Organism Overview: Blochmannia floridanus


 
gidA protein networkhttps://string-db.org/network/203907.Bfl001Glucose inhibited division protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2) [...]
atpB protein networkhttps://string-db.org/network/203907.Bfl002ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
atpE protein networkhttps://string-db.org/network/203907.Bfl003ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramemb [...]
atpF protein networkhttps://string-db.org/network/203907.Bfl004ATP synthase subunit B; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramemb [...]
atpH protein networkhttps://string-db.org/network/203907.Bfl005ATP synthase delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extra [...]
atpA protein networkhttps://string-db.org/network/203907.Bfl006ATP synthase alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family [...]
atpG protein networkhttps://string-db.org/network/203907.Bfl007ATP synthase gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow [...]
atpD protein networkhttps://string-db.org/network/203907.Bfl008ATP synthase beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alp [...]
atpC protein networkhttps://string-db.org/network/203907.Bfl009ATP synthase epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
glmU protein networkhttps://string-db.org/network/203907.Bfl010UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyz [...]
thdF protein networkhttps://string-db.org/network/203907.Bfl011GTPase for tRNA modification and thiophene and furan oxidation; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the w [...]
yidC protein networkhttps://string-db.org/network/203907.Bfl012Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane [...]
yidD protein networkhttps://string-db.org/network/203907.Bfl013Uncharacterized conserved protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
rnpA protein networkhttps://string-db.org/network/203907.Bfl014RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The p [...]
rpmH protein networkhttps://string-db.org/network/203907.Bfl01550s ribosomal protein l34; COG category=J; Belongs to the bacterial ribosomal protein bL34 family.
dnaN protein networkhttps://string-db.org/network/203907.Bfl016DNA polymerase III beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadin [...]
gyrB protein networkhttps://string-db.org/network/203907.Bfl017DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
ibpA protein networkhttps://string-db.org/network/203907.Bfl018Heat shock protein A; COG category=O; Belongs to the small heat shock protein (HSP20) family.
unknown protein networkhttps://string-db.org/network/203907.Bfl019Probable transmembrane protein; COG category=P.
glyQ protein networkhttps://string-db.org/network/203907.Bfl020glycine-tRNA synthetase, alpha subunit; COG category=J.
glyS protein networkhttps://string-db.org/network/203907.Bfl021glycine-tRNA synthetase, beta subunit; COG category=J.
sodA protein networkhttps://string-db.org/network/203907.Bfl022Manganese superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family [...]
pitA protein networkhttps://string-db.org/network/203907.Bfl024Low-affinity inorganic phosphate transporter; COG category=P.
ubiA protein networkhttps://string-db.org/network/203907.Bfl0254-hydroxybenzoate octaprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ub [...]
zur protein networkhttps://string-db.org/network/203907.Bfl026Zinc uptake regulation protein; COG category=P; Belongs to the Fur family.
dnaB protein networkhttps://string-db.org/network/203907.Bfl027Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
ssb protein networkhttps://string-db.org/network/203907.Bfl028Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of actio [...]
yjcE protein networkhttps://string-db.org/network/203907.Bfl029Sodium/hydrogen exchanger family protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC [...]
gltP protein networkhttps://string-db.org/network/203907.Bfl030Proton glutamate symport protein; Catalyzes the proton-dependent transport of glutamate and aspartate; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP su [...]
yjgF protein networkhttps://string-db.org/network/203907.Bfl031Translation initiation inhibitor; COG category=J.
argI protein networkhttps://string-db.org/network/203907.Bfl032Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
valS protein networkhttps://string-db.org/network/203907.Bfl033valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
holC protein networkhttps://string-db.org/network/203907.Bfl034DNA polymerase III, chi subunit; COG category=L.
pepA protein networkhttps://string-db.org/network/203907.Bfl035Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
yjgP protein networkhttps://string-db.org/network/203907.Bfl036Putative inner membrane protein; COG category=R.
yjgQ protein networkhttps://string-db.org/network/203907.Bfl037Putative inner membrane protein; COG category=R.
yidZ protein networkhttps://string-db.org/network/203907.Bfl038LysR-family transcriptional regulator; COG category=K; Belongs to the LysR transcriptional regulatory family.
unknown-2 protein networkhttps://string-db.org/network/203907.Bfl040Manganese transport system ATP-binding protein; COG category=P.
unknown-3 protein networkhttps://string-db.org/network/203907.Bfl041Manganese transport system permease protein; COG category=P.
yhbG protein networkhttps://string-db.org/network/203907.Bfl042Probable ABC transport protein, ATP-binding component; COG category=R.
yhbN protein networkhttps://string-db.org/network/203907.Bfl043OstA-like protein (organic solvent tolerance); COG category=S.
yrbK protein networkhttps://string-db.org/network/203907.Bfl044Possible exported protein; COG category=S.
yrbA protein networkhttps://string-db.org/network/203907.Bfl045BolA-like protein; COG category=T; Belongs to the BolA/IbaG family.
murA protein networkhttps://string-db.org/network/203907.Bfl046UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
degQ protein networkhttps://string-db.org/network/203907.Bfl047Serine protease; COG category=O; Belongs to the peptidase S1C family.
yhcB protein networkhttps://string-db.org/network/203907.Bfl048Periplasmic membrane protein associated with membrane transport; COG category=R.
rplM protein networkhttps://string-db.org/network/203907.Bfl04950S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the earl [...]
rpsI protein networkhttps://string-db.org/network/203907.Bfl05030S ribosomal subunit protein S9; COG category=J; Belongs to the universal ribosomal protein uS9 family.
yraP protein networkhttps://string-db.org/network/203907.Bfl051Possible lipoprotein; COG category=S.
yraL protein networkhttps://string-db.org/network/203907.Bfl052Tetrapyrrole (Corrin/Porphyrin) Methylases; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
rpoD protein networkhttps://string-db.org/network/203907.Bfl056RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the pri [...]
dnaG protein networkhttps://string-db.org/network/203907.Bfl057DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpsU protein networkhttps://string-db.org/network/203907.Bfl05830S ribosomal subunit protein S21; COG category=J; Belongs to the bacterial ribosomal protein bS21 family.
gcp protein networkhttps://string-db.org/network/203907.Bfl059Possible glycoprotease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer [...]
ygiH protein networkhttps://string-db.org/network/203907.Bfl060Putative inner membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes a [...]
folB protein networkhttps://string-db.org/network/203907.Bfl061Dihydroneopterin aldolase, also has dihydroneopterin triphosphate 2'-epimerase activity; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
cca protein networkhttps://string-db.org/network/203907.Bfl062tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order [...]
rfaE protein networkhttps://string-db.org/network/203907.Bfl063ADP-heptose synthase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-te [...]
yqiC protein networkhttps://string-db.org/network/203907.Bfl064DUF526; COG category=S.
ribB protein networkhttps://string-db.org/network/203907.Bfl0653,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
plsC protein networkhttps://string-db.org/network/203907.Bfl0661-acyl-glycerol-3-phosphate acyltransferase; COG category=I; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
metC protein networkhttps://string-db.org/network/203907.Bfl067Beta-cystathionase; COG category=E.
cutA protein networkhttps://string-db.org/network/203907.Bfl069Periplasmic divalent cation tolerance protein CutA; COG category=P.
mopB protein networkhttps://string-db.org/network/203907.Bfl070GroES protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
mopA protein networkhttps://string-db.org/network/203907.Bfl071GroEL protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
efp protein networkhttps://string-db.org/network/203907.Bfl072Elongation factor P (EF-P); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possi [...]
yjeP protein networkhttps://string-db.org/network/203907.Bfl073Mechanosensitive ion-channel; COG category=M.
psd protein networkhttps://string-db.org/network/203907.Bfl074Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
orn protein networkhttps://string-db.org/network/203907.Bfl075Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
yjeE protein networkhttps://string-db.org/network/203907.Bfl077Putative nucleotide-binding protein; COG category=R.
amiB protein networkhttps://string-db.org/network/203907.Bfl078N-acetylmuramoyl-L-alanine amidase; COG category=M.
miaA protein networkhttps://string-db.org/network/203907.Bfl079tRNA delta-2-isopentenylpyrophosphate (IPP) transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading [...]
hflX protein networkhttps://string-db.org/network/203907.Bfl080HflX protein,putative GTPase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like [...]
hflK protein networkhttps://string-db.org/network/203907.Bfl081HflK protein; HflC and HflK could encode or regulate a protease.
hflC protein networkhttps://string-db.org/network/203907.Bfl082HflC protein; HflC and HflK could regulate a protease.
purA protein networkhttps://string-db.org/network/203907.Bfl083Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
yjfH protein networkhttps://string-db.org/network/203907.Bfl084Probable tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransfera [...]
rpsF protein networkhttps://string-db.org/network/203907.Bfl08530S ribosomal subunit protein S6; Binds together with S18 to 16S ribosomal RNA.
rpsR protein networkhttps://string-db.org/network/203907.Bfl08630S ribosomal subunit protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial [...]
rplI protein networkhttps://string-db.org/network/203907.Bfl08750S ribosomal subunit protein L9; Binds to the 23S rRNA.
cysQ protein networkhttps://string-db.org/network/203907.Bfl088cysQ protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
ytfN protein networkhttps://string-db.org/network/203907.Bfl090Pseudogene of YtfM, putative exported protein; COG category=M.
ppa protein networkhttps://string-db.org/network/203907.Bfl091Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
ispB protein networkhttps://string-db.org/network/203907.Bfl092Octaprenyl-diphosphate synthase; COG category=H; Belongs to the FPP/GGPP synthase family.
rplU protein networkhttps://string-db.org/network/203907.Bfl09350S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
rpmA protein networkhttps://string-db.org/network/203907.Bfl09450S ribosomal subunit protein L27; COG category=J; Belongs to the bacterial ribosomal protein bL27 family.
yhbZ protein networkhttps://string-db.org/network/203907.Bfl095Probable GTP-binding protein; COG category=R.
greA protein networkhttps://string-db.org/network/203907.Bfl096Transcription elongation factor, cleaves 3' nucleotide of paused mRNA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites i [...]
ftsJ protein networkhttps://string-db.org/network/203907.Bfl097Cell division protein 23S rRNA methyltransferase FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal sub [...]
ftsH protein networkhttps://string-db.org/network/203907.Bfl098Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [...]
folP protein networkhttps://string-db.org/network/203907.Bfl099Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate [...]
mrsA protein networkhttps://string-db.org/network/203907.Bfl100PGM/PMM-family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
nusA protein networkhttps://string-db.org/network/203907.Bfl103Transcription pausing; Participates in both transcription termination and antitermination.
infB protein networkhttps://string-db.org/network/203907.Bfl104Protein chain initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to t [...]
rbfA protein networkhttps://string-db.org/network/203907.Bfl105Ribosome-binding factor A (P15B protein); One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal [...]
truB protein networkhttps://string-db.org/network/203907.Bfl106tRNA pseudouridine 5S synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
rpsO protein networkhttps://string-db.org/network/203907.Bfl10730S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridg [...]
pnp protein networkhttps://string-db.org/network/203907.Bfl108Polynucleotide phosphorylase, member of mRNA degradosome; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- directio [...]
deaD protein networkhttps://string-db.org/network/203907.Bfl109Cold-shock DEAD-box protein A, inducible ATP-independent RNA helicase; COG category=L; Belongs to the DEAD box helicase family.
holD protein networkhttps://string-db.org/network/203907.Bfl110DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonu [...]
thrA protein networkhttps://string-db.org/network/203907.Bfl111Aspartokinase I/homoserine dehydrogenase I; COG category=E; In the C-terminal section; belongs to the homoserine dehydrogenase family.
thrB protein networkhttps://string-db.org/network/203907.Bfl112Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
thrC protein networkhttps://string-db.org/network/203907.Bfl113Threonine synthase; COG category=E.
dnaK protein networkhttps://string-db.org/network/203907.Bfl114DnaK protein (heat shock protein 70); Acts as a chaperone; Belongs to the heat shock protein 70 family.
dnaJ protein networkhttps://string-db.org/network/203907.Bfl115DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous [...]
rpsT protein networkhttps://string-db.org/network/203907.Bfl11630S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
ribF protein networkhttps://string-db.org/network/203907.Bfl117Riboflavin biosynthesis protein RibF; COG category=H; Belongs to the ribF family.
ileS protein networkhttps://string-db.org/network/203907.Bfl118isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
lspA protein networkhttps://string-db.org/network/203907.Bfl119Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
dapB protein networkhttps://string-db.org/network/203907.Bfl121Pseudogene of LytB protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
carA protein networkhttps://string-db.org/network/203907.Bfl122Carbamoyl-phosphate synthase small chain; COG category=E; Belongs to the CarA family.
carB protein networkhttps://string-db.org/network/203907.Bfl123Carbamoyl-phosphate synthase large chain; COG category=E.
folA protein networkhttps://string-db.org/network/203907.Bfl124Dihydrofolate reductase type I; COG category=H; Belongs to the dihydrofolate reductase family.
apaH protein networkhttps://string-db.org/network/203907.Bfl125Bis(5'-nucleosyl)-tetraphosphatase; COG category=T.
ksgA protein networkhttps://string-db.org/network/203907.Bfl126Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
pdxA protein networkhttps://string-db.org/network/203907.Bfl127Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously deca [...]
surA protein networkhttps://string-db.org/network/203907.Bfl128Survival protein SurA precursor; COG category=O.
imp protein networkhttps://string-db.org/network/203907.Bfl129Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
leuD protein networkhttps://string-db.org/network/203907.Bfl1303-isopropylmalate dehydratase subunit 1; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD ty [...]
leuC protein networkhttps://string-db.org/network/203907.Bfl1313-isopropylmalate dehydratase subunit 2; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
leuB protein networkhttps://string-db.org/network/203907.Bfl1323-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
leuA protein networkhttps://string-db.org/network/203907.Bfl1332-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isoprop [...]
yabC protein networkhttps://string-db.org/network/203907.Bfl134S-adenosyl methionine adenyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ftsL protein networkhttps://string-db.org/network/203907.Bfl135Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins [...]
ftsI protein networkhttps://string-db.org/network/203907.Bfl136Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
murE protein networkhttps://string-db.org/network/203907.Bfl137UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG [...]
murF protein networkhttps://string-db.org/network/203907.Bfl138UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapepti [...]
mraY protein networkhttps://string-db.org/network/203907.Bfl139phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY su [...]
murD protein networkhttps://string-db.org/network/203907.Bfl140UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDE [...]
ftsW protein networkhttps://string-db.org/network/203907.Bfl141Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
murG protein networkhttps://string-db.org/network/203907.Bfl142Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
murC protein networkhttps://string-db.org/network/203907.Bfl143UDP-N-acetylmuramate:alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
ftsQ protein networkhttps://string-db.org/network/203907.Bfl144Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins [...]
ftsA protein networkhttps://string-db.org/network/203907.Bfl145Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
ftsZ protein networkhttps://string-db.org/network/203907.Bfl146Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
lpxC protein networkhttps://string-db.org/network/203907.Bfl147UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed st [...]
secA protein networkhttps://string-db.org/network/203907.Bfl148Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to [...]
dksA protein networkhttps://string-db.org/network/203907.Bfl149Dosage-dependent dnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulat [...]
folK protein networkhttps://string-db.org/network/203907.Bfl1507, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; COG category=H.
lpdA protein networkhttps://string-db.org/network/203907.Bfl151Dihydrolipoamide dehydrogenase; COG category=C.
aceF protein networkhttps://string-db.org/network/203907.Bfl152Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase; COG category=C.
aceE protein networkhttps://string-db.org/network/203907.Bfl153Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
mrcB protein networkhttps://string-db.org/network/203907.Bfl154Penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domai [...]
yadR protein networkhttps://string-db.org/network/203907.Bfl155HesB-like protein; Required for insertion of 4Fe-4S clusters for at least IspG.
pyrG protein networkhttps://string-db.org/network/203907.Bfl156CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the [...]
eno protein networkhttps://string-db.org/network/203907.Bfl157Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
cysJ protein networkhttps://string-db.org/network/203907.Bfl158Sulfite reductase (NADPH) flavoprotein beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities re [...]
cysI protein networkhttps://string-db.org/network/203907.Bfl159Sulfite reductase (NADPH) hemoprotein alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities re [...]
cysH protein networkhttps://string-db.org/network/203907.Bfl1603'-phosphoadenosine 5'-phosphosulfate sulfotransferase; COG category=E; Belongs to the PAPS reductase family. CysH subfamily.
cysG protein networkhttps://string-db.org/network/203907.Bfl161Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the [...]
cysD protein networkhttps://string-db.org/network/203907.Bfl162ATP sulfurylase (ATP:sulfate adenyltransferase) subunit 2; COG category=E.
cysN protein networkhttps://string-db.org/network/203907.Bfl163ATP sulfurylase (ATP:sulfate adenyltransferase) subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic trans [...]
cysC protein networkhttps://string-db.org/network/203907.Bfl164Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate.
ygbQ protein networkhttps://string-db.org/network/203907.Bfl165Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins [...]
nlpD protein networkhttps://string-db.org/network/203907.Bfl167Pseudogene og YgbP, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; COG category=I.
alaS protein networkhttps://string-db.org/network/203907.Bfl168alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
csrA protein networkhttps://string-db.org/network/203907.Bfl169Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid g [...]
ffh protein networkhttps://string-db.org/network/203907.Bfl1724.5S-RNP protein, GTP binding export factor, part of signal recognition particle with 4.5 RNA; COG category=N.
rpsP protein networkhttps://string-db.org/network/203907.Bfl17330S ribosomal subunit protein S16; COG category=J; Belongs to the bacterial ribosomal protein bS16 family.
rimM protein networkhttps://string-db.org/network/203907.Bfl17416S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Ess [...]
trmD protein networkhttps://string-db.org/network/203907.Bfl175tRNA(guanine-N1)methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rplS protein networkhttps://string-db.org/network/203907.Bfl17650S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
aroF protein networkhttps://string-db.org/network/203907.Bfl177Phospho-2-dehydro-3-deoxyheptonate aldolase, tyr-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptuloson [...]
tyrA protein networkhttps://string-db.org/network/203907.Bfl178Chorismate mutase/prephenate dehydrogenase; COG category=E.
pheA protein networkhttps://string-db.org/network/203907.Bfl179Prephenate dehydratase; COG category=E.
yfiO protein networkhttps://string-db.org/network/203907.Bfl180DNA uptake lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, t [...]
rluD protein networkhttps://string-db.org/network/203907.Bfl181Pseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA); Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; Belongs to the p [...]
clpB protein networkhttps://string-db.org/network/203907.Bfl182ATP-dependent protease, Hsp 100, part of novel multi-chaperone system with DnaK, DnaJ, and GrpE; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from h [...]
murB protein networkhttps://string-db.org/network/203907.Bfl183UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
birA protein networkhttps://string-db.org/network/203907.Bfl184Bifunctional protein: biotin operon repressor and biotin-[acetyl-CoA carboxylase] synthetase; COG category=K.
bfr protein networkhttps://string-db.org/network/203907.Bfl189Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation wit [...]
rpsJ protein networkhttps://string-db.org/network/203907.Bfl19030S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rplC protein networkhttps://string-db.org/network/203907.Bfl19150S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplD protein networkhttps://string-db.org/network/203907.Bfl19250S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. [...]
rplW protein networkhttps://string-db.org/network/203907.Bfl19350S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the m [...]
rplB protein networkhttps://string-db.org/network/203907.Bfl19450S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond format [...]
rpsS protein networkhttps://string-db.org/network/203907.Bfl19530S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplV protein networkhttps://string-db.org/network/203907.Bfl19650S ribosomal subunit protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stag [...]
rpsC protein networkhttps://string-db.org/network/203907.Bfl19730S ribosomal subunit protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 fami [...]
rplP protein networkhttps://string-db.org/network/203907.Bfl19850S ribosomal subunit protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpmC protein networkhttps://string-db.org/network/203907.Bfl19950S ribosomal subunit protein L29; COG category=J.
rpsQ protein networkhttps://string-db.org/network/203907.Bfl20030S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rplN protein networkhttps://string-db.org/network/203907.Bfl20150S ribosomal subunit protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rplX protein networkhttps://string-db.org/network/203907.Bfl20250S ribosomal subunit protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplE protein networkhttps://string-db.org/network/203907.Bfl20350S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central prot [...]
rpsN protein networkhttps://string-db.org/network/203907.Bfl20430S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs t [...]
rpsH protein networkhttps://string-db.org/network/203907.Bfl20530S ribosomal subunit protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Bel [...]
rplF protein networkhttps://string-db.org/network/203907.Bfl20650S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and ne [...]
rplR protein networkhttps://string-db.org/network/203907.Bfl20750S ribosomal subunit protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central p [...]
rpsE protein networkhttps://string-db.org/network/203907.Bfl20830S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
rpmD protein networkhttps://string-db.org/network/203907.Bfl20950S ribosomal subunit protein L30; COG category=J.
rplO protein networkhttps://string-db.org/network/203907.Bfl21050S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
secY protein networkhttps://string-db.org/network/203907.Bfl211Preprotein translocase subunit secY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at t [...]
rpmJ protein networkhttps://string-db.org/network/203907.Bfl21250S ribosomal subunit protein L36; COG category=J; Belongs to the bacterial ribosomal protein bL36 family.
rpsM protein networkhttps://string-db.org/network/203907.Bfl21330S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and pr [...]
rpsK protein networkhttps://string-db.org/network/203907.Bfl21430S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosom [...]
rpsD protein networkhttps://string-db.org/network/203907.Bfl21530S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpoA protein networkhttps://string-db.org/network/203907.Bfl216DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplQ protein networkhttps://string-db.org/network/203907.Bfl21750S ribosomal subunit protein L17; COG category=J.
fmt protein networkhttps://string-db.org/network/203907.Bfl218methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
def protein networkhttps://string-db.org/network/203907.Bfl219Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine i [...]
yrdC protein networkhttps://string-db.org/network/203907.Bfl220Putative translation factor (SUA5); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the c [...]
aroE protein networkhttps://string-db.org/network/203907.Bfl221Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshi [...]
gloB protein networkhttps://string-db.org/network/203907.Bfl223Probable hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
rnhA protein networkhttps://string-db.org/network/203907.Bfl224Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
dnaQ protein networkhttps://string-db.org/network/203907.Bfl225DNA polymerase III epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing funct [...]
lpcA protein networkhttps://string-db.org/network/203907.Bfl226Phosphoheptose isomerase; COG category=G.
ahpC protein networkhttps://string-db.org/network/203907.Bfl228Alkyl hydroperoxide reductase C22 protein; EC_number 1.6.4.-; COG category=O.
queA protein networkhttps://string-db.org/network/203907.Bfl229S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ [...]
tgt protein networkhttps://string-db.org/network/203907.Bfl230Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in [...]
yajC protein networkhttps://string-db.org/network/203907.Bfl231Preprotein translocase YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into memb [...]
secD protein networkhttps://string-db.org/network/203907.Bfl232Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete pr [...]
secF protein networkhttps://string-db.org/network/203907.Bfl233Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete pr [...]
ribD protein networkhttps://string-db.org/network/203907.Bfl234Bifunctional pyrimidine deaminase/reductase in pathway of riboflavin synthesis; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyr [...]
ribH protein networkhttps://string-db.org/network/203907.Bfl2356,7-dimethyl-8-ribityllumazine synthase (riboflavin synthase beta chain); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-di [...]
nusB protein networkhttps://string-db.org/network/203907.Bfl236Transcription termination; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribos [...]
pgpA protein networkhttps://string-db.org/network/203907.Bfl237Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
dxs protein networkhttps://string-db.org/network/203907.Bfl2381-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP) [...]
thiI protein networkhttps://string-db.org/network/203907.Bfl239Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also cataly [...]
yajR protein networkhttps://string-db.org/network/203907.Bfl240MFS family transporter; COG category=GEP.
cyoE protein networkhttps://string-db.org/network/203907.Bfl241Protohaeme IX farnesyltransferase (haeme O biosynthesis); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farn [...]
cyoD protein networkhttps://string-db.org/network/203907.Bfl242Cytochrome O ubiquinol oxidase subunit CyoD; COG category=C.
cyoC protein networkhttps://string-db.org/network/203907.Bfl243Cytochrome o ubiquinol oxidase subunit III; COG category=C.
cyoB protein networkhttps://string-db.org/network/203907.Bfl244Cytochrome o ubiquinol oxidase subunit I; COG category=C; Belongs to the heme-copper respiratory oxidase family.
cyoA protein networkhttps://string-db.org/network/203907.Bfl245Cytochrome o ubiquinol oxidase subunit II; COG category=C.
clpP protein networkhttps://string-db.org/network/203907.Bfl246ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
clpX protein networkhttps://string-db.org/network/203907.Bfl247ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in th [...]
yggX protein networkhttps://string-db.org/network/203907.Bfl248Putative Fe-S cluster protector protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosyn [...]
mutY protein networkhttps://string-db.org/network/203907.Bfl249A/G-specific adenine glycosylase; COG category=L.
yqgF protein networkhttps://string-db.org/network/203907.Bfl250Putative endonuclease involved in recombination; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.
yqgE protein networkhttps://string-db.org/network/203907.Bfl251Putative transcriptional regulator; COG category=K; Belongs to the UPF0301 (AlgH) family.
metK protein networkhttps://string-db.org/network/203907.Bfl252S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet forma [...]
speB protein networkhttps://string-db.org/network/203907.Bfl253Agmatine ureohydrolase; Catalyzes the formation of putrescine from agmatine.
pgk protein networkhttps://string-db.org/network/203907.Bfl254Phosphoglycerate kinase; COG category=G; Belongs to the phosphoglycerate kinase family.
fba protein networkhttps://string-db.org/network/203907.Bfl255Fructose 1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphos [...]
rpiA protein networkhttps://string-db.org/network/203907.Bfl256Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
ygfA protein networkhttps://string-db.org/network/203907.Bfl257Ligase;5-formyltetrahydrofolate cycloligase family; COG category=H; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
ygfE protein networkhttps://string-db.org/network/203907.Bfl258Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation [...]
ubiH protein networkhttps://string-db.org/network/203907.Bfl2592-octaprenyl-6-methoxyphenol hydroxylase; COG category=H.
ygfZ protein networkhttps://string-db.org/network/203907.Bfl260Aminomethyltransferase; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via [...]
prfB protein networkhttps://string-db.org/network/203907.Bfl261Peptide chain release factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
lysS protein networkhttps://string-db.org/network/203907.Bfl262lysyl-tRNA synthetase; COG category=J; Belongs to the class-II aminoacyl-tRNA synthetase family.
lysA protein networkhttps://string-db.org/network/203907.Bfl263Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
ygdP protein networkhttps://string-db.org/network/203907.Bfl264NTP pyrophospohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can [...]
lgt protein networkhttps://string-db.org/network/203907.Bfl265Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
recC protein networkhttps://string-db.org/network/203907.Bfl266Exonuclease V, subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirect [...]
recD protein networkhttps://string-db.org/network/203907.Bfl267Exonuclease V, alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidi [...]
recB protein networkhttps://string-db.org/network/203907.Bfl268Exonuclease V, beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidir [...]
dapD protein networkhttps://string-db.org/network/203907.Bfl2692,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; COG category=E; Belongs to the transferase hexapeptide repeat family.
map protein networkhttps://string-db.org/network/203907.Bfl270Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
rpsB protein networkhttps://string-db.org/network/203907.Bfl27130S ribosomal protein S2; COG category=J; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/203907.Bfl272Elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stag [...]
pyrH protein networkhttps://string-db.org/network/203907.Bfl273Uridine 5'-monophosphate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
frr protein networkhttps://string-db.org/network/203907.Bfl274Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
dxr protein networkhttps://string-db.org/network/203907.Bfl2751-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).
uppS protein networkhttps://string-db.org/network/203907.Bfl276Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,3 [...]
cdsA protein networkhttps://string-db.org/network/203907.Bfl277Phosphatidate cytidylyltransferase; COG category=I; Belongs to the CDS family.
yaeL protein networkhttps://string-db.org/network/203907.Bfl278Membrane-associated Zn-dependent protease; COG category=M.
yaeT protein networkhttps://string-db.org/network/203907.Bfl279Outer membrane protein precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, wi [...]
hlpA protein networkhttps://string-db.org/network/203907.Bfl280Histone-like protein, located in outer membrane; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates durin [...]
lpxD protein networkhttps://string-db.org/network/203907.Bfl281UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved [...]
fabZ protein networkhttps://string-db.org/network/203907.Bfl282(3R)-hydroxymyristol acyl carrier protein dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and [...]
lpxA protein networkhttps://string-db.org/network/203907.Bfl283acyl-[acyl-carrier-protein]:UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membr [...]
lpxB protein networkhttps://string-db.org/network/203907.Bfl284lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid t [...]
rnhB protein networkhttps://string-db.org/network/203907.Bfl285Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
dnaE protein networkhttps://string-db.org/network/203907.Bfl286DNA polymerase III, alpha chain; COG category=L.
accA protein networkhttps://string-db.org/network/203907.Bfl287Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on [...]
mesJ protein networkhttps://string-db.org/network/203907.Bfl288Cell cycle protein MesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is conve [...]
proS protein networkhttps://string-db.org/network/203907.Bfl289prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
accC protein networkhttps://string-db.org/network/203907.Bfl291Pseudogene of YaeD, conserved hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier [...]
accB protein networkhttps://string-db.org/network/203907.Bfl292acetylCoA carboxylase, BCCP subunit, carrier of biotin; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carr [...]
aroQ protein networkhttps://string-db.org/network/203907.Bfl2933-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
mreB protein networkhttps://string-db.org/network/203907.Bfl294Rod shape-determining protein MreB; COG category=D.
mreC protein networkhttps://string-db.org/network/203907.Bfl295Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
mreD protein networkhttps://string-db.org/network/203907.Bfl296Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
tldD protein networkhttps://string-db.org/network/203907.Bfl297TldD protein; COG category=R.
pmbA protein networkhttps://string-db.org/network/203907.Bfl298PmbA protein; COG category=R.
lon protein networkhttps://string-db.org/network/203907.Bfl299Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular home [...]
apt protein networkhttps://string-db.org/network/203907.Bfl300Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
dnaX protein networkhttps://string-db.org/network/203907.Bfl301DNA polymerase III subunit gamma; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exon [...]
adk protein networkhttps://string-db.org/network/203907.Bfl302Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
ybbF protein networkhttps://string-db.org/network/203907.Bfl303UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water [...]
cysS protein networkhttps://string-db.org/network/203907.Bfl304cysteinyl-tRNA synthetase; COG category=J; Belongs to the class-I aminoacyl-tRNA synthetase family.
folD protein networkhttps://string-db.org/network/203907.Bfl305FolD bifunctional protein [includes: methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of [...]
ytfF protein networkhttps://string-db.org/network/203907.Bfl307Permease of the drug/metabolite transporter (DMT) superfamily; COG category=GER.
mrdB protein networkhttps://string-db.org/network/203907.Bfl308Rod shape-determining membrane protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
mrdA protein networkhttps://string-db.org/network/203907.Bfl309Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
ybeB protein networkhttps://string-db.org/network/203907.Bfl310Unknown function family DUF143; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 3 [...]
holA protein networkhttps://string-db.org/network/203907.Bfl311DNA polymerase III, delta subunit; COG category=L.
rlpB protein networkhttps://string-db.org/network/203907.Bfl312Rare lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS [...]
leuS protein networkhttps://string-db.org/network/203907.Bfl313leucyl-tRNA synthetase; COG category=J; Belongs to the class-I aminoacyl-tRNA synthetase family.
lnt protein networkhttps://string-db.org/network/203907.Bfl314Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrol [...]
ybeX protein networkhttps://string-db.org/network/203907.Bfl315Haemolysin-related protein; COG category=R.
ybeY protein networkhttps://string-db.org/network/203907.Bfl316Predicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
phoL protein networkhttps://string-db.org/network/203907.Bfl317PhoH-like ATP-binding protein; COG category=T.
ubiF protein networkhttps://string-db.org/network/203907.Bfl318Monooxygenase; COG category=HC.
nagA protein networkhttps://string-db.org/network/203907.Bfl322N-acetylglucosamine-6-phosphate deacetylase; COG category=G.
nagB protein networkhttps://string-db.org/network/203907.Bfl323Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glu [...]
glnS protein networkhttps://string-db.org/network/203907.Bfl324glutaminyl-tRNA synthetase; COG category=J.
pgm protein networkhttps://string-db.org/network/203907.Bfl326Phosphoglucomutase; COG category=G.
sdhC protein networkhttps://string-db.org/network/203907.Bfl327Succinate dehydrogenase cytochrome b-556 subunit; COG category=C.
sdhD protein networkhttps://string-db.org/network/203907.Bfl328Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
sdhA protein networkhttps://string-db.org/network/203907.Bfl329Succinate dehydrogenase flavoprotein subunit; COG category=C; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
sdhB protein networkhttps://string-db.org/network/203907.Bfl330Succinate dehydrogenase iron-sulfur protein; COG category=C.
sucA protein networkhttps://string-db.org/network/203907.Bfl3312-oxoglutarate dehydrogenase E1 component; COG category=C.
sucB protein networkhttps://string-db.org/network/203907.Bfl332Dihydrolipoamide succinyltransferase component (E2); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succin [...]
sucC protein networkhttps://string-db.org/network/203907.Bfl333succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus repres [...]
sucD protein networkhttps://string-db.org/network/203907.Bfl334succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus repre [...]
tolQ protein networkhttps://string-db.org/network/203907.Bfl335TolQ protein; COG category=N.
tolR protein networkhttps://string-db.org/network/203907.Bfl336tolR protein; COG category=N.
tolA protein networkhttps://string-db.org/network/203907.Bfl337tolA protein; COG category=N.
tolB protein networkhttps://string-db.org/network/203907.Bfl338tolB protein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies [...]
pal protein networkhttps://string-db.org/network/203907.Bfl339Peptidoglycan-associated lipoprotein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane [...]
ybgF protein networkhttps://string-db.org/network/203907.Bfl340Predicted lipoprotein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
ybhE protein networkhttps://string-db.org/network/203907.Bfl3413-carboxymuconate cyclase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.
gpmA protein networkhttps://string-db.org/network/203907.Bfl342Phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
ybhL protein networkhttps://string-db.org/network/203907.Bfl343Integral membrane protein interacts with FtsH; COG category=R; Belongs to the BI1 family.
ychF protein networkhttps://string-db.org/network/203907.Bfl344Predicted GTPase; COG category=R.
pth protein networkhttps://string-db.org/network/203907.Bfl345peptidyl-tRNA hydrolase; COG category=J.
prsA protein networkhttps://string-db.org/network/203907.Bfl346Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
ipk protein networkhttps://string-db.org/network/203907.Bfl347Isopentenyl monophosphate kinase; COG category=S; Belongs to the GHMP kinase family. IspE subfamily.
prfA protein networkhttps://string-db.org/network/203907.Bfl348Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
hemK protein networkhttps://string-db.org/network/203907.Bfl349Methylase of polypeptide chain release factors; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ moti [...]
kdsA protein networkhttps://string-db.org/network/203907.Bfl3502-dehydro-3-deoxyphosphooctonate aldolase; COG category=E; Belongs to the KdsA family.
thrS protein networkhttps://string-db.org/network/203907.Bfl351threonyl-tRNA synthetase; COG category=J.
infC protein networkhttps://string-db.org/network/203907.Bfl352Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
rpmI protein networkhttps://string-db.org/network/203907.Bfl35350S ribosomal subunit protein L35; COG category=J; Belongs to the bacterial ribosomal protein bL35 family.
rplT protein networkhttps://string-db.org/network/203907.Bfl35450S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesiz [...]
pheS protein networkhttps://string-db.org/network/203907.Bfl355phenylalanyl-tRNA synthetase alpha chain; COG category=J; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
pheT protein networkhttps://string-db.org/network/203907.Bfl356phenylalanyl-tRNA synthetase beta chain; COG category=J; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
lplA protein networkhttps://string-db.org/network/203907.Bfl357Lipoate-protein ligase A; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dep [...]
sufA protein networkhttps://string-db.org/network/203907.Bfl358HesB-like domain; COG category=S; Belongs to the HesB/IscA family.
sufB protein networkhttps://string-db.org/network/203907.Bfl359ABC transporter sufB; COG category=R.
sufC protein networkhttps://string-db.org/network/203907.Bfl360Probable ATP-dependent transporter sufC; COG category=R.
sufD protein networkhttps://string-db.org/network/203907.Bfl361Required for stability of iron-sulfur component of FhuF; COG category=R.
sufS protein networkhttps://string-db.org/network/203907.Bfl362Selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomo [...]
ynhA protein networkhttps://string-db.org/network/203907.Bfl363SufE protein probably involved in Fe-S center assembly; COG category=R.
lpp protein networkhttps://string-db.org/network/203907.Bfl364Major outer membrane lipoprotein; COG category=M.
ribE protein networkhttps://string-db.org/network/203907.Bfl366Riboflavin synthase alpha chain; COG category=H.
ydhD protein networkhttps://string-db.org/network/203907.Bfl367Glutaredoxin; COG category=O; Belongs to the glutaredoxin family. Monothiol subfamily.
rnt protein networkhttps://string-db.org/network/203907.Bfl368Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP [...]
slyA protein networkhttps://string-db.org/network/203907.Bfl369Transcriptional regulator SlyA; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.
pdxH protein networkhttps://string-db.org/network/203907.Bfl370Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
tyrS protein networkhttps://string-db.org/network/203907.Bfl371tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
nth protein networkhttps://string-db.org/network/203907.Bfl372Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- [...]
fumC protein networkhttps://string-db.org/network/203907.Bfl373Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily [...]
eaeH protein networkhttps://string-db.org/network/203907.Bfl374Putative adhesin; COG category=R.
ubiX protein networkhttps://string-db.org/network/203907.Bfl3753-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylas [...]
kdsB protein networkhttps://string-db.org/network/203907.Bfl3763-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
ycaR protein networkhttps://string-db.org/network/203907.Bfl377Trm112p-like protein; COG category=R; Belongs to the UPF0434 family.
lpxK protein networkhttps://string-db.org/network/203907.Bfl378Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis [...]
msbA protein networkhttps://string-db.org/network/203907.Bfl379Probable transport ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form [...]
rpsA protein networkhttps://string-db.org/network/203907.Bfl38030S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
cmk protein networkhttps://string-db.org/network/203907.Bfl381Cytidylate kinase; COG category=F.
aroA protein networkhttps://string-db.org/network/203907.Bfl3823-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
serC protein networkhttps://string-db.org/network/203907.Bfl383Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belon [...]
serS protein networkhttps://string-db.org/network/203907.Bfl384seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
lolA protein networkhttps://string-db.org/network/203907.Bfl385Outer membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if t [...]
ftsK protein networkhttps://string-db.org/network/203907.Bfl386Cell division protein FtsK; COG category=D; Belongs to the FtsK/SpoIIIE/SftA family.
trxB protein networkhttps://string-db.org/network/203907.Bfl387Thioredoxin reductase; COG category=O.
infA protein networkhttps://string-db.org/network/203907.Bfl388Initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) s [...]
oprC protein networkhttps://string-db.org/network/203907.Bfl389Outer membrane protein OprC; COG category=N.
mltE protein networkhttps://string-db.org/network/203907.Bfl391Membrane-bound lytic murein transglycosylase E; COG category=M.
trmU protein networkhttps://string-db.org/network/203907.Bfl392tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of [...]
purB protein networkhttps://string-db.org/network/203907.Bfl393Adenylosuccinate lyase; COG category=F; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
lolE protein networkhttps://string-db.org/network/203907.Bfl394ABC transporter integral membrane subunit; COG category=M.
lolD protein networkhttps://string-db.org/network/203907.Bfl395ABC transporter ATP-binding subunit; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the peripl [...]
ycfU protein networkhttps://string-db.org/network/203907.Bfl396ABC transporter integral membrane subunit; COG category=M.
ycfM protein networkhttps://string-db.org/network/203907.Bfl397Collagen-binding surface adhesin Spad (antigen I/II family); COG category=M.
ycfF protein networkhttps://string-db.org/network/203907.Bfl398HIT family hydrolase; COG category=FGR.
ycfH protein networkhttps://string-db.org/network/203907.Bfl399Mg-dependent DNase; COG category=L.
holB protein networkhttps://string-db.org/network/203907.Bfl400DNA polymerase III, delta prime subunit; COG category=L.
tmk protein networkhttps://string-db.org/network/203907.Bfl401Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
pabC protein networkhttps://string-db.org/network/203907.Bfl4024-amino-4-deoxychorismate lyase; COG category=E.
acpP protein networkhttps://string-db.org/network/203907.Bfl403Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
fabG protein networkhttps://string-db.org/network/203907.Bfl4043-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cy [...]
fabD protein networkhttps://string-db.org/network/203907.Bfl405Malonyl CoA-acyl carrier protein transacylase; COG category=I.
fabH protein networkhttps://string-db.org/network/203907.Bfl4063-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first [...]
plsX protein networkhttps://string-db.org/network/203907.Bfl407Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fa [...]
rpmF protein networkhttps://string-db.org/network/203907.Bfl40850S ribosomal protein L32; COG category=J; Belongs to the bacterial ribosomal protein bL32 family.
rluC protein networkhttps://string-db.org/network/203907.Bfl409Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
rne protein networkhttps://string-db.org/network/203907.Bfl410COG category=J.
htrB protein networkhttps://string-db.org/network/203907.Bfl411Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
pgsA protein networkhttps://string-db.org/network/203907.Bfl415tRNA-Cys; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
yccK protein networkhttps://string-db.org/network/203907.Bfl418Dissimilatory sulfite reductase, gamma subunit; Part of a sulfur-relay system.
yccV protein networkhttps://string-db.org/network/203907.Bfl419Conserved hypothetical protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.
fabA protein networkhttps://string-db.org/network/203907.Bfl420D-3-hydroxydecanoyl-(acyl carrier-protein); Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and [...]
asnS protein networkhttps://string-db.org/network/203907.Bfl421asparaginyl-tRNA synthetase; COG category=J.
aspC protein networkhttps://string-db.org/network/203907.Bfl422Aspartate aminotransferase; COG category=E.
ycbL protein networkhttps://string-db.org/network/203907.Bfl423Zn-dependent hydrolase; COG category=R.
fabI protein networkhttps://string-db.org/network/203907.Bfl424Enoyl-[acyl-carrier-protein] reductase (NADH); COG category=I.
ribA protein networkhttps://string-db.org/network/203907.Bfl425GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
trpE protein networkhttps://string-db.org/network/203907.Bfl426Anthranilate synthase component I; COG category=E.
trpG protein networkhttps://string-db.org/network/203907.Bfl427Anthranilate synthase component II; COG category=E.
trpD protein networkhttps://string-db.org/network/203907.Bfl428Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranila [...]
trpC protein networkhttps://string-db.org/network/203907.Bfl429Indole-3-glycerol phosphate synthase; COG category=E; Belongs to the TrpF family.
trpB protein networkhttps://string-db.org/network/203907.Bfl430Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpA protein networkhttps://string-db.org/network/203907.Bfl431Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
tonB protein networkhttps://string-db.org/network/203907.Bfl432TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to t [...]
cls protein networkhttps://string-db.org/network/203907.Bfl433Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
tdk protein networkhttps://string-db.org/network/203907.Bfl434Thymidine kinase; COG category=F.
xthA protein networkhttps://string-db.org/network/203907.Bfl435Exodeoxyribonuclease III; COG category=L.
sppA protein networkhttps://string-db.org/network/203907.Bfl436Protease IV, a signal peptide peptidase; COG category=N.
gapA protein networkhttps://string-db.org/network/203907.Bfl437Glyceraldehyde 3-phosphate dehydrogenase A; COG category=G; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
dsbB protein networkhttps://string-db.org/network/203907.Bfl438Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
minC protein networkhttps://string-db.org/network/203907.Bfl439Septum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments tha [...]
minD protein networkhttps://string-db.org/network/203907.Bfl440Septum site determining protein MinD; COG category=D.
minE protein networkhttps://string-db.org/network/203907.Bfl441Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures c [...]
yeaZ protein networkhttps://string-db.org/network/203907.Bfl442Peptidase M22; COG category=O.
pabB protein networkhttps://string-db.org/network/203907.Bfl443Para-aminobenzoate synthase component I; COG category=E.
yoaE protein networkhttps://string-db.org/network/203907.Bfl444Membrane protein TerC (probably for efflux of tellurium and other ions); COG category=P.
manX protein networkhttps://string-db.org/network/203907.Bfl445PTS system, mannose-specific IIAB component; COG category=G.
manY protein networkhttps://string-db.org/network/203907.Bfl446Phosphotransferase enzyme II, C component; COG category=G.
manZ protein networkhttps://string-db.org/network/203907.Bfl447Phosphotransferase enzyme II, D component; COG category=G.
cspC protein networkhttps://string-db.org/network/203907.Bfl448Cold shock-like protein CspC; COG category=T.
zwf protein networkhttps://string-db.org/network/203907.Bfl449Glucose 6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
pykA protein networkhttps://string-db.org/network/203907.Bfl450Pyruvate kinase A; COG category=G; Belongs to the pyruvate kinase family.
yebA protein networkhttps://string-db.org/network/203907.Bfl451Membrane protein related to metalloendopeptidases; COG category=O.
aspS protein networkhttps://string-db.org/network/203907.Bfl452aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
argS protein networkhttps://string-db.org/network/203907.Bfl453arginyl-tRNA synthetase; COG category=J.
mviN protein networkhttps://string-db.org/network/203907.Bfl454Virulence factor MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
yceL protein networkhttps://string-db.org/network/203907.Bfl455Arabinose efflux permease; COG category=G.
gutQ protein networkhttps://string-db.org/network/203907.Bfl459Sugar phosphate isomerase involved in capsule formation; COG category=M.
yeeX protein networkhttps://string-db.org/network/203907.Bfl460DUF496; COG category=R; Belongs to the UPF0265 family.
sbcB protein networkhttps://string-db.org/network/203907.Bfl461Exodeoxyribonuclease I; COG category=L.
hisG protein networkhttps://string-db.org/network/203907.Bfl462ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
hisD protein networkhttps://string-db.org/network/203907.Bfl463Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisC protein networkhttps://string-db.org/network/203907.Bfl464Histidinol-phosphate aminotransferase; COG category=E; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
hisB protein networkhttps://string-db.org/network/203907.Bfl465Imidazoleglycerol-phosphate dehydratase; COG category=E; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
hisH protein networkhttps://string-db.org/network/203907.Bfl466Glutamine amidotransferase, subunit with HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamat [...]
hisA protein networkhttps://string-db.org/network/203907.Bfl467Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; COG category=E.
hisF protein networkhttps://string-db.org/network/203907.Bfl468Imidazole glycerol phosphate synthase, subunit with HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity tha [...]
hisI protein networkhttps://string-db.org/network/203907.Bfl469phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase; COG category=E; In the C-terminal section; belongs to the PRA-PH family.
gnd protein networkhttps://string-db.org/network/203907.Bfl4706-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
metG protein networkhttps://string-db.org/network/203907.Bfl471methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
folE protein networkhttps://string-db.org/network/203907.Bfl472GTP cyclohydrolase I; COG category=H.
rplY protein networkhttps://string-db.org/network/203907.Bfl47350s ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
ddlA protein networkhttps://string-db.org/network/203907.Bfl474D-alanine:D-alanine ligase A; Cell wall formation.
omp protein networkhttps://string-db.org/network/203907.Bfl475Outer membrane protein; COG category=N.
gyrA protein networkhttps://string-db.org/network/203907.Bfl476DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
ubiG protein networkhttps://string-db.org/network/203907.Bfl4773-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG [...]
nrdA protein networkhttps://string-db.org/network/203907.Bfl478Ribonucleoside-diphosphate reductase 1 alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
nrdB protein networkhttps://string-db.org/network/203907.Bfl479Ribonucleoside-diphosphate reductase 1 beta chain; COG category=F.
yfaE protein networkhttps://string-db.org/network/203907.Bfl480Ferredoxin; COG category=C.
nuoN protein networkhttps://string-db.org/network/203907.Bfl481NADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoM protein networkhttps://string-db.org/network/203907.Bfl482NADH dehydrogenase I chain M; COG category=C.
nuoL protein networkhttps://string-db.org/network/203907.Bfl483NADH dehydrogenase I chain L; COG category=C.
nuoK protein networkhttps://string-db.org/network/203907.Bfl484NADH dehydrogenase I chain k; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoJ protein networkhttps://string-db.org/network/203907.Bfl485NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation [...]
nuoI protein networkhttps://string-db.org/network/203907.Bfl486NADH dehydrogenase I chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoH protein networkhttps://string-db.org/network/203907.Bfl487NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoG protein networkhttps://string-db.org/network/203907.Bfl488NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoF protein networkhttps://string-db.org/network/203907.Bfl489NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
nuoE protein networkhttps://string-db.org/network/203907.Bfl490NADH dehydrogenase I chain E; COG category=C.
nuoCD protein networkhttps://string-db.org/network/203907.Bfl491NADH dehydrogenase I chain C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoB protein networkhttps://string-db.org/network/203907.Bfl492NADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoA protein networkhttps://string-db.org/network/203907.Bfl493NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
folC protein networkhttps://string-db.org/network/203907.Bfl494Folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate [...]
accD protein networkhttps://string-db.org/network/203907.Bfl495acetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and [...]
truA protein networkhttps://string-db.org/network/203907.Bfl496tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
pdxB protein networkhttps://string-db.org/network/203907.Bfl497Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
fabB protein networkhttps://string-db.org/network/203907.Bfl4983-oxoacyl-[acyl-carrier-protein] synthase I; COG category=I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
yfcB protein networkhttps://string-db.org/network/203907.Bfl499Predicted rRNA or tRNA methylase; COG category=AJ; Belongs to the protein N5-glutamine methyltransferase family.
aroC protein networkhttps://string-db.org/network/203907.Bfl500Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
mntH protein networkhttps://string-db.org/network/203907.Bfl502Manganese transport protein MntH; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
nupC protein networkhttps://string-db.org/network/203907.Bfl503Nucleoside permease NupC; COG category=F.
gltX protein networkhttps://string-db.org/network/203907.Bfl504glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
lig protein networkhttps://string-db.org/network/203907.Bfl507DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sourc [...]
cysK protein networkhttps://string-db.org/network/203907.Bfl508Cysteine synthase A; COG category=E; Belongs to the cysteine synthase/cystathionine beta- synthase family.
ptsH protein networkhttps://string-db.org/network/203907.Bfl509Phosphocarrier protein HPr; COG category=G.
ptsI protein networkhttps://string-db.org/network/203907.Bfl510Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate ac [...]
cysA protein networkhttps://string-db.org/network/203907.Bfl511Sulphate transport ATP-binding protein CysA; COG category=P; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
cysW protein networkhttps://string-db.org/network/203907.Bfl512Sulphate transport system permease protein CysW; COG category=P.
cysU protein networkhttps://string-db.org/network/203907.Bfl513Sulphate transport system permease protein CysU; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport syst [...]
cysP protein networkhttps://string-db.org/network/203907.Bfl514Thiosulphate-binding protein precursor; COG category=P.
talA protein networkhttps://string-db.org/network/203907.Bfl515Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
tktA protein networkhttps://string-db.org/network/203907.Bfl516Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
dapE protein networkhttps://string-db.org/network/203907.Bfl517Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in [...]
dapA protein networkhttps://string-db.org/network/203907.Bfl518Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
bcp protein networkhttps://string-db.org/network/203907.Bfl519Bacterioferritin comigratory protein; COG category=O.
upp protein networkhttps://string-db.org/network/203907.Bfl520Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
ureG protein networkhttps://string-db.org/network/203907.Bfl521Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; Facilitates the functional incorporation of the urease nickel metallocenter. This process requir [...]
ureF protein networkhttps://string-db.org/network/203907.Bfl522Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
ureC protein networkhttps://string-db.org/network/203907.Bfl523Urea amidohydrolase (urease) alpha subunit; COG category=E; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
ureB protein networkhttps://string-db.org/network/203907.Bfl524Urea amidohydrolase (urease) beta subunit; COG category=E; Belongs to the urease beta subunit family.
ureA protein networkhttps://string-db.org/network/203907.Bfl525Urea amidohydrolase (urease) gamma subunit; COG category=E; Belongs to the urease gamma subunit family.
ureD protein networkhttps://string-db.org/network/203907.Bfl526Urease accessory protein D; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
guaA protein networkhttps://string-db.org/network/203907.Bfl527GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
guaB protein networkhttps://string-db.org/network/203907.Bfl528Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesi [...]
mqo protein networkhttps://string-db.org/network/203907.Bfl529Probable malate:quinone oxidoreductase (malate dehydrogenase (acceptor)); COG category=R.
engA protein networkhttps://string-db.org/network/203907.Bfl530Predicted GTPase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase fa [...]
hisS protein networkhttps://string-db.org/network/203907.Bfl531histidyl-tRNA synthetase; COG category=J.
ndk protein networkhttps://string-db.org/network/203907.Bfl533Pseudogene of GcpE protein (protein E); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong me [...]
nifS protein networkhttps://string-db.org/network/203907.Bfl534L-cysteine desulfurase; COG category=E.
suhB protein networkhttps://string-db.org/network/203907.Bfl535Myo-inositol-1(or 4)-monophosphatase; COG category=G; Belongs to the inositol monophosphatase superfamily.
glyA protein networkhttps://string-db.org/network/203907.Bfl536Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
yfhC protein networkhttps://string-db.org/network/203907.Bfl537Cytosine/adenosine deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase [...]
acpS protein networkhttps://string-db.org/network/203907.Bfl538Holo-[acyl-carrier protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
pdxJ protein networkhttps://string-db.org/network/203907.Bfl539Pyridoxal phosphate biosynthetic protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate [...]
rnc protein networkhttps://string-db.org/network/203907.Bfl540Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
lepB protein networkhttps://string-db.org/network/203907.Bfl541Signal peptidase I; COG category=N; Belongs to the peptidase S26 family.
lepA protein networkhttps://string-db.org/network/203907.Bfl542GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
ung protein networkhttps://string-db.org/network/203907.Bfl543uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
grpE protein networkhttps://string-db.org/network/203907.Bfl544Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is [...]
yfjB protein networkhttps://string-db.org/network/203907.Bfl545Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically t [...]
smpA protein networkhttps://string-db.org/network/203907.Bfl546Small membrane protein A; COG category=S.
yfjG protein networkhttps://string-db.org/network/203907.Bfl547Oligoketide cyclase/lipid transport protein; COG category=I.
smpB protein networkhttps://string-db.org/network/203907.Bfl548tmRNA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. t [...]
emrE protein networkhttps://string-db.org/network/203907.Bfl550emrE protein (methyl viologen resistance protein C) (ethidium resistance protein); COG category=P.
pssA protein networkhttps://string-db.org/network/203907.Bfl551Phosphatidylserine synthase (CDP-diacylglycerol-serine O-phosphatidyltransferase); COG category=I.
purH protein networkhttps://string-db.org/network/203907.Bfl555Phosphoribosylaminoimidazolecarboxamide formyltransferase, IMP cyclohydrolase and MGS-like domain; COG category=F.
rpoC protein networkhttps://string-db.org/network/203907.Bfl556DNA-directed RNA polymerase, beta-prime-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/203907.Bfl557DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/203907.Bfl55850S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs t [...]
rplJ protein networkhttps://string-db.org/network/203907.Bfl55950S ribosomal subunit protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal riboso [...]
rplA protein networkhttps://string-db.org/network/203907.Bfl56050S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/203907.Bfl56150S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/203907.Bfl562Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the [...]
secE protein networkhttps://string-db.org/network/203907.Bfl563Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Be [...]
tuf protein networkhttps://string-db.org/network/203907.Bfl564Elongation factor Tu (EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
fusA protein networkhttps://string-db.org/network/203907.Bfl565Elongation factor G (EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to th [...]
rpsG protein networkhttps://string-db.org/network/203907.Bfl56630S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subu [...]
rpsL protein networkhttps://string-db.org/network/203907.Bfl56730S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.
pabA protein networkhttps://string-db.org/network/203907.Bfl568Para-aminobenzoate synthase, glutamine amidotransferase component II; COG category=E.
trpS protein networkhttps://string-db.org/network/203907.Bfl569tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
rpe protein networkhttps://string-db.org/network/203907.Bfl570Ribulose-phosphate 3-epimerase; COG category=G; Belongs to the ribulose-phosphate 3-epimerase family.
aroB protein networkhttps://string-db.org/network/203907.Bfl5713-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquin [...]
aroK protein networkhttps://string-db.org/network/203907.Bfl572Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
yhgI protein networkhttps://string-db.org/network/203907.Bfl573Thioredoxin-like proteins and domains; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe [...]
asd protein networkhttps://string-db.org/network/203907.Bfl574Aspartate-semialdehyde dehydrogenase; COG category=E; Belongs to the aspartate-semialdehyde dehydrogenase family.
yhgN protein networkhttps://string-db.org/network/203907.Bfl575Integral membrane protein of the MarC family; COG category=S.
yigL protein networkhttps://string-db.org/network/203907.Bfl576Predicted hydrolase of the HAD superfamily; COG category=R.
corA protein networkhttps://string-db.org/network/203907.Bfl577Magnesium and cobalt transport protein; Mediates influx of magnesium ions. Can also mediate cobalt and manganese uptake (By similarity). Alternates between open and closed states. Activated by lo [...]
yigB protein networkhttps://string-db.org/network/203907.Bfl578Predicted hydrolase of the HAD superfamily; COG category=R.
dapF protein networkhttps://string-db.org/network/203907.Bfl579Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
hemC protein networkhttps://string-db.org/network/203907.Bfl580Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
hemD protein networkhttps://string-db.org/network/203907.Bfl581Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
rho protein networkhttps://string-db.org/network/203907.Bfl586Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
trxA protein networkhttps://string-db.org/network/203907.Bfl587Thioredoxin 1, redox factor; COG category=O; Belongs to the thioredoxin family.
ilvC protein networkhttps://string-db.org/network/203907.Bfl588Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
ilvA protein networkhttps://string-db.org/network/203907.Bfl589Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production [...]
ilvD protein networkhttps://string-db.org/network/203907.Bfl590Dihydroxyacid dehydratase; COG category=E; Belongs to the IlvD/Edd family.
ilvE protein networkhttps://string-db.org/network/203907.Bfl591Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
ilvM protein networkhttps://string-db.org/network/203907.Bfl592Acetolactate synthase II, small subunit; COG category=E.
ilvG protein networkhttps://string-db.org/network/203907.Bfl593Acetolactate synthase II, large subunit; COG category=E.
metF protein networkhttps://string-db.org/network/203907.Bfl5975,10 methylenetetrahydrofolate reductase; EC_number 1.7.99.5; COG category=E; Belongs to the methylenetetrahydrofolate reductase family.
metB protein networkhttps://string-db.org/network/203907.Bfl598Cystathionine gamma-synthase; COG category=E.
rpmE protein networkhttps://string-db.org/network/203907.Bfl59950S ribosomal protein L31; Binds the 23S rRNA.
fpr protein networkhttps://string-db.org/network/203907.Bfl600ferredoxin--NADP reductase; COG category=C.
tpiA protein networkhttps://string-db.org/network/203907.Bfl601Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
pfkA protein networkhttps://string-db.org/network/203907.Bfl6026-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
cysE protein networkhttps://string-db.org/network/203907.Bfl603Serine acetyltransferase; COG category=E; Belongs to the transferase hexapeptide repeat family.
gpsA protein networkhttps://string-db.org/network/203907.Bfl604Glycerol-3-phosphate dehydrogenase; COG category=C; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
grxC protein networkhttps://string-db.org/network/203907.Bfl605Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
yibN protein networkhttps://string-db.org/network/203907.Bfl606Rhodanese-related sulfurtransferases; COG category=P.
rfaD protein networkhttps://string-db.org/network/203907.Bfl607ADP-L-Glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the [...]
rfaF protein networkhttps://string-db.org/network/203907.Bfl608ADP-heptose; COG category=M.
rfaC protein networkhttps://string-db.org/network/203907.Bfl609Lipopolysaccharide heptosyltransferase I; COG category=M.
kdtA protein networkhttps://string-db.org/network/203907.Bfl6103-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV( [...]
rpmG protein networkhttps://string-db.org/network/203907.Bfl61150S ribosomal subunit protein L33; COG category=J; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/203907.Bfl61250S ribosomal subunit protein L28; COG category=J; Belongs to the bacterial ribosomal protein bL28 family.
dut protein networkhttps://string-db.org/network/203907.Bfl613Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intrace [...]
yicC protein networkhttps://string-db.org/network/203907.Bfl614Uncharacterized stress-induced protein; COG category=S.
unknown-4 protein networkhttps://string-db.org/network/203907.Bfl615Transcription regulator protein, MarR family; COG category=K.
gmk protein networkhttps://string-db.org/network/203907.Bfl616Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
rpoZ protein networkhttps://string-db.org/network/203907.Bfl617DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha [...]
glnA protein networkhttps://string-db.org/network/203907.Bfl618Glutamine synthetase; COG category=E.
polA protein networkhttps://string-db.org/network/203907.Bfl619DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
yigC protein networkhttps://string-db.org/network/203907.Bfl6203-polyprenyl-4-hydroxybenzoate decarboxylase (ubiquinon biosynthesis); Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone b [...]
aarF protein networkhttps://string-db.org/network/203907.Bfl621Ubiquinone biosynthesis protein; COG category=R.
ubiE protein networkhttps://string-db.org/network/203907.Bfl622Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-m [...]
rumC protein networkhttps://string-db.org/network/203907.Bfl623RmuC family, DNA recombination; COG category=R.
udp protein networkhttps://string-db.org/network/203907.Bfl624Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as c [...]
metE protein networkhttps://string-db.org/network/203907.Bfl6255-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; [...]
rpoH protein networkhttps://string-db.org/network/203907.Bfl626RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involve [...]
ftsY protein networkhttps://string-db.org/network/203907.Bfl627Cell division protein FtsY; COG category=N.
yhhF protein networkhttps://string-db.org/network/203907.Bfl628N6-adenine-specific methylase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
pgi protein networkhttps://string-db.org/network/203907.Bfl629Glucose-6-phosphate isomerase; COG category=G.
metA protein networkhttps://string-db.org/network/203907.Bfl630Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.