Organism Overview: Bacillus subtilis 168


 
dnaA protein networkhttps://string-db.org/network/224308.BSU00010Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically doub [...]
dnaN protein networkhttps://string-db.org/network/224308.BSU00020DNA polymerase III (beta subunit); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-load [...]
yaaA protein networkhttps://string-db.org/network/224308.BSU00030Putative RNA binding protein; May assist in the assembly of the 50S subunit.
recF protein networkhttps://string-db.org/network/224308.BSU00040DNA repair and genetic recombination factor; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-st [...]
yaaB protein networkhttps://string-db.org/network/224308.BSU00050Conserved hypothetical protein; Regulates the biosynthesis of the extracellular matrix and the biofilm formation. May act as an enhancer of biofilm gene expression. Acts in parallel to the pathwa [...]
gyrB protein networkhttps://string-db.org/network/224308.BSU00060DNA gyrase (subunit B); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
gyrA protein networkhttps://string-db.org/network/224308.BSU00070DNA gyrase (subunit A); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
yaaC protein networkhttps://string-db.org/network/224308.BSU00080Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
guaB protein networkhttps://string-db.org/network/224308.BSU00090Inosine-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis o [...]
dacA protein networkhttps://string-db.org/network/224308.BSU00100D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Belongs to the peptidase S11 family.
pdxS protein networkhttps://string-db.org/network/224308.BSU00110Glutamine amidotransferase for pyridoxal phosphate synthesis; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The am [...]
pdxT protein networkhttps://string-db.org/network/224308.BSU00120Glutamine amidotransferase for pyridoxal phosphate synthesis; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting a [...]
serS protein networkhttps://string-db.org/network/224308.BSU00130seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
dck protein networkhttps://string-db.org/network/224308.BSU00140Deoxyadenosine/deoxycytidine kinase; Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward [...]
dgk protein networkhttps://string-db.org/network/224308.BSU00150Deoxyguanosine kinase; Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only [...]
yaaH protein networkhttps://string-db.org/network/224308.BSU00160Spore peptidoglycan hydrolase; N-acetylglucosaminidase involved in cortex peptidoglycan degradation during germination. Cleaves only partially degraded spore peptidoglycans. Recognizes muramic ac [...]
yaaI protein networkhttps://string-db.org/network/224308.BSU00170Putative isochorismatase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the isochorismatase fa [...]
tadA protein networkhttps://string-db.org/network/224308.BSU00180tRNA specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
dnaX protein networkhttps://string-db.org/network/224308.BSU00190DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.
yaaK protein networkhttps://string-db.org/network/224308.BSU00200DNA binding protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
recR protein networkhttps://string-db.org/network/224308.BSU00210DNA repair and recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
yaaL protein networkhttps://string-db.org/network/224308.BSU00220Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
bofA protein networkhttps://string-db.org/network/224308.BSU00230Inhibitor of the pro-sigma(K) processing machinery; Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB- processing [...]
csfB protein networkhttps://string-db.org/network/224308.BSU00240Forespore-specific anti-sigma factor; An anti-sigma-G factor, prevents premature activation of sigma-G factor in the forespore; overexpression leads to 1000-fold reduction in spore formation, spo [...]
xpaC protein networkhttps://string-db.org/network/224308.BSU00250Putative phosphatase; In double copy it causes aberrant cell morphology, filamentation and inhibits sporulation. Hydrolyzes 5-bromo-4- chloroindolyl phosphate.
yaaN protein networkhttps://string-db.org/network/224308.BSU00260Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12533473; Belongs to the TelA family.
yaaO protein networkhttps://string-db.org/network/224308.BSU00270Putative decarboxylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
tmk protein networkhttps://string-db.org/network/224308.BSU00280Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
yaaQ protein networkhttps://string-db.org/network/224308.BSU00290Conserved hypothetical protein; Binds cyclic di-AMP (c-di-AMP) and is probably involved in c- di-AMP-mediated signaling pathways. In vitro, can also bind cyclic GMP- AMP (3'3'-cGAMP), with lower [...]
yaaR protein networkhttps://string-db.org/network/224308.BSU00300Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
holB protein networkhttps://string-db.org/network/224308.BSU00310DNA polymerase III delta' subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.
yaaT protein networkhttps://string-db.org/network/224308.BSU00320Conserved hypothetical protein; Essential for the phosphorelay during initiation of sporulation. May control the level of phosphorylated spo0A through spo0E activity during sporulation.
dnaH protein networkhttps://string-db.org/network/224308.BSU00330Subunit of the DNA replication complex; Involved in initiation control of chromosome replication.
yabB protein networkhttps://string-db.org/network/224308.BSU00340Putative methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yazA protein networkhttps://string-db.org/network/224308.BSU00350Putative UvrC-Intron-type (URI) endonuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to th [...]
rsmI protein networkhttps://string-db.org/network/224308.BSU00360Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
abrB protein networkhttps://string-db.org/network/224308.BSU00370Transcriptional regulator for transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onse [...]
metS protein networkhttps://string-db.org/network/224308.BSU00380methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the [...]
yabD protein networkhttps://string-db.org/network/224308.BSU00390Metal-dependent DNase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.
yabE protein networkhttps://string-db.org/network/224308.BSU00400Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
rnmV protein networkhttps://string-db.org/network/224308.BSU00410Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. Releases 5'-p [...]
ksgA protein networkhttps://string-db.org/network/224308.BSU00420Dimethyladenosine 16S ribosomal RNA transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S part [...]
yabG protein networkhttps://string-db.org/network/224308.BSU00430Sporulation-specific protease; Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross-linking of coat proteins like GerQ.
veg protein networkhttps://string-db.org/network/224308.BSU00440Conserved hypothetical protein; Stimulates biofilm formation via transcriptional activation of extracellular matrix genes. Acts by repressing SinR activity, independently of the SinI, SlrA and Sl [...]
sspF protein networkhttps://string-db.org/network/224308.BSU00450Small acid-soluble spore protein (alpha/beta-type SASP); May play some important role in either sporulation or the dormant spore.
ispE protein networkhttps://string-db.org/network/224308.BSU004604-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
purR protein networkhttps://string-db.org/network/224308.BSU00470Transcriptional regulator of the purine biosynthesis operon; Controls the transcription of the pur operon for purine biosynthetic genes, binds to the control region of the operon. DNA binding is [...]
yabJ protein networkhttps://string-db.org/network/224308.BSU00480Aminoacrylate/iminopropionate hydrolase/deaminase; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water [...]
spoVG protein networkhttps://string-db.org/network/224308.BSU00490Regulator required for spore cortex synthesis (stage V sporulation); Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation. Belongs [...]
gcaD protein networkhttps://string-db.org/network/224308.BSU00500Bifunctional glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acety [...]
prs protein networkhttps://string-db.org/network/224308.BSU00510Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to [...]
ctc protein networkhttps://string-db.org/network/224308.BSU00520Ribosomal protein Ctc, binding 5S RNA; Not required for exponential growth; probably functions in vegetatively growing cells, maybe required for accurate translation under stress conditions.
pth protein networkhttps://string-db.org/network/224308.BSU00530peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
fin protein networkhttps://string-db.org/network/224308.BSU00540Protein required for the switch from F to G during sporulation (anti sigma F); An anti-sigma factor for sporulation specific sigma-F factor, by antagonizing sigma-F it allows the switch to sigma- [...]
mfd protein networkhttps://string-db.org/network/224308.BSU00550Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated tr [...]
spoVT protein networkhttps://string-db.org/network/224308.BSU00560Transcriptional regulator; Transcriptional factor that regulates positively or negatively the expression of a large number of forespore-specific sigma G-dependent genes. May provide a mechanism o [...]
yabM protein networkhttps://string-db.org/network/224308.BSU00570Putative exporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yabN protein networkhttps://string-db.org/network/224308.BSU00580Putative fusion methylase and nucleotide pyrophosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzy [...]
hslR protein networkhttps://string-db.org/network/224308.BSU00590Ribosomal RNA binding protein involved in 50S recycling; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; factor.
yabP protein networkhttps://string-db.org/network/224308.BSU00600Spore protein involved in the shaping of the spore coat; Required for sporulation.
yabQ protein networkhttps://string-db.org/network/224308.BSU00610Membrane protein of the forespore; Required for sporulation. Plays an important role in cortex and coat formation.
divIC protein networkhttps://string-db.org/network/224308.BSU00620Cell-division initiation protein; Required for vegetative and sporulation septum formation. Required for the activation of genes expressed under the control of the sporulation transcription facto [...]
yabR protein networkhttps://string-db.org/network/224308.BSU00630Putative RNA degradation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs [...]
spoIIE protein networkhttps://string-db.org/network/224308.BSU00640SpoIIAA-phosphate serine phosphatase; Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells. Activates SpoIIAA by dephosphorylation.
yabS protein networkhttps://string-db.org/network/224308.BSU00650Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yabT protein networkhttps://string-db.org/network/224308.BSU00660Putative serine/threonine-protein kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
tilS protein networkhttps://string-db.org/network/224308.BSU00670tRNAile lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is c [...]
hprT protein networkhttps://string-db.org/network/224308.BSU00680Hypoxanthine-guanine phosphoribosyltransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
ftsH protein networkhttps://string-db.org/network/224308.BSU00690Cell-division protein and general stress protein (class III heat-shock); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the [...]
coaX protein networkhttps://string-db.org/network/224308.BSU00700Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. Cannot utilize a phosphoryl donor other than ATP; Belongs to the type III pantothenat [...]
hslO protein networkhttps://string-db.org/network/224308.BSU00710Disulfide bond chaperone (heat shock protein HSP33); Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays a [...]
yacD protein networkhttps://string-db.org/network/224308.BSU00720Putative protein secretion PrsA homolog; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
cysK protein networkhttps://string-db.org/network/224308.BSU00730Cysteine synthase; Catalyzes the conversion of O-acetylserine to cysteine. Also acts as a sensor of cysteine availability in the signal transduction pathway modulating CymR activity. When cystein [...]
pabB protein networkhttps://string-db.org/network/224308.BSU007404-amino-4-deoxychorismate synthase (para-aminobenzoate synthase); Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p- am [...]
pabA protein networkhttps://string-db.org/network/224308.BSU007504-amino-4-deoxychorismate synthase; Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p- aminobenzoate (PABA) and tetrahy [...]
pabC protein networkhttps://string-db.org/network/224308.BSU007604-amino-4-deoxychorismate pyruvate-lyase; Involved in the biosynthesis of p-aminobenzoate (PABA), a precursor of tetrahydrofolate. Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) a [...]
folP protein networkhttps://string-db.org/network/224308.BSU00770Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate [...]
folB protein networkhttps://string-db.org/network/224308.BSU00780Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
folK protein networkhttps://string-db.org/network/224308.BSU007907,8-dihydro-6-hydroxymethylpterin pyrophosphokinase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the HPPK family.
yazB protein networkhttps://string-db.org/network/224308.BSU00800Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
dusB protein networkhttps://string-db.org/network/224308.BSU00810tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines [...]
lysS protein networkhttps://string-db.org/network/224308.BSU00820lysyl-tRNA synthetase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family.
ctsR protein networkhttps://string-db.org/network/224308.BSU00830Transcriptional regulator; Controls the expression of the cellular protein quality control genes clpC, clpE and clpP, as well as mcsA and mcsB. Acts as a repressor of these class III stress genes [...]
mcsA protein networkhttps://string-db.org/network/224308.BSU00840Activator of protein kinase McsB; Activates the phosphorylation activity of the protein- arginine kinase McsB. Is required for the delocalization of competence proteins from the cell poles.
mcsB protein networkhttps://string-db.org/network/224308.BSU00850Protein tyrosine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system, where it is involved in regula [...]
clpC protein networkhttps://string-db.org/network/224308.BSU00860Class III stress response-related ATPase, AAA+ superfamily; Competence gene repressor; required for cell growth at high temperature. Negative regulator of comK expression. May interact with MecA [...]
radA protein networkhttps://string-db.org/network/224308.BSU00870DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand trans [...]
disA protein networkhttps://string-db.org/network/224308.BSU00880Diadenylate cyclase; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. Forms globular foci that rapidly scan along the chromosomes during s [...]
yacL protein networkhttps://string-db.org/network/224308.BSU00890Putative membrane protein; An RNase; In the central section; belongs to the PINc/VapC protein family.
ispD protein networkhttps://string-db.org/network/224308.BSU009002-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, nonmevalonate isoprenoid pathway; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythr [...]
ispF protein networkhttps://string-db.org/network/224308.BSU009102-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
gltX protein networkhttps://string-db.org/network/224308.BSU00920glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
cysE protein networkhttps://string-db.org/network/224308.BSU00930Serine acetyltransferase; Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS).
cysS protein networkhttps://string-db.org/network/224308.BSU00940cysteinyl-tRNA synthetase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.
mrnC protein networkhttps://string-db.org/network/224308.BSU00950Ribonuclease for 23S RNA maturation; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rn [...]
rlmB protein networkhttps://string-db.org/network/224308.BSU0096023S rRNA methyltransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the class IV-like SAM-binding methyltrans [...]
yacP protein networkhttps://string-db.org/network/224308.BSU00970Putative ribonuclease with PIN and NYN domains; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
sigH protein networkhttps://string-db.org/network/224308.BSU00980RNA polymerase sigma-30 factor (sigma(H)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor [...]
rpmGB protein networkhttps://string-db.org/network/224308.BSU00990Ribosomal protein L33; Plays a role in sporulation at high temperatures.
secE protein networkhttps://string-db.org/network/224308.BSU01000Preprotein translocase subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
nusG protein networkhttps://string-db.org/network/224308.BSU01010Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. Stimulates RNA polymerase pausing at U107 and U144 in the trp leader. NusG-stimula [...]
rplK protein networkhttps://string-db.org/network/224308.BSU01020Ribosomal protein L11 (BL11); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
rplA protein networkhttps://string-db.org/network/224308.BSU01030Ribosomal protein L1 (BL1); Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. Belongs to the universal ribosomal protein uL1 family [...]
rplJ protein networkhttps://string-db.org/network/224308.BSU01040Ribosomal protein L10 (BL5); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors (such as IF-2, EF-Tu, EF-G and RF3).
rplL protein networkhttps://string-db.org/network/224308.BSU01050Ribosomal protein L12 (BL9); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
ybxB protein networkhttps://string-db.org/network/224308.BSU01060Ribosomal RNA methyltransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the methyltransferase superfamily.
rpoB protein networkhttps://string-db.org/network/224308.BSU01070RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoC protein networkhttps://string-db.org/network/224308.BSU01080RNA polymerase (beta' subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplGB protein networkhttps://string-db.org/network/224308.BSU01090Alternative ribosomal protein L7A; RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA, but also in box C/D and box C'/D' sRNAs. Belongs to the eukaryotic ribosomal prot [...]
rpsL protein networkhttps://string-db.org/network/224308.BSU01100Ribosomal protein S12 (BS12); With S4 and S5 plays an important role in translational accuracy.
rpsG protein networkhttps://string-db.org/network/224308.BSU01110Ribosomal protein S7 (BS7); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit in [...]
fusA protein networkhttps://string-db.org/network/224308.BSU01120Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
tufA protein networkhttps://string-db.org/network/224308.BSU01130Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
ybaC protein networkhttps://string-db.org/network/224308.BSU01140Putative proline iminopeptidase; Probable aminopeptidase.
rpsJ protein networkhttps://string-db.org/network/224308.BSU01150Ribosomal protein S10 (BS13); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rplC protein networkhttps://string-db.org/network/224308.BSU01160Ribosomal protein L3 (BL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity). Strongly s [...]
rplD protein networkhttps://string-db.org/network/224308.BSU01170Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes mul [...]
rplW protein networkhttps://string-db.org/network/224308.BSU01180Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking [...]
rplB protein networkhttps://string-db.org/network/224308.BSU01190Ribosomal protein L2 (BL2); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. I [...]
rpsS protein networkhttps://string-db.org/network/224308.BSU01200Ribosomal protein S19 (BS19); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplV protein networkhttps://string-db.org/network/224308.BSU01210Ribosomal protein L22 (BL17); This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of [...]
rpsC protein networkhttps://string-db.org/network/224308.BSU01220Ribosomal protein S3 (BS3); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplP protein networkhttps://string-db.org/network/224308.BSU01230Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpmC protein networkhttps://string-db.org/network/224308.BSU01240Ribosomal protein L29; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
rpsQ protein networkhttps://string-db.org/network/224308.BSU01250Ribosomal protein S17 (BS16); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rplNA protein networkhttps://string-db.org/network/224308.BSU01260Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rplX protein networkhttps://string-db.org/network/224308.BSU01270Ribosomal protein L24 (BL23); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. Has also been isolated as a [...]
rplE protein networkhttps://string-db.org/network/224308.BSU01280Ribosomal protein L5 (BL6); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberan [...]
rpsNA protein networkhttps://string-db.org/network/224308.BSU01290Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity). The m [...]
rpsH protein networkhttps://string-db.org/network/224308.BSU01300Ribosomal protein S8 (BS8); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs t [...]
rplF protein networkhttps://string-db.org/network/224308.BSU01310Ribosomal protein L6 (BL8); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the [...]
rplR protein networkhttps://string-db.org/network/224308.BSU01320Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
rpsE protein networkhttps://string-db.org/network/224308.BSU01330Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; many suppressors of streptomycin-dependent mutants of protein S12 are found in this protein, some but not [...]
rpmD protein networkhttps://string-db.org/network/224308.BSU01340Ribosomal protein L30 (BL27); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type s: structure.
rplO protein networkhttps://string-db.org/network/224308.BSU01350Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
secY protein networkhttps://string-db.org/network/224308.BSU01360Preprotein translocase subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the fr [...]
adk protein networkhttps://string-db.org/network/224308.BSU01370Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
mapA protein networkhttps://string-db.org/network/224308.BSU01380Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
ybzG protein networkhttps://string-db.org/network/224308.BSU01389Putative ribosomal protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
infA protein networkhttps://string-db.org/network/224308.BSU01390Initiation factor IF-I; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) s [...]
rpmJ protein networkhttps://string-db.org/network/224308.BSU01400Ribosomal protein L36 (ribosomal protein B); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.
rpsM protein networkhttps://string-db.org/network/224308.BSU01410Ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of [...]
rpsK protein networkhttps://string-db.org/network/224308.BSU01420Ribosomal protein S11 (BS11); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Be [...]
rpoA protein networkhttps://string-db.org/network/224308.BSU01430RNA polymerase (alpha subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplQ protein networkhttps://string-db.org/network/224308.BSU01440Ribosomal protein L17 (BL15); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
ecfA protein networkhttps://string-db.org/network/224308.BSU01450Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transpor [...]
ecfAB protein networkhttps://string-db.org/network/224308.BSU01460Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transpor [...]
ecfT protein networkhttps://string-db.org/network/224308.BSU01470Component of the influx ECF transporters; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the [...]
truA protein networkhttps://string-db.org/network/224308.BSU01480Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
rplM protein networkhttps://string-db.org/network/224308.BSU01490Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of [...]
rpsI protein networkhttps://string-db.org/network/224308.BSU01500Ribosomal protein S9; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type s: structure.
ybaJ protein networkhttps://string-db.org/network/224308.BSU01510Putative methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the [...]
ybaK protein networkhttps://string-db.org/network/224308.BSU01520Putative alkylated deoxynucleotide triphosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: put [...]
cwlD protein networkhttps://string-db.org/network/224308.BSU01530N-acetylmuramoyl-L-alanine amidase; Cleaves the peptide side chain from the N-acetylmuramic acid residues in peptidoglycan. This is a step in the formation of muramic delta-lactam residues in spo [...]
salA protein networkhttps://string-db.org/network/224308.BSU01540Mrp family regulator; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
gerD protein networkhttps://string-db.org/network/224308.BSU01550Lipoprotein with a role in spores' rapid response to nutrient germinants; May be involved in fructose recognition during germination.
kbaA protein networkhttps://string-db.org/network/224308.BSU01560Inner membrane protein involved in activation of the KinB signaling pathway to sporulation; Involved in the activation of the KinB signaling pathway of sporulation.
ybaN protein networkhttps://string-db.org/network/224308.BSU01570Polysaccharide deacetylase involved in sporulation; Necessary to maintain spores after the late stage of sporulation. Might be involved in cortex formation.
ybaR protein networkhttps://string-db.org/network/224308.BSU01580Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type m: membrane component.
ybaS protein networkhttps://string-db.org/network/224308.BSU01590Putative sodium dependent transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter [...]
ybbA protein networkhttps://string-db.org/network/224308.BSU01600Putative iron-chelator esterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
feuC protein networkhttps://string-db.org/network/224308.BSU01610Iron-uptake protein; Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane.
feuB protein networkhttps://string-db.org/network/224308.BSU01620Iron-uptake protein; Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane.
feuA protein networkhttps://string-db.org/network/224308.BSU01630Iron hydroxamate-binding lipoprotein; Involved in the uptake of iron. Belongs to the bacterial solute-binding protein 8 family.
btr protein networkhttps://string-db.org/network/224308.BSU01640HTH-type transcriptional activator Btr; In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system. Acts by binding directly to a con [...]
ybbC protein networkhttps://string-db.org/network/224308.BSU01650Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
nagZ protein networkhttps://string-db.org/network/224308.BSU01660N-acetylglucosaminidase lipoprotein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, gi [...]
amiE protein networkhttps://string-db.org/network/224308.BSU01670Amidase hydrolyzing N-acetylmuramyl-L-Ala bond of MurNAc peptides; Involved in muropeptide recycling. Hydrolyzes the amide bond between N-acetylmuramic acid (MurNAc) and the L-alanine residue of [...]
ybbF protein networkhttps://string-db.org/network/224308.BSU01680Putative PTS system EIIBC component ybbF; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylati [...]
ybbH protein networkhttps://string-db.org/network/224308.BSU01690Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
murQ protein networkhttps://string-db.org/network/224308.BSU01700D-lactyl ether N-acetylmuramic-6-phosphate acid etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.
ybbJ protein networkhttps://string-db.org/network/224308.BSU01710Putative acyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ybbK protein networkhttps://string-db.org/network/224308.BSU01720Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
sigW protein networkhttps://string-db.org/network/224308.BSU01730RNA polymerase ECF(extracytoplasmic function)-type sigma factor W; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then rel [...]
rsiW protein networkhttps://string-db.org/network/224308.BSU01740anti-sigma(W) factor; The anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-W (SigW). Holds SigW, its cognate ECF sigma factor, in an inactive form until released by regula [...]
ybbP protein networkhttps://string-db.org/network/224308.BSU01750Putative enzyme with DAC domain protein; One of 3 paralogous diadenylate cyclases (DAC) in this bacteria, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP) (Probable). [...]
ybbR protein networkhttps://string-db.org/network/224308.BSU01760Conserved hypothetical protein; Upon coexpression in E.coli stimulates the diadenylate cyclase activity of CdaA about 20-fold. In B.subtilis c-di-AMP is a second messenger that mediates growth, D [...]
glmM protein networkhttps://string-db.org/network/224308.BSU01770Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity). Glucosamine-1-phosphate is used for cell wall biosynthesis (Probable); B [...]
glmS protein networkhttps://string-db.org/network/224308.BSU01780L-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
alkA protein networkhttps://string-db.org/network/224308.BSU01800DNA-3-methyladenine glycosylase; Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Catalyzes the hydrolysis of the deoxyribose N-glycosidic bond to exc [...]
adaA protein networkhttps://string-db.org/network/224308.BSU01810methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC/XylS family); Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs [...]
adaB protein networkhttps://string-db.org/network/224308.BSU01820O6-methylguanine-DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated n [...]
ndhF protein networkhttps://string-db.org/network/224308.BSU01830Putative NADH dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the complex I subun [...]
ybcC protein networkhttps://string-db.org/network/224308.BSU01845Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0753 family.
ybcF protein networkhttps://string-db.org/network/224308.BSU01860Putative carbonic anhydrase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to th [...]
ybcH protein networkhttps://string-db.org/network/224308.BSU01870Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ybcI protein networkhttps://string-db.org/network/224308.BSU01880Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ybzH protein networkhttps://string-db.org/network/224308.BSU01889Putative transcriptional regulator (ArsR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
ybcL protein networkhttps://string-db.org/network/224308.BSU01890Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ybcM protein networkhttps://string-db.org/network/224308.BSU01900Putative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
skfA protein networkhttps://string-db.org/network/224308.BSU01910Sporulation killing factor A; Produces a 26-residue extracellular sporulation filling factor (SKF) that induces the lysis of other B.subtilis cells that have not entered the sporulation pathway, [...]
skfB protein networkhttps://string-db.org/network/224308.BSU01920Synthesis of sporulation killing factor A; Catalyzes the formation of the thioether bond required for production of the sporulation killing factor (SKF) from SkfA. Forms the cysteine-methionine t [...]
skfC protein networkhttps://string-db.org/network/224308.BSU01935Sporulation killing factor biosynthesis and export; Required for production of the bacteriocin SkfA.
skfE protein networkhttps://string-db.org/network/224308.BSU01950Sporulation killing factor biosynthesis and export; Probably part of the ABC transporter SkfEF involved in the export of the bacteriocin SKF. Probably responsible for energy coupling to the trans [...]
skfF protein networkhttps://string-db.org/network/224308.BSU01960Sporulation killing factor biosynthesis and export; Probably part of the ABC transporter SkfEF involved in the export of the bacteriocin SKF. Probably responsible for the translocation of bacteri [...]
skfG protein networkhttps://string-db.org/network/224308.BSU01970Sporulation killing factor biosynthesis and export; Required for production of the bacteriocin SkfA.
skfH protein networkhttps://string-db.org/network/224308.BSU01980Sibling killing effect; Required for production of the bacteriocin SkfA.
ybdG protein networkhttps://string-db.org/network/224308.BSU01990Putative hydrolase/transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ybdJ protein networkhttps://string-db.org/network/224308.BSU02000Two-component response regulator [YbdK]; Member of the two-component regulatory system YbdK/YbdJ.
ybdK protein networkhttps://string-db.org/network/224308.BSU02010Two-component sensor histidine kinase [YbdJ]; Member of the two-component regulatory system YbdK/YbdJ. Probably activates YbdJ by phosphorylation.
ybzI protein networkhttps://string-db.org/network/224308.BSU02019Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ybdM protein networkhttps://string-db.org/network/224308.BSU02030Putative protein kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ybdN protein networkhttps://string-db.org/network/224308.BSU02040Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.
ybdO protein networkhttps://string-db.org/network/224308.BSU02050Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.
ybxG protein networkhttps://string-db.org/network/224308.BSU02060Putative amino acid permease; Probable amino-acid or metabolite transport protein; Belongs to the amino acid-polyamine-organocation (APC) superfamily.
csgA protein networkhttps://string-db.org/network/224308.BSU02070Sporulation-specific SASP protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
ybxH protein networkhttps://string-db.org/network/224308.BSU02080Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ybxI protein networkhttps://string-db.org/network/224308.BSU02090Exported beta-lactamase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
cypC protein networkhttps://string-db.org/network/224308.BSU02100Fatty acid beta-hydroxylating cytochrome P450; Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide; Belongs to the cytochrome P450 family.
ybyB protein networkhttps://string-db.org/network/224308.BSU02110Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ybeC protein networkhttps://string-db.org/network/224308.BSU02120Putative H+/amino acid transporter; Uptake of an yet unknown amino-acid with the concomitant import of a proton; Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3. [...]
glpQA protein networkhttps://string-db.org/network/224308.BSU02130Glycerophosphoryl diester phosphodiesterase; Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols.
glpT protein networkhttps://string-db.org/network/224308.BSU02140Glycerol-3-phosphate permease; Responsible for glycerol-3-phosphate uptake; Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
ybeF protein networkhttps://string-db.org/network/224308.BSU02150Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ybfA protein networkhttps://string-db.org/network/224308.BSU02160Conserved hypothetical protein; Putative DNA-binding acetyltransferase.
ybfB protein networkhttps://string-db.org/network/224308.BSU02170Putative carboxylate transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ybfE protein networkhttps://string-db.org/network/224308.BSU02180Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ybfF protein networkhttps://string-db.org/network/224308.BSU02190Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ybfG protein networkhttps://string-db.org/network/224308.BSU02200Putative pepdidoglycan binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
ybfH protein networkhttps://string-db.org/network/224308.BSU02210Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ybfI protein networkhttps://string-db.org/network/224308.BSU02220Putative transcriptional regulator (AraC/XylS family, cupin family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product [...]
purT protein networkhttps://string-db.org/network/224308.BSU02230Phosphoribosylglycinamide formyltransferase 2; Catalyzes two reactions: the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR; the second, [...]
mpr protein networkhttps://string-db.org/network/224308.BSU02240Extracellular glutamyl-endopeptidase; Evidence 1c: Function experimentally demonstrated in the studied genus; Product type e: enzyme; Belongs to the peptidase S1B family.
ybfJ protein networkhttps://string-db.org/network/224308.BSU02250Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
ybfK protein networkhttps://string-db.org/network/224308.BSU02260Carboxylesterase NP; Shows carboxylesterase activity in vitro.
pssA protein networkhttps://string-db.org/network/224308.BSU02270Phosphatidylserine synthase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
ybfM protein networkhttps://string-db.org/network/224308.BSU02280Putative membrane phosphatase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
psd protein networkhttps://string-db.org/network/224308.BSU02290Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-B subf [...]
ybfN protein networkhttps://string-db.org/network/224308.BSU02300Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ybfO protein networkhttps://string-db.org/network/224308.BSU02310Putative exported hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ybfP protein networkhttps://string-db.org/network/224308.BSU02320Putative transcriptional regulator (AraC/XylS family); Probable transcriptional regulator.
ybfQ protein networkhttps://string-db.org/network/224308.BSU02330Putative enzyme with rhodanese domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the UPF01 [...]
gltP protein networkhttps://string-db.org/network/224308.BSU02340Proton/glutamate symport protein; Catalyzes the proton-dependent, binding-protein-independent transport of glutamate and aspartate; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS [...]
gamP protein networkhttps://string-db.org/network/224308.BSU02350Phosphotransferase system (PTS) glucosamine-specific enzyme IICBA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport s [...]
nagBB protein networkhttps://string-db.org/network/224308.BSU02360Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glu [...]
ybgA protein networkhttps://string-db.org/network/224308.BSU02370Putative transcriptional regulator (GntR family); Transcriptional repressor of genes involved in glucosamine transport and utilization. Represses the expression of the gamAP operon by binding to [...]
ybgB protein networkhttps://string-db.org/network/224308.BSU02380Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 12897008.
ilvE protein networkhttps://string-db.org/network/224308.BSU02390Ketomethiobutyrate-branched-chain/aromatic amino acid aminotransferase; Transaminates branched-chain amino acids and ketoglutarate. Involved in the final step of the methionine regeneration pathw [...]
ybgF protein networkhttps://string-db.org/network/224308.BSU02400Putative aminoacid permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ybgG protein networkhttps://string-db.org/network/224308.BSU02410Homocysteine methylase using (R,S)AdoMet; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.
glnT protein networkhttps://string-db.org/network/224308.BSU02420Glutamine transporter; Probably functions as a sodium/glutamine symporter for glutamine uptake; Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
glsA protein networkhttps://string-db.org/network/224308.BSU02430Glutaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
glnJ protein networkhttps://string-db.org/network/224308.BSU02440Two-component sensor histidine kinase [GlnL] for glutamine degradation; Member of the two-component regulatory system GlnK/GlnL that positively regulates the expression of the glsA-glnT operon in [...]
glnL protein networkhttps://string-db.org/network/224308.BSU02450Two-component response regulator [GlnJ] for glutamine utilisation; Member of the two-component regulatory system GlnL/GlnK that positively regulates the expression of the glsA-glnT operon in resp [...]
ycbC protein networkhttps://string-db.org/network/224308.BSU024605-dehydro-4-deoxyglucarate dehydratase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the DapA family.
ycbD protein networkhttps://string-db.org/network/224308.BSU024702,5-dioxovalerate dehydrogenase (alpha-ketoglutaric semialdehyde dehydrogenase); Catalyzes the NAD(P)(+)-dependent oxidation of alpha- ketoglutaric semialdehyde (alphaKGSA) to alpha-ketoglutarate [...]
gudP protein networkhttps://string-db.org/network/224308.BSU02480Glucarate transporter; Uptake of D-glucarate; Belongs to the major facilitator superfamily. Phthalate permease family.
gudD protein networkhttps://string-db.org/network/224308.BSU02490Glucarate dehydratase; Catalyzes the dehydration of glucarate to 5-keto-4-deoxy-D- glucarate (5-kdGluc); Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.
ycbG protein networkhttps://string-db.org/network/224308.BSU02500Transcriptional regulator (GntR family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
garD protein networkhttps://string-db.org/network/224308.BSU02510D-galactarate dehydratase; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate.
ycbJ protein networkhttps://string-db.org/network/224308.BSU02520Putative phosphotransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the aminoglycoside [...]
rtpA protein networkhttps://string-db.org/network/224308.BSU02530anti-TRAP regulator; By forming a complex with tryptophan-activated TRAP, and masking its RNA binding site, it inhibits TRAP's RNA binding ability, thereby abolishing TRAP regulation of gene expr [...]
ycbK protein networkhttps://string-db.org/network/224308.BSU02540Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
ycbL protein networkhttps://string-db.org/network/224308.BSU02550Two-component response regulator [YcbM]; Member of the two-component regulatory system YcbM/YcbL.
ycbM protein networkhttps://string-db.org/network/224308.BSU02560Two-component sensor histidine kinase [YcbL]; Member of the two-component regulatory system YcbM/YcbL. Probably activates YcbL by phosphorylation.
ycbN protein networkhttps://string-db.org/network/224308.BSU02570Putative ABC efflux transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; [...]
ycbO protein networkhttps://string-db.org/network/224308.BSU02580Putative Na+-driven exporter or maturation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putativ [...]
ycbP protein networkhttps://string-db.org/network/224308.BSU02590Putative inner integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
cwlJ protein networkhttps://string-db.org/network/224308.BSU02600Cell wall hydrolase; Probable spore cortex-lytic enzyme involved in the depolymerization of cortex peptidoglycan during germination.
ycbR protein networkhttps://string-db.org/network/224308.BSU02610Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yczK protein networkhttps://string-db.org/network/224308.BSU02619Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
phoD protein networkhttps://string-db.org/network/224308.BSU02620Alkaline phosphatase D; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme.
tatAD protein networkhttps://string-db.org/network/224308.BSU02630Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- argi [...]
tatCD protein networkhttps://string-db.org/network/224308.BSU02640Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- argi [...]
pcp protein networkhttps://string-db.org/network/224308.BSU02650Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
ycbU protein networkhttps://string-db.org/network/224308.BSU02660Putative cysteine desulfurase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
lmrB protein networkhttps://string-db.org/network/224308.BSU02670Efflux transporter; Proton-dependent transporter. May mediate the efflux of lincomycin; Belongs to the major facilitator superfamily. EmrB family.
lmrA protein networkhttps://string-db.org/network/224308.BSU02680Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons.
ansZ protein networkhttps://string-db.org/network/224308.BSU02690L-asparaginase 2 (putative lipoprotein); Catalyzes the conversion of L-asparagine to L-aspartate and ammonium.
estA protein networkhttps://string-db.org/network/224308.BSU02700Secreted alkaliphilic lipase; Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups. Belongs to the AB hydrolase superfamily.
yczC protein networkhttps://string-db.org/network/224308.BSU02710Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yccF protein networkhttps://string-db.org/network/224308.BSU02720Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
natK protein networkhttps://string-db.org/network/224308.BSU02730Two-component sensor histidine kinase [NatR]; Member of the two-component regulatory system NatK/NatR that positively regulates the expression of the natAB operon. Potentially phosphorylates NatR [...]
natR protein networkhttps://string-db.org/network/224308.BSU02740Two-component response regulator [NatK]; Member of the two-component regulatory system NatK/NatR that positively regulates the expression of the natAB operon. Acts by binding directly to the prom [...]
natA protein networkhttps://string-db.org/network/224308.BSU02750Na+ ABC efflux transporter (ATP-binding protein); Part of an ABC transporter that catalyzes ATP-dependent electrogenic sodium extrusion; Belongs to the ABC transporter superfamily.
natB protein networkhttps://string-db.org/network/224308.BSU02760Na+ ABC efflux transporter (permease); Part of an ABC transporter that catalyzes ATP-dependent electrogenic sodium extrusion.
yccK protein networkhttps://string-db.org/network/224308.BSU02770Putative ion channel associated enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the aldo [...]
ycdA protein networkhttps://string-db.org/network/224308.BSU02780Lipoprotein involved in swarming behaviour; Evidence 1b: Function experimentally demonstrated in the studied species; Product type lp: lipoprotein.
ycdB protein networkhttps://string-db.org/network/224308.BSU02790Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To B.subtilis YcdC.
ycdC protein networkhttps://string-db.org/network/224308.BSU02800Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To B.subtilis YcdB.
cwlK protein networkhttps://string-db.org/network/224308.BSU02810Murein L,D:-endopeptidase; Cleaves the linkage of the L-alanine-D-glutamic acid of B.subtilis cell wall; Belongs to the peptidase M15C family.
rapJ protein networkhttps://string-db.org/network/224308.BSU02820Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
ycdF protein networkhttps://string-db.org/network/224308.BSU02830Putative glucose 1-dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs [...]
ycdG protein networkhttps://string-db.org/network/224308.BSU02840Putative oligo-carbohydrate hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
znuA protein networkhttps://string-db.org/network/224308.BSU02850Zn(II)-binding lipoprotein; Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). ZnuABC-mediated zinc transport is required for comF expression and compete [...]
znuC protein networkhttps://string-db.org/network/224308.BSU02860Zn(II) transporter (ATP-binding protein); Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). Responsible for energy coupling to the transport system (By [...]
znuB protein networkhttps://string-db.org/network/224308.BSU02870High affinity Zn(II) ABC transporter (permease); Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). Responsible for the translocation of the substrate ac [...]
yceB protein networkhttps://string-db.org/network/224308.BSU02880Putative monooxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; To bacterial alkanal monooxygenase [...]
yceC protein networkhttps://string-db.org/network/224308.BSU02890Putative stress adaptation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belong [...]
yceD protein networkhttps://string-db.org/network/224308.BSU02900Putative stress adaptation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
yceE protein networkhttps://string-db.org/network/224308.BSU02910Putative stress adaptation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belong [...]
yceF protein networkhttps://string-db.org/network/224308.BSU02920Putative stress adaptation transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporte [...]
yceG protein networkhttps://string-db.org/network/224308.BSU02930Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yceH protein networkhttps://string-db.org/network/224308.BSU02940Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the TelA family.
naiP protein networkhttps://string-db.org/network/224308.BSU02950Niacin permease; Probably involved in the uptake of amidated and deamidated forms of niacin. Increases the growth rate of E.coli that is unable to make niacin de novo; confers increased sensitivi [...]
yceJ protein networkhttps://string-db.org/network/224308.BSU02960Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yceK protein networkhttps://string-db.org/network/224308.BSU02970Putative transcriptional regulator (ArsR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
opuAA protein networkhttps://string-db.org/network/224308.BSU02980Glycine betaine ABC transporter (ATP-binding protein); Involved in a multicomponent binding-protein-dependent transport system for glycine betaine. Probably responsible for energy coupling to the [...]
opuAB protein networkhttps://string-db.org/network/224308.BSU02990Glycine betaine ABC transporter (permease); Involved in a multicomponent binding-protein-dependent transport system for glycine betaine; probably responsible for the translocation of the substrat [...]
opuAC protein networkhttps://string-db.org/network/224308.BSU03000Glycine betaine ABC transporter (glycine betaine-binding lipoprotein); Involved in a multicomponent binding-protein-dependent transport system for glycine betaine.
amhX protein networkhttps://string-db.org/network/224308.BSU03010Amidohydrolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the peptidase M20 family.
ycgA protein networkhttps://string-db.org/network/224308.BSU03020Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ycgB protein networkhttps://string-db.org/network/224308.BSU03030Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
amyE protein networkhttps://string-db.org/network/224308.BSU03040Alpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family.
ldh protein networkhttps://string-db.org/network/224308.BSU03050L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
lctP protein networkhttps://string-db.org/network/224308.BSU03060L-lactate permease; May play a role in L-lactate transport.
mdr protein networkhttps://string-db.org/network/224308.BSU03070Multidrug-efflux transporter; Confers resistance to puromycin, tosufloxacin and norfloxacin.
ycgE protein networkhttps://string-db.org/network/224308.BSU03080Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
ycgF protein networkhttps://string-db.org/network/224308.BSU03090Putative aminoacid export permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ycgG protein networkhttps://string-db.org/network/224308.BSU03100Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DcsA family.
ycgH protein networkhttps://string-db.org/network/224308.BSU03110Putative amino acid transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ycgI protein networkhttps://string-db.org/network/224308.BSU03120Putative methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
nadE protein networkhttps://string-db.org/network/224308.BSU03130Ammonium-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
tmrB protein networkhttps://string-db.org/network/224308.BSU03140ATP-binding tunicamycin resistance protein; Involved in the resistance to tunicamycin. Binds ATP.
aroK protein networkhttps://string-db.org/network/224308.BSU03150Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
ycgJ protein networkhttps://string-db.org/network/224308.BSU03160Putative methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the [...]
ycgK protein networkhttps://string-db.org/network/224308.BSU03170Putative transcriptional regulator (LysR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belong [...]
cah protein networkhttps://string-db.org/network/224308.BSU03180Promiscuous acetyl xylan esterase-cephalosporin C deacetylase; Esterase that removed acetyl groups from a number of O- acetylated small substrates, such as acetylated xylose, short xylooligosacch [...]
ycgL protein networkhttps://string-db.org/network/224308.BSU03190Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
putB protein networkhttps://string-db.org/network/224308.BSU03200Proline oxidase; Converts proline to delta-1-pyrroline-5-carboxylate. Important for the use of proline as a sole carbon and energy source or a sole nitrogen source.
putC protein networkhttps://string-db.org/network/224308.BSU032101-pyrroline-5-carboxylate dehydrogenase; Important for the use of proline as a sole carbon and energy source or a sole nitrogen source.
putP protein networkhttps://string-db.org/network/224308.BSU03220Proline permease; Catalyzes the high-affinity uptake of extracellular proline. Important for the use of proline as a sole carbon and energy source or a sole nitrogen source.
putR protein networkhttps://string-db.org/network/224308.BSU03230Transcriptional activator of proline degradation operon; Activates transcription of the putBCP operon. Requires proline as a coactivator.
ycgQ protein networkhttps://string-db.org/network/224308.BSU03240Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ycgR protein networkhttps://string-db.org/network/224308.BSU03250Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ycgS protein networkhttps://string-db.org/network/224308.BSU03260Putative aromatic hydrocarbon hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; B [...]
ycgT protein networkhttps://string-db.org/network/224308.BSU03270Putative ferredoxin/thioredoxin reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
nasF protein networkhttps://string-db.org/network/224308.BSU03280uroporphyrin-III C-methyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the precorrin methyltransferase family.
nasE protein networkhttps://string-db.org/network/224308.BSU03290Assimilatory nitrite reductase subunit; Required for nitrite assimilation. Required for activity of the reductase (By similarity).
nasD protein networkhttps://string-db.org/network/224308.BSU03300Assimilatory nitrite reductase subunit; Required for nitrite assimilation.
nasC protein networkhttps://string-db.org/network/224308.BSU03310Assimilatory nitrate reductase (catalytic subunit); Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
nasB protein networkhttps://string-db.org/network/224308.BSU03320Assimilatory nitrate reductase (electron transfer subunit NasB); Required for nitrate assimilation.
nasA protein networkhttps://string-db.org/network/224308.BSU03330Putative nitrate transporter; May function as a nitrate transporter.
folEB protein networkhttps://string-db.org/network/224308.BSU03340GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate. Belongs to the GTP cyclohydrolase IV family.
yciB protein networkhttps://string-db.org/network/224308.BSU03350Putative metal uptake system lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transpor [...]
yczL protein networkhttps://string-db.org/network/224308.BSU03359Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
zinT protein networkhttps://string-db.org/network/224308.BSU03360Zinc metallochaperone with NTPase activity; May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc.
yckA protein networkhttps://string-db.org/network/224308.BSU03370Putative ABC transporter (permease); Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs [...]
yckB protein networkhttps://string-db.org/network/224308.BSU03380Putative ABC transporter (binding lipoprotein); Probably part of a binding-protein-dependent transport system; Belongs to the bacterial solute-binding protein 3 family.
yckC protein networkhttps://string-db.org/network/224308.BSU03390Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yckD protein networkhttps://string-db.org/network/224308.BSU03400Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
bglC protein networkhttps://string-db.org/network/224308.BSU03410Aryl-phospho-beta-d-glucosidase; Is able to catalyze the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D-glucopyranoside (MUG-P), phosphoarbutin and phos [...]
nin protein networkhttps://string-db.org/network/224308.BSU03420Inhibitor of the DNA degrading activity of NucA (competence); Plays a role in the competence of cells to be transformed. It inhibits the activity of the DNA-entry nuclease.
nucA protein networkhttps://string-db.org/network/224308.BSU03430Endonuclease; By degrading DNA that enters the cell, plays a role in the competence of cells to be transformed. Degrades both double-stranded, linear and covalently closed circular DNA.
tlpC protein networkhttps://string-db.org/network/224308.BSU03440Methyl-accepting chemotaxis protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; receptor.
hxlB protein networkhttps://string-db.org/network/224308.BSU034506-phospho-3-hexuloisomerase (PHI); Catalyzes the isomerization between 3-hexulose 6-phosphate and fructose 6-phosphate. Together with HxlA, may act as a formaldehyde detoxification system.
hxlA protein networkhttps://string-db.org/network/224308.BSU034603-hexulose-6-phosphate synthase (HPS); Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate. Together with HxlB, may act as a formaldehyde detoxific [...]
hxlR protein networkhttps://string-db.org/network/224308.BSU03470Positive regulator of hxlAB expression; Positive regulator of hxlAB expression.
srfAA protein networkhttps://string-db.org/network/224308.BSU03480Surfactin synthetase; This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu, Glu, Asp and Val. Activation sites for these AA consist of individual domains.
srfAB protein networkhttps://string-db.org/network/224308.BSU03490Surfactin synthetase; This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu, Glu, Asp and Val. Activation sites for these AA consist of individual domains.
comS protein networkhttps://string-db.org/network/224308.BSU03500Regulator of genetic competence; Required for the development of competence.
srfAC protein networkhttps://string-db.org/network/224308.BSU03510Surfactin synthetase; Probably activates a leucine.
srfAD protein networkhttps://string-db.org/network/224308.BSU03520Surfactin synthetase; Probable thioesterase involved in the biosynthesis of surfactin; Belongs to the thioesterase family.
ycxA protein networkhttps://string-db.org/network/224308.BSU03530Putative carboxylate permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ycxB protein networkhttps://string-db.org/network/224308.BSU03540Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ycxC protein networkhttps://string-db.org/network/224308.BSU03550Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ycxD protein networkhttps://string-db.org/network/224308.BSU03560Putative PLP-dependent transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
yczE protein networkhttps://string-db.org/network/224308.BSU03580N-terminal part of 4'-phosphopantetheinyl transferase (Surfactin synthetase-activating enzyme); Evidence 7: Gene remnant; Product type e: enzyme.
tcyC protein networkhttps://string-db.org/network/224308.BSU03590Cystine ABC transporter (ATP-binding protein); Part of the ABC transporter complex TcyABC involved in L- cystine import. Responsible for energy coupling to the transport system (Probable).
tcyB protein networkhttps://string-db.org/network/224308.BSU03600Cystine ABC transporter (permease); Part of the ABC transporter complex TcyABC involved in L- cystine import. Probably responsible for the translocation of the substrate across the membrane (Prob [...]
tcyA protein networkhttps://string-db.org/network/224308.BSU03610Cystine ABC transporter (substrate-binding lipoprotein); Part of the ABC transporter complex TcyABC involved in L- cystine import.
bsdA protein networkhttps://string-db.org/network/224308.BSU03620HTH-type transcriptional regulator BsdA (LysR family); Could be a positive regulator of bsdBCD expression in response to salicylic acid.
bsdB protein networkhttps://string-db.org/network/224308.BSU03630Phenolic acid decarboxylase subunit BsdB; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. Flavin prenyltransf [...]
bsdC protein networkhttps://string-db.org/network/224308.BSU03640Phenolic acid decarboxylase subunit BsdC; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. Phenolic acid decar [...]
bsdD protein networkhttps://string-db.org/network/224308.BSU03651Phenolic acid decarboxylase subunit BsdD; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions, however the precise [...]
yclD protein networkhttps://string-db.org/network/224308.BSU03652Putative FMN-binding enzyme subunit; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yclE protein networkhttps://string-db.org/network/224308.BSU03660Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the AB hydr [...]
dtpT protein networkhttps://string-db.org/network/224308.BSU03670Di-tripeptide-proton ABC symporter; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t: transporter.
yclG protein networkhttps://string-db.org/network/224308.BSU03680Putative uronase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yczF protein networkhttps://string-db.org/network/224308.BSU03690Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
gerKA protein networkhttps://string-db.org/network/224308.BSU03700Spore germination receptor subunit; Involved in the germination response to the combination of glucose, fructose, L-asparagine, and KCl; Belongs to the GerABKA family.
gerKC protein networkhttps://string-db.org/network/224308.BSU03710Spore germination receptor subunit; Involved in the germination response to the combination of glucose, fructose, L-asparagine, and KCl; Belongs to the GerABKC lipoprotein family.
gerKB protein networkhttps://string-db.org/network/224308.BSU03720Spore germination receptor subunit; Involved in the germination response to the combination of glucose, fructose, L-asparagine, and KCl; Belongs to the amino acid-polyamine-organocation (APC) sup [...]
yclH protein networkhttps://string-db.org/network/224308.BSU03730Putative ABC transporter (ATPase component); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative trans [...]
yclI protein networkhttps://string-db.org/network/224308.BSU03740Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yclJ protein networkhttps://string-db.org/network/224308.BSU03750Two-component response regulator [YclK]; Could be member of the two-component regulatory system YclK/YclJ.
yclK protein networkhttps://string-db.org/network/224308.BSU03760Two-component sensor histidine kinase [YclJ]; Could be member of the two-component regulatory system YclK/YclJ. Potentially phosphorylates YclJ.
rapC protein networkhttps://string-db.org/network/224308.BSU03770Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the RAP family.
phrC protein networkhttps://string-db.org/network/224308.BSU03780Phosphatase RapC inhibitor; Inhibitor of the activity of phosphatase RapC; Belongs to the phr family.
yczM protein networkhttps://string-db.org/network/224308.BSU03788Putative type I toxin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type f: factor.
yczN protein networkhttps://string-db.org/network/224308.BSU03789Putative spore and germination protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; factor.
yclM protein networkhttps://string-db.org/network/224308.BSU03790Aspartate kinase III; Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway lea [...]
yclN protein networkhttps://string-db.org/network/224308.BSU03800Putative iron-siderophore ABC transporter (permease); Part of the ABC transporter complex YclNOPQ involved in uptake of ferric-petrobactin. Petrobactin is a photoreactive 3,4- catecholate siderop [...]
yclO protein networkhttps://string-db.org/network/224308.BSU03810Putative iron-siderophore ABC transporter (permease); Part of the ABC transporter complex YclNOPQ involved in uptake of ferric-petrobactin. Petrobactin is a photoreactive 3,4- catecholate siderop [...]
yclP protein networkhttps://string-db.org/network/224308.BSU03820Putative iron-siderophore ABC transporter (ATP-binding protein); Part of the ABC transporter complex YclNOPQ involved in uptake of ferric-petrobactin. Petrobactin is a photoreactive 3,4- catechol [...]
yclQ protein networkhttps://string-db.org/network/224308.BSU03830Putative iron-siderophore ABC transporter (binding lipoprotein); Part of the ABC transporter complex YclNOPQ involved in uptake of ferric-petrobactin. Petrobactin is a photoreactive 3,4- catechol [...]
ycnB protein networkhttps://string-db.org/network/224308.BSU03840Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ycnC protein networkhttps://string-db.org/network/224308.BSU03850Putative transcriptional regulator (TetR/AcrR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: puta [...]
nfrAB protein networkhttps://string-db.org/network/224308.BSU03860NADPH-FMN oxidoreductase (nitroreductase); Reduces FMNH(2) to FMN, with NADH or NADPH as reductant. It also reduces nitroaromatic compounds, quinones, chromates and azo dyes. It could supply the [...]
ycnE protein networkhttps://string-db.org/network/224308.BSU03870Conserved hypothetical protein; Putative monooxygenase that may contribute to the degradation of aromatic compounds; Belongs to the LsrG family.
yczG protein networkhttps://string-db.org/network/224308.BSU03880Putative transcriptional regulator (ArsR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
gabR protein networkhttps://string-db.org/network/224308.BSU03890Transcriptional regulator (GntR/MocR family) with PLP binding site; Activates the transcription of the gabTD operon. Is also a repressor of its own expression, both in the presence and absence of [...]
gabT protein networkhttps://string-db.org/network/224308.BSU039004-aminobutyrate aminotransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the class-III pyridoxal-phosphate-d [...]
gabD protein networkhttps://string-db.org/network/224308.BSU03910Succinate-semialdehyde dehydrogenase; Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate.
glcU protein networkhttps://string-db.org/network/224308.BSU03920Glucose uptake protein; Involved in the uptake of glucose.
gdh protein networkhttps://string-db.org/network/224308.BSU03930Glucose 1-dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
ycnI protein networkhttps://string-db.org/network/224308.BSU03940Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ycnJ protein networkhttps://string-db.org/network/224308.BSU03950Putative copper import protein; Involved in uptake of extracellular oxidized copper under copper-limiting conditions; In the N-terminal section; belongs to the CopC family.
ycnK protein networkhttps://string-db.org/network/224308.BSU03960Putative transcriptional regulator (DeoR family); May act as a negative transcriptional regulator of ycnJ in the presence of copper. May use copper as a corepressor.
ycnL protein networkhttps://string-db.org/network/224308.BSU03970Putative reductase or disulfide isomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
mtlA protein networkhttps://string-db.org/network/224308.BSU03981Phosphotransferase system (PTS) mannitol-specific enzyme IICB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport syste [...]
mtlF protein networkhttps://string-db.org/network/224308.BSU03982Phosphotransferase system (PTS) mannitol-specific enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system [...]
mtlD protein networkhttps://string-db.org/network/224308.BSU03990Mannitol-1-phosphate dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
ycsA protein networkhttps://string-db.org/network/224308.BSU04000Putative tartrate dehydrogenase; Has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso- tartrate to D-glycerate and catalyze [...]
sipU protein networkhttps://string-db.org/network/224308.BSU04010Type I signal peptidase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the peptidase S26 family.
yczH protein networkhttps://string-db.org/network/224308.BSU04020Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the dienela [...]
ycsD protein networkhttps://string-db.org/network/224308.BSU04030Putative hydroxyacyl-(acyl carrier protein) dehydratase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: pu [...]
yczO protein networkhttps://string-db.org/network/224308.BSU04039Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ycsE protein networkhttps://string-db.org/network/224308.BSU04040Putative phosphatase; Catalyzes the dephosphorylation of the riboflavin precursor 5-amino-6-(5-phospho-D-ribitylamino)uracil and of flavin mononucleotide (FMN) in vitro. To a lesser extent, may a [...]
ycsF protein networkhttps://string-db.org/network/224308.BSU04050Putative nitrogen-containing heterocycle degradation enzyme; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Belongs to [...]
ycsG protein networkhttps://string-db.org/network/224308.BSU04060Putative branched chain amino acids transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative t [...]
ycsI protein networkhttps://string-db.org/network/224308.BSU04070Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9334321; Belongs to the D-glutamate cyclase family.
kipI protein networkhttps://string-db.org/network/224308.BSU04080Putative inhibitor of the autophosphorylation reaction of KinA; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addi [...]
kipA protein networkhttps://string-db.org/network/224308.BSU04090Putative hydrolase subunit antagonist of KipI; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, counteracts [...]
kipR protein networkhttps://string-db.org/network/224308.BSU04100Transcriptional regulator (IclR family); Transcriptional repressor of the kip gene-containing operon.
lipC protein networkhttps://string-db.org/network/224308.BSU04110Spore coat phospholipase B; Lipase involved in spore germination. Belongs to the 'GDSL' lipolytic enzyme family.
yczI protein networkhttps://string-db.org/network/224308.BSU04120Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yczJ protein networkhttps://string-db.org/network/224308.BSU04130Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
pbpC protein networkhttps://string-db.org/network/224308.BSU04140Penicillin-binding lipoprotein 3; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type lp: lipoprotein.
ycsN protein networkhttps://string-db.org/network/224308.BSU04150Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the al [...]
mtlR protein networkhttps://string-db.org/network/224308.BSU04160Transcriptional regulator; Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol.
ydaB protein networkhttps://string-db.org/network/224308.BSU04170Putative acyl-CoA ligase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the A [...]
ydaC protein networkhttps://string-db.org/network/224308.BSU04180Putative methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the [...]
ydaD protein networkhttps://string-db.org/network/224308.BSU04190Putative dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ydaE protein networkhttps://string-db.org/network/224308.BSU04200Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10220166; Belongs to the D-lyxose ketol-isomerase family.
ydaF protein networkhttps://string-db.org/network/224308.BSU04210Putative ribosomal protein N-acetyltransferase; Putative N-acetyltransferase. May act on ribosomal proteins (Potential); Belongs to the acetyltransferase family.
ydaG protein networkhttps://string-db.org/network/224308.BSU04220Putative general stress protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
ydaH protein networkhttps://string-db.org/network/224308.BSU04230Putative integral inner membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane [...]
ydzA protein networkhttps://string-db.org/network/224308.BSU04240Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
lrpC protein networkhttps://string-db.org/network/224308.BSU04250Transcriptional regulator (Lrp/AsnC family); Transcriptional regulator with a possible role in regulation of amino acid metabolism. Plays a role in the growth phase transition.
topB protein networkhttps://string-db.org/network/224308.BSU04260DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand o [...]
ydaJ protein networkhttps://string-db.org/network/224308.BSU04270Putative glycosyl hydrolase lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
ydaK protein networkhttps://string-db.org/network/224308.BSU04280Putative membrane protein with diguanylate cyclase domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: [...]
ydaL protein networkhttps://string-db.org/network/224308.BSU04290Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydaM protein networkhttps://string-db.org/network/224308.BSU04300Putative glycosyltransferase associated to biofilm formation; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type p [...]
ydaN protein networkhttps://string-db.org/network/224308.BSU04310Putative regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
ydaO protein networkhttps://string-db.org/network/224308.BSU04320Putative metabolite transporter; High-affinity potassium transporter.
mutT protein networkhttps://string-db.org/network/224308.BSU04330Putative NTP pyrophosphohydrolase; May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo- dGTP) from DNA and the nucleo [...]
ydaP protein networkhttps://string-db.org/network/224308.BSU04340Putative enzyme with pyruvate as substrate; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme [...]
ydzK protein networkhttps://string-db.org/network/224308.BSU04359Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
mntH protein networkhttps://string-db.org/network/224308.BSU04360Manganese transporter; H(+)-stimulated, divalent metal cation uptake system. Involved in manganese uptake. Can probably also transport cadmium, cobalt, copper and zinc, but not iron. May be the p [...]
ydaS protein networkhttps://string-db.org/network/224308.BSU04370Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydaT protein networkhttps://string-db.org/network/224308.BSU04380Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydbA protein networkhttps://string-db.org/network/224308.BSU04390Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
gsiB protein networkhttps://string-db.org/network/224308.BSU04400General stress protein; Involved in an adaptive response to nutrient deprivation other than sporulation.
ydbB protein networkhttps://string-db.org/network/224308.BSU04410Putative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the SchB/CurC family.
ydbC protein networkhttps://string-db.org/network/224308.BSU04420Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydbD protein networkhttps://string-db.org/network/224308.BSU04430Putative manganese-containing catalase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the mang [...]
dctB protein networkhttps://string-db.org/network/224308.BSU04440C4-dicarboxylate binding protein; Part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. Responsible for growth on fumarate and succinate but not malate. Is not d [...]
dctS protein networkhttps://string-db.org/network/224308.BSU04450Two-component sensor histidine kinase; Member of the two-component regulatory system DctS/DctR. Probably activates DctR by phosphorylation (By similarity). Essential for expression of dctP.
dctR protein networkhttps://string-db.org/network/224308.BSU04460Two-component response regulator; Member of the two-component regulatory system DctS/DctR. Essential for expression of dctP.
dctP protein networkhttps://string-db.org/network/224308.BSU04470C4-dicarboxylate transport protein; Responsible for the transport of succinate and fumarate, but not malate, across the membrane.
ydbI protein networkhttps://string-db.org/network/224308.BSU04480Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ydbJ protein networkhttps://string-db.org/network/224308.BSU04490Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative tr [...]
ydbK protein networkhttps://string-db.org/network/224308.BSU04500Putative efflux ABC-transporter (permease component); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putat [...]
ydbL protein networkhttps://string-db.org/network/224308.BSU04510Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydbM protein networkhttps://string-db.org/network/224308.BSU04520Putative acyl-CoA dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs t [...]
fbpB protein networkhttps://string-db.org/network/224308.BSU04530Regulator of iron homeostasis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
fbpA protein networkhttps://string-db.org/network/224308.BSU04536Regulator of iron homeostasis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
ydbO protein networkhttps://string-db.org/network/224308.BSU04540Putative cation efflux system; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ydbP protein networkhttps://string-db.org/network/224308.BSU04550Putative thioredoxin or thiol-disulfide isomerase; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disul [...]
ddl protein networkhttps://string-db.org/network/224308.BSU04560D-alanyl-D-alanine ligase A; Cell wall formation.
murF protein networkhttps://string-db.org/network/224308.BSU04570UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapepti [...]
cshA protein networkhttps://string-db.org/network/224308.BSU04580ATP-dependent RNA helicase; The most abundant DEAD-box RNA helicase. An ATP-dependent RNA helicase with RNA-dependent ATPase activity. May work in conjunction with the cold shock proteins to ensu [...]
ydbS protein networkhttps://string-db.org/network/224308.BSU04590Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydbT protein networkhttps://string-db.org/network/224308.BSU04600Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydcA protein networkhttps://string-db.org/network/224308.BSU04610Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15616571, 15849754, 16850406.
acpS protein networkhttps://string-db.org/network/224308.BSU04620Holo-acyl carrier protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of fatty acid acyl-carrier-protein ACP. Also modifies the D- alanyl carrier protein but fai [...]
ydcC protein networkhttps://string-db.org/network/224308.BSU04630Putative lipoprotein; required for efficient sporulation.
alrA protein networkhttps://string-db.org/network/224308.BSU04640D-alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
ndoAI protein networkhttps://string-db.org/network/224308.BSU04650Antitoxin EndoAI; Antitoxin component of a type II toxin-antitoxin (TA) system. Antitoxin that directly inhibits activity of EndoA in vitro. Upon expression in E.coli counteracts inhibitory effec [...]
ndoA protein networkhttps://string-db.org/network/224308.BSU04660Endoribonuclease toxin; Toxic component of a type II toxin-antitoxin (TA) system. Specific for 5'-UACAU-3' sequences, cleaving after the first U. Yields cleavage products with 3' phosphate and 5' [...]
rsbRA protein networkhttps://string-db.org/network/224308.BSU04670Component of the piezosome (stressosome); Acts as a positive regulator of sigma-B activity in response to salt and heat stress by stimulating the activity of the RsbT kinase toward RsbS in vitro. [...]
rsbS protein networkhttps://string-db.org/network/224308.BSU04680Antagonist of RsbT; Negative regulator of sigma-B activity. Non-phosphorylated RsbS binds to RsbT, preventing its association with RsbU. Requires any one of RsbRA, RsbRB, RsbRC or RsbRD to seques [...]
rsbT protein networkhttps://string-db.org/network/224308.BSU04690Switch protein/serine-threonine kinase; Provides the crucial link between the upstream module (communication of environmental stress) and the downstream module (integration of the environmental s [...]
rsbU protein networkhttps://string-db.org/network/224308.BSU04700Serine phosphatase; Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to environmental stress conveyed from the RsbXST module.
rsbV protein networkhttps://string-db.org/network/224308.BSU04710Anti-anti-sigma factor (antagonist of RsbW); Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases [...]
rsbW protein networkhttps://string-db.org/network/224308.BSU04720Switch protein/serine kinase and anti-sigma factor (inhibitory sigma-B binding protein); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, Rs [...]
sigB protein networkhttps://string-db.org/network/224308.BSU04730RNA polymerase sigma-37 factor (sigma(B)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma B is not es [...]
rsbX protein networkhttps://string-db.org/network/224308.BSU04740Serine phosphatase; Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B acti [...]
ydcF protein networkhttps://string-db.org/network/224308.BSU04750Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ydcG protein networkhttps://string-db.org/network/224308.BSU04760Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0310 family.
ydcH protein networkhttps://string-db.org/network/224308.BSU04770Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
ydcI protein networkhttps://string-db.org/network/224308.BSU04780Putative RNA helicase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ydcK protein networkhttps://string-db.org/network/224308.BSU04790Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the SprT family.
ydcL protein networkhttps://string-db.org/network/224308.BSU04800Putative phage integrase; Putative integrase that is involved in the insertion of the integrative and conjugative element ICEBs1. Required for the excision of ICEBs1 from the donor cell genome an [...]
immA protein networkhttps://string-db.org/network/224308.BSU04810Site-specific protease cleaving ImmR; Involved in the regulation of horizontal gene transfer through the integrative and conjugative element ICEBs1. Required for degradation of the ICEBs1 repress [...]
immR protein networkhttps://string-db.org/network/224308.BSU04820Phage element (ICEBs1)transcriptional regulator (Xre family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin.
sacV protein networkhttps://string-db.org/network/224308.BSU04830Transcriptional regulator; Required for the excision of the integrative and conjugative element ICEBs1. Excision of ICEBs1 requires two sites, attL and attR, at the left and right ends of the int [...]
ydzL protein networkhttps://string-db.org/network/224308.BSU04839Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydcO protein networkhttps://string-db.org/network/224308.BSU04840Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ydcP protein networkhttps://string-db.org/network/224308.BSU04850Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydcQ protein networkhttps://string-db.org/network/224308.BSU04860Putative DNA wielding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ydcR protein networkhttps://string-db.org/network/224308.BSU04870Putative replication protein; Probable DNA relaxase involved in the transfer of the integrative and conjugative element ICEBs1. Required for the transfer of ICEBs1. Probably mediates conjugation [...]
ydcS protein networkhttps://string-db.org/network/224308.BSU04880Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydcT protein networkhttps://string-db.org/network/224308.BSU04890Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yddA protein networkhttps://string-db.org/network/224308.BSU04900Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yddB protein networkhttps://string-db.org/network/224308.BSU04910Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yddC protein networkhttps://string-db.org/network/224308.BSU04920Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yddD protein networkhttps://string-db.org/network/224308.BSU04930Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yddE protein networkhttps://string-db.org/network/224308.BSU04940Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yddF protein networkhttps://string-db.org/network/224308.BSU04950Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yddG protein networkhttps://string-db.org/network/224308.BSU04960Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yddH protein networkhttps://string-db.org/network/224308.BSU04970Cell wall hydrolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the peptidase C40 family.
yddI protein networkhttps://string-db.org/network/224308.BSU04980Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yddJ protein networkhttps://string-db.org/network/224308.BSU04990Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
yddK protein networkhttps://string-db.org/network/224308.BSU05000Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
rapI protein networkhttps://string-db.org/network/224308.BSU05010Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; Belongs to the RAP family.
phrI protein networkhttps://string-db.org/network/224308.BSU05020Secreted regulator of the activity of phosphatase RapI; Inhibitor of the activity of phosphatase RapI.
yddM protein networkhttps://string-db.org/network/224308.BSU05030Putative helicase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yddN protein networkhttps://string-db.org/network/224308.BSU05040Putative alkanal monooxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; To bacterial alkanal monoox [...]
lrpA protein networkhttps://string-db.org/network/224308.BSU05050Transcriptional regulator (Lrp/AsnC family); Negative regulation of glyA transcription and kinB-dependent sporulation.
lrpB protein networkhttps://string-db.org/network/224308.BSU05060Transcriptional regulator (Lrp/AsnC family); Negative regulation of glyA transcription and kinB-dependent sporulation.
yddQ protein networkhttps://string-db.org/network/224308.BSU05070Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the isochor [...]
yddR protein networkhttps://string-db.org/network/224308.BSU05080Putative metal-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belong [...]
yddS protein networkhttps://string-db.org/network/224308.BSU05090Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ydzM protein networkhttps://string-db.org/network/224308.BSU05099Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
yddT protein networkhttps://string-db.org/network/224308.BSU05100Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
ydeA protein networkhttps://string-db.org/network/224308.BSU05110Putative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the peptidase [...]
cspC protein networkhttps://string-db.org/network/224308.BSU05120Cold-shock protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
ydeB protein networkhttps://string-db.org/network/224308.BSU05130Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator; Bel [...]
ydzE protein networkhttps://string-db.org/network/224308.BSU05140Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ydeC protein networkhttps://string-db.org/network/224308.BSU05150Putative transcriptional regulator (AraC/XylS family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
ydeD protein networkhttps://string-db.org/network/224308.BSU05160Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ydeE protein networkhttps://string-db.org/network/224308.BSU05170Putative transcriptional regulator (AraC/XylS family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: puta [...]
ydeF protein networkhttps://string-db.org/network/224308.BSU05180Putative PLP-dependent transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
ydeG protein networkhttps://string-db.org/network/224308.BSU05190Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ydeH protein networkhttps://string-db.org/network/224308.BSU05200Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ydeI protein networkhttps://string-db.org/network/224308.BSU05210Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydeK protein networkhttps://string-db.org/network/224308.BSU05230Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ydeL protein networkhttps://string-db.org/network/224308.BSU05240Putative PLP-dependent transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
ydeM protein networkhttps://string-db.org/network/224308.BSU05250Putative dehydratase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
ydeN protein networkhttps://string-db.org/network/224308.BSU05260Alpha/beta hydrolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the RBBP9 family.
ydzF protein networkhttps://string-db.org/network/224308.BSU05270Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
ydeO protein networkhttps://string-db.org/network/224308.BSU05280Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ydeP protein networkhttps://string-db.org/network/224308.BSU05290Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
ydeQ protein networkhttps://string-db.org/network/224308.BSU05300Putative NAD(P)H oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs t [...]
ydeR protein networkhttps://string-db.org/network/224308.BSU05310Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ydeS protein networkhttps://string-db.org/network/224308.BSU05320Putative transcriptional regulator (TetR/AcrR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
ydzO protein networkhttps://string-db.org/network/224308.BSU05329Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
aseR protein networkhttps://string-db.org/network/224308.BSU05330Transcriptional regulator (metals sensing ArsR-SmtB repressors family); Metal-responsive transcriptional regulator that represses transcription of the aseR-ydfA operon by binding specifically to [...]
ydfA protein networkhttps://string-db.org/network/224308.BSU05340Putative metal-anion antiporter protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transport [...]
ydfB protein networkhttps://string-db.org/network/224308.BSU05350Conserved hypothetical protein; Evidence 7: Gene remnant; Belongs to the acetyltransferase family.
ydfC protein networkhttps://string-db.org/network/224308.BSU05360Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ydfD protein networkhttps://string-db.org/network/224308.BSU05370Putative PLP-dependent transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
ydfE protein networkhttps://string-db.org/network/224308.BSU05380Putative flavoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ydfF protein networkhttps://string-db.org/network/224308.BSU05390Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
ydfG protein networkhttps://string-db.org/network/224308.BSU05400Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydzP protein networkhttps://string-db.org/network/224308.BSU05408Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ydzQ protein networkhttps://string-db.org/network/224308.BSU05409Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ydfH protein networkhttps://string-db.org/network/224308.BSU05410Two-component sensor histidine kinase [YdfI]; Member of the two-component regulatory system YdfH/YdfI. May activate YdfI by phosphorylation.
ydfI protein networkhttps://string-db.org/network/224308.BSU05420Two-component response regulator [YdfH]; Member of the two-component regulatory system YdfH/YdfI. Regulates the transcription of ydfJ by binding to its promoter region.
ydfJ protein networkhttps://string-db.org/network/224308.BSU05430Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs [...]
nap protein networkhttps://string-db.org/network/224308.BSU05440Carboxylesterase NP; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the AB hydrolase superfamily.
ydfK protein networkhttps://string-db.org/network/224308.BSU05450Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ydfL protein networkhttps://string-db.org/network/224308.BSU05460Putative transcriptional regulator of efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: p [...]
ydfM protein networkhttps://string-db.org/network/224308.BSU05470Putative divalent cation efflux transporter; Primary efflux pump for manganese. May prevent manganese intoxication; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family [...]
ydfN protein networkhttps://string-db.org/network/224308.BSU05480Putative oxidoreductase; Putative nitroreductase that may contribute to the degradation of aromatic compounds.
ydfO protein networkhttps://string-db.org/network/224308.BSU05490Putative dioxygenase; Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds.
ydfP protein networkhttps://string-db.org/network/224308.BSU05500Putative membrane bound oxidoreductase; Putative oxidoreductase that may contribute to the degradation of aromatic compounds.
ydfQ protein networkhttps://string-db.org/network/224308.BSU05510Putative thioredoxin or thiol-disulfide isomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
ydzH protein networkhttps://string-db.org/network/224308.BSU05520Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydzR protein networkhttps://string-db.org/network/224308.BSU05529Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 19383706, 20709900; Belongs to the GerPA/GerPF family.
ydfR protein networkhttps://string-db.org/network/224308.BSU05530Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydfS protein networkhttps://string-db.org/network/224308.BSU05540Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
cotP protein networkhttps://string-db.org/network/224308.BSU05550Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
ydgA protein networkhttps://string-db.org/network/224308.BSU05560Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydgB protein networkhttps://string-db.org/network/224308.BSU05570Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydgC protein networkhttps://string-db.org/network/224308.BSU05580Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
ydgD protein networkhttps://string-db.org/network/224308.BSU05590Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydgE protein networkhttps://string-db.org/network/224308.BSU05600Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
vmlR protein networkhttps://string-db.org/network/224308.BSU05610ATP-binding cassette efflux transporter; Recognizes and binds in the vacant E-site of ribosomes stalled by some peptidyltransferase center (PTC)-targeting antibiotics. Makes contact with the PTC [...]
ydgF protein networkhttps://string-db.org/network/224308.BSU05620Putative amino acid permease; Probable amino-acid or metabolite transport protein; Belongs to the amino acid-polyamine-organocation (APC) superfamily.
dinB protein networkhttps://string-db.org/network/224308.BSU05630Nuclease inhibitor; Evidence 2b: Function of strongly homologous gene; regulator.
ydgG protein networkhttps://string-db.org/network/224308.BSU05640Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
ydgH protein networkhttps://string-db.org/network/224308.BSU05650Putative membrane component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component; Belongs to the res [...]
ydgI protein networkhttps://string-db.org/network/224308.BSU05660Putative dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ydgJ protein networkhttps://string-db.org/network/224308.BSU05670Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
ydgK protein networkhttps://string-db.org/network/224308.BSU05680Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ydhB protein networkhttps://string-db.org/network/224308.BSU05690Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ydhC protein networkhttps://string-db.org/network/224308.BSU05700Putative transcriptional regulator (GntR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
ydhD protein networkhttps://string-db.org/network/224308.BSU05710Spore cortex lytic enzyme; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type cp: cell process; Belongs to the glycosyl hydrolase 18 family. C [...]
ydhE protein networkhttps://string-db.org/network/224308.BSU05720Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
ydhF protein networkhttps://string-db.org/network/224308.BSU05730Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein.
phoB protein networkhttps://string-db.org/network/224308.BSU05740Alkaline phosphatase III; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the alkaline phosphatase family.
fra protein networkhttps://string-db.org/network/224308.BSU05750Frataxin; Possible global iron distributor for the cell. Promotes the biosynthesis of iron-sulfur clusters by delivering Fe to the iron- sulfur cluster assembly scaffold protein SufU. In the pres [...]
ydhH protein networkhttps://string-db.org/network/224308.BSU05760Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydhI protein networkhttps://string-db.org/network/224308.BSU05770Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ydhJ protein networkhttps://string-db.org/network/224308.BSU05780Putative metal-dependent phosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ydhK protein networkhttps://string-db.org/network/224308.BSU05790Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
pbuE protein networkhttps://string-db.org/network/224308.BSU05800Hypoxanthine efflux transporter; Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and inosine, as well as purine bases guanine, adenine and hypoxanthine, and purine [...]
gmuB protein networkhttps://string-db.org/network/224308.BSU05810Oligo-alpha-mannoside phosphotransferase system enzyme IIB; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes [...]
gmuA protein networkhttps://string-db.org/network/224308.BSU05820Oligo-alpha-mannoside phosphotransferase system enzyme IIA; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes [...]
gmuC protein networkhttps://string-db.org/network/224308.BSU05830Oligo-alpha-mannoside phosphotransferase system enzyme IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes [...]
gmuD protein networkhttps://string-db.org/network/224308.BSU05840Mannoside-phospho-beta-d-glucosidase; Phospho-beta-D-glucosidase that seems to be involved in the degradation of glucomannan. Is also capable of hydrolyzing aryl- phospho-beta-D-glucosides, altho [...]
gmuR protein networkhttps://string-db.org/network/224308.BSU05850Transcriptional regulator (GntR family); Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan.
gmuE protein networkhttps://string-db.org/network/224308.BSU05860ROK fructokinase; Seems to be involved in the degradation of glucomannan.
gmuF protein networkhttps://string-db.org/network/224308.BSU05870Phosphohexomutase; Seems to be involved in the degradation of glucomannan. Belongs to the mannose-6-phosphate isomerase type 1 family.
gmuG protein networkhttps://string-db.org/network/224308.BSU05880Exported mannan endo-1,4-beta-mannosidase; Involved in the degradation of glucomannan. Catalyzes the endo hydrolysis of beta-1,4-linked mannan, galactomannan and glucomannan; Belongs to the glyco [...]
thiL protein networkhttps://string-db.org/network/224308.BSU05900tRNA-Asp; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate k [...]
tsaE protein networkhttps://string-db.org/network/224308.BSU05910tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with a [...]
tsaB protein networkhttps://string-db.org/network/224308.BSU05920tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with a [...]
rimI protein networkhttps://string-db.org/network/224308.BSU05930Ribosomal protein S18 alanine N-acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.
tsaD protein networkhttps://string-db.org/network/224308.BSU05940tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with a [...]
ydiF protein networkhttps://string-db.org/network/224308.BSU05950Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative tr [...]
moaC protein networkhttps://string-db.org/network/224308.BSU05960Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC fami [...]
rex protein networkhttps://string-db.org/network/224308.BSU05970Transcription repressor of cydABCD and yjlC-ndh expression; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
tatAY protein networkhttps://string-db.org/network/224308.BSU05980Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- argi [...]
tatCY protein networkhttps://string-db.org/network/224308.BSU05990Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- argi [...]
ydiK protein networkhttps://string-db.org/network/224308.BSU06000Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydiL protein networkhttps://string-db.org/network/224308.BSU06010Putative membrane protease; May function as endopeptidase which proteolytically removes the C-terminal three residues of farnesylated peptides containing the CAAX motif where C is cysteine, A is [...]
groES protein networkhttps://string-db.org/network/224308.BSU06020Chaperonin small subunit; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter; Belongs to the GroES chaperonin family.
groEL protein networkhttps://string-db.org/network/224308.BSU06030Chaperonin large subunit; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
ydiM protein networkhttps://string-db.org/network/224308.BSU06040Hypothetical protein; Evidence 7: Gene remnant; putative enzyme.
ydzU protein networkhttps://string-db.org/network/224308.BSU06048Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
bsuMA protein networkhttps://string-db.org/network/224308.BSU06060Conserved hypothetical protein; This methylase may recognize the double-stranded sequence CTCGAG, causing specific methylation on C-? on both strands, and protects the DNA from cleavage by the Bs [...]
bsuMB protein networkhttps://string-db.org/network/224308.BSU06070DNA-methyltransferase (cytosine-specific); This methylase may recognize the double-stranded sequence CTCGAG, causing specific methylation on C-? on both strands, and protects the DNA from cleavag [...]
bsuRA protein networkhttps://string-db.org/network/224308.BSU06090Putative phosphomannomutase; Recognizes the double-stranded sequence CTCGAG; the cleavage site is unknown.
bsuRB protein networkhttps://string-db.org/network/224308.BSU06100Type-2 restriction enzyme BsuMI component BsuRB (YdiS); Recognizes the double-stranded sequence CTCGAG; the cleavage site is unknown.
bsuRC protein networkhttps://string-db.org/network/224308.BSU06110Type-2 restriction enzyme BsuMI component BsuRC (YdjA); Recognizes the double-stranded sequence CTCGAG; the cleavage site is unknown.
ydjB protein networkhttps://string-db.org/network/224308.BSU06120Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ydjC protein networkhttps://string-db.org/network/224308.BSU06130Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
gutR protein networkhttps://string-db.org/network/224308.BSU06140Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB).
gutB protein networkhttps://string-db.org/network/224308.BSU06150Glucitol (sorbitol) dehydrogenase; Polyol dehydrogenase that catalyzes the NAD(+)-dependent oxidation of various sugar alcohols. Is mostly active with D-sorbitol (D-glucitol), xylitol and L-idito [...]
gutP protein networkhttps://string-db.org/network/224308.BSU06160H+-glucitol symporter; Probably involved in glucitol uptake; Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
ydjE protein networkhttps://string-db.org/network/224308.BSU06170Putative sugar kinase (ribokinase family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; [...]
pspA protein networkhttps://string-db.org/network/224308.BSU06180Phage shock protein A homolog; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin.
ydjG protein networkhttps://string-db.org/network/224308.BSU06190Putative phage replication protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
ydjH protein networkhttps://string-db.org/network/224308.BSU06200Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydjI protein networkhttps://string-db.org/network/224308.BSU06210Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
ydjJ protein networkhttps://string-db.org/network/224308.BSU06220Putative membrane associated potassium channel; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative tr [...]
iolT protein networkhttps://string-db.org/network/224308.BSU06230Myo-inositol transporter; Major myo-inositol uptake transporter.
bdhA protein networkhttps://string-db.org/network/224308.BSU06240Acetoin reductase/2,3-butanediol dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
ydjM protein networkhttps://string-db.org/network/224308.BSU06250Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydjN protein networkhttps://string-db.org/network/224308.BSU06260Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
ydzJ protein networkhttps://string-db.org/network/224308.BSU06269Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ydjO protein networkhttps://string-db.org/network/224308.BSU06270Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ydjP protein networkhttps://string-db.org/network/224308.BSU06280Putative peroxydase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yeaA protein networkhttps://string-db.org/network/224308.BSU06290Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
cotA protein networkhttps://string-db.org/network/224308.BSU06300Outer spore coat copper-dependent laccase; Involved in brown pigmentation during sporogenesis.
gabP protein networkhttps://string-db.org/network/224308.BSU06310Gamma-aminobutyrate (GABA) permease; High-affinity uptake system for GABA. Functions also as a low-affinity proline importer; Belongs to the amino acid-polyamine-organocation (APC) superfamily. A [...]
ydzX protein networkhttps://string-db.org/network/224308.BSU06319Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yeaB protein networkhttps://string-db.org/network/224308.BSU06320Putative cation efflux transporter; Secondary manganese efflux system. May prevent manganese intoxication; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
yeaC protein networkhttps://string-db.org/network/224308.BSU06330Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the MoxR family.
yeaD protein networkhttps://string-db.org/network/224308.BSU06340Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yebA protein networkhttps://string-db.org/network/224308.BSU06350Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
guaA protein networkhttps://string-db.org/network/224308.BSU06360GMP synthetase; Catalyzes the synthesis of GMP from XMP.
pbuG protein networkhttps://string-db.org/network/224308.BSU06370Hypoxanthine/guanine permease; Involved in the uptake of the purine bases hypoxanthine and guanine; Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [...]
yebC protein networkhttps://string-db.org/network/224308.BSU06380Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yebD protein networkhttps://string-db.org/network/224308.BSU06390Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yebE protein networkhttps://string-db.org/network/224308.BSU06400Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yebG protein networkhttps://string-db.org/network/224308.BSU06410Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
purE protein networkhttps://string-db.org/network/224308.BSU06420N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
purK protein networkhttps://string-db.org/network/224308.BSU06430N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR [...]
purB protein networkhttps://string-db.org/network/224308.BSU06440Adenylosuccinate lyase; Influences the affinity of glutamyl--tRNA ligase for its substrates and increases its thermostability; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
purC protein networkhttps://string-db.org/network/224308.BSU06450Phosphoribosylaminoimidazole succinocarboxamide synthetase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the SAICA [...]
purS protein networkhttps://string-db.org/network/224308.BSU06460Factor required for phosphoribosylformylglycinamidine synthetase activity; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes t [...]
purQ protein networkhttps://string-db.org/network/224308.BSU06470Phosphoribosylformylglycinamidine synthetase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion [...]
purL protein networkhttps://string-db.org/network/224308.BSU06480Phosphoribosylformylglycinamidine synthetase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversio [...]
purF protein networkhttps://string-db.org/network/224308.BSU06490Glutamine phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
purM protein networkhttps://string-db.org/network/224308.BSU06500Phosphoribosylaminoimidazole synthetase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.
purN protein networkhttps://string-db.org/network/224308.BSU06510Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylg [...]
purH protein networkhttps://string-db.org/network/224308.BSU06520Fused phosphoribosylaminoimidazole carboxy formyl formyltransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.
purD protein networkhttps://string-db.org/network/224308.BSU06530Phosphoribosylglycinamide synthetase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
yezC protein networkhttps://string-db.org/network/224308.BSU06540Putative transcriptional regulator (Lrp/AsnC family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putat [...]
yecA protein networkhttps://string-db.org/network/224308.BSU06550Putative amino acid/polyamine permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporte [...]
yezF protein networkhttps://string-db.org/network/224308.BSU06559Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yerA protein networkhttps://string-db.org/network/224308.BSU06560Putative adenine deaminase YerA; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yerB protein networkhttps://string-db.org/network/224308.BSU06570Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein.
yerC protein networkhttps://string-db.org/network/224308.BSU06580Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yerD protein networkhttps://string-db.org/network/224308.BSU06590Putative flavoenzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
pcrB protein networkhttps://string-db.org/network/224308.BSU06600Heptaprenylglyceryl-phosphate synthase; Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of [...]
pcrA protein networkhttps://string-db.org/network/224308.BSU06610ATP-dependent DNA helicase; DNA helicase used for plasmid rolling-circle replication and also involved in UV repair.
ligA protein networkhttps://string-db.org/network/224308.BSU06620DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sourc [...]
yerH protein networkhttps://string-db.org/network/224308.BSU06630Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein.
yerI protein networkhttps://string-db.org/network/224308.BSU06640Putative kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the pseudomona [...]
sapB protein networkhttps://string-db.org/network/224308.BSU06650Membrane component; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type ph: phenotype.
opuE protein networkhttps://string-db.org/network/224308.BSU06660Proline transporter; Catalyzes the uptake of extracellular proline under high- osmolarity growth conditions. Essential for the use of proline present in the environment as an osmoprotectant.
gatC protein networkhttps://string-db.org/network/224308.BSU06670glutamyl-tRNA(Gln) amidotransferase (subunit C); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) [...]
gatA protein networkhttps://string-db.org/network/224308.BSU06680glutamyl-tRNA(Gln) amidotransferase (subunit A); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl [...]
gatB protein networkhttps://string-db.org/network/224308.BSU06690glutamyl-tRNA(Gln) amidotransferase (subunit B); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) [...]
yerO protein networkhttps://string-db.org/network/224308.BSU06700Putative transcriptional regulator (TetR/AcrR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: puta [...]
swrC protein networkhttps://string-db.org/network/224308.BSU06710Transporter involved in surfactin self-resistance; Required for self-resistance to surfactin, an antimicrobial lipopeptide surfactant produced by B.subtilis. Also required for swarming motility; [...]
dagK protein networkhttps://string-db.org/network/224308.BSU06720Diacylglycerol kinase; Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed fr [...]
rlmCD protein networkhttps://string-db.org/network/224308.BSU06730Methyltransferase of m5U747 and m5U1939 in 23S RNA; Catalyzes the formation of 5-methyl-uridine at positions 747 (m5U747) and 1939 (m5U1939) in 23S rRNA.
yefB protein networkhttps://string-db.org/network/224308.BSU06740Putative site-specific recombinase / invertase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative en [...]
yefC protein networkhttps://string-db.org/network/224308.BSU06750Putative resolvase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the site-sp [...]
yeeA protein networkhttps://string-db.org/network/224308.BSU06760Putative restriction type II methylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yeeB protein networkhttps://string-db.org/network/224308.BSU06770Putative DNA helicase / endonuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belo [...]
yeeC protein networkhttps://string-db.org/network/224308.BSU06780Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Product type h: extrachromosomal origin.
yeeD protein networkhttps://string-db.org/network/224308.BSU06790Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yezA protein networkhttps://string-db.org/network/224308.BSU06800Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yezG protein networkhttps://string-db.org/network/224308.BSU06811Conserved hypothetical protein; Probable antitoxin component of a type II toxin-antitoxin (TA) system. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not [...]
yeeF protein networkhttps://string-db.org/network/224308.BSU06812Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic [...]
yeeG protein networkhttps://string-db.org/network/224308.BSU06820Putative phage receptor protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane componen [...]
rapH protein networkhttps://string-db.org/network/224308.BSU06830Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the RAP family.
phrH protein networkhttps://string-db.org/network/224308.BSU06839Hexapeptide inhibitor of regulatory cascade; Inhibitor of the activity of phosphatase RapH. May inhibit the rapH promoter after import into the cytoplasm.
yeeI protein networkhttps://string-db.org/network/224308.BSU06840Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yeeK protein networkhttps://string-db.org/network/224308.BSU06850Spore associated protein; Part of the spore coat.
yezE protein networkhttps://string-db.org/network/224308.BSU06860Putative transcriptional regulator (TetR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
yesE protein networkhttps://string-db.org/network/224308.BSU06870Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the limonene-1,2-epoxide hydrolase family.
yesF protein networkhttps://string-db.org/network/224308.BSU06880Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the Nm [...]
cotJA protein networkhttps://string-db.org/network/224308.BSU06890Component of the inner spore coat; The cotJ operon proteins affect spore coat composition. They are either required for the normal formation of the inner layers of the coat or are themselves stru [...]
cotJB protein networkhttps://string-db.org/network/224308.BSU06900Component of the inner spore coat; The cotJ operon proteins affect spore coat composition. They are either required for the normal formation of the inner layers of the coat or are themselves stru [...]
cotJC protein networkhttps://string-db.org/network/224308.BSU06910Component of the inner spore coat; The cotJ operon proteins affect spore coat composition. They are either required for the normal formation of the inner layers of the coat or are themselves stru [...]
yesJ protein networkhttps://string-db.org/network/224308.BSU06920Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the [...]
yesK protein networkhttps://string-db.org/network/224308.BSU06930Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yesL protein networkhttps://string-db.org/network/224308.BSU06940Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yesM protein networkhttps://string-db.org/network/224308.BSU06950Two-component sensor histidine kinase [YesN]; Member of the two-component regulatory system YesM/YesN. Probably activates YesN by phosphorylation.
yesN protein networkhttps://string-db.org/network/224308.BSU06960Two-component response regulator [YesM]; Member of the two-component regulatory system YesM/YesN.
yesO protein networkhttps://string-db.org/network/224308.BSU06970Pectin degradation byproducts-binding lipoprotein; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. Belongs to the bacterial solute-binding protein 1 [...]
rhgP protein networkhttps://string-db.org/network/224308.BSU06980Rhamnogalacturonan permease; Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the [...]
rhgQ protein networkhttps://string-db.org/network/224308.BSU06990Rhamnogalacturonan permease; Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the [...]
rhgH protein networkhttps://string-db.org/network/224308.BSU07000Rhamnogalacturonan hydrolase; Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D-galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuro [...]
yesS protein networkhttps://string-db.org/network/224308.BSU07010Transcriptional regulator (AraC/XylS family); Probable transcription factor regulating the pathway responsible for rhamnogalacturonan depolymerization.
rhgT protein networkhttps://string-db.org/network/224308.BSU07020Rhamnogalacturonan acetylesterase; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity, and shows strong p [...]
yesU protein networkhttps://string-db.org/network/224308.BSU07030Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16781735, 17449691.
yesV protein networkhttps://string-db.org/network/224308.BSU07040Putative integral inner membrane component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membra [...]
rhgW protein networkhttps://string-db.org/network/224308.BSU07050Rhamnogalacturonan endolyase; Pectinolytic enzyme that degrades type I rhamnogalacturonan from plant cell walls and releases oligosaccharide products. Degrades rhamnogalacturonan, polygalacturoni [...]
rhgX protein networkhttps://string-db.org/network/224308.BSU07060Rhamnogalacturonan exolyase YesX; Pectinolytic enzyme that degrades type I rhamnogalacturonan from plant cell walls and releases disaccharide products. Degrades rhamnogalacturonan, polygalacturon [...]
yesY protein networkhttps://string-db.org/network/224308.BSU07070Rhamnogalacturonan acetylesterase; May play a role in the degradation of rhamnogalacturonan derived from plant cell walls. Probably has broad substrate specificity and may degrade several types o [...]
rhgZ protein networkhttps://string-db.org/network/224308.BSU07080Beta-galacturonidase; May play a role in the degradation of rhamnogalacturonan derived from plant cell walls; Belongs to the glycosyl hydrolase 42 family.
yetA protein networkhttps://string-db.org/network/224308.BSU07090Putative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
lplA protein networkhttps://string-db.org/network/224308.BSU07100Lipoprotein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type lp: lipoprotein.
lplB protein networkhttps://string-db.org/network/224308.BSU07110Putative ABC transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
lplC protein networkhttps://string-db.org/network/224308.BSU07120Putative ABC transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
lplD protein networkhttps://string-db.org/network/224308.BSU07130Putative glycosidase; Alpha-galacturonidase able to catalyze the hydrolysis of the chromogenic substrate p-nitrophenyl-alpha-D-galacturonic acid (pNPalphaGalUA), and of the probable natural subst [...]
yetF protein networkhttps://string-db.org/network/224308.BSU07140Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
hmoA protein networkhttps://string-db.org/network/224308.BSU07150Heme-degrading monooxygenase; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a su [...]
yetH protein networkhttps://string-db.org/network/224308.BSU07160Putative lyase/dioxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yezD protein networkhttps://string-db.org/network/224308.BSU07190Putative paralog of RsbR; Evidence 7: Gene remnant; Product type pr: putative regulator.
yetJ protein networkhttps://string-db.org/network/224308.BSU07200Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane compo [...]
yetK protein networkhttps://string-db.org/network/224308.BSU07210Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yetL protein networkhttps://string-db.org/network/224308.BSU07220Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
yetM protein networkhttps://string-db.org/network/224308.BSU07230Putative hydroxylase/monooxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yetN protein networkhttps://string-db.org/network/224308.BSU07240Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
cypD protein networkhttps://string-db.org/network/224308.BSU07250Putative bifunctional P-450/NADPH-P450 reductase 1; Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of a range of long-chain fatty acids, with a preference for long-chain unsatur [...]
ltaSA protein networkhttps://string-db.org/network/224308.BSU07260Exported glycerol phosphate lipoteichoic acid synthetase and anion-binding protein; Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses [...]
yfnH protein networkhttps://string-db.org/network/224308.BSU07270Putative glucose-1-phosphate cytidylyltransferase; Catalyzes the transfer of a CMP moiety from CTP to glucose 1- phosphate.
yfnG protein networkhttps://string-db.org/network/224308.BSU07280Putative CDP-sugar-dehydratase/epimerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yfnF protein networkhttps://string-db.org/network/224308.BSU07290Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yfnE protein networkhttps://string-db.org/network/224308.BSU07300Putative glycosyltransferase (complex carbohydrate synthase); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type p [...]
yfnD protein networkhttps://string-db.org/network/224308.BSU07310Putative glycosyltransferase (complex carbohydrate synthase); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type p [...]
yfnC protein networkhttps://string-db.org/network/224308.BSU07320Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yfnB protein networkhttps://string-db.org/network/224308.BSU07330Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the HAD-lik [...]
yfnA protein networkhttps://string-db.org/network/224308.BSU07340Metabolite permease; Involved in import of methylthioribose (MTR) into the cell.
yfmT protein networkhttps://string-db.org/network/224308.BSU07350Putative aldehyde dehydrogenase; A benzaldehyde dehydrogenase able to act on substrates with 3- and 4-hydroxy and methoxy substitutions; converts vanillin (4- hydroxy-3-methoxybenzaldehyde) to va [...]
yfmS protein networkhttps://string-db.org/network/224308.BSU07360Putative chemotaxis sensory transducer; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outsid [...]
uup protein networkhttps://string-db.org/network/224308.BSU07370Putative ABC protein involved in RecA-independent precise excision of transposons; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited hom [...]
yfmQ protein networkhttps://string-db.org/network/224308.BSU07380Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yfmP protein networkhttps://string-db.org/network/224308.BSU07390Transcriptional regulator (MerR family) of metal efflux transporter expression; Repressor of the yfmOP operon. A mutation in yfmP leads to overexpression of yfmO, probably causing a decrease in c [...]
yfmO protein networkhttps://string-db.org/network/224308.BSU07400Metal efflux transporter; Acts to efflux copper or a copper complex. It is possible that YfmO could contribute to copper resistance. Belongs to the major facilitator superfamily.
yfmN protein networkhttps://string-db.org/network/224308.BSU07410Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yfmM protein networkhttps://string-db.org/network/224308.BSU07420Putative ATP-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
yfmL protein networkhttps://string-db.org/network/224308.BSU07430Putative ATP-dependent RNA helicase; A probable DEAD-box RNA helicase that plays a role in ribosomal 50S subunit assembly. May be a non-specific RNA helicase. Belongs to the DEAD box helicase fam [...]
yfmK protein networkhttps://string-db.org/network/224308.BSU07440Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the [...]
yfmJ protein networkhttps://string-db.org/network/224308.BSU07450Putative oxidoreductase; Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds; Belongs to the NADP-dependent oxidoreductase L4BD family.
yfmI protein networkhttps://string-db.org/network/224308.BSU07460Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yfmG protein networkhttps://string-db.org/network/224308.BSU07480Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yfmF protein networkhttps://string-db.org/network/224308.BSU07490Iron-dicitrate ABC transporter (ATP-binding protein); Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Responsible for energy coupling to the transport sys [...]
yfmE protein networkhttps://string-db.org/network/224308.BSU07500Iron-dicitrate ABC transporter (permease); Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membr [...]
yfmD protein networkhttps://string-db.org/network/224308.BSU07510Iron-dicitrate ABC transporter (permease); Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membr [...]
yfmC protein networkhttps://string-db.org/network/224308.BSU07520Iron-dicitrate ABC transporter (binding lipoprotein); Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to th [...]
yfmB protein networkhttps://string-db.org/network/224308.BSU07530Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yflT protein networkhttps://string-db.org/network/224308.BSU07550Heat stress induced protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
pel protein networkhttps://string-db.org/network/224308.BSU07560Pectate lyase; Produces unsaturated products from polygalacturonate.
yflS protein networkhttps://string-db.org/network/224308.BSU075702-oxoglutarate/malate transporter; Might be a malate transporter.
citS protein networkhttps://string-db.org/network/224308.BSU07580Two-component sensor histidine kinase; Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Functions probably as a membrane-associated prote [...]
citT protein networkhttps://string-db.org/network/224308.BSU07590Two-component response regulator; Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to acti [...]
yflP protein networkhttps://string-db.org/network/224308.BSU07600Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0065 (bug) family.
citM protein networkhttps://string-db.org/network/224308.BSU07610Transporter of divalent metal ions/citrate complexes; Proton motive force-driven secondary transporter that mediates the transport of citrate complexed to Mg(2+). Cotransports at least two proton [...]
yflN protein networkhttps://string-db.org/network/224308.BSU07620Putative metal-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the metallo- [...]
nosA protein networkhttps://string-db.org/network/224308.BSU07630Nitric-oxide synthase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
yflL protein networkhttps://string-db.org/network/224308.BSU07640Putative acylphosphatase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the a [...]
yflK protein networkhttps://string-db.org/network/224308.BSU07650Putative sulfur carrier; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
yflJ protein networkhttps://string-db.org/network/224308.BSU07660Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yflI protein networkhttps://string-db.org/network/224308.BSU07670Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yflH protein networkhttps://string-db.org/network/224308.BSU07680Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 1070366, 1266368.
mapB protein networkhttps://string-db.org/network/224308.BSU07690Methionine aminopeptidase B; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncha [...]
nagP protein networkhttps://string-db.org/network/224308.BSU07700Phosphotransferase system (PTS) N-acetylglucosamine-specific enzyme IICB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -tra [...]
ltaSB protein networkhttps://string-db.org/network/224308.BSU07710Enzyme responsible for polyglycerolphosphate LTA synthesis; Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (P [...]
yflD protein networkhttps://string-db.org/network/224308.BSU07720Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yflB protein networkhttps://string-db.org/network/224308.BSU07735Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yflA protein networkhttps://string-db.org/network/224308.BSU07750Putative aminoacid transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yfkT protein networkhttps://string-db.org/network/224308.BSU07760Putative spore germination integral inner membrane protein; May be involved in spore germination. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SG [...]
yfkS protein networkhttps://string-db.org/network/224308.BSU07770Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yfkR protein networkhttps://string-db.org/network/224308.BSU07780Putative spore germination protein; May be involved in spore germination. Belongs to the GerABKC lipoprotein family.
yfkQ protein networkhttps://string-db.org/network/224308.BSU07790Putative spore germination protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
treP protein networkhttps://string-db.org/network/224308.BSU07800Phosphotransferase system (PTS) trehalose-specific enzyme IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport syst [...]
treA protein networkhttps://string-db.org/network/224308.BSU07810Trehalose-6-phosphate hydrolase; Hydrolyzes trehalose-6-phosphate to glucose and glucose 6- phosphate. Can also very effectively hydrolyzes p-nitrophenyl-alpha-D- glucopyranoside, but not lactose [...]
treR protein networkhttps://string-db.org/network/224308.BSU07820Transcriptional regulator (GntR family); Repressor for the trePA operon. It is able to bind trehalose- 6-phosphate.
nfsB protein networkhttps://string-db.org/network/224308.BSU07830NAD(P)H-flavin oxidoreductase (nitroreductase); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the nitroreductase family.
yfkN protein networkhttps://string-db.org/network/224308.BSU07840Exported 2',3'-cyclic-nucleotide 2'-phosphodiesterase, 2' (or 3') nucleotidase and 5' nucleotidase; Catalyzes the release of inorganic phosphate from 2',3'- cyclic nucleotides through consecutive [...]
yfkM protein networkhttps://string-db.org/network/224308.BSU07850General stress protein 18; Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins.
yfkL protein networkhttps://string-db.org/network/224308.BSU07860Efflux transporter; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; transporter.
yfkK protein networkhttps://string-db.org/network/224308.BSU07870Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0435 family.
yfkJ protein networkhttps://string-db.org/network/224308.BSU07880Protein-tyrosine-phosphatase; Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance.
yfkI protein networkhttps://string-db.org/network/224308.BSU07890Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15995210.
rbn protein networkhttps://string-db.org/network/224308.BSU07900Putative ribonuclease BN; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yfkF protein networkhttps://string-db.org/network/224308.BSU07910Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yfkE protein networkhttps://string-db.org/network/224308.BSU07920Putative H+/Ca2+ antiporter; Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. Does not transport sodium or potassium. Belongs to the Ca(2+):cation antiporter (CaCA) ( [...]
yfkD protein networkhttps://string-db.org/network/224308.BSU07930Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yfkC protein networkhttps://string-db.org/network/224308.BSU07940Putative mechanosensitive ion channel; May play a role in resistance to osmotic downshock. Belongs to the MscS (TC 1.A.23) family.
yfkA protein networkhttps://string-db.org/network/224308.BSU07955Putative Fe-S oxidoreductase, radical SAM superfamily; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: puta [...]
yfjT protein networkhttps://string-db.org/network/224308.BSU07970Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
pdaA protein networkhttps://string-db.org/network/224308.BSU07980Exported N-acetylmuramic acid deacetylase; Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in glycan strands of peptidoglycan, leading to the formation of muramic delta-lact [...]
yfjR protein networkhttps://string-db.org/network/224308.BSU07990Putative beta-hydroxyacid dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; B [...]
yfjQ protein networkhttps://string-db.org/network/224308.BSU08000Putative divalent cation transport protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
yfjP protein networkhttps://string-db.org/network/224308.BSU08010Putative DNA-modified purine glycosidase; Hydrolysis of the deoxyribose N-glycosidic bond to excise 3- methyladenine, 3-methylguanine, 7-methylguanine, O2-methylthymine, and O2-methylcytosine fro [...]
yfjO protein networkhttps://string-db.org/network/224308.BSU08020Putative RNA methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to [...]
dusC protein networkhttps://string-db.org/network/224308.BSU08030tRNA-dihydrouridine synthase 2; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines [...]
yfjM protein networkhttps://string-db.org/network/224308.BSU08040Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yfjL protein networkhttps://string-db.org/network/224308.BSU08050Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
acoA protein networkhttps://string-db.org/network/224308.BSU08060Acetoin dehydrogenase E1 component (TPP-dependent alpha subunit); Catalyzes the 2,6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde. The alpha subunit is prob [...]
acoB protein networkhttps://string-db.org/network/224308.BSU08070Acetoin dehydrogenase E1 component (TPP-dependent beta subunit); Catalyzes the 2,6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde.
acoC protein networkhttps://string-db.org/network/224308.BSU08080Acetoin dehydrogenase E2 component (dihydrolipoamide acetyltransferase); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
acoL protein networkhttps://string-db.org/network/224308.BSU08090Acetoin dehydrogenase E3 component (dihydrolipoamide dehydrogenase); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-I pyridi [...]
acoR protein networkhttps://string-db.org/network/224308.BSU08100Transcriptional regulator; Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex.
sspH protein networkhttps://string-db.org/network/224308.BSU08110Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process; Belongs to the SspH family.
yfjF protein networkhttps://string-db.org/network/224308.BSU08120Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
yfjE protein networkhttps://string-db.org/network/224308.BSU08130Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yfjD protein networkhttps://string-db.org/network/224308.BSU08140Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yfjC protein networkhttps://string-db.org/network/224308.BSU08150Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yfjB protein networkhttps://string-db.org/network/224308.BSU08160Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yfjA protein networkhttps://string-db.org/network/224308.BSU08170Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the WXG100 family.
malA protein networkhttps://string-db.org/network/224308.BSU081806-phospho-alpha-glucosidase; Hydrolyzes maltose-6'-phosphate and trehalose-6'-phosphate. Is involved in the catabolism of alpha-glycosides accumulated via a phosphoenolpyruvate-dependent maltose [...]
malR protein networkhttps://string-db.org/network/224308.BSU08190Transcriptional activator of the Mal operon; Positive regulator of the glv operon expression, which consists of GlvA, GlvR and GlvC.
malP protein networkhttps://string-db.org/network/224308.BSU08200Phosphotransferase system (PTS) maltose-specific enzyme IICB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system [...]
malQ protein networkhttps://string-db.org/network/224308.BSU08210Maltose and maltodextrin ABC transporter subunit (ATP-binding protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter.
yfiC protein networkhttps://string-db.org/network/224308.BSU08220Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative tr [...]
catD protein networkhttps://string-db.org/network/224308.BSU08230Catechol-2,3-dioxygenase membrane subunit; Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol.
catE protein networkhttps://string-db.org/network/224308.BSU08240Catechol-2,3-dioxygenase subunit; Involved in the meta cleavage of catechol to 2-hydroxymuconic semialdehyde. Essential for growth and viability in the presence of catechol and probably involved [...]
yfiF protein networkhttps://string-db.org/network/224308.BSU08250Putative transcriptional regulator (AraC/XylS family; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
yfiG protein networkhttps://string-db.org/network/224308.BSU08260Putative sugar transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yfiH protein networkhttps://string-db.org/network/224308.BSU08270Putative sugar-phosphate epimerase/isomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzy [...]
yfiI protein networkhttps://string-db.org/network/224308.BSU08280Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the Gf [...]
yfiJ protein networkhttps://string-db.org/network/224308.BSU08290Two-component sensor histidine kinase [YfiK]; Required for resistance to linearmycins, a family of antibiotic-specialized metabolites produced by some streptomycetes. Member of the two-component [...]
yfiK protein networkhttps://string-db.org/network/224308.BSU08300Two-component response regulator [YfiJ]; Required for resistance to linearmycins, a family of antibiotic-specialized metabolites produced by some streptomycetes. Member of the two-component regul [...]
yfiL protein networkhttps://string-db.org/network/224308.BSU08310Putative ABC transporter (ATP-binding protein); Required for resistance to linearmycins, a family of antibiotic-specialized metabolites produced by some streptomycetes. Part of the ABC transporte [...]
yfiM protein networkhttps://string-db.org/network/224308.BSU08320Putative ABC transporter (permease); Required for resistance to linearmycins, a family of antibiotic-specialized metabolites produced by some streptomycetes. Part of the ABC transporter complex L [...]
yfiN protein networkhttps://string-db.org/network/224308.BSU08330Putative ABC transporter (permease); Required for resistance to linearmycins, a family of antibiotic-specialized metabolites produced by some streptomycetes. Part of the ABC transporter complex L [...]
padR protein networkhttps://string-db.org/network/224308.BSU08340Transcriptional regulator of PadC; Negative transcriptional regulator of padC phenolic acid decarboxylase.
estB protein networkhttps://string-db.org/network/224308.BSU08350Secreted esterase / lipase; An esterase which preferentially hydrolyzes triacylglyceride substrates with short chain fatty acids (less than C10) with the maximum activity towards tricaprylin (C8: [...]
yfiQ protein networkhttps://string-db.org/network/224308.BSU08360Putative membrane component involved in biofilm formation; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: [...]
yfiR protein networkhttps://string-db.org/network/224308.BSU08370Transcriptional regulator (TetR/AcrR family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
yfiS protein networkhttps://string-db.org/network/224308.BSU08380Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
bst protein networkhttps://string-db.org/network/224308.BSU08390Bacillithiol S-transferase; Possible metal-dependent hydrolase; Belongs to the metal hydrolase YfiT family.
yfiU protein networkhttps://string-db.org/network/224308.BSU08400Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yfiV protein networkhttps://string-db.org/network/224308.BSU08410Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
mprF protein networkhttps://string-db.org/network/224308.BSU08425Phosphatidylglycerol lysyltransferase involved in lysinylation of phospholipids; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which [...]
yfiY protein networkhttps://string-db.org/network/224308.BSU08440Putative iron(III) dicitrate transporter binding lipoprotein; Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin [...]
yfiZ protein networkhttps://string-db.org/network/224308.BSU08450iron(III) siderophore transport permease; Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen.
yfhA protein networkhttps://string-db.org/network/224308.BSU08460iron(III) siderophore transport permease; Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen.
yfhB protein networkhttps://string-db.org/network/224308.BSU08470Putative isomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the PhzF fa [...]
yfhC protein networkhttps://string-db.org/network/224308.BSU08480Putative oxidoreductase (nitroreductase family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yfhD protein networkhttps://string-db.org/network/224308.BSU08490Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yfhE protein networkhttps://string-db.org/network/224308.BSU08500Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yfhF protein networkhttps://string-db.org/network/224308.BSU08510Putative nucleotide binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belon [...]
recX protein networkhttps://string-db.org/network/224308.BSU08520Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
yfhH protein networkhttps://string-db.org/network/224308.BSU08530Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yfhI protein networkhttps://string-db.org/network/224308.BSU08540Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
sspK protein networkhttps://string-db.org/network/224308.BSU08550Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process; Belongs to the SspK family.
yfhJ protein networkhttps://string-db.org/network/224308.BSU08560Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yfhK protein networkhttps://string-db.org/network/224308.BSU08570Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yfhL protein networkhttps://string-db.org/network/224308.BSU08580SdpC immunity factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
yfhM protein networkhttps://string-db.org/network/224308.BSU08590Epoxide hydrolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
csbB protein networkhttps://string-db.org/network/224308.BSU08600Putative glycosyl transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to [...]
yfhO protein networkhttps://string-db.org/network/224308.BSU08610Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yfhP protein networkhttps://string-db.org/network/224308.BSU08620Putative membrane hydrolase; May act as a negative regulator for the transcription of mutY, fabL, sspE and yfhP.
mutY protein networkhttps://string-db.org/network/224308.BSU08630A/G-specific adenine glycosylase or DNA-(apurinic or apyrimidinic site) lyase; Base excision repair (BER) glycosylase that initiates repair of A:oxoG to C:G by removing the inappropriately paired [...]
yfhS protein networkhttps://string-db.org/network/224308.BSU08640Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10463184.
fabL protein networkhttps://string-db.org/network/224308.BSU08650Enoyl-acyl carrier protein reductase III; Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). It confers resistan [...]
sspE protein networkhttps://string-db.org/network/224308.BSU08660Small acid-soluble spore protein (gamma-type SASP); SASP are proteins degraded in the first minutes of spore germination and provide amino acids for both new protein synthesis and metabolism. The [...]
ygaB protein networkhttps://string-db.org/network/224308.BSU08670Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ygaC protein networkhttps://string-db.org/network/224308.BSU08680Putative factor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the UPF0374 family.
ygaD protein networkhttps://string-db.org/network/224308.BSU08690Putative ABC transporter (ATP-binding protein); May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible f [...]
ygaE protein networkhttps://string-db.org/network/224308.BSU08700Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
gsaB protein networkhttps://string-db.org/network/224308.BSU08710Glutamate-1-semialdehyde aminotransferase, class III aminotransferase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme.
ygaF protein networkhttps://string-db.org/network/224308.BSU08720Putative bacterioferritin comigratory protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a [...]
perR protein networkhttps://string-db.org/network/224308.BSU08730Transcriptional regulator (Fur family); Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis ope [...]
ygzB protein networkhttps://string-db.org/network/224308.BSU08740Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
ygxA protein networkhttps://string-db.org/network/224308.BSU08750Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
spo0M protein networkhttps://string-db.org/network/224308.BSU08760Sporulation-control gene; Controls the expression of spo0A and is required to pass the morphological stage 0 of sporulation; Belongs to the spo0M family.
ygzA protein networkhttps://string-db.org/network/224308.BSU08770Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ygzC protein networkhttps://string-db.org/network/224308.BSU08779Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ygaJ protein networkhttps://string-db.org/network/224308.BSU08780Putative peptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the peptida [...]
thiC protein networkhttps://string-db.org/network/224308.BSU08790Biosynthesis of the pyrimidine moiety from 5-aminoimidazole ribotide (AIR) (thiamin biosynthesis); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from [...]
ygaK protein networkhttps://string-db.org/network/224308.BSU08800Putative FAD-dependent oxido-reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
senS protein networkhttps://string-db.org/network/224308.BSU08810Transcriptional regulator (activator); Regulates the expression of extracellular-protein genes of Bacillus subtilis.
katA protein networkhttps://string-db.org/network/224308.BSU08820Vegetative catalase 1; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
ssuB protein networkhttps://string-db.org/network/224308.BSU08830Aliphatic sulfonate ABC transporter (ATP-binding protein); Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport sys [...]
ssuA protein networkhttps://string-db.org/network/224308.BSU08840Aliphatic sulfonate ABC transporter (binding lipoprotein); Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein.
ssuC protein networkhttps://string-db.org/network/224308.BSU08850Aliphatic sulfonate ABC transporter (permease); Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across t [...]
ssuD protein networkhttps://string-db.org/network/224308.BSU08860FMNH2-dependent aliphatic sulfonate monooxygenase; Catalyzes the desulfonation of aliphatic sulfonates.
ygaN protein networkhttps://string-db.org/network/224308.BSU08870Putative sulfur-related oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
rpsNB protein networkhttps://string-db.org/network/224308.BSU08880Alternative ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs t [...]
ygaO protein networkhttps://string-db.org/network/224308.BSU08890Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ygzD protein networkhttps://string-db.org/network/224308.BSU08899Putative HTH-type transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regul [...]
yhzB protein networkhttps://string-db.org/network/224308.BSU08900Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
queG protein networkhttps://string-db.org/network/224308.BSU08910Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA [...]
yhbB protein networkhttps://string-db.org/network/224308.BSU08920Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
trmL protein networkhttps://string-db.org/network/224308.BSU08930tRNA (cytidine(34)-2'-O)-methyltransferase TrmL; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. R [...]
yhbD protein networkhttps://string-db.org/network/224308.BSU08940Putative nucleic acid binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
yhbE protein networkhttps://string-db.org/network/224308.BSU08950Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yhbF protein networkhttps://string-db.org/network/224308.BSU08960Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
prkA protein networkhttps://string-db.org/network/224308.BSU08970Serine protein kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the PrkA family.
yhbH protein networkhttps://string-db.org/network/224308.BSU08980Factor involved in shape determination (sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
yhbI protein networkhttps://string-db.org/network/224308.BSU08990Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
yhbJ protein networkhttps://string-db.org/network/224308.BSU09000Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane compo [...]
yhcA protein networkhttps://string-db.org/network/224308.BSU09010Putative exporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yhcB protein networkhttps://string-db.org/network/224308.BSU09020NADH:quinone oxidoreductase associated to stress; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
yhcC protein networkhttps://string-db.org/network/224308.BSU09030Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yhcD protein networkhttps://string-db.org/network/224308.BSU09040Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yhcE protein networkhttps://string-db.org/network/224308.BSU09050Putative integral inner membrane orphan protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative m [...]
yhcF protein networkhttps://string-db.org/network/224308.BSU09060Putative transcriptional regulator (GntR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
yhcG protein networkhttps://string-db.org/network/224308.BSU09070Putative ABC transporter ATP-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs [...]
yhcH protein networkhttps://string-db.org/network/224308.BSU09080Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative tr [...]
yhcI protein networkhttps://string-db.org/network/224308.BSU09090Putative ABC transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
cspB protein networkhttps://string-db.org/network/224308.BSU09100Major cold-shock protein, RNA helicase co-factor, RNA co-chaperone; Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA, and also to other sequences. Has [...]
yhcJ protein networkhttps://string-db.org/network/224308.BSU09110Putative ABC transporter (binding lipoprotein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein [...]
yhcK protein networkhttps://string-db.org/network/224308.BSU09120Putative diguanylate cyclase or phosphodiesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative [...]
tcyP protein networkhttps://string-db.org/network/224308.BSU09130Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids a [...]
yhcM protein networkhttps://string-db.org/network/224308.BSU09140Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yhcN protein networkhttps://string-db.org/network/224308.BSU09150Putative lipoprotein; Probably contributes, directly or indirectly, to early events in germination. May play a role in spore outgrowth.
yhcO protein networkhttps://string-db.org/network/224308.BSU09165Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yhcQ protein networkhttps://string-db.org/network/224308.BSU09180Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yhcR protein networkhttps://string-db.org/network/224308.BSU09190Non specific extracellular endonuclease cleaving RNA and DNA; Sugar-nonspecific endonuclease that yields nucleotide 3'- monophosphate products. No 5'-nucleotidase activity was detected, using 5'- [...]
srtA protein networkhttps://string-db.org/network/224308.BSU09200Sortase A; Transpeptidase that anchors surface proteins to the cell wall. Recognizes and modifies its substrate by proteolytic cleavage of a C-terminal sorting signal. Following cleavage, a coval [...]
yhcT protein networkhttps://string-db.org/network/224308.BSU09210Putative RNA pseudouridine synthase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yhcU protein networkhttps://string-db.org/network/224308.BSU09220Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yhcV protein networkhttps://string-db.org/network/224308.BSU09230Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
glpW protein networkhttps://string-db.org/network/224308.BSU09240Glycerol-3-phosphate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type pe: putative enzyme.
yhcX protein networkhttps://string-db.org/network/224308.BSU09250Putative amidohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the ca [...]
yhxA protein networkhttps://string-db.org/network/224308.BSU09260Hypothetical protein; Essential for glycerol catabolism; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
glpP protein networkhttps://string-db.org/network/224308.BSU09270Glycerol-3-phosphate responding transcription antiterminator; Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glp [...]
glpF protein networkhttps://string-db.org/network/224308.BSU09280Glycerol permease; Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane; Belongs to [...]
glpK protein networkhttps://string-db.org/network/224308.BSU09290Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
glpD protein networkhttps://string-db.org/network/224308.BSU09300Glycerol-3-phosphate oxidase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
pgcA protein networkhttps://string-db.org/network/224308.BSU09310Alpha-phosphoglucomutase; Catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DA [...]
yhcY protein networkhttps://string-db.org/network/224308.BSU09320Two-component sensor histidine kinase [YhcZ]; Member of the two-component regulatory system YhcY/YhcZ. Probably activates YhcZ by phosphorylation.
yhcZ protein networkhttps://string-db.org/network/224308.BSU09330Two-component response regulator [YhcY]; Member of the two-component regulatory system YhcY/YhcZ.
yhdA protein networkhttps://string-db.org/network/224308.BSU09340Oxidoreductase, NAD(P)H-FMN and ferric iron reductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH, but not NADH, as an elec [...]
yhdB protein networkhttps://string-db.org/network/224308.BSU09350Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yhdC protein networkhttps://string-db.org/network/224308.BSU09360Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
lytF protein networkhttps://string-db.org/network/224308.BSU09370gamma-D-glutamate-meso-diaminopimelate muropeptidase (major autolysin); Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan. LytF is necessary and suff [...]
nsrR protein networkhttps://string-db.org/network/224308.BSU09380NO-dependent activator of the ResDE regulon; Nitric oxide-responsive transcriptional regulator. It represses the expression of flavohemoprotein hmp and the nitrite reductase nasD. Probably plays [...]
ygxB protein networkhttps://string-db.org/network/224308.BSU09390Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
spoVR protein networkhttps://string-db.org/network/224308.BSU09400Involved in spore cortex synthesis (stage V sporulation); Appears to be involved in spore cortex formation.
phoA protein networkhttps://string-db.org/network/224308.BSU09410Alkaline phosphatase A; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the alkaline phosphatase family.
lytE protein networkhttps://string-db.org/network/224308.BSU09420Cell wall hydrolase; Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan (By similarity). Seems to play a role in cell separation during vegetative gro [...]
citR protein networkhttps://string-db.org/network/224308.BSU09430Transcriptional regulator CitR (LysR family); Negative regulatory protein for the citA gene for citrate synthase I; Belongs to the LysR transcriptional regulatory family.
citA protein networkhttps://string-db.org/network/224308.BSU09440Citrate synthase I; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect; Belongs to the citrate s [...]
yhdF protein networkhttps://string-db.org/network/224308.BSU09450Putative NAD(P)-dependent dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the sho [...]
bcaP protein networkhttps://string-db.org/network/224308.BSU09460Branched-chain amino acid transporter; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter; Belongs to the amino acid-polyamine-organocation (APC) [...]
yhdH protein networkhttps://string-db.org/network/224308.BSU09470Putative sodium-dependent transporter; Putative sodium-dependent transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
yhdI protein networkhttps://string-db.org/network/224308.BSU09480Putative PLP-dependent transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
yhdJ protein networkhttps://string-db.org/network/224308.BSU09490Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the acetyltransferas [...]
yhdK protein networkhttps://string-db.org/network/224308.BSU09500Negative regulator of the activity of sigma-M; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type ph: phenotype.
yhdL protein networkhttps://string-db.org/network/224308.BSU09510Negative regulator of the activity of sigma-M; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type ph: phenotype.
sigM protein networkhttps://string-db.org/network/224308.BSU09520RNA polymerase ECF (extracytoplasmic function)-type sigma factor (sigma(M)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and ar [...]
yhdN protein networkhttps://string-db.org/network/224308.BSU09530Aldo/keto reductase specific for NADPH; Aldo-keto reductase (AKR) that displays broad substrate specificity in vitro. Is able to reduce the standard AKR substrates DL- glyceraldehyde, D-erythrose [...]
plsC protein networkhttps://string-db.org/network/224308.BSU095401-acylglycerol-phosphate (1-acyl-G3P) acyltransferase; Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acy [...]
yhdP protein networkhttps://string-db.org/network/224308.BSU09550Putative transporter or sensor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
cueR protein networkhttps://string-db.org/network/224308.BSU09560Copper efflux transcriptional regulator; Transcriptional activator of the copZA operon.
yhdR protein networkhttps://string-db.org/network/224308.BSU09570Putative aspartate aminotransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yhdT protein networkhttps://string-db.org/network/224308.BSU09590Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
crcBA protein networkhttps://string-db.org/network/224308.BSU09600Integral membrane protein possibly involved in chromosome condensation; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) fami [...]
yhdV protein networkhttps://string-db.org/network/224308.BSU09610Integral membrane protein possibly involved in chromosome condensation; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) fami [...]
yhdW protein networkhttps://string-db.org/network/224308.BSU09620Putative glycerophosphodiester phosphodiesterase; Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to sn-glycerol 3-phosphate (G3P) and the corresponding alcohols.
yhdX protein networkhttps://string-db.org/network/224308.BSU09630Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yhdY protein networkhttps://string-db.org/network/224308.BSU09640Putative integral membrane protein; May play a role in resistance to osmotic downshock.
srtN protein networkhttps://string-db.org/network/224308.BSU09650Sirtuin NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. [...]
yheN protein networkhttps://string-db.org/network/224308.BSU09660Putative polysaccharide deacetylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
dat protein networkhttps://string-db.org/network/224308.BSU09670D-alanine aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino [...]
nhaC protein networkhttps://string-db.org/network/224308.BSU09680Na+/H+ antiporter; Is a secondary, electrogenic Na(+)/H(+) antiporter that catalyzes Na(+) uptake and proton efflux. Makes modest contributions to pH homeostasis in the alkaline range of pH but i [...]
nhaX protein networkhttps://string-db.org/network/224308.BSU09690Stress response protein, UspA family; Evidence 2b: Function of strongly homologous gene; factor.
yheJ protein networkhttps://string-db.org/network/224308.BSU09700Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yheI protein networkhttps://string-db.org/network/224308.BSU09710Probable multidrug resistance ABC transporter ATP-binding/permease protein YheI; Involved in the transport of four structurally unrelated drugs, including doxorubicin and mitoxantrone. Transmembr [...]
yheH protein networkhttps://string-db.org/network/224308.BSU09720Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH; Involved in the transport of four structurally unrelated drugs, including doxorubicin and mitoxantrone. Transmembr [...]
yheG protein networkhttps://string-db.org/network/224308.BSU09730Putative NADH-flavin oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yheF protein networkhttps://string-db.org/network/224308.BSU09740Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
sspB protein networkhttps://string-db.org/network/224308.BSU09750Small acid-soluble spore protein (beta-type SASP); SASP are bound to spore DNA. They are double-stranded DNA- binding proteins that cause DNA to change to an a-like conformation. They protect the [...]
yheE protein networkhttps://string-db.org/network/224308.BSU09760Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yheD protein networkhttps://string-db.org/network/224308.BSU09770Spore coat associated protein; Involved in sporulation.
yheC protein networkhttps://string-db.org/network/224308.BSU09780Spore coat associated protein, similar to YheD; Involved in sporulation; Belongs to the YheC/YheD family.
yheB protein networkhttps://string-db.org/network/224308.BSU09790Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16684363.
yheA protein networkhttps://string-db.org/network/224308.BSU09800Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 19429628; Belongs to the UPF0342 family.
yhaZ protein networkhttps://string-db.org/network/224308.BSU09810Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16267290.
yhaX protein networkhttps://string-db.org/network/224308.BSU09830Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
hemZ protein networkhttps://string-db.org/network/224308.BSU09840Coproporphyrinogen III oxidase; Involved in the biosynthesis of porphyrin-containing compound; Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemZ subfamily.
yhaU protein networkhttps://string-db.org/network/224308.BSU09850Transporter involved in K+ efflux; Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Can also mediate rubidium/proton antiport, but has no permeability for sod [...]
khtT protein networkhttps://string-db.org/network/224308.BSU09860K+/H+ antiporter for K+ efflux; Required for activity of the potassium/proton antiporter KhtU. Involved in protection of the cell from methylglyoxal, a toxic by-product of glycolysis.
khtS protein networkhttps://string-db.org/network/224308.BSU09870K+/H+ antiporter for K+ efflux; Modulates the activity of the potassium/proton antiporter KhtU. Involved in protection of the cell from methylglyoxal, a toxic by-product of glycolysis.
yhaR protein networkhttps://string-db.org/network/224308.BSU09880Putative dehydratase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yhzD protein networkhttps://string-db.org/network/224308.BSU09889Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yhaQ protein networkhttps://string-db.org/network/224308.BSU09890Na+-efflux ABC transporter (ATP-binding protein); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; transporter.
yhaP protein networkhttps://string-db.org/network/224308.BSU09900Na+ exporter (ABC permease); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t: transporter; To M.jannaschii MJ1024.
yhaO protein networkhttps://string-db.org/network/224308.BSU09910Putative exonuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the metallophosphoesterase [...]
sbcE protein networkhttps://string-db.org/network/224308.BSU09920ATPase involved in DNA double strand break repair and recombination; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
yhaM protein networkhttps://string-db.org/network/224308.BSU099303'-5' exonuclease; Shows a 3'-5' exoribonuclease activity as well as single- stranded DNA 3'-5'exonuclease activity. Plays a role in the secondary pathway of 23S rRNA 3' end maturation; Belongs t [...]
yhaL protein networkhttps://string-db.org/network/224308.BSU09940Sporulation factor; Required for efficient sporulation.
prsA protein networkhttps://string-db.org/network/224308.BSU09950Molecular chaperone lipoprotein; Essential protein that plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. Has PPIase [...]
sscA protein networkhttps://string-db.org/network/224308.BSU09958Spore assembly and germination protein; Spore protein involved in the assembly of several components of the spore coat, including CotB, CotG and CotH, and in spore germination.
sscB protein networkhttps://string-db.org/network/224308.BSU09959Spore and germination protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
yhaJ protein networkhttps://string-db.org/network/224308.BSU09965Putative bacteriocin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
yhaI protein networkhttps://string-db.org/network/224308.BSU09980Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
scoC protein networkhttps://string-db.org/network/224308.BSU09990HTH-type transcriptional regulator Hpr; Negative regulator of protease production and sporulation. Acts by binding directly to the promoter of protease genes (aprE and nprE), and by repressing ol [...]
yhaH protein networkhttps://string-db.org/network/224308.BSU10000Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
yhzF protein networkhttps://string-db.org/network/224308.BSU10009Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
trpP protein networkhttps://string-db.org/network/224308.BSU10010Tryptophan transporter; Probably involved in tryptophan uptake; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. TrpP subfamily.
serC protein networkhttps://string-db.org/network/224308.BSU10020Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belon [...]
hinT protein networkhttps://string-db.org/network/224308.BSU10030Hit-family hydrolase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.
ecsA protein networkhttps://string-db.org/network/224308.BSU10040ABC transporter (ATP-binding protein); Has a role in exoprotein production, sporulation and competence.
ecsB protein networkhttps://string-db.org/network/224308.BSU10050ABC transporter (membrane protein); Presumed to form part of an ABC-transporter, it may form a transport channel.
ecsC protein networkhttps://string-db.org/network/224308.BSU10060Putative hydrolase; Unknown, does not resemble components of ABC transporters.
yhaA protein networkhttps://string-db.org/network/224308.BSU10070Putative amidohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yhfA protein networkhttps://string-db.org/network/224308.BSU10080Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yhgB protein networkhttps://string-db.org/network/224308.BSU10090Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
hmoB protein networkhttps://string-db.org/network/224308.BSU10100Heme-degrading monooxygenase; Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 r [...]
pbpF protein networkhttps://string-db.org/network/224308.BSU10110Penicillin-binding protein 2C required for spore germination; Cell wall formation. May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall [...]
hemE protein networkhttps://string-db.org/network/224308.BSU10120Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
hemH protein networkhttps://string-db.org/network/224308.BSU10130Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family.
hemY protein networkhttps://string-db.org/network/224308.BSU10140Protoporphyrinogen IX and coproporphyrinogen III oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. Also oxidizes the pathway intermediate coproporphy [...]
yhgD protein networkhttps://string-db.org/network/224308.BSU10150Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
yhgE protein networkhttps://string-db.org/network/224308.BSU10160Putative methyl-accepting protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
fabHB protein networkhttps://string-db.org/network/224308.BSU10170Beta-ketoacyl-acyl carrier protein synthase III 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the f [...]
yhfC protein networkhttps://string-db.org/network/224308.BSU10180Putative integral membrane protein, putative chaperone; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: put [...]
yhfE protein networkhttps://string-db.org/network/224308.BSU10200Putative endoglucanase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yhfF protein networkhttps://string-db.org/network/224308.BSU10210Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
gltT protein networkhttps://string-db.org/network/224308.BSU10220Proton/sodium-glutamate symport protein; This carrier protein is part of the Na(+)-dependent, binding- protein-independent glutamate-aspartate transport system.
yhfH protein networkhttps://string-db.org/network/224308.BSU10230Hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yhfI protein networkhttps://string-db.org/network/224308.BSU10240Putative metal-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
lplJ protein networkhttps://string-db.org/network/224308.BSU10250Lipoate-protein ligase; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-depen [...]
yhfK protein networkhttps://string-db.org/network/224308.BSU10260Putative epimerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
lcfB protein networkhttps://string-db.org/network/224308.BSU10270Long-chain fatty-acid-CoA ligase (degradative); Involved in the degradation of long-chain fatty acids; Belongs to the ATP-dependent AMP-binding enzyme family.
yhfM protein networkhttps://string-db.org/network/224308.BSU10280Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yhfN protein networkhttps://string-db.org/network/224308.BSU10290Putative membrane metalloprotease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
aprE protein networkhttps://string-db.org/network/224308.BSU10300Serine alkaline protease (subtilisin E); Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides; Belongs to the peptidase S8 family.
yhfO protein networkhttps://string-db.org/network/224308.BSU10310Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
yhfP protein networkhttps://string-db.org/network/224308.BSU10320Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the zi [...]
yhfQ protein networkhttps://string-db.org/network/224308.BSU10330Putative iron(III) dicitrate-binding lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belo [...]
phoE protein networkhttps://string-db.org/network/224308.BSU10340Phosphatase; Phosphatase with broad substrate specificity. Does not have phosphoglycerate mutase activity; Belongs to the phosphoglycerate mutase family. GpmB subfamily.
yhfS protein networkhttps://string-db.org/network/224308.BSU10350Putative acetyl-CoA C-acetyltransferase; May be involved in fatty acid metabolism; Belongs to the thiolase-like superfamily. Thiolase family.
yhfT protein networkhttps://string-db.org/network/224308.BSU10360Putative long-chain fatty-acid-CoA ligase; May be involved in fatty acid metabolism; Belongs to the ATP-dependent AMP-binding enzyme family.
bioY protein networkhttps://string-db.org/network/224308.BSU10370Biotin transporter; Probable biotin transporter.
hemAT protein networkhttps://string-db.org/network/224308.BSU10380Haem-based dioxygen sensor; Heme-containing signal transducer responsible for aerotaxis, the migratory response toward or away from oxygen.
yhfW protein networkhttps://string-db.org/network/224308.BSU10390Putative Rieske [2Fe-2S] oxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yhxC protein networkhttps://string-db.org/network/224308.BSU10400Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the sh [...]
yhzC protein networkhttps://string-db.org/network/224308.BSU10410Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
comK protein networkhttps://string-db.org/network/224308.BSU10420Competence transcription factor (CTF); A master regulator required for the expression of late competence genes including comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and pos [...]
yhxD protein networkhttps://string-db.org/network/224308.BSU10430Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the sh [...]
yhjA protein networkhttps://string-db.org/network/224308.BSU10440Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yhjB protein networkhttps://string-db.org/network/224308.BSU10450Putative Na+/metabolite cotransporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter [...]
yhjC protein networkhttps://string-db.org/network/224308.BSU10460Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
yhjD protein networkhttps://string-db.org/network/224308.BSU10470Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16267290.
yhjE protein networkhttps://string-db.org/network/224308.BSU10480Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
sipV protein networkhttps://string-db.org/network/224308.BSU10490Type I signal peptidase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the peptidase S26 family.
yhjG protein networkhttps://string-db.org/network/224308.BSU10500Putative aromatic compound monooxygenase/hydroxylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putat [...]
yhjH protein networkhttps://string-db.org/network/224308.BSU10510Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
glcP protein networkhttps://string-db.org/network/224308.BSU10520glucose/mannose:H+ symporter; Can transport glucose, mannose, 2-deoxyglucose and methyl alpha-glucoside, but not galactose.
ntdC protein networkhttps://string-db.org/network/224308.BSU10530Biosynthesis of neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha,beta-trehalose), dehydrogenase; Involved in the biosynthesis of kanosamine (3-amino-3-deoxy- D-glucose), which is known to hav [...]
ntdB protein networkhttps://string-db.org/network/224308.BSU10540Biosynthesis of neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha, beta-trehalose);hydrolase; Involved in the biosynthesis of kanosamine (3-amino-3-deoxy- D-glucose), which is known to have an [...]
ntdA protein networkhttps://string-db.org/network/224308.BSU105503-oxo-glucose-6-phosphate:glutamate aminotransferase; Involved in the biosynthesis of kanosamine (3-amino-3-deoxy- D-glucose), which is known to have antibiotic and antifungal properties, and to [...]
yhjM protein networkhttps://string-db.org/network/224308.BSU10560Transcriptional regulator of the ntd operon; Positively regulates the ntdABC operon and negatively regulates its own transcription. Binds to NTD to induce ntdABC transcription.
yhjN protein networkhttps://string-db.org/network/224308.BSU10570Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yhjO protein networkhttps://string-db.org/network/224308.BSU10580Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yhjP protein networkhttps://string-db.org/network/224308.BSU10590Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; In the C-terminal section; belongs to the bacterial solute- binding protein 5 family.
yhjQ protein networkhttps://string-db.org/network/224308.BSU10600Putative ferredoxin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc: putative carrier.
yhjR protein networkhttps://string-db.org/network/224308.BSU10610Putative electron carrier protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc: putative carrier.
addB protein networkhttps://string-db.org/network/224308.BSU10620ATP-dependent deoxyribonuclease (subunit B); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent single-stranded exonuclease, acting in both directions. Recognizes the [...]
addA protein networkhttps://string-db.org/network/224308.BSU10630ATP-dependent deoxyribonuclease (subunit A); An essential component of the DNA double-stranded break repair machinery, the heterodimer acts as both an ATP-dependent DNA helicase and an ATP-depend [...]
sbcD protein networkhttps://string-db.org/network/224308.BSU10640DNA repair exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'-> [...]
sbcC protein networkhttps://string-db.org/network/224308.BSU10650DNA ATP-dependent repair enzyme; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts [...]
yisB protein networkhttps://string-db.org/network/224308.BSU10660Putative nuclease component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
gerPF protein networkhttps://string-db.org/network/224308.BSU10670Spore germination protein; Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the ac [...]
gerPE protein networkhttps://string-db.org/network/224308.BSU10680Spore germination protein; Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the ac [...]
gerPD protein networkhttps://string-db.org/network/224308.BSU10690Spore germination protein; Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the ac [...]
gerPC protein networkhttps://string-db.org/network/224308.BSU10700Spore germination protein; Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the ac [...]
gerPB protein networkhttps://string-db.org/network/224308.BSU10710Spore germination protein; Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the ac [...]
gerPA protein networkhttps://string-db.org/network/224308.BSU10720Spore germination protein; Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the ac [...]
yisI protein networkhttps://string-db.org/network/224308.BSU10730Spo0A-P phosphatase; Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in [...]
yisJ protein networkhttps://string-db.org/network/224308.BSU10740Putative spore coat protein; Involved in the assembly of several proteins in the inner and outer layer of the spore coat; Belongs to the CotH family.
yisK protein networkhttps://string-db.org/network/224308.BSU10750Putative catabolic enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yisL protein networkhttps://string-db.org/network/224308.BSU10760Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane compo [...]
wprA protein networkhttps://string-db.org/network/224308.BSU10770Cell wall-associated protease; CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges; Belongs to the peptidase S8 family.
yisN protein networkhttps://string-db.org/network/224308.BSU10780Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
asnO protein networkhttps://string-db.org/network/224308.BSU10790Asparagine synthetase; Asparagine synthetase involved in sporulation.
yizA protein networkhttps://string-db.org/network/224308.BSU10800Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DinB family.
yisP protein networkhttps://string-db.org/network/224308.BSU10810Putative squalene/phytoene synthase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belon [...]
yisQ protein networkhttps://string-db.org/network/224308.BSU10820Putative Na+driven efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter [...]
yisR protein networkhttps://string-db.org/network/224308.BSU10830Putative transcriptional regulator (AraC/XylS family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
degA protein networkhttps://string-db.org/network/224308.BSU10840Transcriptional regulator (LacI family); Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease.
yisS protein networkhttps://string-db.org/network/224308.BSU10850Putative myo-inositol 2-dehydrogenase; Catalyzes the reversible NAD(+)-dependent oxidation of scyllo-inositol (SI) to 2,4,6/3,5-pentahydroxycyclohexanone (scyllo- inosose or SIS). Is required for [...]
yisT protein networkhttps://string-db.org/network/224308.BSU10860Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DinB family.
yisU protein networkhttps://string-db.org/network/224308.BSU10870Putative aminoacid related metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: p [...]
yisV protein networkhttps://string-db.org/network/224308.BSU10880Putative PLP-dependent transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
yisX protein networkhttps://string-db.org/network/224308.BSU10890Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yisY protein networkhttps://string-db.org/network/224308.BSU10900Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the AB hydr [...]
yisZ protein networkhttps://string-db.org/network/224308.BSU10910Putative adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
yitA protein networkhttps://string-db.org/network/224308.BSU10920Putative sulfate adenylyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the sulfat [...]
yitB protein networkhttps://string-db.org/network/224308.BSU10930Putative phospho-adenylylsulfate sulfotransferase; Reduction of activated sulfate into sulfite; Belongs to the PAPS reductase family. CysH subfamily.
slpH protein networkhttps://string-db.org/network/224308.BSU109402-phosphosulfolactate phosphatase; Evidence 2b: Function of strongly homologous gene; enzyme; Belongs to the ComB family.
slpS protein networkhttps://string-db.org/network/224308.BSU10950Phosphosulfolactate synthase; Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL) (By similarity). Is probably involved in the biosynthesis o [...]
yitE protein networkhttps://string-db.org/network/224308.BSU10960Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yitF protein networkhttps://string-db.org/network/224308.BSU10970Putative enolase superfamily enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belon [...]
yitG protein networkhttps://string-db.org/network/224308.BSU10980Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yitH protein networkhttps://string-db.org/network/224308.BSU10990Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
yitI protein networkhttps://string-db.org/network/224308.BSU11000Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
samT protein networkhttps://string-db.org/network/224308.BSU11010Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.
yitK protein networkhttps://string-db.org/network/224308.BSU11020Putative RNA binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the UPF0234 family [...]
yitL protein networkhttps://string-db.org/network/224308.BSU11030RNA-binding protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.
yitM protein networkhttps://string-db.org/network/224308.BSU11040Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yitO protein networkhttps://string-db.org/network/224308.BSU11055Putative integral inner membrane protein with HTTM domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: [...]
yitP protein networkhttps://string-db.org/network/224308.BSU11070Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 6289325.
yizB protein networkhttps://string-db.org/network/224308.BSU11079Putative DNA/RNA binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
yitQ protein networkhttps://string-db.org/network/224308.BSU11080Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yitR protein networkhttps://string-db.org/network/224308.BSU11090Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
nprB protein networkhttps://string-db.org/network/224308.BSU11100Extracellular neutral protease B; Protease able to cleave casein in vitro. Belongs to the peptidase M4 family.
yitS protein networkhttps://string-db.org/network/224308.BSU11110Conserved hypothetical protein; May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
yitT protein networkhttps://string-db.org/network/224308.BSU11120Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ipi protein networkhttps://string-db.org/network/224308.BSU11130Intracellular proteinase inhibitor BsuPI; Directly regulates the major intracellular proteinase (ISP-1) activity in vivo. Inhibits ISP-1 in the early stages of sporulation. It may be then inactiv [...]
yizC protein networkhttps://string-db.org/network/224308.BSU11139Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yitU protein networkhttps://string-db.org/network/224308.BSU11140Putative phosphatase; Catalyzes the dephosphorylation of the riboflavin precursor 5-amino-6-(5-phospho-D-ribitylamino)uracil and of flavin mononucleotide (FMN) in vitro.
yitV protein networkhttps://string-db.org/network/224308.BSU11150Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yitW protein networkhttps://string-db.org/network/224308.BSU11160Conserved hypothetical protein; Involved in the maturation of iron-sulfur (Fe-S) proteins. May function as a Fe-S cluster carrier.
yitY protein networkhttps://string-db.org/network/224308.BSU11170Putative FMN/FAD-binding oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yitZ protein networkhttps://string-db.org/network/224308.BSU11180Putative transport protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
argC protein networkhttps://string-db.org/network/224308.BSU11190N-acetylglutamate gamma-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA de [...]
argJ protein networkhttps://string-db.org/network/224308.BSU11200Ornithine acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the ac [...]
argB protein networkhttps://string-db.org/network/224308.BSU11210N-acetylglutamate 5-phosphotransferase (acetylglutamate kinase); Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily [...]
argD protein networkhttps://string-db.org/network/224308.BSU11220N-acetylornithine aminotransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the class-III pyridoxal-phosphate [...]
carA protein networkhttps://string-db.org/network/224308.BSU11230Arginine-specific carbamoyl-phosphate synthetase (small subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
carB protein networkhttps://string-db.org/network/224308.BSU11240Arginine-specific carbamoyl-phosphate synthetase (large subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the CarB family.
argF protein networkhttps://string-db.org/network/224308.BSU11250Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs t [...]
yjzC protein networkhttps://string-db.org/network/224308.BSU11260Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjzD protein networkhttps://string-db.org/network/224308.BSU11270Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjaU protein networkhttps://string-db.org/network/224308.BSU11280Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjaV protein networkhttps://string-db.org/network/224308.BSU11290Putative NAD(P) binding enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
med protein networkhttps://string-db.org/network/224308.BSU11300Positive regulator of comK; Positive activator of the comK gene; Belongs to the BMP lipoprotein family.
comZ protein networkhttps://string-db.org/network/224308.BSU11310Putative late competence gene; Negatively regulates the transcription of the comG operon.
yjzB protein networkhttps://string-db.org/network/224308.BSU11320Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16391061.
fabHA protein networkhttps://string-db.org/network/224308.BSU11330Beta-ketoacyl-acyl carrier protein synthase III 1; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the f [...]
fabF protein networkhttps://string-db.org/network/224308.BSU11340Beta-ketoacyl-acyl carrier protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thi [...]
yjaZ protein networkhttps://string-db.org/network/224308.BSU11350Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
appD protein networkhttps://string-db.org/network/224308.BSU11360Oligopeptide ABC transporter (ATP-binding protein); This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitut [...]
appF protein networkhttps://string-db.org/network/224308.BSU11370Oligopeptide ABC transporter (ATP-binding protein); This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitut [...]
appB protein networkhttps://string-db.org/network/224308.BSU11390Oligopeptide ABC transporter (oligopeptide-binding lipoprotein); This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can complet [...]
appC protein networkhttps://string-db.org/network/224308.BSU11400Oligopeptide ABC transporter (permease); This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the O [...]
yjbA protein networkhttps://string-db.org/network/224308.BSU11410Putative nucleic acid binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Bel [...]
trpS protein networkhttps://string-db.org/network/224308.BSU11420tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
oppA protein networkhttps://string-db.org/network/224308.BSU11430Oligopeptide ABC transporter (binding lipoprotein); This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, It binds peptides up to five amino acid [...]
oppB protein networkhttps://string-db.org/network/224308.BSU11440Oligopeptide ABC transporter (permease); Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane. [...]
oppC protein networkhttps://string-db.org/network/224308.BSU11450Oligopeptide ABC transporter (permease); Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane. [...]
oppD protein networkhttps://string-db.org/network/224308.BSU11460Oligopeptide ABC transporter (ATP-binding protein); Part of the binding protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Req [...]
oppF protein networkhttps://string-db.org/network/224308.BSU11470Oligopeptide ABC transporter (ATP-binding protein); Component of the oligopeptide permease, a binding protein- dependent transport system. Necessary for genetic competence but not sporulation. Pr [...]
yjbB protein networkhttps://string-db.org/network/224308.BSU11480Putative exporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yjbC protein networkhttps://string-db.org/network/224308.BSU11490Putative thiol oxidation management factor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme [...]
spxA protein networkhttps://string-db.org/network/224308.BSU11500Redox-sensitive regulator enzyme; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes invol [...]
yjbE protein networkhttps://string-db.org/network/224308.BSU11510Putative transporter component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
mecA protein networkhttps://string-db.org/network/224308.BSU11520Adaptor protein controlling oligomerization of the AAA+ protein ClpC; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved [...]
coiA protein networkhttps://string-db.org/network/224308.BSU11530Protein involved in establishment of DNA transport in competence; Required for optimal transformation.
pepF protein networkhttps://string-db.org/network/224308.BSU11540Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
yizD protein networkhttps://string-db.org/network/224308.BSU11549Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjbH protein networkhttps://string-db.org/network/224308.BSU11550Putative thiol management oxidoreductase component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putativ [...]
yjbI protein networkhttps://string-db.org/network/224308.BSU11560Putative thiol management oxidoreductase component; Hemoglobin-like protein that exhibits a low peroxidase activity. Its very high oxygen affinity may rule out the possibility that it is involved [...]
yjbJ protein networkhttps://string-db.org/network/224308.BSU11570Putative murein lytic transglycosylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Be [...]
yjbK protein networkhttps://string-db.org/network/224308.BSU11580Putative RNA/thiamine triphosphatase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yjbL protein networkhttps://string-db.org/network/224308.BSU11590Putative phosphatase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the UPF07 [...]
relP protein networkhttps://string-db.org/network/224308.BSU11600(p)ppGpp synthetase; Functions as a (p)ppGpp synthase; GDP can be used instead of GTP, resulting in an increase of (p)ppGpp synthesis. The enzyme binds ATP, then GDP or GTP and catalysis is highl [...]
ppnKA protein networkhttps://string-db.org/network/224308.BSU11610Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosph [...]
yjbO protein networkhttps://string-db.org/network/224308.BSU11620Pseudouridylate synthase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme.
prpE protein networkhttps://string-db.org/network/224308.BSU11630Phosphorylated protein phosphatase E and diadenosine-polyphosphate hydrolase; Asymmetrically hydrolyzes Ap4p to yield AMP and ATP. Does not hydrolyze Ap2a or Ap6A. Also has an ATPase activity. Wa [...]
yjbQ protein networkhttps://string-db.org/network/224308.BSU11640Putative Na+/H+ antiporter; Probable Na(+)/H(+) antiporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
tenA protein networkhttps://string-db.org/network/224308.BSU11650Thiaminase II; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes [...]
tenI protein networkhttps://string-db.org/network/224308.BSU11660Thiazole tautomerase; Catalyzes the irreversible aromatization of 2-((2R,5Z)-2- carboxy-4-methylthiazol-5(2H)-ylidene)ethyl phosphate (cThz*-P) to 2- (2-carboxy-4-methylthiazol-5-yl)ethyl phospha [...]
thiO protein networkhttps://string-db.org/network/224308.BSU11670FAD-dependent glycine oxidase; Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha-keto acids, ammonia/amine, and hydrogen perox [...]
thiS protein networkhttps://string-db.org/network/224308.BSU11680Sulfur carrier for synthesis of hydroxyethylthiazole phosphate; Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate; Belongs to the sulfur carrier protein [...]
thiG protein networkhttps://string-db.org/network/224308.BSU11690Hydroxyethylthiazole phosphate synthetase (thiamine biosynthesis); Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur [...]
thiF protein networkhttps://string-db.org/network/224308.BSU11700Adenylate transferase and sulfur transferase (thiamine biosynthesis); Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS; Belongs to t [...]
thiD protein networkhttps://string-db.org/network/224308.BSU11710Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. Shows no activity with pyridoxal [...]
fabI protein networkhttps://string-db.org/network/224308.BSU11720Enoyl-acyl carrier protein reductase; Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongat [...]
cotO protein networkhttps://string-db.org/network/224308.BSU11730Spore outer coat protein; Has an important morphogenetic role. Involved in the assembly of at least five coat proteins, including CotB, CotG, CotS, CotSA and CotW. Required for appearance of a mo [...]
cotZ protein networkhttps://string-db.org/network/224308.BSU11740Spore coat protein (insoluble fraction, outermost layer); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
cotY protein networkhttps://string-db.org/network/224308.BSU11750Outer spore coat protein (insoluble fraction); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
cotX protein networkhttps://string-db.org/network/224308.BSU11760Spore coat protein (insoluble fraction); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
cotW protein networkhttps://string-db.org/network/224308.BSU11770Spore coat protein (insoluble fraction); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
cotV protein networkhttps://string-db.org/network/224308.BSU11780Spore coat protein (insoluble fraction); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
yjcA protein networkhttps://string-db.org/network/224308.BSU11790Sporulation-specific protein; Involved in sporulation.
yjzK protein networkhttps://string-db.org/network/224308.BSU11799Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjcZ protein networkhttps://string-db.org/network/224308.BSU11809Putative type I toxin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
spoVIF protein networkhttps://string-db.org/network/224308.BSU11810Sporulation-specific protein needed for heat resistance; Transcription factor involved in spore coat assembly and spore resistance. Regulates the transcription of at least cgeA, cotG and cotS.
yjcD protein networkhttps://string-db.org/network/224308.BSU11820Putative ATP-dependent DNA helicase; May be involved in the generation of recombinogenic substrates for the subsequent action of RecA.
yjzE protein networkhttps://string-db.org/network/224308.BSU11839Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 11976315.
yjcF protein networkhttps://string-db.org/network/224308.BSU11840Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the [...]
yjcG protein networkhttps://string-db.org/network/224308.BSU11850Putative RNA ligase or phosphoesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yjcH protein networkhttps://string-db.org/network/224308.BSU11860Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
metI protein networkhttps://string-db.org/network/224308.BSU11870Cystathionine gamma-synthase and O-acetylhomoserine thiolyase; Catalyzes the formation of L-cystathionine from O-acetyl-L- homoserine and L-cysteine. Cannot use O-succinyl-L-homoserine as substra [...]
metC protein networkhttps://string-db.org/network/224308.BSU11880Cystathionine beta-lyase; Catalyzes the transformation of cystathionine into homocysteine. Also exhibits cysteine desulfhydrase activity in vitro, producing sulfide from cysteine; Belongs to the [...]
yjcK protein networkhttps://string-db.org/network/224308.BSU11890Putative ribosomal-protein-alanine N-acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S5.
yjcL protein networkhttps://string-db.org/network/224308.BSU11900Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yjcM protein networkhttps://string-db.org/network/224308.BSU11910Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjcN protein networkhttps://string-db.org/network/224308.BSU11920Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjzF protein networkhttps://string-db.org/network/224308.BSU11928Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yjzG protein networkhttps://string-db.org/network/224308.BSU11929Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yjcO protein networkhttps://string-db.org/network/224308.BSU11930Putative DNA binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
yjcP protein networkhttps://string-db.org/network/224308.BSU11940Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535.
yjcQ protein networkhttps://string-db.org/network/224308.BSU11950Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535.
yjcR protein networkhttps://string-db.org/network/224308.BSU11960Putative phage-related nucleic acid binding terminase small subunit; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product [...]
yjcS protein networkhttps://string-db.org/network/224308.BSU11970Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjdA protein networkhttps://string-db.org/network/224308.BSU11980Putative acyl-carrier protein oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to th [...]
yjdB protein networkhttps://string-db.org/network/224308.BSU11990Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
manR protein networkhttps://string-db.org/network/224308.BSU12000Transcriptional antiterminator; Positively regulates the expression of the mannose operon that consists of three genes, manP, manA, and yjdF, which are responsible for the transport and utilizati [...]
manP protein networkhttps://string-db.org/network/224308.BSU12010Phosphotransferase system (PTS) mannose-specific enzyme IIBCA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport syst [...]
manA protein networkhttps://string-db.org/network/224308.BSU12020Mannose-6 phosphate isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the mannose-6-phosphate isomerase type 1 family.
yjdF protein networkhttps://string-db.org/network/224308.BSU12030Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 20139185.
yjdG protein networkhttps://string-db.org/network/224308.BSU12040Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the [...]
yjdH protein networkhttps://string-db.org/network/224308.BSU12050Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
trnE protein networkhttps://string-db.org/network/224308.BSU12060tRNA editing protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfa [...]
yjzH protein networkhttps://string-db.org/network/224308.BSU12069Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjdJ protein networkhttps://string-db.org/network/224308.BSU12070Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ctaO protein networkhttps://string-db.org/network/224308.BSU12080Minor protoheme IX farnesyltransferase 1 (heme O synthase); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl fa [...]
cotT protein networkhttps://string-db.org/network/224308.BSU12090Spore coat protein (inner coat); Inner spore coat protein which seems to play a role in germination.
pdaC protein networkhttps://string-db.org/network/224308.BSU12100N-acetylmuramic acid deacetylase; Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in peptidoglycan, a modification that confers resistance to lysosyme. Is not able to deacet [...]
yjfA protein networkhttps://string-db.org/network/224308.BSU12110Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjfB protein networkhttps://string-db.org/network/224308.BSU12120Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535.
yjfC protein networkhttps://string-db.org/network/224308.BSU12130Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjgA protein networkhttps://string-db.org/network/224308.BSU12140Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 16850406.
yjgB protein networkhttps://string-db.org/network/224308.BSU12150Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 1580552.
yjgC protein networkhttps://string-db.org/network/224308.BSU12160Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yjgD protein networkhttps://string-db.org/network/224308.BSU12170Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjhA protein networkhttps://string-db.org/network/224308.BSU12180Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
yjhB protein networkhttps://string-db.org/network/224308.BSU12190Putative ADP-ribose pyrophosphatase; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
yjiA protein networkhttps://string-db.org/network/224308.BSU12200Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yjiB protein networkhttps://string-db.org/network/224308.BSU12210Putative monooxygenase (cytochrome P450); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yjiC protein networkhttps://string-db.org/network/224308.BSU12220Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
yjzI protein networkhttps://string-db.org/network/224308.BSU12229Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjjA protein networkhttps://string-db.org/network/224308.BSU12230Putative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yjkA protein networkhttps://string-db.org/network/224308.BSU12240Putative ABC transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yjkB protein networkhttps://string-db.org/network/224308.BSU12250Putative phosphate ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: p [...]
yjlA protein networkhttps://string-db.org/network/224308.BSU12260Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yjlB protein networkhttps://string-db.org/network/224308.BSU12270Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10704478.
yjlC protein networkhttps://string-db.org/network/224308.BSU12280Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17015645.
ndh protein networkhttps://string-db.org/network/224308.BSU12290NADH dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the NADH dehydrogenase family.
uxaC protein networkhttps://string-db.org/network/224308.BSU12300Galacturonate isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
exuM protein networkhttps://string-db.org/network/224308.BSU12310Putative Na+:altronate/mannonate symporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t: transporter.
yjmC protein networkhttps://string-db.org/network/224308.BSU12320Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yjmD protein networkhttps://string-db.org/network/224308.BSU12330Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
uxuA protein networkhttps://string-db.org/network/224308.BSU12340D-mannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
uxuB protein networkhttps://string-db.org/network/224308.BSU12350Fructuronate reductase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
exuT protein networkhttps://string-db.org/network/224308.BSU12360Hexuronate transporter; Aldohexuronate transport system; Belongs to the major facilitator superfamily. Phthalate permease family.
exuR protein networkhttps://string-db.org/network/224308.BSU12370Transcriptional regulator (LacI family); Transcriptional repressor for the exu locus which is required for galacturonate utilization.
uxaB protein networkhttps://string-db.org/network/224308.BSU12380Tagaturonate reductase (altronate oxidoreductase); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the mannitol dehyd [...]
uxaA protein networkhttps://string-db.org/network/224308.BSU12390Altronate hydrolase; Catalyzes the dehydration of D-altronate; Belongs to the UxaA family.
yjnA protein networkhttps://string-db.org/network/224308.BSU12400Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yjoA protein networkhttps://string-db.org/network/224308.BSU12410Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yjoB protein networkhttps://string-db.org/network/224308.BSU12420ATPase possibly involved in protein degradation; Shows ATPase activity.
rapA protein networkhttps://string-db.org/network/224308.BSU12430Response regulator aspartate phosphatase; Prevents sporulation by dephosphorylating Spo0F. Belongs to the RAP family.
phrA protein networkhttps://string-db.org/network/224308.BSU12440Secreted inhibitor of the activity of phosphatase RapA; Inhibitor of the activity of phosphatase RapA.
yjpA protein networkhttps://string-db.org/network/224308.BSU12450Putative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the YciI family.
xlyB protein networkhttps://string-db.org/network/224308.BSU12460N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of [...]
yjqA protein networkhttps://string-db.org/network/224308.BSU12470Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Product type h: extrachromosomal origin.
yjqB protein networkhttps://string-db.org/network/224308.BSU12480Putative PBSX phage-related replication protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromo [...]
yjqC protein networkhttps://string-db.org/network/224308.BSU12490Putative PBSX phage manganese-containing catalase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachro [...]
xkdA protein networkhttps://string-db.org/network/224308.BSU12500PBSX phage protein, putative peptidase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; To B.subtilis YqaB.
xre protein networkhttps://string-db.org/network/224308.BSU12510Phage PBSX transcriptional regulator; Repressor of PBSX. Binds to four sites close to its own gene. Necessary for the maintenance of the lysogenic state.
yjzJ protein networkhttps://string-db.org/network/224308.BSU12519Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
xkdB protein networkhttps://string-db.org/network/224308.BSU12520Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqaL.
xkdC protein networkhttps://string-db.org/network/224308.BSU12530Conserved hypothetical protein in PBSX phage element; May function as a transcriptional antiterminator.
ykzK protein networkhttps://string-db.org/network/224308.BSU12539Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
xkdD protein networkhttps://string-db.org/network/224308.BSU12540Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
xtrA protein networkhttps://string-db.org/network/224308.BSU12550PBSX phage protein, homolog of YqaO of the skin element; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; To B.subtilis YqaO.
xpf protein networkhttps://string-db.org/network/224308.BSU12560Putative RNA polymerase PBSX sigma factor-like; Positive regulatory protein that acts at the late promoter PL.
xtmA protein networkhttps://string-db.org/network/224308.BSU12570PBSX defective prophage terminase (small subunit); Functions as a terminase; To B.subtilis YqaS and B.subtilis phage SPP1 terminase small subunit.
xtmB protein networkhttps://string-db.org/network/224308.BSU12580PBSX defective prophage terminase (large subunit); Functions as a terminase; To B.subtilis YqaT and phage SPP1 terminase large subunit.
xkdE protein networkhttps://string-db.org/network/224308.BSU12590Putative phage capsid protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure; Belongs [...]
xkdF protein networkhttps://string-db.org/network/224308.BSU12600Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbD.
xkdG protein networkhttps://string-db.org/network/224308.BSU12610Putative capsid protein of PBSX prophage; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structur [...]
ykzL protein networkhttps://string-db.org/network/224308.BSU12619Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
xkdH protein networkhttps://string-db.org/network/224308.BSU12620Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbH.
xkdI protein networkhttps://string-db.org/network/224308.BSU12630Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbI.
xkdJ protein networkhttps://string-db.org/network/224308.BSU12640Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbJ.
ykzM protein networkhttps://string-db.org/network/224308.BSU12649Conserved hypothetical protein from phage origin; Evidence 4: Homologs of previously reported genes of unknown function.
xkdK protein networkhttps://string-db.org/network/224308.BSU12650Conserved hypothetical protein in phage element PBSX; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the myoviridae tail sheath protein family.
xkdM protein networkhttps://string-db.org/network/224308.BSU12660Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbM.
xkdN protein networkhttps://string-db.org/network/224308.BSU12671Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbN.
xkzB protein networkhttps://string-db.org/network/224308.BSU12672Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
xkdO protein networkhttps://string-db.org/network/224308.BSU12680Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbO.
xkdP protein networkhttps://string-db.org/network/224308.BSU12690Putative PBSX prophage murein binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative fac [...]
xkdQ protein networkhttps://string-db.org/network/224308.BSU12700Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbQ.
xkdR protein networkhttps://string-db.org/network/224308.BSU12710Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbR.
xkdS protein networkhttps://string-db.org/network/224308.BSU12720Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbS.
xkdT protein networkhttps://string-db.org/network/224308.BSU12730Putative base plate assembly protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belo [...]
xkdU protein networkhttps://string-db.org/network/224308.BSU12740Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqcA.
xkzA protein networkhttps://string-db.org/network/224308.BSU12749Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
xkdV protein networkhttps://string-db.org/network/224308.BSU12750Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqcC.
xkdW protein networkhttps://string-db.org/network/224308.BSU12760Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqcC.
xkdX protein networkhttps://string-db.org/network/224308.BSU12770Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqcE.
xepA protein networkhttps://string-db.org/network/224308.BSU12780Lytic exoenzyme associated with defective prophage PBSX; Not known; does not seem to be involved in host cell lysis.
xhlA protein networkhttps://string-db.org/network/224308.BSU12790Defective prophage PBSX putative enzyme; Associated with cell lysis upon induction of PbsX; To B.licheniformis xpaF1 and xpaL1.
xhlB protein networkhttps://string-db.org/network/224308.BSU12800Bacteriophage PBSX holin; Involved in cell lysis upon induction of PbsX; Belongs to the SPP1 holin family.
xlyA protein networkhttps://string-db.org/network/224308.BSU12810Bacteriophage PBSX N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transform [...]
spoIISB protein networkhttps://string-db.org/network/224308.BSU12820Two-component apoptotic control system component B (antitoxin); Antitoxin component of a type II toxin-antitoxin (TA) system. Antitoxin that binds cognate toxin SpoIISA and neutralizes its toxic [...]
spoIISA protein networkhttps://string-db.org/network/224308.BSU12830Two-component apoptosis factor (toxin/antitoxin system); Toxic component of a type II toxin-antitoxin (TA) system. Its toxic activity is neutralized by cognate antitoxin SpoIISB. Expression in th [...]
pit protein networkhttps://string-db.org/network/224308.BSU12840Low-affinity inorganic phosphate transporter; Low-affinity inorganic phosphate transport; Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
ykaA protein networkhttps://string-db.org/network/224308.BSU12850Putative Pit accessory protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the UPF0111 fami [...]
ykbA protein networkhttps://string-db.org/network/224308.BSU12860Putative amino acid permease; Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids.
mhqA protein networkhttps://string-db.org/network/224308.BSU12870Putative hydroquinone-specific extradiol dioxygenase; Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds.
ykcB protein networkhttps://string-db.org/network/224308.BSU12880Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane compo [...]
ykcC protein networkhttps://string-db.org/network/224308.BSU12890Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
htrA protein networkhttps://string-db.org/network/224308.BSU12900Membrane bound serine protease Do, quality control protease (heat-shock protein); Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and fo [...]
proG protein networkhttps://string-db.org/network/224308.BSU12910Redundant pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
dppA protein networkhttps://string-db.org/network/224308.BSU12920D-alanyl-aminopeptidase; Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physio [...]
dppB protein networkhttps://string-db.org/network/224308.BSU12930Dipeptide ABC transporter (permease); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is ex [...]
dppC protein networkhttps://string-db.org/network/224308.BSU12940Dipeptide ABC transporter (permease); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is ex [...]
dppD protein networkhttps://string-db.org/network/224308.BSU12950Dipeptide ABC transporter (ATP-binding protein); Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system. Expressed [...]
dppE protein networkhttps://string-db.org/network/224308.BSU12960Dipeptide ABC transporter (dipeptide-binding lipoprotein); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affi [...]
ldcA protein networkhttps://string-db.org/network/224308.BSU12970Muropeptide L,D-carboxypeptidase; May be involved in the degradation of peptidoglycan by catalyzing the cleavage of the terminal D-alanine residue from cytoplasmic murein peptides; Belongs to the [...]
ykfB protein networkhttps://string-db.org/network/224308.BSU12980L-Ala-D/L-Glu epimerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also ab [...]
ykfC protein networkhttps://string-db.org/network/224308.BSU12990gamma-D-glutamyl-L-diaminoacid endopeptidase; Specifically hydrolyzes gamma-D-glutamyl-L-lysine bonds in murein peptides, releasing L-Ala-D-Glu.
ykfD protein networkhttps://string-db.org/network/224308.BSU13000Putative cell wall oligopeptide ABC transporter (ATP binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putat [...]
pgl protein networkhttps://string-db.org/network/224308.BSU130106-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.
ykgA protein networkhttps://string-db.org/network/224308.BSU13020Putative aminohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the DD [...]
ykhA protein networkhttps://string-db.org/network/224308.BSU13030Putative acyl-CoA hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to th [...]
hmp protein networkhttps://string-db.org/network/224308.BSU13040Flavohemoglobin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the [...]
ykzH protein networkhttps://string-db.org/network/224308.BSU13050Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ykjA protein networkhttps://string-db.org/network/224308.BSU13060Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ykkA protein networkhttps://string-db.org/network/224308.BSU13070Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ykkB protein networkhttps://string-db.org/network/224308.BSU13080Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
ykkC protein networkhttps://string-db.org/network/224308.BSU13090Efflux transporter; Probably involved in guanidinium transport. In vitro, confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials.
ykkD protein networkhttps://string-db.org/network/224308.BSU13100Efflux transporter; Probably involved in guanidinium transport. In vitro, confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials.
purU protein networkhttps://string-db.org/network/224308.BSU13110Formyltetrahydrofolate hydrolase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
proB protein networkhttps://string-db.org/network/224308.BSU13120Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
proA protein networkhttps://string-db.org/network/224308.BSU13130Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclizat [...]
ohrA protein networkhttps://string-db.org/network/224308.BSU13140Peroxiredoxin; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family.
ohrR protein networkhttps://string-db.org/network/224308.BSU13150Transcriptional regulator sensing organic peroxides; Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements.
ohrB protein networkhttps://string-db.org/network/224308.BSU13160Organic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family.
ykzN protein networkhttps://string-db.org/network/224308.BSU13169Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
guaD protein networkhttps://string-db.org/network/224308.BSU13170Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.
metE protein networkhttps://string-db.org/network/224308.BSU13180Cobalamin-independent methionine synthase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation.
isp protein networkhttps://string-db.org/network/224308.BSU13190Intracellular serine protease; Major intracellular protease produced by Bacillus subtilis.
rsbRB protein networkhttps://string-db.org/network/224308.BSU13200Component of the piezosome (stressosome); One of 4 functionally non-identical RsbR paralogs, it functions in the environmental signaling branch of the general stress response.
thiX protein networkhttps://string-db.org/network/224308.BSU13210Thiamine transporter, permease component; Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing [...]
thiW protein networkhttps://string-db.org/network/224308.BSU13220Thiamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-cont [...]
thiV protein networkhttps://string-db.org/network/224308.BSU13230Thiamine transporter, permease component; Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing [...]
thiU protein networkhttps://string-db.org/network/224308.BSU13240Thiamine binding protein; Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Binds [...]
ykoG protein networkhttps://string-db.org/network/224308.BSU13250Two-component response regulator [YkoH]; Probable member of the two-component regulatory system YkoH/YkoG.
ykoH protein networkhttps://string-db.org/network/224308.BSU13260Two-component sensor histidine kinase [YkoG]; Probable member of the two-component regulatory system YkoH/YkoG. Potentially phosphorylates YkoG.
ykoI protein networkhttps://string-db.org/network/224308.BSU13270Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ykoJ protein networkhttps://string-db.org/network/224308.BSU13280Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; phenotype.
ykzD protein networkhttps://string-db.org/network/224308.BSU13290Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
mgtE protein networkhttps://string-db.org/network/224308.BSU13300Magnesium transporter; Acts as a magnesium transporter.
tnrA protein networkhttps://string-db.org/network/224308.BSU13310Nitrogen sensing transcriptional regulator; Transcription regulator that actives the transcription of genes required for nitrogen assimilation such as nrgAB (ammonium transport), nasABCDEF (nitra [...]
ykzB protein networkhttps://string-db.org/network/224308.BSU13320Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 10671441.
ykoL protein networkhttps://string-db.org/network/224308.BSU13330Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 10671441.
ykoM protein networkhttps://string-db.org/network/224308.BSU13340Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
ykoN protein networkhttps://string-db.org/network/224308.BSU13350Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
ykoP protein networkhttps://string-db.org/network/224308.BSU13360Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ykoQ protein networkhttps://string-db.org/network/224308.BSU13370Putative metallophosphoesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ykoS protein networkhttps://string-db.org/network/224308.BSU13380Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ykoT protein networkhttps://string-db.org/network/224308.BSU13390Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
ykoU protein networkhttps://string-db.org/network/224308.BSU13400ATP-dependent DNA ligase subunit; With Ku forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity (Probable). Probably involved in DNA repair [...]
ykoV protein networkhttps://string-db.org/network/224308.BSU13410ATP-dependent DNA ligase subunit; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- over [...]
ykoW protein networkhttps://string-db.org/network/224308.BSU13420Putative sensor diguanylate cyclase; Probable signaling protein whose physiological role is not yet known.
ykoX protein networkhttps://string-db.org/network/224308.BSU13430Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ykoY protein networkhttps://string-db.org/network/224308.BSU13440Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
sigI protein networkhttps://string-db.org/network/224308.BSU13450RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved i [...]
rsgI protein networkhttps://string-db.org/network/224308.BSU13460sigmaI modulating factor; Anti-sigma factor for SigI. Negatively regulates SigI activity through direct interaction.
sspD protein networkhttps://string-db.org/network/224308.BSU13470Small acid-soluble spore protein (alpha/beta-type SASP); SASP are bound to spore DNA. They are double-stranded DNA- binding proteins that cause DNA to change to an a-like conformation. They prote [...]
htpK protein networkhttps://string-db.org/network/224308.BSU13480Regulator of quality control; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
htpX protein networkhttps://string-db.org/network/224308.BSU13490Membrane protease; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the peptidase M48B family.
ktrD protein networkhttps://string-db.org/network/224308.BSU13500K+-transporting ATPase; Integral membrane subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed [...]
ykzP protein networkhttps://string-db.org/network/224308.BSU13509Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ykzE protein networkhttps://string-db.org/network/224308.BSU13510Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ykrP protein networkhttps://string-db.org/network/224308.BSU13520Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
kinE protein networkhttps://string-db.org/network/224308.BSU13530Two-component sensor histidine kinase; Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F.
ogt protein networkhttps://string-db.org/network/224308.BSU13540O6-alkylguanine DNA alkyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nuc [...]
mtnA protein networkhttps://string-db.org/network/224308.BSU13550Methylthioribose-1-phosphate isomerase (methionine salvage pathway); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
mtnK protein networkhttps://string-db.org/network/224308.BSU13560Methylthioribose kinase (methionine salvage pathway); Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
mtnU protein networkhttps://string-db.org/network/224308.BSU13570Ketoglutaramate omega-amidase; May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway; Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
mtnE protein networkhttps://string-db.org/network/224308.BSU13580Methionine-glutamine aminotransferase; Catalyzes the formation of methionine from 2-keto-4- methylthiobutyrate (KMTB).
mtnW protein networkhttps://string-db.org/network/224308.BSU135902,3-diketo-5-methylthiopentyl-1-phosphate enolase (DK-MTP-1-P enolase); Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopent [...]
mtnX protein networkhttps://string-db.org/network/224308.BSU136002-hydroxy-3-keto-5-methylthiopentenyl-1- phosphatephosphatase (HK-MTPenyl-1-P phosphatase); Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P) yielding 1,2-dihyd [...]
mtnB protein networkhttps://string-db.org/network/224308.BSU13610Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase); Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1- [...]
mtnD protein networkhttps://string-db.org/network/224308.BSU13620Acireductone dioxygenase (Ni2+ or Fe2+-requiring); Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the me [...]
ykvA protein networkhttps://string-db.org/network/224308.BSU13630Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
spo0E protein networkhttps://string-db.org/network/224308.BSU13640Negative regulatory phosphatase acting on Spo0A-P (sporulation); Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively reg [...]
eag protein networkhttps://string-db.org/network/224308.BSU13650Putative small membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane componen [...]
kinD protein networkhttps://string-db.org/network/224308.BSU13660Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical g [...]
mhqR protein networkhttps://string-db.org/network/224308.BSU13670Transcriptional regulator (MarR family); Negatively regulates mhqA, mhqED, mhqNOP, and azoR2 which may contribute to the degradation of aromatic compounds.
motB protein networkhttps://string-db.org/network/224308.BSU13680Motility protein B; MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque-generatin [...]
motA protein networkhttps://string-db.org/network/224308.BSU13690Motility protein A; MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity).
clpE protein networkhttps://string-db.org/network/224308.BSU13700ATP-dependent Clp protease (class III stress gene); ATPase essential both for efficient CtsR-dependent gene derepression during heat stress and for rerepression. Together with ClpP, degrades the [...]
ykvI protein networkhttps://string-db.org/network/224308.BSU13710Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
queC protein networkhttps://string-db.org/network/224308.BSU13720Pre-queuosine 0 synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Uses ammonia as nitrogen donor.
queD protein networkhttps://string-db.org/network/224308.BSU137306-carboxy-5,6,7,8-tetrahydropterin synthase; Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. Belongs to the PT [...]
queE protein networkhttps://string-db.org/network/224308.BSU137407-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to [...]
queF protein networkhttps://string-db.org/network/224308.BSU13750NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1), a late step in the queuosine [...]
ykvN protein networkhttps://string-db.org/network/224308.BSU13760Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
ykvO protein networkhttps://string-db.org/network/224308.BSU13770Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydro [...]
ykvP protein networkhttps://string-db.org/network/224308.BSU13780Spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
ykzQ protein networkhttps://string-db.org/network/224308.BSU13789Putative peptidoglycan binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
ykvQ protein networkhttps://string-db.org/network/224308.BSU13790Putative sporulation-specific glycosylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the g [...]
ykzR protein networkhttps://string-db.org/network/224308.BSU13799Putative spore-specific glycosyl hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the [...]
ykvR protein networkhttps://string-db.org/network/224308.BSU13800Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ykvS protein networkhttps://string-db.org/network/224308.BSU13810Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ykzS protein networkhttps://string-db.org/network/224308.BSU13819Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ykvT protein networkhttps://string-db.org/network/224308.BSU13820Cell wall hydrolase related to spore cortex-lytic enzymes; Evidence 2b: Function of strongly homologous gene; enzyme.
ykvU protein networkhttps://string-db.org/network/224308.BSU13830Spore membrane protein involved in germination; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type m: membrane component.
stoA protein networkhttps://string-db.org/network/224308.BSU13840Thiol-disulfide isomerase; Thiol-disulfide oxidoreductase with a reductive function, involved in spore cortex synthesis. It could be involved either in breaking disulfide bonds in cortex componen [...]
zosA protein networkhttps://string-db.org/network/224308.BSU13850Zn transporter; Couples the hydrolysis of ATP with the transport of zinc into the cell. Plays an important role in protecting cells against oxidative stress. ZosA-mediated zinc transport is requi [...]
ykvY protein networkhttps://string-db.org/network/224308.BSU13860Putative Xaa-Pro dipeptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
ykvZ protein networkhttps://string-db.org/network/224308.BSU13870Putative transcriptional regulator (LacI family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
glcT protein networkhttps://string-db.org/network/224308.BSU13880Transcriptional antiterminator (BglG family); Mediates the positive regulation of the glucose PTS operon (ptsGHI) by functioning as an antiterminator factor of transcription via its interaction w [...]
ptsG protein networkhttps://string-db.org/network/224308.BSU13890Phosphotransferase system (PTS) glucose-specific enzyme IICBA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport syste [...]
ptsH protein networkhttps://string-db.org/network/224308.BSU13900Histidine-containing phosphocarrier protein of the phosphotransferase system (PTS) (HPr protein); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransfer [...]
ptsI protein networkhttps://string-db.org/network/224308.BSU13910Phosphotransferase system (PTS) enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-t [...]
splA protein networkhttps://string-db.org/network/224308.BSU13920TRAP-like transcriptional regulator; Regulator of the spore photoproduct lyase operon (splAB).
splB protein networkhttps://string-db.org/network/224308.BSU13930Spore photoproduct (thymine dimer) lyase; Involved in repair of UV radiation-induced DNA damage during spore germination. Can repair thymine dimer 5-thyminyl-5,6- dihydrothymine (known as spore p [...]
ykwB protein networkhttps://string-db.org/network/224308.BSU13940Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the [...]
mcpC protein networkhttps://string-db.org/network/224308.BSU13950Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside t [...]
ykwC protein networkhttps://string-db.org/network/224308.BSU13960Putative beta-hydroxyacid dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; B [...]
ykwD protein networkhttps://string-db.org/network/224308.BSU13970Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
pbpH protein networkhttps://string-db.org/network/224308.BSU13980Penicillin-binding enzyme for formation of rod-shaped peptidoglycan cell wall; Involved in the polymerization of peptidoglycan. Plays a redundant role with PBP2a in determining the rod shape of t [...]
kinA protein networkhttps://string-db.org/network/224308.BSU13990Sporulation-specific ATP-dependent protein histidine kinase; Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP.
dapX protein networkhttps://string-db.org/network/224308.BSU14000N-acetyl-L,L-diaminopimelate aminotransferase; Essential for murein biosynthesis. Probably catalyzes the conversion of L-2-acetamido-6-oxopimelate to N-acetyl-LL- 2,6-diaminopimelate (Probable); [...]
ykzT protein networkhttps://string-db.org/network/224308.BSU14009Hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
cheV protein networkhttps://string-db.org/network/224308.BSU14010Coupling protein and response regulator for CheA activity in response to attractants (chemotaxis); Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. [...]
ykyB protein networkhttps://string-db.org/network/224308.BSU14020Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ykuC protein networkhttps://string-db.org/network/224308.BSU14030Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ykuD protein networkhttps://string-db.org/network/224308.BSU14040Murein transglycosylase; Probable enzyme that may play an important role in cell wall biology; Belongs to the YkuD family.
ykuE protein networkhttps://string-db.org/network/224308.BSU14050Putative metallophosphoesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs t [...]
fadH protein networkhttps://string-db.org/network/224308.BSU14060Putative 2,4-dienoyl-CoA reductase; Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered [...]
ykuG protein networkhttps://string-db.org/network/224308.BSU14071Putative cell wall protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
ykzU protein networkhttps://string-db.org/network/224308.BSU14072Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ykuH protein networkhttps://string-db.org/network/224308.BSU14080Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ykuI protein networkhttps://string-db.org/network/224308.BSU14090Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ykuJ protein networkhttps://string-db.org/network/224308.BSU14100Putative RNA-specific modification enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
ykuK protein networkhttps://string-db.org/network/224308.BSU14110Putative RNAse; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
abbA protein networkhttps://string-db.org/network/224308.BSU14120Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
ykuL protein networkhttps://string-db.org/network/224308.BSU14130Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11985717.
ccpC protein networkhttps://string-db.org/network/224308.BSU14140Transcriptional repressor of citB and citZ; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; Belongs to the LysR transcriptional regulatory fami [...]
ykuN protein networkhttps://string-db.org/network/224308.BSU14150Short-chain flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
ykuO protein networkhttps://string-db.org/network/224308.BSU14160Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12354229.
ykuP protein networkhttps://string-db.org/network/224308.BSU14170Short-chain flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
dapH protein networkhttps://string-db.org/network/224308.BSU14180Tetrahydrodipicolinate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
dapL protein networkhttps://string-db.org/network/224308.BSU14190N-acetyl-diaminopimelate deacetylase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
ykuS protein networkhttps://string-db.org/network/224308.BSU14200Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0180 family.
ykuT protein networkhttps://string-db.org/network/224308.BSU14210Putative small-conductance mechanosensitive channel; May play a role in resistance to osmotic downshock. Belongs to the MscS (TC 1.A.23) family.
ykuU protein networkhttps://string-db.org/network/224308.BSU14220Putative 2-cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell prot [...]
ykuV protein networkhttps://string-db.org/network/224308.BSU14230Thiol-disulfide isomerase; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
rok protein networkhttps://string-db.org/network/224308.BSU14240Repressor of comK; Repressor of comK, the master regulator of competence development. Overexpression seems to be lethal. Represses at least 20 genes that specify membrane- localized and secreted [...]
yknT protein networkhttps://string-db.org/network/224308.BSU14250Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 15383836, 15743949.
mobA protein networkhttps://string-db.org/network/224308.BSU14260Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine din [...]
moeB protein networkhttps://string-db.org/network/224308.BSU14270Molybdopterin biosynthesis adenylyltransferase; Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein MoaD.
moeA protein networkhttps://string-db.org/network/224308.BSU14280Molybdene to molybdopterin ligation enzyme; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP; Belongs to the MoeA family.
mobB protein networkhttps://string-db.org/network/224308.BSU14290Molybdopterin-guanine dinucleotide biosynthesis protein B; GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor, and not necess [...]
moaE protein networkhttps://string-db.org/network/224308.BSU14300Molybdopterin synthase (large subunit); Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. [...]
moaD protein networkhttps://string-db.org/network/224308.BSU14310Molybdopterin synthase (small subunit); Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin; Belongs to the MoaD family.
yknU protein networkhttps://string-db.org/network/224308.BSU14320Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative tr [...]
yknV protein networkhttps://string-db.org/network/224308.BSU14330Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative tr [...]
yknW protein networkhttps://string-db.org/network/224308.BSU14340Putative permease; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein). Has a role in the assembly of t [...]
yknX protein networkhttps://string-db.org/network/224308.BSU14350Putative efflux permease; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein).
yknY protein networkhttps://string-db.org/network/224308.BSU14360Putative ABC transporter (ATP-binding protein); Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein).
yknZ protein networkhttps://string-db.org/network/224308.BSU14370Putative permease; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein).
fruR protein networkhttps://string-db.org/network/224308.BSU14380Transcriptional regulator (DeoR family); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type r: regulator.
fruK protein networkhttps://string-db.org/network/224308.BSU14390Fructose-1-phosphate kinase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
fruA protein networkhttps://string-db.org/network/224308.BSU14400Phosphotransferase system (PTS) fructose-specific enzyme IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport syst [...]
sipT protein networkhttps://string-db.org/network/224308.BSU14410Type I signal peptidase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the peptidase S26 family.
ykoA protein networkhttps://string-db.org/network/224308.BSU14420Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ykpA protein networkhttps://string-db.org/network/224308.BSU14430ABC efflux transporter (ATP-binding protein); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t: transporter; Belongs to the ABC transporte [...]
panE protein networkhttps://string-db.org/network/224308.BSU14440Ketopantoate reductase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the ketopantoate reductase family.
ampS protein networkhttps://string-db.org/network/224308.BSU14450Aminopeptidase; Metal-dependent exopeptidase; Belongs to the peptidase M29 family.
ykpC protein networkhttps://string-db.org/network/224308.BSU14460Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
mreBH protein networkhttps://string-db.org/network/224308.BSU14470Cell-shape determining protein; Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus c [...]
abh protein networkhttps://string-db.org/network/224308.BSU14480Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; To B.subtilis AbrB and SpoVT.
kinC protein networkhttps://string-db.org/network/224308.BSU14490Two-component sensor histidine kinase; Phosphorylates the sporulation-regulatory protein spo0A.
ykqA protein networkhttps://string-db.org/network/224308.BSU14500Conserved hypothetical protein; Putative gamma-glutamylcyclotransferase.
ktrC protein networkhttps://string-db.org/network/224308.BSU14510Potassium uptake protein; Catalytic subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and p [...]
adeC protein networkhttps://string-db.org/network/224308.BSU14520Adenine deaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase fami [...]
rnjA protein networkhttps://string-db.org/network/224308.BSU14530Ribonuclease J1; An RNase that has endonuclease and 5'-3' exonuclease activity, playing a role in both rRNA and mRNA stability and degradation. Endonuclease activity can cleave within 4 nucleotid [...]
rnpZA protein networkhttps://string-db.org/network/224308.BSU14540Omega 1 subunit of RNA polymerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the UPF0356 family.
ykrA protein networkhttps://string-db.org/network/224308.BSU14550Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
defB protein networkhttps://string-db.org/network/224308.BSU14560Formylmethionine deformylase A; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methi [...]
BSU14568 protein networkhttps://string-db.org/network/224308.BSU14568Putative antitoxin; Evidence 5: No homology to any previously reported sequences; Product type pr: putative regulator.
ykzV protein networkhttps://string-db.org/network/224308.BSU14569Putative type I toxin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type f: factor.
ykyA protein networkhttps://string-db.org/network/224308.BSU14570Putative chromosome partitioning protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
pdhA protein networkhttps://string-db.org/network/224308.BSU14580Pyruvate dehydrogenase (E1 alpha subunit); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic [...]
pdhB protein networkhttps://string-db.org/network/224308.BSU14590Pyruvate dehydrogenase (E1 beta subunit); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic c [...]
pdhC protein networkhttps://string-db.org/network/224308.BSU14600Pyruvate dehydrogenase (dihydrolipoamide acetyltransferase E2 subunit); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multip [...]
pdhD protein networkhttps://string-db.org/network/224308.BSU14610Dihydrolipoyl dehydrogenase; Catalyzes the oxidation of dihydrolipoamide to lipoamide; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
slp protein networkhttps://string-db.org/network/224308.BSU14620Small peptidoglycan-associated lipoprotein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
rgpA protein networkhttps://string-db.org/network/224308.BSU14629Regulator of GapA synthesis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
speA protein networkhttps://string-db.org/network/224308.BSU14630Arginine decarboxylase; Catalyzes the formation of agmatine from arginine.
yktA protein networkhttps://string-db.org/network/224308.BSU14640Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 19429628; Belongs to the UPF0223 family.
yktB protein networkhttps://string-db.org/network/224308.BSU14650Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0637 family.
ykzI protein networkhttps://string-db.org/network/224308.BSU14660Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
suhB protein networkhttps://string-db.org/network/224308.BSU14670Inositol monophosphatase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the inositol monophosphatase superfamily.
ykzC protein networkhttps://string-db.org/network/224308.BSU14680Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yktD protein networkhttps://string-db.org/network/224308.BSU14690Conserved hypothetical protein; May be involved in polyketide synthesis.
nprE protein networkhttps://string-db.org/network/224308.BSU14700Extracellular neutral metalloprotease; Extracellular zinc metalloprotease; Belongs to the peptidase M4 family.
ylaA protein networkhttps://string-db.org/network/224308.BSU14710Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 16501307.
ylaB protein networkhttps://string-db.org/network/224308.BSU14720Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 16501307.
ylaC protein networkhttps://string-db.org/network/224308.BSU14730RNA polymerase ECF-type sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor cont [...]
ylaD protein networkhttps://string-db.org/network/224308.BSU14740anti-YlaC sigma factor; Anti-sigma factor for YlaC; Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily.
ylaE protein networkhttps://string-db.org/network/224308.BSU14750Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
ylaF protein networkhttps://string-db.org/network/224308.BSU14760Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
bipA protein networkhttps://string-db.org/network/224308.BSU14770GTPase; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the [...]
ylaH protein networkhttps://string-db.org/network/224308.BSU14780Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ylaI protein networkhttps://string-db.org/network/224308.BSU14790Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ylaJ protein networkhttps://string-db.org/network/224308.BSU14800Putative lipoprotein; Probably contributes, directly or indirectly, to early events in germination.
ylaK protein networkhttps://string-db.org/network/224308.BSU14810Putative phosphate starvation inducible protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; In the C-t [...]
ylaL protein networkhttps://string-db.org/network/224308.BSU14820Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
glsB protein networkhttps://string-db.org/network/224308.BSU14830Glutaminase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme.
ylaN protein networkhttps://string-db.org/network/224308.BSU14840Conserved hypothetical protein; Essential for cell growth and for normal cell shape.
ftsW protein networkhttps://string-db.org/network/224308.BSU14850Cell-division protein; Peptidoglycan polymerase that is essential for cell division.
pycA protein networkhttps://string-db.org/network/224308.BSU14860Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate [...]
ctaA protein networkhttps://string-db.org/network/224308.BSU14870heme-A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group. Also involved in the sporulation.
ctaB protein networkhttps://string-db.org/network/224308.BSU14880Protoheme IX farnesyltransferase 2; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belon [...]
ctaC protein networkhttps://string-db.org/network/224308.BSU14890Cytochrome caa3 oxidase (subunit II); Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear [...]
ctaD protein networkhttps://string-db.org/network/224308.BSU14900Cytochrome caa3 oxidase (subunit I); Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the e [...]
ctaE protein networkhttps://string-db.org/network/224308.BSU14910Cytochrome caa3 oxidase (subunit III); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the cytochrome c oxidase subunit 3 family.
ctaF protein networkhttps://string-db.org/network/224308.BSU14920Cytochrome caa3 oxidase (subunit IV); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the cytochrome c oxidase bacterial subunit 4 fami [...]
ctaG protein networkhttps://string-db.org/network/224308.BSU14930Cytochrome aa(3) assembly factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
ylbA protein networkhttps://string-db.org/network/224308.BSU14940Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ylbB protein networkhttps://string-db.org/network/224308.BSU14950Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ylbC protein networkhttps://string-db.org/network/224308.BSU14960Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ylbD protein networkhttps://string-db.org/network/224308.BSU14970Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ylbE protein networkhttps://string-db.org/network/224308.BSU14980Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ylbF protein networkhttps://string-db.org/network/224308.BSU14990Putative regulatory protein; Regulates sporulation prior to stage II. Positively controls the competence regulator ComK at a post-transcriptional level. May modulate the translation, stability or [...]
ylbG protein networkhttps://string-db.org/network/224308.BSU15000Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
rsmD protein networkhttps://string-db.org/network/224308.BSU15010Putative ribosomal RNA small subunit methyltransferase D; May catalyze the S-adenosyl-L-methionine-dependent methylation of a specific base in rRNA.
coaD protein networkhttps://string-db.org/network/224308.BSU15020Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD [...]
ylbJ protein networkhttps://string-db.org/network/224308.BSU15030Putative factor required for spore cortex formation; Required for spore cortex formation.
ylbK protein networkhttps://string-db.org/network/224308.BSU15040Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the NTE fam [...]
ylbL protein networkhttps://string-db.org/network/224308.BSU15050Putative degradative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ylbM protein networkhttps://string-db.org/network/224308.BSU15060Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acet [...]
ylzH protein networkhttps://string-db.org/network/224308.BSU15069Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ylbN protein networkhttps://string-db.org/network/224308.BSU15070Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11700356.
rpmF protein networkhttps://string-db.org/network/224308.BSU15080Ribosomal protein L32; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.
gerR protein networkhttps://string-db.org/network/224308.BSU15090DNA-binding regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
ylbP protein networkhttps://string-db.org/network/224308.BSU15100Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
panE-2 protein networkhttps://string-db.org/network/224308.BSU151102-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
bshC protein networkhttps://string-db.org/network/224308.BSU15120Malate glucosamine cysteine ligase; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate B [...]
mraZ protein networkhttps://string-db.org/network/224308.BSU15130Putative protein involved in cell division or replication; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp: [...]
mraW protein networkhttps://string-db.org/network/224308.BSU15140S-adenosyl-dependent methyltransferase active on membrane-located substrates; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ftsL protein networkhttps://string-db.org/network/224308.BSU15150Cell-division protein; Essential cell division protein that may play a structural role. Probably involved in the regulation of the timing of cell division. Also required for sporulation.
pbpB protein networkhttps://string-db.org/network/224308.BSU15160Penicillin-binding protein 2B; Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. PBP-2B is required for vegetative cell division and sporulation septation. Bet [...]
spoVD protein networkhttps://string-db.org/network/224308.BSU15170Penicillin-binding protein; Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidogly [...]
murE protein networkhttps://string-db.org/network/224308.BSU15180UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) [...]
mraY protein networkhttps://string-db.org/network/224308.BSU15190phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY su [...]
murD protein networkhttps://string-db.org/network/224308.BSU15200UDP-N-acetylmuramoylalanyl-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF fa [...]
spoVE protein networkhttps://string-db.org/network/224308.BSU15210Factor for spore cortex peptidoglycan synthesis (stage V sporulation); May play an essential role not only during sporulation, but also during vegetative growth; Belongs to the SEDS family. SpoVE [...]
murG protein networkhttps://string-db.org/network/224308.BSU15220Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
murB protein networkhttps://string-db.org/network/224308.BSU15230UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
divIB protein networkhttps://string-db.org/network/224308.BSU15240Cell-division initiation protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex. Plays an essential role in division at high temperat [...]
ylxW protein networkhttps://string-db.org/network/224308.BSU15250Conserved hypothetical protein; May be involved in cell division and sporulation. Belongs to the UPF0749 family.
ylxX protein networkhttps://string-db.org/network/224308.BSU15260Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
sbp protein networkhttps://string-db.org/network/224308.BSU15270Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ftsA protein networkhttps://string-db.org/network/224308.BSU15280Cell-division protein essential fo Z-ring assembly; Cell division protein that is required for the assembly of the Z ring. May serve as a membrane anchor for the Z ring (By similarity). Binds and [...]
ftsZ protein networkhttps://string-db.org/network/224308.BSU15290Cell-division initiation protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls t [...]
bpr protein networkhttps://string-db.org/network/224308.BSU15300Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
spoIIGA protein networkhttps://string-db.org/network/224308.BSU15310Protease processing pro-sigma-E; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the [...]
sigE protein networkhttps://string-db.org/network/224308.BSU15320RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then release [...]
sigG protein networkhttps://string-db.org/network/224308.BSU15330RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. [...]
ylmA protein networkhttps://string-db.org/network/224308.BSU15340Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
thiQ protein networkhttps://string-db.org/network/224308.BSU15350N-formyl-4-amino-5-aminomethyl-2- methylpyrimidinedeformylase; Catalyzes the deformylation of the formylaminopyrimidine N- formyl-4-amino-5-aminomethyl-2-methylpyrimidine (FAMP) to give the corre [...]
ylmC protein networkhttps://string-db.org/network/224308.BSU15360Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12429060.
ylmD protein networkhttps://string-db.org/network/224308.BSU15370Conserved hypothetical protein; Multicopper oxidase with polyphenol oxidase activity.
ylmE protein networkhttps://string-db.org/network/224308.BSU15380Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
sepF protein networkhttps://string-db.org/network/224308.BSU15390Cell division machinery factor; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-li [...]
ylmG protein networkhttps://string-db.org/network/224308.BSU15400Factor involved in shape determination and osmotic tolerance; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.
ylmH protein networkhttps://string-db.org/network/224308.BSU15410Factor involved in shape determination, RNA-binding fold; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.
divIVA protein networkhttps://string-db.org/network/224308.BSU15420Cell-division initiation protein; May act as a pilot protein, directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization [...]
ileS protein networkhttps://string-db.org/network/224308.BSU15430isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
ylyA protein networkhttps://string-db.org/network/224308.BSU15440Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15496987.
lspA protein networkhttps://string-db.org/network/224308.BSU15450Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
rluD protein networkhttps://string-db.org/network/224308.BSU15460Pseudouridylate synthase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme.
pyrR protein networkhttps://string-db.org/network/224308.BSU15470Transcriptional attenuator and uracil phosphoribosyltransferase activity; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner [...]
pyrP protein networkhttps://string-db.org/network/224308.BSU15480Uracil permease; Transport of uracil in the cell; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily.
pyrB protein networkhttps://string-db.org/network/224308.BSU15490Aspartate carbamoyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
pyrC protein networkhttps://string-db.org/network/224308.BSU15500Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
pyrAA protein networkhttps://string-db.org/network/224308.BSU15510Pyrimidine-specific carbamoyl-phosphate synthetase (small subunit, glutaminase subunit); Evidence 2b: Function of strongly homologous gene; enzyme.
pyrAB protein networkhttps://string-db.org/network/224308.BSU15520Pyrimidine-specific carbamoyl-phosphate synthetase (large subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the CarB family.
pyrK protein networkhttps://string-db.org/network/224308.BSU15530Dihydroorotate dehydrogenase (electron transfer subunit); Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD subunit to the ultima [...]
pyrD protein networkhttps://string-db.org/network/224308.BSU15540Dihydroorotate dehydrogenase (catalytic subunit); Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
pyrF protein networkhttps://string-db.org/network/224308.BSU15550Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamil [...]
pyrE protein networkhttps://string-db.org/network/224308.BSU15560Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
cysH protein networkhttps://string-db.org/network/224308.BSU15570(phospho)adenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite.
cysP protein networkhttps://string-db.org/network/224308.BSU15580Sulfate permease; Involved in the import of sulfate.
sat protein networkhttps://string-db.org/network/224308.BSU15590Sulfate adenylyltransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
cysC protein networkhttps://string-db.org/network/224308.BSU15600Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate; Belongs to the APS kinase family.
sumT protein networkhttps://string-db.org/network/224308.BSU15610Uroporphyrinogen III and precorrin-1 C-methyltransferase; Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-2; their oxidative esterification [...]
sirB protein networkhttps://string-db.org/network/224308.BSU15620Sirohydrochlorin ferrochelatase; Chelates iron to the siroheme precursor; Belongs to the CbiX family. SirB subfamily.
sirC protein networkhttps://string-db.org/network/224308.BSU15630Precorrin-2 dehydrogenase; Catalyzes the dehydrogenation of precorrin-2 to form sirohydrochlorin which is used as a precursor in both siroheme biosynthesis and in the anaerobic branch of adenosyl [...]
yloA protein networkhttps://string-db.org/network/224308.BSU15640Putative persistent RNA/DNA binding protein; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal sub [...]
yloB protein networkhttps://string-db.org/network/224308.BSU15650P-type calcium transport ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
yloC protein networkhttps://string-db.org/network/224308.BSU15660Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0701 family.
ylzA protein networkhttps://string-db.org/network/224308.BSU15670Conserved hypothetical protein; Regulates the biosynthesis of the extracellular matrix and the biofilm formation. Activates the transcription of the matrix biosynthesis operons eps and tapA-sipW- [...]
gmk protein networkhttps://string-db.org/network/224308.BSU15680Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
rpoZ protein networkhttps://string-db.org/network/224308.BSU15690Omega subunit of RNA polymerase; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunit [...]
coaBC protein networkhttps://string-db.org/network/224308.BSU15700Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'- phosphopantothenate to form 4 [...]
priA protein networkhttps://string-db.org/network/224308.BSU15710Primosomal replication factor Y (primosomal protein N'); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It [...]
defA protein networkhttps://string-db.org/network/224308.BSU15720Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
fmt protein networkhttps://string-db.org/network/224308.BSU15730methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
rsmB protein networkhttps://string-db.org/network/224308.BSU15740RNA-binding Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
rlmN protein networkhttps://string-db.org/network/224308.BSU1575023S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
prpC protein networkhttps://string-db.org/network/224308.BSU15760Phosphorylated protein phosphatase; Protein phosphatase that dephosphorylates PrkC and EF-G (elongation factor G, fusA). prpC and prkC are cotranscribed, which suggests that they form a functiona [...]
prkC protein networkhttps://string-db.org/network/224308.BSU15770Protein kinase; Protein kinase that is responsible for triggering spore germination in response to muropeptides, signaling bacteria to exit dormancy. PrkC is thus a germination receptor that bind [...]
cpgA protein networkhttps://string-db.org/network/224308.BSU15780GTPase involved in ribosome and sacculus morphogenesis; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA fr [...]
rpe protein networkhttps://string-db.org/network/224308.BSU15790Ribulose-5-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
thiN protein networkhttps://string-db.org/network/224308.BSU15800Thiamine pyrophosphokinase; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate.
spoVM protein networkhttps://string-db.org/network/224308.BSU15810Factor required for normal spore cortex and coat synthesis (stage V sporulation); Coordinates cortex and coat assembly during sporulation. Associates with the spore coat protein SpoIVA and with t [...]
rpmB protein networkhttps://string-db.org/network/224308.BSU15820Ribosomal protein L28; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.
yloU protein networkhttps://string-db.org/network/224308.BSU15830Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16014871, 17114254; Belongs to the asp23 family.
yloV protein networkhttps://string-db.org/network/224308.BSU15840Putative dihydroxyacetone/glyceraldehyde kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
sdaAB protein networkhttps://string-db.org/network/224308.BSU15850L-serine dehydratase (beta chain); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase fam [...]
sdaAA protein networkhttps://string-db.org/network/224308.BSU15860L-serine dehydratase (alpha chain); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the iron-sulfur dependent L-serin [...]
recG protein networkhttps://string-db.org/network/224308.BSU15870Branch migrating ATP-dependent DNA helicase involved in DNA recombination and repair; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature produc [...]
fapR protein networkhttps://string-db.org/network/224308.BSU15880Transcription factor controlling fatty acid and phospholipid metabolism; Transcription factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and [...]
plsX protein networkhttps://string-db.org/network/224308.BSU15890phosphate:acyl-ACP acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl don [...]
fabD protein networkhttps://string-db.org/network/224308.BSU15900Malonyl CoA:acyl carrier protein transacylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the FabD family.
fabG protein networkhttps://string-db.org/network/224308.BSU15910Beta-ketoacyl-acyl carrier protein reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation [...]
acpA protein networkhttps://string-db.org/network/224308.BSU15920Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
rnc protein networkhttps://string-db.org/network/224308.BSU15930Ribonuclease III; Digests double-stranded RNA. Involved in the processing of ribosomal RNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes [...]
smc protein networkhttps://string-db.org/network/224308.BSU15940Chromosome condensation and segregation SMC ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family.
ftsY protein networkhttps://string-db.org/network/224308.BSU15950Signal recognition particle (docking protein); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the sig [...]
ylqB protein networkhttps://string-db.org/network/224308.BSU15960Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535.
ylxM protein networkhttps://string-db.org/network/224308.BSU15970Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory [...]
ffh protein networkhttps://string-db.org/network/224308.BSU15980Signal recognition particle-like (SRP) GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribo [...]
rpsP protein networkhttps://string-db.org/network/224308.BSU15990Ribosomal protein S16 (BS17); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
ylqC protein networkhttps://string-db.org/network/224308.BSU16000Putative RNA binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belongs to t [...]
ylqD protein networkhttps://string-db.org/network/224308.BSU16010Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
rimM protein networkhttps://string-db.org/network/224308.BSU1602016S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Ess [...]
trmD protein networkhttps://string-db.org/network/224308.BSU16030tRNA(m1G37)methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rplS protein networkhttps://string-db.org/network/224308.BSU16040Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; Belongs to the bact [...]
rbgA protein networkhttps://string-db.org/network/224308.BSU16050Ribosome biogenesis GTPase A; Essential protein that is required for a late step of 50S ribosomal subunit assembly. Has GTPase activity that is stimulated by interaction with the immature 50S rib [...]
rnhB protein networkhttps://string-db.org/network/224308.BSU16060Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
ylqG protein networkhttps://string-db.org/network/224308.BSU16070Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ylqH protein networkhttps://string-db.org/network/224308.BSU16080Putative flagellar biosynthesis protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
sucC protein networkhttps://string-db.org/network/224308.BSU16090succinyl-CoA synthetase (beta subunit); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus re [...]
sucD protein networkhttps://string-db.org/network/224308.BSU16100succinyl-CoA synthetase (alpha subunit); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus r [...]
dprA protein networkhttps://string-db.org/network/224308.BSU16110DNA processing Smf single strand binding protein; Protein that helps load RecA onto ssDNA during transformation. Binds cooperatively to circular ssDNA, is able to bridge different segments of DNA [...]
topA protein networkhttps://string-db.org/network/224308.BSU16120DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of [...]
trmFO protein networkhttps://string-db.org/network/224308.BSU16130tRNA:m(5)U-54 methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
codV protein networkhttps://string-db.org/network/224308.BSU16140Site-specific tyrosine recombinase for chromosome partitioning; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- [...]
clpQ protein networkhttps://string-db.org/network/224308.BSU16150Two-component ATP-dependent protease (N-terminal serine protease); Protease subunit of a proteasome-like degradation complex. Belongs to the peptidase T1B family. HslV subfamily.
clpY protein networkhttps://string-db.org/network/224308.BSU16160Two-component ATP-dependent protease (ATPase and chaperone); ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity; Belongs to the ClpX chaperone family. Hs [...]
codY protein networkhttps://string-db.org/network/224308.BSU16170Transcriptional regulator, GTP and BCAA-dependent; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to s [...]
flgB protein networkhttps://string-db.org/network/224308.BSU16180Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
flgC protein networkhttps://string-db.org/network/224308.BSU16190Flagellar component of cell-proximal portion of basal-body rod; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type s: structure; Belongs to th [...]
fliE protein networkhttps://string-db.org/network/224308.BSU16200Flagellar basal body protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type s: structure.
fliF protein networkhttps://string-db.org/network/224308.BSU16210Flagellar basal-body M-ring protein; The M ring may be actively involved in energy transduction.
fliG protein networkhttps://string-db.org/network/224308.BSU16220Flagellar motor switching and energizing component; One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemo [...]
fliH protein networkhttps://string-db.org/network/224308.BSU16230Flagellar export apparatus component; Needed for flagellar regrowth and assembly.
fliI protein networkhttps://string-db.org/network/224308.BSU16240Flagellar-specific ATPase; Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.
fliJ protein networkhttps://string-db.org/network/224308.BSU16250Flagellar synthesis chaperone; Flagellar protein that affects chemotactic events.
ylxF protein networkhttps://string-db.org/network/224308.BSU16260Putative kinesin-like protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure.
fliK protein networkhttps://string-db.org/network/224308.BSU16270Flagellar hook-length control protein; Controls the length of the flagellar hook.
flgD protein networkhttps://string-db.org/network/224308.BSU16280Flagellar hook assembly protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type pf: putative factor; Belongs to the FlgD family.
flgE protein networkhttps://string-db.org/network/224308.BSU16290Flagellar hook protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor; Belongs to the flagella basal body rod proteins family.
ylzI protein networkhttps://string-db.org/network/224308.BSU16299Putative flagellar protein; Required for swarming motility. Increases flagellar power, probably via the flagellar stator components MotA and MotB.
fliL protein networkhttps://string-db.org/network/224308.BSU16300Flagellar basal-body associated protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
fliM protein networkhttps://string-db.org/network/224308.BSU16310Flagellar motor switching and energizing component; One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemo [...]
fliY protein networkhttps://string-db.org/network/224308.BSU16320Flagellar motor switching and energizing phosphatase; Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P arou [...]
cheY protein networkhttps://string-db.org/network/224308.BSU16330Regulator of chemotaxis and motility; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Phosphorylated CheY interacts with the flagella switch compo [...]
fliZ protein networkhttps://string-db.org/network/224308.BSU16340Flagellar regulatory protein; May be a structural component of the flagellum that anchors the rod to the membrane.
fliP protein networkhttps://string-db.org/network/224308.BSU16350Component of the flagellar export machinery; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
fliQ protein networkhttps://string-db.org/network/224308.BSU16360Component of the flagellar export machinery; Role in flagellar biosynthesis; Belongs to the FliQ/MopD/SpaQ family.
fliR protein networkhttps://string-db.org/network/224308.BSU16370Component of the flagellar export machinery; Role in flagellar biosynthesis; Belongs to the FliR/MopE/SpaR family.
flhB protein networkhttps://string-db.org/network/224308.BSU16380Component of the flagellar export machinery; May be involved in the export of flagellum proteins; Belongs to the type III secretion exporter family.
flhA protein networkhttps://string-db.org/network/224308.BSU16390Component of the flagellar export machinery; Involved in the export of flagellum proteins.
flhF protein networkhttps://string-db.org/network/224308.BSU16400GTPase involved in the export of flagella; Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.
ylxH protein networkhttps://string-db.org/network/224308.BSU16410Essential component of the flagellar assembly machinery; Involved in the placement and assembly of flagella (By similarity). Activates the SRP-GTPase activity of FlhF.
cheB protein networkhttps://string-db.org/network/224308.BSU16420Methyl-accepting chemotaxis proteins (MCP)-glutamate methylesterase; Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduc [...]
cheA protein networkhttps://string-db.org/network/224308.BSU16430Chemotactic two-component sensor histidine kinase; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its [...]
cheW protein networkhttps://string-db.org/network/224308.BSU16440Modulation of CheA activity in response to attractants (chemotaxis); Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheV and CheW are involved in [...]
cheC protein networkhttps://string-db.org/network/224308.BSU16450CheY-P phosphatase CheC; Involved in restoring normal CheY-P levels following the addition of attractant by increasing the rate of CheY-P hydrolysis. Is only 6% as active as FliY, which indicates [...]
cheD protein networkhttps://string-db.org/network/224308.BSU16460Chemoreceptor glutamine deamidase CheD; Deamidates 'Gln-593' and 'Gln-594' of the chemoreceptor McpA. In addition, deamidates other chemoreceptors, including McpB and McpC. CheD-mediated MCP (met [...]
sigD protein networkhttps://string-db.org/network/224308.BSU16470RNA polymerase sigma-28 factor (sigma-D); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This alternative s [...]
ylxL protein networkhttps://string-db.org/network/224308.BSU16480Coupling factor for flagellin transcription and translation; Required for swarming motility and for maximal sigma-D activity.
rpsB protein networkhttps://string-db.org/network/224308.BSU16490Ribosomal protein S2; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; structure.
tsf protein networkhttps://string-db.org/network/224308.BSU16500Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
pyrH protein networkhttps://string-db.org/network/224308.BSU16510Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP, with ATP or dATP as the most efficient phosphate donors. Is also able to phosphorylate 5-fluoro-UMP and 6-aza-UMP.
frr protein networkhttps://string-db.org/network/224308.BSU16520Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
uppS protein networkhttps://string-db.org/network/224308.BSU16530Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
cdsA protein networkhttps://string-db.org/network/224308.BSU16540Phosphatidate cytidylyltransferase (CDP-diglyceride synthase); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.
dxr protein networkhttps://string-db.org/network/224308.BSU165501-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Be [...]
rseP protein networkhttps://string-db.org/network/224308.BSU16560Regulator of sigma-W protease RasP; Is responsible for site-2 cleavage of the RsiW anti-sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release [...]
proS protein networkhttps://string-db.org/network/224308.BSU16570prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
polC protein networkhttps://string-db.org/network/224308.BSU16580DNA polymerase III (alpha subunit); Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity; Belongs to the DNA polymerase type-C family. PolC subf [...]
rimP protein networkhttps://string-db.org/network/224308.BSU16590Ribosome maturation factor; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
nusA protein networkhttps://string-db.org/network/224308.BSU16600Transcription translation coupling factor involved in Rho-dependent transcription termination; Participates in both transcription termination and antitermination.
ylxR protein networkhttps://string-db.org/network/224308.BSU16610Putative RNA binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
rplGA protein networkhttps://string-db.org/network/224308.BSU16620Ribosomal protein L7Ae; RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA, but also in box C/D and box C'/D' sRNAs.
infB protein networkhttps://string-db.org/network/224308.BSU16630Initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribo [...]
ylxP protein networkhttps://string-db.org/network/224308.BSU16640Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
rbfA protein networkhttps://string-db.org/network/224308.BSU16650Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
truB protein networkhttps://string-db.org/network/224308.BSU16660tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
ribC protein networkhttps://string-db.org/network/224308.BSU16670Bifunctional riboflavin kinase FAD synthase; Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
rpsO protein networkhttps://string-db.org/network/224308.BSU16680Ribosomal protein S15 (BS18); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging s [...]
pnpA protein networkhttps://string-db.org/network/224308.BSU16690Polynucleotide phosphorylase (PNPase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. Necessary for co [...]
ylxY protein networkhttps://string-db.org/network/224308.BSU16700Putative sugar deacetylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the polysaccharide d [...]
mlpA protein networkhttps://string-db.org/network/224308.BSU16710Specific processing protease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
ymxH protein networkhttps://string-db.org/network/224308.BSU16720Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the YlmC/YmxH family.
spoVFA protein networkhttps://string-db.org/network/224308.BSU16730Spore dipicolinate synthase subunit A; Together with DpaB, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA), which constitutes up to 10% of the dry weight of the spore.
spoVFB protein networkhttps://string-db.org/network/224308.BSU16740Spore dipicolinate synthase subunit B; Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA), which constitutes up to 10% of the dry weight of the spore.
asd protein networkhttps://string-db.org/network/224308.BSU16750Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the as [...]
dapG protein networkhttps://string-db.org/network/224308.BSU16760Aspartokinase I (alpha and beta subunits); Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched bio [...]
dapA protein networkhttps://string-db.org/network/224308.BSU16770Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
rnjB protein networkhttps://string-db.org/network/224308.BSU16780Ribonuclease J2; Endonucleolytically cleaves the 5'-leader sequence of certain mRNAs. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficient [...]
tepA protein networkhttps://string-db.org/network/224308.BSU16790Protein export-enhancing factor; Required for efficient translocation of pre-proteins across the membrane; Belongs to the peptidase S14 family. TepA subfamily.
ylzJ protein networkhttps://string-db.org/network/224308.BSU16799Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
spoIIIE protein networkhttps://string-db.org/network/224308.BSU16800Spore DNA translocase; Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation, for the final [...]
ymfC protein networkhttps://string-db.org/network/224308.BSU16810Putative transcriptional regulator (GntR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
ymfD protein networkhttps://string-db.org/network/224308.BSU16825Bacillibactin exporter; Involved in secretion of bacillibactin.
ymfF protein networkhttps://string-db.org/network/224308.BSU16845Putative metalloprotease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the p [...]
ymfH protein networkhttps://string-db.org/network/224308.BSU16860Putative processing protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ymfI protein networkhttps://string-db.org/network/224308.BSU16870Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydro [...]
ymfJ protein networkhttps://string-db.org/network/224308.BSU16880Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ymfM protein networkhttps://string-db.org/network/224308.BSU16910Conserved hypothetical protein with ACT domain; Evidence 7: Gene remnant.
pgsA protein networkhttps://string-db.org/network/224308.BSU16920CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidylt [...]
cinA protein networkhttps://string-db.org/network/224308.BSU16930Competence-damage inducible regulator; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the CinA family.
recA protein networkhttps://string-db.org/network/224308.BSU16940Multifunctional SOS repair factor; Multifunctional protein involved in homologous recombination, DNA repair and competence. Can catalyze the hydrolysis of (d)ATP in the presence of single-strande [...]
pbpX protein networkhttps://string-db.org/network/224308.BSU16950Penicillin-binding endopeptidase X; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the beta-lactamase family.
rny protein networkhttps://string-db.org/network/224308.BSU16960Endoribonuclease Y; Endoribonuclease that initiates mRNA decay. Initiates the decay of all SAM-dependent riboswitches, such as yitJ riboswitch. Involved in processing of the gapA operon mRNA, it [...]
ymdB protein networkhttps://string-db.org/network/224308.BSU16970Putative hydrolase involved in biofilm formation; Plays a central, regulatory role in the late adaptive responses and affects the levels of many genes. May act via regulation of cAMP levels. Decr [...]
spoVS protein networkhttps://string-db.org/network/224308.BSU16980Stage V sporulation protein S; Induced early in sporulation under the control of sigma-H. Interferes with sporulation at an early stage. Seems to play a positive role in allowing cells to progres [...]
tdh protein networkhttps://string-db.org/network/224308.BSU16990Threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
kbl protein networkhttps://string-db.org/network/224308.BSU170002-amino-3-ketobutyrate CoA ligase (glycine acetyl transferase); Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON [...]
miaB protein networkhttps://string-db.org/network/224308.BSU17010Enzyme for ms(2)i(6)A formation for tRNA modification; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine [...]
ymcA protein networkhttps://string-db.org/network/224308.BSU17020Master regulator for biofilm formation; May work together with YlbF to regulate community development.
cotE protein networkhttps://string-db.org/network/224308.BSU17030Morphogenic spore protein; Morphogenic protein required for the assembly of the outer coat of the endospore. Is also a regulatory protein for the expression of cotA, cotB, cotC, cotH and other ge [...]
mutS protein networkhttps://string-db.org/network/224308.BSU17040DNA mismatch repair recognition factor; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPa [...]
mutL protein networkhttps://string-db.org/network/224308.BSU17050DNA mismatch repair factor; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', [...]
ymzD protein networkhttps://string-db.org/network/224308.BSU17060Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ymcC protein networkhttps://string-db.org/network/224308.BSU17070Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
pksA protein networkhttps://string-db.org/network/224308.BSU17080Putative transcriptional regulator; Transcriptional regulation of the polyketide synthase operon.
pksB protein networkhttps://string-db.org/network/224308.BSU17090Putative hydrolase; Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism; Belongs to the metallo-beta-l [...]
pksC protein networkhttps://string-db.org/network/224308.BSU17100malonyl-CoA-acyltransferase involved in polyketide synthesis; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metaboli [...]
pksD protein networkhttps://string-db.org/network/224308.BSU17110Enzyme involved in polyketide synthesis; Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
pksE protein networkhttps://string-db.org/network/224308.BSU17120Enzyme involved in polyketide synthesis; Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. Probably [...]
acpK protein networkhttps://string-db.org/network/224308.BSU17130Acyl-carrier protein; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
pksF protein networkhttps://string-db.org/network/224308.BSU17140Decarboxylase converting malonyl-S-AcpK to acetyl-S-AcpK for polyketide synthesis; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved [...]
pksG protein networkhttps://string-db.org/network/224308.BSU17150acetyl-S-AcpK beta-ketothioester polyketide intermediate transferase; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary [...]
pksH protein networkhttps://string-db.org/network/224308.BSU17160Dehydratase for polyketide biosynthesis; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. Probably catalyze [...]
pksI protein networkhttps://string-db.org/network/224308.BSU17170Decarboxylase involved in polyketide synthesis; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. May have a [...]
pksJ protein networkhttps://string-db.org/network/224308.BSU17180Polyketide synthase of type I; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
pksL protein networkhttps://string-db.org/network/224308.BSU17190Polyketide synthase of type I; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
pksM protein networkhttps://string-db.org/network/224308.BSU17200Polyketide synthase; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
pksN protein networkhttps://string-db.org/network/224308.BSU17210Polyketide synthase of type I; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
pksR protein networkhttps://string-db.org/network/224308.BSU17220Polyketide synthase; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
pksS protein networkhttps://string-db.org/network/224308.BSU17230Cytochrome P450 of bacillaene metabolism; Involved in the metabolism of the antibiotic polyketide bacillaene which is involved in secondary metabolism. The substrate is dihydrobacillaene.
ymzB protein networkhttps://string-db.org/network/224308.BSU17240Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ymaE protein networkhttps://string-db.org/network/224308.BSU17250Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
aprX protein networkhttps://string-db.org/network/224308.BSU17260Alkaline serine protease; Displays serine protease activity. Seems to have a broad substrate specificity.
ymaC protein networkhttps://string-db.org/network/224308.BSU17270Conserved hypothetical protein; Evidence 7: Gene remnant; Belongs to the UPF0714 family.
ymaD protein networkhttps://string-db.org/network/224308.BSU17280Putative peroxiredoxin-related protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the OsmC [...]
ebrB protein networkhttps://string-db.org/network/224308.BSU17290Small multidrug efflux transporter; Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide, acriflavine, pyronine Y and safranin O. The efflux is [...]
ebrA protein networkhttps://string-db.org/network/224308.BSU17300Small multidrug resistance efflux transporter; Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide, acriflavine, pyronine Y and safranin O. Th [...]
ymaG protein networkhttps://string-db.org/network/224308.BSU17310Inner spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
ymaF protein networkhttps://string-db.org/network/224308.BSU17320Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
miaA protein networkhttps://string-db.org/network/224308.BSU17330tRNA isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formati [...]
hfq protein networkhttps://string-db.org/network/224308.BSU17340Hfq RNA chaperone; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in [...]
ymzC protein networkhttps://string-db.org/network/224308.BSU17350Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ymzA protein networkhttps://string-db.org/network/224308.BSU17360Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
nrdI protein networkhttps://string-db.org/network/224308.BSU17370Co-factor of ribonucleotide diphosphate reductase; Probably involved in ribonucleotide reductase function.
nrdE protein networkhttps://string-db.org/network/224308.BSU17380Ribonucleoside-diphosphate reductase (major subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotide [...]
nrdF protein networkhttps://string-db.org/network/224308.BSU17390Ribonucleoside-diphosphate reductase (minor subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotide [...]
ymaB protein networkhttps://string-db.org/network/224308.BSU17400Putative enzyme involved in deoxyribonucleotide synthesis; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
cwlC protein networkhttps://string-db.org/network/224308.BSU17410N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of [...]
spoVK protein networkhttps://string-db.org/network/224308.BSU17420Mother cell sporulation ATPase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
hflX protein networkhttps://string-db.org/network/224308.BSU17430Ribosome associating GTPase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
ynbB protein networkhttps://string-db.org/network/224308.BSU17440Putative C-S lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
glnR protein networkhttps://string-db.org/network/224308.BSU17450Transcriptional regulator (nitrogen metabolism); Transcription repressor that represses many genes including ureABC and tnrA, during nitrogen excess. On the contrary of the MerR members, which re [...]
glnA protein networkhttps://string-db.org/network/224308.BSU17460Glutamine synthetase; Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the re [...]
ynxB protein networkhttps://string-db.org/network/224308.BSU17470Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
ynzF protein networkhttps://string-db.org/network/224308.BSU17480Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
ynzG protein networkhttps://string-db.org/network/224308.BSU17490Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; Belongs to [...]
ynaB protein networkhttps://string-db.org/network/224308.BSU17500Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
ynaC protein networkhttps://string-db.org/network/224308.BSU17510Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ynaD protein networkhttps://string-db.org/network/224308.BSU17520Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
ynaE protein networkhttps://string-db.org/network/224308.BSU17530Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ynaF protein networkhttps://string-db.org/network/224308.BSU17540Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ynaG protein networkhttps://string-db.org/network/224308.BSU17550Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ynzI protein networkhttps://string-db.org/network/224308.BSU17559Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ynaI protein networkhttps://string-db.org/network/224308.BSU17560Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To L.lactis TrpF C-terminal region.
xynP protein networkhttps://string-db.org/network/224308.BSU17570Putative H+-xyloside symporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
xynB protein networkhttps://string-db.org/network/224308.BSU17580Xylan beta-1,4-xylosidase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme; Belongs to the glycosyl hydrolase 43 family.
xylR protein networkhttps://string-db.org/network/224308.BSU17590Transcriptional regulator; Transcriptional repressor of xylose-utilizing enzymes.
xylA protein networkhttps://string-db.org/network/224308.BSU17600Xylose isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the xylose isomerase family.
xylB protein networkhttps://string-db.org/network/224308.BSU17610Xylulose kinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate; Belongs to the FGGY kinase family.
yncB protein networkhttps://string-db.org/network/224308.BSU17620DNA nuclease, lipoprotein; Shows DNase activity on double strand DNA. Belongs to the thermonuclease family.
yncC protein networkhttps://string-db.org/network/224308.BSU17630Putative sugar transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
alrB protein networkhttps://string-db.org/network/224308.BSU17640Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
yncE protein networkhttps://string-db.org/network/224308.BSU17650Putative prophage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
yncF protein networkhttps://string-db.org/network/224308.BSU17660Deoxyuridine 5'-triphosphate pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellul [...]
cotU protein networkhttps://string-db.org/network/224308.BSU17670Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
thyA protein networkhttps://string-db.org/network/224308.BSU17680Hypothetical protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...]
yncM protein networkhttps://string-db.org/network/224308.BSU17690Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ynzK protein networkhttps://string-db.org/network/224308.BSU17699Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
cotC protein networkhttps://string-db.org/network/224308.BSU17700Spore coat protein (outer); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
tatAC protein networkhttps://string-db.org/network/224308.BSU17710Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- argi [...]
yndA protein networkhttps://string-db.org/network/224308.BSU17720Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yndB protein networkhttps://string-db.org/network/224308.BSU17730Putative stress-related ATPase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the AHA1 family.
ynzB protein networkhttps://string-db.org/network/224308.BSU17740Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yndD protein networkhttps://string-db.org/network/224308.BSU17750Putative spore germination protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
yndE protein networkhttps://string-db.org/network/224308.BSU17760Putative spore germination integral inner membrane protein; Involved in the germinative response to L-alanine. Could be an amino acid transporter (By similarity); Belongs to the amino acid-polyam [...]
yndF protein networkhttps://string-db.org/network/224308.BSU17770Putative spore germination lipoprotein; May be involved in spore germination. Belongs to the GerABKC lipoprotein family.
yndG protein networkhttps://string-db.org/network/224308.BSU17780Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yndH protein networkhttps://string-db.org/network/224308.BSU17790Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yndJ protein networkhttps://string-db.org/network/224308.BSU17800Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yndK protein networkhttps://string-db.org/network/224308.BSU17810Putative phage/plasmid replication protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal [...]
yndL protein networkhttps://string-db.org/network/224308.BSU17820Putative phage-related replication protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal [...]
yndM protein networkhttps://string-db.org/network/224308.BSU17830Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
fosB protein networkhttps://string-db.org/network/224308.BSU17840Metallothiol transferase; Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological th [...]
lexA protein networkhttps://string-db.org/network/224308.BSU17850Transcriptional repressor of the SOS regulon; Represses dinA, dinB, dinC, recA genes and itself by binding to the 14 bp palindromic sequence 5'-CGAACNNNNGTTCG-3'; some genes have a tandem consens [...]
yneA protein networkhttps://string-db.org/network/224308.BSU17860Cell division inhibitor; Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing rec [...]
yneB protein networkhttps://string-db.org/network/224308.BSU17870Putative cell division protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp: cell process.
ynzC protein networkhttps://string-db.org/network/224308.BSU17880Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12581363, 16267290, 18431750, 19306341; Belongs to the UPF0291 family.
tkt protein networkhttps://string-db.org/network/224308.BSU17890Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
pcfA protein networkhttps://string-db.org/network/224308.BSU17900Factor controlling DNA replication; Inhibits DNA replication in growing cells, thus reducing chromosome copy number and playing a significant role during the onset of sporulation.
yneF protein networkhttps://string-db.org/network/224308.BSU17910Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ynzD protein networkhttps://string-db.org/network/224308.BSU17920Spo0A-P phosphatase; Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in [...]
ccdA protein networkhttps://string-db.org/network/224308.BSU17930Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient [...]
yneI protein networkhttps://string-db.org/network/224308.BSU17940Putative response regulator (CheY homolog); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
yneJ protein networkhttps://string-db.org/network/224308.BSU17950Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yneK protein networkhttps://string-db.org/network/224308.BSU17960Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
cotM protein networkhttps://string-db.org/network/224308.BSU17970Spore coat protein (outer); Involved in spore outer coat assembly. May be part of a cross-linked insoluble skeleton that surrounds the spore, serves as a matrix for the assembly of additional out [...]
sspP protein networkhttps://string-db.org/network/224308.BSU17980Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the SspP family.
sspO protein networkhttps://string-db.org/network/224308.BSU17990Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the SspO family.
citB protein networkhttps://string-db.org/network/224308.BSU18000Aconitate hydratase (aconitase); Involved in both the tricarboxylic acid (TCA) and methylcitric acid cycles. Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Als [...]
yneN protein networkhttps://string-db.org/network/224308.BSU18010Putative membrane-bound proteins with a thioredoxin-like domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative en [...]
ynzL protein networkhttps://string-db.org/network/224308.BSU18019Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
sspN protein networkhttps://string-db.org/network/224308.BSU18020Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the SspN family.
tlp protein networkhttps://string-db.org/network/224308.BSU18030Small acid-soluble spore protein (thioredoxin-like protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the Tlp family.
yneP protein networkhttps://string-db.org/network/224308.BSU18040acyl-CoA thioesterase; Has acyl-CoA thioesterase activity.
yneQ protein networkhttps://string-db.org/network/224308.BSU18050Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yneR protein networkhttps://string-db.org/network/224308.BSU18060Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the HesB/IscA family.
plsY protein networkhttps://string-db.org/network/224308.BSU18070Acylphosphate:glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). Thi [...]
yneT protein networkhttps://string-db.org/network/224308.BSU18080Putative CoA-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
parE protein networkhttps://string-db.org/network/224308.BSU18090Subunit B of DNA topoisomerase IV; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circ [...]
parC protein networkhttps://string-db.org/network/224308.BSU18100Subunit A of DNA topoisomerase IV; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circ [...]
ynfC protein networkhttps://string-db.org/network/224308.BSU18110Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
alsT protein networkhttps://string-db.org/network/224308.BSU18120Amino acid carrier protein; Evidence 2b: Function of strongly homologous gene; Product type t: transporter; Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
eglS protein networkhttps://string-db.org/network/224308.BSU18130Endo-1,4-beta-glucanase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
ynfE protein networkhttps://string-db.org/network/224308.BSU18140Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
xynC protein networkhttps://string-db.org/network/224308.BSU18150Endo-xylanase; Catalyzes the depolymerization of methylglucuronoxylan (MeGAXn) from different sources. It cleaves the beta-1,4-xylosidic bond penultimate to that linking carbon one of the xylose [...]
xynD protein networkhttps://string-db.org/network/224308.BSU18160Arabinoxylan arabinofuranohydrolase; Cleaves arabinose units from O-2- or O-3-monosubstituted xylose residues, thereby assisting in arabinoxylan (AX) and short-chain arabinoxylo-oligosaccharide ( [...]
yngA protein networkhttps://string-db.org/network/224308.BSU18170Putative conserved membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane comp [...]
yngB protein networkhttps://string-db.org/network/224308.BSU18180Putative UTP-glucose-1-phosphate uridylyltransferase; Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diac [...]
yngC protein networkhttps://string-db.org/network/224308.BSU18190Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
nrnB protein networkhttps://string-db.org/network/224308.BSU18200Oligoribonuclease (nanoRNase); Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 [...]
yngE protein networkhttps://string-db.org/network/224308.BSU18210Putative methylcrotonoyl-CoA carboxylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the Ac [...]
yngF protein networkhttps://string-db.org/network/224308.BSU18220Putative Methylglutaconyl-CoA hydratase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the eno [...]
yngG protein networkhttps://string-db.org/network/224308.BSU18230Putative hydroxymethylglutaryl-CoA lyase; Involved in the catabolism of branched amino acids such as leucine; Belongs to the HMG-CoA lyase family.
yngHB protein networkhttps://string-db.org/network/224308.BSU18239acyl-CoA carboxylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type c: carrier.
yngHA protein networkhttps://string-db.org/network/224308.BSU18240Biotin carboxylase/methylcrotonoyl-CoA carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the [...]
yngI protein networkhttps://string-db.org/network/224308.BSU18250Putative acetoacetyl-CoA synthetase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e: enzyme; Belongs to the [...]
yngJ protein networkhttps://string-db.org/network/224308.BSU18260acyl-CoA dehydrogenase, short-chain specific; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the acyl-CoA dehydrogen [...]
ynzE protein networkhttps://string-db.org/network/224308.BSU18270Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yngK protein networkhttps://string-db.org/network/224308.BSU18280Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.
yngL protein networkhttps://string-db.org/network/224308.BSU18290Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ppsE protein networkhttps://string-db.org/network/224308.BSU18300Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acid Ile as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The act [...]
ppsD protein networkhttps://string-db.org/network/224308.BSU18310Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Pro, Gln and Tyr as part of the biosynthesis of the lipopeptide antibiotic plipas [...]
ppsC protein networkhttps://string-db.org/network/224308.BSU18320Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Glu and Ala/Val as part of the biosynthesis of the lipopeptide antibiotic plipast [...]
ppsB protein networkhttps://string-db.org/network/224308.BSU18330Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Tyr and Thr as part of the biosynthesis of the lipopeptide antibiotic plipastatin [...]
ppsA protein networkhttps://string-db.org/network/224308.BSU18340Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Glu and Orn as part of the biosynthesis of the lipopeptide antibiotic lipastatin. [...]
dacC protein networkhttps://string-db.org/network/224308.BSU18350D-alanyl-D-alanine carboxypeptidase; Catalyzes DD-carboxypeptidase and transpeptidation reactions.
galM protein networkhttps://string-db.org/network/224308.BSU18360Aldose 1-epimerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the aldose epimerase family.
yoeA protein networkhttps://string-db.org/network/224308.BSU18370Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
iseA protein networkhttps://string-db.org/network/224308.BSU18380Inhibitor of cell-separation enzymes; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
yoeC protein networkhttps://string-db.org/network/224308.BSU18390Putative bacteriophage integrase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs [...]
yoeD protein networkhttps://string-db.org/network/224308.BSU18400Putative excisionase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
ggt protein networkhttps://string-db.org/network/224308.BSU18410Membrane bound gamma-glutamyltranspeptidase; Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The meta [...]
ftsR protein networkhttps://string-db.org/network/224308.BSU18420Transcriptional regulator (LysR family); Regulates expression of the cell division protein ftsW, and is essential for cell viability during stationary phase.
yogA protein networkhttps://string-db.org/network/224308.BSU18430Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
gltB protein networkhttps://string-db.org/network/224308.BSU18440Glutamate synthase (small subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
gltA protein networkhttps://string-db.org/network/224308.BSU18450Glutamate synthase (large subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glutamate synthase family.
gltC protein networkhttps://string-db.org/network/224308.BSU18460Transcriptional regulator (LysR family); Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression.
proJ protein networkhttps://string-db.org/network/224308.BSU18470Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
proH protein networkhttps://string-db.org/network/224308.BSU18480Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
rtp protein networkhttps://string-db.org/network/224308.BSU18490Replication terminator protein; Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the te [...]
yoxD protein networkhttps://string-db.org/network/224308.BSU18500Putative oxido-reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the s [...]
yoxC protein networkhttps://string-db.org/network/224308.BSU18510Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yoxB protein networkhttps://string-db.org/network/224308.BSU18520Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yoaA protein networkhttps://string-db.org/network/224308.BSU18530Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the acetyltransfer [...]
yoaB protein networkhttps://string-db.org/network/224308.BSU18540Negatively charged metabolite transporter; Evidence 2b: Function of strongly homologous gene; Product type t: transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A. [...]
yoaC protein networkhttps://string-db.org/network/224308.BSU18550Hydroxylated metabolite kinase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme.
yoaD protein networkhttps://string-db.org/network/224308.BSU18560Putative 2-hydroxyacid dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yoaE protein networkhttps://string-db.org/network/224308.BSU18570Molybdopterin cofactor oxido-reductase; Evidence 2b: Function of strongly homologous gene; enzyme.
yoaF protein networkhttps://string-db.org/network/224308.BSU18580Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoaG protein networkhttps://string-db.org/network/224308.BSU18590Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
BSU18596 protein networkhttps://string-db.org/network/224308.BSU18596Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yozQ protein networkhttps://string-db.org/network/224308.BSU18600Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yoaH protein networkhttps://string-db.org/network/224308.BSU18610Putative methyl-accepting chemotaxis protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
yoaI protein networkhttps://string-db.org/network/224308.BSU18620Putative 4-hydroxyphenylacetate-3-hydroxylase; Catalyzes the hydroxylation of 4-hydroxyphenylacetic acid (4HPA), leading to the production of 3,4-dihydroxyphenylacetic acid (DHPA).
exlX protein networkhttps://string-db.org/network/224308.BSU18630Extracellular endoglucanase precursor (expansin); May promote colonization of plant roots. May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulo [...]
yoaK protein networkhttps://string-db.org/network/224308.BSU18640Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
pelB protein networkhttps://string-db.org/network/224308.BSU18650Pectin lyase; Catalyzes the depolymerization of pectins of methyl esterification degree from 13 to 75%, with an endo mode of action. Cannot degrade polygalacturonate (By similarity).
yoaM protein networkhttps://string-db.org/network/224308.BSU18660Conserved hypothetical protein; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Recognizes and binds ab [...]
yozS protein networkhttps://string-db.org/network/224308.BSU18669Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
yoaN protein networkhttps://string-db.org/network/224308.BSU18670Oxalate decarboxylase; Converts oxalate to formate and CO(2); To B.subtilis OxdC.
yoaO protein networkhttps://string-db.org/network/224308.BSU18680Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yoaP protein networkhttps://string-db.org/network/224308.BSU18690Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the acetyltransferase family.
yozT protein networkhttps://string-db.org/network/224308.BSU18709Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yozF protein networkhttps://string-db.org/network/224308.BSU18710Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
yoaR protein networkhttps://string-db.org/network/224308.BSU18720Putative factor for cell wall maintenance or synthesis; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
yoaS protein networkhttps://string-db.org/network/224308.BSU18730Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 16850406.
yozG protein networkhttps://string-db.org/network/224308.BSU18740Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
yoaT protein networkhttps://string-db.org/network/224308.BSU18750Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yoaU protein networkhttps://string-db.org/network/224308.BSU18760Putative transcriptional regulator (LysR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
cyeA protein networkhttps://string-db.org/network/224308.BSU18770Cysteine and O-acetyl serine efflux permease; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; transporter.
yoaW protein networkhttps://string-db.org/network/224308.BSU18780Biofilm forming exported protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type ph: phenotype.
yoaZ protein networkhttps://string-db.org/network/224308.BSU18790Putative factor of the oxidative stress response; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs t [...]
penP protein networkhttps://string-db.org/network/224308.BSU18800Beta-lactamase precursor; This protein is a beta-lactamase with a substrate specificity for penicillins.
yobA protein networkhttps://string-db.org/network/224308.BSU18810Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yobB protein networkhttps://string-db.org/network/224308.BSU18820Putative phage protein; Evidence 7: Gene remnant; extrachromosomal origin.
pps protein networkhttps://string-db.org/network/224308.BSU18830Putative PEP-dependent enzyme; Might catalyze the phosphorylation of pyruvate to phosphoenolpyruvate.
xynA protein networkhttps://string-db.org/network/224308.BSU18840Endo-1,4-beta-xylanase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 11 (cellulase G) family.
yozV protein networkhttps://string-db.org/network/224308.BSU18849Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
yobD protein networkhttps://string-db.org/network/224308.BSU18850Transcriptional regulator (phage-related, Xre family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin.
yozH protein networkhttps://string-db.org/network/224308.BSU18860Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yozI protein networkhttps://string-db.org/network/224308.BSU18870Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yobE protein networkhttps://string-db.org/network/224308.BSU18880Putative phage protein; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Recognizes and binds abasic sit [...]
yobF protein networkhttps://string-db.org/network/224308.BSU18890Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yozW protein networkhttps://string-db.org/network/224308.BSU18898Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yozX protein networkhttps://string-db.org/network/224308.BSU18899Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
yozJ protein networkhttps://string-db.org/network/224308.BSU18900Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yozY protein networkhttps://string-db.org/network/224308.BSU18908Putative transcriptional regulator from bacteriophage; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extra [...]
rapK protein networkhttps://string-db.org/network/224308.BSU18910Putative phage holin (fragment); Evidence 7: Gene remnant; extrachromosomal origin; Belongs to the RAP family.
phrK protein networkhttps://string-db.org/network/224308.BSU18920Secreted regulator of the activity of phosphatase RapK; Inhibitor of the activity of phosphatase RapK.
yobH protein networkhttps://string-db.org/network/224308.BSU18930Putative DNA repair protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to th [...]
yozK protein networkhttps://string-db.org/network/224308.BSU18940Putative DNA repair protein fragment; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.
yozL protein networkhttps://string-db.org/network/224308.BSU18950Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951.
yozM protein networkhttps://string-db.org/network/224308.BSU18960Putative bacteriophage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
yobI protein networkhttps://string-db.org/network/224308.BSU18970Putative NTPase with transmembrane helices; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yobJ protein networkhttps://string-db.org/network/224308.BSU18980Small regulatory RNA; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type n: RNA.
rttM protein networkhttps://string-db.org/network/224308.BSU18990Antitoxin inhibiting Rnase RttL; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the RNase activity of cognate toxin YobL, as well as its ability to inhibit growth upon [...]
rttL protein networkhttps://string-db.org/network/224308.BSU19000Phage toxin ribonuclease; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 449-600) has RNase activity, and inhibits growth upon expression in E.coli. In vitro R [...]
yobM protein networkhttps://string-db.org/network/224308.BSU19010Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
yobN protein networkhttps://string-db.org/network/224308.BSU19020Putative amine oxidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the fla [...]
yobO protein networkhttps://string-db.org/network/224308.BSU19030Putative phage-related pre-neck appendage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachro [...]
csaA protein networkhttps://string-db.org/network/224308.BSU19040Molecular chaperone; Can suppress growth and secretion defects in E.coli secA and secB mutants. Probably a molecular chaperone for exported proteins or may act by stabilizing the SecA protein.
yobQ protein networkhttps://string-db.org/network/224308.BSU19050Putative transcriptional regulator (AraC/XylS family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
yobR protein networkhttps://string-db.org/network/224308.BSU19060Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the acetyltransferas [...]
yobS protein networkhttps://string-db.org/network/224308.BSU19070Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
yobT protein networkhttps://string-db.org/network/224308.BSU19080Putative metal-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yobU protein networkhttps://string-db.org/network/224308.BSU19090Putative effector of transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative fa [...]
yobV protein networkhttps://string-db.org/network/224308.BSU19100Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
yobW protein networkhttps://string-db.org/network/224308.BSU19110Mother cell-specific membrane sporulation protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
czrA protein networkhttps://string-db.org/network/224308.BSU19120Transcriptional regulator (multiple metal-sensing ArsR-SmtB transcriptional repressors family); Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA o [...]
yocA protein networkhttps://string-db.org/network/224308.BSU19130Putative transposon-related lytic enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal o [...]
yozB protein networkhttps://string-db.org/network/224308.BSU19140Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yocB protein networkhttps://string-db.org/network/224308.BSU19150Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yocC protein networkhttps://string-db.org/network/224308.BSU19160Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yocD protein networkhttps://string-db.org/network/224308.BSU19170Putative carboxypeptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the [...]
des protein networkhttps://string-db.org/network/224308.BSU19180Fatty acid desaturase; Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific f [...]
desK protein networkhttps://string-db.org/network/224308.BSU19190Two-component sensor histidine kinase [DesR]; Member of the two-component regulatory system DesR/DesK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. [...]
desR protein networkhttps://string-db.org/network/224308.BSU19200Two-component response regulator [DesK]; Member of the two-component regulatory system DesR/DesK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase.
yocH protein networkhttps://string-db.org/network/224308.BSU19210Putative exported cell wall-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
rtbI protein networkhttps://string-db.org/network/224308.BSU19220Ribonuclease toxin of toxin-antitoxin systems RttI-RttJ; Probable DNA helicase. Required for DNA repair and intramolecular recombination; probably has overlapping function with RecS (AC P50729). [...]
rtbJ protein networkhttps://string-db.org/network/224308.BSU19230Antitoxin of ribonuclease RttI; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its acti [...]
yocK protein networkhttps://string-db.org/network/224308.BSU19240Putative general stress protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
yocL protein networkhttps://string-db.org/network/224308.BSU19250Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoyB protein networkhttps://string-db.org/network/224308.BSU19259Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 19383706, 20709900.
yocM protein networkhttps://string-db.org/network/224308.BSU19260Putative spore coat protein; Part of the cellular protein quality control system with a specific role in salt stress response. May facilitate protein homeostasis, together with chemical chaperone [...]
yozN protein networkhttps://string-db.org/network/224308.BSU19270Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yocN protein networkhttps://string-db.org/network/224308.BSU19280Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yozO protein networkhttps://string-db.org/network/224308.BSU19290Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yozC protein networkhttps://string-db.org/network/224308.BSU19300Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
dhaS protein networkhttps://string-db.org/network/224308.BSU19310Putative aldehyde dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs t [...]
sqhC protein networkhttps://string-db.org/network/224308.BSU19320Squalene-hopene cyclase; Catalyzes the cyclization of tetraprenyl beta-curcumene into sporulenol; Belongs to the terpene cyclase/mutase family.
sodF protein networkhttps://string-db.org/network/224308.BSU19330Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
yocR protein networkhttps://string-db.org/network/224308.BSU19340Putative sodium-dependent transporter; Putative sodium-dependent transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
yocS protein networkhttps://string-db.org/network/224308.BSU19350Putative sodium-dependent transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter [...]
odhB protein networkhttps://string-db.org/network/224308.BSU193602-oxoglutarate dehydrogenase complex (dihydrolipoamide transsuccinylase, E2 subunit); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conver [...]
odhA protein networkhttps://string-db.org/network/224308.BSU193702-oxoglutarate dehydrogenase (E1 subunit); E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion [...]
yojO protein networkhttps://string-db.org/network/224308.BSU19380Putative activator of nitric oxide reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regu [...]
yojN protein networkhttps://string-db.org/network/224308.BSU19390Putative nitric-oxide reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CbbQ/NirQ/N [...]
sodC protein networkhttps://string-db.org/network/224308.BSU19400Superoxide dismutase (exported lipoprotein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type lp: lipoprotein.
cwlS protein networkhttps://string-db.org/network/224308.BSU19410Peptidoglycan hydrolase (cell wall-binding d,l-endopeptidase); Probably functions as a cell separation enzyme in addition to LytE and LytF.
yojK protein networkhttps://string-db.org/network/224308.BSU19420Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
yojJ protein networkhttps://string-db.org/network/224308.BSU19430Putative enzyme with DAC domain; One of 3 paralogous diadenylate cyclases (DAC) in this bacteria, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP) (Probable). Upon exp [...]
norM protein networkhttps://string-db.org/network/224308.BSU19440MatE Na+-driven efflux family protein; Multidrug efflux pump; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
rsbRC protein networkhttps://string-db.org/network/224308.BSU19450Component of the piezosome (stressosome); One of 4 functionally non-identical RsbR paralogs, it functions in the environmental signaling branch of the general stress response.
bshBB protein networkhttps://string-db.org/network/224308.BSU19460Malate N-acetylglucosamine deacetylase (second enzyme); Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (Gl [...]
yojF protein networkhttps://string-db.org/network/224308.BSU19470Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yoyC protein networkhttps://string-db.org/network/224308.BSU19479Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yojE protein networkhttps://string-db.org/network/224308.BSU19480Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
gerT protein networkhttps://string-db.org/network/224308.BSU19490Component of the spore coat; Involved in spore germination; probably required at the earliest stage of germination.
yojB protein networkhttps://string-db.org/network/224308.BSU19510Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yojA protein networkhttps://string-db.org/network/224308.BSU19520Putative H+/anion permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
arxR protein networkhttps://string-db.org/network/224308.BSU19540Transcriptional repressor; Negatively regulates yodC and azoR1 which may contribute to the degradation of aromatic compounds. Probably positively regulates the catechol-specific transcription of [...]
yodC protein networkhttps://string-db.org/network/224308.BSU19550Putative oxidoreductase; Putative nitroreductase that may contribute to the degradation of aromatic compounds.
yodD protein networkhttps://string-db.org/network/224308.BSU19560Putative hydrolase; Putative hydrolase that may contribute to the degradation of aromatic compounds.
yodE protein networkhttps://string-db.org/network/224308.BSU19570Putative lyase/dioxygenase; Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds.
yoyD protein networkhttps://string-db.org/network/224308.BSU19579Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
yodF protein networkhttps://string-db.org/network/224308.BSU19580Putative Na+/metabolite permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Bel [...]
ctpA protein networkhttps://string-db.org/network/224308.BSU19590Carboxy-terminal processing protease; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.
yodH protein networkhttps://string-db.org/network/224308.BSU19600Putative S-adenosylmethionine-dependent methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: [...]
yodI protein networkhttps://string-db.org/network/224308.BSU19610Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yodJ protein networkhttps://string-db.org/network/224308.BSU19620D-alanyl-D-alanine carboxypeptidase lipoprotein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
deoD protein networkhttps://string-db.org/network/224308.BSU19630Purine nucleoside phosphorylase; Cleavage of adenosine and its derivatives; Belongs to the PNP/UDP phosphorylase family.
yoyE protein networkhttps://string-db.org/network/224308.BSU19639Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yodL protein networkhttps://string-db.org/network/224308.BSU19640Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yodM protein networkhttps://string-db.org/network/224308.BSU19650Putative phospholipid phosphatase; Catalyzes the dephosphorylation of phosphatidylglycerophosphate (PGP) to phosphatidylglycerol. Also has undecaprenyl pyrophosphate phosphatase activity, require [...]
yozD protein networkhttps://string-db.org/network/224308.BSU19660Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yoyF protein networkhttps://string-db.org/network/224308.BSU19669Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yodN protein networkhttps://string-db.org/network/224308.BSU19670Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yozE protein networkhttps://string-db.org/network/224308.BSU19680Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0346 family.
yokU protein networkhttps://string-db.org/network/224308.BSU19689Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
kamA protein networkhttps://string-db.org/network/224308.BSU19690Lysine 2,3-aminomutase; Catalyzes the interconversion of L-alpha-lysine and L-beta- lysine; Belongs to the radical SAM superfamily. KamA family.
kamB protein networkhttps://string-db.org/network/224308.BSU19700Epsilon-amino-beta-lysine acetyl transferase; In vitro, is able to catalyze the acetylation of beta-lysine to N6-acetyl-beta-lysine, an archaeal osmolyte produced by methanogenic archaea. Its phy [...]
yodQ protein networkhttps://string-db.org/network/224308.BSU19710Putative deacylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yodR protein networkhttps://string-db.org/network/224308.BSU19720Putative acyloate-acetoacetate CoA-transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative en [...]
yodS protein networkhttps://string-db.org/network/224308.BSU19730Putative aminoacyloate CoA-transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yodT protein networkhttps://string-db.org/network/224308.BSU19740Putative aminovalerate aminotransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yoyG protein networkhttps://string-db.org/network/224308.BSU19749Putative sporulation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
cgeE protein networkhttps://string-db.org/network/224308.BSU19750Protein involved in maturation of the outermost layer of the spore; May be involved in maturation of the outermost layer of the spore.
cgeD protein networkhttps://string-db.org/network/224308.BSU19760Protein involved in maturation of the outermost layer of the spore; May be involved in maturation of the outermost layer of the spore.
cgeC protein networkhttps://string-db.org/network/224308.BSU19770Protein involved in maturation of the outermost layer of the spore; May be involved in maturation of the outermost layer of the spore.
cgeA protein networkhttps://string-db.org/network/224308.BSU19780Spore outermost layer component; May be involved in maturation of the outermost layer of the spore.
cgeB protein networkhttps://string-db.org/network/224308.BSU19790Protein involved in maturation of the outermost layer of the spore; May be involved in maturation of the outermost layer of the spore.
phy protein networkhttps://string-db.org/network/224308.BSU19800Phytase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
yotN protein networkhttps://string-db.org/network/224308.BSU19820Putative capsular polysaccharide biosynthesis enzyme fragment; Evidence 7: Gene remnant; putative enzyme.
yotM protein networkhttps://string-db.org/network/224308.BSU19830Hypothetical protein; Evidence 5: No homology to any previously reported sequences; extrachromosomal origin.
yotL protein networkhttps://string-db.org/network/224308.BSU19840Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yotK protein networkhttps://string-db.org/network/224308.BSU19850Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yotJ protein networkhttps://string-db.org/network/224308.BSU19860Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yotI protein networkhttps://string-db.org/network/224308.BSU19870Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yotH protein networkhttps://string-db.org/network/224308.BSU19880Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yotG protein networkhttps://string-db.org/network/224308.BSU19890Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yotF protein networkhttps://string-db.org/network/224308.BSU19900Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yotE protein networkhttps://string-db.org/network/224308.BSU19910Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yotD protein networkhttps://string-db.org/network/224308.BSU19920Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yotC protein networkhttps://string-db.org/network/224308.BSU19930Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yotB protein networkhttps://string-db.org/network/224308.BSU19940Putative metallo-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
sspC protein networkhttps://string-db.org/network/224308.BSU19950Small acid-soluble spore protein (alpha/beta-type SASP); SASP are bound to spore DNA. They are double-stranded DNA- binding proteins that cause DNA to change to an a-like conformation. They prote [...]
yosX protein networkhttps://string-db.org/network/224308.BSU19970Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yosW protein networkhttps://string-db.org/network/224308.BSU19980Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yosV protein networkhttps://string-db.org/network/224308.BSU19990Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yojW protein networkhttps://string-db.org/network/224308.BSU19999Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yosU protein networkhttps://string-db.org/network/224308.BSU20000Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yosT protein networkhttps://string-db.org/network/224308.BSU20010Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yosS protein networkhttps://string-db.org/network/224308.BSU20020SPbeta phage deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decrease [...]
yosR protein networkhttps://string-db.org/network/224308.BSU20030SPbeta phage putative thiol disulfide oxidoreductase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; Belongs to the thioredoxin [...]
yosP protein networkhttps://string-db.org/network/224308.BSU20040Ribonucleoside-diphosphate reductase 2, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotide [...]
yosQ protein networkhttps://string-db.org/network/224308.BSU20050SPbeta phage endodeoxyribonuclease (homing endonuclease, responsible for intron mobility); A possible homing endonuclease, it is entirely encoded within the YosP intron.
nrdEB protein networkhttps://string-db.org/network/224308.BSU20060SPbeta phage ribonucleoside reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [...]
nrdIB protein networkhttps://string-db.org/network/224308.BSU20070SPbeta phage subunit of nucleoside diphosphate reductase; Probably involved in ribonucleotide reductase function.
yosL protein networkhttps://string-db.org/network/224308.BSU20080Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yosK protein networkhttps://string-db.org/network/224308.BSU20090Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yosJ protein networkhttps://string-db.org/network/224308.BSU20100Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yosI protein networkhttps://string-db.org/network/224308.BSU20110Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yosH protein networkhttps://string-db.org/network/224308.BSU20120Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yosG protein networkhttps://string-db.org/network/224308.BSU20130Putative cell wall hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yosF protein networkhttps://string-db.org/network/224308.BSU20140Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yosE protein networkhttps://string-db.org/network/224308.BSU20150Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yosD protein networkhttps://string-db.org/network/224308.BSU20160Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yosC protein networkhttps://string-db.org/network/224308.BSU20170Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yosB protein networkhttps://string-db.org/network/224308.BSU20180Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yosA protein networkhttps://string-db.org/network/224308.BSU20190Putative type I toxin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
yorZ protein networkhttps://string-db.org/network/224308.BSU20200Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorY protein networkhttps://string-db.org/network/224308.BSU20210Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorX protein networkhttps://string-db.org/network/224308.BSU20220Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorW protein networkhttps://string-db.org/network/224308.BSU20230Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorV protein networkhttps://string-db.org/network/224308.BSU20240Putative nucleic acid binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
mtbP protein networkhttps://string-db.org/network/224308.BSU20250DNA (cytosine-5-)-methyltransferase; This enzyme methylates the first cytosine within the sequences GGCC and GCNGC; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methy [...]
yorT protein networkhttps://string-db.org/network/224308.BSU20260Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorS protein networkhttps://string-db.org/network/224308.BSU20270Conserved hypothetical protein; Dephosphorylates nucleoside monophosphates such as the 5' and 2'(3')-phosphates of deoxyribonucleotides in vitro. Also catalyzes the dephosphorylation of coenzyme [...]
yorR protein networkhttps://string-db.org/network/224308.BSU20280Putative nucleotide kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yorQ protein networkhttps://string-db.org/network/224308.BSU20290Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorP protein networkhttps://string-db.org/network/224308.BSU20300Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorO protein networkhttps://string-db.org/network/224308.BSU20310Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorN protein networkhttps://string-db.org/network/224308.BSU20320Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorM protein networkhttps://string-db.org/network/224308.BSU20330Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yorL protein networkhttps://string-db.org/network/224308.BSU20340Putative DNA polymerase; Probable DNA polymerase; Belongs to the DNA polymerase type-C family.
yorK protein networkhttps://string-db.org/network/224308.BSU20350Putative single-strand DNA-specific exonuclease; Putative single-stranded-DNA-specific exonuclease.
yorJ protein networkhttps://string-db.org/network/224308.BSU20360Putative DNA replication initiation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzym [...]
yorI protein networkhttps://string-db.org/network/224308.BSU20370Putative replicative DNA helicase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yorH protein networkhttps://string-db.org/network/224308.BSU20380Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorG protein networkhttps://string-db.org/network/224308.BSU20390Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorF protein networkhttps://string-db.org/network/224308.BSU20400Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorE protein networkhttps://string-db.org/network/224308.BSU20410Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorD protein networkhttps://string-db.org/network/224308.BSU20420Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorC protein networkhttps://string-db.org/network/224308.BSU20430Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yorB protein networkhttps://string-db.org/network/224308.BSU20440Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yorA protein networkhttps://string-db.org/network/224308.BSU20450Putative capsid component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure.
yoqZ protein networkhttps://string-db.org/network/224308.BSU20460Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0714 family.
yoqY protein networkhttps://string-db.org/network/224308.BSU20470Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoqX protein networkhttps://string-db.org/network/224308.BSU20480Putative SPbeta phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
yoqW protein networkhttps://string-db.org/network/224308.BSU20490Conserved hypothetical protein; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Recognizes and binds ab [...]
ligB protein networkhttps://string-db.org/network/224308.BSU20500Bacteriophage SPbeta DNA ligase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; Belongs to the ATP-dependent DNA ligase family.
yoqU protein networkhttps://string-db.org/network/224308.BSU20510Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yoqT protein networkhttps://string-db.org/network/224308.BSU20520Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoqS protein networkhttps://string-db.org/network/224308.BSU20530Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoqR protein networkhttps://string-db.org/network/224308.BSU20540Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoqP protein networkhttps://string-db.org/network/224308.BSU20550Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoqO protein networkhttps://string-db.org/network/224308.BSU20560Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
yoqN protein networkhttps://string-db.org/network/224308.BSU20570Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoqM protein networkhttps://string-db.org/network/224308.BSU20580Putative membrane bound protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane componen [...]
yoqL protein networkhttps://string-db.org/network/224308.BSU20590Putative endonuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the HNH [...]
yoqK protein networkhttps://string-db.org/network/224308.BSU20600Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoqJ protein networkhttps://string-db.org/network/224308.BSU20610Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yoqI protein networkhttps://string-db.org/network/224308.BSU20620Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yoqH protein networkhttps://string-db.org/network/224308.BSU20630Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yoqG protein networkhttps://string-db.org/network/224308.BSU20640Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoqF protein networkhttps://string-db.org/network/224308.BSU20650Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoqE protein networkhttps://string-db.org/network/224308.BSU20660Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoqD protein networkhttps://string-db.org/network/224308.BSU20670Putative DNA-binding protein anti-repressor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
yoqC protein networkhttps://string-db.org/network/224308.BSU20680Putative nucleotide-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
yoqB protein networkhttps://string-db.org/network/224308.BSU20690Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoqA protein networkhttps://string-db.org/network/224308.BSU20700Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yopZ protein networkhttps://string-db.org/network/224308.BSU20710Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yopY protein networkhttps://string-db.org/network/224308.BSU20720Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yopX protein networkhttps://string-db.org/network/224308.BSU20730Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yopW protein networkhttps://string-db.org/network/224308.BSU20740Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yopV protein networkhttps://string-db.org/network/224308.BSU20750Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yopU protein networkhttps://string-db.org/network/224308.BSU20760Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yopT protein networkhttps://string-db.org/network/224308.BSU20770Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yopS protein networkhttps://string-db.org/network/224308.BSU20780Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
yopR protein networkhttps://string-db.org/network/224308.BSU20790Putative integrase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yopQ protein networkhttps://string-db.org/network/224308.BSU20800Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yopP protein networkhttps://string-db.org/network/224308.BSU20810Putative phage integrase; Probable recombinase that does not seem to have a role in chromosome dimer resolution per se but rather may have some facilitative role during chromosome partitioning in [...]
yopO protein networkhttps://string-db.org/network/224308.BSU20820Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
yopN protein networkhttps://string-db.org/network/224308.BSU20830Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yopM protein networkhttps://string-db.org/network/224308.BSU20840Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yopL protein networkhttps://string-db.org/network/224308.BSU20850Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yopK protein networkhttps://string-db.org/network/224308.BSU20860Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yopJ protein networkhttps://string-db.org/network/224308.BSU20870Putative nucleotide binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
yopI protein networkhttps://string-db.org/network/224308.BSU20880Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yopH protein networkhttps://string-db.org/network/224308.BSU20890Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yopG protein networkhttps://string-db.org/network/224308.BSU20900Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yopF protein networkhttps://string-db.org/network/224308.BSU20910Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yopE protein networkhttps://string-db.org/network/224308.BSU20920Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoyH protein networkhttps://string-db.org/network/224308.BSU20928Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yoyI protein networkhttps://string-db.org/network/224308.BSU20929Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yopD protein networkhttps://string-db.org/network/224308.BSU20930Putative conserved hypothetical membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative [...]
yopC protein networkhttps://string-db.org/network/224308.BSU20940Conserved hypothetical protein; May be the toxic component of a type II toxin-antitoxin (TA) system. Neutralized by its cognate antitoxin YopB. In the C-terminal section; belongs to the MbcT/ParT [...]
yopB protein networkhttps://string-db.org/network/224308.BSU20950Putative transcriptional regulator; May be the antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the activity of cognate toxin YopC.
yopA protein networkhttps://string-db.org/network/224308.BSU20960Putative methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yonX protein networkhttps://string-db.org/network/224308.BSU20970Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yonV protein networkhttps://string-db.org/network/224308.BSU20980Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yonU protein networkhttps://string-db.org/network/224308.BSU20990Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yoyJ protein networkhttps://string-db.org/network/224308.BSU20999Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yonT protein networkhttps://string-db.org/network/224308.BSU21000Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yonS protein networkhttps://string-db.org/network/224308.BSU21010Putative glycosyl hydrolase lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yonR protein networkhttps://string-db.org/network/224308.BSU21020Putative transcriptional regulator (Xre family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative r [...]
yonP protein networkhttps://string-db.org/network/224308.BSU21030Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yonO protein networkhttps://string-db.org/network/224308.BSU21040Conserved hypothetical protein; A single subunit DNA-dependent RNA polymerase (RNAP) that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates (rNTPs) as substr [...]
yonN protein networkhttps://string-db.org/network/224308.BSU21050Putative HU-related DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental condit [...]
yonK protein networkhttps://string-db.org/network/224308.BSU21060Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yonJ protein networkhttps://string-db.org/network/224308.BSU21070Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yonI protein networkhttps://string-db.org/network/224308.BSU21080Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yonH protein networkhttps://string-db.org/network/224308.BSU21090Putative capsid protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure.
yonG protein networkhttps://string-db.org/network/224308.BSU21100Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yonF protein networkhttps://string-db.org/network/224308.BSU21110Putative prophage terminase, ATP subunit; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yonE protein networkhttps://string-db.org/network/224308.BSU21120Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yonD protein networkhttps://string-db.org/network/224308.BSU21130Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yonC protein networkhttps://string-db.org/network/224308.BSU21140Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yonB protein networkhttps://string-db.org/network/224308.BSU21150Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yonA protein networkhttps://string-db.org/network/224308.BSU21160Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yomZ protein networkhttps://string-db.org/network/224308.BSU21170Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yomY protein networkhttps://string-db.org/network/224308.BSU21180Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yomX protein networkhttps://string-db.org/network/224308.BSU21190Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yomW protein networkhttps://string-db.org/network/224308.BSU21200Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yomV protein networkhttps://string-db.org/network/224308.BSU21210Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yomU protein networkhttps://string-db.org/network/224308.BSU21220Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
youA protein networkhttps://string-db.org/network/224308.BSU21229Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yomT protein networkhttps://string-db.org/network/224308.BSU21230Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yomS protein networkhttps://string-db.org/network/224308.BSU21240Putative phage-related lytic exoenzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yomR protein networkhttps://string-db.org/network/224308.BSU21250Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yomQ protein networkhttps://string-db.org/network/224308.BSU21260Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yomP protein networkhttps://string-db.org/network/224308.BSU21270Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yomO protein networkhttps://string-db.org/network/224308.BSU21280Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yomN protein networkhttps://string-db.org/network/224308.BSU21290Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yomM protein networkhttps://string-db.org/network/224308.BSU21300Putative integrase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the 'phage' [...]
yozP protein networkhttps://string-db.org/network/224308.BSU21310Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yomL protein networkhttps://string-db.org/network/224308.BSU21320Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
youB protein networkhttps://string-db.org/network/224308.BSU21329Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10931276.
yomK protein networkhttps://string-db.org/network/224308.BSU21330Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yomJ protein networkhttps://string-db.org/network/224308.BSU21340Putative phage immunity protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
cwlP protein networkhttps://string-db.org/network/224308.BSU21350Lytic transglycosylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; Belongs to the transglycosylase Slt family.
yomH protein networkhttps://string-db.org/network/224308.BSU21360Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yomG protein networkhttps://string-db.org/network/224308.BSU21370Hypothetical protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin.
yomF protein networkhttps://string-db.org/network/224308.BSU21380Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yomE protein networkhttps://string-db.org/network/224308.BSU21390Putative glycosyl hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yomD protein networkhttps://string-db.org/network/224308.BSU21400Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
blyA protein networkhttps://string-db.org/network/224308.BSU21410Bacteriophage SPbeta N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transfo [...]
bhlA protein networkhttps://string-db.org/network/224308.BSU21420Bacteriophage SPbeta holin-like protein; May be involved in the secretion of the autolysin BlyA.
bhlB protein networkhttps://string-db.org/network/224308.BSU21430Holin-like bacteriophage SPbeta protein; May be involved in the secretion of the autolysin BlyA; Belongs to the SPP1 holin family.
bdbB protein networkhttps://string-db.org/network/224308.BSU21440Bacteriophage SPbeta thiol-disulfide oxidoreductase; Important but not absolutely essential for the production of the lantibiotic sublancin 168, it may also be required for the stability of other [...]
sunS protein networkhttps://string-db.org/network/224308.BSU21450Sublancin glycosyltransferase; Transfers a hexose moiety onto 'Cys-41' of bacteriocin sublancin-168 (SunA). Accepts UDP-glucose (UDP-Glc), UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-galactose (UD [...]
bdbA protein networkhttps://string-db.org/network/224308.BSU21460Bacteriophage SPbeta thiol-disulfide oxidoreductase; Unknown; dispensable for production of the lantibiotic sublancin 168 and for competence for DNA uptake; Belongs to the thioredoxin family.
sunT protein networkhttps://string-db.org/network/224308.BSU21470Sublancin 168 lantibiotic transporter; SunT (TC 3.A.1.112.4) is required for production of the lantibiotic sublancin-168, probably by both processing the signal peptide and exporting the resultin [...]
sunA protein networkhttps://string-db.org/network/224308.BSU21480Sublancin 168 lantibiotic antimicrobial precursor peptide in SPBeta prophage; Bacteriocin active against Gram-positive bacteria. Inhibits B.cereus spore outgrowth, after the germination stage, ap [...]
sunI protein networkhttps://string-db.org/network/224308.BSU21490Protein of immunity to sublancin; Is essential and sufficient to confer resistance to the bacteriocin sublancin 168.
uvrX protein networkhttps://string-db.org/network/224308.BSU21500Lesion bypass phage DNA polymerase; Evidence 2b: Function of strongly homologous gene; enzyme.
yolD protein networkhttps://string-db.org/network/224308.BSU21510Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951.
yolC protein networkhttps://string-db.org/network/224308.BSU21520SP beta phage protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin.
yolB protein networkhttps://string-db.org/network/224308.BSU21530Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yolA protein networkhttps://string-db.org/network/224308.BSU21540Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
bsrG protein networkhttps://string-db.org/network/224308.BSU21546Phage toxin; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type m: membrane component.
yokL protein networkhttps://string-db.org/network/224308.BSU21550Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the [...]
yokK protein networkhttps://string-db.org/network/224308.BSU21560Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yokJ protein networkhttps://string-db.org/network/224308.BSU21570Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the ability to inhibit growth of cognate toxin YokI upon expression in E.coli. Does not h [...]
yokI protein networkhttps://string-db.org/network/224308.BSU21580Putative DNA wielding protein; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 449-571) inhibits growth upon expression in E.coli which is neutralized by cognat [...]
yokH protein networkhttps://string-db.org/network/224308.BSU21590Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yokG protein networkhttps://string-db.org/network/224308.BSU21600Putative transposase fragment; Evidence 7: Gene remnant; putative enzyme; Belongs to the cry6A endotoxin family.
yokF protein networkhttps://string-db.org/network/224308.BSU21610SPbeta phage DNA nuclease, lipoprotein; Catalyzes the hydrolysis of supercoiled double and single strand DNA and RNA. Involved in chromosomal DNA degradation and cell death caused by thermal stre [...]
yokE protein networkhttps://string-db.org/network/224308.BSU21620Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yokD protein networkhttps://string-db.org/network/224308.BSU21630Aminoglycoside N3'-acetyltransferase; May contribute to antibiotic resistance; Belongs to the antibiotic N-acetyltransferase family.
yokC protein networkhttps://string-db.org/network/224308.BSU21640Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10376821.
yokB protein networkhttps://string-db.org/network/224308.BSU21650Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 10376821.
yokA protein networkhttps://string-db.org/network/224308.BSU21660Putative DNA recombinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; In the N-termina [...]
msrB protein networkhttps://string-db.org/network/224308.BSU21680Putative capsular polysaccharide biosynthesis enzyme fragment; Evidence 7: Gene remnant; putative enzyme.
msrA protein networkhttps://string-db.org/network/224308.BSU21690Peptide methionine S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methio [...]
ypoP protein networkhttps://string-db.org/network/224308.BSU21700Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
dinF protein networkhttps://string-db.org/network/224308.BSU21710Damage inducible, Na+ driven multidrug efflux pump; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; transporter.
ypmT protein networkhttps://string-db.org/network/224308.BSU21720Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ypmS protein networkhttps://string-db.org/network/224308.BSU21730Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ypmR protein networkhttps://string-db.org/network/224308.BSU21740Putative exported lipase/acylhydrolase (lipoprotein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putat [...]
scuA protein networkhttps://string-db.org/network/224308.BSU21750Assembly factor BSco of the Cu(A) site of cytochrome c oxidase; Necessary for insertion of copper into the active site of cytochrome c oxidase. May play a role in copper homeostasis or redox sign [...]
ypmP protein networkhttps://string-db.org/network/224308.BSU21760Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15060025.
ilvA protein networkhttps://string-db.org/network/224308.BSU21770Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a producti [...]
yplP protein networkhttps://string-db.org/network/224308.BSU21780Transcriptional enhancer; May play a role in cold adaptation.
yplQ protein networkhttps://string-db.org/network/224308.BSU21790Putative membrane hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ypkP protein networkhttps://string-db.org/network/224308.BSU21800Putative acyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
dfrA protein networkhttps://string-db.org/network/224308.BSU21810Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
thyB protein networkhttps://string-db.org/network/224308.BSU21820Thymidylate synthase B; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate [...]
ypjQ protein networkhttps://string-db.org/network/224308.BSU21830Putative phosphatidylglycerophosphatase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; To B.subtilis YutG [...]
ypjP protein networkhttps://string-db.org/network/224308.BSU21840Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ypiP protein networkhttps://string-db.org/network/224308.BSU21850Putative methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
bshR protein networkhttps://string-db.org/network/224308.BSU21860Protein disulfide isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the UPF0403 family.
ilvD protein networkhttps://string-db.org/network/224308.BSU21870Dihydroxy-acid dehydratase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the IlvD/Edd family.
ypgR protein networkhttps://string-db.org/network/224308.BSU21880Putative lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ypgQ protein networkhttps://string-db.org/network/224308.BSU21890Putative metal-dependent phosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
bsaA protein networkhttps://string-db.org/network/224308.BSU21900Putative bacillithiol peroxidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs [...]
metA protein networkhttps://string-db.org/network/224308.BSU21910Putative homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
ugtP protein networkhttps://string-db.org/network/224308.BSU21920UDP-glucose diacylglyceroltransferase; Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively trans [...]
cspD protein networkhttps://string-db.org/network/224308.BSU21930Cold-shock protein, molecular chaperone, RNA-helicase co-factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
degR protein networkhttps://string-db.org/network/224308.BSU21940Activation of degradative enzymes (aprE, nprE, sacB) production or activity; Stabilizes the phosphorylated form of DegU, leading to enhanced production of levansucrase, alkaline protease, and neu [...]
ypzA protein networkhttps://string-db.org/network/224308.BSU21950Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ypeQ protein networkhttps://string-db.org/network/224308.BSU21960Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ypeP protein networkhttps://string-db.org/network/224308.BSU21970Ribonuclease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
ypdP protein networkhttps://string-db.org/network/224308.BSU21980Putative integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q [...]
ypdQ protein networkhttps://string-db.org/network/224308.BSU21990Putative RNA binding protein; Not known; does not have RNase H activity; Belongs to the RNase H family. EbsB subfamily.
sspL protein networkhttps://string-db.org/network/224308.BSU22000Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
ypcP protein networkhttps://string-db.org/network/224308.BSU220105'3'-exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA.
ypzF protein networkhttps://string-db.org/network/224308.BSU22019Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ypbS protein networkhttps://string-db.org/network/224308.BSU22020Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
dynA protein networkhttps://string-db.org/network/224308.BSU22030Dynamin-like GTPase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
fbpC protein networkhttps://string-db.org/network/224308.BSU22036Regulator of iron homeostasis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
bpsB protein networkhttps://string-db.org/network/224308.BSU22040Alkylpyrone methyltransferase BpsB; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme.
bpsA protein networkhttps://string-db.org/network/224308.BSU22050Promiscuous alkylpyrone synthase BpsA; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
pbuX protein networkhttps://string-db.org/network/224308.BSU22060Xanthine permease; Transport of xanthine in the cell; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily.
xpt protein networkhttps://string-db.org/network/224308.BSU22070Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so that it can be reused for RNA or DNA synthe [...]
ypwA protein networkhttps://string-db.org/network/224308.BSU22080Metal-dependent carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. Has lower ac [...]
kdgT protein networkhttps://string-db.org/network/224308.BSU220902-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hy [...]
kdgA protein networkhttps://string-db.org/network/224308.BSU221002-keto-3-deoxygluconate-6-phosphate aldolase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
kdgK protein networkhttps://string-db.org/network/224308.BSU221102-keto-3-deoxygluconate kinase; Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG). Belongs to the carbohydrate kinase PfkB family.
kdgR protein networkhttps://string-db.org/network/224308.BSU22120Kdg operon transcriptional regulator (LacI family); Transcriptional repressor of the kdgRKAT and kduID operons for pectin utilization.
kduI protein networkhttps://string-db.org/network/224308.BSU221304-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
kduD protein networkhttps://string-db.org/network/224308.BSU221402-keto-3-deoxygluconate oxidoreductase; Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3-deoxygluconate (KDG or 2-dehydro-3-deoxyglu [...]
ypvA protein networkhttps://string-db.org/network/224308.BSU22150Putative ATP-dependent helicase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yptA protein networkhttps://string-db.org/network/224308.BSU22160Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ypzG protein networkhttps://string-db.org/network/224308.BSU22169Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ypsC protein networkhttps://string-db.org/network/224308.BSU22170Putative methylase with RNA interaction domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative en [...]
gpsB protein networkhttps://string-db.org/network/224308.BSU22180Cell division protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisom [...]
ypsA protein networkhttps://string-db.org/network/224308.BSU22190Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0398 family.
cotD protein networkhttps://string-db.org/network/224308.BSU22200Spore coat protein (inner); Evidence 1a: Function experimentally demonstrated in the studied strain; cell process.
yprB protein networkhttps://string-db.org/network/224308.BSU22210Putative nucleic acid binding enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yprA protein networkhttps://string-db.org/network/224308.BSU22220Putative ATP-dependent helicase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs t [...]
ypqE protein networkhttps://string-db.org/network/224308.BSU22230Putative phosphotransferase system enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes th [...]
ypqA protein networkhttps://string-db.org/network/224308.BSU22240Hypothetical protein; Evidence 5: No homology to any previously reported sequences; Belongs to the small heat shock protein (HSP20) family.
yppG protein networkhttps://string-db.org/network/224308.BSU22250Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yppF protein networkhttps://string-db.org/network/224308.BSU22260Putative site-specific integrase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
yppE protein networkhttps://string-db.org/network/224308.BSU22270Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yppD protein networkhttps://string-db.org/network/224308.BSU22280Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15687200.
sspM protein networkhttps://string-db.org/network/224308.BSU22290Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
yppC protein networkhttps://string-db.org/network/224308.BSU22300Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
recU protein networkhttps://string-db.org/network/224308.BSU22310Holliday junction resolvase; Has at least 2 separable functions; Holliday junction resolution with generation of monomeric chromosomes, and modulation of RecA activity. Endonuclease that resolves [...]
ponA protein networkhttps://string-db.org/network/224308.BSU22320Peptidoglycan glycosyltransferase (penicillin-binding proteins 1A and 1B); Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-i [...]
ypoC protein networkhttps://string-db.org/network/224308.BSU22330Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
nth protein networkhttps://string-db.org/network/224308.BSU22340Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- [...]
dnaD protein networkhttps://string-db.org/network/224308.BSU22350DNA-remodelling primosomal protein; Probable component of primosome involved in the initiation of DNA replication.
asnS protein networkhttps://string-db.org/network/224308.BSU22360asparaginyl-tRNA synthetase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
aspB protein networkhttps://string-db.org/network/224308.BSU22370Putative aspartate aminotransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belon [...]
ypmB protein networkhttps://string-db.org/network/224308.BSU22380Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ypmA protein networkhttps://string-db.org/network/224308.BSU22390Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
dinG protein networkhttps://string-db.org/network/224308.BSU22400Damage inducible ATP-dependent 3'->5' nuclease; 3'-5' exonuclease.
panD protein networkhttps://string-db.org/network/224308.BSU22410Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
panC protein networkhttps://string-db.org/network/224308.BSU22420Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
panB protein networkhttps://string-db.org/network/224308.BSU22430Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopa [...]
birA protein networkhttps://string-db.org/network/224308.BSU22440Biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
cca protein networkhttps://string-db.org/network/224308.BSU22450tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order [...]
bshA protein networkhttps://string-db.org/network/224308.BSU22460Malate glycosyltransferase for bacillithiol synthesis; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway, the formation of N-acetylglucosaminylmalate (GlcNAc-Ma [...]
bshBA protein networkhttps://string-db.org/network/224308.BSU22470Malate N-acetylglucosamine N-acetyl hydrolase; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) [...]
mgsA protein networkhttps://string-db.org/network/224308.BSU22480Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
dapB protein networkhttps://string-db.org/network/224308.BSU22490(4S)-4-hydroxy-2,3,4, 5-tetrahydro-(2S)-dipicolinic acid (HTPA) dehydratase reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
ypjD protein networkhttps://string-db.org/network/224308.BSU22500Nucleotide phosphohydrolase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
ypjC protein networkhttps://string-db.org/network/224308.BSU22510Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ypjB protein networkhttps://string-db.org/network/224308.BSU22520Spore formation membrane associated protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type m: membrane component.
ypjA protein networkhttps://string-db.org/network/224308.BSU22530Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
qcrC protein networkhttps://string-db.org/network/224308.BSU22540Menaquinol:cytochrome c oxidoreductase (cytochrome cc subunit); Component of the menaquinol-cytochrome c reductase complex.
qcrB protein networkhttps://string-db.org/network/224308.BSU22550Menaquinol:cytochrome c oxidoreductase (cytochrome b subunit); Component of the menaquinol-cytochrome c reductase complex.
qcrA protein networkhttps://string-db.org/network/224308.BSU22560Menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit); Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein.
ypiF protein networkhttps://string-db.org/network/224308.BSU22570Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ypiB protein networkhttps://string-db.org/network/224308.BSU22580Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16847875; Belongs to the UPF0302 family.
ypiA protein networkhttps://string-db.org/network/224308.BSU22590Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
aroA protein networkhttps://string-db.org/network/224308.BSU226003-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvoylshikimate-3-phosphate synthase); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shi [...]
tyrA protein networkhttps://string-db.org/network/224308.BSU22610Prephenate dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the prephenate/arogenate dehydrogenase family.
hisC protein networkhttps://string-db.org/network/224308.BSU22620Histidinol-phosphate aminotransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-II pyridoxal-phosphate-dependent amino [...]
trpA protein networkhttps://string-db.org/network/224308.BSU22630Tryptophan synthase (alpha subunit); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate; Belongs to the TrpA family.
trpB protein networkhttps://string-db.org/network/224308.BSU22640Tryptophan synthase (beta subunit); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpF protein networkhttps://string-db.org/network/224308.BSU22650Phosphoribosyl anthranilate isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the TrpF family.
trpD protein networkhttps://string-db.org/network/224308.BSU22670Indole-3-glycerol phosphate synthase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate [...]
trpE protein networkhttps://string-db.org/network/224308.BSU22680Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the gl [...]
aroH protein networkhttps://string-db.org/network/224308.BSU22690Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
aroB protein networkhttps://string-db.org/network/224308.BSU227003-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquin [...]
aroF protein networkhttps://string-db.org/network/224308.BSU22710Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
cheR protein networkhttps://string-db.org/network/224308.BSU22720Methyl-accepting chemotaxis proteins (MCPs) methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. Ch [...]
ndk protein networkhttps://string-db.org/network/224308.BSU22730Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, [...]
hepT protein networkhttps://string-db.org/network/224308.BSU22740Heptaprenyl diphosphate synthase component II; Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7). Belongs to the FPP/GGPP synthase [...]
menH protein networkhttps://string-db.org/network/224308.BSU22750Menaquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
hepS protein networkhttps://string-db.org/network/224308.BSU22760Heptaprenyl diphosphate synthase component I; Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7).
mtrB protein networkhttps://string-db.org/network/224308.BSU22770Tryptophan operon RNA-binding attenuation protein (TRAP); Required for transcription attenuation control in the trp operon. This trans-acting factor binds to trinucleotide repeats (GAG or UAG) lo [...]
folEA protein networkhttps://string-db.org/network/224308.BSU22780GTP cyclohydrolase I; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the GTP cyclohydrolase I family.
hbs protein networkhttps://string-db.org/network/224308.BSU22790Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditio [...]
spoIVA protein networkhttps://string-db.org/network/224308.BSU22800Morphogenetic stage IV sporulation protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Its ATP hydrolysis is required for proper assembly of the spo [...]
yphF protein networkhttps://string-db.org/network/224308.BSU22810Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
yphE protein networkhttps://string-db.org/network/224308.BSU22820Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
gpsA protein networkhttps://string-db.org/network/224308.BSU22830NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Involved in the biosynthesis of the sn-glycerol 3-phosphate required for phospholipid synthesis.
engA protein networkhttps://string-db.org/network/224308.BSU22840GTPase essential for ribosome 50S subunit assembly; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase [...]
ypzH protein networkhttps://string-db.org/network/224308.BSU22849Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yphB protein networkhttps://string-db.org/network/224308.BSU22850Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yphA protein networkhttps://string-db.org/network/224308.BSU22860Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ypzI protein networkhttps://string-db.org/network/224308.BSU22869Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
fni protein networkhttps://string-db.org/network/224308.BSU22870Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimet [...]
rpfA protein networkhttps://string-db.org/network/224308.BSU22880RNA degradation presenting factor (ribosomal protein S1 homolog); Plays a role in sporulation; Belongs to the bacterial ribosomal protein bS1 family.
cmk protein networkhttps://string-db.org/network/224308.BSU22890Cytidylate kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme.
ypfB protein networkhttps://string-db.org/network/224308.BSU22900Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ypfA protein networkhttps://string-db.org/network/224308.BSU22910Putative cyclic diGMP binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
ypeB protein networkhttps://string-db.org/network/224308.BSU22920Spore membrane component; Required for spore cortex hydrolysis during germination. Appears to be required for either expression, localization, activation or function of SleB.
sleB protein networkhttps://string-db.org/network/224308.BSU22930Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components.
prsW protein networkhttps://string-db.org/network/224308.BSU22940Protease required for RsiW anti-sigma(W) degradation; Involved in the degradation of anti-sigma-W factor RsiW. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after t [...]
ypdA protein networkhttps://string-db.org/network/224308.BSU22950Putative FAD-dependent disulfide oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative e [...]
gudB protein networkhttps://string-db.org/network/224308.BSU22960Cryptic glutamate dehydrogenase; GudB seems to be intrinsically inactive, however spontaneous mutations removing a 9-bp direct repeat within the wild-type gudB sequence activated the GudB protein [...]
mecB protein networkhttps://string-db.org/network/224308.BSU22970Regulator of competence and sporulation; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Also involved [...]
ypbG protein networkhttps://string-db.org/network/224308.BSU22980Putative phosphoesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
ypbF protein networkhttps://string-db.org/network/224308.BSU22990Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ypbE protein networkhttps://string-db.org/network/224308.BSU23000Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855244.
ypbD protein networkhttps://string-db.org/network/224308.BSU23010Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
recQ protein networkhttps://string-db.org/network/224308.BSU23020ATP-dependent DNA helicase; Probable DNA helicase. Required in synaptic and/or post- synaptic stages of recombination. Probably has overlapping function with RecQ (AC O34748). It probably acts to [...]
ypbB protein networkhttps://string-db.org/network/224308.BSU23030Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
fer protein networkhttps://string-db.org/network/224308.BSU23040Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. This ferredoxin may act as a phosphodonor to cytochrome P450 BioI.
fmnP protein networkhttps://string-db.org/network/224308.BSU23050FMN permease; Mediates uptake of riboflavin and roseoflavin, a toxic riboflavin analog; may also transport FMN. Probably a riboflavin- binding protein that interacts with the energy-coupling fact [...]
serA protein networkhttps://string-db.org/network/224308.BSU230703-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also [...]
aroC protein networkhttps://string-db.org/network/224308.BSU230803-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DH [...]
rsiX protein networkhttps://string-db.org/network/224308.BSU23090Negative regulator of sigma(X) activity; The anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigX, inhibits SigX activity and stabilizes it.
sigX protein networkhttps://string-db.org/network/224308.BSU23100RNA polymerase ECF(extracytoplasmic function)-type sigma factor sigma(X); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are t [...]
resE protein networkhttps://string-db.org/network/224308.BSU23110Two-component sensor histidine kinase; Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD [...]
resD protein networkhttps://string-db.org/network/224308.BSU23120Two-component response regulator; Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerob [...]
resC protein networkhttps://string-db.org/network/224308.BSU23130Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes.
resB protein networkhttps://string-db.org/network/224308.BSU23140Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes.
resA protein networkhttps://string-db.org/network/224308.BSU23150Extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein); Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May acc [...]
rluB protein networkhttps://string-db.org/network/224308.BSU23160Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-2633 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
spmB protein networkhttps://string-db.org/network/224308.BSU23170Spore maturation protein; Involved in spore core dehydration; might be involved in the transport of something into or out of the forespore or could be required for some modification of the cortex [...]
spmA protein networkhttps://string-db.org/network/224308.BSU23180Spore maturation protein; Involved in spore core dehydration; might be involved in the transport of something into or out of the forespore or could be required for some modification of the cortex [...]
dacB protein networkhttps://string-db.org/network/224308.BSU23190D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5*); Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Required specifically for the synthesis of the s [...]
ypuI protein networkhttps://string-db.org/network/224308.BSU23200Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12065423.
spcB protein networkhttps://string-db.org/network/224308.BSU23210Chromosome condensation and segregation factor; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull [...]
scpA protein networkhttps://string-db.org/network/224308.BSU23220Chromosome condensation and partitioning factor; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pul [...]
ypuF protein networkhttps://string-db.org/network/224308.BSU23230Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ypzK protein networkhttps://string-db.org/network/224308.BSU23240Putative acetyltransferase; Involved in riboflavin biosynthesis.
ribH protein networkhttps://string-db.org/network/224308.BSU232506,7-dimethyl-8-ribityllumazine synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone [...]
ribAB protein networkhttps://string-db.org/network/224308.BSU23260Fused GTP cyclohydrolase II and 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-ter [...]
ribE protein networkhttps://string-db.org/network/224308.BSU23270Riboflavin synthase (alpha subunit); Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil.
ribD protein networkhttps://string-db.org/network/224308.BSU23280Fused diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- ph [...]
ypuD protein networkhttps://string-db.org/network/224308.BSU23300Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
sipS protein networkhttps://string-db.org/network/224308.BSU23310Type I signal peptidase; Not essential for cell viability, but required for efficient secretion of many proteins.
ypzC protein networkhttps://string-db.org/network/224308.BSU23320Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ypzJ protein networkhttps://string-db.org/network/224308.BSU23328Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ypuB protein networkhttps://string-db.org/network/224308.BSU23340Hypothetical protein; Evidence 7: Gene remnant; PubMedId: 15849754, 16850406.
ypzD protein networkhttps://string-db.org/network/224308.BSU23350Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the GerPA/GerPF family.
ppiB protein networkhttps://string-db.org/network/224308.BSU23360Peptidyl-prolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type P [...]
ypuA protein networkhttps://string-db.org/network/224308.BSU23370Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
lysA protein networkhttps://string-db.org/network/224308.BSU23380Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
spoVAF protein networkhttps://string-db.org/network/224308.BSU23390Stage V sporulation protein AF; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
spoVAEA protein networkhttps://string-db.org/network/224308.BSU23401Stage V sporulation germinant protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
spoVAEB protein networkhttps://string-db.org/network/224308.BSU23402Spore germinant protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
spoVAD protein networkhttps://string-db.org/network/224308.BSU23410Stage V sporulation protein AD; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
spoVAC protein networkhttps://string-db.org/network/224308.BSU23420Stage V sporulation protein AC; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
spoVAB protein networkhttps://string-db.org/network/224308.BSU23430Stage V sporulation protein AB; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
spoVAA protein networkhttps://string-db.org/network/224308.BSU23440Stage V sporulation protein AA; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
sigF protein networkhttps://string-db.org/network/224308.BSU23450RNA polymerase sporulation-specific sigma factor (sigma-F); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. [...]
spoIIAB protein networkhttps://string-db.org/network/224308.BSU23460Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. [...]
spoIIAA protein networkhttps://string-db.org/network/224308.BSU23470Anti-anti-sigma factor (antagonist of SpoIIAB); In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition; Belongs to [...]
dacF protein networkhttps://string-db.org/network/224308.BSU23480D-alanyl-D-alanine carboxypeptidase (penicilin binding protein); Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.
pupG protein networkhttps://string-db.org/network/224308.BSU23490Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formati [...]
drm protein networkhttps://string-db.org/network/224308.BSU23500Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
ripX protein networkhttps://string-db.org/network/224308.BSU23510Site-specific tyrosine recombinase for chromosome partitioning; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- [...]
yqzK protein networkhttps://string-db.org/network/224308.BSU23519Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
fur protein networkhttps://string-db.org/network/224308.BSU23520Transcriptional regulator for iron transport and metabolism; Iron uptake repressor. Acts on the transcription of ferri- siderophore uptake genes.
spoIIM protein networkhttps://string-db.org/network/224308.BSU23530Autolysin component for dissolution of the septal cell wall (stage II sporulation); Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required [...]
yqkK protein networkhttps://string-db.org/network/224308.BSU23540Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
mleA protein networkhttps://string-db.org/network/224308.BSU23550NAD-dependent malic enzyme (conversion of malate into pyruvate); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
mleN protein networkhttps://string-db.org/network/224308.BSU23560malate-H+/Na+-lactate antiporter; Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport, in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role [...]
ansB protein networkhttps://string-db.org/network/224308.BSU23570L-aspartase (aspartate ammonia lyase); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-II fumarase/aspartase family. Aspartas [...]
ansA protein networkhttps://string-db.org/network/224308.BSU23580Exported L-asparaginase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the asparaginase 1 family.
ansR protein networkhttps://string-db.org/network/224308.BSU23590Transcriptional regulator of ansAB (Xre family); Transcriptional repressor for the ans operon coding for L- asparaginase and L-aspartase. NH4(+) may influence this repression.
yqxK protein networkhttps://string-db.org/network/224308.BSU23600Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To M.jannaschii MJ0043 N-terminal region.
nudF protein networkhttps://string-db.org/network/224308.BSU23610ADP-ribose pyrophosphatase; Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogeni [...]
mciZ protein networkhttps://string-db.org/network/224308.BSU23616Cell division factor; Blocks Z-ring formation in the mother cell during sporulation by inhibiting the polymerization of FtsZ. Binds to the minus end of FtsZ and functions as a filament-capping pr [...]
yqkF protein networkhttps://string-db.org/network/224308.BSU23620NADPH-dependent aldo-keto reductase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
yqkE protein networkhttps://string-db.org/network/224308.BSU23630Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqkD protein networkhttps://string-db.org/network/224308.BSU23640Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yqkC protein networkhttps://string-db.org/network/224308.BSU23650Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqkB protein networkhttps://string-db.org/network/224308.BSU23660Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqkA protein networkhttps://string-db.org/network/224308.BSU23670Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; In the C-terminal section; belongs to the UPF0157 (GrpB) family.
yqjZ protein networkhttps://string-db.org/network/224308.BSU23680Putative degradation enzyme (oxygenase); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yqjY protein networkhttps://string-db.org/network/224308.BSU23690Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yqjX protein networkhttps://string-db.org/network/224308.BSU23700Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951, 16267290.
polYB protein networkhttps://string-db.org/network/224308.BSU23710Y family DNA polymerase V bypassing lesions during replication; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks [...]
yqzH protein networkhttps://string-db.org/network/224308.BSU23720Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yqjV protein networkhttps://string-db.org/network/224308.BSU23730Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yqjU protein networkhttps://string-db.org/network/224308.BSU23740Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yqjT protein networkhttps://string-db.org/network/224308.BSU23750Putative lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
coaA protein networkhttps://string-db.org/network/224308.BSU23760Pantothenate kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type pe: putative enzyme.
dsdA protein networkhttps://string-db.org/network/224308.BSU23770D-serine ammonia-lyase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the serine/threonine dehydratase family. DsdA [...]
yqjQ protein networkhttps://string-db.org/network/224308.BSU23780Putative metabolite dehydrogenase, NAD-binding; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative en [...]
yqjP protein networkhttps://string-db.org/network/224308.BSU23790Putative metal-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
proI protein networkhttps://string-db.org/network/224308.BSU23800Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
yqjN protein networkhttps://string-db.org/network/224308.BSU23810Putative N-deacylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To B.subtilis RocB.
yqjM protein networkhttps://string-db.org/network/224308.BSU23820NADPH-dependent flavin oxidoreductase; Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and ni [...]
yqjL protein networkhttps://string-db.org/network/224308.BSU23830Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
rnz protein networkhttps://string-db.org/network/224308.BSU23840Ribosomal protein L31C pseudogene; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precu [...]
zwf protein networkhttps://string-db.org/network/224308.BSU23850Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
gndA protein networkhttps://string-db.org/network/224308.BSU23860NADP+-dependent 6-P-gluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. Is the p [...]
polYA protein networkhttps://string-db.org/network/224308.BSU23870DNA-damage lesion bypass DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo f [...]
mifM protein networkhttps://string-db.org/network/224308.BSU23880Regulator of OxaAB translation; Sensor protein that upregulates translation of the secondary membrane protein insertase (MisCB/YqjG) when activity of the primary membrane protein insertase (MisCA [...]
oxaAB protein networkhttps://string-db.org/network/224308.BSU23890Sec-independent factor for membrane protein insertion (YidC/SpoIIIJ family); Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membr [...]
yqjF protein networkhttps://string-db.org/network/224308.BSU23900Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqjE protein networkhttps://string-db.org/network/224308.BSU23910Putative deacylase; Could be a peptidase; Belongs to the peptidase M20A family.
yqjD protein networkhttps://string-db.org/network/224308.BSU23920Putative propionyl-CoA carboxylase beta chain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enz [...]
yqjC protein networkhttps://string-db.org/network/224308.BSU23930Putative methylmalonyl-CoA epimerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belo [...]
yqjB protein networkhttps://string-db.org/network/224308.BSU23940Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqjA protein networkhttps://string-db.org/network/224308.BSU23950Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
artR protein networkhttps://string-db.org/network/224308.BSU23960High affinity arginine ABC transporter (ATP-binding protein); Part of a binding-protein-dependent transport system for arginine. Probably responsible for energy coupling to the transport system.
artQ protein networkhttps://string-db.org/network/224308.BSU23970High affinity arginine ABC transporter (permease); Part of a binding-protein-dependent transport system for arginine. Probably responsible for the translocation of the substrate across the membra [...]
artP protein networkhttps://string-db.org/network/224308.BSU23980High affinity arginine ABC transporter binding lipoprotein; Part of a binding-protein-dependent transport system for arginine.
yqiW protein networkhttps://string-db.org/network/224308.BSU23990Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0403 family.
bmrU protein networkhttps://string-db.org/network/224308.BSU24000Putative lipid kinase BmrU; May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact, is not able to exhibit diacylglycerol kinase activity in vitro.
bmr protein networkhttps://string-db.org/network/224308.BSU24010Multidrug-efflux transporter; Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy s [...]
bmrR protein networkhttps://string-db.org/network/224308.BSU24020Transcriptional regulator (MerR family); Activates transcription of the bmr gene in response to structurally dissimilar drugs. Binds rhodamine as an inducer.
bkdB protein networkhttps://string-db.org/network/224308.BSU24030Branched-chain alpha-keto acid dehydrogenase E2 subunit (lipoamide acyltransferase); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to ac [...]
bkdAB protein networkhttps://string-db.org/network/224308.BSU24040Branched-chain alpha-keto acid dehydrogenase E1 subunit; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contain [...]
bkdAA protein networkhttps://string-db.org/network/224308.BSU24050Branched-chain alpha-keto acid dehydrogenase E1 subunit; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contain [...]
lpdV protein networkhttps://string-db.org/network/224308.BSU24060Branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids [...]
buk protein networkhttps://string-db.org/network/224308.BSU24070Branched-chain fatty-acid kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the acetokinase family.
bcd protein networkhttps://string-db.org/network/224308.BSU24080Branched-chain amino acid dehydrogenase; Catalyzes the reversible deamination of L-leucine to 4- methyl-2-oxopentanoate.
ptb protein networkhttps://string-db.org/network/224308.BSU24090Phosphate butyryl coenzyme A transferase; Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate; Belongs to the phosphate acetyltransferase and butyryltransferase family.
bkdR protein networkhttps://string-db.org/network/224308.BSU24100Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
yqzF protein networkhttps://string-db.org/network/224308.BSU24110Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
mmgF protein networkhttps://string-db.org/network/224308.BSU241202-methylisocitrate lyase; Involved in the methylcitric acid cycle. Catalyzes the cleavage of 2-methylisocitrate to yield pyruvate and succinate.
mmgE protein networkhttps://string-db.org/network/224308.BSU241302-methylcitrate dehydratase; Involved in both the tricarboxylic acid (TCA) and methylcitric acid cycles. Has both 2-methylcitrate dehydratase and citrate dehydratase activities. Catalyzes the deh [...]
mmgD protein networkhttps://string-db.org/network/224308.BSU241402-methylcitrate synthase/citrate synthase III; Involved in both the tricarboxylic acid (TCA) and methylcitric acid cycles. Has both 2-methylcitrate synthase and citrate synthase activities. Catal [...]
mmgC protein networkhttps://string-db.org/network/224308.BSU24150Short chain acyl-CoA dehydrogenase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the acyl-CoA dehydrogenase family [...]
mmgB protein networkhttps://string-db.org/network/224308.BSU241603-hydroxybutyryl-CoA dehydrogenase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the 3-hydroxyacyl-CoA dehydrogena [...]
mmgA protein networkhttps://string-db.org/network/224308.BSU24170Degradative acetoacetyl-CoA thiolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
yqiK protein networkhttps://string-db.org/network/224308.BSU24180Putative glycerophosphodiester phosphodiesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yqiI protein networkhttps://string-db.org/network/224308.BSU24190Putative N-acetylmuramoyl-L-alanine amidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzym [...]
yqiH protein networkhttps://string-db.org/network/224308.BSU24200Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
yqiG protein networkhttps://string-db.org/network/224308.BSU24210Putative NADH-dependent flavin oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enz [...]
spo0A protein networkhttps://string-db.org/network/224308.BSU24220Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritiona [...]
spoIVB protein networkhttps://string-db.org/network/224308.BSU24230Regulatory membrane-associated serine protease; Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activa [...]
recN protein networkhttps://string-db.org/network/224308.BSU24240Factor for double strand breaks DNA repair and genetic recombination; Involved in recombinational repair of damaged DNA. Seems to be the first protein recruited to repair centers, foci that are t [...]
ahrC protein networkhttps://string-db.org/network/224308.BSU24250Transcriptional regulator; Represses the synthesis of biosynthetic enzymes and activates the arginine catabolism. Controls the transcription of the two operons rocABC and rocDEF.
yqxC protein networkhttps://string-db.org/network/224308.BSU24260Putative methyltransferase with RNA binding domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs [...]
dxs protein networkhttps://string-db.org/network/224308.BSU242701-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP) [...]
ispA protein networkhttps://string-db.org/network/224308.BSU24280Geranyltranstransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.
xseB protein networkhttps://string-db.org/network/224308.BSU24290Exodeoxyribonuclease VII (small subunit); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonu [...]
xseA protein networkhttps://string-db.org/network/224308.BSU24300Exodeoxyribonuclease VII (large subunit); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonu [...]
folD protein networkhttps://string-db.org/network/224308.BSU24310Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10 [...]
nusB protein networkhttps://string-db.org/network/224308.BSU24320Transcription termination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence [...]
yqhY protein networkhttps://string-db.org/network/224308.BSU24330Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16014871, 17114254; Belongs to the asp23 family.
accC protein networkhttps://string-db.org/network/224308.BSU24340acetyl-CoA carboxylase subunit (biotin carboxylase subunit); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the [...]
accB protein networkhttps://string-db.org/network/224308.BSU24350acetyl-CoA carboxylase subunit (biotin carboxyl carrier subunit); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation o [...]
spoIIIAH protein networkhttps://string-db.org/network/224308.BSU24360Stage III sporulation ratchet engulfment protein; Involved in forespore engulfment. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. T [...]
spoIIIAG protein networkhttps://string-db.org/network/224308.BSU24370Stage III sporulation engulfment assembly protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
spoIIIAF protein networkhttps://string-db.org/network/224308.BSU24380Stage III sporulation protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
spoIIIAE protein networkhttps://string-db.org/network/224308.BSU24390Stage III sporulation protein; Required during sporulation for activation of sigma factor SpoIIIG/SigG after engulfment is completed in the prespore. Overexpression in the absence of SpoIIIJ is s [...]
spoIIIAD protein networkhttps://string-db.org/network/224308.BSU24400Stage III sporulation protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
spoIIIAC protein networkhttps://string-db.org/network/224308.BSU24410Stage III sporulation protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
spoIIIAB protein networkhttps://string-db.org/network/224308.BSU24420Stage III sporulation protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
spoIIIAA protein networkhttps://string-db.org/network/224308.BSU24430ATP-binding stage III sporulation protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
yqhV protein networkhttps://string-db.org/network/224308.BSU24440Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
efp protein networkhttps://string-db.org/network/224308.BSU24450Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirect [...]
yqhT protein networkhttps://string-db.org/network/224308.BSU24460Putative aminopeptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
aroQ protein networkhttps://string-db.org/network/224308.BSU244703-dehydroquinate dehydratase, type II; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
yqhR protein networkhttps://string-db.org/network/224308.BSU24480Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yqhQ protein networkhttps://string-db.org/network/224308.BSU24490Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqhP protein networkhttps://string-db.org/network/224308.BSU24500Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqhO protein networkhttps://string-db.org/network/224308.BSU24510Conserved hypothetical protein; Probable lipid hydrolase.
mntR protein networkhttps://string-db.org/network/224308.BSU24520Transcriptional regulator (DtxR family); Central regulator of manganese homeostasis that regulates the expression of both manganese uptake and efflux systems. In the presence of high levels of ma [...]
lipM protein networkhttps://string-db.org/network/224308.BSU24530Protein octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protei [...]
yqhL protein networkhttps://string-db.org/network/224308.BSU24540Putative sulfur transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
gcvPB protein networkhttps://string-db.org/network/224308.BSU24550Glycine decarboxylase (subunit 2) (glycine cleavage system protein P); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine throu [...]
gcvPA protein networkhttps://string-db.org/network/224308.BSU24560Glycine decarboxylase (subunit 1) (glycine cleavage system protein P); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine throu [...]
gcvT protein networkhttps://string-db.org/network/224308.BSU24570Aminomethyltransferase (glycine cleavage system protein T); The glycine cleavage system catalyzes the degradation of glycine.
yqhH protein networkhttps://string-db.org/network/224308.BSU24580Putative RNA polymerase-associated helicase protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putati [...]
yqhG protein networkhttps://string-db.org/network/224308.BSU24590Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
sinI protein networkhttps://string-db.org/network/224308.BSU24600Antagonist of SinR; Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE.
sinR protein networkhttps://string-db.org/network/224308.BSU24610Master regulator of biofilm formation; Negative as well as positive regulator of alternate developmental processes that are induced at the end of vegetative growth in response to nutrient depleti [...]
tasA protein networkhttps://string-db.org/network/224308.BSU24620Major biofilm matrix component; TasA is the major protein component of the biofilm extracellular matrix. It forms amyloid fibers that bind cells together in the biofilm. Exhibits an antibacterial [...]
sipW protein networkhttps://string-db.org/network/224308.BSU24630Type I signal peptidase; Required for the cleavage of the signal sequence of TasA and TapA, which are involved in biofilm formation. Belongs to the peptidase S26B family.
tapA protein networkhttps://string-db.org/network/224308.BSU24640Lipoprotein for biofilm formation; Required for biofilm formation. Required for the proper anchoring and polymerization of TasA amyloid fibers at the cell surface. Is also a minor component of Ta [...]
yqzG protein networkhttps://string-db.org/network/224308.BSU24650Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
yqzE protein networkhttps://string-db.org/network/224308.BSU24660Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
comGG protein networkhttps://string-db.org/network/224308.BSU24670Component of the DNA transport platform; Required for transformation and DNA binding.
comGF protein networkhttps://string-db.org/network/224308.BSU24680Component of the DNA transport platform; Required for transformation and DNA binding.
comGE protein networkhttps://string-db.org/network/224308.BSU24690Component of the DNA transport platform; Required for transformation and DNA binding.
comGD protein networkhttps://string-db.org/network/224308.BSU24700Membrane component of the DNA transport platform; Required for transformation and DNA binding.
comGC protein networkhttps://string-db.org/network/224308.BSU24710Pilin-like component of the DNA transport membrane platform; Required for transformation and DNA binding. Belongs to the ComGC family.
comGB protein networkhttps://string-db.org/network/224308.BSU24720Membrane platform component of the DNA transport machinery; Required for transformation and DNA binding. Belongs to the GSP F family.
comGA protein networkhttps://string-db.org/network/224308.BSU24730Membrane associated ATPase for DNA competence; Required for uptake of DNA by competent cells.
yqxL protein networkhttps://string-db.org/network/224308.BSU24740Putative CorA-type Mg(2+) transporter; Mediates influx of magnesium ions. Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) l [...]
yqhB protein networkhttps://string-db.org/network/224308.BSU24750Putative membrane associated protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane com [...]
rsbRD protein networkhttps://string-db.org/network/224308.BSU24760Component of the piezosome (stressosome); One of 4 functionally non-identical RsbR paralogs, it functions in the environmental signaling branch of the general stress response.
mgsR protein networkhttps://string-db.org/network/224308.BSU24770Transcriptional regulator of stress; Regulates transcription of a subregulon within the general stress response. Exerts positive and negative effects in response to ethanol stress.
yqgY protein networkhttps://string-db.org/network/224308.BSU24780Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqgX protein networkhttps://string-db.org/network/224308.BSU24790Putative metal-binding hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yqgW protein networkhttps://string-db.org/network/224308.BSU24800Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqgV protein networkhttps://string-db.org/network/224308.BSU24810Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0045 family.
yqgU protein networkhttps://string-db.org/network/224308.BSU24820Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
yqgT protein networkhttps://string-db.org/network/224308.BSU24830Putative gamma-D-glutamyl-L-diamino acid endopeptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Bel [...]
ltaSC protein networkhttps://string-db.org/network/224308.BSU24840Enzyme responsible for polyglycerolphosphate LTA synthesis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the LTA synthase family.
glcK protein networkhttps://string-db.org/network/224308.BSU24850Glucose kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the ROK (NagC/XylR) family.
yqgQ protein networkhttps://string-db.org/network/224308.BSU24860Putative single strand nucleic acid binding transcription factor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product ty [...]
glpG protein networkhttps://string-db.org/network/224308.BSU24870Membrane endopeptidase; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter.
yqgO protein networkhttps://string-db.org/network/224308.BSU24880Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
folN protein networkhttps://string-db.org/network/224308.BSU248905-formyltetrahydrofolate cyclo-ligase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the 5-formyltetrahydrofolate c [...]
rpmGA protein networkhttps://string-db.org/network/224308.BSU24900Ribosomal protein L33; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; structure.
yqgM protein networkhttps://string-db.org/network/224308.BSU24910Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
yqgL protein networkhttps://string-db.org/network/224308.BSU24920Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqzD protein networkhttps://string-db.org/network/224308.BSU24930Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqzC protein networkhttps://string-db.org/network/224308.BSU24940Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
pstBB protein networkhttps://string-db.org/network/224308.BSU24950Phosphate ABC transporter (ATP-binding protein); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the [...]
pstBA protein networkhttps://string-db.org/network/224308.BSU24960Phosphate ABC transporter (ATP-binding protein); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the [...]
pstA protein networkhttps://string-db.org/network/224308.BSU24970Phosphate ABC transporter (permease); Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similari [...]
pstC protein networkhttps://string-db.org/network/224308.BSU24980Phosphate ABC transporter (permease); Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similari [...]
pstS protein networkhttps://string-db.org/network/224308.BSU24990Phosphate ABC transporter (binding lipoprotein); Part of the ABC transporter complex PstSACB involved in phosphate import.
pbpA protein networkhttps://string-db.org/network/224308.BSU25000Transpeptidase (penicillin-binding protein 2A); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
yqgE protein networkhttps://string-db.org/network/224308.BSU25010Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
sodA protein networkhttps://string-db.org/network/224308.BSU25020Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase [...]
yqgC protein networkhttps://string-db.org/network/224308.BSU25030Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yqgB protein networkhttps://string-db.org/network/224308.BSU25040Factor involved in motility; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type ph: phenotype.
yqgA protein networkhttps://string-db.org/network/224308.BSU25050Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yqfZ protein networkhttps://string-db.org/network/224308.BSU25060Factor involved in motility; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type ph: phenotype.
ispG protein networkhttps://string-db.org/network/224308.BSU250704-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs t [...]
yqfX protein networkhttps://string-db.org/network/224308.BSU25080Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqfW protein networkhttps://string-db.org/network/224308.BSU25090Putative nucleotidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the 5'(3 [...]
zur protein networkhttps://string-db.org/network/224308.BSU25100Transcriptional regulator (Fur family); Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes. Required for the zinc-specific repressi [...]
yqfU protein networkhttps://string-db.org/network/224308.BSU25110Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yqfT protein networkhttps://string-db.org/network/224308.BSU25120Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
nfo protein networkhttps://string-db.org/network/224308.BSU25130Type IV apurinic/apyrimidinic endonuclease; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and [...]
cshB protein networkhttps://string-db.org/network/224308.BSU25140ATP-dependent RNA helicase; DEAD-box RNA helicase that plays a role in 70S ribosome assembly. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at [...]
yqfQ protein networkhttps://string-db.org/network/224308.BSU25150Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ispH protein networkhttps://string-db.org/network/224308.BSU251601-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and di [...]
yqfO protein networkhttps://string-db.org/network/224308.BSU25170Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
trmK protein networkhttps://string-db.org/network/224308.BSU25180tRNA (adenine(22)-N(1))-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 22 (m1A22) in tRNA.
cccA protein networkhttps://string-db.org/network/224308.BSU25190Cytochrome c550; Not essential for growth on minimal or rich media.
sigA protein networkhttps://string-db.org/network/224308.BSU25200RNA polymerase major sigma-43 factor (sigma-A); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma f [...]
dnaG protein networkhttps://string-db.org/network/224308.BSU25210DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
antE protein networkhttps://string-db.org/network/224308.BSU25220Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 9864351.
yqxD protein networkhttps://string-db.org/network/224308.BSU25230Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9387153; Belongs to the UPF0178 family.
yqfL protein networkhttps://string-db.org/network/224308.BSU25240Positive regulator of gluconeogenesis; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylati [...]
ccpN protein networkhttps://string-db.org/network/224308.BSU25250Negative regulator of gluconeogenesis; Transcription repressor that binds to the promoter of gapB and pckA genes, preventing their expression. Acts as a regulator for catabolite repression of glu [...]
glyS protein networkhttps://string-db.org/network/224308.BSU25260glycyl-tRNA synthetase (beta subunit); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
glyQ protein networkhttps://string-db.org/network/224308.BSU25270glycyl-tRNA synthetase (alpha subunit); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
recO protein networkhttps://string-db.org/network/224308.BSU25280DNA double strand break repair and homologous recombination factor; Plays a role in DNA double-stranded break repair. It seems to be involved in an RecBC-independent recombinational process of DN [...]
yqzL protein networkhttps://string-db.org/network/224308.BSU25289Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
era protein networkhttps://string-db.org/network/224308.BSU25290GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in [...]
cdd protein networkhttps://string-db.org/network/224308.BSU25300Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
dgkA protein networkhttps://string-db.org/network/224308.BSU25310Undecaprenol kinase; Catalyzes the phosphorylation of undecaprenol in vitro, which is probably the physiological substrate. Exhibits no detectable activity against other substrates such as monoac [...]
yqfG protein networkhttps://string-db.org/network/224308.BSU25320Putative metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
yqfF protein networkhttps://string-db.org/network/224308.BSU25330Putative membrane associate hydrolase; Probably has phosphodiesterase (PDE) activity against cyclic- di-AMP (c-di-AMP); may be the major c-di-AMP PDE in the cell. In B.subtilis c-di-AMP is a seco [...]
phoH protein networkhttps://string-db.org/network/224308.BSU25340Phosphate starvation-induced protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type ph: phenotype.
yqfD protein networkhttps://string-db.org/network/224308.BSU25350Stage IV sporulation protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type cp: cell process.
yqfC protein networkhttps://string-db.org/network/224308.BSU25360Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12662922.
yqfB protein networkhttps://string-db.org/network/224308.BSU25370Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqfA protein networkhttps://string-db.org/network/224308.BSU25380Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Product type cp: cell process.
yqeZ protein networkhttps://string-db.org/network/224308.BSU25390Putative membrane bound hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yqeY protein networkhttps://string-db.org/network/224308.BSU25400Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
rpsU protein networkhttps://string-db.org/network/224308.BSU25410Ribosomal protein S21; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type s: structure; Belongs to the bacterial ribosomal protein bS21 family [...]
yqeW protein networkhttps://string-db.org/network/224308.BSU25420Putative Na+/anion cotransporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
mtaB protein networkhttps://string-db.org/network/224308.BSU25430tRNA N(6)-threonylcarbamoyladenosine (t(6)A) methylthiotransferase; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonyl [...]
rsmE protein networkhttps://string-db.org/network/224308.BSU25440Methylase of U1498 in 16S rRNA; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) [...]
prmA protein networkhttps://string-db.org/network/224308.BSU25450Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
dnaJ protein networkhttps://string-db.org/network/224308.BSU25460Co-factor of molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, a [...]
dnaK protein networkhttps://string-db.org/network/224308.BSU25470Molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family.
grpE protein networkhttps://string-db.org/network/224308.BSU25480Nucleotide exchange factor for DnaK activity; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with [...]
hrcA protein networkhttps://string-db.org/network/224308.BSU25490Transcriptional regulator of heat-shock genes; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
hemN protein networkhttps://string-db.org/network/224308.BSU25500Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently (By similarity). Binds 1 [ [...]
lepA protein networkhttps://string-db.org/network/224308.BSU25510Ribosomal elongation factor, GTPase; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing [...]
yqxA protein networkhttps://string-db.org/network/224308.BSU25520Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
spoIIP protein networkhttps://string-db.org/network/224308.BSU25530Spore autolysin (stage II sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
gpr protein networkhttps://string-db.org/network/224308.BSU25540Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination.
rpsT protein networkhttps://string-db.org/network/224308.BSU25550Ribosomal protein S20 (BS20); Binds directly to 16S ribosomal RNA; Belongs to the bacterial ribosomal protein bS20 family.
holA protein networkhttps://string-db.org/network/224308.BSU25560DNA polymerase delta subunit; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme.
yqzM protein networkhttps://string-db.org/network/224308.BSU25569Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
comEC protein networkhttps://string-db.org/network/224308.BSU25570DNA channel for uptake in competent cells; The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding; To [...]
comEB protein networkhttps://string-db.org/network/224308.BSU25580Putative enzyme associated to DNA transport (competence); Dispensable for transformability; Belongs to the cytidine and deoxycytidylate deaminase family.
comEA protein networkhttps://string-db.org/network/224308.BSU25590Membrane bound high-affinity DNA-binding receptor; Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding [...]
comER protein networkhttps://string-db.org/network/224308.BSU25600Putative pyrroline-5'-carboxylate reductase; Dispensable for transformability. Not known if it can act as a pyrroline-5-carboxylate reductase.
yqeM protein networkhttps://string-db.org/network/224308.BSU25610Conserved hypothetical protein; May be a S-adenosyl-L-methionine (SAM)-dependent methyltransferase.
rsfS protein networkhttps://string-db.org/network/224308.BSU25620Ribosomal silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S a [...]
yqeK protein networkhttps://string-db.org/network/224308.BSU25630Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
nadD protein networkhttps://string-db.org/network/224308.BSU25640Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD); Belongs to the NadD family.
yqeI protein networkhttps://string-db.org/network/224308.BSU25650Putative RNA-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
aroD protein networkhttps://string-db.org/network/224308.BSU25660Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshi [...]
yqeH protein networkhttps://string-db.org/network/224308.BSU25670GTPase involved in ribosome 30S assembly; Binds GTP and GDP.
yqeG protein networkhttps://string-db.org/network/224308.BSU25680Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
sda protein networkhttps://string-db.org/network/224308.BSU25690Check point factor coupling initiation of sporulation and replication initiation; Mediates a developmental checkpoint inhibiting initiation of sporulation (by preventing phosphorylation of spo0A) [...]
yqeF protein networkhttps://string-db.org/network/224308.BSU25700Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
cwlH protein networkhttps://string-db.org/network/224308.BSU25710N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of [...]
yqeD protein networkhttps://string-db.org/network/224308.BSU25720Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 15855514, 16850406.
yqeC protein networkhttps://string-db.org/network/224308.BSU25730Putative hydroxyacid dehydrogenase; May act as NAD-dependent 6-P-gluconate dehydrogenase.
yqeB protein networkhttps://string-db.org/network/224308.BSU25740Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
nucB protein networkhttps://string-db.org/network/224308.BSU25750Nuclease; Degrades both double-stranded linear and covalently closed circular DNA. Likely to play a scavenging role in order to supply nutrients under starvation conditions; To B.subtilis NucA/Co [...]
spoIVCA protein networkhttps://string-db.org/network/224308.BSU25770RNA polymerase sporulation-specific sigma-K factor precursor (Sigma-27) (N-terminal half); Putative site-specific recombinase having a very important role in sporulation. It probably plays a role [...]
arsC protein networkhttps://string-db.org/network/224308.BSU25780Thioredoxin-coupled arsenate reductase; Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. In vitro, can dephosphorylate para- nitrophenyl phosphate (pNPP). Belongs to the low mol [...]
arsB protein networkhttps://string-db.org/network/224308.BSU25790Arsenite efflux transporter; Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump.
yqcK protein networkhttps://string-db.org/network/224308.BSU25800Putative thiol lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To M.tuberculosis Rv [...]
arsR protein networkhttps://string-db.org/network/224308.BSU25810Transcriptional regulator (ArsR family); Transcriptional repressor for the ars operon.
yqcI protein networkhttps://string-db.org/network/224308.BSU25820Conserved hypothetical protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin; Belongs to the DcsA family.
rapE protein networkhttps://string-db.org/network/224308.BSU25830Response regulator aspartate phosphatase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type r: regulator; Belongs to the RAP family.
phrE protein networkhttps://string-db.org/network/224308.BSU25840Regulator of the activity of phosphatase RapE; Inhibitor of the activity of phosphatase RapE.
yqzI protein networkhttps://string-db.org/network/224308.BSU25850Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
rttG protein networkhttps://string-db.org/network/224308.BSU25860Phage ribonuclease toxin; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 379-531) has RNase activity, and inhibits growth upon expression in E.coli. In vitro R [...]
rttF protein networkhttps://string-db.org/network/224308.BSU25870Antitoxin factor of ribonuclease toxin RttG; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the RNase activity of cognate toxin YqcG, as well as its ability to inhibit [...]
yqxJ protein networkhttps://string-db.org/network/224308.BSU25880Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yqxI protein networkhttps://string-db.org/network/224308.BSU25890Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
cwlA protein networkhttps://string-db.org/network/224308.BSU25900N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of [...]
yqxH protein networkhttps://string-db.org/network/224308.BSU25910Putative holin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yqxG protein networkhttps://string-db.org/network/224308.BSU25920Putative phage-related lytic exoenzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To [...]
yqcE protein networkhttps://string-db.org/network/224308.BSU25930Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdX.
yqcD protein networkhttps://string-db.org/network/224308.BSU25940Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdW.
yqcC protein networkhttps://string-db.org/network/224308.BSU25950Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508; To B.subtilis XkdV.
yqcB protein networkhttps://string-db.org/network/224308.BSU25960Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yqcA protein networkhttps://string-db.org/network/224308.BSU25970Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508; To B.subtilis XkdU.
yqbT protein networkhttps://string-db.org/network/224308.BSU25980Putative phage capsid assembly protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure; [...]
yqbS protein networkhttps://string-db.org/network/224308.BSU25990Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdS.
yqbR protein networkhttps://string-db.org/network/224308.BSU26000Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdR.
yqbQ protein networkhttps://string-db.org/network/224308.BSU26010Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdQ.
yqbP protein networkhttps://string-db.org/network/224308.BSU26020Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqbO protein networkhttps://string-db.org/network/224308.BSU26030Putative lytic transglycosylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To B.subt [...]
txpA protein networkhttps://string-db.org/network/224308.BSU26050Conserved unknown protein (fragment); Toxic component of a type I toxin-antitoxin (TA) system. Overexpression of txpA causes cell lysis; the TxpA protein has been suggested to act on the cell mem [...]
yqbM protein networkhttps://string-db.org/network/224308.BSU26060Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508; To B.subtilis XkdM.
yqbK protein networkhttps://string-db.org/network/224308.BSU26075Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the myoviridae tail sheath protein family.
yqzN protein networkhttps://string-db.org/network/224308.BSU26089Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqbJ protein networkhttps://string-db.org/network/224308.BSU26090Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdJ.
yqbI protein networkhttps://string-db.org/network/224308.BSU26100Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdI.
yqbH protein networkhttps://string-db.org/network/224308.BSU26110Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdH.
yqbG protein networkhttps://string-db.org/network/224308.BSU26120Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqbF protein networkhttps://string-db.org/network/224308.BSU26130Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yqbE protein networkhttps://string-db.org/network/224308.BSU26140Putative phage capsid protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure; To B.sub [...]
yqbD protein networkhttps://string-db.org/network/224308.BSU26150Putative DNA wielding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yqbC protein networkhttps://string-db.org/network/224308.BSU26160Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqbB protein networkhttps://string-db.org/network/224308.BSU26170Putative phage head morphogenesis protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structu [...]
yqbA protein networkhttps://string-db.org/network/224308.BSU26180Putative phage capsid protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure; Belongs [...]
yqaT protein networkhttps://string-db.org/network/224308.BSU26190Putative phage-related terminase large subunit; May function as a terminase; To B.subtilis XtmB and phage SPP1 terminase large subunit.
yqaS protein networkhttps://string-db.org/network/224308.BSU26200Putative phage-related terminase small subunit; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative en [...]
yqaR protein networkhttps://string-db.org/network/224308.BSU26210Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yqaQ protein networkhttps://string-db.org/network/224308.BSU26220Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis pcf and to sigma factors.
yqaP protein networkhttps://string-db.org/network/224308.BSU26230Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqaO protein networkhttps://string-db.org/network/224308.BSU26240Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XtrA.
yqaN protein networkhttps://string-db.org/network/224308.BSU26250Putative Holliday junction resolvase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yqzO protein networkhttps://string-db.org/network/224308.BSU26259Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yqaM protein networkhttps://string-db.org/network/224308.BSU26260Putative replication-related ATPase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To B. [...]
yqaL protein networkhttps://string-db.org/network/224308.BSU26270Putative DNA-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
yqaK protein networkhttps://string-db.org/network/224308.BSU26280Putative DNA recombination protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yqaJ protein networkhttps://string-db.org/network/224308.BSU26290Putative nuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yqaI protein networkhttps://string-db.org/network/224308.BSU26300Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yqaH protein networkhttps://string-db.org/network/224308.BSU26310Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yqaG protein networkhttps://string-db.org/network/224308.BSU26320Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
yqdA protein networkhttps://string-db.org/network/224308.BSU26330Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yqaF protein networkhttps://string-db.org/network/224308.BSU26340Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
yqaE protein networkhttps://string-db.org/network/224308.BSU26350Putative transcriptional regulator (Xre family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative r [...]
yqaD protein networkhttps://string-db.org/network/224308.BSU26360Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yqaC protein networkhttps://string-db.org/network/224308.BSU26370Putative kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yqaB protein networkhttps://string-db.org/network/224308.BSU26380Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yrkS protein networkhttps://string-db.org/network/224308.BSU26400RNA polymerase sporulation-specific sigma-K factor precursor (Sigma-27) (C-terminal fragment); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
psiE protein networkhttps://string-db.org/network/224308.BSU26410Phosphate starvation inducible protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; membrane component.
yrkQ protein networkhttps://string-db.org/network/224308.BSU26420Two-component sensor histidine kinase [YrkP]; Member of the two-component regulatory system YrkQ/YrkP. Probably activates YrkP by phosphorylation.
yrkP protein networkhttps://string-db.org/network/224308.BSU26430Two-component response regulator [YrkQ]; Member of the two-component regulatory system YrkQ/YrkP.
yrkO protein networkhttps://string-db.org/network/224308.BSU26440Putative integral inner membrane protein; Involved in transport.
yrkN protein networkhttps://string-db.org/network/224308.BSU26450Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yrkL protein networkhttps://string-db.org/network/224308.BSU26470Putative NAD(P)H oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the NAD(P)H deh [...]
yrkK protein networkhttps://string-db.org/network/224308.BSU26480Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yrkJ protein networkhttps://string-db.org/network/224308.BSU26490Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yrkI protein networkhttps://string-db.org/network/224308.BSU26500Putative sulfur-carrier protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier; Belongs to the sulfur car [...]
yrkH protein networkhttps://string-db.org/network/224308.BSU26510Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yrkF protein networkhttps://string-db.org/network/224308.BSU26530Putative rhodanese-related sulfur transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enz [...]
yrkE protein networkhttps://string-db.org/network/224308.BSU26540Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yrkD protein networkhttps://string-db.org/network/224308.BSU26550Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
yrkC protein networkhttps://string-db.org/network/224308.BSU26560Hypothetical protein; Evidence 7: Gene remnant.
yrkB protein networkhttps://string-db.org/network/224308.BSU26570Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
bltR protein networkhttps://string-db.org/network/224308.BSU26580Transcriptional regulator; Activates transcription of the blt gene in response to structurally dissimilar drugs.
blt protein networkhttps://string-db.org/network/224308.BSU26590Efflux transporter; Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy source. Cau [...]
bltD protein networkhttps://string-db.org/network/224308.BSU26600Spermine/spermidine acetyltransferase; Acetylates both spermidine and spermine at primary propyl amine moieties, with spermine being the preferred substrate.
yrkA protein networkhttps://string-db.org/network/224308.BSU26610Putative membrane associated protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure.
yrzO protein networkhttps://string-db.org/network/224308.BSU26619Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yrdR protein networkhttps://string-db.org/network/224308.BSU26620Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yrdQ protein networkhttps://string-db.org/network/224308.BSU26630Putative transcriptional regulator (LysR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
yrdP protein networkhttps://string-db.org/network/224308.BSU26640Putative oxidoreductase; Involved in potassium and divalent cation transport. Enhances the transport activity of the cation/potassium transporter CzcD.
czcD protein networkhttps://string-db.org/network/224308.BSU26650Potassium/proton-divalent cation antiporter; Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium [...]
yrdN protein networkhttps://string-db.org/network/224308.BSU26660Putative tautomerase; Putative target of GltR.
gltR protein networkhttps://string-db.org/network/224308.BSU26670Transcriptional regulator (LysR family); Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression; Belongs to the LysR transcriptional regulatory family [...]
yrdK protein networkhttps://string-db.org/network/224308.BSU26680Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
brnQ protein networkhttps://string-db.org/network/224308.BSU26690Low-affinity branched-chain amino acid transporter; Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proton motive force.
azlD protein networkhttps://string-db.org/network/224308.BSU26700Branched-chain amino acid transporter; Involved in branched-chain amino acid transport; Belongs to the AzlD/HI_1737/HP1330 family.
azlC protein networkhttps://string-db.org/network/224308.BSU26710Branched-chain amino acid transporter; Involved in branched-chain amino acid transport; Belongs to the AzlC family.
azlB protein networkhttps://string-db.org/network/224308.BSU26720Transcriptional regulator (Lrp/AsnC family); Transcriptional repressor of the azlBCD operon involved in branched-chain amino acid transport.
yrdF protein networkhttps://string-db.org/network/224308.BSU26730Putative ribonuclease inhibitor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
cypA protein networkhttps://string-db.org/network/224308.BSU26740Cytochrome P450; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
yrdC protein networkhttps://string-db.org/network/224308.BSU26760Hypothetical protein; Evidence 7: Gene remnant; Belongs to the isochorismatase family.
yrdB protein networkhttps://string-db.org/network/224308.BSU26770Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yrdA protein networkhttps://string-db.org/network/224308.BSU26780Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DinB family.
aadK protein networkhttps://string-db.org/network/224308.BSU26790Aminoglycoside 6-adenylyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; To E.faecalis AadE.
yrpB protein networkhttps://string-db.org/network/224308.BSU26800Putative anionic nitroalkane dioxygenase; Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. Acts on propionate 3-nitronate (P3N), t [...]
yrpC protein networkhttps://string-db.org/network/224308.BSU26810Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
yrpD protein networkhttps://string-db.org/network/224308.BSU26820Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; To B.subtilis YncM.
yrpE protein networkhttps://string-db.org/network/224308.BSU26830Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; Belongs to the calycin s [...]
sigZ protein networkhttps://string-db.org/network/224308.BSU26840RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma-Z); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are [...]
yrpG protein networkhttps://string-db.org/network/224308.BSU26850Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the al [...]
yraO protein networkhttps://string-db.org/network/224308.BSU26860Putative citrate transporter; Transports the free citrate anion; Belongs to the CitM (TC 2.A.11) transporter family.
yraN protein networkhttps://string-db.org/network/224308.BSU26870Putative transcriptional regulator (LysR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
yraM protein networkhttps://string-db.org/network/224308.BSU26880Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the PrpF family.
csn protein networkhttps://string-db.org/network/224308.BSU26890Chitosanase; Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
yraL protein networkhttps://string-db.org/network/224308.BSU26900Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yraK protein networkhttps://string-db.org/network/224308.BSU26910Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the AB hydr [...]
yraJ protein networkhttps://string-db.org/network/224308.BSU26920Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YraI.
yraI protein networkhttps://string-db.org/network/224308.BSU26930Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YraJ.
yraH protein networkhttps://string-db.org/network/224308.BSU26940Putative lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glyoxalase [...]
yraG protein networkhttps://string-db.org/network/224308.BSU26950Putative spore coat protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.
yraF protein networkhttps://string-db.org/network/224308.BSU26960Putative spore coat protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.
adhB protein networkhttps://string-db.org/network/224308.BSU26970Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the zinc-containing alc [...]
yraE protein networkhttps://string-db.org/network/224308.BSU26980Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yraD protein networkhttps://string-db.org/network/224308.BSU26990Putative spore coat protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.
yraB protein networkhttps://string-db.org/network/224308.BSU27000Putative transcriptional regulator (MerR family); Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own [...]
yrzP protein networkhttps://string-db.org/network/224308.BSU27009Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17962296.
adhA protein networkhttps://string-db.org/network/224308.BSU27010Putative dehydrogenase; Functions in the protection against aldehyde-stress. Belongs to the zinc-containing alcohol dehydrogenase family.
yraA protein networkhttps://string-db.org/network/224308.BSU27020General stress protein; Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins.
sacC protein networkhttps://string-db.org/network/224308.BSU27030Levanase; Exo-fructosidase that can hydrolyze both levan and inulin, leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose, but not melezit [...]
levG protein networkhttps://string-db.org/network/224308.BSU27040Phosphotransferase system (PTS) fructose-specific enzyme IID component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, cat [...]
levF protein networkhttps://string-db.org/network/224308.BSU27050Phosphotransferase system (PTS) fructose-specific enzyme IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, cat [...]
levE protein networkhttps://string-db.org/network/224308.BSU27060Phosphotransferase system (PTS) fructose-specific enzyme IIB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport syste [...]
levD protein networkhttps://string-db.org/network/224308.BSU27070Phosphotransferase system (PTS) fructose-specific enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system [...]
levR protein networkhttps://string-db.org/network/224308.BSU27080Transcriptional regulator (NifA/NtrC family); Involved in positive regulation of the levanase operon which comprises the levDEFG genes for a fructose PTS system, and sacA for levanase.
aapA protein networkhttps://string-db.org/network/224308.BSU27090d-Serine/d-alanine/glycine permease; Probable amino-acid or metabolite transport protein; Belongs to the amino acid-polyamine-organocation (APC) superfamily.
yrhP protein networkhttps://string-db.org/network/224308.BSU27100Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yrhO protein networkhttps://string-db.org/network/224308.BSU27110Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
sigV protein networkhttps://string-db.org/network/224308.BSU27120RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are [...]
rsiV protein networkhttps://string-db.org/network/224308.BSU27130anti-sigma(V) factor; Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction.
oatA protein networkhttps://string-db.org/network/224308.BSU27140Peptidoglycan O-acetyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme.
yrhK protein networkhttps://string-db.org/network/224308.BSU27150Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
cypB protein networkhttps://string-db.org/network/224308.BSU27160Cytochrome P450 CYP102A3; Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of a range of medium to long-chain fatty acids, with a preference for long-chain unsaturated and branche [...]
bscR protein networkhttps://string-db.org/network/224308.BSU27170Transcriptional regulator for cypB; Negatively regulates the transcription of the fatR-cypB operon. Is displaced from its operator by a range of fatty acids such as oleate, linoleate and phytanat [...]
yrhH protein networkhttps://string-db.org/network/224308.BSU27180Putative methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yrzI protein networkhttps://string-db.org/network/224308.BSU27190Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yrhG protein networkhttps://string-db.org/network/224308.BSU27200Putative formate/nitrite transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yrhF protein networkhttps://string-db.org/network/224308.BSU27210Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yrhE protein networkhttps://string-db.org/network/224308.BSU27220Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; In the C-t [...]
yrhD protein networkhttps://string-db.org/network/224308.BSU27230Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10913079; To A.fulgidus AF1717.
yrhC protein networkhttps://string-db.org/network/224308.BSU27240Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17056751.
mccB protein networkhttps://string-db.org/network/224308.BSU27250Cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway; Catalyzes the conversion of cystathionine to cysteine, and homocysteine to sulfide.
mccA protein networkhttps://string-db.org/network/224308.BSU27260Cystathionine beta-synthase for the reverse transsulfuration pathway; Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine.
mtnN protein networkhttps://string-db.org/network/224308.BSU27270Methylthioadenosine / S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) [...]
yrrT protein networkhttps://string-db.org/network/224308.BSU27280Putative AdoMet-dependent methyltransferase; Could be a S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the methyltransferase superfamily. YrrT family.
yrzA protein networkhttps://string-db.org/network/224308.BSU27290Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yrrS protein networkhttps://string-db.org/network/224308.BSU27300Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 14679248.
pbpI protein networkhttps://string-db.org/network/224308.BSU27310Penicillin-binding protein PBP4B; Penicillin-binding protein with an unknown catalytic activity. Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactama [...]
greA protein networkhttps://string-db.org/network/224308.BSU27320Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a [...]
udk protein networkhttps://string-db.org/network/224308.BSU27330Uridine kinase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme.
yrrO protein networkhttps://string-db.org/network/224308.BSU27340Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the peptida [...]
yrrN protein networkhttps://string-db.org/network/224308.BSU27350Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the peptida [...]
yrrM protein networkhttps://string-db.org/network/224308.BSU27360Putative acyl-CoA O-methyltransferase; Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
yrrL protein networkhttps://string-db.org/network/224308.BSU27370Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG [...]
yrzB protein networkhttps://string-db.org/network/224308.BSU27380Putative anti-sigma factor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator; Belongs to [...]
yrrK protein networkhttps://string-db.org/network/224308.BSU27390Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
yrzL protein networkhttps://string-db.org/network/224308.BSU27400Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0297 family.
alaS protein networkhttps://string-db.org/network/224308.BSU27410alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
yrrI protein networkhttps://string-db.org/network/224308.BSU27420Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
glnQ protein networkhttps://string-db.org/network/224308.BSU27430Glutamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for energy coupling to the transport system (By [...]
glnH protein networkhttps://string-db.org/network/224308.BSU27440Glutamine ABC transporter (glutamine-binding lipoprotein); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport; Belongs to the bacterial solute-binding protein 3 family.
glnM protein networkhttps://string-db.org/network/224308.BSU27450Glutamine ABC transporter (permease); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane [...]
glnP protein networkhttps://string-db.org/network/224308.BSU27460Glutamine ABC transporter (permease); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane [...]
yrzQ protein networkhttps://string-db.org/network/224308.BSU27468Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yrzR protein networkhttps://string-db.org/network/224308.BSU27469Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yrrD protein networkhttps://string-db.org/network/224308.BSU27470Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
recD protein networkhttps://string-db.org/network/224308.BSU27480Exodeoxyribonuclease V alpha chain; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for he [...]
yrrB protein networkhttps://string-db.org/network/224308.BSU27490Putative tetratricopeptide repeat family protein; Could be an interacting mediator in the complex formation among RNA sulfuration components, RNA processing components, and aminoacyl-tRNA synthet [...]
mnmA protein networkhttps://string-db.org/network/224308.BSU27500tRNA 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
iscSA protein networkhttps://string-db.org/network/224308.BSU27510Cysteine desulfurase involved in tRNA thiolation; Catalyzes the removal of elemental sulfur from cysteine to produce alanine.
cymR protein networkhttps://string-db.org/network/224308.BSU27520Transcriptional regulator of cysteine biosynthesis; Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cys [...]
rarA protein networkhttps://string-db.org/network/224308.BSU27530DNA-dependent ATPase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfami [...]
yrvM protein networkhttps://string-db.org/network/224308.BSU27540Putative factor involved in sulfur-containing coenzyme synthesis; Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) [...]
aspS protein networkhttps://string-db.org/network/224308.BSU27550aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: [...]
hisS protein networkhttps://string-db.org/network/224308.BSU27560histidyl-tRNA synthetase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
yrzK protein networkhttps://string-db.org/network/224308.BSU27570Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yrvJ protein networkhttps://string-db.org/network/224308.BSU27580Putative N-acetylmuramoyl-L-alanine amidase, family 3; Probably involved in cell-wall metabolism.
dtd protein networkhttps://string-db.org/network/224308.BSU27590D-Tyr-tRNATyr deacylase; A non-functional D-aminoacyl-tRNA deacylase.
rsh protein networkhttps://string-db.org/network/224308.BSU27600GTP pyrophosphokinase (RelA/SpoT); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in resp [...]
apt protein networkhttps://string-db.org/network/224308.BSU27610Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
recJ protein networkhttps://string-db.org/network/224308.BSU27620Putative single-strand DNA-specific exonuclease; Putative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or Aa [...]
yrvD protein networkhttps://string-db.org/network/224308.BSU27630Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yrvC protein networkhttps://string-db.org/network/224308.BSU27640Putative potassium transport accessory component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
secDF protein networkhttps://string-db.org/network/224308.BSU27650Protein-export membrane protein; Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the [...]
comN protein networkhttps://string-db.org/network/224308.BSU27660Post-transcriptional regulator; Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites.
spoVB protein networkhttps://string-db.org/network/224308.BSU27670Putative putative translocase with flippase function for teichoic acid synthesis; Involved, directly or indirectly, in spore cortex biosynthesis. Affects only indirectly the expression of late sp [...]
yrbG protein networkhttps://string-db.org/network/224308.BSU27680Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yrzE protein networkhttps://string-db.org/network/224308.BSU27690Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yrbF protein networkhttps://string-db.org/network/224308.BSU27700Component of the preprotein translocase; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into [...]
tgt protein networkhttps://string-db.org/network/224308.BSU27710tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in t [...]
queA protein networkhttps://string-db.org/network/224308.BSU27720S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ [...]
yrzS protein networkhttps://string-db.org/network/224308.BSU27729Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ruvB protein networkhttps://string-db.org/network/224308.BSU27730Holliday junction DNA helicase, ATP-dependent component; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that i [...]
ruvA protein networkhttps://string-db.org/network/224308.BSU27740Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exch [...]
bofC protein networkhttps://string-db.org/network/224308.BSU27750Bypass of forespore C, intercompartmental signaling factor; Inhibits the SpoIVB zymogen from undergoing autocatalytic activation by an unknown mechanism, and in this way plays a role in the sigma [...]
csbX protein networkhttps://string-db.org/network/224308.BSU27760Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the maj [...]
yrbE protein networkhttps://string-db.org/network/224308.BSU27770Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the Gf [...]
yrzF protein networkhttps://string-db.org/network/224308.BSU27785Putative serine/threonine-protein kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; [...]
BSU27786 protein networkhttps://string-db.org/network/224308.BSU27786Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yrzH protein networkhttps://string-db.org/network/224308.BSU27800Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yrzT protein networkhttps://string-db.org/network/224308.BSU27809Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yrbD protein networkhttps://string-db.org/network/224308.BSU27810Sodium/proton-dependent alanine transporter; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; transporter.
yrbC protein networkhttps://string-db.org/network/224308.BSU27820Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
coxA protein networkhttps://string-db.org/network/224308.BSU27830Spore cortex protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.
safA protein networkhttps://string-db.org/network/224308.BSU27840Morphogenetic protein associated with SpoVID; Probably involved in the assembly of some coat protein components implicated in both lysozyme resistance and germination. Could be required for the a [...]
nadA protein networkhttps://string-db.org/network/224308.BSU27850Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
nadC protein networkhttps://string-db.org/network/224308.BSU27860Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA).
nadB protein networkhttps://string-db.org/network/224308.BSU27870L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
nifS protein networkhttps://string-db.org/network/224308.BSU27880Putative desulfurase involved in iron-sulfur clusters for NAD biosynthesis; Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). Seems to be required for NA [...]
niaR protein networkhttps://string-db.org/network/224308.BSU27890Transcriptional repressor of de novo NAD biosynthesis; In the presence of nicotinic acid represses transcription of the nadBCA and nifS-nadR operons. Also binds to DNA upstream of the niaP gene, [...]
pheA protein networkhttps://string-db.org/network/224308.BSU27900Prephenate dehydratase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
yszB protein networkhttps://string-db.org/network/224308.BSU27910Conserved hypothetical protein containing an ACT domain; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 2537815; Belongs to the UPF0735 family.
obg protein networkhttps://string-db.org/network/224308.BSU27920GTPase involved in cell partioning and DNA repair; Necessary for the transition from vegetative growth to stage 0 or stage II of sporulation, but sporulation subsequent to these stages is unaffec [...]
spo0B protein networkhttps://string-db.org/network/224308.BSU27930Sporulation initiation phosphotransferase; Key element in the phosphorelay regulating sporulation initiation. Acts on spo0A. Mediates reversible phosphoryl transfer from spo0F to spo0A.
rpmA protein networkhttps://string-db.org/network/224308.BSU27940Ribosomal protein L27 (BL24); Plays a role in sporulation at high temperatures.
ysxB protein networkhttps://string-db.org/network/224308.BSU27950Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11567142; To M.genitalium MG233.
rplU protein networkhttps://string-db.org/network/224308.BSU27960Ribosomal protein L21 (BL20); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
spoIVFB protein networkhttps://string-db.org/network/224308.BSU27970Membrane metalloprotease; Implicated in the coupling of mother cell to forespore gene expression. Required for spore formation. Processes the pro-sigma K factor.
spoIVFA protein networkhttps://string-db.org/network/224308.BSU27980Regulator of SpoIVFB (stage IV sporulation); Implicated in the coupling of mother cell to forespore gene expression. Required for spore formation at 37 degrees Celsius, but not at 30 degrees Cels [...]
minD protein networkhttps://string-db.org/network/224308.BSU27990ATPase activator of MinC; ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation [...]
minC protein networkhttps://string-db.org/network/224308.BSU28000Cell-division regulator (septum placement); Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filamen [...]
mreD protein networkhttps://string-db.org/network/224308.BSU28010Cell-shape determining protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins (By similarity).
mreC protein networkhttps://string-db.org/network/224308.BSU28020Cell-shape determining protein; Involved in formation and maintenance of cell shape. Required for the formation of proper helical filaments of MreB and for cell wall synthesis in the cylindrical [...]
mreB protein networkhttps://string-db.org/network/224308.BSU28030Cell-shape determining protein; Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus c [...]
radC protein networkhttps://string-db.org/network/224308.BSU28040Putative DNA repair protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
maf protein networkhttps://string-db.org/network/224308.BSU28050Septum formation DNA-binding protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. Can also hydrolyze CTP and the modified nucleotides pseudo- UTP, 5-methyl-CTP (m(5)CTP) [...]
spoIIB protein networkhttps://string-db.org/network/224308.BSU28060Stage II sporulation protein B; Involved in endospore development.
comC protein networkhttps://string-db.org/network/224308.BSU28070Membrane protease and transmethylase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue; Belongs to the peptidase A24 family.
folC protein networkhttps://string-db.org/network/224308.BSU28080Folyl-polyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate [...]
valS protein networkhttps://string-db.org/network/224308.BSU28090valyl-tRNA synthetase; As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that h [...]
ysxE protein networkhttps://string-db.org/network/224308.BSU28100Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
spoVID protein networkhttps://string-db.org/network/224308.BSU28110Morphogenetic spore protein (stage VI sporulation); Required for assembly of a normal spore coat. May be a component of the innermost layer of the spore coat that aids in its adherence to the pre [...]
hemL protein networkhttps://string-db.org/network/224308.BSU28120Glutamate-1-semialdehyde 2,1-aminotransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
hemB protein networkhttps://string-db.org/network/224308.BSU28130Delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a dis [...]
hemD protein networkhttps://string-db.org/network/224308.BSU28140Uroporphyrinogen III cosynthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. Belongs to the uroporphyrinogen-III synthase famil [...]
hemC protein networkhttps://string-db.org/network/224308.BSU28150Porphobilinogen deaminase (hydroxymethylbilane synthase); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HM [...]
hemX protein networkhttps://string-db.org/network/224308.BSU28160Negative effector of the concentration of glutamyl-tRNA reductase HemA; Required for HemL synthesis; To M.leprae U1620K.
hemA protein networkhttps://string-db.org/network/224308.BSU28170glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
ysxD protein networkhttps://string-db.org/network/224308.BSU28180Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ysxC protein networkhttps://string-db.org/network/224308.BSU28190GTPase involved in ribosome 50S subunit assembly; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase [...]
lonA protein networkhttps://string-db.org/network/224308.BSU28200Class III heat-shock ATP-dependent LonA protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory [...]
lonB protein networkhttps://string-db.org/network/224308.BSU28210LonB ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required fo [...]
clpX protein networkhttps://string-db.org/network/224308.BSU28220Protein unfolding ATPase required for presentation of proteins to proteases; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform c [...]
tig protein networkhttps://string-db.org/network/224308.BSU28230Prolyl isomerase (trigger factor); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans i [...]
ysoA protein networkhttps://string-db.org/network/224308.BSU28240Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
leuD protein networkhttps://string-db.org/network/224308.BSU282503-isopropylmalate dehydratase (small subunit); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. L [...]
leuC protein networkhttps://string-db.org/network/224308.BSU282603-isopropylmalate dehydratase (large subunit); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate; Belongs to the aconitase/IPM [...]
leuB protein networkhttps://string-db.org/network/224308.BSU282703-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
leuA protein networkhttps://string-db.org/network/224308.BSU282802-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isoprop [...]
ilvC protein networkhttps://string-db.org/network/224308.BSU28290Acetohydroxy-acid isomeroreductase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) [...]
ilvH protein networkhttps://string-db.org/network/224308.BSU28300Acetolactate synthase (acetohydroxy-acid synthase) (small subunit); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to t [...]
ilvB protein networkhttps://string-db.org/network/224308.BSU28310Acetolactate synthase (acetohydroxy-acid synthase) (large subunit); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
ysnD protein networkhttps://string-db.org/network/224308.BSU28320Inner spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
ysnE protein networkhttps://string-db.org/network/224308.BSU28330Putative indole acetic acid acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enz [...]
ysnF protein networkhttps://string-db.org/network/224308.BSU28340Putative stress response protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; phenotype.
ysnB protein networkhttps://string-db.org/network/224308.BSU28350Phosphoesterase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; Belongs to the metallophosphoesterase superfamily. YfcE family.
rdgB protein networkhttps://string-db.org/network/224308.BSU28360Inosine/xanthosine triphosphate pyrophosphatase (subunit A); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference f [...]
rph protein networkhttps://string-db.org/network/224308.BSU28370Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucl [...]
gerM protein networkhttps://string-db.org/network/224308.BSU28380Germination (cortex hydrolysis) and sporulation (stage II, multiple polar septa) lytic enzyme; Unknown. Affects both sporulation and germination.
racE protein networkhttps://string-db.org/network/224308.BSU28390Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
ysmB protein networkhttps://string-db.org/network/224308.BSU28400Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
gerE protein networkhttps://string-db.org/network/224308.BSU28410Transcriptional regulator; Involved in the regulation of spore formation. Directs the transcription of several genes that encode structural components of the protein coat that encases the mature [...]
ysmA protein networkhttps://string-db.org/network/224308.BSU28420Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
sdhB protein networkhttps://string-db.org/network/224308.BSU28430Succinate dehydrogenase (iron-sulfur protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the succinate dehydrogenase/fumarate red [...]
sdhA protein networkhttps://string-db.org/network/224308.BSU28440Succinate dehydrogenase (flavoprotein subunit); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.
sdhC protein networkhttps://string-db.org/network/224308.BSU28450Succinate dehydrogenase (cytochrome b558 subunit); Di-heme cytochrome of the succinate dehydrogenase complex.
yslB protein networkhttps://string-db.org/network/224308.BSU28460Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
lysC protein networkhttps://string-db.org/network/224308.BSU28470Aspartokinase II alpha subunit (aa 1->408) and beta subunit (aa 246->408); Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which [...]
uvrC protein networkhttps://string-db.org/network/224308.BSU28490Excinuclease ABC (subunit C); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is respons [...]
trxA protein networkhttps://string-db.org/network/224308.BSU28500Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
xsa protein networkhttps://string-db.org/network/224308.BSU28510alpha-L-arabinofuranosidase; Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-L-arabinofura [...]
etfA protein networkhttps://string-db.org/network/224308.BSU28520Electron transfer flavoprotein (alpha subunit); The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respirat [...]
etfB protein networkhttps://string-db.org/network/224308.BSU28530Electron transfer flavoprotein (beta subunit); The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respirato [...]
fadB protein networkhttps://string-db.org/network/224308.BSU28540enoyl-CoA hydratase; Involved in the degradation of long-chain fatty acids.
fadR protein networkhttps://string-db.org/network/224308.BSU28550Transcriptional regulator of fatty acids degradation (TetR/AcrR family); Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport an [...]
lcfA protein networkhttps://string-db.org/network/224308.BSU28560Long chain acyl-CoA ligase (degradative); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
yshE protein networkhttps://string-db.org/network/224308.BSU28570Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
mutSB protein networkhttps://string-db.org/network/224308.BSU28580Putative DNA mismatch repair enzyme; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; [...]
polX protein networkhttps://string-db.org/network/224308.BSU28590DNA polymerase/3'-5' exonuclease X; Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate gr [...]
yshB protein networkhttps://string-db.org/network/224308.BSU28600Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane compo [...]
yshA protein networkhttps://string-db.org/network/224308.BSU28610Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the forma [...]
rnhC protein networkhttps://string-db.org/network/224308.BSU28620Ribonuclease HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. RnhC subfamily.
pheT protein networkhttps://string-db.org/network/224308.BSU28630phenylalanyl-tRNA synthetase (beta subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subu [...]
pheS protein networkhttps://string-db.org/network/224308.BSU28640phenylalanyl-tRNA synthetase (alpha subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-II aminoacyl-tRNA synthetase fa [...]
ysgA protein networkhttps://string-db.org/network/224308.BSU28650Putative RNA methylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the cla [...]
sspI protein networkhttps://string-db.org/network/224308.BSU28660Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the SspI family.
ysfB protein networkhttps://string-db.org/network/224308.BSU28670Putative regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator; Belongs to the CdaR [...]
glcD protein networkhttps://string-db.org/network/224308.BSU28680Glycolate oxidase subunit; Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is also able to oxidize D-lactate ((R)- lactate). Does not link directly to O(2), and 2, [...]
glcF protein networkhttps://string-db.org/network/224308.BSU28690Glycolate oxidase iron-sulfur subunit; Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is also able to oxidize D-lactate ((R)- lactate). Does not link directly to [...]
ysfE protein networkhttps://string-db.org/network/224308.BSU28700Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
cstA protein networkhttps://string-db.org/network/224308.BSU28710Carbon starvation-induced membrane protein; Involved in peptide utilization. Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
abfA protein networkhttps://string-db.org/network/224308.BSU28720alpha-L-arabinofuranosidase; Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-(1->5)-arabin [...]
araQ protein networkhttps://string-db.org/network/224308.BSU28730Arabinose/arabinan permease; Part of the binding-protein-dependent transport system for L- arabinose. Probably responsible for the translocation of the substrate across the membrane.
araP protein networkhttps://string-db.org/network/224308.BSU28740Arabinose/arabinan permease; Part of the binding-protein-dependent transport system for L- arabinose. Probably responsible for the translocation of the substrate across the membrane.
araN protein networkhttps://string-db.org/network/224308.BSU28750Sugar-binding lipoprotein; Part of the binding-protein-dependent transport system for L- arabinose.
araM protein networkhttps://string-db.org/network/224308.BSU28760Glycerol-1-phosphate dehydrogenase [NAD(P)+]; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus gen [...]
araL protein networkhttps://string-db.org/network/224308.BSU28770Glycolytic and pentose phosphate intermediates phosphatase; Catalyzes the dephosphorylation of C5 and C6 carbon sugars in vitro. Catalyzes the dephosphorylation of 3'-AMP and phosphoserine in vit [...]
araD protein networkhttps://string-db.org/network/224308.BSU28780L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroald [...]
araB protein networkhttps://string-db.org/network/224308.BSU28790L-ribulokinase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the ribulokinase family.
araA protein networkhttps://string-db.org/network/224308.BSU28800L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.
abnA protein networkhttps://string-db.org/network/224308.BSU28810Arabinan-endo 1,5-alpha-L-arabinase; Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5 [...]
ysdC protein networkhttps://string-db.org/network/224308.BSU28820Putative aminopeptidase ysdC; Putative aminopeptidase.
ysdB protein networkhttps://string-db.org/network/224308.BSU28830Conserved hypothetical protein; May mediate a negative feedback loop that down-regulates the expression of the sigma-W regulon following the activation of sigma-W in response to conditions of cel [...]
ysdA protein networkhttps://string-db.org/network/224308.BSU28840Putative membrane component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
rplT protein networkhttps://string-db.org/network/224308.BSU28850Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing function [...]
rpmI protein networkhttps://string-db.org/network/224308.BSU28860Ribosomal protein L35; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; structure.
infC protein networkhttps://string-db.org/network/224308.BSU28870Initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the av [...]
yscB protein networkhttps://string-db.org/network/224308.BSU28890Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein.
lrgB protein networkhttps://string-db.org/network/224308.BSU28900Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affe [...]
lrgA protein networkhttps://string-db.org/network/224308.BSU28910Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affe [...]
lytT protein networkhttps://string-db.org/network/224308.BSU28920Two-component response regulator [LytS]; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism.
lytS protein networkhttps://string-db.org/network/224308.BSU28930Two-component sensor histidine kinase [LytT]; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism.
ysaA protein networkhttps://string-db.org/network/224308.BSU28940Putative phosphatase; Catalyzes the last step of the phosphorylated serine biosynthetic pathway, i.e. dephosphorylation of O-phospho-L-serine to form L-serine. To a lesser extent, is also able to [...]
thrS protein networkhttps://string-db.org/network/224308.BSU28950threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor en [...]
ytxC protein networkhttps://string-db.org/network/224308.BSU28960Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ytxB protein networkhttps://string-db.org/network/224308.BSU28970Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
dnaI protein networkhttps://string-db.org/network/224308.BSU28980Helicase loader; Probably involved in DNA replication.
dnaB protein networkhttps://string-db.org/network/224308.BSU28990Helicase loading protein; Probable component of primosome involved in the initiation of DNA replication. It is essential for both replication initiation and membrane attachment of the origin regi [...]
nrdR protein networkhttps://string-db.org/network/224308.BSU29000Negative regulator of transcription of ribonucleotide reductase nrd genes and operons; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to [...]
speD protein networkhttps://string-db.org/network/224308.BSU29010S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamin [...]
gapB protein networkhttps://string-db.org/network/224308.BSU29020Glyceraldehyde-3-phosphate dehydrogenase; Involved in the gluconeogenesis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3- bisphosphoglycerate (BPG) using the [...]
ytcD protein networkhttps://string-db.org/network/224308.BSU29030Putative transcriptional regulator (MarD family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
ytbD protein networkhttps://string-db.org/network/224308.BSU29040Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ytbE protein networkhttps://string-db.org/network/224308.BSU29050Putative aldo/keto reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
coaE protein networkhttps://string-db.org/network/224308.BSU29060Dephosphocoenzyme A kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
ytaF protein networkhttps://string-db.org/network/224308.BSU29070Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
mutM protein networkhttps://string-db.org/network/224308.BSU29080formamidopyrimidine-DNA glycosidase; Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo- dGTP) from DNA and the nucleotide [...]
polA protein networkhttps://string-db.org/network/224308.BSU29090DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
phoR protein networkhttps://string-db.org/network/224308.BSU29100Two-component sensor histidine kinase; Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated pr [...]
phoP protein networkhttps://string-db.org/network/224308.BSU29110Two-component response regulator; Member of the two-component regulatory system PhoP/PhoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase.
mdh protein networkhttps://string-db.org/network/224308.BSU29120Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
icd protein networkhttps://string-db.org/network/224308.BSU29130Isocitrate dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
citZ protein networkhttps://string-db.org/network/224308.BSU29140Citrate synthase II; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect; Belongs to the citrate [...]
ytwI protein networkhttps://string-db.org/network/224308.BSU29150Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane compo [...]
ytvI protein networkhttps://string-db.org/network/224308.BSU29160Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ytzA protein networkhttps://string-db.org/network/224308.BSU29170Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
pyk protein networkhttps://string-db.org/network/224308.BSU29180Pyruvate kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; In the C-terminal section; belongs to the PEP-utilizing enzyme family.
pfkA protein networkhttps://string-db.org/network/224308.BSU291906-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase typ [...]
accA protein networkhttps://string-db.org/network/224308.BSU29200acetyl-CoA carboxylase (carboxyltransferase alpha subunit); Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its ca [...]
accD protein networkhttps://string-db.org/network/224308.BSU29210acetyl-CoA carboxylase (carboxyltransferase beta subunit); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carri [...]
ytsJ protein networkhttps://string-db.org/network/224308.BSU29220NADP-dependent malic enzyme (conversion of malate into pyruvate); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
dnaE protein networkhttps://string-db.org/network/224308.BSU29230DNA polymerase III (alpha subunit); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' ex [...]
ytrH protein networkhttps://string-db.org/network/224308.BSU29239Membrane protein involved in a sporulation process; Involved in sporulation. May contribute to cortex formation or stability.
ytrI protein networkhttps://string-db.org/network/224308.BSU29240Protein involved in sporulation; Involved in sporulation.
ytzJ protein networkhttps://string-db.org/network/224308.BSU29249Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
nrnA protein networkhttps://string-db.org/network/224308.BSU29250Oligoribonuclease (nanoRNAse), 3',5'-bisphosphate nucleotidase; Bifunctional enzyme which has both oligoribonuclease and pAp- phosphatase activities. Degrades RNA and DNA oligonucleotides with a [...]
ytpI protein networkhttps://string-db.org/network/224308.BSU29260Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ytoI protein networkhttps://string-db.org/network/224308.BSU29270Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ytnM protein networkhttps://string-db.org/network/224308.BSU29280Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ytnL protein networkhttps://string-db.org/network/224308.BSU29290Putative aminohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the pe [...]
rbfK protein networkhttps://string-db.org/network/224308.BSU29300RNA-binding cryptic riboflavin kinase regulatory protein; May be directly involved in the regulation of the rib genes. C-terminal part of RibR specifically binds to RFN of the rib leader of the r [...]
ytnJ protein networkhttps://string-db.org/network/224308.BSU29310Putative monooxygenase; May play a role in methionine degradation. May play a role in a sulfur salvage pathway.
ytnI protein networkhttps://string-db.org/network/224308.BSU29320Putative redoxin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glutaredo [...]
ytmO protein networkhttps://string-db.org/network/224308.BSU29330Putative monooxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To bacterial alkan [...]
tcyN protein networkhttps://string-db.org/network/224308.BSU29340Sulfur-containing amino-acid ABC transporter (ATP-binding protein); Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Responsible for energy coupling to the transport sy [...]
tcyM protein networkhttps://string-db.org/network/224308.BSU29350Sulfur-containing amino acid ABC transporter (permease); Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Probably responsible for the translocation of the substrate ac [...]
tcyL protein networkhttps://string-db.org/network/224308.BSU29360Sulfur-containing amino acid ABC transporter (permease); Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Probably responsible for the translocation of the substrate ac [...]
tcyK protein networkhttps://string-db.org/network/224308.BSU29370Sulfur-containing amino acid ABC transporter binding lipoprotein; Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Is also involved in cystathionine, djenkolate, and S- [...]
tcyJ protein networkhttps://string-db.org/network/224308.BSU29380Sulfur containing amino acid ABC transporter binding lipoprotein; Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Is also involved in cystathionine, djenkolate, and S- [...]
ytmI protein networkhttps://string-db.org/network/224308.BSU29390Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
ytlI protein networkhttps://string-db.org/network/224308.BSU29400Transcriptional regulator (LysR family); Positively regulates the expression of ytmI operon in response to the availability of sulfur sources.
ytkL protein networkhttps://string-db.org/network/224308.BSU29410Putative metal-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belong [...]
ytkK protein networkhttps://string-db.org/network/224308.BSU29420Putative 3-oxoacyl-acyl-carrier protein reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative [...]
ytzD protein networkhttps://string-db.org/network/224308.BSU29430Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 11423008.
argH protein networkhttps://string-db.org/network/224308.BSU29440Argininosuccinate lyase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
argG protein networkhttps://string-db.org/network/224308.BSU29450Argininosuccinate synthase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
moaB protein networkhttps://string-db.org/network/224308.BSU29460Molybdopterin GTP-binding precursor Z biosynthesis component; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
ackA protein networkhttps://string-db.org/network/224308.BSU29470Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Appears to favor the formation of acetate. Involved in the secretion of e [...]
ytxK protein networkhttps://string-db.org/network/224308.BSU29480Putative nucleic acid methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; T [...]
tpx protein networkhttps://string-db.org/network/224308.BSU29490Putative peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection [...]
ytfJ protein networkhttps://string-db.org/network/224308.BSU29500Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ytfI protein networkhttps://string-db.org/network/224308.BSU29510Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yteJ protein networkhttps://string-db.org/network/224308.BSU29520Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
sppA protein networkhttps://string-db.org/network/224308.BSU29530Signal peptide peptidase; Digestion of cleaved signal peptides (By similarity). Required for efficient processing of precursors under conditions of hyper-secretion. Has a preference for leucine-r [...]
ppnKB protein networkhttps://string-db.org/network/224308.BSU29540Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosph [...]
ytcJ protein networkhttps://string-db.org/network/224308.BSU29550Putative metal-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belong [...]
ytcI protein networkhttps://string-db.org/network/224308.BSU29560Putative acyl-coenzyme A synthetase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belon [...]
sspA protein networkhttps://string-db.org/network/224308.BSU29570Small acid-soluble spore protein (alpha-type SASP); SASP are bound to spore DNA. They are double-stranded DNA- binding proteins that cause DNA to change to an a-like conformation. They protect th [...]
thiI protein networkhttps://string-db.org/network/224308.BSU29580Putative persulfide ATP pyrophosphatase involved in thiamine biosynthesis and tRNA modification; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of [...]
iscSB protein networkhttps://string-db.org/network/224308.BSU29590Cysteine desulfurase; Catalyzes the removal of elemental sulfur from cysteine to produce alanine.
braB protein networkhttps://string-db.org/network/224308.BSU29600Branched-chain amino acid-Na+ symporter; Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proton motive force.
ezrA protein networkhttps://string-db.org/network/224308.BSU29610Negative regulator of FtsZ ring formation; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Int [...]
hisJ protein networkhttps://string-db.org/network/224308.BSU29620Histidinol phosphate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the PHP hydrolase family. HisK subfamily.
refZ protein networkhttps://string-db.org/network/224308.BSU29630Regulator of FtsZ; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
ytsP protein networkhttps://string-db.org/network/224308.BSU29640Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the free Met sulfoxide reductase family.
ytrP protein networkhttps://string-db.org/network/224308.BSU29650Putative diguanylate cyclase-related enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzym [...]
rpsD protein networkhttps://string-db.org/network/224308.BSU29660Ribosomal protein S4 (BS4); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. S4 represses its own expression; i [...]
tyrS protein networkhttps://string-db.org/network/224308.BSU29670tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
acsA protein networkhttps://string-db.org/network/224308.BSU29680acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reactio [...]
acuA protein networkhttps://string-db.org/network/224308.BSU29690Protein acetyltransferase; Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA v [...]
acuB protein networkhttps://string-db.org/network/224308.BSU29700Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source.
acuC protein networkhttps://string-db.org/network/224308.BSU29710Protein deacetylase; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source; Belongs to the histone deacetylase family.
ytxE protein networkhttps://string-db.org/network/224308.BSU29720Putative flagellar motor apparatus component; May be involved in some transport function; Belongs to the MotB family.
ytxD protein networkhttps://string-db.org/network/224308.BSU29730Putative flagellar motor component; May be involved in some transport function; Belongs to the MotA family.
ccpA protein networkhttps://string-db.org/network/224308.BSU29740Transcriptional regulator (Lacl family); Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under di [...]
aroX protein networkhttps://string-db.org/network/224308.BSU297503-deoxy-D-arabino-heptulosonate 7-phosphate synthase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-I DAHP synthase family.
ytxJ protein networkhttps://string-db.org/network/224308.BSU29760Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232.
ytxH protein networkhttps://string-db.org/network/224308.BSU29770Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16291680, 8733232; To C.plantagineum desiccation-related protein clone PCC3- 06.
ytxG protein networkhttps://string-db.org/network/224308.BSU29780Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232.
murC protein networkhttps://string-db.org/network/224308.BSU29790UDP-N-acetyl muramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
sftA protein networkhttps://string-db.org/network/224308.BSU29805DNA translocase; Required for the accurate completion of chromosome partitioning, in part by promoting efficient resolution of chromosome dimers, before the formation of the division septum. Bind [...]
ytpR protein networkhttps://string-db.org/network/224308.BSU29820Putative tRNA binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
ytpQ protein networkhttps://string-db.org/network/224308.BSU29830Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12719520, 21949854; Belongs to the UPF0354 family.
ytpP protein networkhttps://string-db.org/network/224308.BSU29840Putative thiol-disulfide oxidoreductase with thioredoxin domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product typ [...]
ytoQ protein networkhttps://string-db.org/network/224308.BSU29850Putative enzyme with sugar binding fold; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ytoP protein networkhttps://string-db.org/network/224308.BSU29860Glutamyl aminopeptidase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
ytzB protein networkhttps://string-db.org/network/224308.BSU29870Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
malS protein networkhttps://string-db.org/network/224308.BSU29880NAD-dependent malic enzyme (conversion of malate into pyruvate); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
ytnP protein networkhttps://string-db.org/network/224308.BSU29890Putative metal-dependent hydrolase; Probable hydrolase that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S.griseus. Thus [...]
trmB protein networkhttps://string-db.org/network/224308.BSU29900tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB f [...]
ytzH protein networkhttps://string-db.org/network/224308.BSU29910Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ytmP protein networkhttps://string-db.org/network/224308.BSU29920Putative kinase/phosphotransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belong [...]
amyX protein networkhttps://string-db.org/network/224308.BSU29930Pullulanase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family.
ytlR protein networkhttps://string-db.org/network/224308.BSU29940Putative phospholipid kinase; May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact, is not able to exhibit diacylglycerol kinase activity in vitro.
ytlQ protein networkhttps://string-db.org/network/224308.BSU29950Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ytlP protein networkhttps://string-db.org/network/224308.BSU299602'-5' RNA-ligase family protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
ytkP protein networkhttps://string-db.org/network/224308.BSU29970Putative cysteine synthase-like protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ytjP protein networkhttps://string-db.org/network/224308.BSU29980Putative dipeptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
pbuO protein networkhttps://string-db.org/network/224308.BSU29990Hypoxanthine/guanine permease; Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM.
ythQ protein networkhttps://string-db.org/network/224308.BSU30000Putative ABC transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ythP protein networkhttps://string-db.org/network/224308.BSU30010Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative tr [...]
ytzE protein networkhttps://string-db.org/network/224308.BSU30020Putative transcriptional regulator (DeoR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
ytzG protein networkhttps://string-db.org/network/224308.BSU30035Putative 16S pseudouridylate synthase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ytgP protein networkhttps://string-db.org/network/224308.BSU30050Putative enzyme involved in polysaccharide biosynthesis; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytop [...]
ytfP protein networkhttps://string-db.org/network/224308.BSU30060Putative NAD(FAD) dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
opuD protein networkhttps://string-db.org/network/224308.BSU30070Glycine betaine transporter; High-affinity uptake of glycine betaine. Does not mediate either carnitine or choline uptake; Belongs to the BCCT transporter (TC 2.A.15) family.
yteV protein networkhttps://string-db.org/network/224308.BSU30080Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8990290.
yteU protein networkhttps://string-db.org/network/224308.BSU30090Putative membrane enzyme for rhamnogalaturonan degradation; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: [...]
yteT protein networkhttps://string-db.org/network/224308.BSU30100Putative dehydrogenase of rhamnogalaturonan degradation; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. Belongs to the Gfo/Idh/MocA family.
yteS protein networkhttps://string-db.org/network/224308.BSU30110Putative lipoprotein required for rhamnogalaturonan degradation; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls.
yteR protein networkhttps://string-db.org/network/224308.BSU30120Unsaturated rhamnogalacturonyl hydrolase; Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D-galacturonic acid and L-rhamnose. It cannot act on unsatur [...]
yteP protein networkhttps://string-db.org/network/224308.BSU30135Putative permease; Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane. May play a role in the degradation of typ [...]
ytdP protein networkhttps://string-db.org/network/224308.BSU30150Putative membrane bound transcriptional regulator (AraC/XylS family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Produc [...]
ytcQ protein networkhttps://string-db.org/network/224308.BSU30160Putative ABC transporter (binding lipoprotein); Probably part of a binding-protein-dependent transport system; Belongs to the bacterial solute-binding protein 1 family.
ytcP protein networkhttps://string-db.org/network/224308.BSU30170Putative ABC transporter (permease); Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane; Belongs to the [...]
ytbQ protein networkhttps://string-db.org/network/224308.BSU30180Putative nucleoside-diphosphate-sugar epimerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative e [...]
bioI protein networkhttps://string-db.org/network/224308.BSU30190Cytochrome P450 for pimelic acid formation for biotin biosynthesis; Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynth [...]
bioB protein networkhttps://string-db.org/network/224308.BSU30200Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily [...]
bioD protein networkhttps://string-db.org/network/224308.BSU30210Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ur [...]
bioF protein networkhttps://string-db.org/network/224308.BSU302208-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and [...]
bioK protein networkhttps://string-db.org/network/224308.BSU30230Lysine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from L-lysine to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). B. [...]
bioW protein networkhttps://string-db.org/network/224308.BSU302406-carboxyhexanoate-CoA ligase (pimeloyl-CoA synthase); Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
ytaP protein networkhttps://string-db.org/network/224308.BSU30250Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the dienela [...]
msmR protein networkhttps://string-db.org/network/224308.BSU30260Transcriptional regulator (LacI family); Represses the melibiose operon melREDCA in the absence of melibiose or raffinose. Binds to two binding sites at the promoter region of the operon.
msmE protein networkhttps://string-db.org/network/224308.BSU30270Multiple sugar-binding lipoprotein; Part of the ABC transporter complex MelEDC-MsmX involved in melibiose, raffinose and stachyose import. Binds melibiose, raffinose and stachyose.
amyD protein networkhttps://string-db.org/network/224308.BSU30280Carbohydrate ABC transporter (permease); Part of the ABC transporter complex MelEDC-MsmX involved in melibiose, raffinose and stachyose import. Probably responsible for the translocation of the s [...]
amyC protein networkhttps://string-db.org/network/224308.BSU30290Maltose and multiple sugars ABC transporter (permease); Part of the ABC transporter complex MelEDC-MsmX involved in melibiose, raffinose and stachyose import. Probably responsible for the translo [...]
melA protein networkhttps://string-db.org/network/224308.BSU30300alpha-D-galactoside galactohydrolase; Catalyzes the hydrolysis of melibiose and alpha-galactosides of the raffinose family of oligosaccharides (RFOs) such as raffinose and stachyose. Cannot act o [...]
ytwF protein networkhttps://string-db.org/network/224308.BSU30310Putative sulfur transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
leuS protein networkhttps://string-db.org/network/224308.BSU30320leucyl-tRNA synthetase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.
ytvB protein networkhttps://string-db.org/network/224308.BSU30330Putative conserved membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
ytvA protein networkhttps://string-db.org/network/224308.BSU30340Blue light GTP-binding receptor; Exhibits the same spectroscopical features and blue-light induced photochemistry as plants phototropins, with the reversible formation of a blue-shifted photoprod [...]
yttB protein networkhttps://string-db.org/network/224308.BSU30350Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yttA protein networkhttps://string-db.org/network/224308.BSU30360Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12823818.
bceB protein networkhttps://string-db.org/network/224308.BSU30370ABC transporter (permease); Part of the ABC transporter complex BceAB (TC 3.A.1.123.5) involved in bacitracin export; Belongs to the ABC-4 integral membrane protein family.
bceA protein networkhttps://string-db.org/network/224308.BSU30380Bacitracin ABC efflux transporter (ATP-binding protein); Part of the ABC transporter complex BceAB (TC 3.A.1.123.5) involved in bacitracin export. Responsible for energy coupling to the transport [...]
bceS protein networkhttps://string-db.org/network/224308.BSU30390Sensor protein BceS; Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin.
bceR protein networkhttps://string-db.org/network/224308.BSU30400Sensory transduction protein BceR; Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS, binds to the upstream regio [...]
ytrF protein networkhttps://string-db.org/network/224308.BSU30410Metabolite permease; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
ytrE protein networkhttps://string-db.org/network/224308.BSU30420ABC transporter (ATP-binding protein); Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
ytrD protein networkhttps://string-db.org/network/224308.BSU30430ABC transporter, permease component; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
ytrC protein networkhttps://string-db.org/network/224308.BSU30440ABC transporter, permease component; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
ytrB protein networkhttps://string-db.org/network/224308.BSU30450ABC transporter (ATP-binding protein); Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
ytrA protein networkhttps://string-db.org/network/224308.BSU30460Transcriptional regulator (GntR family); Negatively regulates ABC transporter complex ytrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
BSU30466 protein networkhttps://string-db.org/network/224308.BSU30466Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ytzC protein networkhttps://string-db.org/network/224308.BSU30470Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ytqA protein networkhttps://string-db.org/network/224308.BSU30480Putative Fe-S oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ytqB protein networkhttps://string-db.org/network/224308.BSU30490Putative RNA methylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase su [...]
ytpB protein networkhttps://string-db.org/network/224308.BSU30500Conserved hypothetical protein; Catalyzes the transformation of a linear C35 prenyl diphosphate chain to form tetraprenyl-beta-curcumene.
ytpA protein networkhttps://string-db.org/network/224308.BSU30510Phospholipase component of bacilysocin synthesis or export; Phospholipase involved in the biosynthesis of the antibiotic bacilysocin. It probably catalyzes the hydrolysis of the 2-sn-acyl moiety [...]
ytoA protein networkhttps://string-db.org/network/224308.BSU30520Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the transferase hexapeptide repeat family.
ytnA protein networkhttps://string-db.org/network/224308.BSU30530Putative amino acid permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
asnB protein networkhttps://string-db.org/network/224308.BSU30540Asparagine synthetase; Main asparagine synthetase in vegetative cells.
metK protein networkhttps://string-db.org/network/224308.BSU30550S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet forma [...]
pckA protein networkhttps://string-db.org/network/224308.BSU30560Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucl [...]
ytmB protein networkhttps://string-db.org/network/224308.BSU30570Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ytmA protein networkhttps://string-db.org/network/224308.BSU30580Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the peptida [...]
ytlA protein networkhttps://string-db.org/network/224308.BSU30595Putative ABC transporter component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ytlC protein networkhttps://string-db.org/network/224308.BSU30610Putative ABC transporter component, ATP-binding; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative t [...]
ytlD protein networkhttps://string-db.org/network/224308.BSU30620Putative permease of ABC transporter; Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity).
rppG protein networkhttps://string-db.org/network/224308.BSU30630Nucleoside and RNA triphosphate phosphohydrolase; Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo- dGTP) from DNA and th [...]
ytkC protein networkhttps://string-db.org/network/224308.BSU30640Putative autolytic amidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
dps protein networkhttps://string-db.org/network/224308.BSU30650DNA-protecting protein, ferritin; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
ytzI protein networkhttps://string-db.org/network/224308.BSU30659Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ytkA protein networkhttps://string-db.org/network/224308.BSU30660Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
luxS protein networkhttps://string-db.org/network/224308.BSU30670S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the en [...]
ytjA protein networkhttps://string-db.org/network/224308.BSU30680Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
ytiB protein networkhttps://string-db.org/network/224308.BSU30690Carbonic anhydrase; Reversible hydration of carbon dioxide.
rpmEB protein networkhttps://string-db.org/network/224308.BSU30700Ribosomal protein L31; While neither of the L31 paralogs is essential, this protein does not seem to function as the main L31 protein. Has a higher affinity for 70S ribosomes than the zinc-contai [...]
ythA protein networkhttps://string-db.org/network/224308.BSU30710Putative cytochrome bd menaquinol oxidase subunit I; May have a role in sporulation. Can compensate for the loss of cytochrome aa3; Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
ythB protein networkhttps://string-db.org/network/224308.BSU30720Putative cytochrome bd menaquinol oxidase subunit II; May have a role in sporulation. Can compensate for the loss of cytochrome aa3; Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
ytzL protein networkhttps://string-db.org/network/224308.BSU30739Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
mntD protein networkhttps://string-db.org/network/224308.BSU30740Manganese ABC transporter (permease); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the mem [...]
mntC protein networkhttps://string-db.org/network/224308.BSU30750Manganese ABC transporter (permease); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the mem [...]
mntB protein networkhttps://string-db.org/network/224308.BSU30760Manganese ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for energy coupling to the transport syste [...]
mntA protein networkhttps://string-db.org/network/224308.BSU30770Manganese ABC transporter (manganese binding lipoprotein); Probably part of the ABC transporter complex MntABCD involved in manganese import.
menC protein networkhttps://string-db.org/network/224308.BSU30780O-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
menE protein networkhttps://string-db.org/network/224308.BSU30790O-succinylbenzoic acid-CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
menB protein networkhttps://string-db.org/network/224308.BSU30800Dihydroxynapthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
menH-2 protein networkhttps://string-db.org/network/224308.BSU30810Putative 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydro [...]
menD protein networkhttps://string-db.org/network/224308.BSU308202-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resultin [...]
menF protein networkhttps://string-db.org/network/224308.BSU30830Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
yteA protein networkhttps://string-db.org/network/224308.BSU30840Putative DksA homolog; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
ytdA protein networkhttps://string-db.org/network/224308.BSU30850Putative UTP-glucose-1-phosphate uridylyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putat [...]
ytcA protein networkhttps://string-db.org/network/224308.BSU30860Putative UDP-glucose dehydrogenase; Catalyzes the conversion of UDP-glucose into UDP-glucuronate, one of the precursors of teichuronic acid.
ytcB protein networkhttps://string-db.org/network/224308.BSU30870Putative UDP-glucose epimerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to [...]
ytcC protein networkhttps://string-db.org/network/224308.BSU30880Putative glucosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
ytxO protein networkhttps://string-db.org/network/224308.BSU30890Outer spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
cotS protein networkhttps://string-db.org/network/224308.BSU30900Spore coat protein; Seems to be required for the assembly of the CotSA protein in spores.
cotSA protein networkhttps://string-db.org/network/224308.BSU30910Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase [...]
cotI protein networkhttps://string-db.org/network/224308.BSU30920Spore coat kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
ytaB protein networkhttps://string-db.org/network/224308.BSU30930Putative receptor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc: putative receptor.
glgP protein networkhttps://string-db.org/network/224308.BSU30940Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural subst [...]
glgA protein networkhttps://string-db.org/network/224308.BSU30950Bacterial glycogen (starch) synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose; Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
glgD protein networkhttps://string-db.org/network/224308.BSU30960Glucose-1-phosphate adenylyltransferase (ADP-glucose pyrophosphorylase) beta subunit; Required for the synthesis of glycogen; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferas [...]
glgC protein networkhttps://string-db.org/network/224308.BSU30970Glucose-1-phosphate adenylyltransferase (ADP-glucose pyrophosphorylase) subunit alpha; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produ [...]
glgB protein networkhttps://string-db.org/network/224308.BSU309801,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains [...]
thiT protein networkhttps://string-db.org/network/224308.BSU30990Thiamin permease; Probably a thiamine-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides t [...]
yuaI protein networkhttps://string-db.org/network/224308.BSU31000Putative acetyl-transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to th [...]
yuaG protein networkhttps://string-db.org/network/224308.BSU31010Putative flotillin-like protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
yuaF protein networkhttps://string-db.org/network/224308.BSU31020Putative membrane integrity integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: puta [...]
yuaE protein networkhttps://string-db.org/network/224308.BSU31030Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yuaD protein networkhttps://string-db.org/network/224308.BSU31040Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11886751.
gbsB protein networkhttps://string-db.org/network/224308.BSU31050Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine from choline; Belongs to the iron-containing alcohol dehydrogenase family.
gbsA protein networkhttps://string-db.org/network/224308.BSU31060Glycine betaine aldehyde dehydrogenase, NAD+-dependent; Involved in the biosynthesis of the osmoprotectant glycine betaine from choline. Catalyzes the oxidation of betaine aldehyde to betaine. Sh [...]
yuaC protein networkhttps://string-db.org/network/224308.BSU31070Putative transcriptional regulator; Negatively regulates the expression of the gbsAB and opuB operons. Required to control expression of these genes in response to choline availability. Also requ [...]
bslA protein networkhttps://string-db.org/network/224308.BSU31080Biofilm hydrophobic layer component; Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable a [...]
ktrA protein networkhttps://string-db.org/network/224308.BSU31090Potassium uptake protein; Catalytic subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and p [...]
ktrB protein networkhttps://string-db.org/network/224308.BSU31100Potassium transporter ATPase; Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly i [...]
yubF protein networkhttps://string-db.org/network/224308.BSU31110Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
lytG protein networkhttps://string-db.org/network/224308.BSU31120Exoglucosaminidase; Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Catalyzes the hydrolysis of 1,4-beta-linkages between N-acetyl-D- [...]
yubD protein networkhttps://string-db.org/network/224308.BSU31130Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
cdoA protein networkhttps://string-db.org/network/224308.BSU31140Cysteine dioxygenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
uppP protein networkhttps://string-db.org/network/224308.BSU31150Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
yubA protein networkhttps://string-db.org/network/224308.BSU31160Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yulF protein networkhttps://string-db.org/network/224308.BSU31170Enzyme involved in biofilm formation; Catalyzes the NADPH-dependent reduction of scyllo-inosose (SIS) to scyllo-inositol (SI) in vitro, but is unable to dehydrogenate scyllo-inositol and myo-inos [...]
rhaA protein networkhttps://string-db.org/network/224308.BSU31180L-rhamnose isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the rhamnose isomerase family.
rhaU protein networkhttps://string-db.org/network/224308.BSU31190L-rhamnose mutarotase; Involved in the anomeric conversion of L-rhamnose.
rhaB protein networkhttps://string-db.org/network/224308.BSU31200Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rham [...]
yulB protein networkhttps://string-db.org/network/224308.BSU31210Putative transcriptional regulator (DeoR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
rhaD protein networkhttps://string-db.org/network/224308.BSU31220Putative Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; [...]
tlpB protein networkhttps://string-db.org/network/224308.BSU31230Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside t [...]
mcpA protein networkhttps://string-db.org/network/224308.BSU31240Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside t [...]
tlpA protein networkhttps://string-db.org/network/224308.BSU31250Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside t [...]
mcpB protein networkhttps://string-db.org/network/224308.BSU31260Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside t [...]
tgl protein networkhttps://string-db.org/network/224308.BSU31270Protein-glutamine gamma-glutamyltransferase (transglutaminase); Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links. In wild- [...]
yuzH protein networkhttps://string-db.org/network/224308.BSU31279Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yugU protein networkhttps://string-db.org/network/224308.BSU31280Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0047 family.
yugT protein networkhttps://string-db.org/network/224308.BSU31290Putative oligo-1,6-glucosidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glycosyl hyd [...]
yugS protein networkhttps://string-db.org/network/224308.BSU31300Putative membrane protein involved in divalent ion export; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: [...]
yugP protein networkhttps://string-db.org/network/224308.BSU31310Putative metal-dependent protease/peptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzym [...]
yuzI protein networkhttps://string-db.org/network/224308.BSU31319Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Product type f: factor.
mstX protein networkhttps://string-db.org/network/224308.BSU31321Atypical membrane-integrating protein (Mistic protein); Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer.
yugO protein networkhttps://string-db.org/network/224308.BSU31322Putative potassium channel protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
yugN protein networkhttps://string-db.org/network/224308.BSU31330Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yugM protein networkhttps://string-db.org/network/224308.BSU31340Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
pgi protein networkhttps://string-db.org/network/224308.BSU31350Glucose-6-phosphate isomerase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the GPI family.
yugK protein networkhttps://string-db.org/network/224308.BSU31360Putative NADH-dependent butanol dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enz [...]
yugJ protein networkhttps://string-db.org/network/224308.BSU31370Putative NADH-dependent butanol dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enz [...]
yuzA protein networkhttps://string-db.org/network/224308.BSU31380Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yugI protein networkhttps://string-db.org/network/224308.BSU31390Putative RNA degradation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yugH protein networkhttps://string-db.org/network/224308.BSU31400Putative aspartate aminotransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the class-I [...]
yugG protein networkhttps://string-db.org/network/224308.BSU31410Putative transcriptional regulator (Lrp/AsnC family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putat [...]
yugF protein networkhttps://string-db.org/network/224308.BSU31420Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the DmpD/To [...]
yugE protein networkhttps://string-db.org/network/224308.BSU31430Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
patB protein networkhttps://string-db.org/network/224308.BSU31440Promiscuous cystathionine beta-lyase / cysteine desulfhydrase; Catalyzes the transformation of cystathionine to homocysteine. Also exhibits cysteine desulfhydrase activity in vitro, producing sul [...]
kinB protein networkhttps://string-db.org/network/224308.BSU31450Two-component sensor histidine kinase; Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the KinB activity.
kapB protein networkhttps://string-db.org/network/224308.BSU31460Factor required for KinB signal transduction and activation of the phosphorelay to sporulation; May play a role in the activation or the expression of KinB.
kapD protein networkhttps://string-db.org/network/224308.BSU31470Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation.
yuxJ protein networkhttps://string-db.org/network/224308.BSU31480Putative exporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
pbpD protein networkhttps://string-db.org/network/224308.BSU31490Penicillin-binding protein 4; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; In the C-terminal section; belongs to the transpep [...]
yuxK protein networkhttps://string-db.org/network/224308.BSU31500Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DCC thiol-disulfide oxidoreductase family.
yufK protein networkhttps://string-db.org/network/224308.BSU31510Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yufL protein networkhttps://string-db.org/network/224308.BSU31520Two-component sensor histidine kinase [YufM]; Member of a two-component regulatory system MalK/MalR. Involved in the activation of maeA, maeN and yflS in presence of malate. Probably activates Ma [...]
yufM protein networkhttps://string-db.org/network/224308.BSU31530Two-component response regulator [YufL]; Member of a two-component regulatory system MalK/MalR. Activates transcription of maeA, maeN and yflS in presence of malate by binding to their promoter r [...]
nupN protein networkhttps://string-db.org/network/224308.BSU31540Lipoprotein involved in guanosine transport; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type lp: lipoprotein.
nupO protein networkhttps://string-db.org/network/224308.BSU31550Guanosine ABC transporter (ATP-binding protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter; Belongs to the ABC transporter superfamily.
nupP protein networkhttps://string-db.org/network/224308.BSU31560Permease of ABC guanosine transporter; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarit [...]
nupQ protein networkhttps://string-db.org/network/224308.BSU31570Permease of ABC guanosine transporter; Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrates across the membrane (By similarity).
maeN protein networkhttps://string-db.org/network/224308.BSU31580Na+/malate symporter; Acts as a Na(+)-malate symporter, as it catalyzes malate- dependent uptake of Na(+) and Na(+)-dependent uptake of malate.
yufS protein networkhttps://string-db.org/network/224308.BSU31590Putative bacteriocin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
mrpA protein networkhttps://string-db.org/network/224308.BSU31600Sodium transporter component of a Na+/H+ antiporter; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resi [...]
mrpB protein networkhttps://string-db.org/network/224308.BSU31610Na+/H+ antiporter complex; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in [...]
mrpC protein networkhttps://string-db.org/network/224308.BSU31620Component of Na+/H+ antiporter; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor ro [...]
mrpD protein networkhttps://string-db.org/network/224308.BSU31630Proton transporter component of Na+/H+ antiporter; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resist [...]
mrpE protein networkhttps://string-db.org/network/224308.BSU31640Non essential component of Na+/H+ antiporter; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance [...]
mrpF protein networkhttps://string-db.org/network/224308.BSU31650Efflux transporter for Na+ and cholate; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a [...]
mrpG protein networkhttps://string-db.org/network/224308.BSU31660Non essential component of Na+/H+ antiporter; May enhance MrpA stability, assembly, or function. May play chaperone or assembly roles for MrpA and perhaps for other mrp proteins.
yuxO protein networkhttps://string-db.org/network/224308.BSU31670Putative esterase; Is not required for competence.
comA protein networkhttps://string-db.org/network/224308.BSU31680Two-component response regulator; Response regulator in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic compete [...]
comP protein networkhttps://string-db.org/network/224308.BSU31690Two-component sensor histidine kinase; Sensor in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Pl [...]
comX protein networkhttps://string-db.org/network/224308.BSU31700Competence pheromone precursor (pheromone peptide aa 46->55, geranyl-modified); Part of a major quorum-sensing system that regulates the development of genetic competence. Acts through the activa [...]
comQ protein networkhttps://string-db.org/network/224308.BSU31710Isoprenyl transferase (pre-ComX modification); Involved in the maturation of ComX, part of a major quorum- sensing system that regulates the development of genetic competence.
degQ protein networkhttps://string-db.org/network/224308.BSU31720Pleiotropic regulator; Stimulates the phosphotransfer from phospho-DegS to DegU. Affects protease and levansucrose production.
yuzC protein networkhttps://string-db.org/network/224308.BSU31730Inner spore coat protein; Evidence 2b: Function of strongly homologous gene; Product type cp: cell process.
yuxH protein networkhttps://string-db.org/network/224308.BSU31740Putative phosphodiesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
pncB protein networkhttps://string-db.org/network/224308.BSU31750Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase [...]
pncA protein networkhttps://string-db.org/network/224308.BSU31760Nicotinamidase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the isochorismatase family.
yueI protein networkhttps://string-db.org/network/224308.BSU31770Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yueH protein networkhttps://string-db.org/network/224308.BSU31780Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yueG protein networkhttps://string-db.org/network/224308.BSU31790Putative spore germination protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belong [...]
yueF protein networkhttps://string-db.org/network/224308.BSU31800Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yuzE protein networkhttps://string-db.org/network/224308.BSU31810Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yuzF protein networkhttps://string-db.org/network/224308.BSU31820Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yueE protein networkhttps://string-db.org/network/224308.BSU31830Putative metal-dependent phosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yueD protein networkhttps://string-db.org/network/224308.BSU31840Putative aromatic compound reductase; Reduces benzil stereospecifically to (S)-benzoin.
yueC protein networkhttps://string-db.org/network/224308.BSU31850Hypothetical protein; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss).
yueB protein networkhttps://string-db.org/network/224308.BSU31860Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversi [...]
yukB protein networkhttps://string-db.org/network/224308.BSU31875Putative cell division protein; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss).
yukC protein networkhttps://string-db.org/network/224308.BSU31890Putative membrane-associated enzyme involved in bacteriocin production; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss).
yukD protein networkhttps://string-db.org/network/224308.BSU31900Putative bacteriocin; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Belongs to the EsaB family.
yukE protein networkhttps://string-db.org/network/224308.BSU31910Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15576783.
yukF protein networkhttps://string-db.org/network/224308.BSU31920Putative transcriptional regulator; Mediates ald expression in response to alanine availability and is important for normal sporulation in B.subtilis. Belongs to the CdaR family.
ald protein networkhttps://string-db.org/network/224308.BSU31930L-alanine dehydrogenase; Catalyzes the reversible oxidative deamination of L-alanine to pyruvate. This enzyme is a key factor in the assimilation of L- alanine as an energy source through the tri [...]
yukJ protein networkhttps://string-db.org/network/224308.BSU31945Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ybdZ protein networkhttps://string-db.org/network/224308.BSU31959Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11112781.
dhbF protein networkhttps://string-db.org/network/224308.BSU31960Siderophore 2,3-dihydroxybenzoate-glycine-threonine trimeric ester bacillibactin synthetase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrie [...]
dhbB protein networkhttps://string-db.org/network/224308.BSU31970Isochorismatase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
dhbE protein networkhttps://string-db.org/network/224308.BSU319802,3-dihydroxybenzoate-AMP ligase; Involved in the biosynthesis of the catecholic siderophore bacillibactin. Catalyzes the activation of the carboxylate group of 2,3-dihydroxy-benzoate (DHB), via [...]
dhbC protein networkhttps://string-db.org/network/224308.BSU31990Isochorismate synthase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the isochorismate synthase family.
dhbA protein networkhttps://string-db.org/network/224308.BSU320002,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the short-chain dehy [...]
besA protein networkhttps://string-db.org/network/224308.BSU32010Bacillibactin trilactone hydrolase; Catalyzes the hydrolysis of the trilactone cycle of ferri- bacillibactin (ferri-BB) complex, leading to the formation of bacillibactin monomers and to cytosoli [...]
yuiH protein networkhttps://string-db.org/network/224308.BSU32020Putative enzymes similar to sulfite oxidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzym [...]
bioYB protein networkhttps://string-db.org/network/224308.BSU32030Putative biotin transporter; Putative biotin transporter; Belongs to the BioY family.
yuiF protein networkhttps://string-db.org/network/224308.BSU32040Amino acid transporter; Evidence 2b: Function of strongly homologous gene; Product type t: transporter.
pepA protein networkhttps://string-db.org/network/224308.BSU32050Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides ( [...]
yuiD protein networkhttps://string-db.org/network/224308.BSU32060Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yuiC protein networkhttps://string-db.org/network/224308.BSU32070Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yuiB protein networkhttps://string-db.org/network/224308.BSU32080Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yuiA protein networkhttps://string-db.org/network/224308.BSU32090Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yumB protein networkhttps://string-db.org/network/224308.BSU32100Putative NAD-disulfide oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yumC protein networkhttps://string-db.org/network/224308.BSU32110ferredoxin-NADP+ reductase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the ferredoxin--NADP reductase type 2 family.
yuzG protein networkhttps://string-db.org/network/224308.BSU32120Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
guaC protein networkhttps://string-db.org/network/224308.BSU32130GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and [...]
paiB protein networkhttps://string-db.org/network/224308.BSU32140Putative enzyme; Involved in the reduction of extracellular and cell- associated protease levels, as well as in the reduced levels of alpha- amylase, levansucrase, alkaline phosphatase and sporul [...]
paiA protein networkhttps://string-db.org/network/224308.BSU32150Polyamine N-acetyltransferase; Involved in the protection against polyamine toxicity by regulating their concentration. Also could be involved in the negative control of sporulation as well as pr [...]
sufA protein networkhttps://string-db.org/network/224308.BSU32160Chaperone involved in Fe-S cluster assembly; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; factor.
dapF protein networkhttps://string-db.org/network/224308.BSU32170Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
yutK protein networkhttps://string-db.org/network/224308.BSU32180Putative Na+(H+)/nucleoside cotransporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transpo [...]
yuzB protein networkhttps://string-db.org/network/224308.BSU32190Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0349 family.
yutJ protein networkhttps://string-db.org/network/224308.BSU32200Putative NADH dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yuzD protein networkhttps://string-db.org/network/224308.BSU32210Putative sulfur oxido-reduction management enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yutI protein networkhttps://string-db.org/network/224308.BSU32220Putative iron-sulfur scaffold protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
yuxL protein networkhttps://string-db.org/network/224308.BSU32230Putative acylaminoacyl-peptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase [...]
thrB protein networkhttps://string-db.org/network/224308.BSU32240Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
thrC protein networkhttps://string-db.org/network/224308.BSU32250Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
hom protein networkhttps://string-db.org/network/224308.BSU32260Homoserine dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
yutH protein networkhttps://string-db.org/network/224308.BSU32270Spore coat-associated protein; Involved in sporulation; Belongs to the CotS family.
yutG protein networkhttps://string-db.org/network/224308.BSU32280Putative phosphatidylglycerophosphatase A; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; [...]
yutF protein networkhttps://string-db.org/network/224308.BSU32290Putative p-nitrophenyl phosphatase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family.
yutE protein networkhttps://string-db.org/network/224308.BSU32300Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0331 family.
yutD protein networkhttps://string-db.org/network/224308.BSU32310Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12770717.
yutC protein networkhttps://string-db.org/network/224308.BSU32320Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
lipA protein networkhttps://string-db.org/network/224308.BSU32330Lipoyl synthase (lipoic acid synthetase); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate [...]
lytH protein networkhttps://string-db.org/network/224308.BSU32340Sporulation-specific L-Ala-D-Glu endopeptidase; L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, [...]
yunB protein networkhttps://string-db.org/network/224308.BSU32350Putative protein involved in spore formation; Required for sporulation.
yunC protein networkhttps://string-db.org/network/224308.BSU32360Putative RNA binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
yunD protein networkhttps://string-db.org/network/224308.BSU32370Putative nuclease/nucleotidase/phosphoesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative en [...]
yunE protein networkhttps://string-db.org/network/224308.BSU32380Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yunF protein networkhttps://string-db.org/network/224308.BSU32390Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0759 family.
yunG protein networkhttps://string-db.org/network/224308.BSU32400Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
pucH protein networkhttps://string-db.org/network/224308.BSU32410Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
pucR protein networkhttps://string-db.org/network/224308.BSU32420Transcriptional regulator of the purine degradation operon; Activates the expression of pucFG, pucH, pucI, pucJKLM and guaD, while it represses pucABCDE and its own expression. Belongs to the Cda [...]
pucJ protein networkhttps://string-db.org/network/224308.BSU32430Uric acid permease; Uptake of uric acid.
pucK protein networkhttps://string-db.org/network/224308.BSU32440Uric acid permease; Uptake of uric acid.
pucL protein networkhttps://string-db.org/network/224308.BSU32450Urate oxidase with peroxide reductase N-terminal domain; Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective de [...]
pucM protein networkhttps://string-db.org/network/224308.BSU324605-hydroxyisourate hydrolase; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
yuzJ protein networkhttps://string-db.org/network/224308.BSU32469Putative type I toxin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
pucE protein networkhttps://string-db.org/network/224308.BSU32470Xanthine dehydrogenase, iron-sulfur subunit; Oxidizes hypoxanthine and xanthine to uric acid.
pucD protein networkhttps://string-db.org/network/224308.BSU32480Xanthine dehydrogenase, substrate and molybdenum cofactor subunit; Oxidizes hypoxanthine and xanthine to uric acid. Belongs to the xanthine dehydrogenase family.
pucC protein networkhttps://string-db.org/network/224308.BSU32490Xanthine dehydrogenase, FAD-binding subunit; Oxidizes hypoxanthine and xanthine to uric acid.
pucB protein networkhttps://string-db.org/network/224308.BSU32500Enzyme for molybdopterin cofactor synthesis required for xanthine dehydrogenase; Required for xanthine dehydrogenase activity. Could be involved in formation of the molybdenum cofactor required b [...]
pucA protein networkhttps://string-db.org/network/224308.BSU32510Xanthine dehydrogenase molybdopterin recruitment factor; Oxidizes hypoxanthine and xanthine to uric acid. PucA subunit could exert a molybdenum cofactor recruiting function.
pucG protein networkhttps://string-db.org/network/224308.BSU32520Vitamin B6-dependent (S)-ureidoglycine glyoxylate aminotransferase; Catalyzes the transamination between an unstable intermediate ((S)-ureidoglycine) and the end product of purine catabolism (gly [...]
pucF protein networkhttps://string-db.org/network/224308.BSU32530Allantoate amidohydrolase; Involved in the anaerobic nitrogen utilization via the assimilation of allantoin. Catalyzes specifically the hydrolysis of allantoate to yield CO2, NH3 and S-ureidoglyc [...]
bsn protein networkhttps://string-db.org/network/224308.BSU32540Extracellular ribonuclease; Mg(2+)-activated ribonuclease which hydrolyzes RNA apparently nonspecifically into oligonucleotides with 5'-terminal phosphate.
yurJ protein networkhttps://string-db.org/network/224308.BSU32550Putative multiple sugar ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type [...]
frlR protein networkhttps://string-db.org/network/224308.BSU32560FrlR transcriptional regulator (GntR family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
frlD protein networkhttps://string-db.org/network/224308.BSU32570Fructoselysine kinase; Catalyzes the phosphorylation of a range of fructosamines to fructosamine 6-phosphates; Belongs to the carbohydrate kinase PfkB family.
frlM protein networkhttps://string-db.org/network/224308.BSU32580Fructose-amino acid permease; Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane; Belongs to t [...]
frlN protein networkhttps://string-db.org/network/224308.BSU32590Fructose-amino acid permease; Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane; Belongs to t [...]
frlO protein networkhttps://string-db.org/network/224308.BSU32600Fructose amino acid-binding lipoprotein; Probably part of the binding-protein-dependent transport system YurMNO; Belongs to the bacterial solute-binding protein 1 family.
frlB protein networkhttps://string-db.org/network/224308.BSU32610fructoselysine-6-P-deglycase; Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid.
yurQ protein networkhttps://string-db.org/network/224308.BSU32620Putative excinuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yurR protein networkhttps://string-db.org/network/224308.BSU32630Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
sspG protein networkhttps://string-db.org/network/224308.BSU32640Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
yurS protein networkhttps://string-db.org/network/224308.BSU32650Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 9852018.
yurT protein networkhttps://string-db.org/network/224308.BSU32660Putative methylglyoxalase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glyoxalase I fami [...]
yuzN protein networkhttps://string-db.org/network/224308.BSU32669Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
sufB protein networkhttps://string-db.org/network/224308.BSU32670FeS cluster formation protein; The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair o [...]
sufU protein networkhttps://string-db.org/network/224308.BSU32680Iron-sulfur cluster assembly scaffold protein; Its function is controversial. Has been generally assumed to be an iron-sulfur cluster assembly scaffold protein , but more recent evidence suggest [...]
sufS protein networkhttps://string-db.org/network/224308.BSU32690Cysteine desulfurase; Enzyme able to deliver sulfur to partners involved in Fe-S cluster assembly. Catalyzes the removal of elemental sulfur atoms from L-cysteine to produce L-alanine. Activity i [...]
sufD protein networkhttps://string-db.org/network/224308.BSU32700FeS assembly protein SufD; The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of ox [...]
sufC protein networkhttps://string-db.org/network/224308.BSU32710Sulfur mobilizing ABC protein, ATPase; Evidence 2b: Function of strongly homologous gene; enzyme; Belongs to the ABC transporter superfamily. Ycf16 family.
yuzK protein networkhttps://string-db.org/network/224308.BSU32719Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yurZ protein networkhttps://string-db.org/network/224308.BSU32720Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
metQ protein networkhttps://string-db.org/network/224308.BSU32730Methionine ABC transporter, substrate binding lipoprotein; Part of the ABC transporter complex MetNPQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound pe [...]
metP protein networkhttps://string-db.org/network/224308.BSU32740Methionine ABC transporter, permease component; Part of the ABC transporter complex MetNPQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (P [...]
metN protein networkhttps://string-db.org/network/224308.BSU32750Methionine ABC transporter (ATP-binding protein); Part of the ABC transporter complex MetNPQ involved in methionine import. Responsible for energy coupling to the transport system (Probable). It [...]
yusD protein networkhttps://string-db.org/network/224308.BSU32760Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yusE protein networkhttps://string-db.org/network/224308.BSU32770Putative thiol-disulfide oxidoreductase with thioredoxin domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative en [...]
yusF protein networkhttps://string-db.org/network/224308.BSU32780Putative ribonuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yusG protein networkhttps://string-db.org/network/224308.BSU32790Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
gcvH protein networkhttps://string-db.org/network/224308.BSU32800Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
yusI protein networkhttps://string-db.org/network/224308.BSU32810Putative oxidoreductase with thioredoxin domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative e [...]
fadE protein networkhttps://string-db.org/network/224308.BSU32820acyl-CoA dehydrogenase (FAD dependent); Involved in the degradation of long-chain fatty acids.
fadA protein networkhttps://string-db.org/network/224308.BSU32830acetyl-CoA C-acyltransferase; Involved in the degradation of long-chain fatty acids; Belongs to the thiolase-like superfamily. Thiolase family.
fadN protein networkhttps://string-db.org/network/224308.BSU32840enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Involved in the degradation of long-chain fatty acids; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
yuzL protein networkhttps://string-db.org/network/224308.BSU32849Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17189250.
putM protein networkhttps://string-db.org/network/224308.BSU32850Proline dehydrogenase 1; Converts proline to delta-1-pyrroline-5-carboxylate.
yuzM protein networkhttps://string-db.org/network/224308.BSU32859Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yusN protein networkhttps://string-db.org/network/224308.BSU32860Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yusO protein networkhttps://string-db.org/network/224308.BSU32870Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
yusP protein networkhttps://string-db.org/network/224308.BSU32880Putative multidrug-efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter [...]
yusQ protein networkhttps://string-db.org/network/224308.BSU32890Putative tautomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the 4-oxa [...]
yusR protein networkhttps://string-db.org/network/224308.BSU32900Putative 3-oxoacyl-acyl-carrier protein reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative [...]
yusS protein networkhttps://string-db.org/network/224308.BSU32910Putative 3-oxoacyl-acyl-carrier protein reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative [...]
yusT protein networkhttps://string-db.org/network/224308.BSU32920Putative transcriptional regulator (LysR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
yusU protein networkhttps://string-db.org/network/224308.BSU32930Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yusV protein networkhttps://string-db.org/network/224308.BSU32940iron(III)-siderophore transporter (ATP binding component); Provides the ATPase subunit for at least 2 ABC transporter complexes; YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderop [...]
yusW protein networkhttps://string-db.org/network/224308.BSU32950Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
yusZ protein networkhttps://string-db.org/network/224308.BSU32980Oligoendopeptidase; Evidence 7: Gene remnant; Product type e: enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
mrgA protein networkhttps://string-db.org/network/224308.BSU32990Metalloregulation DNA-binding stress protein; Forms highly stable, multimeric protein-DNA complexes which accumulate in stationary-phase cells and protect against oxidative killing; Belongs to th [...]
htrB protein networkhttps://string-db.org/network/224308.BSU33000HtrA-like serine protease; Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a p [...]
cssR protein networkhttps://string-db.org/network/224308.BSU33010Two-component response regulator; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress.
cssS protein networkhttps://string-db.org/network/224308.BSU33020Two-component sensor histidine kinase; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. Required for the transcription of htr [...]
yuzO protein networkhttps://string-db.org/network/224308.BSU33029Regulator of SpxA degradation; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
yuxN protein networkhttps://string-db.org/network/224308.BSU33030Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
fumC protein networkhttps://string-db.org/network/224308.BSU33040Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
yvzF protein networkhttps://string-db.org/network/224308.BSU33049Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
gerAA protein networkhttps://string-db.org/network/224308.BSU33050Component of the GerA germination receptor; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to a [...]
gerAB protein networkhttps://string-db.org/network/224308.BSU33060Component of the germination receptor GerA; Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a rece [...]
gerAC protein networkhttps://string-db.org/network/224308.BSU33070Component of the germination receptor GerA; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to a [...]
liaR protein networkhttps://string-db.org/network/224308.BSU33080Two-component response regulator [YvqE] responding to cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antib [...]
liaS protein networkhttps://string-db.org/network/224308.BSU33090Two-component sensor histidine kinase [YvqC] sensing cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibi [...]
liaF protein networkhttps://string-db.org/network/224308.BSU33100Integral inner membrane protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type m: membrane component.
liaG protein networkhttps://string-db.org/network/224308.BSU33110Conserved hypothetical protein (response to antibiotic stress); Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187.
liaH protein networkhttps://string-db.org/network/224308.BSU33120Modulator of liaIHGFSR (yvqIHGFEC) operon expression; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
liaI protein networkhttps://string-db.org/network/224308.BSU33130Permease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter.
yvqJ protein networkhttps://string-db.org/network/224308.BSU33140Putative efflux protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
pduO protein networkhttps://string-db.org/network/224308.BSU33150Putative ATP:cob(I)alamin adenosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e: enzyme.
yvrA protein networkhttps://string-db.org/network/224308.BSU33160Putative vitamin B12 transport system, ATPase component; Probably part of an ABC transporter complex. Probably responsible for energy coupling to the transport system (By similarity).
yvrB protein networkhttps://string-db.org/network/224308.BSU33170Putative vitamin B12 permease; Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane (By similarity).
yvrC protein networkhttps://string-db.org/network/224308.BSU33180Putative lipoprotein binding vitamin B12; Probably part of an ABC transporter complex.
yvrD protein networkhttps://string-db.org/network/224308.BSU33190Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydro [...]
yvrE protein networkhttps://string-db.org/network/224308.BSU33200Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the SMP-30/CGR1 family.
yvrG protein networkhttps://string-db.org/network/224308.BSU33210Two-component sensor histidine kinase YvrG innvolved in cell wall processes [YvrH]; Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA [...]
yvrH protein networkhttps://string-db.org/network/224308.BSU33221Two-component response regulator YvrH involved in cell wall processes [YvrG]; Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA [...]
rsoA protein networkhttps://string-db.org/network/224308.BSU33222Regulator of sigma-O; Together with RNA polymerase sigma factor SigO, positively regulates the expression of at least three operons, including oxdC- yvrL, sigO-rsoA and yvrJ. Required for the aci [...]
sigO protein networkhttps://string-db.org/network/224308.BSU33230Alternative sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Together with its coactivator RsoA [...]
yvrJ protein networkhttps://string-db.org/network/224308.BSU33239Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 18573182, 19047353.
oxdC protein networkhttps://string-db.org/network/224308.BSU33240Oxalate decarboxylase; Converts oxalate to formate and CO(2) in an O(2)-dependent reaction. Can also catalyze minor side reactions: oxalate oxidation to produce H(2)O(2), and oxalate-dependent, H [...]
yvrL protein networkhttps://string-db.org/network/224308.BSU33250Putative integral inner membrane protein; Negatively regulates RNA polymerase sigma factor SigO- dependent transcription. Prevents the expression or secretion of OxdC under nonstress conditions. [...]
yvrN protein networkhttps://string-db.org/network/224308.BSU33260Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative tr [...]
yvrO protein networkhttps://string-db.org/network/224308.BSU33270Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belong [...]
yvrP protein networkhttps://string-db.org/network/224308.BSU33280Putative ABC transporter component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
fhuC protein networkhttps://string-db.org/network/224308.BSU33290Ferrichrome ABC transporter (ATP-binding protein); Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system (By [...]
fhuG protein networkhttps://string-db.org/network/224308.BSU33300Ferrichrome ABC transporter (permease); Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [...]
fhuB protein networkhttps://string-db.org/network/224308.BSU33310Ferrichrome ABC transporter (permease); Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [...]
fhuD protein networkhttps://string-db.org/network/224308.BSU33320Ferrichrome ABC transporter (ferrichrome-binding lipoprotein); Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and tran [...]
lysP protein networkhttps://string-db.org/network/224308.BSU33330Lysine permease; Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway; Belongs to the amino acid-polyam [...]
sspJ protein networkhttps://string-db.org/network/224308.BSU33340Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
yvsG protein networkhttps://string-db.org/network/224308.BSU33350Putative membrane hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ltaSP protein networkhttps://string-db.org/network/224308.BSU33360Primase of polyglycerolphosphate lipoteichoic acid (LTA) synthesis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the LTA synthase fa [...]
yvgK protein networkhttps://string-db.org/network/224308.BSU33370Putative molybdate binding regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
yvgL protein networkhttps://string-db.org/network/224308.BSU33380Putative molybdate-binding lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
yvgM protein networkhttps://string-db.org/network/224308.BSU33390Putative molybdenum transport permease; could be part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the memb [...]
yvgN protein networkhttps://string-db.org/network/224308.BSU33400Glyoxal/methylglyoxal reductase; Reduces glyoxal and methylglyoxal (2-oxopropanal). Is not involved in the vitamin B6 biosynthesis; Belongs to the aldo/keto reductase family.
yvgO protein networkhttps://string-db.org/network/224308.BSU33410Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11988534.
nhaK protein networkhttps://string-db.org/network/224308.BSU33420Na+/H+ antiporter; Transporter involved in the efflux of sodium, potassium, lithium and rubidium.
cysI protein networkhttps://string-db.org/network/224308.BSU33430Sulfite reductase (hemoprotein beta-subunit); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required [...]
cysJ protein networkhttps://string-db.org/network/224308.BSU33440Sulfite reductase (flavoprotein alpha-subunit); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities require [...]
helD protein networkhttps://string-db.org/network/224308.BSU33450DNA 3'-5' helicase IV; Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP.
yvgT protein networkhttps://string-db.org/network/224308.BSU33460Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
bdbC protein networkhttps://string-db.org/network/224308.BSU33470Thiol-disulfide oxidoreductase; Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. Not normally required for production of the [...]
bdbD protein networkhttps://string-db.org/network/224308.BSU33480Thiol-disulfide oxidoreductase; Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. May be required for the stability of secret [...]
copB protein networkhttps://string-db.org/network/224308.BSU33490copper(I)-transporting ATPase; Couples the hydrolysis of ATP with the transport of cadmium, zinc and cobalt out of the cell. Does not seem to transport copper.
copA protein networkhttps://string-db.org/network/224308.BSU33500Copper transporter ATPase; Involved in copper export.
copZ protein networkhttps://string-db.org/network/224308.BSU33510Copper insertion chaperone and transporter component; Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-transporting ATPase CopA. Func [...]
csoR protein networkhttps://string-db.org/network/224308.BSU33520Repressor of copper utilisation proteins; Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of [...]
yvaA protein networkhttps://string-db.org/network/224308.BSU33530Putative oxidoreductase; Catalyzes the reversible NADPH-dependent reduction of scyllo- inosose (SIS) to scyllo-inositol (SI). Cannot use NADH instead of NADPH. May be involved in reduction of not [...]
yvaB protein networkhttps://string-db.org/network/224308.BSU33540NADH:dichloroindophenol oxidoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for [...]
yvaC protein networkhttps://string-db.org/network/224308.BSU33550Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yvaD protein networkhttps://string-db.org/network/224308.BSU33560Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yvaE protein networkhttps://string-db.org/network/224308.BSU33570Putative metabolite-efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporte [...]
yvaF protein networkhttps://string-db.org/network/224308.BSU33580Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
yvaG protein networkhttps://string-db.org/network/224308.BSU33590Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the sh [...]
smpB protein networkhttps://string-db.org/network/224308.BSU33600tmRNA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. t [...]
rnr protein networkhttps://string-db.org/network/224308.BSU33610Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
yvaK protein networkhttps://string-db.org/network/224308.BSU33620Carboxylesterase; Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher ch [...]
secG protein networkhttps://string-db.org/network/224308.BSU33630Preprotein translocase subunit; Involved in protein export. Participates in an early event of protein translocation (By similarity).
yvaM protein networkhttps://string-db.org/network/224308.BSU33640Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yvzC protein networkhttps://string-db.org/network/224308.BSU33650Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
rghRA protein networkhttps://string-db.org/network/224308.BSU33660Transcriptional repressor; Represses the expression of yvaM and both rapG and rapH. Binds directly to the promoter regions of yvaM, rapG and rapH.
rghRB protein networkhttps://string-db.org/network/224308.BSU33670Putative transcriptional repressor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
yvaP protein networkhttps://string-db.org/network/224308.BSU33680Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
yvaQ protein networkhttps://string-db.org/network/224308.BSU33690Putative methyl-accepting transducer; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside [...]
opuBD protein networkhttps://string-db.org/network/224308.BSU33700Choline ABC transporter (permease); Involved in a high affinity multicomponent binding-protein- dependent transport system for choline; probably responsible for the translocation of the substrate [...]
opuBC protein networkhttps://string-db.org/network/224308.BSU33710Choline ABC transporter (choline-binding lipoprotein); Member of a high affinity multicomponent binding-protein- dependent transport system for choline.
opuBB protein networkhttps://string-db.org/network/224308.BSU33720Choline ABC transporter (permease); Involved in a high affinity multicomponent binding-protein- dependent transport system for choline; probably responsible for the translocation of the substrate [...]
opuBA protein networkhttps://string-db.org/network/224308.BSU33730Choline ABC transporter (ATP-binding protein); Involved in a high affinity multicomponent binding-protein- dependent transport system for choline. Probably responsible for energy coupling to the [...]
yvaV protein networkhttps://string-db.org/network/224308.BSU33740Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator; Bel [...]
sdpA protein networkhttps://string-db.org/network/224308.BSU33750Export of killing factor; Required for the maturation of SdpC to SDP. Not required for SdpC signal peptide cleavage, secretion from the cell or disulfide bond formation.
sdpB protein networkhttps://string-db.org/network/224308.BSU33760Exporter of killing factor SpbC; Required for the maturation of SdpC to SDP. Not required for SdpC signal peptide cleavage, secretion from the cell or disulfide bond formation.
spbC protein networkhttps://string-db.org/network/224308.BSU33770Killing factor SdpC; Produces a 42-residue extracellular sporulation delaying protein (SDP) that collapses the proton motive force (probably both the membrane potential and pH gradient) across th [...]
sdpI protein networkhttps://string-db.org/network/224308.BSU33780Integral membrane regulator of autophagy; Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a rec [...]
sdpR protein networkhttps://string-db.org/network/224308.BSU33790Transcriptional regulator (ArsR family); Represses the transcription of the sdpIR operon and of several other operons that probably contribute to delaying commitment to sporulation.
opuCD protein networkhttps://string-db.org/network/224308.BSU33800Glycine betaine/carnitine/choline/choline sulfate ABC transporter (permease); Involved in a high affinity multicomponent binding-protein- dependent transport system for glycine betaine, carnitine [...]
opuCC protein networkhttps://string-db.org/network/224308.BSU33810Glycine betaine/carnitine/choline-binding protein OpuCC; Member of a high affinity multicomponent binding-protein- dependent transport system for glycine betaine, carnitine, and choline. Belongs [...]
opuCB protein networkhttps://string-db.org/network/224308.BSU33820Glycine betaine/carnitine/choline/choline sulfate ABC transporter (permease); Involved in a high affinity multicomponent binding-protein- dependent transport system for glycine betaine, carnitine [...]
opuCA protein networkhttps://string-db.org/network/224308.BSU33830Glycine betaine/carnitine/choline/choline sulfate ABC transporter (ATP-binding protein); Involved in a high affinity multicomponent binding-protein- dependent transport system for glycine betaine [...]
yvbF protein networkhttps://string-db.org/network/224308.BSU33840Putative transcriptional regulator; Negatively regulates the transcription of the opuC operon. In the absence of GbsR, is also a negative regulator of the opuB operon. Binds to an inverted repeat [...]
yvbG protein networkhttps://string-db.org/network/224308.BSU33850Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yvbH protein networkhttps://string-db.org/network/224308.BSU33860Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yvbI protein networkhttps://string-db.org/network/224308.BSU33870Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yvbJ protein networkhttps://string-db.org/network/224308.BSU33880Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15155184.
yvbK protein networkhttps://string-db.org/network/224308.BSU33890Putative acyltransferase; Probable N-acetyltransferase.
eno protein networkhttps://string-db.org/network/224308.BSU33900Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
pgm protein networkhttps://string-db.org/network/224308.BSU33910Phosphoglycerate mutase; Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
tpiA protein networkhttps://string-db.org/network/224308.BSU33920Triose phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to th [...]
pgk protein networkhttps://string-db.org/network/224308.BSU33930Phosphoglycerate kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the phosphoglycerate kinase family.
gapA protein networkhttps://string-db.org/network/224308.BSU33940Glyceraldehyde-3-phosphate dehydrogenase; Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3- bisphosphoglycerate (BPG) using the cofac [...]
cggR protein networkhttps://string-db.org/network/224308.BSU33950Transcriptional regulator of gapA; In the absence of glucose, represses the transcription of the gapA operon, which encodes five key glycolytic enzymes. Binds specifically to the cggR-gapA promot [...]
araE protein networkhttps://string-db.org/network/224308.BSU33960Arabinose-related compounds permease; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system).
araR protein networkhttps://string-db.org/network/224308.BSU33970Transcriptional repressor of the ara regulon (LacI family); Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the prom [...]
yvbT protein networkhttps://string-db.org/network/224308.BSU33980Putative alkanal monooxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; To bacterial alkanal monoox [...]
yvbU protein networkhttps://string-db.org/network/224308.BSU33990Putative transcriptional regulator (LysR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
cyeB protein networkhttps://string-db.org/network/224308.BSU34000Cysteine and O-acetylserine efflux permease; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; transporter.
yvbW protein networkhttps://string-db.org/network/224308.BSU34010Putative leucine permease; May participate in leucine metabolism. May transport leucine or a compound related to leucine metabolism; Belongs to the amino acid-polyamine-organocation (APC) superfa [...]
yvbX protein networkhttps://string-db.org/network/224308.BSU34020Putative epimerase modification of peptidoglycan; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs t [...]
lutC protein networkhttps://string-db.org/network/224308.BSU34030Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon [...]
lutB protein networkhttps://string-db.org/network/224308.BSU34040Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during [...]
lutA protein networkhttps://string-db.org/network/224308.BSU34050Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source [...]
yvfU protein networkhttps://string-db.org/network/224308.BSU34060Two-component response regulator [YvfT]; Member of the two-component regulatory system YvfT/YvfU.
yvfT protein networkhttps://string-db.org/network/224308.BSU34070Two-component sensor histidine kinase [YvfU]; Member of the two-component regulatory system YvfT/YvfU. Probably activates YvfU by phosphorylation.
yvfS protein networkhttps://string-db.org/network/224308.BSU34080Putative ABC transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yvfR protein networkhttps://string-db.org/network/224308.BSU34090Putative ABC efflux transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: puta [...]
rsbQ protein networkhttps://string-db.org/network/224308.BSU34100Regulator of RsbP phosphatase; Positive regulator required for energy stress activation of the sigma-B transcription factor. Could be required for RsbP phosphatase activity; Belongs to the AB hyd [...]
rsbP protein networkhttps://string-db.org/network/224308.BSU34110Serine phosphatase; Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to energy stress.
ganB protein networkhttps://string-db.org/network/224308.BSU34120Secreted arabinogalactan oligomer endo-hydrolase; Hydrolyzes the beta-1,4-galactan linkages of arabinogalactan type I, a pectic substance found in plants such as soybeans.
ganA protein networkhttps://string-db.org/network/224308.BSU34130Arabinogalactan type I oligomer exo-hydrolase (beta-galactosidase, lactase); Hydrolyzes oligosaccharides released by the endo-1,4-beta- galactosidase GalA from arabinogalactan type I, a pectic pl [...]
ganQ protein networkhttps://string-db.org/network/224308.BSU34140Arabinogalactan oligomer permease; Could be part of a binding-protein-dependent transport system for arabinogalactan oligomers; probably responsible for the translocation of the substrate across [...]
ganP protein networkhttps://string-db.org/network/224308.BSU34150Arabinogalactan oligomer permease; Could be part of a binding-protein-dependent transport system for arabinogalactan oligomers; probably responsible for the translocation of the substrate across [...]
cycB protein networkhttps://string-db.org/network/224308.BSU34160Cyclodextrin-binding lipoprotein; Binding protein for cyclodextrin; involved in its cellular uptake. Interacts with all natural cyclodextrins: alpha, beta and gamma; Belongs to the bacterial solu [...]
ganR protein networkhttps://string-db.org/network/224308.BSU34170Transcriptional regulator (LacI family); Negatively regulates expression of ganA.
yvfI protein networkhttps://string-db.org/network/224308.BSU34180Putative transcriptional regulator (GntR family); Negatively regulates the transcription of the lutABC operon, which is required for L-lactate utilization. LutR activity is regulated by lactate, [...]
yvfH protein networkhttps://string-db.org/network/224308.BSU34190Putative lactate permease; Is the principal permease for the uptake of L-lactate in B.subtilis.
sigL protein networkhttps://string-db.org/network/224308.BSU34200RNA polymerase sigma-54 factor (sigma-L); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor [...]
yvfG protein networkhttps://string-db.org/network/224308.BSU34210Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
epsO protein networkhttps://string-db.org/network/224308.BSU34220Putative pyruvyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion [...]
epsN protein networkhttps://string-db.org/network/224308.BSU34230Putative aminotransferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of [...]
epsM protein networkhttps://string-db.org/network/224308.BSU34240Putative O-acetyltransferase; Catalyzes the conversion of UDP-2,4,6-trideoxy-2-acetamido-4- amino glucose to UDP-2,4,6-trideoxy-2,4-diacetamido glucose, commonly known as UDP-N,N'-diacetylbacillo [...]
epsL protein networkhttps://string-db.org/network/224308.BSU34250Putative phosphotransferase involved in extracellular matrix synthesis; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm forma [...]
epsK protein networkhttps://string-db.org/network/224308.BSU34265Putative extracellular matrix component exporter; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsib [...]
epsJ protein networkhttps://string-db.org/network/224308.BSU34280Putative glycosyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion [...]
epsI protein networkhttps://string-db.org/network/224308.BSU34290Putative polysaccharide pyruvyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible fo [...]
epsH protein networkhttps://string-db.org/network/224308.BSU34300Putative glycosyltransferase involved in biofilm formation; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is [...]
epsG protein networkhttps://string-db.org/network/224308.BSU34310Biofilm extracellular matrix formation enzyme; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible [...]
epsF protein networkhttps://string-db.org/network/224308.BSU34320Putative glycosyltransferase involved in extracellular matrix formation; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm form [...]
epsE protein networkhttps://string-db.org/network/224308.BSU34330Bifunctional flagellar clutch and glycosyltransferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is resp [...]
epsD protein networkhttps://string-db.org/network/224308.BSU34340Putative extracellular matrix biosynthesis enzyme; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsi [...]
epsC protein networkhttps://string-db.org/network/224308.BSU34350Putative UDP-sugar epimerase; Involved in biofilm formation; Belongs to the polysaccharide synthase family.
epsB protein networkhttps://string-db.org/network/224308.BSU34360Protein tyrosine kinase; Evidence 2b: Function of strongly homologous gene; enzyme; Belongs to the CpsD/CapB family.
epsA protein networkhttps://string-db.org/network/224308.BSU34370Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator.
slrR protein networkhttps://string-db.org/network/224308.BSU34380Transcriptional regulator of autolysin genes; Represses sigma(D)-dependent flagellar genes and activate the eps and yqxM operons. Repressor activity is regulated by SlrA. Controls the initiation [...]
pnbA protein networkhttps://string-db.org/network/224308.BSU34390Para-nitrobenzyl esterase (intracellular esterase B); Catalyzes hydrolysis of several beta-lactam antibiotic PNB esters to the corresponding free acid and PNB alcohol; Belongs to the type-B carbo [...]
padC protein networkhttps://string-db.org/network/224308.BSU34400Phenolic acid decarboxylase; Involved in the decarboxylation and detoxification of phenolic derivatives. It is able to catalyze the decarboxylation of ferulic, p-coumaric and caffeic acids; Belon [...]
yveG protein networkhttps://string-db.org/network/224308.BSU34410Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0311 family.
yveF protein networkhttps://string-db.org/network/224308.BSU34420Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
racX protein networkhttps://string-db.org/network/224308.BSU34430Amino acid racemase; Amino-acid racemase able to utilize a broad range of substrates. Preferentially catalyzes the epimerization of LL- diaminopimelate, as well as the racemization of D-lysine, L [...]
pbpE protein networkhttps://string-db.org/network/224308.BSU34440Penicillin-binding protein 4*; Probably involved in peptidoglycan modification during cortex synthesis.
sacB protein networkhttps://string-db.org/network/224308.BSU34450Levansucrase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
levB protein networkhttps://string-db.org/network/224308.BSU34460Endolevanase; Catalyzes the degradation of levan mainly into levanbiose (difructose). Is not active on sucrose; Belongs to the glycosyl hydrolase 32 family.
yveA protein networkhttps://string-db.org/network/224308.BSU34470L-aspartate/L-glutamate permease; Uptake of L-aspartate with the concomitant import of a proton. Can also transport aspartate hydroxamate and L-glutamate with lower affinity and efficiency.
yvdT protein networkhttps://string-db.org/network/224308.BSU34480Putative transcriptional regulator (TetR/AcrR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: puta [...]
yvdS protein networkhttps://string-db.org/network/224308.BSU34490Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
yvdR protein networkhttps://string-db.org/network/224308.BSU34500Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
yvdQ protein networkhttps://string-db.org/network/224308.BSU34510Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yvdP protein networkhttps://string-db.org/network/224308.BSU34520Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
cotR protein networkhttps://string-db.org/network/224308.BSU34530Spore coat protein assembly factor CotR; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
clpP protein networkhttps://string-db.org/network/224308.BSU34540ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a limited peptidase activity in the absence of ATP-binding subu [...]
mdxM protein networkhttps://string-db.org/network/224308.BSU34550Beta-phosphoglucomutase; Catalyzes the interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), and forming beta-D-glucose 1,6- (bis)phosphate (beta-G16P) as an intermediat [...]
mdxL protein networkhttps://string-db.org/network/224308.BSU34560Oligo-1,4-1,6-alpha-glucosidase (sucrase-maltase-isomaltase); Hydrolyzes various disaccharides such as sucrose, maltose, and isomaltose with different efficiencies. Also hydrolyzes longer maltode [...]
mdxK protein networkhttps://string-db.org/network/224308.BSU34570Maltose phosphorylase; Catalyzes the phosphorolysis of maltose, leading to the formation of glucose and glucose 1-P.
mdxJ protein networkhttps://string-db.org/network/224308.BSU34580Putative component of maltodextrin transporter; Could have a role in maltodextrin utilization.
mdxG protein networkhttps://string-db.org/network/224308.BSU34590Maltodextrin ABC transporter (permease); Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Prob [...]
mdxF protein networkhttps://string-db.org/network/224308.BSU34600Maltodextrin ABC transport system (permease); Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane [...]
mdxE protein networkhttps://string-db.org/network/224308.BSU34610Maltose/maltodextrin-binding lipoprotein; Part of the ABC transporter complex involved in maltodextrin import. Binds maltodextrin. Can also bind maltose with low affinity, but is not involved in [...]
mdxD protein networkhttps://string-db.org/network/224308.BSU34620Maltogenic alpha-amylase; Hydrolyzes beta-cyclodextrin to maltose and glucose, soluble starch to maltose and glucose, and pullulan to panose with trace amounts of maltose and glucose. It is also [...]
mdxR protein networkhttps://string-db.org/network/224308.BSU34630Transcriptional activator of the maltodextrin operon (LacI family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type pr: putative regulator.
yvdD protein networkhttps://string-db.org/network/224308.BSU34640Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the LOG family.
yvdC protein networkhttps://string-db.org/network/224308.BSU34650Putative pyrophosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yvdB protein networkhttps://string-db.org/network/224308.BSU34660Putative anion transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yvdA protein networkhttps://string-db.org/network/224308.BSU34670Putative carbonic anhydrase; Reversible hydration of carbon dioxide.
yvcT protein networkhttps://string-db.org/network/224308.BSU34680Putative 2-hydroxyacid dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yvcS protein networkhttps://string-db.org/network/224308.BSU34690Putative ABC transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yvcR protein networkhttps://string-db.org/network/224308.BSU34700Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belong [...]
yvcQ protein networkhttps://string-db.org/network/224308.BSU34710Two-component sensor histidine kinase [YvcP]; Member of the two-component regulatory system YvcQ/YvcP. Probably activates YvcP by phosphorylation.
yvcP protein networkhttps://string-db.org/network/224308.BSU34720Two-component response regulator [YvcQ]; Member of the two-component regulatory system YvcQ/YvcP.
yvzJ protein networkhttps://string-db.org/network/224308.BSU34729Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
yvcN protein networkhttps://string-db.org/network/224308.BSU34730Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the arylamine N-acet [...]
crh protein networkhttps://string-db.org/network/224308.BSU34740Catabolite repression HPr-like protein; Along with seryl-phosphorylated HPr, phosphorylated Crh is implicated in carbon catabolite repression (CCR) of levanase, inositol dehydrogenase, and beta-x [...]
whiA protein networkhttps://string-db.org/network/224308.BSU34750Putative morphogen; Involved in cell division and chromosome segregation. May influence the activity of FtsZ. Binds DNA, but does not seem to function as a transcription factor ; Belongs to the W [...]
mgfK protein networkhttps://string-db.org/network/224308.BSU34760Gluconeogenesis morphogenetic factor; Required for morphogenesis under gluconeogenic growth conditions. Required, in gluconeogenic growth conditions, for the correct localization of PBP1 and henc [...]
yvcJ protein networkhttps://string-db.org/network/224308.BSU34770GTPase; Displays ATPase and GTPase activities. Can also hydrolyze pNPP. May affect the expression of competence via the phosphorylation of a cellular component.
yvcI protein networkhttps://string-db.org/network/224308.BSU34780Putative triphosphate pyrophosphate hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enz [...]
trxB protein networkhttps://string-db.org/network/224308.BSU34790Thioredoxin reductase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [...]
cwlO protein networkhttps://string-db.org/network/224308.BSU34800Secreted cell wall DL-endopeptidase; The C-terminal part of CwlO shows a cell wall hydrolytic DL- endopeptidase activity; Belongs to the peptidase C40 family.
yvcD protein networkhttps://string-db.org/network/224308.BSU34810Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
bmrA protein networkhttps://string-db.org/network/224308.BSU34820Efflux transporter (ATP-binding and permease protein); An efflux transporter able to transport Hoechst 33342, ethidium bromide, doxorubicin and a number of other drugs in vitro into inside out ve [...]
yvzA protein networkhttps://string-db.org/network/224308.BSU34830Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yvcB protein networkhttps://string-db.org/network/224308.BSU34840Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yvcA protein networkhttps://string-db.org/network/224308.BSU34850Putative lipoprotein; Required for complex colony architecture.
hisI protein networkhttps://string-db.org/network/224308.BSU34860phosphoribosyl-AMP cyclohydrolase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; In the C-terminal section; belongs to the PRA [...]
hisF protein networkhttps://string-db.org/network/224308.BSU34870Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces [...]
hisA protein networkhttps://string-db.org/network/224308.BSU34880Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
hisH protein networkhttps://string-db.org/network/224308.BSU34890Amidotransferase (glutaminase); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia a [...]
hisB protein networkhttps://string-db.org/network/224308.BSU34900Imidazoleglycerol-phosphate dehydratase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
hisD protein networkhttps://string-db.org/network/224308.BSU34910Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisG protein networkhttps://string-db.org/network/224308.BSU34920ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
hisZ protein networkhttps://string-db.org/network/224308.BSU34930histidyl-tRNA synthetase-like component of ATP phophoribosyltransferase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase [...]
yvpB protein networkhttps://string-db.org/network/224308.BSU34940Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
pelC protein networkhttps://string-db.org/network/224308.BSU34950Secreted pectate lyase; Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majori [...]
yvoF protein networkhttps://string-db.org/network/224308.BSU34960Putative O-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
ppaX protein networkhttps://string-db.org/network/224308.BSU34970P-Ser-HPr phosphatase; Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool; Belongs to the HAD-like [...]
yvoD protein networkhttps://string-db.org/network/224308.BSU34980Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
lgt protein networkhttps://string-db.org/network/224308.BSU34990Prelipoprotein diacylglycerol transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
hprK protein networkhttps://string-db.org/network/224308.BSU35000Serine/threonine protein kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of 'Ser-45' in HPr, a phosphocarrier protein of the phosphoenolpyruvate-de [...]
nagA protein networkhttps://string-db.org/network/224308.BSU35010N-acetylglucosamine-6-phosphate deacetylase; Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides. Catalyzes the hydrolysis of the N-acetyl group of N-acetylglucosa [...]
nagBA protein networkhttps://string-db.org/network/224308.BSU35020N-acetylglucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to [...]
nagR protein networkhttps://string-db.org/network/224308.BSU35030Transcriptional regulator (GntR family); Main transcriptional repressor of genes involved in N- acetylglucosamine (GlcNAc) transport and utilization. Represses the expression of the nagAB and nag [...]
yvnB protein networkhttps://string-db.org/network/224308.BSU35040Putative exported phosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yvnA protein networkhttps://string-db.org/network/224308.BSU35050Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
cypX protein networkhttps://string-db.org/network/224308.BSU35060cyclo-L-leucyl-L-leucyl dipeptide oxidase; Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. Catalyzes the oxidation of cyclo(L-Leu-L-Leu) (cLL) to yield pulcherriminic a [...]
yvmC protein networkhttps://string-db.org/network/224308.BSU35070Cyclodipeptide synthase; Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to cataly [...]
yvmB protein networkhttps://string-db.org/network/224308.BSU35080Putative transcriptional regulator; Represses the expression of the yvmC-cypX operon, which is involved in pulcherriminic acid biosynthesis. Also negatively regulates yvmA, yvnB and its own expre [...]
yvmA protein networkhttps://string-db.org/network/224308.BSU35090Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yvlD protein networkhttps://string-db.org/network/224308.BSU35100Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yvlC protein networkhttps://string-db.org/network/224308.BSU35110Putative regulator (stress mediated); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
yvlB protein networkhttps://string-db.org/network/224308.BSU35120Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yvlA protein networkhttps://string-db.org/network/224308.BSU35130Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yvkN protein networkhttps://string-db.org/network/224308.BSU35140Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yvzB protein networkhttps://string-db.org/network/224308.BSU35150Putative flagellin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure; Belongs to the bacterial flagellin f [...]
uvrA protein networkhttps://string-db.org/network/224308.BSU35160Excinuclease ABC (subunit A); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed [...]
uvrB protein networkhttps://string-db.org/network/224308.BSU35170Excinuclease ABC (subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for a [...]
csbA protein networkhttps://string-db.org/network/224308.BSU35180Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
yvkC protein networkhttps://string-db.org/network/224308.BSU35190Putative phosphotransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to th [...]
yvkB protein networkhttps://string-db.org/network/224308.BSU35200Putative transcriptional regulator (TetR/AcrR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: puta [...]
yvkA protein networkhttps://string-db.org/network/224308.BSU35210Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
minJ protein networkhttps://string-db.org/network/224308.BSU35220Topological determinant of cell division; The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division, thereby ensuring that division occurs only [...]
ctpB protein networkhttps://string-db.org/network/224308.BSU35240Swarming motility protein; Involved in the signal transduction pathway leading to the proteolytic activation of the mother cell transcription factor pro- sigma-K during sporulation. The signaling [...]
ftsX protein networkhttps://string-db.org/network/224308.BSU35250Cell-division ABC transporter; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. May act as an importer, possibly at the top o [...]
ftsE protein networkhttps://string-db.org/network/224308.BSU35260Cell-division ABC transporter (ATP-binding protein); Part of the ABC transporter FtsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to th [...]
cccB protein networkhttps://string-db.org/network/224308.BSU35270Cytochrome c551; Electron carrier protein.
yvjA protein networkhttps://string-db.org/network/224308.BSU35280Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
prfB protein networkhttps://string-db.org/network/224308.BSU35290Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
secA protein networkhttps://string-db.org/network/224308.BSU35300Translocase binding subunit (ATPase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to [...]
hpf protein networkhttps://string-db.org/network/224308.BSU35310Ribosome-associated sigma 54 modulation protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometim [...]
yvzG protein networkhttps://string-db.org/network/224308.BSU35319Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
fliT protein networkhttps://string-db.org/network/224308.BSU35320Flagellar assembly protein FliT involved in control of flagella expression; May act as an export chaperone for the filament capping protein FliD; Belongs to the bacillales FliT family.
fliS protein networkhttps://string-db.org/network/224308.BSU35330Flagellar assembly protein FliS; Essential for filament assembly. May act as a facilitator of flagellin (hag) secretion. Antagonizes translational repressor CsrA indirectly. Belongs to the FliS f [...]
fliD protein networkhttps://string-db.org/network/224308.BSU35340Flagellar hook-associated capping protein 2 (HAP2); Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the [...]
yvyC protein networkhttps://string-db.org/network/224308.BSU35350Putative flagellar protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.
hag protein networkhttps://string-db.org/network/224308.BSU35360Flagellin protein; Flagellin is the subunit which polymerizes to form the filaments of bacterial flagella. Assembly into flagella requires FliW. Acts as a homeostatic autoinhibitory regulator to [...]
csrA protein networkhttps://string-db.org/network/224308.BSU35370Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence p [...]
fliW protein networkhttps://string-db.org/network/224308.BSU35380Assembly factor of the flagellum; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin (hag), wh [...]
yviE protein networkhttps://string-db.org/network/224308.BSU35390Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535.
flgL protein networkhttps://string-db.org/network/224308.BSU35400Flagellar hook-filament junction; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; structure.
flgK protein networkhttps://string-db.org/network/224308.BSU35410Flagellar hook-filament junction; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; structure.
yvyG protein networkhttps://string-db.org/network/224308.BSU35420Putative flagellar protein; May be involved in the assembly, structure, or function of the flagellum. May polymerize to form a filamentous structure that is part of the flagellum.
flgM protein networkhttps://string-db.org/network/224308.BSU35430Anti-sigma factor repressor of sigma(D)-dependent transcription; Allows the coupling of early and late flagellar synthesis through the repression of RNA polymerase sigma-D factor-dependent transc [...]
yvyF protein networkhttps://string-db.org/network/224308.BSU35440Putative regulator of flagella formation; May be involved in the assembly, structure, or function of the flagellum. May polymerize to form a filamentous structure that is part of the flagellum.
comFC protein networkhttps://string-db.org/network/224308.BSU35450Putative component of the DNA transport apparatus; Involved in transformation (competence for DNA uptake).
comFB protein networkhttps://string-db.org/network/224308.BSU35460Conserved hypothetical protein; Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16009133, 8045879, 8412657.
comFA protein networkhttps://string-db.org/network/224308.BSU35470Helicase competence protein; Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqu [...]
yviA protein networkhttps://string-db.org/network/224308.BSU35480Conserved hypothetical protein; Binds long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
degU protein networkhttps://string-db.org/network/224308.BSU35490Two-component response regulator; Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase. Involved in the control of expression of d [...]
degS protein networkhttps://string-db.org/network/224308.BSU35500Two-component sensor histidine kinase; Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase. Involved in the control of expression [...]
yvyE protein networkhttps://string-db.org/network/224308.BSU35510Putative translation regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator; Belongs [...]
yvhJ protein networkhttps://string-db.org/network/224308.BSU35520Putative membrane bound transcriptional regulator; May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linke [...]
tagO protein networkhttps://string-db.org/network/224308.BSU35530UDP-N-acetylglucosamine:undecaprenyl-P N-acetylglucosaminyl-1-P transferase; Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polyme [...]
tuaH protein networkhttps://string-db.org/network/224308.BSU35540Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
tuaG protein networkhttps://string-db.org/network/224308.BSU35550Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
tuaF protein networkhttps://string-db.org/network/224308.BSU35560Putative hydrolase involved in teichuronic acid synthesis; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: [...]
tuaE protein networkhttps://string-db.org/network/224308.BSU35570Putative polymerase of teichuronic acid repeating units; Might be involved in the polymerization of teichuronic acid repeating units after their translocation to the outer surface of the membrane [...]
tuaD protein networkhttps://string-db.org/network/224308.BSU35580UDP-glucose 6-dehydrogenase; Catalyzes the conversion of UDP-glucose into UDP-glucuronate, one of the precursors of teichuronic acid; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
tuaC protein networkhttps://string-db.org/network/224308.BSU35590Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
tuaB protein networkhttps://string-db.org/network/224308.BSU35600Putative exporter involved in biosynthesis of teichuronic acid; Might be involved in the translocation of teichuronic acid repeating units from the inner to the outer surface of the membrane.
lytC protein networkhttps://string-db.org/network/224308.BSU35620Putative undecaprenyl-phosphate N-acetylgalactosaminyl-1-phosphate transferase; Autolysins are cell wall hydrolases involved in some important biological processes such as cell separation, cell-w [...]
lytB protein networkhttps://string-db.org/network/224308.BSU35630Modifier protein of major autolysin LytC; Possibly involved in cell wall metabolism during spore formation. Enhances the amidase activity approximately threefold.
lytA protein networkhttps://string-db.org/network/224308.BSU35640Membrane bound lipoprotein; Possible role in the secretion of LytB and LytC.
lytR protein networkhttps://string-db.org/network/224308.BSU35650Membrane-bound transcriptional regulator; May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precurs [...]
mnaA protein networkhttps://string-db.org/network/224308.BSU35660UDP-N-acetylmannosamine 2-epimerase; Catalyzes the conversion of UDP-N-acetylglucosamine into UDP- N-acetylmannosamine, a precursor of the teichoic acid linkage unit.
gtaB protein networkhttps://string-db.org/network/224308.BSU35670UTP-glucose-1-phosphate uridylyltransferase; Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycero [...]
ggaB protein networkhttps://string-db.org/network/224308.BSU35680Putative teichoic acid translocation permease protein tagG (fragment); Involved in the biosynthesis of galactosamine-containing minor teichoic acid, a non-essential cell wall polymer in B.subtili [...]
ggaA protein networkhttps://string-db.org/network/224308.BSU35690Poly(glucosyl N-acetylgalactosamine 1-phosphate) glucosyltransferase; Involved in the biosynthesis of galactosamine-containing minor teichoic acid, a non-essential cell wall polymer in B.subtilis [...]
tagH protein networkhttps://string-db.org/network/224308.BSU35700Teichoic acids export ATP-binding protein TagH; Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system.
tagG protein networkhttps://string-db.org/network/224308.BSU35710Teichoic acid precursors permease; Part of the ABC transporter complex TagGH (TC 3.A.1.34.1) involved in exporting the two types of intracellularly synthesized teichoic acids. Probably responsibl [...]
tagF protein networkhttps://string-db.org/network/224308.BSU35720Teichoic acid poly(glycerol phosphate) polymerase; Responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of glycerol phosphate units from CDP-glyc [...]
tagE protein networkhttps://string-db.org/network/224308.BSU35730UDP-glucose:polyglycerol phosphate alpha-glucosyltransferase; Catalyzes the addition of glucose to the C-2 hydroxy group of the glycerol units in teichoic acid.
tagD protein networkhttps://string-db.org/network/224308.BSU35740Glycerol-3-phosphate cytidylyltransferase; Catalyzes the transfer of the cytidylyl group of CTP to sn- glycerol 3-phosphate so the activated glycerol 3-phosphate can be used for teichoic acid syn [...]
tagA protein networkhttps://string-db.org/network/224308.BSU35750N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid [...]
tagB protein networkhttps://string-db.org/network/224308.BSU35760Teichoic acid glycerol-phosphate primase; Catalyzes the addition of a single glycerol phosphate residue to the prenoldiphosphate-linked disaccharide, as a primer for polymerisation by TagF; Belon [...]
tagC protein networkhttps://string-db.org/network/224308.BSU35770Putative polyglycerol phosphate assembly and export protein (teichoic acid biosynthesis); Unknown. Might be involved in poly(glycerol phosphate) teichoic acid biosynthesis.
lytD protein networkhttps://string-db.org/network/224308.BSU35780Exported N-acetylglucosaminidase (major autolysin) (CWBP90); Cell wall hydrolase not involved in cell autolysis, competence, sporulation or germination. It hydrolyzes the beta-1,4 glycan bond bet [...]
yvyI protein networkhttps://string-db.org/network/224308.BSU35790Putative phosphohexomutase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e: enzyme; Belongs to the mannose-6 [...]
gerBA protein networkhttps://string-db.org/network/224308.BSU35800Component of germinant receptor B; Involved in the response to the germinative mixture of L- asparagine, glucose, fructose and potassium ions (AGFK). Cannot stimulate germination in the absence o [...]
gerBB protein networkhttps://string-db.org/network/224308.BSU35810Component of germinant receptor B; Involved in the response to the germinative mixture of L- asparagine, glucose, fructose and potassium ions (AGFK). Could be an amino acid transporter. Cannot st [...]
gerBC protein networkhttps://string-db.org/network/224308.BSU35820Lipoprotein component of the germination receptor B; Involved in the response to the germinative mixture of L- asparagine, glucose, fructose and potassium ions (AGFK). Cannot stimulate germinatio [...]
ywtG protein networkhttps://string-db.org/network/224308.BSU35830Putative carbohydrate transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ywtF protein networkhttps://string-db.org/network/224308.BSU35840Putative transcriptional regulator; May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to [...]
ywtE protein networkhttps://string-db.org/network/224308.BSU35850Putative hydrolase; Catalyzes the dephosphorylation of the riboflavin precursor 5-amino-6-(5-phospho-D-ribitylamino)uracil and of flavin mononucleotide (FMN) in vitro. Also catalyzes the dephosph [...]
pgdS protein networkhttps://string-db.org/network/224308.BSU35860gamma-DD-glutamyl hydrolase (PGA depolymerase); Cleaves, in an endo-type manner, the gamma-glutamyl bond between D-glutamate and L-glutamate of poly-gamma-glutamate (PGA).
capE protein networkhttps://string-db.org/network/224308.BSU35870Factor required for polyglutamate synthesis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
capA protein networkhttps://string-db.org/network/224308.BSU35880Capsular polyglutamate synthetase; Seems to be required for maximum PGA (gamma-polyglutamic acid) production; Belongs to the CapA family.
capC protein networkhttps://string-db.org/network/224308.BSU35890Capsular polyglutamate amide ligase/translocase subunit; Required for PGA (gamma-polyglutamic acid) biosynthesis.
capB protein networkhttps://string-db.org/network/224308.BSU35900Capsular polyglutamate synthetase (ATP-dependent amide ligase); Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for [...]
rbsR protein networkhttps://string-db.org/network/224308.BSU35910Transcriptional regulator (LacI family); Transcriptional repressor for the ribose rbsDACBK operon.
rbsK protein networkhttps://string-db.org/network/224308.BSU35920Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histi [...]
rbsD protein networkhttps://string-db.org/network/224308.BSU35930Ribose ABC transporter (membrane bound ribose binding); Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
rbsA protein networkhttps://string-db.org/network/224308.BSU35940Ribose ABC transporter (ATP-binding protein); Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC tra [...]
rbsC protein networkhttps://string-db.org/network/224308.BSU35950Ribose ABC transporter (permease); Part of the ABC transporter complex RbsABC involved in ribose import. Probably responsible for the translocation of the substrate across the membrane.
rbsB protein networkhttps://string-db.org/network/224308.BSU35960Ribose ABC transporter (ribose-binding lipoprotein); Part of the ABC transporter complex RbsABC involved in ribose import. Binds ribose.
ywsB protein networkhttps://string-db.org/network/224308.BSU35970Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15187182.
ywsA protein networkhttps://string-db.org/network/224308.BSU35980Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 11782522.
ywrO protein networkhttps://string-db.org/network/224308.BSU35990Nitroreductase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
alsD protein networkhttps://string-db.org/network/224308.BSU36000Alpha-acetolactate decarboxylase; Converts acetolactate into acetoin, which can be excreted by the cells. This may be a mechanism for controlling the internal pH of cells in the stationary stage; [...]
alsS protein networkhttps://string-db.org/network/224308.BSU36010Alpha-acetolactate synthase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
alsR protein networkhttps://string-db.org/network/224308.BSU36020Transcriptional regulator controlling alsSD and ictEP expression (LysR family); Regulates the expression of the alsSD operon for acetoin biosynthesis.
ywrK protein networkhttps://string-db.org/network/224308.BSU36030Putative Na+/H+ antiporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ywrJ protein networkhttps://string-db.org/network/224308.BSU36040Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 14762006.
cotB protein networkhttps://string-db.org/network/224308.BSU36050Spore coat protein (outer); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
cotH protein networkhttps://string-db.org/network/224308.BSU36060Spore coat protein (inner); Involved in the assembly of several proteins in the inner and outer layer of the spore coat. Stabilizes CotC and CotU in the mother cell compartment of sporulating cel [...]
cotG protein networkhttps://string-db.org/network/224308.BSU36070Spore morphogenetic protein; May be a morphogenetic protein that is required for the incorporation of protein CotB into the spore coat.
ywrF protein networkhttps://string-db.org/network/224308.BSU36080Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ywrE protein networkhttps://string-db.org/network/224308.BSU36090Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ywrD protein networkhttps://string-db.org/network/224308.BSU36100Putative enzyme; Overexpressed protein with an N-terminal His tag has been reported not to hydrolyze glutathione; it is not clear if the construct is processed to 2 subunits.
ywrC protein networkhttps://string-db.org/network/224308.BSU36110Putative transcriptional regulator (Lrp/AsnC family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putat [...]
ywrB protein networkhttps://string-db.org/network/224308.BSU36120Putative anion transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ywrA protein networkhttps://string-db.org/network/224308.BSU36130Putative anion transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ywqO protein networkhttps://string-db.org/network/224308.BSU36140Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ywqN protein networkhttps://string-db.org/network/224308.BSU36150Putative oxidoreductase; Putative NADPH-dependent oxidoreductase; Belongs to the SsuE family.
ywqM protein networkhttps://string-db.org/network/224308.BSU36160Putative transcriptional regulator (LysR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
ywqL protein networkhttps://string-db.org/network/224308.BSU36170Putative deoxyribonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving [...]
rttO protein networkhttps://string-db.org/network/224308.BSU36180Putative ribonuclease antitoxin; Probable antitoxin component of a type II toxin-antitoxin (TA) system. Probably neutralizes the ability to inhibit growth of cognate toxin YwqJ. Probably does not [...]
rttN protein networkhttps://string-db.org/network/224308.BSU36190Putative ribonuclease toxin; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus may have RNase activity and probably inhibits growth. Its toxic effects are probably [...]
ywqI protein networkhttps://string-db.org/network/224308.BSU36200Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ywqH protein networkhttps://string-db.org/network/224308.BSU36210Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15101989.
ywqG protein networkhttps://string-db.org/network/224308.BSU36220Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ywqF protein networkhttps://string-db.org/network/224308.BSU36230UDP-glucose dehydrogenase; Catalyzes the conversion of UDP-glucose into UDP-glucuronate, one of the precursors of teichuronic acid. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
ywqE protein networkhttps://string-db.org/network/224308.BSU36240Protein tyrosine-phosphatase; Dephosphorylates the phosphotyrosine-containing proteins YwqD, YwqF and Ssb.
ptkA protein networkhttps://string-db.org/network/224308.BSU36250Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenas [...]
ywqC protein networkhttps://string-db.org/network/224308.BSU36260Modulator of YwqD protein tyrosine kinase activity; Required for YwqD kinase activity. May bring YwqD and its substrates into contact. Probably involved in the regulation of capsular polysacchari [...]
ywzD protein networkhttps://string-db.org/network/224308.BSU36269Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 20709900.
ywqB protein networkhttps://string-db.org/network/224308.BSU36270Putative replication initiation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
hepA protein networkhttps://string-db.org/network/224308.BSU36280ATPase involved in RNA remodelling DNA recombination and repair; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor; Belongs to the [...]
ywpJ protein networkhttps://string-db.org/network/224308.BSU36290Putative phosphatase; Catalyzes the dephosphorylation of phosphorylated 5-6 carbon sugars and monophosphate nucleotides (NMP) in vitro (By similarity). To a lesser extent, dephosphorylates flavin [...]
glcR protein networkhttps://string-db.org/network/224308.BSU36300Transcriptional regulator (DeoR family); Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by othe [...]
ssbB protein networkhttps://string-db.org/network/224308.BSU36310Single-strand DNA-binding protein; Not essential for replication of the chromosome, but is required for optimal competence. Binds ssDNA, binding is facilitated by DprA, acts as an accessory facto [...]
ywpG protein networkhttps://string-db.org/network/224308.BSU36320Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ywpF protein networkhttps://string-db.org/network/224308.BSU36330Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ywpE protein networkhttps://string-db.org/network/224308.BSU36340Putative sortase; Seems not to play a major role if any as a sortase.
ywpD protein networkhttps://string-db.org/network/224308.BSU36350Putative two-component sensor histidine kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
mscL protein networkhttps://string-db.org/network/224308.BSU36360Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. Forms a nonselective ion channel with a conductance of about 4 [...]
fabZ protein networkhttps://string-db.org/network/224308.BSU36370(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated [...]
rapD protein networkhttps://string-db.org/network/224308.BSU36380Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; Belongs to the RAP family.
flhP protein networkhttps://string-db.org/network/224308.BSU36390Putative flagellar hook-basal body protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative struct [...]
flhO protein networkhttps://string-db.org/network/224308.BSU36400Putative flagellar basal-body rod protein; Not required for motility.
mbl protein networkhttps://string-db.org/network/224308.BSU36410MreB-like morphogen; Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. [...]
spoIIID protein networkhttps://string-db.org/network/224308.BSU36420Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K).
usd protein networkhttps://string-db.org/network/224308.BSU36430Putative factor required for translation of spoIIID; Required for translation of SpoIIID.
ywoH protein networkhttps://string-db.org/network/224308.BSU36440Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
ywoG protein networkhttps://string-db.org/network/224308.BSU36450Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ywoF protein networkhttps://string-db.org/network/224308.BSU36460Putative pectate lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
pucI protein networkhttps://string-db.org/network/224308.BSU36470Allantoin permease; Transport of allantoin.
ywoD protein networkhttps://string-db.org/network/224308.BSU36480Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ywoC protein networkhttps://string-db.org/network/224308.BSU36490Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the isochor [...]
ywoB protein networkhttps://string-db.org/network/224308.BSU36500Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
amtB protein networkhttps://string-db.org/network/224308.BSU36510Ammonium transporter; Functions as an ammonium and methylammonium transporter in the absence of glutamine. Required for ammonium utilization at low concentrations or at low pH values, when ammoni [...]
glnK protein networkhttps://string-db.org/network/224308.BSU36520Nitrogen-regulated PII-like regulator protein; Required for full induction of the nrgAB operon under conditions of ammonium limitation.
bcrC protein networkhttps://string-db.org/network/224308.BSU36530Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the BcrC/YbjG family.
ywnJ protein networkhttps://string-db.org/network/224308.BSU36540Putative integral inner membrane protein; May be important for peptidoglycan remodeling.
spoIIQ protein networkhttps://string-db.org/network/224308.BSU36550Forespore protein required for alternative engulfment; Involved in forespore engulfment and required for anchoring membrane proteins on the forespore side of the septal membrane. Forms a channel [...]
ywnH protein networkhttps://string-db.org/network/224308.BSU36560Putative phosphinothricin acetyltransferase; This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Inactivates PTT by transfer of an acetyl group (By similarity [...]
ywnG protein networkhttps://string-db.org/network/224308.BSU36570Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ywnF protein networkhttps://string-db.org/network/224308.BSU36580Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
clsA protein networkhttps://string-db.org/network/224308.BSU36590Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belong [...]
mta protein networkhttps://string-db.org/network/224308.BSU36600Transcriptional regulator (MerR family); Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the [...]
ywnC protein networkhttps://string-db.org/network/224308.BSU36610Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ywnB protein networkhttps://string-db.org/network/224308.BSU36620Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ywnA protein networkhttps://string-db.org/network/224308.BSU36630Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ureC protein networkhttps://string-db.org/network/224308.BSU36640Urease (alpha subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subu [...]
ureB protein networkhttps://string-db.org/network/224308.BSU36650Urease (beta subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the urease beta subunit family.
ureA protein networkhttps://string-db.org/network/224308.BSU36660Urease (gamma subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the urease gamma subunit family.
csbD protein networkhttps://string-db.org/network/224308.BSU36670Conserved hypothetical protein; Evidence 7: Gene remnant.
ywmF protein networkhttps://string-db.org/network/224308.BSU36680Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane compo [...]
rapB protein networkhttps://string-db.org/network/224308.BSU36690Response regulator aspartate phosphatase; Prevents sporulation by dephosphorylating Spo0F.
moaA protein networkhttps://string-db.org/network/224308.BSU36700Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate (By similarity). Required for both nitrate assimilation and r [...]
fdhD protein networkhttps://string-db.org/network/224308.BSU36710Putative subunit of an respiration oxidoreductase; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor p [...]
ywmE protein networkhttps://string-db.org/network/224308.BSU36720Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
ywmD protein networkhttps://string-db.org/network/224308.BSU36730Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; To B.subtilis Y [...]
ywmC protein networkhttps://string-db.org/network/224308.BSU36740Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; To B.subtilis Y [...]
spoIID protein networkhttps://string-db.org/network/224308.BSU36750Autolysin required for complete dissolution of the asymmetric septum (stage II sporulation); May act at the level of sigma-G activity or its stability. SpoIID is probably required for engulfment.
murAA protein networkhttps://string-db.org/network/224308.BSU36760UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine. Essential for cell growth; Belongs to the EPSP synthase family. MurA subfamil [...]
ywmB protein networkhttps://string-db.org/network/224308.BSU36770Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ywzB protein networkhttps://string-db.org/network/224308.BSU36780Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ywmA protein networkhttps://string-db.org/network/224308.BSU36790Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
atpC protein networkhttps://string-db.org/network/224308.BSU36800ATP synthase (subunit epsilon, F1 subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane.
atpD protein networkhttps://string-db.org/network/224308.BSU36810ATP synthase (subunit beta, component F1); Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs t [...]
atpG protein networkhttps://string-db.org/network/224308.BSU36820ATP synthase (subunit gamma, component F1); Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activi [...]
atpA protein networkhttps://string-db.org/network/224308.BSU36830ATP synthase (subunit alpha, component F1); Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit; Belongs to the ATPase alpha/be [...]
atpH protein networkhttps://string-db.org/network/224308.BSU36840ATP synthase (subunit delta, component F1); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) cont [...]
atpF protein networkhttps://string-db.org/network/224308.BSU36850ATP synthase (subunit b, component F0); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containi [...]
atpE protein networkhttps://string-db.org/network/224308.BSU36860ATP synthase (subunit c, component F0); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containi [...]
atpB protein networkhttps://string-db.org/network/224308.BSU36870ATP synthase (subunit a, component F0); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
atpI protein networkhttps://string-db.org/network/224308.BSU36880ATP synthase (subunit i); A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex; Belongs to the bacterial AtpI family.
upp protein networkhttps://string-db.org/network/224308.BSU36890Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
glyA protein networkhttps://string-db.org/network/224308.BSU36900Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
ywlG protein networkhttps://string-db.org/network/224308.BSU36910Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15995210.
ywlF protein networkhttps://string-db.org/network/224308.BSU36920Ribose 5-phosphate epimerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
ywlE protein networkhttps://string-db.org/network/224308.BSU36930Protein-tyrosine-phosphatase; Catalyzes the specific dephosphorylation of phosphoarginine residues in a large number of proteins. Counteracts the protein arginine kinase McsB in vivo. Can dephosp [...]
ywlD protein networkhttps://string-db.org/network/224308.BSU36940Putative integral inner membrane protein UPF0059 DUF0204 family; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.
tsaC protein networkhttps://string-db.org/network/224308.BSU36950tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with a [...]
ywlB protein networkhttps://string-db.org/network/224308.BSU36960Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
spoIIR protein networkhttps://string-db.org/network/224308.BSU36970pro-sigma(E) endopeptidase (stage II sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
ywlA protein networkhttps://string-db.org/network/224308.BSU36980Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ywkF protein networkhttps://string-db.org/network/224308.BSU36990Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
prmC protein networkhttps://string-db.org/network/224308.BSU37000Glutamine methylase of release factor 1 (and perhaps others) at a GGQ site; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the un [...]
prfA protein networkhttps://string-db.org/network/224308.BSU37010Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
ywkD protein networkhttps://string-db.org/network/224308.BSU37020Putative lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
racA protein networkhttps://string-db.org/network/224308.BSU37030Chromosome-anchoring protein RacA; Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segre [...]
ywkB protein networkhttps://string-db.org/network/224308.BSU37040Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
maeA protein networkhttps://string-db.org/network/224308.BSU37050NAD-dependent malic enzyme (conversion of malate into pyruvate); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
tdk protein networkhttps://string-db.org/network/224308.BSU37060Thymidine kinase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
rpmEA protein networkhttps://string-db.org/network/224308.BSU37070Ribosomal protein L31; Binds the 23S rRNA.
rho protein networkhttps://string-db.org/network/224308.BSU37080Transcriptional terminator Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release [...]
BSU37089 protein networkhttps://string-db.org/network/224308.BSU37089Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 20525796.
ywjI protein networkhttps://string-db.org/network/224308.BSU37090Putative fructose 1,6-bisphosphatase class II; Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtili [...]
murAB protein networkhttps://string-db.org/network/224308.BSU37100UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
ywjH protein networkhttps://string-db.org/network/224308.BSU37110Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Does not show fructose-6-P aldolase activity.
fbaA protein networkhttps://string-db.org/network/224308.BSU37120Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphos [...]
spo0F protein networkhttps://string-db.org/network/224308.BSU37130Two-component response regulator; Key element in the phosphorelay regulating sporulation initiation. Phosphorylation of spo0B during sporulation initiation.
ywjG protein networkhttps://string-db.org/network/224308.BSU37140Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
pyrG protein networkhttps://string-db.org/network/224308.BSU37150CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the [...]
rpoE protein networkhttps://string-db.org/network/224308.BSU37160RNA polymerase (delta subunit); Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcri [...]
acdA protein networkhttps://string-db.org/network/224308.BSU37170acyl-CoA dehydrogenase; Involved in the degradation of long-chain fatty acids.
fadF protein networkhttps://string-db.org/network/224308.BSU37180Putative iron-sulphur-binding reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
clsB protein networkhttps://string-db.org/network/224308.BSU37190Cardiolipin synthetase; Involved in the biosynthesis of cardiolipin.
ywjD protein networkhttps://string-db.org/network/224308.BSU37200Putative UV damage repair endonuclease; Component in a DNA repair pathway. Removal of UV LIGHT damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to [...]
ywjC protein networkhttps://string-db.org/network/224308.BSU37210Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ywjB protein networkhttps://string-db.org/network/224308.BSU37220Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
ywjA protein networkhttps://string-db.org/network/224308.BSU37230Putative ABC lipid transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putat [...]
ywiE protein networkhttps://string-db.org/network/224308.BSU37240Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By s [...]
narI protein networkhttps://string-db.org/network/224308.BSU37250Nitrate reductase (gamma subunit); The gamma chain is a membrane-embedded heme-iron unit resembling cytochrome b, which transfers electrons from quinones to the beta subunit.
narJ protein networkhttps://string-db.org/network/224308.BSU37260Nitrate reductase molybdenum cofactor assembly chaperone NarJ; Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase. [...]
narH protein networkhttps://string-db.org/network/224308.BSU37270Nitrate reductase (beta subunit); The beta chain is an electron transfer unit containing four cysteine clusters involved in the formation of iron-sulfur centers. Electrons are transferred from th [...]
narG protein networkhttps://string-db.org/network/224308.BSU37280Nitrate reductase (alpha subunit); The alpha chain is the actual site of nitrate reduction.
arfM protein networkhttps://string-db.org/network/224308.BSU37290Transcriptional regulator; Activates, in anaerobic conditions, the transcription of the fermentative operons lctEP and alsDS, of the hmp gene encoding a flavohemoglobin-like protein, the nitrite [...]
ywiC protein networkhttps://string-db.org/network/224308.BSU37300Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
fnr protein networkhttps://string-db.org/network/224308.BSU37310Transcriptional regulator (FNR/CAP family); It is involved in the activation of genes necessary for anaerobic respiration.
narK protein networkhttps://string-db.org/network/224308.BSU37320Nitrite extrusion permease; Involved in excretion of nitrite produced by the dissimilatory reduction of nitrate; Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) [...]
argS protein networkhttps://string-db.org/network/224308.BSU37330arginyl-tRNA synthetase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
ywiB protein networkhttps://string-db.org/network/224308.BSU37340Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
sboA protein networkhttps://string-db.org/network/224308.BSU37350Subtilosin A; Has bacteriocidal activity against some Gram-positive bacteria such as Listeria, some species of Bacillus and E.faecium. A single mutation (Thr-14-Ile) confers hemolytic activity ag [...]
sboX protein networkhttps://string-db.org/network/224308.BSU37360Putative bacteriocin-like product; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
albA protein networkhttps://string-db.org/network/224308.BSU37370Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether [...]
albB protein networkhttps://string-db.org/network/224308.BSU37380Putative membrane component involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for maximal production and for optimal immunity to subtilosin.
albC protein networkhttps://string-db.org/network/224308.BSU37390Putative transporter involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin; Belongs to the ABC transporter superfamily.
albD protein networkhttps://string-db.org/network/224308.BSU37400Putative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin.
albE protein networkhttps://string-db.org/network/224308.BSU37410Putative hydrolase involved in subtilosin production; Involved in the production of the bacteriocin subtilosin.
albF protein networkhttps://string-db.org/network/224308.BSU37420Putative peptidase involved in subtilosin production; Required for production of the bacteriocin subtilosin. Could catalyze some step in the processing of presubtilosin.
albG protein networkhttps://string-db.org/network/224308.BSU37430Putative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin.
ywhL protein networkhttps://string-db.org/network/224308.BSU37440Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ywhK protein networkhttps://string-db.org/network/224308.BSU37450Factor interacting with DNA helicase PcrA; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
rapF protein networkhttps://string-db.org/network/224308.BSU37460Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
phrF protein networkhttps://string-db.org/network/224308.BSU37470Secreted regulator of the activity of phosphatase RapF; Inhibitor of the activity of phosphatase RapF; Belongs to the phr family.
ywhH protein networkhttps://string-db.org/network/224308.BSU37480Putative RNA-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
speB protein networkhttps://string-db.org/network/224308.BSU37490Agmatinase; Catalyzes the formation of putrescine from agmatine; Belongs to the arginase family. Agmatinase subfamily.
speE protein networkhttps://string-db.org/network/224308.BSU37500Spermidine synthase; Involved in the cell growth and proliferation. Catalyzes the irreversible transfer of a propylamine group from the amino donor S- adenosylmethioninamine (decarboxy-AdoMet) to [...]
pbpG protein networkhttps://string-db.org/network/224308.BSU37510Sporulation specific penicillin-binding protein; Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first laye [...]
ywhD protein networkhttps://string-db.org/network/224308.BSU37520Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ywhC protein networkhttps://string-db.org/network/224308.BSU37530Putative metal-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belong [...]
ywhB protein networkhttps://string-db.org/network/224308.BSU375401,3-keto-enol tautomerase; Catalyzes both 1,3- and 1,5-keto-enol tautomerization of the diacid 2-hydroxymuconate (2-hydroxy-2,4-hexadienedioate) to produce 2- oxo-4-hexenedioate. This reaction is [...]
ywhA protein networkhttps://string-db.org/network/224308.BSU37550Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
thrZ protein networkhttps://string-db.org/network/224308.BSU37560threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor en [...]
mmr protein networkhttps://string-db.org/network/224308.BSU37570Toxic compound efflux transporter; Resistance to the epoxide antibiotic methylenomycin; Belongs to the major facilitator superfamily. EmrB family.
ywgB protein networkhttps://string-db.org/network/224308.BSU37580Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
ywgA protein networkhttps://string-db.org/network/224308.BSU37590Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855250.
ywfO protein networkhttps://string-db.org/network/224308.BSU37600Putative metal-dependent phosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
ywzC protein networkhttps://string-db.org/network/224308.BSU37610Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855250; Belongs to the UPF0741 family.
rsfA protein networkhttps://string-db.org/network/224308.BSU37620Prespore-specific regulatory gene; Seems to improve the efficiency of sporulation by fine-tuning the expression of genes in the sigma F regulon, particularly the timing of their expression. Negat [...]
ywfM protein networkhttps://string-db.org/network/224308.BSU37630Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
lipL protein networkhttps://string-db.org/network/224308.BSU37640Octanoyl-[GcvH]:protein N-octanoyltransferase; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent e [...]
cysL protein networkhttps://string-db.org/network/224308.BSU37650Regulator of sulfur assimilation CysL, activates cysJI expression; Transcriptional activator of the cysJI operon which is involved in sulfur assimilation. Also negatively regulates its own transc [...]
pta protein networkhttps://string-db.org/network/224308.BSU37660Phosphotransacetylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
hemQ protein networkhttps://string-db.org/network/224308.BSU37670Essential component of heme biosynthesis; May function as heme-dependent peroxidase.
bacH protein networkhttps://string-db.org/network/224308.BSU37680Cyclohexenol-containing tetrahydro-4-hydroxyphenylpyruvate H(4)HPP in bacilysin synthesis; Along with the bacABCDEF operon, BacG is involved in the biosynthesis of the nonribosomally synthesized [...]
bacG protein networkhttps://string-db.org/network/224308.BSU37690Phenylalanine aminotransferase forming tetrahydrotyrosine in bacilysin synthesis; Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibio [...]
bacE protein networkhttps://string-db.org/network/224308.BSU37700Efflux protein for bacilysin excretion, self-protection against bacilysin; Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this [...]
bacD protein networkhttps://string-db.org/network/224308.BSU37710Alanine-anticapsin ligase; Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes [...]
bacC protein networkhttps://string-db.org/network/224308.BSU37720Bacilysin biosynthesis oxidoreductase; Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase [...]
bacB protein networkhttps://string-db.org/network/224308.BSU37730Isomerase component of bacilysin (l-alanine-[2,3-epoxycyclohexano-4]-l-alanine) synthetase; Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipepti [...]
bacA protein networkhttps://string-db.org/network/224308.BSU37740Bacilysin biosynthesis protein, dehydratase; Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine [...]
ywfA protein networkhttps://string-db.org/network/224308.BSU37750Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
rocC protein networkhttps://string-db.org/network/224308.BSU37760Arginine/ornithine permease; Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine.
rocB protein networkhttps://string-db.org/network/224308.BSU37770Putative N-deacylase involved in arginine and ornithine utilization; Involved in arginine degradative pathway.
rocA protein networkhttps://string-db.org/network/224308.BSU37780Delta-1-pyrroline-5 carboxylate dehydrogenase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
rocG protein networkhttps://string-db.org/network/224308.BSU37790Glutamate dehydrogenase; Devoted to catabolic function of glutamate (and other amino acids of the glutamate family) utilization as sole nitrogen source. It is not involved in anabolic function of [...]
yweA protein networkhttps://string-db.org/network/224308.BSU37800Member of the processed secretome; Has a minor role in biofilm architecture. May contribute to the surface hydrophobicity.
spsL protein networkhttps://string-db.org/network/224308.BSU37810dTDP-4-deoxyrhamnose-3,5-epimerase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
spsK protein networkhttps://string-db.org/network/224308.BSU37820Putative dTDP-4-dehydrorhamnose reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
spsJ protein networkhttps://string-db.org/network/224308.BSU37830dTDP-glucose 4,6-dehydratase; Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6- deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction.
spsI protein networkhttps://string-db.org/network/224308.BSU37840Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymid [...]
spsG protein networkhttps://string-db.org/network/224308.BSU37850Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To M.jannasc [...]
spsF protein networkhttps://string-db.org/network/224308.BSU37860Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
spsE protein networkhttps://string-db.org/network/224308.BSU37870Putative phosphoenolpyruvate-sugar pyruvyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
spsD protein networkhttps://string-db.org/network/224308.BSU37880Putative TDP-glycosamine N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzy [...]
spsC protein networkhttps://string-db.org/network/224308.BSU37890Putative glutamine-dependent sugar transaminase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to [...]
spsB protein networkhttps://string-db.org/network/224308.BSU37900Putative dTDP glycosyl/glycerophosphate transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putati [...]
spsA protein networkhttps://string-db.org/network/224308.BSU37910Spore coat dTDP-glycosyltransferase; Glycosyltransferase implicated in the synthesis of the spore coat; Belongs to the glycosyltransferase 2 family.
gerQ protein networkhttps://string-db.org/network/224308.BSU37920Inner spore coat protein; Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is d [...]
ywdK protein networkhttps://string-db.org/network/224308.BSU37930Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0382 family.
ywdJ protein networkhttps://string-db.org/network/224308.BSU37940Putative purine/pyrimidine permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; [...]
ywdI protein networkhttps://string-db.org/network/224308.BSU37950Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ywdH protein networkhttps://string-db.org/network/224308.BSU37960Putative aldehyde dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ung protein networkhttps://string-db.org/network/224308.BSU37970uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the u [...]
ywdF protein networkhttps://string-db.org/network/224308.BSU37980Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to t [...]
ywdE protein networkhttps://string-db.org/network/224308.BSU37990Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ywdD protein networkhttps://string-db.org/network/224308.BSU38000Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ywzG protein networkhttps://string-db.org/network/224308.BSU38018Putative transcriptional regulator, PadR family; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative r [...]
pdxK protein networkhttps://string-db.org/network/224308.BSU38020Pyridoxine, pyridoxal, and pyridoxamine kinase; Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates. Can also use hydroxymethylp [...]
ywdA protein networkhttps://string-db.org/network/224308.BSU38030Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
sacA protein networkhttps://string-db.org/network/224308.BSU38040Sucrase-6-phosphate hydrolase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; Belongs to the glycosyl hydrolase 32 family.
sacP protein networkhttps://string-db.org/network/224308.BSU38050Phosphotransferase system (PTS) sucrose-specific enzyme IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport syste [...]
ywcJ protein networkhttps://string-db.org/network/224308.BSU38060Formate/nitrite transporter; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t: transporter.
sacT protein networkhttps://string-db.org/network/224308.BSU38070Transcriptional antiterminator; Mediates positive regulation of the sacPA operon by functioning as an antiterminator factor of transcription; Belongs to the transcriptional antiterminator BglG fa [...]
ywcI protein networkhttps://string-db.org/network/224308.BSU38080Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
vpr protein networkhttps://string-db.org/network/224308.BSU38090Extracellular serine protease; Not required for growth or sporulation.
ywcH protein networkhttps://string-db.org/network/224308.BSU38100Putative monooxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To bacterial alkan [...]
nfrAA protein networkhttps://string-db.org/network/224308.BSU38110FMN-containing NADPH-linked nitro/flavin reductase; Reduces FMNH(2) to FMN, with NADPH as reductant. It also reduces nitroaromatic compounds, quinones and azo dyes.
rodA protein networkhttps://string-db.org/network/224308.BSU38120Factor involved in extension of the lateral walls of the cell; Peptidoglycan polymerase that is essential for cell wall elongation. Also required for the maintenance of the rod cell shape. Belong [...]
ywcE protein networkhttps://string-db.org/network/224308.BSU38130Protein required for proper spore morphogenesis and germination; Required for proper spore morphogenesis. Important for spore germination; Belongs to the YwcE family.
qoxD protein networkhttps://string-db.org/network/224308.BSU38140Cytochrome aa3-600 quinol oxidase (subunit IV); Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth (By si [...]
qoxC protein networkhttps://string-db.org/network/224308.BSU38150Cytochrome aa3-600 quinol oxidase (subunit III); Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth (By s [...]
qoxB protein networkhttps://string-db.org/network/224308.BSU38160Cytochrome aa3-600 quinol oxidase (subunit I); Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth (By sim [...]
qoxA protein networkhttps://string-db.org/network/224308.BSU38170Cytochrome aa3-600 quinol oxidase (subunit II); Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Subun [...]
ywzA protein networkhttps://string-db.org/network/224308.BSU38180Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
galT protein networkhttps://string-db.org/network/224308.BSU38190Galactose-1-phosphate uridyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
galK protein networkhttps://string-db.org/network/224308.BSU38200Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
ywcD protein networkhttps://string-db.org/network/224308.BSU38210Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ywcC protein networkhttps://string-db.org/network/224308.BSU38220Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
slrA protein networkhttps://string-db.org/network/224308.BSU38229Anti-repressor of SlrR; Required specifically for induction of eps and yqxM operons by antagonizing SinR. Regulates SlrR activity. Controls the initiation of biofilm formation.
ywcB protein networkhttps://string-db.org/network/224308.BSU38230Putative phage protein (superinfection immunity); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachrom [...]
ywcA protein networkhttps://string-db.org/network/224308.BSU38240Putative acetate Na+-dependent symporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transpor [...]
ywbO protein networkhttps://string-db.org/network/224308.BSU38250Putative sulfur oxido-reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
efeN protein networkhttps://string-db.org/network/224308.BSU38260Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity).
efeM protein networkhttps://string-db.org/network/224308.BSU38270Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family.
efeU protein networkhttps://string-db.org/network/224308.BSU38280Ferrous ion permease; Uptake of Fe(2+) ions across the membrane.
thiE protein networkhttps://string-db.org/network/224308.BSU38290Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamin [...]
thiM protein networkhttps://string-db.org/network/224308.BSU38300Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ).
ywbI protein networkhttps://string-db.org/network/224308.BSU38310Putative transcriptional regulator (LysR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
cidA protein networkhttps://string-db.org/network/224308.BSU38320Holin regulator of murein hydrolases; Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins Lrg [...]
ywbG protein networkhttps://string-db.org/network/224308.BSU38330Anti-holin factor controlling activity of murein hydrolases; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; regulator.
ywbF protein networkhttps://string-db.org/network/224308.BSU38340Putative sugar permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
ywbE protein networkhttps://string-db.org/network/224308.BSU38350Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ywbD protein networkhttps://string-db.org/network/224308.BSU38360Putative AdoMet-dependent methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzym [...]
ywbC protein networkhttps://string-db.org/network/224308.BSU38370Putative lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glyoxalase [...]
ywbB protein networkhttps://string-db.org/network/224308.BSU38380Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
ywbA protein networkhttps://string-db.org/network/224308.BSU38390Putative phosphotransferase system enzyme IIC permease component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes [...]
epr protein networkhttps://string-db.org/network/224308.BSU38400Extracellular serine protease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the peptidase S8 family.
sacX protein networkhttps://string-db.org/network/224308.BSU38410Negative regulator of SacY; Negatively regulates SacY activity by catalyzing its phosphorylation on 'His-99'. Negatively regulates SacY.
sacY protein networkhttps://string-db.org/network/224308.BSU38420Transcriptional antiterminator; In the presence of sucrose, SacY is activated and prevents premature termination of transcription by binding to a RNA- antiterminator (RAT) sequence (partially ove [...]
gspA protein networkhttps://string-db.org/network/224308.BSU38430Putative glycosyl transferase (general stress protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
ywaF protein networkhttps://string-db.org/network/224308.BSU38440Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
ywaE protein networkhttps://string-db.org/network/224308.BSU38450Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
tyrZ protein networkhttps://string-db.org/network/224308.BSU38460tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
ywaD protein networkhttps://string-db.org/network/224308.BSU38470Double-zinc aminopeptidase; Catalyzes the hydrolysis of a range of N-terminal amino acids.
relQ protein networkhttps://string-db.org/network/224308.BSU38480(p)ppGpp synthetase; Functions as a (p)ppGpp synthase; GDP can be used instead of GTP, resulting in an increase of (p)ppGpp synthesis. Overexpression in relA mutants (triple relA-yjbM-ywaC deleti [...]
menA protein networkhttps://string-db.org/network/224308.BSU384901,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
ywzH protein networkhttps://string-db.org/network/224308.BSU38499Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
dltA protein networkhttps://string-db.org/network/224308.BSU38500D-alanine:D-alanyl-carrier protein ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protei [...]
dltB protein networkhttps://string-db.org/network/224308.BSU38510Putative D-alanine esterase for lipoteichoic acid and wall teichoic acid; Involved in the D-alanylation of lipoteichoic acid (LTA). Could be involved in the transport of activated D-alanine throu [...]
dltC protein networkhttps://string-db.org/network/224308.BSU38520D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier [...]
dltD protein networkhttps://string-db.org/network/224308.BSU38530Putative D-alanine esterase for lipoteichoic acid and wall teichoic acid synthesis; Involved in the D-alanylation of lipoteichoic acid (LTA). Could be responsible for the transfer of DltC-carried [...]
dltE protein networkhttps://string-db.org/network/224308.BSU38540Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the sh [...]
ilvK protein networkhttps://string-db.org/network/224308.BSU38550Branched-chain amino acid aminotransferase; Transaminates branched-chain amino acids and ketoglutarate. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
licH protein networkhttps://string-db.org/network/224308.BSU385606-phospho-beta-glucosidase; Hydrolyzes phospho-beta-glucosides.
licA protein networkhttps://string-db.org/network/224308.BSU38570Phosphotransferase system (PTS) lichenan-specific enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, cat [...]
licC protein networkhttps://string-db.org/network/224308.BSU38580Phosphotransferase system (PTS) lichenan-specific enzyme IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, cat [...]
licB protein networkhttps://string-db.org/network/224308.BSU38590Phosphotransferase system (PTS) lichenan-specific enzyme IIB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport syste [...]
licR protein networkhttps://string-db.org/network/224308.BSU38600Transcriptional activator of the lichenan operon; Positive regulator of the licABCH operon; Belongs to the transcriptional antiterminator BglG family.
yxzF protein networkhttps://string-db.org/network/224308.BSU38610Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
aag protein networkhttps://string-db.org/network/224308.BSU386203-alkylated purines and hypoxanthine DNA glycosidase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the DNA glycosy [...]
katX protein networkhttps://string-db.org/network/224308.BSU38630Major catalase in spores; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; Belongs to the catalase family.
yxlH protein networkhttps://string-db.org/network/224308.BSU38640Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yxlG protein networkhttps://string-db.org/network/224308.BSU38650Putative ABC-transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yxlF protein networkhttps://string-db.org/network/224308.BSU38660Putative ABC transporter component (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: p [...]
yxlE protein networkhttps://string-db.org/network/224308.BSU38670Negative regulator of sigma-Y activity; Together with YxlD is important for negative regulation of sigma Y activity.
yxlD protein networkhttps://string-db.org/network/224308.BSU38680Putative sigma-Y antisigma factor component; Together with YxlE, is important for negative regulation of sigma Y activity, being the major negative regulator.
yxlC protein networkhttps://string-db.org/network/224308.BSU38690sigma-Y antisigma factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
sigY protein networkhttps://string-db.org/network/224308.BSU38700RNA polymerase ECF (extracytoplasmic function)-type sigma factor (sigma-Y); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are [...]
yxlA protein networkhttps://string-db.org/network/224308.BSU38710Putative purine-cytosine permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
nnrA protein networkhttps://string-db.org/network/224308.BSU38720NAD(P)H dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of t [...]
cydD protein networkhttps://string-db.org/network/224308.BSU38730ABC membrane transporter (ATP-binding protein) required for cytochrome bb' function; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport sys [...]
cydC protein networkhttps://string-db.org/network/224308.BSU38740ABC membrane transporter (ATP-binding protein) required for cytochrome bb' function; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport sys [...]
cydB protein networkhttps://string-db.org/network/224308.BSU38750Cytochrome bb' ubiquinol oxidase (subunit II); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
cydA protein networkhttps://string-db.org/network/224308.BSU38760Cytochrome bb' ubiquinol oxidase (subunit I); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the cytochrome ubiquinol oxidase subunit [...]
cimH protein networkhttps://string-db.org/network/224308.BSU38770citrate/malate/H+ symporter; Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate. Appears to be an electroneutral proton-solute symporter; the nu [...]
yxkI protein networkhttps://string-db.org/network/224308.BSU38780Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 fa [...]
yxzE protein networkhttps://string-db.org/network/224308.BSU38790Putative bacteriocin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
yxkH protein networkhttps://string-db.org/network/224308.BSU38800Putative exported polysaccharide deacetylase, lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: [...]
msmX protein networkhttps://string-db.org/network/224308.BSU38810Multiple sugar-binding transporter ATP-binding protein; Part of the ABC transporter complex involved in maltodextrin import (Probable). Is also part of the ABC transporter complex MelEDC- MsmX in [...]
yxkF protein networkhttps://string-db.org/network/224308.BSU38820Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
aldY protein networkhttps://string-db.org/network/224308.BSU38830Putative aldehyde dehydrogenase; May contribute to protect cells against stress due to ethanol and related compounds; Belongs to the aldehyde dehydrogenase family.
yxkD protein networkhttps://string-db.org/network/224308.BSU38840Efflux transporter; Evidence 1a: Function experimentally demonstrated in the studied strain; transporter.
yxkC protein networkhttps://string-db.org/network/224308.BSU38850Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12823818, 15033535.
galE protein networkhttps://string-db.org/network/224308.BSU38860UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reductio [...]
yxkA protein networkhttps://string-db.org/network/224308.BSU38870Putative bacteriophage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
yxjO protein networkhttps://string-db.org/network/224308.BSU38880Putative transcriptional regulator (LysR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belong [...]
yxjN protein networkhttps://string-db.org/network/224308.BSU38890Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yxjM protein networkhttps://string-db.org/network/224308.BSU38900Two-component sensor histidine kinase [YxjL]; Probable member of the two-component regulatory system YxjM/YxjL. May activate YxjL by phosphorylation.
yxjL protein networkhttps://string-db.org/network/224308.BSU38910Two-component response regulator [YxjM]; Probable member of the two-component regulatory system YxjM/YxjL.
pepT protein networkhttps://string-db.org/network/224308.BSU38920Peptidase T (tripeptidase); Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
yxjJ protein networkhttps://string-db.org/network/224308.BSU38930Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yxjI protein networkhttps://string-db.org/network/224308.BSU38940Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the LOR family.
yxjH protein networkhttps://string-db.org/network/224308.BSU38950Putative methyl-tetrahydrofolate methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putativ [...]
yxjG protein networkhttps://string-db.org/network/224308.BSU38960Putative methyltetrahydrofolate methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative [...]
yxjF protein networkhttps://string-db.org/network/224308.BSU38970Putative dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the sho [...]
atoB protein networkhttps://string-db.org/network/224308.BSU38980Acetoacetyl CoA-transferase (subunit B); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the 3-oxoacid CoA-transferas [...]
atoA protein networkhttps://string-db.org/network/224308.BSU38990Acetoacetyl CoA-transferase (subunit A); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the 3-oxoacid CoA-transferas [...]
yxjC protein networkhttps://string-db.org/network/224308.BSU39000Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yxjB protein networkhttps://string-db.org/network/224308.BSU39010Putative ribosomal RNA methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; [...]
nupG protein networkhttps://string-db.org/network/224308.BSU39020Purine nucleoside transporter; Involved in the uptake of the purine ribonucleosides inosine and guanosine.
yxiS protein networkhttps://string-db.org/network/224308.BSU39040Hypothetical protein; Evidence 7: Gene remnant.
katE protein networkhttps://string-db.org/network/224308.BSU39050Catalase 2; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation.
citH protein networkhttps://string-db.org/network/224308.BSU39060Secondary transporter of divalent metal ions/citrate complexes; Transports the free citrate anion. Probably cotransports citrate and at least three or four protons. The citrate uptake is inhibite [...]
bglS protein networkhttps://string-db.org/network/224308.BSU39070Endo-beta-1,3-1,4 glucanase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 16 family.
licT protein networkhttps://string-db.org/network/224308.BSU39080Transcriptional antiterminator (BglG family); Mediates positive regulation of the glucanase operon (licST) by functioning as an antiterminator factor of transcription. Prevents termination at ter [...]
yxiP protein networkhttps://string-db.org/network/224308.BSU39090Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
yxiO protein networkhttps://string-db.org/network/224308.BSU39100Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
deaD protein networkhttps://string-db.org/network/224308.BSU39110ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA h [...]
yxiM protein networkhttps://string-db.org/network/224308.BSU39120Putative esterase (lipoprotein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 'GDSL' lipo [...]
yxzJ protein networkhttps://string-db.org/network/224308.BSU39139Hypothetical protein; Evidence 7: Gene remnant.
yxiK protein networkhttps://string-db.org/network/224308.BSU39140Putative phage head maturation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
yxiJ protein networkhttps://string-db.org/network/224308.BSU39150Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yxiI protein networkhttps://string-db.org/network/224308.BSU39160Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yxzG protein networkhttps://string-db.org/network/224308.BSU39170Putative nucleic acid binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
yxiH protein networkhttps://string-db.org/network/224308.BSU39180Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yxiG protein networkhttps://string-db.org/network/224308.BSU39190Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yxzC protein networkhttps://string-db.org/network/224308.BSU39200Putative nucleic acid binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
yxiF protein networkhttps://string-db.org/network/224308.BSU39210Putative phage reverse transcriptase or polymerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putativ [...]
yxxG protein networkhttps://string-db.org/network/224308.BSU39220Hypothetical protein; Immunity protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. Neutralizes the tRNase activit [...]
wapA protein networkhttps://string-db.org/network/224308.BSU39230Cell wall-associated protein precursor; Toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. A site-specific general [...]
yxxF protein networkhttps://string-db.org/network/224308.BSU39240Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yxiE protein networkhttps://string-db.org/network/224308.BSU39250Phosphate starvation protein (universal stress protein A family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the universal stress [...]
bglH protein networkhttps://string-db.org/network/224308.BSU39260Aryl-phospho-beta-d-glucosidase; Catalyzes the hydrolysis of aryl-phospho-beta-D-glucosides such as 4-methylumbelliferyl-phospho-beta-D-glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. [...]
bglP protein networkhttps://string-db.org/network/224308.BSU39270Phosphotransferase system (PTS) beta-glucoside-specific enzyme IIBCA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transpo [...]
yxxE protein networkhttps://string-db.org/network/224308.BSU39280Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
rtbE protein networkhttps://string-db.org/network/224308.BSU39290Antitoxin factor of the RttD-RttE toxin-antitoxin system; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the RNase activity of cognate toxin YxiD, as well as its abilit [...]
rtbD protein networkhttps://string-db.org/network/224308.BSU39300Ribonuclease toxin of the RtbD-RtbE toxin-antitoxin system; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 409-569) has RNase activity, and inhibits growth upo [...]
yxiC protein networkhttps://string-db.org/network/224308.BSU39310Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yxiB protein networkhttps://string-db.org/network/224308.BSU39320Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
abnB protein networkhttps://string-db.org/network/224308.BSU39330Arabinan endo-1,5-alpha-L-arabinosidase; Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-( [...]
yxzL protein networkhttps://string-db.org/network/224308.BSU39339Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
hutP protein networkhttps://string-db.org/network/224308.BSU39340Transcriptional antiterminator; Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating [...]
hutH protein networkhttps://string-db.org/network/224308.BSU39350Histidine ammonia-lyase (histidase); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
hutU protein networkhttps://string-db.org/network/224308.BSU39360Urocanase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate; Belongs to the urocanase family.
hutI protein networkhttps://string-db.org/network/224308.BSU39370Imidazolone-5-propionate hydrolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
hutG protein networkhttps://string-db.org/network/224308.BSU39380Formiminoglutamate hydrolase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide.
hutM protein networkhttps://string-db.org/network/224308.BSU39390Histidine permease; Evidence 2b: Function of strongly homologous gene; Product type t: transporter.
pdp protein networkhttps://string-db.org/network/224308.BSU39400Pyrimidine-nucleoside phosphorylase; Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribo [...]
nupC protein networkhttps://string-db.org/network/224308.BSU39410Pyrimidine-nucleoside Na+(H+) cotransporter; Transport of the pyrimidine nucleoside uridine.
deoC protein networkhttps://string-db.org/network/224308.BSU39420Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
deoR protein networkhttps://string-db.org/network/224308.BSU39430Transcriptional regulator; Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA, which consists of a palindrome and a direct repeat sequence located 3' to t [...]
yxxB protein networkhttps://string-db.org/network/224308.BSU39440Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yxeR protein networkhttps://string-db.org/network/224308.BSU39450Putative ethanolamine transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yxeQ protein networkhttps://string-db.org/network/224308.BSU39460Putative catabolic enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the [...]
yxeP protein networkhttps://string-db.org/network/224308.BSU39470Putative amidohydrolase; Probably catalyzes the deacetylation of N-acetylcysteine (NAC) to acetate and cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.sub [...]
yxeO protein networkhttps://string-db.org/network/224308.BSU39480Putative ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Responsible for en [...]
yxeN protein networkhttps://string-db.org/network/224308.BSU39490Putative ABC transporter (permease); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Probably responsible for the [...]
yxeM protein networkhttps://string-db.org/network/224308.BSU39500Putative ABC transporter (binding lipoprotein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine; Belongs to the bac [...]
yxeL protein networkhttps://string-db.org/network/224308.BSU39510Putative acetyltransferase; Catalyzes the N-acetylation of S-(2-succino)cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole [...]
yxeK protein networkhttps://string-db.org/network/224308.BSU39520Putative monooxygenase; Probably catalyzes the oxygenation of the 2-position of the succinyl moiety of N-acetyl-S-(2-succino)cysteine, causing a spontaneous elimination reaction of the resulting [...]
yxeJ protein networkhttps://string-db.org/network/224308.BSU39530Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yxeI protein networkhttps://string-db.org/network/224308.BSU39540Penicillin V acylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the peptidase C59 family.
yxeH protein networkhttps://string-db.org/network/224308.BSU39550Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yxeG protein networkhttps://string-db.org/network/224308.BSU39560Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yxeF protein networkhttps://string-db.org/network/224308.BSU39570Lipocalin-like protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
yxeE protein networkhttps://string-db.org/network/224308.BSU39580Inner spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
yxeD protein networkhttps://string-db.org/network/224308.BSU39590Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yxeC protein networkhttps://string-db.org/network/224308.BSU39600Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yxeB protein networkhttps://string-db.org/network/224308.BSU39610ABC transporter (ferrioxamine binding lipoprotein); Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to [...]
yxeA protein networkhttps://string-db.org/network/224308.BSU39620Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yxdM protein networkhttps://string-db.org/network/224308.BSU39630ABC transporter (permease); Part of the ABC transporter complex YxdLM which could be involved in peptide resistance; Belongs to the ABC-4 integral membrane protein family.
yxdL protein networkhttps://string-db.org/network/224308.BSU39640ABC transporter (ATP-binding protein); Part of the ABC transporter complex YxdLM which could be involved in peptide resistance. Responsible for energy coupling to the transport system (Probable).
yxdK protein networkhttps://string-db.org/network/224308.BSU39650Two-component sensor histidine kinase [YxdJ]; Probable member of the two-component regulatory system YxdK/YxdJ. May activate YxdJ in response to the antibacterial protein LL-37.
yxdJ protein networkhttps://string-db.org/network/224308.BSU39660Two-component response regulator [YxdK]; Probable member of the two-component regulatory system YxdK/YxdJ. Positively regulates the expression of the yxdLMyxeA operon by direct interaction with i [...]
iolJ protein networkhttps://string-db.org/network/224308.BSU396702-deoxy-5-keto-D-gluconic acid 6-phosphate aldolase; Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6- phospho-5-dehydro- [...]
iolI protein networkhttps://string-db.org/network/224308.BSU39680Inosose isomerase; Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6/3,5-pentahydroxycyclohexanone) to 1- keto-D-chiro-inositol (1KDCI or 2,3,5/4,6-pentahy [...]
iolH protein networkhttps://string-db.org/network/224308.BSU39690Putative sugar-phosphate epimerase/isomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzy [...]
iolG protein networkhttps://string-db.org/network/224308.BSU39700Myo-inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase; Involved in the oxidation of myo-inositol (MI) and D-chiro- inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D- [...]
iolF protein networkhttps://string-db.org/network/224308.BSU39710Inositol transport protein; Minor myo-inositol uptake transporter. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
iolE protein networkhttps://string-db.org/network/224308.BSU397202-keto-myo-inositol dehydratase; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-dike [...]
iolD protein networkhttps://string-db.org/network/224308.BSU397303D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).
iolC protein networkhttps://string-db.org/network/224308.BSU397402-deoxy-5-keto-D-gluconic acid kinase; Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2- deoxy-D-gluconate (DKGP).
iolB protein networkhttps://string-db.org/network/224308.BSU397505-deoxy-D-glucuronic acid isomerase; Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D-gluconate).
mmsA protein networkhttps://string-db.org/network/224308.BSU39760Methylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
iolR protein networkhttps://string-db.org/network/224308.BSU39770Transcriptional regulator (DeoR family); Iol operon repressor.
iolS protein networkhttps://string-db.org/network/224308.BSU39780Aldo-keto reductase; In vitro, is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose and methylglyoxal in the presence of NADPH, albeit with poor effi [...]
yxcE protein networkhttps://string-db.org/network/224308.BSU39790Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yxcD protein networkhttps://string-db.org/network/224308.BSU39800Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
csbC protein networkhttps://string-db.org/network/224308.BSU39810Putative sugar transporter; Could serve either a nutritional or an osmotic protection function; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
htpG protein networkhttps://string-db.org/network/224308.BSU39820Class III heat-shock protein (molecular chaperone); Molecular chaperone. Has ATPase activity.
yxcA protein networkhttps://string-db.org/network/224308.BSU39830Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yxbG protein networkhttps://string-db.org/network/224308.BSU39840Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the sh [...]
yxbF protein networkhttps://string-db.org/network/224308.BSU39850Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
aldX protein networkhttps://string-db.org/network/224308.BSU39860Putative aldehyde dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs t [...]
yxbD protein networkhttps://string-db.org/network/224308.BSU39870Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yxbC protein networkhttps://string-db.org/network/224308.BSU39880Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yxbB protein networkhttps://string-db.org/network/224308.BSU39890Putative S-adenosylmethionine-dependent methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; [...]
yxbA protein networkhttps://string-db.org/network/224308.BSU39900Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17083466.
yxnB protein networkhttps://string-db.org/network/224308.BSU39910Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
asnH protein networkhttps://string-db.org/network/224308.BSU39920Asparagine synthetase (glutamine-hydrolyzing); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the asparagine synthetase family.
yxaM protein networkhttps://string-db.org/network/224308.BSU39930Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yxaL protein networkhttps://string-db.org/network/224308.BSU39940Membrane associated protein kinase with beta-propeller domain; Increases the processivity of the PcrA helicase, but does not bind to DNA.
yxaJ protein networkhttps://string-db.org/network/224308.BSU39950Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane compo [...]
yxaI protein networkhttps://string-db.org/network/224308.BSU39960Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yxaH protein networkhttps://string-db.org/network/224308.BSU39970Putative integral inner membrane protein; Involved in transport.
qodI protein networkhttps://string-db.org/network/224308.BSU39980Quercetin dioxygenase; Performs the first step in the degradation of the flavonoid quercetin by a dioxygenase reaction. The enzyme catalyzes the cleavage of the O-heteroaromatic ring of the flavo [...]
qdoR protein networkhttps://string-db.org/network/224308.BSU39990Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
yxnA protein networkhttps://string-db.org/network/224308.BSU40000Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the sh [...]
yxaD protein networkhttps://string-db.org/network/224308.BSU40010Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
yxzK protein networkhttps://string-db.org/network/224308.BSU40021Putative integral inner membrane protein involved in export murein hydrolases; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homolog [...]
yxaC protein networkhttps://string-db.org/network/224308.BSU40022Putative murein hydrolase export regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membra [...]
yxaB protein networkhttps://string-db.org/network/224308.BSU40030Putative exopolysaccharide pyruvyl transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative en [...]
glxK protein networkhttps://string-db.org/network/224308.BSU40040Glycerate kinase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
gntR protein networkhttps://string-db.org/network/224308.BSU40050Transcriptional regulator (GntR family); Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to [...]
gntK protein networkhttps://string-db.org/network/224308.BSU40060Gluconate kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
gntP protein networkhttps://string-db.org/network/224308.BSU40070Gluconate permease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter; Belongs to the GntP permease family.
gntZ protein networkhttps://string-db.org/network/224308.BSU40080NAD+-6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH. Does not contrib [...]
ahpC protein networkhttps://string-db.org/network/224308.BSU40090Alkyl hydroperoxide reductase (small subunit); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a [...]
ahpF protein networkhttps://string-db.org/network/224308.BSU40100Alkyl hydroperoxide reductase (large subunit); Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity [...]
bglA protein networkhttps://string-db.org/network/224308.BSU40110Aryl-6-phospho-beta-glucosidase; Catalyzes the hydrolysis of aryl-phospho-beta-D-glucosides such as 4-methylumbelliferyl-phospho-beta-D-glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. [...]
yyzE protein networkhttps://string-db.org/network/224308.BSU40120Putative phosphotransferase system enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phos [...]
yydK protein networkhttps://string-db.org/network/224308.BSU40130Putative transcriptional regulator (GntR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
yyzN protein networkhttps://string-db.org/network/224308.BSU40139Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yydJ protein networkhttps://string-db.org/network/224308.BSU40140Putative permease for export of a regulatory peptide; Suggested to be part of an ABC transporter complex YydIJ involved in export of the modified peptide YydF.
yydI protein networkhttps://string-db.org/network/224308.BSU40150ABC transporter (ATP-binding protein); Suggested to be part of an ABC transporter complex YydIJ involved in export of the modified peptide YydF (Probable). Responsible for energy coupling to the [...]
yydH protein networkhttps://string-db.org/network/224308.BSU40160Putative membrane metalloprotease; Required for production of the modified peptide YydF (Probable). May process the precursor form of YydF to release the active peptide (Potential); Belongs to th [...]
yydG protein networkhttps://string-db.org/network/224308.BSU40170Putative AdoMet radical enzyme; Required for production of the modified peptide YydF (Probable). May activate a metalloenzyme (Potential).
yydF protein networkhttps://string-db.org/network/224308.BSU40180Peptide controlling LiaRS; Suggested to be the precursor for an exported, modified peptide that has antimicrobial and/or signaling properties. Synthesis requires YydG and YydH; the peptide is pro [...]
fbp protein networkhttps://string-db.org/network/224308.BSU40190Fructose-1,6-bisphosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
yydD protein networkhttps://string-db.org/network/224308.BSU40200Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yydC protein networkhttps://string-db.org/network/224308.BSU40210Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yydB protein networkhttps://string-db.org/network/224308.BSU40220Putative phosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the [...]
yydA protein networkhttps://string-db.org/network/224308.BSU40230Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
yyzF protein networkhttps://string-db.org/network/224308.BSU40239Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yycS protein networkhttps://string-db.org/network/224308.BSU40240Putative integrase/transposase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
yycR protein networkhttps://string-db.org/network/224308.BSU40250Putative dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the zin [...]
yyzG protein networkhttps://string-db.org/network/224308.BSU40259Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yycQ protein networkhttps://string-db.org/network/224308.BSU40260Putative conserved membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane comp [...]
yycP protein networkhttps://string-db.org/network/224308.BSU40270Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11557812, 16291680.
yycO protein networkhttps://string-db.org/network/224308.BSU40280Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yycN protein networkhttps://string-db.org/network/224308.BSU40290Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
rapG protein networkhttps://string-db.org/network/224308.BSU40300Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
phrG protein networkhttps://string-db.org/network/224308.BSU40310Secreted regulator of the activity of phosphatase RapG; Inhibitor of the activity of phosphatase RapG.
argI protein networkhttps://string-db.org/network/224308.BSU40320Arginase; Involved in the catabolism of arginine. Belongs to the arginase family.
rocE protein networkhttps://string-db.org/network/224308.BSU40330Arginine/ornithine/gamma-aminobutyrate permease; Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine.
rocD protein networkhttps://string-db.org/network/224308.BSU40340Ornithine aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. Controls arginine catabolism.
rocR protein networkhttps://string-db.org/network/224308.BSU40350Transcriptional regulator (NtrC/NifA family); Positive regulator of arginine catabolism. Controls the transcription of the two operons rocABC and rocDEF and probably acts by binding to the corres [...]
htrC protein networkhttps://string-db.org/network/224308.BSU40360Putative sensor protein; Evidence 7: Gene remnant; Product type pr: putative regulator.
walJ protein networkhttps://string-db.org/network/224308.BSU40370Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the metallo [...]
yycI protein networkhttps://string-db.org/network/224308.BSU40380Regulator of YycFG; Together with YycH, regulates the activity of the two- component system WalR/WalK.
walH protein networkhttps://string-db.org/network/224308.BSU40390Regulator of YycFG; Together with YycI, regulates the activity of the two- component system WalR/WalK.
walK protein networkhttps://string-db.org/network/224308.BSU40400Two-component sensor histidine kinase [YycG]; Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yo [...]
walR protein networkhttps://string-db.org/network/224308.BSU40410Two-component response regulator [YycF]; Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes [...]
purA protein networkhttps://string-db.org/network/224308.BSU40420Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
yycE protein networkhttps://string-db.org/network/224308.BSU40430Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
dnaC protein networkhttps://string-db.org/network/224308.BSU40440Replicative DNA helicase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the helicase family. DnaB subfamily.
yycD protein networkhttps://string-db.org/network/224308.BSU40450Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yyzB protein networkhttps://string-db.org/network/224308.BSU40460Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
yycC protein networkhttps://string-db.org/network/224308.BSU40470Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yycB protein networkhttps://string-db.org/network/224308.BSU40480Putative anion ABC transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transpo [...]
yycA protein networkhttps://string-db.org/network/224308.BSU40490Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
rplI protein networkhttps://string-db.org/network/224308.BSU40500Ribosomal protein L9; Binds to the 23S rRNA.
cdnD protein networkhttps://string-db.org/network/224308.BSU40510Phosphodiesterase acting on cyclic dinucleotides; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP) and to a much lesser extent against cyclic-di-GMP (c-di-GMP) in the DHH/DHH [...]
yybS protein networkhttps://string-db.org/network/224308.BSU40520Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yyzH protein networkhttps://string-db.org/network/224308.BSU40529Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
cotF protein networkhttps://string-db.org/network/224308.BSU40530Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
yybR protein networkhttps://string-db.org/network/224308.BSU40540Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
ppaC protein networkhttps://string-db.org/network/224308.BSU40550Inorganic pyrophosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
yybP protein networkhttps://string-db.org/network/224308.BSU40560Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
yybO protein networkhttps://string-db.org/network/224308.BSU40570Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yybN protein networkhttps://string-db.org/network/224308.BSU40580Conserved hypothetical protein; Evidence 7: Gene remnant.
yybM protein networkhttps://string-db.org/network/224308.BSU40590Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yybL protein networkhttps://string-db.org/network/224308.BSU40600Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yybK protein networkhttps://string-db.org/network/224308.BSU40610Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yybJ protein networkhttps://string-db.org/network/224308.BSU40620Putative ATP-binding cassette protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the ABC t [...]
yybI protein networkhttps://string-db.org/network/224308.BSU40630Inner spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
yybH protein networkhttps://string-db.org/network/224308.BSU40640Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yybG protein networkhttps://string-db.org/network/224308.BSU40650Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11709313.
yybF protein networkhttps://string-db.org/network/224308.BSU40660Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yybE protein networkhttps://string-db.org/network/224308.BSU40670Putative transcriptional regulator (LysR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
yybD protein networkhttps://string-db.org/network/224308.BSU40680Putative acetyltransferase; Could catalyze the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and release both CoA and the acetylated product.
yybC protein networkhttps://string-db.org/network/224308.BSU40690Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane compo [...]
yybB protein networkhttps://string-db.org/network/224308.BSU40700Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yybA protein networkhttps://string-db.org/network/224308.BSU40710Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative [...]
yyaT protein networkhttps://string-db.org/network/224308.BSU40720Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
yyaS protein networkhttps://string-db.org/network/224308.BSU40730Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yyaR protein networkhttps://string-db.org/network/224308.BSU40740Putative acetyl-transferase; Involved in resistance to streptothricin, a broad-spectrum antibiotic produced by streptomycetes. Detoxifies streptothricin via acetylation of the beta amino group of [...]
yyaQ protein networkhttps://string-db.org/network/224308.BSU40750Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yyaP protein networkhttps://string-db.org/network/224308.BSU40760Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
tetB protein networkhttps://string-db.org/network/224308.BSU40770Multifunctional tetracycline-metal/H+ antiporter and Na+(K+)/H+ antiporter; Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the acc [...]
tetL protein networkhttps://string-db.org/network/224308.BSU40780Tetracycline resistance leader peptide; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter.
yyaO protein networkhttps://string-db.org/network/224308.BSU40790Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yyaN protein networkhttps://string-db.org/network/224308.BSU40800Putative transcriptional regulator (MerR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
yyaM protein networkhttps://string-db.org/network/224308.BSU40810Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yyaL protein networkhttps://string-db.org/network/224308.BSU40820Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To C.elegans B0495.5.
yyaK protein networkhttps://string-db.org/network/224308.BSU40830Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
yyaJ protein networkhttps://string-db.org/network/224308.BSU40840Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
maa protein networkhttps://string-db.org/network/224308.BSU40850Maltose O-acetyltransferase; Catalyzes the CoA-dependent transfer of an acetyl group to maltose and other sugars. Acetylates glucose exclusively at the C6 position and maltose at the C6 position [...]
yyaH protein networkhttps://string-db.org/network/224308.BSU40860Putative lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
ccpB protein networkhttps://string-db.org/network/224308.BSU40870Transcriptional repressor of carbon supply (LacI family); Transcriptional regulator involved in catabolite repression of several operons.
exoA protein networkhttps://string-db.org/network/224308.BSU40880Apurinic/apyrimidinic endonuclease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
rpsR protein networkhttps://string-db.org/network/224308.BSU40890Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
ssbA protein networkhttps://string-db.org/network/224308.BSU40900Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of actio [...]
rpsF protein networkhttps://string-db.org/network/224308.BSU40910Ribosomal protein S6 (BS9); Binds together with S18 to 16S ribosomal RNA.
engD protein networkhttps://string-db.org/network/224308.BSU40920Putative GTPase with RNA binding site; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. Belongs to the TRAFAC class OBG-HflX-like GTPas [...]
yyaE protein networkhttps://string-db.org/network/224308.BSU40930Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
yyzM protein networkhttps://string-db.org/network/224308.BSU40939Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
yyaD protein networkhttps://string-db.org/network/224308.BSU40940Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
yyaC protein networkhttps://string-db.org/network/224308.BSU40950Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
parB protein networkhttps://string-db.org/network/224308.BSU40960Site-specific DNA-binding protein; Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition by Soj. It probably interacts with a specif [...]
parA protein networkhttps://string-db.org/network/224308.BSU40970Chromosome partitioning protein; Inhibits the initiation of sporulation, Spo0J antagonizes this inhibition. Soj ultimately inhibits the activation (phosphorylation) of Spo0A; Belongs to the ParA [...]
yyaB protein networkhttps://string-db.org/network/224308.BSU40980Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane [...]
noc protein networkhttps://string-db.org/network/224308.BSU40990DNA-binding protein Spo0J-like; Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, espe [...]
rsmG protein networkhttps://string-db.org/network/224308.BSU410007-methylguanosine methyltransferase (16S rRNA, nucleotide G527); Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
trmF protein networkhttps://string-db.org/network/224308.BSU41010tRNA uridine 5-carboxymethylaminomethyl modification enzyme; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, [...]
mnmE protein networkhttps://string-db.org/network/224308.BSU41020tRNA modification GTPase and tRNA-U34 5-formylation enzyme; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobbl [...]
jag protein networkhttps://string-db.org/network/224308.BSU41030SpoIIIJ-associated RNA/ssDNA-binding protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
oxaAA protein networkhttps://string-db.org/network/224308.BSU41040Sec-independent factor for membrane protein insertion (YidC/SpoIIIJ family); Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membr [...]
rnpA protein networkhttps://string-db.org/network/224308.BSU41050Protein component of ribonuclease P (RNase P) (substrate specificity); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave o [...]
rpmH protein networkhttps://string-db.org/network/224308.BSU41060Ribosomal protein L34; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; structure.