 [Methanococcus jannaschii]; COG2036: Histones H3 and H4; IPR000947: Histone-like transcription factor (CBF/NF-Y) and archaeal histone, subunit A; IPR000166: Histone-fo [...]
NEQ349 protein networkhttps://string-db.org/network/228908.NEQ349NEQ349; ATP-dependent protease La [Archaeoglobus fulgidus]; COG1067: Predicted ATP-dependent protease; IPR001984: ATP-dependent serine proteases, Lon family; IPR001687: ATP/GTP-binding site motif [...]
NEQ350 protein networkhttps://string-db.org/network/228908.NEQ350NEQ350; Conserved hypothetical protein [Thermoplasma volcanium]; COG2151: Putative aromatic ring hydroxylating enzyme; IPR002744: Domain of unknown function DUF59.
NEQ351 protein networkhttps://string-db.org/network/228908.NEQ351NEQ351; Hypothetical protein; COG2522: Predicted transcriptional regulator.
NEQ352 protein networkhttps://string-db.org/network/228908.NEQ352NEQ352; Conserved hypothetical protein [Pyrococcus furiosus]; COG1967: Predicted membrane proteins; IPR002749: Membrane protein of unknown function DUF63.
NEQ353 protein networkhttps://string-db.org/network/228908.NEQ353NEQ353; Hypothetical protein; IPR001472: Bipartite nuclear localization signal.
NEQ354 protein networkhttps://string-db.org/network/228908.NEQ354NEQ354; Hypothetical protein; COG1196: Chromosome segregation ATPases.
NEQ355 protein networkhttps://string-db.org/network/228908.NEQ355NEQ355; Conserved hypothetical protein [Archaeoglobus fulgidus].
NEQ356 protein networkhttps://string-db.org/network/228908.NEQ356NEQ356.
NEQ357 protein networkhttps://string-db.org/network/228908.NEQ357NEQ357.
NEQ358 protein networkhttps://string-db.org/network/228908.NEQ358NEQ358; Conserved hypothetical protein [Pyrococcus abyssi]; COG1407: Predicted ICC-like phosphoesterases; IPR000934: Serine/threonine specific protein phosphatase.
rps28e protein networkhttps://string-db.org/network/228908.NEQ359NEQ359; SSU ribosomal protein S28E [Pyrococcus abyssi]; COG2053: Ribosomal protein S28E/S33; IPR000289: Ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
NEQ360 protein networkhttps://string-db.org/network/228908.NEQ360NEQ360; Glu-tRNA amidotransferase, subunit A [Archaeoglobus fulgidus]; COG0154: Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; IPR000120: Amidase.
rpl2 protein networkhttps://string-db.org/network/228908.NEQ361NEQ361; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested [...]
NEQ362 protein networkhttps://string-db.org/network/228908.NEQ362NEQ362.
albA protein networkhttps://string-db.org/network/228908.NEQ363NEQ363; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it [...]
NEQ364 protein networkhttps://string-db.org/network/228908.NEQ364NEQ364; LSU ribosomal protein L31E [Methanococcus jannaschii]; COG2097: Ribosomal protein L31E; IPR000054: Ribosomal protein L31e.
NEQ365 protein networkhttps://string-db.org/network/228908.NEQ365NEQ365; Hypothetical protein; PS50313: GLU_RICH; IPR001697: Pyruvate kinase family.
NEQ366 protein networkhttps://string-db.org/network/228908.NEQ366NEQ366; GTP-binding protein [Pyrococcus horikoshii]; COG1161: Predicted GTPases; IPR002917: GTP-binding protein (HSR1-related); IPR001687: ATP/GTP-binding site motif A (P-loop).
NEQ367 protein networkhttps://string-db.org/network/228908.NEQ367NEQ367; Nucleotidyl transferase [Pyrococcus furiosus]; COG1056: Nicotinamide mononucleotide adenylyltransferase; IPR001472: Bipartite nuclear localization signal.
NEQ368 protein networkhttps://string-db.org/network/228908.NEQ368NEQ368; Putative endonuclease [Methanococcus jannaschii].
NEQ369 protein networkhttps://string-db.org/network/228908.NEQ369NEQ369; DEAD box helicase [Sulfolobus solfataricus]; COG1061: DNA or RNA helicases of superfamily II; IPR001410: DEAD/DEAH box helicase; IPR001650: Helicase C-terminal domain.
NEQ370 protein networkhttps://string-db.org/network/228908.NEQ370NEQ370; DNA-directed RNA polymerase, subunit E' [Methanococcus jannaschii]; COG1095: DNA-directed RNA polymerase subunit E'; IPR003029: S1 RNA binding domain.
NEQ371 protein networkhttps://string-db.org/network/228908.NEQ371NEQ371; Conserved hypothetical protein [Sulfolobus solfataricus]; COG0419: ATPase involved in DNA repair.
NEQ372 protein networkhttps://string-db.org/network/228908.NEQ372NEQ372; Uracil DNA glycosylase [Sulfolobus tokodaii]; COG1573: Uracil-DNA glycosylase.
NEQ373 protein networkhttps://string-db.org/network/228908.NEQ373NEQ373; Ferredoxin [Thermococcus litoralis]; COG1141: Ferredoxin 1; IPR001450: 4Fe-4S ferredoxin, iron-sulfur binding domain; IPR000345: Cytochrome c family heme-binding site.
rps3ae protein networkhttps://string-db.org/network/228908.NEQ375NEQ375; Ribosomal protein S3AE [Methanopyrus kandleri]; COG1890: Ribosomal protein S3AE; IPR001593: Ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
NEQ376 protein networkhttps://string-db.org/network/228908.NEQ376NEQ376.
NEQ377 protein networkhttps://string-db.org/network/228908.NEQ377NEQ377; Transcription factor S-II [Sulfolobus tokodaii]; COG1594: DNA-directed RNA polymerase subunit M/Transcription elongation factor TFIIS; IPR001222: TFIIS zinc ribbon domain; IPR001472: Bipa [...]
NEQ378 protein networkhttps://string-db.org/network/228908.NEQ378NEQ378; Putative metallo-beta lactamase [Pyrococcus abyssi]; COG2220: Predicted Zn-dependent hydrolases of the beta-lactamase fold; IPR001279: Metallo-beta-lactamase superfamily; Belongs to the U [...]
rpl19e protein networkhttps://string-db.org/network/228908.NEQ379NEQ379; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
NEQ380 protein networkhttps://string-db.org/network/228908.NEQ380NEQ380.
NEQ381 protein networkhttps://string-db.org/network/228908.NEQ381NEQ381; Conserved hypothetical protein containing Radical SAM domain [Pyrococcus abyssi]; COG1180: Pyruvate-formate lyase-activating enzyme; IPR001989: Radical activating enzymes.
taw1 protein networkhttps://string-db.org/network/228908.NEQ382NEQ382; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG [...]
mre11 protein networkhttps://string-db.org/network/228908.NEQ383NEQ383; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the r [...]
NEQ384 protein networkhttps://string-db.org/network/228908.NEQ384NEQ384; RNA methyl transferase [Pyrococcus sp]; COG0565: rRNA methylase; IPR001537: tRNA/rRNA methyltransferase (SpoU).
NEQ385 protein networkhttps://string-db.org/network/228908.NEQ385NEQ385; Conserved hypothetical protein; IPR001179: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase).
NEQ386 protein networkhttps://string-db.org/network/228908.NEQ386NEQ386; Hypothetical protein; IPR001472: Bipartite nuclear localization signal.
NEQ387 protein networkhttps://string-db.org/network/228908.NEQ387NEQ387; ATP-dependent RNA helicase, EIF-4A FAMILY [Pyrococcus abyssi]; COG1111: ERCC4-like helicases; IPR001410: DEAD/DEAH box helicase; IPR002464: ATP-dependent helicase, DEAH-box; IPR001472: Bi [...]
rps5 protein networkhttps://string-db.org/network/228908.NEQ388NEQ388; With S4 and S12 plays an important role in translational accuracy.
tyrS protein networkhttps://string-db.org/network/228908.NEQ389NEQ389; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belong [...]
NEQ391 protein networkhttps://string-db.org/network/228908.NEQ391NEQ391.
eif5a protein networkhttps://string-db.org/network/228908.NEQ393NEQ393; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
NEQ395 protein networkhttps://string-db.org/network/228908.NEQ395NEQ395; Hypothetical protein; COG2219: Eukaryotic-type DNA primase, large subunit; COG3285: Predicted eukaryotic-type DNA primase; IPR001472: Bipartite nuclear localization signal.
NEQ396 protein networkhttps://string-db.org/network/228908.NEQ396NEQ396; Glu-tRNA amidotransferase [Methanococcus jannaschii] SPLIT; COG2511: Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain); IPR001472: Bipartite nuclear localization signa [...]
rpl21e protein networkhttps://string-db.org/network/228908.NEQ397NEQ397; LSU ribosomal protein L21E [Pyrococcus furiosus]; COG2139: Ribosomal protein L21E; IPR001147: Ribosomal protein L21E; IPR001472: Bipartite nuclear localization signal; Belongs to the euka [...]
NEQ398 protein networkhttps://string-db.org/network/228908.NEQ398NEQ398; Endonuclease III [Aquifex aeolicus] SPLIT see NEQ126a; COG0177: Predicted EndoIII-related endonuclease; IPR003265: HhH-GPD domain.
map protein networkhttps://string-db.org/network/228908.NEQ399NEQ399; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, [...]
NEQ401 protein networkhttps://string-db.org/network/228908.NEQ401NEQ401; Mg-chelatase subunit ChlI and Chld [Methanopyrus kandleri]; COG1239: Mg-chelatase subunit ChlI; IPR000619: Guanylate kinase; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR002078: S [...]
NEQ402 protein networkhttps://string-db.org/network/228908.NEQ402NEQ402; Deoxyhypusine synthase [Thermoplasma acidophilum]; COG1899: Deoxyhypusine synthase; IPR002773: Deoxyhypusine synthase.
NEQ403 protein networkhttps://string-db.org/network/228908.NEQ403NEQ403; Hypothetical protein; COG2304: Protein containing von Willebrand factor (vWF) type A domain; IPR002035: von Willebrand factor type A domain.
NEQ404 protein networkhttps://string-db.org/network/228908.NEQ404NEQ404; Hypothetical protein; IPR000504: RNA-binding region RNP-1 (RNA recognition motif).
NEQ405 protein networkhttps://string-db.org/network/228908.NEQ405NEQ405; Translation initiation factor eIF2-alpha [Methanopyrus kandleri]; COG1093: Translation initiation factor eIF2alpha; IPR003029: S1 RNA binding domain.
NEQ406 protein networkhttps://string-db.org/network/228908.NEQ406NEQ406; Hypothetical protein; COG0574: Phosphoenolpyruvate synthase/pyruvate phosphate dikinase.
NEQ407 protein networkhttps://string-db.org/network/228908.NEQ407NEQ407.
NEQ408 protein networkhttps://string-db.org/network/228908.NEQ408NEQ408.
NEQ409 protein networkhttps://string-db.org/network/228908.NEQ409NEQ409; Helicase-related protein [Pyrococcus furiosus]; COG1201: Lhr-like helicases; IPR001472: Bipartite nuclear localization signal.
NEQ410 protein networkhttps://string-db.org/network/228908.NEQ410NEQ410; ATPase subunit I [Clostridium thermocellum]; COG1269: Archaeal/vacuolar-type H+-ATPase subunit I; IPR002490: V-type ATPase 116kDa subunit family.
NEQ411 protein networkhttps://string-db.org/network/228908.NEQ411NEQ411; Hypothetical protein; COG1460: Uncharacterized ArCR.
NEQ412 protein networkhttps://string-db.org/network/228908.NEQ412NEQ412; Aminopeptidase [clostridium perfringens]; COG0260: Leucyl aminopeptidase; IPR000819: Cytosol aminopeptidase.
NEQ413 protein networkhttps://string-db.org/network/228908.NEQ413NEQ413.
NEQ414 protein networkhttps://string-db.org/network/228908.NEQ414NEQ414; Conserved hypothetical protein [Pyrococcus furiosus]; COG1750: Archaeal serine proteases; IPR001984: ATP-dependent serine proteases, Lon family; IPR000531: TonB-dependent receptor protein [...]
NEQ415 protein networkhttps://string-db.org/network/228908.NEQ415NEQ415; Hypothetical protein [Sulfolobus tokodaii]; IPR001680: G-protein beta WD-40 repeats.
NEQ416 protein networkhttps://string-db.org/network/228908.NEQ416NEQ416; Hypothetical protein; IPR000531: TonB-dependent receptor protein.
NEQ417 protein networkhttps://string-db.org/network/228908.NEQ417NEQ417; Glycyl-tRNA synthetase [Pyrococcus abyssi]; COG0423: Glycyl-tRNA synthetase, class II; IPR002106: Aminoacyl-transfer RNA synthetases class-II; IPR002314: tRNA synthetases, class-II (G, H, [...]
NEQ418 protein networkhttps://string-db.org/network/228908.NEQ418NEQ418; Hypothetical protein; IPR001472: Bipartite nuclear localization signal.
NEQ419 protein networkhttps://string-db.org/network/228908.NEQ419NEQ419; Hypothetical protein [Pyrococcus horikoshii].
polC protein networkhttps://string-db.org/network/228908.NEQ420NEQ420; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which [...]
NEQ421 protein networkhttps://string-db.org/network/228908.NEQ421NEQ421; Type II (general) secretory pathway (IISP) family protein [Methanosarcina acetivorans]; COG1136: ABC-type transport systems, involved in lipoprotein release, ATPase components; IPR001687: [...]
NEQ422 protein networkhttps://string-db.org/network/228908.NEQ422NEQ422; Dipthine synthase [Encephalitozoon cuniculi]; COG1798: Diphthamide biosynthesis methyltransferase DPH5; IPR000878: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
thiI protein networkhttps://string-db.org/network/228908.NEQ423NEQ423; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur t [...]
NEQ424 protein networkhttps://string-db.org/network/228908.NEQ424NEQ424; Conserved hypothetical protein [Methanothermobacter thermoautotrophicus]; COG1591: Holliday junction resolvase - archaeal type; IPR002732: Protein of unknown function DUF50.
NEQ425 protein networkhttps://string-db.org/network/228908.NEQ425NEQ425; Type IV secretion system protein [Methanosarcina acetivorans]; COG0630: Predicted ATPases involved in pili and flagella biosynthesis, VirB11 family; IPR001687: ATP/GTP-binding site motif [...]
radA protein networkhttps://string-db.org/network/228908.NEQ426NEQ426; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes [...]
rpoA2 protein networkhttps://string-db.org/network/228908.NEQ427NEQ427; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
NEQ428 protein networkhttps://string-db.org/network/228908.NEQ428NEQ428; Conserved hypothetical protein; COG1534: Predicted RNA-binding protein containing KH domain, possibly ribosomal protein; IPR001890: Uncharacterized protein family UPF0044.
NEQ429 protein networkhttps://string-db.org/network/228908.NEQ429NEQ429.
rfcL protein networkhttps://string-db.org/network/228908.NEQ430NEQ430; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily.
NEQ431 protein networkhttps://string-db.org/network/228908.NEQ431NEQ431; Conserved hypothetical protein [Pyrococcus furiosus]; COG1628: Uncharacterized ACR; IPR002802: Protein of unknown function DUF99; Belongs to the UPF0215 family.
NEQ432 protein networkhttps://string-db.org/network/228908.NEQ432NEQ432; Putative signal peptidase; COG0681: Signal peptidase I.
rpl3 protein networkhttps://string-db.org/network/228908.NEQ433NEQ433; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 [...]
NEQ434 protein networkhttps://string-db.org/network/228908.NEQ434NEQ434; Reverse gyrase [Pyrococcus horikoshii]; COG1110: Reverse gyrase; IPR001410: DEAD/DEAH box helicase; IPR001687: ATP/GTP-binding site motif A (P-loop).
NEQ435 protein networkhttps://string-db.org/network/228908.NEQ435NEQ435; Hypothetical protein [Archaeoglobus fulgidus]; COG2433: Uncharacterized ACR.
NEQ436 protein networkhttps://string-db.org/network/228908.NEQ436NEQ436; Protein translocase, subunit SECD [Methanococcus jannaschii]; COG0342: Preprotein translocase subunit SecD.
secF protein networkhttps://string-db.org/network/228908.NEQ437NEQ437; Involved in protein export.
NEQ438 protein networkhttps://string-db.org/network/228908.NEQ438NEQ438; Conserved hypothetical protein [Pyrococcus abyssi]; COG1293: Predicted RNA-binding protein homologous to eukaryotic snRNP.
NEQ440 protein networkhttps://string-db.org/network/228908.NEQ440NEQ440; Methyltransferase related protein [Methanothermobacter thermautotrophicus]; COG1041: Predicted DNA modification methylase; IPR000051: SAM (and some other nucleotide) binding motif; IPR002 [...]
NEQ441 protein networkhttps://string-db.org/network/228908.NEQ441NEQ441; Conserved hypothetical protein [Aquifex aeolicus]; COG2078: Uncharacterized ACR; IPR002733: Protein of unknown function DUF51.
NEQ442 protein networkhttps://string-db.org/network/228908.NEQ442NEQ442; Hypothetical protein; IPR001969: Eukaryotic and viral aspartic protease active site.
NEQ443 protein networkhttps://string-db.org/network/228908.NEQ443NEQ443; Hypothetical protein; COG0419: ATPase involved in DNA repair.
NEQ444 protein networkhttps://string-db.org/network/228908.NEQ444NEQ444.
NEQ445 protein networkhttps://string-db.org/network/228908.NEQ445NEQ445.
NEQ446 protein networkhttps://string-db.org/network/228908.NEQ446NEQ446; SSU ribosomal protein S9P [Pyrococcus furiosus]; COG0103: Ribosomal protein S9; IPR000754: Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
NEQ447 protein networkhttps://string-db.org/network/228908.NEQ447NEQ447.
NEQ448 protein networkhttps://string-db.org/network/228908.NEQ448NEQ448.
NEQ449 protein networkhttps://string-db.org/network/228908.NEQ449NEQ449; Hypothetical protein; COG1340: Uncharacterized archaeal coiled-coil domain.
rpl10e protein networkhttps://string-db.org/network/228908.NEQ450NEQ450; L10e ribosomal protein [Archaeoglobus fulgidus]; COG0197: Ribosomal protein L16/L10E; IPR001197: Ribosomal protein L10E; Belongs to the universal ribosomal protein uL16 family.
amzA protein networkhttps://string-db.org/network/228908.NEQ451NEQ451; Probable zinc metalloprotease whose natural substrate is unknown.
NEQ452 protein networkhttps://string-db.org/network/228908.NEQ452NEQ452; DNA-directed RNA polymerase, subunit D [Pyrococcus abyssi]; COG0202: DNA-directed RNA polymerase alpha subunit/40 kD subunit; IPR001514: RNA polymerases D/30 to 40 Kd subunits.
NEQ453 protein networkhttps://string-db.org/network/228908.NEQ453NEQ453; Predicted transcriptional regulator [Methanopyrus kandeleri]; COG1719: Uncharacterized ACR.
truB protein networkhttps://string-db.org/network/228908.NEQ454NEQ454; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
NEQ455 protein networkhttps://string-db.org/network/228908.NEQ455NEQ455; Conserved hypothetical protein [Pyrococcus abyssi]; COG1784: Predicted membrane protein.
NEQ456 protein networkhttps://string-db.org/network/228908.NEQ456NEQ456; Deoxyribonuclease Tat D family [Acidianus ambivalens]; COG0084: Mg-dependent DNase; IPR001130: Uncharacterized protein family UPF0006.
metG protein networkhttps://string-db.org/network/228908.NEQ457NEQ457; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
NEQ458 protein networkhttps://string-db.org/network/228908.NEQ458NEQ458.
NEQ459 protein networkhttps://string-db.org/network/228908.NEQ459NEQ459; Glutaredoxin-like protein [Pyrococcus furiosus]; COG0526: Thiol-disulfide isomerase and thioredoxins; IPR000063: Thioredoxin.
NEQ460 protein networkhttps://string-db.org/network/228908.NEQ460NEQ460; Predicted serine/threonine protein kinase [Methanopyrus kandleri]; COG1718: Predicted serine/threonine protein kinases; IPR000687: RIO1/ZK632.3/MJ0444 family; IPR001245: Tyrosine kinase c [...]
ppa protein networkhttps://string-db.org/network/228908.NEQ461NEQ461; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
NEQ462 protein networkhttps://string-db.org/network/228908.NEQ462NEQ462.
NEQ463 protein networkhttps://string-db.org/network/228908.NEQ463NEQ463; Conserved hypothetical GTP binding protein [Sulfolobus solfataricus]; COG0012: Predicted GTPase; IPR000765: GTP1/OBG family; IPR001687: ATP/GTP-binding site motif A (P-loop).
NEQ464 protein networkhttps://string-db.org/network/228908.NEQ464NEQ464; RIO1-like serine/threonine protein kinase [Methanopyrus kandleri]; COG0478: Predicted serine/threonine protein kinases; IPR000687: RIO1/ZK632.3/MJ0444 family; IPR001245: Tyrosine kinase c [...]
rnj protein networkhttps://string-db.org/network/228908.NEQ466NEQ466; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. [...]
rps13 protein networkhttps://string-db.org/network/228908.NEQ467NEQ467; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit [...]
NEQ468 protein networkhttps://string-db.org/network/228908.NEQ468NEQ468.
rps8e protein networkhttps://string-db.org/network/228908.NEQ469NEQ469; SSU ribosomal protein S8E [Archaeoglobus fulgidus]; COG2007: Ribosomal protein S8E; IPR001047: Ribosomal protein S8E; IPR001472: Bipartite nuclear localization signal.
NEQ470 protein networkhttps://string-db.org/network/228908.NEQ470NEQ470.
NEQ471 protein networkhttps://string-db.org/network/228908.NEQ471NEQ471.
NEQ472 protein networkhttps://string-db.org/network/228908.NEQ472NEQ472; Conserved hypothetical protein [Methanothermobacter thermoautotrophicus]; COG2129: Predicted phosphoesterases, related to the Icc protein; IPR000934: Serine/threonine specific protein pho [...]
ftsZ-2 protein networkhttps://string-db.org/network/228908.NEQ473NEQ473; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location [...]
NEQ474 protein networkhttps://string-db.org/network/228908.NEQ474NEQ474.
NEQ475 protein networkhttps://string-db.org/network/228908.NEQ475NEQ475; Cell division control protein 48 [Pyrococcus furiosus]; COG0464: ATPases of the AAA+ class; IPR003338: Amino-terminal subdomain, VAT-Nn; IPR001687: ATP/GTP-binding site motif A (P-loop); [...]
NEQ476 protein networkhttps://string-db.org/network/228908.NEQ476NEQ476.
NEQ477 protein networkhttps://string-db.org/network/228908.NEQ477NEQ477.
rps4e protein networkhttps://string-db.org/network/228908.NEQ478NEQ478; Ribosomal protein S4 [Methanothermobacter thermautotrophicus]; COG1471: Ribosomal protein S4E; IPR000876: Ribosomal protein S4E; IPR002942: S4 domain.
NEQ479 protein networkhttps://string-db.org/network/228908.NEQ479NEQ479; phenylalanyl-tRNA synthetase beta-chain [Pyrococcus furiosus]; COG0072: Phenylalanyl-tRNA synthetase beta subunit.
rps19 protein networkhttps://string-db.org/network/228908.NEQ480NEQ480; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rps3 protein networkhttps://string-db.org/network/228908.NEQ481NEQ481; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
tfe protein networkhttps://string-db.org/network/228908.NEQ482NEQ482; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-bo [...]
NEQ483 protein networkhttps://string-db.org/network/228908.NEQ483NEQ483.
NEQ484 protein networkhttps://string-db.org/network/228908.NEQ484NEQ484.
NEQ485 protein networkhttps://string-db.org/network/228908.NEQ485NEQ485; Hypothetical protein; COG1196: Chromosome segregation ATPases.
NEQ486 protein networkhttps://string-db.org/network/228908.NEQ486NEQ486; Sodium/Calcium exchanger protein [Oceanobacilus iheyensis]; COG0530: Ca2+/Na+ antiporter; IPR002613: Sodium/calcium exchanger protein.
rps15 protein networkhttps://string-db.org/network/228908.NEQ487NEQ487; Ribosomal protein S15P/S13E [Methanopyrus kandleri]; COG0184: Ribosomal protein S15P/S13E; IPR000589: Ribosomal protein S15.
rpl18e protein networkhttps://string-db.org/network/228908.NEQ489NEQ489; LSU ribosomal protein L18E [Sulfolobus solfataricus]; COG1727: Ribosomal protein L18E; IPR000531: TonB-dependent receptor protein; IPR001196: Ribosomal protein L15; IPR001472: Bipartite n [...]
NEQ490 protein networkhttps://string-db.org/network/228908.NEQ490NEQ490; Hypothetical protein; COG0500: SAM-dependent methyltransferases; IPR000051: SAM (and some other nucleotide) binding motif; IPR000504: RNA-binding region RNP-1 (RNA recognition motif).
NEQ491 protein networkhttps://string-db.org/network/228908.NEQ491NEQ491; Thioredoxin reductase [Sulfolobus tokodaii]; COG0492: Thioredoxin reductase; IPR000759: Adrenodoxin reductase; IPR000103: Pyridine nucleotide-disulphide oxidoreductase class-II; IPR001687 [...]
NEQ492 protein networkhttps://string-db.org/network/228908.NEQ492NEQ492.
kae1 protein networkhttps://string-db.org/network/228908.NEQ493NEQ493; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the [...]
NEQ494 protein networkhttps://string-db.org/network/228908.NEQ494NEQ494; Conserved hypothetical protein containing Radical SAM domain [Sulfolobus tokodaii]; COG1180: Pyruvate-formate lyase-activating enzyme.
NEQ495 protein networkhttps://string-db.org/network/228908.NEQ495NEQ495; Conserved hypothetical protein [Pyrococcus horikoshii]; COG1444: Predicted P-loop ATPase fused to an acetyltransferase; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR001472: Bipart [...]
NEQ497 protein networkhttps://string-db.org/network/228908.NEQ497NEQ497.
infB protein networkhttps://string-db.org/network/228908.NEQ498NEQ498; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
NEQ499 protein networkhttps://string-db.org/network/228908.NEQ499NEQ499.
NEQ500 protein networkhttps://string-db.org/network/228908.NEQ500NEQ500.
NEQ501 protein networkhttps://string-db.org/network/228908.NEQ501NEQ501; Probable metal transporter; COG0598: Mg2+ and Co2+ transporters.
NEQ502 protein networkhttps://string-db.org/network/228908.NEQ502NEQ502; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
NEQ503 protein networkhttps://string-db.org/network/228908.NEQ503NEQ503; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
NEQ504 protein networkhttps://string-db.org/network/228908.NEQ504NEQ504.
NEQ505 protein networkhttps://string-db.org/network/228908.NEQ505NEQ505; Phenylalanyl-tRNA synthetase alpha subunit [Sulfolobus solfataricus]; COG0016: Phenylalanyl-tRNA synthetase alpha subunit; IPR002319: Phenylalanyl-tRNA synthetase; IPR001472: Bipartite nu [...]
NEQ506 protein networkhttps://string-db.org/network/228908.NEQ506NEQ506; Conserved hypothetical protein [Sulfolobus solfataricus]; COG1293: Predicted RNA-binding protein homologous to eukaryotic snRNP.
rpoH protein networkhttps://string-db.org/network/228908.NEQ507NEQ507; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polyme [...]
rps2 protein networkhttps://string-db.org/network/228908.NEQ508NEQ508; 30S ribosomal protein S2 [Pyrococcus abyssi]; COG0052: Ribosomal protein S2; IPR001865: Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
lig protein networkhttps://string-db.org/network/228908.NEQ509NEQ509; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
NEQ510 protein networkhttps://string-db.org/network/228908.NEQ510NEQ510; Hypothetical protein; COG1175: ABC-type sugar transport systems, permease components.
NEQ511 protein networkhttps://string-db.org/network/228908.NEQ511NEQ511; Peptidase family M20/M25/M40 [Pyrococcus horikoshii]; COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; IPR002933: Peptidase family M20/M [...]
NEQ512 protein networkhttps://string-db.org/network/228908.NEQ512NEQ512; Conserved hypothetical protein [Methanosarcina acetivorans]; COG0433: Predicted ATPase; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR001472: Bipartite nuclear localization signal.
NEQ513 protein networkhttps://string-db.org/network/228908.NEQ513NEQ513.
NEQ514 protein networkhttps://string-db.org/network/228908.NEQ514NEQ514.
NEQ515 protein networkhttps://string-db.org/network/228908.NEQ515NEQ515; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- an [...]
NEQ516 protein networkhttps://string-db.org/network/228908.NEQ516NEQ516.
eif6 protein networkhttps://string-db.org/network/228908.NEQ517NEQ517; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
NEQ518 protein networkhttps://string-db.org/network/228908.NEQ518NEQ518.
NEQ519 protein networkhttps://string-db.org/network/228908.NEQ519NEQ519; HIT protein [Methanococcus jannaschii]; COG0537: Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; IPR001310: HIT (Histidine triad) family.
NEQ520 protein networkhttps://string-db.org/network/228908.NEQ520NEQ520.
NEQ521 protein networkhttps://string-db.org/network/228908.NEQ521NEQ521; Protease subunit of the proteasome [Methanopyrus kandleri]; COG0638: Proteasome protease subunit; IPR001353: Multispecific proteases of the proteasome.
NEQ522 protein networkhttps://string-db.org/network/228908.NEQ522NEQ522; Conserved hypothetical protein [Methanococcus jannaschii]; COG0116: Predicted N6-adenine-specific DNA methylases; IPR002052: N-6 Adenine-specific DNA methylase; IPR002296: N6 adenine-spec [...]
NEQ523 protein networkhttps://string-db.org/network/228908.NEQ523NEQ523; Conserved hypothetical protein [Pyrococcus abyssi]; COG0037: Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; IPR000541: Uncharacterized protein family UPF002 [...]
NEQ524 protein networkhttps://string-db.org/network/228908.NEQ524NEQ524; Conserved hypothetical protein [Methanopyrus kandleri]; COG1500: Uncharacterized ACR; IPR002140: Uncharacterized protein family UPF0023; IPR001472: Bipartite nuclear localization signal.
NEQ525 protein networkhttps://string-db.org/network/228908.NEQ525NEQ525; N-type ATP pyrophosphatase superfamily [Pyrococcus furiosus]; COG0175: 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes; IPR00250 [...]
NEQ526 protein networkhttps://string-db.org/network/228908.NEQ526NEQ526; Hypothetical protein [Thermoplasma volcanium]; COG1549: Queuine tRNA-ribosyltransferases, contain PUA domain.
NEQ527 protein networkhttps://string-db.org/network/228908.NEQ527NEQ527; 495aa long conserved hypothetical protein [Sulfolobus tokoda..; COG0433: Predicted ATPase; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR002789: Domain of unknown function DUF87.
NEQ528 protein networkhttps://string-db.org/network/228908.NEQ528NEQ528; DNA directed DNA polymerase [Thermococcus sp] SPLIT see NEQ068; COG0417: DNA polymerase elongation subunit (family B); IPR002203: Protein splicing (intein); IPR002064: DNA-directed DNA po [...]
NEQ529 protein networkhttps://string-db.org/network/228908.NEQ529NEQ529.
rpl32e protein networkhttps://string-db.org/network/228908.NEQ530NEQ530; LSU ribosomal protein L32E [Pyrococcus abyssi]; COG1717: Ribosomal protein L32E; IPR001515: Ribosomal protein L32e; IPR001472: Bipartite nuclear localization signal; Belongs to the eukary [...]
NEQ531 protein networkhttps://string-db.org/network/228908.NEQ531NEQ531; Mechanosensitive ion channel [Nostoc sp]; COG0668: Small-conductance mechanosensitive channel; PS50317: ILE_RICH; IPR001880: Uncharacterized protein family UPF0003.
NEQ532 protein networkhttps://string-db.org/network/228908.NEQ532NEQ532.
NEQ533 protein networkhttps://string-db.org/network/228908.NEQ533NEQ533.
NEQ534 protein networkhttps://string-db.org/network/228908.NEQ534NEQ534; Conserved hypothetical protein [Pyrococcus horikoshii]; COG1318: Predicted transcriptional regulators.
aspS protein networkhttps://string-db.org/network/228908.NEQ535NEQ535; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp).
NEQ536 protein networkhttps://string-db.org/network/228908.NEQ536NEQ536; Putative RNA methylase [Pyrococcus furiosus]; COG0144: tRNA and rRNA cytosine-C5-methylases; IPR000051: SAM (and some other nucleotide) binding motif; IPR001678: NOL1/NOP2/sun family.
pcn protein networkhttps://string-db.org/network/228908.NEQ537NEQ537; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed repl [...]
NEQ538 protein networkhttps://string-db.org/network/228908.NEQ538NEQ538; Putative acetylpolyamine aminohydrolase [Pyrobaculum aerophilum]; COG0123: Deacetylases, including yeast histone deacetylase and acetoin utilization protein; IPR000286: Histone deacetylas [...]
NEQ539 protein networkhttps://string-db.org/network/228908.NEQ539NEQ539.
spt5 protein networkhttps://string-db.org/network/228908.NEQ540NEQ540; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
NEQ541 protein networkhttps://string-db.org/network/228908.NEQ541NEQ541.
top6A protein networkhttps://string-db.org/network/228908.NEQ542NEQ542; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.
fusA protein networkhttps://string-db.org/network/228908.NEQ543NEQ543; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocation [...]
NEQ544 protein networkhttps://string-db.org/network/228908.NEQ544NEQ544; Predicted membrane-associated Zn-dependent protease [Methanopyrus kandleri]; COG0750: Predicted membrane-associated Zn-dependent proteases 1; IPR000130: Neutral zinc metallopeptidases, zi [...]
NEQ545 protein networkhttps://string-db.org/network/228908.NEQ545NEQ545.
rpl1 protein networkhttps://string-db.org/network/228908.NEQ546NEQ546; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
NEQ547 protein networkhttps://string-db.org/network/228908.NEQ547NEQ547; alanyl-tRNA synthetase; COG0013: Alanyl-tRNA synthetase; IPR002318: Alanyl-tRNA synthetase.
rps24e protein networkhttps://string-db.org/network/228908.NEQ548NEQ548; SSU ribosomal protein S24E [Methanococcus jannashii]; COG2004: Ribosomal protein S24E; IPR001976: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
NEQ549 protein networkhttps://string-db.org/network/228908.NEQ549NEQ549; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and [...]
NEQ550 protein networkhttps://string-db.org/network/228908.NEQ550NEQ550.