Organism Overview: Mus musculus


 
Gnai3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000001Guanine nucleotide-binding protein G(i) subunit alpha; Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in [...]
Pbsn protein networkhttps://string-db.org/network/10090.ENSMUSP00000000003Probasin.
Hoxb9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000010Homeobox protein Hox-B9; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Cdc45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000028Cell division control protein 45 homolog; Required for initiation of chromosomal DNA replication; Belongs to the CDC45 family.
Apoh protein networkhttps://string-db.org/network/10090.ENSMUSP00000000049Beta-2-glycoprotein 1; Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation casca [...]
Cav2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000058Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein [...]
Klf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000080Krueppel-like factor 6; Transcriptional activator. Binds a GC box motif. Could play a role in B-cell growth and development (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein [...]
Cox5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000000090Cytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The re [...]
Tbx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000095T-box transcription factor TBX2; Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. Acts as a negative reg [...]
Ngfr protein networkhttps://string-db.org/network/10090.ENSMUSP00000000122Tumor necrosis factor receptor superfamily member 16; Low affinity neurotrophin receptor which can bind to mature NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds [...]
Wnt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000127Proto-oncogene Wnt-3; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcr [...]
Fer protein networkhttps://string-db.org/network/10090.ENSMUSP00000000129Tyrosine-protein kinase Fer; Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule as [...]
Actr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000137Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 c [...]
Gna12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000153Guanine nucleotide-binding protein subunit alpha-12; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Activat [...]
Itgb2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000000161Integrin beta-2-like protein; During inflammatory stimulation, plays a role in retaining Cxcl13-expressing cells at the site of the inflammatory response.
Pih1d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000171PIH1 domain-containing protein 2.
Sdhd protein networkhttps://string-db.org/network/10090.ENSMUSP00000000175Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial ele [...]
Fgf23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000186Fibroblast growth factor 23; Regulator of phosphate homeostasis (By similarity). Inhibits renal tubular phosphate transport by reducing SLC34A1 levels (By similarity). Acts directly on the parath [...]
Fgf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000187Fibroblast growth factor 6; Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration; Bel [...]
Ccnd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000188G1/S-specific cyclin-D2; Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the [...]
Ccl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000193C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization [...]
Ccl12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000194C-C motif chemokine 12; Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in aller [...]
Ncs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000199Neuronal calcium sensor 1; Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Ca [...]
Nalcn protein networkhttps://string-db.org/network/10090.ENSMUSP00000000201Sodium leak channel non-selective protein; Voltage-independent, cation-nonselective channel which is permeable to sodium, potassium and calcium ions. Regulates the resting membrane potential and [...]
Btbd17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000206BTB/POZ domain-containing protein 17.
Slfn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000208Schlafen 4.
Th protein networkhttps://string-db.org/network/10090.ENSMUSP00000000219Tyrosine 3-monooxygenase; Plays an important role in the physiology of adrenergic neurons.
Scnn1g protein networkhttps://string-db.org/network/10090.ENSMUSP00000000221Amiloride-sensitive sodium channel subunit gamma; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and [...]
Lhx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000253LIM/homeobox protein Lhx2; Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differen [...]
Clec2g protein networkhttps://string-db.org/network/10090.ENSMUSP00000000254C-type lectin domain family 2 member G; Inhibits osteoclast formation.
Gmpr protein networkhttps://string-db.org/network/10090.ENSMUSP00000000260GMP reductase 1; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, a [...]
Ifi202b protein networkhttps://string-db.org/network/10090.ENSMUSP00000000266Interferon-activable protein 202; Inhibits the transcriptional activity of several transcription factors, including NF-kappa-B p50 and p65, FOS, JUN, E2F1, E2F4, MYOD1 and myogenin. Has anti-apop [...]
Glra3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000275Glycine receptor subunit alpha-3; Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel characteristics depend on the subunit compos [...]
Scpep1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000287Retinoid-inducible serine carboxypeptidase; May be involved in vascular wall and kidney homeostasis; Belongs to the peptidase S10 family.
Mnt protein networkhttps://string-db.org/network/10090.ENSMUSP00000000291Max-binding protein MNT; Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'.
Itgb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000299Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interacti [...]
Hddc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000304HD domain-containing protein 2; Belongs to the HDDC2 family.
Tpd52l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000305Tumor protein D53.
Cdh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000312Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the s [...]
Cdh4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000314Cadherin-4; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the s [...]
Ckmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000317Creatine kinase U-type, mitochondrial; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role [...]
Bcl6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000000326B-cell CLL/lymphoma 6 member B protein; Acts as a sequence-specific transcriptional repressor in association with BCL6. Necessary for activation of naive T-cells to antigenic stimulation. May att [...]
Clec10a protein networkhttps://string-db.org/network/10090.ENSMUSP00000000327C-type lectin domain family 10 member A; Recognizes terminal galactose and N-acetylgalactosamine units. May participate in the interaction between tumoricidal macrophages and tumor cells. Plays a [...]
Alox12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000329Arachidonate 12-lipoxygenase, 12S-type; Catalyzes the regio and stereo-specific incorporation of a single molecule of dioxygen into free and esterified polyunsaturated fatty acids generating lipi [...]
Ccl11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000342Eotaxin; In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions), but not lymphocytes, ma [...]
Rtca protein networkhttps://string-db.org/network/10090.ENSMUSP00000000348RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenyl [...]
Dbt protein networkhttps://string-db.org/network/10090.ENSMUSP000000003492-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and [...]
Dazap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000356DAZ-associated protein 2.
Mcts1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000365Malignant T-cell-amplified sequence 1; Anti-oncogene that plays a role in cell cycle regulation; decreases cell doubling time and anchorage-dependent growth; shortens the duration of G1 transit t [...]
Rem1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000369GTP-binding protein REM 1; Promotes endothelial cell sprouting and actin cytoskeletal reorganization (By similarity). May be involved in angiogenesis. May function in Ca(2+) signaling; Belongs to [...]
Trappc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000384Trafficking protein particle complex subunit 10; May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Ccm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000388Cerebral cavernous malformations protein 2 homolog; Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilizat [...]
Tmprss2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000395Transmembrane protease serine 2 non-catalytic chain; Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions. The spi [...]
Egfl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000412Epidermal growth factor-like protein 6; May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly. Belongs to the nephronectin family.
Tssk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000421Testis-specific serine/threonine-protein kinase 3; May be involved in a signaling pathway during male germ cell development or mature sperm function; Belongs to the protein kinase superfamily. CA [...]
Myf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000445Myogenic factor 5; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occ [...]
Mkrn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000449Probable E3 ubiquitin-protein ligase makorin-2; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
Pparg protein networkhttps://string-db.org/network/10090.ENSMUSP00000000450Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear recepto [...]
Raf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000451RAF proto-oncogene serine/threonine-protein kinase; Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this c [...]
Plin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000466Perilipin-2; May be involved in development and maintenance of adipose tissue.
Pdgfb protein networkhttps://string-db.org/network/10090.ENSMUSP00000000500Platelet-derived growth factor subunit B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Poten [...]
Mcm7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000505DNA replication licensing factor MCM7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiat [...]
Acvrl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000542Serine/threonine-protein kinase receptor R3; Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a [...]
Grasp protein networkhttps://string-db.org/network/10090.ENSMUSP00000000543General receptor for phosphoinositides 1-associated scaffold protein; Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamat [...]
Acvr1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000000544Activin receptor type-1B; Transmembrane serine/threonine kinase activin type-1 receptor forming an activin receptor complex with activin receptor type-2 (ACVR2A or ACVR2B). Transduces the activin [...]
Ovgp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000573Oviduct-specific glycoprotein; Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development.
Adora3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000574Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase.
Sox9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000579Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as [...]
Rdx protein networkhttps://string-db.org/network/10090.ENSMUSP00000000590Radixin; Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.
C1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000000594Nuclear nucleic acid-binding protein C1D; Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MP [...]
Gm2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000000608Ganglioside GM2 activator; Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extra [...]
Clcn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000619H(+)/Cl(-) exchange transporter 4; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons (By similarity). Belongs to the chloride channel ( [...]
Sema4f protein networkhttps://string-db.org/network/10090.ENSMUSP00000000641Semaphorin-4F; Probable cell surface receptor that regulates oligodendroglial precursor cell migration. Might also regulate differentiation of oligodendroglial precursor cells (By similarity). Ha [...]
Hk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000642Hexokinase-2; Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D- fructose 6-phosphate, respectively) (By similarity). M [...]
Haao protein networkhttps://string-db.org/network/10090.ENSMUSP000000006873-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
Cd52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000696CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role.
Loxl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000707Lysyl oxidase homolog 3; Protein-lysine 6-oxidase that mediates the oxidation of peptidyl lysine residues to allysine in target proteins. Catalyzes the post-translational oxidative deamination of [...]
Tcl1b5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000717Protein TCL1B5; Belongs to the TCL1 family.
Tcl1b4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000718Protein TCL1B4; Belongs to the TCL1 family.
Kat2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000000724Histone acetyltransferase KAT2B; Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 an [...]
Rab5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000000727Ras-related protein Rab-5B; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.
Sult5a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000755Sulfotransferase; Belongs to the sulfotransferase 1 family.
Rpl13 protein networkhttps://string-db.org/network/10090.ENSMUSP0000000075660S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.
Chmp1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000000759Charged multivesicular body protein 1a; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodi [...]
Rpa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000767Replication protein A 70 kDa DNA-binding subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during [...]
Serpinf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000769Pigment epithelium-derived factor; Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stress [...]
Tubgcp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000776Gamma-tubulin complex component 3; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Ddx3x protein networkhttps://string-db.org/network/10090.ENSMUSP00000000804ATP-dependent RNA helicase DDX3X; Multifunctional ATP-dependent RNA helicase. The ATPase activity can be stimulated by various ribo-and deoxynucleic acids indicative for a relaxed substrate speci [...]
Il12rb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000808Interleukin-12 receptor subunit beta-1; Functions as an interleukin receptor which binds interleukin- 12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a [...]
Slc5a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000809Sodium/iodide cotransporter; Mediates iodide uptake in the thyroid gland; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Kcnn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000811Small conductance calcium-activated potassium channel protein 3; Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolariza [...]
Txnrd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000828Thioredoxin reductase 3; Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 [...]
Fasl protein networkhttps://string-db.org/network/10090.ENSMUSP00000000834Tumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T-cell-medi [...]
Il4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000889Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecu [...]
Necab3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000895N-terminal EF-hand calcium-binding protein 3; Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta (By similarity). May enhance [...]
Pxmp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000896Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family.
Dbh protein networkhttps://string-db.org/network/10090.ENSMUSP00000000910Soluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline.
Mmp11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000924Stromelysin-3; May play an important role in the progression of epithelial malignancies.
Smarcb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000925SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Core component of the BAF (SWI/SNF) complex. This ATP- dependent chromatin-remodeling complex plays [...]
Vpreb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000926Pre-B lymphocyte gene 3.
Hip1r protein networkhttps://string-db.org/network/10090.ENSMUSP00000000939Huntingtin-interacting protein 1-related protein; Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via [...]
Nsun5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000940Probable 28S rRNA (cytosine-C(5))-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of a cytosine in 28S rRNA. Belongs to the c [...]
Top1mt protein networkhttps://string-db.org/network/10090.ENSMUSP00000000958DNA topoisomerase I, mitochondrial; Releases the supercoiling and torsional tension of DNA introduced during duplication of mitochondrial DNA by transiently cleaving and rejoining one strand of t [...]
Hoxa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000000964Homeobox protein Hox-A1; Sequence-specific transcription factor. Regulates multiple developmental processes including brainstem, inner and outer ear, abducens nerve and cardiovascular development [...]
Oxa1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000000985Mitochondrial inner membrane protein OXA1L; Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome o [...]
Heatr6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001002HEAT repeat-containing protein 6.
Ccl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001008C-C motif chemokine 3; Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium [...]
Wfdc18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001009WAP four-disulfide core domain protein 18; Could have proteinase inhibiting capacity.
Aox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001027Aldehyde oxidase 1; Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such [...]
Icam4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001040Intercellular adhesion molecule 4; Adhesion molecule that binds to leukocyte adhesion LFA-1 protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrin [...]
Ilf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001042Interleukin enhancer-binding factor 2; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It [...]
S100a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001046Protein S100-A4; Belongs to the S-100 family.
S100a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001047Protein S100-A3; Binds both calcium and zinc. May be involved in calcium- dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation (By similarity).
S100a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001051Protein S100-A6; May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and in [...]
Icam2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001055Intercellular adhesion molecule 2; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA- [...]
Ern1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001059Serine/threonine-protein kinase/endoribonuclease IRE1; Serine/threonine-protein kinase and endoribonuclease that acts as a key sensor for the endoplasmic reticulum unfolded protein response (UPR) [...]
Sec24b protein networkhttps://string-db.org/network/10090.ENSMUSP00000001079Sec24-related gene family, member B (S. cerevisiae).
N4bp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001080NEDD4-binding protein 3; Plays a role in axon and dendrite arborization during cranial nerve development. May also be important for neural crest migration and early development of other anterior [...]
Rmnd5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000001081E3 ubiquitin-protein transferase RMND5B; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent pr [...]
Zfp276 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001092Zinc finger protein 276; May be involved in transcriptional regulation.
Mfsd10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001109Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non- steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as [...]
Grk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001112G protein-coupled receptor kinase 4; Specifically phosphorylates the activated forms of G protein- coupled receptors; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. [...]
Grk6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001115G protein-coupled receptor kinase 6; Specifically phosphorylates the activated forms of G protein- coupled receptors. Such receptor phosphorylation initiates beta- arrestin-mediated receptor dese [...]
Slc13a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001122Solute carrier family 13 member 2; Cotransport of sodium ions and dicarboxylates such as succinate and citrate.
Kctd10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001125BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(BACURD3) E3 ubiqui [...]
Slc46a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001126Proton-coupled folate transporter; Has been shown to act both as an intestinal proton-coupled high-affinity folate transporter and as an intestinal heme transporter which mediates heme uptake fro [...]
Poldip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001127Polymerase delta-interacting protein 2; Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites. May act [...]
Sebox protein networkhttps://string-db.org/network/10090.ENSMUSP00000001130Homeobox protein SEBOX; Probable transcription factor involved in the control of specification of mesoderm and endoderm; Belongs to the paired homeobox family.
Col6a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001147Collagen alpha-1(VI) chain; Collagen VI acts as a cell-binding protein; Belongs to the type VI collagen family.
Pcbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001148Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC.
Araf protein networkhttps://string-db.org/network/10090.ENSMUSP00000001155Serine/threonine-protein kinase A-Raf; Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade (By similarity).
Cfp protein networkhttps://string-db.org/network/10090.ENSMUSP00000001156Properdin; A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes (By similarity). Inhibits CFI-CFH mediated degradatio [...]
Cnnm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001166Metal transporter CNNM3; Probable metal transporter.
Ankrd39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001172Ankyrin repeat domain-containing protein 39; Belongs to the ANKRD39 family.
Pcnt protein networkhttps://string-db.org/network/10090.ENSMUSP00000001179Pericentrin; Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, togeth [...]
Col6a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001181Collagen alpha-2(VI) chain; Collagen VI acts as a cell-binding protein.
Ftcd protein networkhttps://string-db.org/network/10090.ENSMUSP00000001183Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folat [...]
Mxd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001184Max dimerization protein 1; Transcriptional repressor. MAD binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MAD thus anta [...]
Gmcl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001185Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport.
Snrnp27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001186U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein; May play a role in mRNA splicing; Belongs to the SNUT3 family.
Ocrl protein networkhttps://string-db.org/network/10090.ENSMUSP00000001202Inositol polyphosphate 5-phosphatase OCRL; Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphat [...]
Sh3bp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001226SH3 domain-binding protein 1; GTPase activating protein (GAP) which specifically converts GTP-bound Rho-type GTPases including RAC1 and CDC42 in their inactive GDP-bound form. By specifically ina [...]
Agpat3 protein networkhttps://string-db.org/network/10090.ENSMUSP000000012401-acyl-sn-glycerol-3-phosphate acyltransferase gamma; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by i [...]
Gatd3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000001242Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial.
Rnf32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001247RING finger protein 32; May play a role in sperm formation.
Slc26a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001253Pendrin; Sodium-independent transporter of chloride and iodide.
Slc26a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001254Chloride anion exchanger; Chloride/bicarbonate exchanger. Mediates the efficient absorption of chloride ions in the colon, participating in fluid homeostasis. Plays a role in the chloride and bic [...]
Sema6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000001256Semaphorin-6B.
Uhrf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001258E3 ubiquitin-protein ligase UHRF1; Multidomain protein that acts as a key epigenetic regulator by bridging DNA methylation and chromatin modification. Specifically recognizes and binds hemimethyl [...]
Lsr protein networkhttps://string-db.org/network/10090.ENSMUSP00000001279Lipolysis-stimulated lipoprotein receptor; Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows [...]
Gramd1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000001280Protein Aster-A; Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). Contains unique domains for binding [...]
Ckb protein networkhttps://string-db.org/network/10090.ENSMUSP00000001304Creatine kinase B-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy tran [...]
Efnb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001319Ephrin-B2; Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithel [...]
Sp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001326Transcription factor Sp1; Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and reg [...]
Itgb7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001327Integrin beta-7; Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is involved in adhesive interactions of leukocytes. It is a receptor for fibronectin and recognizes one or [...]
Rrp15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001339RRP15-like protein.
Rnd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001347Rho-related GTP-binding protein RhoN; May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily (By similarity); Belongs to the small G [...]
Cnn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001384Calponin-1; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropom [...]
Fbxo9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001402F-box only protein 9; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradati [...]
Vps50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001412Syndetin; Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferri [...]
Apbb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001415Amyloid-beta A4 precursor protein-binding family B member 3; May modulate the internalization of amyloid-beta precursor protein.
Hars protein networkhttps://string-db.org/network/10090.ENSMUSP00000001416Histidine--tRNA ligase, cytoplasmic; Catalyzes the ATP-dependent ligation of histidine to the 3'- end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP). Play [...]
Zmat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001419Zinc finger matrin-type protein 2; Involved in pre-mRNA splicing as a component of the spliceosome.
Smg5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001451Protein SMG5; Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought provide a link to the mRNA de [...]
Cct3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001452T-complex protein 1 subunit gamma; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC comple [...]
Tmem79 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001456Transmembrane protein 79; Contributes to the epidermal integrity and skin barrier function. Plays a role in the lamellar granule (LG) secretory system and in the stratum corneum (SC) epithelial c [...]
Snd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001460Staphylococcal nuclease domain-containing protein 1; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs (By similarity). As part of its function in miRNA decay, re [...]
Kpnb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001479Importin subunit beta-1; Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in c [...]
Npepps protein networkhttps://string-db.org/network/10090.ENSMUSP00000001480Puromycin-sensitive aminopeptidase; Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regula [...]
Tbx21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001484T-box transcription factor TBX21; Lineage-defining transcription factor which initiates Th1 lineage development from naive Th precursor cells both by activating Th1 genetic programs and by repres [...]
Mrpl10 protein networkhttps://string-db.org/network/10090.ENSMUSP0000000148539S ribosomal protein L10, mitochondrial; Belongs to the universal ribosomal protein uL10 family.
Cideb protein networkhttps://string-db.org/network/10090.ENSMUSP00000001497Cell death activator CIDE-B; Activates apoptosis.
Cyp51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001507Lanosterol 14-alpha demethylase; A cytochrome P450 monooxygenase involved in sterol biosynthesis. Catalyzes 14-alpha demethylation of lanosterol and 24,25- dihydrolanosterol likely through sequen [...]
Tubb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001513Tubulin beta-6 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha ch [...]
Afg3l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001520AFG3-like protein 1; Putative ATP-dependent protease. Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteol [...]
Sost protein networkhttps://string-db.org/network/10090.ENSMUSP00000001534Sclerostin; Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation; Belongs to the sclerostin family.
Nkx2-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001536Homeobox protein Nkx-2.1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the mai [...]
Vwa5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000001544Von Willebrand factor A domain-containing protein 5A; May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is invo [...]
Col1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001547Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family.
Itfg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001559KICSTOR complex protein ITFG2; As part of the KICSTOR complex functions in the amino acid- sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 [...]
Tulp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001562Tubby-related protein 3; Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT- A) and is required for recruitment o [...]
Gtf2h4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001565General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotid [...]
Tubb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001566Tubulin beta-5 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha ch [...]
Flot1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001569Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
Ell2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001583RNA polymerase II elongation factor ELL2; Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription b [...]
Jup protein networkhttps://string-db.org/network/10090.ENSMUSP00000001592Junction plakoglobin; Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of [...]
Fkbp10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001595Peptidyl-prolyl cis-trans isomerase FKBP10; PPIases accelerate the folding of proteins during protein synthesis.
Klhl10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001599Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target p [...]
Nom1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001611Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus.
Fxr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001620Fragile X mental retardation syndrome-related protein 1; RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local tran [...]
Tnk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001626Non-receptor tyrosine-protein kinase TNK1; May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoiet [...]
Acap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001631Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1; GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins fr [...]
Bdkrb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001652B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 [...]
Ifrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001672Interferon-related developmental regulator 1; Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that at [...]
Stk38l protein networkhttps://string-db.org/network/10090.ENSMUSP00000001675Serine/threonine-protein kinase 38-like; Involved in the regulation of structural processes in differentiating and mature neuronal cells.
Hoxc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001699Homeobox protein Hox-C10; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posteri [...]
Hoxc13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001700Homeobox protein Hox-C13; Transcription factor which plays a role in hair follicle differentiation. Regulates FOXQ1 expression and that of other hair- specific genes.
Hoxc11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001701Homeobox protein Hox-C11; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posteri [...]
Hoxc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001703Homeobox protein Hox-C8; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Hoxc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001706Homeobox protein Hox-C9; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Hoxc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001709Homeobox protein Hox-C5; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Hoxc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001711Homeobox protein Hox-C6; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Cabin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001712Calcineurin-binding protein 1.
Gstt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001713Glutathione S-transferase theta-1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numer [...]
Gstt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001715Glutathione S-transferase theta-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Shows high activity towards 4-nitrobenzyl chloride (4 [...]
Ddt protein networkhttps://string-db.org/network/10090.ENSMUSP00000001716D-dopachrome decarboxylase; Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI); Belongs to the MIF family.
Tat protein networkhttps://string-db.org/network/10090.ENSMUSP00000001720Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate a [...]
Marveld3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001722MARVEL domain-containing protein 3.
Ddx18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001724ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
Eef1e1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001757Eukaryotic translation elongation factor 1 epsilon-1; Positive modulator of ATM response to DNA damage.
Akt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001780RAC-alpha serine/threonine-protein kinase; AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes includi [...]
Il16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001792Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyt [...]
Naglu protein networkhttps://string-db.org/network/10090.ENSMUSP00000001802Alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB).
Pabpc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001809Polyadenylate-binding protein 1; Binds the poly(A) tail of mRNA, including that of its own transcript, and regulates processes of mRNA metabolism such as pre-mRNA splicing and mRNA stability. Its [...]
Smo protein networkhttps://string-db.org/network/10090.ENSMUSP00000001812Smoothened homolog; G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its recepto [...]
Crnkl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001818Crooked neck-like protein 1; Involved in pre-mRNA splicing process.
Folh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001824Glutamate carboxypeptidase 2; Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides (By similarity). [...]
Chordc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001825Cysteine and histidine-rich domain-containing protein 1; Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play [...]
Rtcb protein networkhttps://string-db.org/network/10090.ENSMUSP00000001834RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-deri [...]
Pwp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001836Periodic tryptophan protein 1 homolog; Chromatin-associated factor that regulates transcription (By similarity). Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcrip [...]
Capns1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001845Calpain small subunit 1; Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal [...]
Slc7a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001854Asc-type amino acid transporter 1; Sodium-independent, high affinity transport of small neutral D- and L-amino acids and amino acid-related compounds. May play a role in the modulation of glutama [...]
Hoxd13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001872Homeobox protein Hox-D13; Sequence-specific transcription factor that binds gene promoters and activates their transcription. Part of a developmental regulatory system that provides cells with sp [...]
Hoxd12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001878Homeobox protein Hox-D12; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posteri [...]
Clpb protein networkhttps://string-db.org/network/10090.ENSMUSP00000001884Caseinolytic peptidase B protein homolog; May function as a regulatory ATPase and be related to secretion/protein trafficking process; Belongs to the ClpA/ClpB family.
Zdhhc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001900Probable palmitoyltransferase ZDHHC4; Belongs to the DHHC palmitoyltransferase family.
Aif1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000001920Allograft inflammatory factor 1-like; Actin-binding protein that promotes actin bundling. May neither bind calcium nor depend on calcium for function (By similarity).
Cpa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001921Mast cell carboxypeptidase A.
Ltbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001927Latent-transforming growth factor beta-binding protein 1; Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent [...]
Tollip protein networkhttps://string-db.org/network/10090.ENSMUSP00000001950Toll-interacting protein; Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits [...]
Ace protein networkhttps://string-db.org/network/10090.ENSMUSP00000001963Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensi [...]
Kcnh6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001965Potassium Voltage-gated channel, subfamily H (Eag-related), member 6.
Trmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001974tRNA (guanine(26)-N(2))-dimethyltransferase; Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups. Belongs to the class I [...]
Nacc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001975Nucleus accumbens-associated protein 1; Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Cont [...]
Uba1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000001989Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquit [...]
Vsig2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002008V-set and immunoglobulin domain-containing protein 2.
Esam protein networkhttps://string-db.org/network/10090.ENSMUSP00000002011Endothelial cell-selective adhesion molecule; Can mediate aggregation most likely through a homophilic molecular interaction.
Spa17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002013Sperm surface protein Sp17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohyd [...]
Emd protein networkhttps://string-db.org/network/10090.ENSMUSP00000002029Emerin; Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibi [...]
Ccdc47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002043Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD [...]
Map3k3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002044Mitogen-activated protein kinase kinase kinase 3; Component of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators.
Taco1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002048Translational activator of cytochrome c oxidase 1; Acts as a translational activator of mitochondrially-encoded cytochrome c oxidase 1; Belongs to the TACO1 family.
Npas1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002053Neuronal PAS domain-containing protein 1; May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulat [...]
Ap4e1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002063AP-4 complex subunit epsilon-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. Th [...]
Blvra protein networkhttps://string-db.org/network/10090.ENSMUSP00000002064Biliverdin reductase A; Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor; Belongs to the Gfo [...]
Plxnb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002079Plexin-B3; Receptor for SEMA5A that plays a role in axon guidance, invasive growth and cell migration. Stimulates neurite outgrowth and mediates Ca(2+)/Mg(2+)-dependent cell aggregation. In gliom [...]
Pdzd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002080PDZ domain-containing protein 4.
Srpk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002081SRSF protein kinase 3; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, know [...]
Abcd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002084ATP-binding cassette sub-family D member 1; Plays a role in the transport of free very-long-chain fatty acids (VLCFAs) as well as their CoA-esters across the peroxisomal membrane by acting as an [...]
Pnck protein networkhttps://string-db.org/network/10090.ENSMUSP00000002087Calcium/calmodulin-dependent protein kinase type 1B; Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN [...]
Bcap31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002091B-cell receptor-associated protein 31; Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER [...]
Kmt2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000002095Histone-lysine N-methyltransferase 2A; Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein com [...]
Ift46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002099Intraflagellar transport protein 46 homolog; Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance an [...]
Tmem25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002100Transmembrane protein 25; In neurons, modulates the degradation of NMDA receptor GRIN2B subunit. Plays a role in the regulation of neuronal excitability.
Cd3g protein networkhttps://string-db.org/network/10090.ENSMUSP00000002101T-cell surface glycoprotein CD3 gamma chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cel [...]
Trappc6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000002112Trafficking protein particle complex subunit 6A; May play a role in vesicular transport during the biogenesis of melanosomes.
Supt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002121Transcription elongation factor SPT6; Transcription elongation factor which binds histone H3 and plays a key role in the regulation of transcription elongation and mRNA processing. Enhances the t [...]
Sdf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002133Stromal cell-derived factor 2.
Bbc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002152Bcl-2-binding component 3; Essential mediator of p53/TP53-dependent and p53/TP53- independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP5 [...]
Acp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002172Lysosomal acid phosphatase.
Spi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002180Transcription factor PU.1; Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA- 3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be sp [...]
Sf3a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002198Splicing factor 3A subunit 1; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of [...]
Clgn protein networkhttps://string-db.org/network/10090.ENSMUSP00000002259Calmegin; Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zo [...]
Napsa protein networkhttps://string-db.org/network/10090.ENSMUSP00000002274Napsin-A; May be involved in processing of pneumocyte surfactant precursors.
Vrk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002275Inactive serine/threonine-protein kinase VRK3; Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specifically dephosphorylates and inactivates ERK in t [...]
Smg9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002280Protein SMG9; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SM [...]
Plaur protein networkhttps://string-db.org/network/10090.ENSMUSP00000002284Urokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-inde [...]
Uchl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002289Ubiquitin carboxyl-terminal hydrolase isozyme L3; Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. T [...]
Paxip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002291PAX-interacting protein 1; Involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes such as the MLL2/MLL3 complex. Plays a role in early [...]
Rmnd5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000002292E3 ubiquitin-protein ligase RMND5A; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteas [...]
Ppm1j protein networkhttps://string-db.org/network/10090.ENSMUSP00000002298Protein phosphatase 1J; Belongs to the PP2C family.
Rhoc protein networkhttps://string-db.org/network/10090.ENSMUSP00000002303Rho-related GTP-binding protein RhoC; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule [...]
Kdm7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000002305Lysine-specific demethylase 7A; Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 [...]
Ppard protein networkhttps://string-db.org/network/10090.ENSMUSP00000002320Peroxisome proliferator-activated receptor delta; Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference [...]
Def6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002327Differentially expressed in FDCP 6; Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and [...]
Zim1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002336Zinc finger, imprinted 1.
Ciao3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002350Cytosolic iron-sulfur assembly component 3; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster in [...]
Angptl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002360Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabol [...]
Cd320 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002379CD320 antigen; Receptor for transcobalamin saturated with cobalamin (TCbl). Plays an important role in cobalamin uptake. Plasma membrane protein that is expressed on follicular dendritic cells (F [...]
Rec8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002395Meiotic recombination protein REC8 homolog; Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin duri [...]
Gmpr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002397GMP reductase 2; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, a [...]
Mdp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002400Magnesium-dependent phosphatase 1; Magnesium-dependent phosphatase which may act as a tyrosine phosphatase.
Dhrs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002403Dehydrogenase/reductase SDR family member 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Ncan protein networkhttps://string-db.org/network/10090.ENSMUSP00000002412Neurocan core protein; May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N- CAM). Chondroitin sulfate proteoglycan; bin [...]
Tmem161a protein networkhttps://string-db.org/network/10090.ENSMUSP00000002413Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity).
Borcs8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002418BLOC-1-related complex subunit 8; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BO [...]
Snx9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002436Sorting nexin-9; Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. [...]
Rfx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002444DNA-binding protein RFX2; Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such a [...]
Ranbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002445Ran-binding protein 3; Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In [...]
Ndufa11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002452NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involve [...]
Nt5c1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000002456Cytosolic 5'-nucleotidase 1B; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels.
Bmp8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000002457Bone morphogenetic protein 8B; Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation [...]
Nr2f6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002466Nuclear receptor subfamily 2 group F member 6; Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5 [...]
Ocel1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002469Occludin/ELL domain-containing protein 1; Belongs to the ELL/occludin family.
Babam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002473BRISC and BRCA1-A complex member 1; Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to t [...]
Braf protein networkhttps://string-db.org/network/10090.ENSMUSP00000002487Serine/threonine-protein kinase B-raf; Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Phosphorylates MAP2K1, and thereby activates the MAP kinase signal [...]
Meis3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002495Homeobox protein Meis3; Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG [...]
Hltf protein networkhttps://string-db.org/network/10090.ENSMUSP00000002502Helicase-like transcription factor; Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity. This activity may be required for trans [...]
Tle5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002518TLE family member 5; Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and ma [...]
Prpf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002529Pre-mRNA-processing factor 6; Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced tra [...]
Snrpd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002551Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, [...]
Slc9a3r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002572Na(+)/H(+) exchange regulatory cofactor NHE-RF2; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the acti [...]
Tiam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002588T-lymphoma invasion and metastasis-inducing protein 1; Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimu [...]
Scrib protein networkhttps://string-db.org/network/10090.ENSMUSP00000002603Protein scribble homolog; Scaffold protein involved in different aspects of polarized cells differentiation regulating epithelial and neuronal morphogenesis. Most probably functions in the establ [...]
Uck1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002625Uridine-cytidine kinase 1; Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use [...]
Scin protein networkhttps://string-db.org/network/10090.ENSMUSP00000002640Adseverin; Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. [...]
Mien1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002655Migration and invasion enhancer 1; Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through contr [...]
Pon1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002663Serum paraoxonase/arylesterase 1; Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactone [...]
Axl protein networkhttps://string-db.org/network/10090.ENSMUSP00000002677Tyrosine-protein kinase receptor UFO; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating [...]
Tgfb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002678Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) ch [...]
Ccdc97 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002683Coiled-coil domain-containing protein 97.
Akap8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002699A-kinase anchor protein 8; Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II). Acts as an anchor for a PKA-signaling complex onto mito [...]
Shh protein networkhttps://string-db.org/network/10090.ENSMUSP00000002708Sonic hedgehog protein N-product; [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity. Both ac [...]
Pdcd2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000002710Programmed cell death protein 2-like; Over-expression suppresses AP1, CREB, NFAT, and NF-kB transcriptional activation, and delays cell cycle progression at S phase.
Gtf2f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002733General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration w [...]
Clpp protein networkhttps://string-db.org/network/10090.ENSMUSP00000002735ATP-dependent Clp protease proteolytic subunit, mitochondrial; Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase acti [...]
Alkbh7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002737Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial; May function as protein hydroxylase; can catalyze auto- hydroxylation at Leu-110 (in vitro), but this activity may be due [...]
Pspn protein networkhttps://string-db.org/network/10090.ENSMUSP00000002740Persephin; Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.
Cox16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002757Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes [...]
Prkd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002765Serine/threonine-protein kinase D1; Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in [...]
Cse1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000002790Exportin-2; Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In th [...]
Naa20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002805N-alpha-acetyltransferase 20; Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met- [...]
Prkra protein networkhttps://string-db.org/network/10090.ENSMUSP00000002808Interferon-inducible double-stranded RNA-dependent protein kinase activator A; Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does [...]
Fkbp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002809Peptidyl-prolyl cis-trans isomerase FKBP7; PPIases accelerate the folding of proteins during protein synthesis.
Ykt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002818Synaptobrevin homolog YKT6; Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic [...]
Baz1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000002825Tyrosine-protein kinase BAZ1B; Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phospho [...]
Tmed5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002837Transmembrane emp24 domain-containing protein 5; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; invol [...]
Ppp2r5d protein networkhttps://string-db.org/network/10090.ENSMUSP00000002839Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of [...]
Pex6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002840Peroxisome assembly factor 2; Involved in peroxisome biosynthesis. Required for stability of the PTS1 receptor. Probably required for protein import into peroxisomes. Anchored by PEX26 to peroxis [...]
Mrpl2 protein networkhttps://string-db.org/network/10090.ENSMUSP0000000284439S ribosomal protein L2, mitochondrial; Belongs to the universal ribosomal protein uL2 family.
Gnmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000002846Glycine N-methyltransferase; Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocyst [...]
Grin2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000002848Glutamate receptor ionotropic, NMDA 2D; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sens [...]
Abcc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002850Multidrug resistance-associated protein 6; May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Belongs to the ABC tran [...]
Kdelr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002855ER lumen protein-retaining receptor 1; Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Gol [...]
Btbd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002880BTB/POZ domain-containing protein 6; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex (By similarity). Involved in late neuronal development and muscle formation (By similarity).
Sfrp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002883Secreted frizzled-related sequence protein 4; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulatin [...]
Epdr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002885Mammalian ependymin-related protein 1; Binds anionic lipids and gangliosides at acidic pH. Belongs to the ependymin family.
Flii protein networkhttps://string-db.org/network/10090.ENSMUSP00000002889Protein flightless-1 homolog; May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in es [...]
Top3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000002891DNA topoisomerase 3-alpha; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the D [...]
Qtrt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002902Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at p [...]
Chaf1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000002914Chromatin assembly factor 1 subunit A; Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto repl [...]
Adprh protein networkhttps://string-db.org/network/10090.ENSMUSP00000002923[Protein ADP-ribosylarginine] hydrolase; Specifically acts as a arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins.
Tmem39a protein networkhttps://string-db.org/network/10090.ENSMUSP00000002924Transmembrane protein 39A; Belongs to the TMEM39 family.
Timmdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002925Complex I assembly factor TIMMDC1, mitochondrial; Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Participates in constructing [...]
Pla1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000002926Phospholipase A1 member A; Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposome [...]
Il17ra protein networkhttps://string-db.org/network/10090.ENSMUSP00000002976Interleukin-17 receptor A; Receptor for IL17A. Receptor for IL17F. Binds to IL17A with higher affinity than to IL17F. Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17 [...]
Lamb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002979Laminin subunit beta-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development [...]
Arrdc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000002989Arrestin domain-containing protein 2.
Tbxas1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003017Thromboxane-A synthase; Belongs to the cytochrome P450 family.
Map2k7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003027Dual specificity mitogen-activated protein kinase kinase 7; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component [...]
Timm44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003029Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inn [...]
Disp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003035Protein dispatched homolog 1; Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effect [...]
Ap2a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003038AP-2 complex subunit alpha-2; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathw [...]
Pnkp protein networkhttps://string-db.org/network/10090.ENSMUSP00000003044Bifunctional polynucleotide phosphatase/kinase; Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) path [...]
Med25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003049Mediator of RNA polymerase II transcription subunit 25; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Bcam protein networkhttps://string-db.org/network/10090.ENSMUSP00000003061Basal cell adhesion molecule; Laminin alpha-5 receptor. May mediate intracellular signaling (By similarity).
Apoc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003071Apolipoprotein C-IV; May participate in lipoprotein metabolism.
Cyp2f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003100Cytochrome P450 2F2; Involved in the regio- and stereoselective transformation of naphthalene to trans-1R-hydroxy-2R-glutathionyl-1,2-dihydronaphthalene in the presence of glutathione and glutath [...]
Ap1m1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003117AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate t [...]
Rab8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000003121Ras-related protein Rab-8A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle bet [...]
Fam32a protein networkhttps://string-db.org/network/10090.ENSMUSP00000003123Protein FAM32A; May induce G2 arrest and apoptosis (By similarity). May also increase cell sensitivity to apoptotic stimuli (By similarity). In cell lines, may play a role in the inhibition of an [...]
Elf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003135ETS-related transcription factor Elf-3; Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with [...]
Cyp2c29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003137Cytochrome P450 2C29; Metabolizes arachidonic acid to produce 14,15-cis- epoxyeicosatrienoic acid (EET).
Stk11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003152Serine/threonine-protein kinase STK11; Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in [...]
Efna2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003154Ephrin-A2; Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial [...]
Ppp5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000003183Serine/threonine-protein phosphatase 5; Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1 [...]
Lipe protein networkhttps://string-db.org/network/10090.ENSMUSP00000003207Hormone-sensitive lipase; In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters [...]
Foxj2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003238Forkhead box protein J2; Transcriptional activator. Able to bind to two different type of DNA binding sites.
Sh3gl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003268Endophilin-A2; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
Ebi3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003274Interleukin-27 subunit beta; Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that [...]
Irf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003284Interferon regulatory factor 3; Key transcriptional regulator of type I interferon (IFN)- dependent immune responses which plays a critical role in the innate immune response against DNA and RNA [...]
Bcl2l12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003290BCL2-like 12 (proline-rich).
Ranbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003310E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F [...]
Edar protein networkhttps://string-db.org/network/10090.ENSMUSP00000003312Tumor necrosis factor receptor superfamily member EDAR; Receptor for EDA isoform TAA, but not for EDA isoform TA-2 (By similarity). May mediate the activation of NF-kappa-B and JNK. May promote c [...]
Grk5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003313G protein-coupled receptor kinase 5; Serine/threonine kinase that phosphorylates preferentially the activated forms of a variety of G-protein-coupled receptors (GPCRs). Such receptor phosphorylat [...]
Abcf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003319ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B.
Eif2b5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003320Translation initiation factor eIF-2B subunit epsilon; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B gamma/epsilon subunits family.
Car11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003360Carbonic anhydrase-related protein 11; Does not have a catalytic activity; Belongs to the alpha-carbonic anhydrase family.
Plag1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003369Zinc finger protein PLAG1; Transcription factor whose activation results in up- regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultur [...]
Hck protein networkhttps://string-db.org/network/10090.ENSMUSP00000003370Tyrosine-protein kinase HCK; Non-receptor tyrosine-protein kinase found in hematopoietic cells that transmits signals from cell surface receptors and plays an important role in the regulation of [...]
Mrpl4 protein networkhttps://string-db.org/network/10090.ENSMUSP0000000338639S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL4 family.
Btbd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003434BTB (POZ) domain-containing 2.
Abhd17a protein networkhttps://string-db.org/network/10090.ENSMUSP00000003436Alpha/beta hydrolase domain-containing protein 17A; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards NRAS. Has depalmitoylating activity [...]
Mob3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000003438MOB kinase activator 3A; May regulate the activity of kinases.
Ccdc65 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003444Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the dis [...]
Fkbp11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003445Peptidyl-prolyl cis-trans isomerase FKBP11; PPIases accelerate the folding of proteins during protein synthesis; Belongs to the FKBP-type PPIase family.
Ddx23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003450DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.
Rnd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003451Rho-related GTP-binding protein Rho6; Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac [...]
Myo1g protein networkhttps://string-db.org/network/10090.ENSMUSP00000003459Unconventional myosin-Ig; Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T-cell migration. Unconventional myosins are actin-bas [...]
Grik5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003468Glutamate receptor ionotropic, kainate 5; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Gl [...]
Cd79a protein networkhttps://string-db.org/network/10090.ENSMUSP00000003469B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell [...]
Elavl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003501ELAV-like protein 3; RNA-binding protein that binds to AU-rich element (ARE) sequences of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3. May be involved in neuronal dif [...]
St8sia6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003509Alpha-2,8-sialyltransferase 8F; Prefers O-glycans to N-glycans or glycolipids as acceptor substrates. The minimal acceptor substrate is the NeuAc-alpha-2,3(6)- Gal sequence at the non-reducing en [...]
Fcgrt protein networkhttps://string-db.org/network/10090.ENSMUSP00000003512IgG receptor FcRn large subunit p51; Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and med [...]
Nosip protein networkhttps://string-db.org/network/10090.ENSMUSP00000003513Nitric oxide synthase-interacting protein; E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye and the face. Catalyzes monoubiquitination of serine/thre [...]
Rps11 protein networkhttps://string-db.org/network/10090.ENSMUSP0000000352140S ribosomal protein S11.
Paf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003529RNA polymerase II-associated factor 1 homolog; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of deve [...]
Med29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003536Mediator of RNA polymerase II transcription subunit 29; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Ncstn protein networkhttps://string-db.org/network/10090.ENSMUSP00000003550Nicastrin; Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amylo [...]
Casq1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003554Calsequestrin-1; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic r [...]
Phyhip protein networkhttps://string-db.org/network/10090.ENSMUSP00000003561Phytanoyl-CoA hydroxylase-interacting protein; Its interaction with PHYH suggests a role in the development of the central system.
Inmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000003569Indolethylamine N-methyltransferase; Catalyzes the N-methylation of tryptamine and structurally related compounds (By similarity). Functions as thioether S- methyltransferase and is active with a [...]
Gars protein networkhttps://string-db.org/network/10090.ENSMUSP00000003572Glycine--tRNA ligase; Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenos [...]
Cyp4f18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003574Cytochrome P450 4F3; A cytochrome P450 monooxygenase involved in the metabolism of the proinflammatory lipid mediator leukotriene B4 (LTB4). Hydroxylates at the omega-1 and omega-2 positions LTB4 [...]
Tpm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003575Tropomyosin alpha-4 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebra [...]
Psg18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003597Pregnancy-specific glycoprotein 18.
Pcdhgb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003599Protocadherin gamma subfamily B, 6.
Prodh protein networkhttps://string-db.org/network/10090.ENSMUSP00000003620Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate.
Ess2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003621Splicing factor ESS-2 homolog; May be involved in pre-mRNA splicing.
Slc25a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003622Tricarboxylate transport protein, mitochondrial; Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate. Also able to mediate the exchange of citrate for iso [...]
Ier3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003635Radiation-inducible immediate-early gene IEX-1; May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK [...]
Fosb protein networkhttps://string-db.org/network/10090.ENSMUSP00000003640Protein fosB; FosB interacts with Jun proteins enhancing their DNA binding activity; Belongs to the bZIP family. Fos subfamily.
Klc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003642Kinesin light chain 4; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chai [...]
Ercc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003645DNA excision repair protein ERCC-1; Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX [...]
As3mt protein networkhttps://string-db.org/network/10090.ENSMUSP00000003655Arsenite methyltransferase; Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylars [...]
Comp protein networkhttps://string-db.org/network/10090.ENSMUSP00000003659Cartilage oligomeric matrix protein; May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. C [...]
Rnf215 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003677RING finger protein 215.
Sec14l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003681SEC14-like protein 2; Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also bin [...]
Tgfb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003687Transforming growth factor beta-3 proprotein; Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) ch [...]
Aven protein networkhttps://string-db.org/network/10090.ENSMUSP00000003705Cell death regulator Aven; Protects against apoptosis mediated by Apaf-1.
Abcb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003717Phosphatidylcholine translocator ABCB4; Energy-dependent phospholipid efflux translocator that acts as a positive regulator of biliary lipid secretion. Functions as a floppase that translocates s [...]
Crot protein networkhttps://string-db.org/network/10090.ENSMUSP00000003720Peroxisomal carnitine O-octanoyltransferase; Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate.
Brd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003726Bromodomain-containing protein 4; Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transc [...]
Calb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003754Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons.
Ciao1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003759Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of [...]
Has1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003762Hyaluronan synthase 1; Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most ex [...]
Gdf15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003808Growth/differentiation factor 15; Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor, GFRAL, and activates GFRAL- [...]
Insig2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003818Insulin-induced gene 2 protein; Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding protein [...]
Htr3a protein networkhttps://string-db.org/network/10090.ENSMUSP000000038265-hydroxytryptamine receptor 3A; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mit [...]
Man1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000003843Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce [...]
Itpkc protein networkhttps://string-db.org/network/10090.ENSMUSP00000003850Inositol-trisphosphate 3-kinase C; Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate.
Shkbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003857SH3KBP1-binding protein 1; Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits [...]
Mxi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003870Max-interacting protein 1; Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus ant [...]
Brd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003876Bromodomain-containing protein 8; May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Stimulates transcriptional activation by AR/DHTR, ESR1/NR [...]
Ece2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003898Endothelin-converting enzyme 2; Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, p [...]
Farsa protein networkhttps://string-db.org/network/10090.ENSMUSP00000003906Phenylalanine--tRNA ligase alpha subunit.
Gcdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000003907Glutaryl-CoA dehydrogenase, mitochondrial; Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L- hydroxylysine, and L-trypto [...]
Dnase2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000003910Deoxyribonuclease-2-alpha; Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during deve [...]
Calr protein networkhttps://string-db.org/network/10090.ENSMUSP00000003912Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts [...]
Nob1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003946RNA-binding protein NOB1; May play a role in mRNA degradation (By similarity). Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (By similari [...]
Nqo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003947NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in b [...]
Ppfia3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003961Liprin-alpha-3; May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their inter [...]
Gys1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000003964Glycogen [starch] synthase, muscle; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Belongs to the glycosyltransferase 3 family.
Lin7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000003971Protein lin-7 homolog B; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated mu [...]
Il7r protein networkhttps://string-db.org/network/10090.ENSMUSP00000003981Interleukin-7 receptor subunit alpha; Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
Efnb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004036Ephrin-B3; Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithel [...]
Mmd protein networkhttps://string-db.org/network/10090.ENSMUSP00000004050Monocyte to macrophage differentiation factor; Involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion; Belongs to the ADIPOR family.
Hlf protein networkhttps://string-db.org/network/10090.ENSMUSP00000004051Hepatic leukemia factor; Belongs to the bZIP family. PAR subfamily.
Kpna1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004054Importin subunit alpha-5; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or biparti [...]
Fam162a protein networkhttps://string-db.org/network/10090.ENSMUSP00000004057Protein FAM162A; Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells [...]
Grm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004076Metabotropic glutamate receptor 3; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G protein [...]
Ssbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004094Single-stranded DNA-binding protein 2.
Fancl protein networkhttps://string-db.org/network/10090.ENSMUSP00000004120E3 ubiquitin-protein ligase FANCL; Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimul [...]
Brinp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004133BMP/retinoic acid-inducible neural-specific protein 2; Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition; Belongs to the BRINP family.
Gstm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004134Glutathione S-transferase Mu 5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family.
Gstm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004136Glutathione S-transferase Mu 3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family.
Gstm7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004137Glutathione S-transferase Mu 7; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family.
Gstm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004140Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Map3k11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004156Mitogen-activated protein kinase kinase kinase 11; Activates the JUN N-terminal pathway. Required for serum- stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), [...]
Hmox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004172Heme oxygenase 2; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiologic [...]
Cdip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004173Cell death-inducing p53-target protein 1; Acts as an important p53/TP53-apoptotic effector. Regulates TNF-alpha-mediated apoptosis in a p53/TP53-dependent manner (By similarity); Belongs to the C [...]
Cwc15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004200Spliceosome-associated protein CWC15 homolog; Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome an [...]
Col5a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004201Collagen type V alpha 3 chain.
Dnmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004202DNA (cytosine-5)-methyltransferase 1; Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern i [...]
Ppan protein networkhttps://string-db.org/network/10090.ENSMUSP00000004203Suppressor of SWI4 1 homolog; May have a role in cell growth.
Eif3g protein networkhttps://string-db.org/network/10090.ENSMUSP00000004206Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiatio [...]
Angptl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004208Angiopoietin-related protein 2; Induces sprouting in endothelial cells through an autocrine and paracrine action.
Hira protein networkhttps://string-db.org/network/10090.ENSMUSP00000004222Protein HIRA; Required for the periodic repression of histone gene transcription during the cell cycle (By similarity). Cooperates with ASF1A to promote replication-independent chromatin assembly [...]
Adh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004232Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily.
Dyrk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004281Dual specificity tyrosine-phosphorylation-regulated kinase 2; Serine/threonine-protein kinase involved in the regulation of the mitotic cell cycle, cell proliferation, apoptosis, organization of [...]
Kifc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004294Kinesin-like protein KIFC2; May play a role in microtubule-dependent retrograde axonal transport. May function as the motor for the transport of multivesicular body (MVB)-like organelles in dendr [...]
Plxna3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004326Plexin-A3; Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous [...]
G6pdx protein networkhttps://string-db.org/network/10090.ENSMUSP00000004327Glucose-6-phosphate 1-dehydrogenase X; Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shu [...]
Ikbkg protein networkhttps://string-db.org/network/10090.ENSMUSP00000004330NF-kappa-B essential modulator; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and u [...]
Wars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004343Tryptophan--tRNA ligase, mitochondrial; Mitochondrial aminoacyl-tRNA synthetase that activate and transfer the amino acids to their corresponding tRNAs during the translation of mitochondrial gen [...]
Phb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004375Prohibitin-2; Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator t [...]
Ptpn6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004377Tyrosine-protein phosphatase non-receptor type 6; Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with ot [...]
Eno2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004378Gamma-enolase; Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium- dependent manner, to cultured neocortical neurons [...]
Emg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004379Ribosomal RNA small subunit methyltransferase NEP1; S-adenosyl-L-methionine-dependent pseudouridine N(1)- methyltransferase that methylates pseudouridine at position 1248 (Psi1248) in 18S rRNA. I [...]
Lpcat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004381Lysophospholipid acyltransferase 5; Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-gl [...]
Grcc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004389Protein C10; In brain, may be required for corpus callosum development. Belongs to the UPF0456 family.
Atp6v1f protein networkhttps://string-db.org/network/10090.ENSMUSP00000004396V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracell [...]
Clcn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004430H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, [...]
Gpx6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004453Glutathione peroxidase 6; Belongs to the glutathione peroxidase family.
Utp20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004470Small subunit processome component 20 homolog; Involved in 18S pre-rRNA processing. Associates with U3 snoRNA (By similarity).
Spic protein networkhttps://string-db.org/network/10090.ENSMUSP00000004473Transcription factor Spi-C; Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-r [...]
Sst protein networkhttps://string-db.org/network/10090.ENSMUSP00000004480Somatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs gh [...]
Sin3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000004494Paired amphipathic helix protein Sin3b; Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX he [...]
Npc1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004505NPC1-like intracellular cholesterol transporter 1; Plays a major role in cholesterol homeostasis. Is critical for the uptake of both phytosterol and cholesterol across the plasma membrane of the [...]
Ddx56 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004507Probable ATP-dependent RNA helicase DDX56; May play a role in later stages of the processing of the pre- ribosomal particles leading to mature 60S ribosomal subunits. Has intrinsic ATPase activit [...]
Tmed4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004508Transmembrane emp24 domain-containing protein 4; Involved in vesicular protein trafficking, mainly in the early secretory pathway. Involved in the maintenance of the Golgi apparatus. Appears to p [...]
Bid protein networkhttps://string-db.org/network/10090.ENSMUSP00000004560BH3-interacting domain death agonist p11; Induces caspases and apoptosis. Counters the protective effect of Bcl-2. The major proteolytic product p15 BID allows the release of cytochrome c.
Ralb protein networkhttps://string-db.org/network/10090.ENSMUSP00000004565Ras-related protein Ral-B; Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane [...]
Tbccd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004576TBCC domain-containing protein 1; Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration; Belongs to the TBCC family.
Clec11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000004587C-type lectin domain family 11 member A; Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts. Important for repair and maintenance of adult [...]
Zfp110 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004614Neurotrophin receptor-interacting factor 1; Transcription regulator involved in NGFR/p75(NTR)-mediated apoptosis. Essential component of the NGFR/p75(NTR) apoptotic pathway: upon ligand-binding a [...]
Gab2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004622GRB2-associated-binding protein 2; Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate mu [...]
Coro1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000004646Coronin-1C; Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1. Increases the presence of activated RAC1 at the leading edge of migrating cells. [...]
Psg17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004655Pregnancy-specific glycoprotein 17.
Psg19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004657Pregnancy-specific glycoprotein 19.
Ndrg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004673Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor s [...]
Mcoln1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004683Mucolipin-1; Nonselective cation channel probably playing a role in the regulation of membrane trafficking events and of metal homeostasis. Proposed to play a major role in Ca(2+) release from la [...]
Arhgef18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004684Rho guanine nucleotide exchange factor 18; Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. May play a role in actin cytoskeleton reorganization in different tissues since its a [...]
Pex11g protein networkhttps://string-db.org/network/10090.ENSMUSP00000004686Peroxisomal membrane protein 11C; Promotes membrane protrusion and elongation on the peroxisomal surface.
Mospd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004715Motile sperm domain-containing protein 2; Promotes migration of primary monocytes and neutrophils, in response to various chemokines.
Cd33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004728Myeloid cell surface antigen CD33; Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state [...]
Etfb protein networkhttps://string-db.org/network/10090.ENSMUSP00000004729Electron transfer flavoprotein subunit beta; Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glut [...]
Lim2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004732Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for cal [...]
Wwox protein networkhttps://string-db.org/network/10090.ENSMUSP00000004756WW domain-containing oxidoreductase; Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-indu [...]
Tyr protein networkhttps://string-db.org/network/10090.ENSMUSP00000004770Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the [...]
Aqp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004774Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the di [...]
Cnn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004784Calponin-2; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropom [...]
Polr2e protein networkhttps://string-db.org/network/10090.ENSMUSP00000004786DNA-directed RNA polymerases I, II, and III subunit RPABC1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Com [...]
Cd244a protein networkhttps://string-db.org/network/10090.ENSMUSP00000004829Natural killer cell receptor 2B4; Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-c [...]
Mtfp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004868Mitochondrial fission process protein 1; Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function leads to apoptosis (By similarity). Belongs to the MTFP1 [...]
Eif2b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004910Translation initiation factor eIF-2B subunit beta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family.
Pgf protein networkhttps://string-db.org/network/10090.ENSMUSP00000004913Placenta growth factor; Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Also promotes cell [...]
Ulk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004920Serine/threonine-protein kinase ULK2; Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the format [...]
Ccl24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004936C-C motif chemokine 24; Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Binds to CCR3 (By [...]
Tmed11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004943Transmembrane emp24 domain-containing protein 11; Part of a complex whose function is to bind Ca(2+) to the ER membrane and thereby regulate the retention of ER resident proteins. Belongs to the [...]
Traf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004949TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, I [...]
Prpsap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004955Phosphoribosyl pyrophosphate synthase-associated protein 2; Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis; Belongs to the ribose-phosphate pyrophosphokinase [...]
Grap protein networkhttps://string-db.org/network/10090.ENSMUSP00000004959GRB2-related adapter protein; Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. Plays a role in the inner ear and in hearing; Belongs to the GRB2/sem-5/ [...]
Chmp2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000004965Charged multivesicular body protein 2b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation [...]
Plod3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004968Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3; Multifunctional enzyme that catalyzes a series of post- translational modifications on Lys residues in procollagen. Pla [...]
Brpf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004985Bromodomain and PHD finger-containing, 3.
Mapk14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004990Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an [...]
Pax3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000004994Paired box protein Pax-3; Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, act [...]
Lbr protein networkhttps://string-db.org/network/10090.ENSMUSP00000005003Delta(14)-sterol reductase LBR; Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis. Plays a critical role in m [...]
Hapln2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005014Hyaluronan and proteoglycan link protein 2; Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central [...]
Prcc protein networkhttps://string-db.org/network/10090.ENSMUSP00000005015Papillary Renal Cell carcinoma (Translocation-associated).
Rrnad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005016Protein RRNAD1; Belongs to the RRNAD1 family.
Hdgf protein networkhttps://string-db.org/network/10090.ENSMUSP00000005017Hepatoma-derived growth factor; Acts as a transcriptional repressor (By similarity). Has mitogenic activity for fibroblasts (By similarity). Heparin-binding protein (By similarity).
Crabp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005019Cellular retinoic acid-binding protein 2; Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
Tmem242 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005053Transmembrane protein 242; Belongs to the TMEM242 family.
Thop1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005057Thimet oligopeptidase; Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor prote [...]
Pias4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005064E3 SUMO-protein ligase PIAS4; Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Pla [...]
Map2k1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005066Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracel [...]
Sgta protein networkhttps://string-db.org/network/10090.ENSMUSP00000005067Small glutamine-rich tetratricopeptide repeat-containing protein alpha; Co-chaperone that binds misfolded and hydrophobic patches- containing client proteins in the cytosol. Mediates their target [...]
Nmrk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005069Nicotinamide riboside kinase 2; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucl [...]
Zp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005073Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and [...]
Hspb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005077Heat shock protein beta-1; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Plays a role in stress resistan [...]
Nfe2l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005103Nuclear factor erythroid 2-related factor 3; Activates erythroid-specific, globin gene expression; Belongs to the bZIP family. CNC subfamily.
Kdm5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000005108Lysine-specific demethylase 5A; Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', [...]
Fxyd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005114FXYD domain-containing ion transport regulator 4.
Prkacb protein networkhttps://string-db.org/network/10090.ENSMUSP00000005164cAMP-dependent protein kinase catalytic subunit beta; Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell pr [...]
Sgsh protein networkhttps://string-db.org/network/10090.ENSMUSP00000005173N-sulfoglucosamine sulfohydrolase (sulfamidase).
Cstb protein networkhttps://string-db.org/network/10090.ENSMUSP00000005185Cystatin-B; This is an intracellular thiol proteinase inhibitor.
Sh2b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005188SH2B adapter protein 2; Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways. May be involved in coupling from immunoreceptor to Ras [...]
Cd44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005218CD44 antigen; Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Particip [...]
Eif2ak4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005233eIF-2-alpha kinase GCN2; Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2- alpha/EIF2S1) on 'Ser-52' in response [...]
Wdr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005234WD repeat-containing protein 1; Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (By similarity). Enhances cofilin-mediated actin severing. Involved in cytok [...]
Ccn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005255CCN family member 4; Downstream regulator in the Wnt/Frizzled-signaling pathway (By similarity). Associated with cell survival. Adheres to skin and melanoma fibroblasts (By similarity). In vitro [...]
Ndrg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005256Protein NDRG1; Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53- [...]
4930550C14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000005262Uncharacterized protein C11orf65 homolog.
Klf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005279Krueppel-like factor 5; Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes.
Shbg protein networkhttps://string-db.org/network/10090.ENSMUSP00000005334Sex hormone-binding globulin; Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-d [...]
Senp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005336Sentrin-specific protease 3; Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which [...]
Corin protein networkhttps://string-db.org/network/10090.ENSMUSP00000005352Atrial natriuretic peptide-converting enzyme, activated protease fragment; Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic [...]
G6pc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005364Glucose-6-phosphatase 2; May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis (By simila [...]
App protein networkhttps://string-db.org/network/10090.ENSMUSP00000005406Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axono [...]
Zfp112 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005413Zinc finger protein 112; May be involved in transcriptional regulation.
Letm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005431Mitochondrial proton/calcium exchanger protein; Mitochondrial proton/calcium antiporter that mediates proton- dependent calcium efflux from mitochondrion. Crucial for the maintenance of mitochond [...]
Fgfr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005452Fibroblast growth factor receptor 4; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentia [...]
Casp14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005488Caspase-14 subunit p20, intermediate form; Non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and is required for cornifica [...]
Slc1a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005490Excitatory amino acid transporter 4; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter [...]
Slc1a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005493Excitatory amino acid transporter 1; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter [...]
Msh6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005503DNA mismatch repair protein Msh6; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiatin [...]
Fbxo11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005504F-box only protein 11; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradat [...]
Mlxipl protein networkhttps://string-db.org/network/10090.ENSMUSP00000005507Carbohydrate-responsive element-binding protein; Transcriptional repressor. Binds to the canonical and non- canonical E box sequences 5'-CACGTG-3'.
Stx1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000005509Syntaxin-1A; Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, [...]
Nid1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005532Nidogen-1; Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular [...]
Hmox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005548Heme oxygenase 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiologic [...]
Pafah1b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005583Platelet-activating factor acetylhydrolase IB subunit gamma; Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the dev [...]
Siglecg protein networkhttps://string-db.org/network/10090.ENSMUSP00000005592Sialic acid-binding Ig-like lectin 10; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sia [...]
Rfx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005600MHC class II regulatory factor RFX1; Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes (By similarity).
Il27ra protein networkhttps://string-db.org/network/10090.ENSMUSP00000005601Interleukin-27 receptor subunit alpha; Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in [...]
Prkaca protein networkhttps://string-db.org/network/10090.ENSMUSP00000005606cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regu [...]
Asf1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000005607Histone chaperone ASF1B; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly fact [...]
Myl10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005611Myosin regulatory light chain 10.
Dnajb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005620DnaJ homolog subfamily B member 1; Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 trans [...]
Msh4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005630MutS protein homolog 4; Involved in meiotic recombination. Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis.
Ndufs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005647NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the [...]
Por protein networkhttps://string-db.org/network/10090.ENSMUSP00000005651NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome [...]
Cyp2b13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005669Cytochrome P450, family 2, subfamily b, polypeptide 13; Belongs to the cytochrome P450 family.
Igf1r protein networkhttps://string-db.org/network/10090.ENSMUSP00000005671Insulin-like growth factor 1 receptor alpha chain; Receptor tyrosine kinase which mediates actions of insulin- like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS [...]
Fcer2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000005678Low affinity immunoglobulin epsilon Fc receptor; Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation [...]
Cyp2a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005685Cytochrome P450 2A5; Exhibits a high coumarin 7-hydroxylase activity.
Atp4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000005692Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the sto [...]
Trim28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005705Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome [...]
Chmp2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000005711Charged multivesicular body protein 2a; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation [...]
Ube2m protein networkhttps://string-db.org/network/10090.ENSMUSP00000005714NEDD8-conjugating enzyme Ubc12; Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E [...]
Ctr9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005749RNA polymerase-associated protein CTR9 homolog; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of dev [...]
Cabp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005791Calcium-binding protein 5; Inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials. Involved in the t [...]
Snx6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005798Sorting nexin-6, N-terminally processed; Involved in several stages of intracellular trafficking. Interacts with membranes phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 4,5-bi [...]
Mthfd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005810Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Although its dehydrogenase activity is NAD-specific, it can also utilize NADP at a reduced efficiency.
Kit protein networkhttps://string-db.org/network/10090.ENSMUSP00000005815Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and [...]
Tomm40l protein networkhttps://string-db.org/network/10090.ENSMUSP00000005817Mitochondrial import receptor subunit TOM40B; Potential channel-forming protein implicated in import of protein precursors into mitochondria.
Nr1i3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005820Nuclear receptor subfamily 1 group I member 3; Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase [...]
Pan2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005825PAN2-PAN3 deadenylation complex catalytic subunit Pan2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miR [...]
Cs protein networkhttps://string-db.org/network/10090.ENSMUSP00000005826Citrate synthase, mitochondrial; Belongs to the citrate synthase family.
Ampd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005829AMP deaminase 3; AMP deaminase plays a critical role in energy metabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Bcas2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005830Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and i [...]
Ctcf protein networkhttps://string-db.org/network/10090.ENSMUSP00000005841Transcriptional repressor CTCF; Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing intera [...]
Pvalb protein networkhttps://string-db.org/network/10090.ENSMUSP00000005860Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions; Belongs to the parvalbumin family.
Tfap4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005862Transcription factor AP4.
Vav1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005889Proto-oncogene vav; Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Klk9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005891Kallikrein-related-peptidase 9; Belongs to the peptidase S1 family.
Psmb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005923Proteasome subunit beta type-4; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles wi [...]
Klk1b16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005933Kallikrein 1-related peptidase b16.
Mmp12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005950Macrophage metalloelastase; May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for [...]
Slc30a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005952Zinc transporter 4; Probably involved in zinc transport out of the cytoplasm, may be by sequestration into an intracellular compartment.
Bloc1s6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005954Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as plat [...]
Adh5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005964Alcohol dehydrogenase class-3; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such [...]
Tnfsf14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000005976Tumor necrosis factor ligand superfamily member 14, membrane form; Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB and stimulates [...]
Pth1r protein networkhttps://string-db.org/network/10090.ENSMUSP00000006005Parathyroid hormone/parathyroid hormone-related peptide receptor; Receptor for parathyroid hormone and for parathyroid hormone- related peptide. The activity of this receptor is mediated by G pro [...]
Cnga2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006020Cyclic nucleotide-gated olfactory channel; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to b [...]
Reep5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006027Receptor expression-enhancing protein 5; May promote functional cell surface expression of olfactory receptors; Belongs to the DP1 family.
Ergic3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006035Endoplasmic reticulum-Golgi intermediate compartment protein 3; Possible role in transport between endoplasmic reticulum and Golgi.
Ncoa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006037Nuclear receptor coactivator 2; Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal doma [...]
Trh protein networkhttps://string-db.org/network/10090.ENSMUSP00000006046Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nerv [...]
Smpd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006053Sphingomyelin phosphodiesterase 4; Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. May sensitize cells to DNA damage- induced apoptosis.
Otx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006071Homeobox protein OTX1; Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC- 3'; Belongs to the paired homeobox fami [...]
Cyp2d26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006094Cytochrome P450 2D26; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a va [...]
Itgae protein networkhttps://string-db.org/network/10090.ENSMUSP00000006101Integrin alpha-E heavy chain; Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mu [...]
P2rx5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006104P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
Shpk protein networkhttps://string-db.org/network/10090.ENSMUSP00000006105Sedoheptulokinase; Acts as a modulator of macrophage activation through control of glucose metabolism.
Ephb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006112Ephrin type-B receptor 3; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling [...]
Tuft1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006123Tuftelin; Involved in the mineralization and structural organization of enamel; Belongs to the tuftelin family.
Rcn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006128Reticulocalbin-1; May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment; Belongs to the CREC family.
Dnase1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006136Deoxyribonuclease-1; Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs. Expressed by non-hematopoietic tissues and preferentially cleaves protein-fre [...]
Trap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006137Heat shock protein 75 kDa, mitochondrial; Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial compl [...]
Tyrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000061515,6-dihydroxyindole-2-carboxylic acid oxidase; Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic [...]
Kptn protein networkhttps://string-db.org/network/10090.ENSMUSP00000006178KICSTOR complex protein kaptin; As part of the KICSTOR complex functions in the amino acid- sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR [...]
Napa protein networkhttps://string-db.org/network/10090.ENSMUSP00000006181Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane [...]
Snf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006217Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal [...]
Vps54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006221Vacuolar protein sorting-associated protein 54; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The [...]
Ctsb protein networkhttps://string-db.org/network/10090.ENSMUSP00000006235Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein ME [...]
Tbcb protein networkhttps://string-db.org/network/10090.ENSMUSP00000006254Tubulin-folding cofactor B; Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded [...]
Inpp5k protein networkhttps://string-db.org/network/10090.ENSMUSP00000006286Inositol polyphosphate 5-phosphatase K; Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphati [...]
Crkl protein networkhttps://string-db.org/network/10090.ENSMUSP00000006293Crk-like protein; May mediate the transduction of intracellular signals.
Lrwd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006301Leucine-rich repeat and WD repeat-containing protein 1; Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replic [...]
Upk3bl protein networkhttps://string-db.org/network/10090.ENSMUSP00000006303Uroplakin-3b-like protein 1.
Tead4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006311Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting pr [...]
Prss16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006341Thymus-specific serine protease; Protease that may play a role in T-cell development; Belongs to the peptidase S28 family.
Cdkal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006353Threonylcarbamoyladenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladen [...]
Rhox6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006362Reproductive homeobox on X chromosome 6.
Htra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006367Serine protease HTRA1; Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells [...]
Zbtb17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006377Zinc finger and BTB domain-containing protein 17; Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of ce [...]
Clcnkb protein networkhttps://string-db.org/network/10090.ENSMUSP00000006378Chloride channel protein ClC-Kb; Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transdu [...]
Fam131c protein networkhttps://string-db.org/network/10090.ENSMUSP00000006380Family with sequence similarity 131, member C.
Fblim1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006381Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. [...]
Serpinb9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000006392Serine (or cysteine) peptidase inhibitor, clade B, member 9b; Belongs to the serpin family.
Epor protein networkhttps://string-db.org/network/10090.ENSMUSP00000006397Erythropoietin receptor; Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT [...]
Mob1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000006424MOB kinase activator 1B; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apop [...]
Atp6v1b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006431Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.
Atp6v1b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006435V-type proton ATPase subunit B, brain isoform; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartment [...]
Tep1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006444Telomerase protein component 1; Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini (By similarity). Also component of the ribonucleo [...]
Ttc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006451Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interac [...]
Upk1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000006476Uroplakin-1a; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal blad [...]
Tmem147 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006478Transmembrane protein 147; Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (By similarity). Negatively regulates CHRM3-mediate [...]
Ggt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006508Glutathione hydrolase 1 heavy chain; Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism o [...]
Gcat protein networkhttps://string-db.org/network/10090.ENSMUSP000000065442-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Mpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000006556Thrombopoietin receptor; Receptor for thrombopoietin that acts as a primary regulator of megakaryopoiesis and platelet production. May represent a regulatory molecule specific for TPO-R-dependent [...]
Elovl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006557Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endopla [...]
Tpbg protein networkhttps://string-db.org/network/10090.ENSMUSP00000006559Trophoblast glycoprotein; May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
Cdc20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006565Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is r [...]
Nectin4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006578Nectin-4; Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1.
Tmem189 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006587Plasmanylethanolamine desaturase; Plasmanylethanolamine desaturase involved in plasmalogen biogenesis in the endoplasmic reticulum membrane. Plasmalogens are glycerophospholipids with a hydrocarb [...]
Srm protein networkhttps://string-db.org/network/10090.ENSMUSP00000006611Spermidine synthase; Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low [...]
Epha2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006614Ephrin type-A receptor 2; Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signali [...]
Arhgef19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006618Rho guanine nucleotide exchange factor 19; Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase.
Rbm14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006625RNA-binding protein 14; May function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1 (By similarity). Regulates centriole biogenesis [...]
Actn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006626Alpha-actinin-3; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity); Belongs to the alpha-actinin [...]
Sptbn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006629Spectrin beta chain, non-erythrocytic 1; Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent m [...]
Zdhhc24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006632Probable palmitoyltransferase ZDHHC24.
Slc34a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006638Sodium-dependent phosphate transport protein 2C; May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 20-30% o [...]
Prl7a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006660Prolactin-7A2.
Prl8a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006662Prolactin-8A9.
Prl8a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006664Prolactin family 8, subfamily a, member 1.
Pdk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006669[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation [...]
Prtn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006679Myeloblastin; Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro). By cleaving and activating receptor F2RL1/PAR-2, enhances end [...]
Orm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006687Alpha-1-acid glycoprotein 3; Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain (By similarity). Appears to function in modulating [...]
Mvd protein networkhttps://string-db.org/network/10090.ENSMUSP00000006692Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes; Belongs to the diphosphomevalonate decarboxylase family.
Itih3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006697Inter-alpha-trypsin inhibitor heavy chain H3; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in [...]
Stimate protein networkhttps://string-db.org/network/10090.ENSMUSP00000006701Store-operated calcium entry regulator STIMATE; Acts as a regulator of store-operated Ca(2+) entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM), [...]
Itih1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006704Inter-alpha-trypsin inhibitor heavy chain H1; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in [...]
Wnt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006716Protein Wnt-6; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete re [...]
Wnt10a protein networkhttps://string-db.org/network/10090.ENSMUSP00000006718Protein Wnt-10a; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a role in normal ectod [...]
Cryba2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006721Beta-crystallin A2; Crystallins are the dominant structural components of the vertebrate eye lens.
Atp7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000006742Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.
Defb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006745Beta-defensin 2; Has bactericidal activity; Belongs to the beta-defensin family.
Slc4a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006749Band 3 anion transport protein; Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprot [...]
Rundc3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000006750RUN domain-containing protein 3A; May act as an effector of RAP2A in neuronal cells. Belongs to the RUNDC3 family.
Cdt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006760DNA replication factor Cdt1; Required for both DNA replication and mitosis. DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin re [...]
Snai3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006762Zinc finger protein SNAI3; Seems to inhibit myoblast differentiation. Transcriptional repressor of E-box-dependent transactivation of downstream myogenic bHLHs genes. Binds preferentially to the [...]
Aprt protein networkhttps://string-db.org/network/10090.ENSMUSP00000006764Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
Slc17a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006785Sodium-dependent phosphate transport protein 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the [...]
Slc17a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006786Sodium-dependent phosphate transport protein 3; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the [...]
Ncr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006792Natural cytotoxicity triggering receptor 1; Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Tcf23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006818Transcription factor 23; Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodim [...]
Nphs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006825Nephrin; Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the [...]
Aplp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006828Amyloid-like protein 1; May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding. Couple [...]
Qars protein networkhttps://string-db.org/network/10090.ENSMUSP00000006838Glutamine--tRNA ligase; Glutamine--tRNA ligase. Plays a critical role in brain development; Belongs to the class-I aminoacyl-tRNA synthetase family.
Qrich1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006851Glutamine-rich protein 1.
P4htm protein networkhttps://string-db.org/network/10090.ENSMUSP00000006853Transmembrane prolyl 4-hydroxylase; Catalyzes the post-translational formation of 4- hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564' [...]
Usp19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006854Ubiquitin carboxyl-terminal hydrolase 19; Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn [...]
Pola1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006856DNA polymerase alpha catalytic subunit; Catalytic subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiat [...]
D130043K22Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000006893Dyslexia-associated protein KIAA0319 homolog; Involved in neuronal migration during development of the cerebral neocortex. May function in a cell autonomous and a non-cell autonomous manner and p [...]
Gmnn protein networkhttps://string-db.org/network/10090.ENSMUSP00000006898Geminin; Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction [...]
Acot13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006900Acyl-coenzyme A thioesterase 13; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to [...]
Cdk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006911Cyclin-dependent kinase 4; Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the [...]
Pip4k2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000006912Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phos [...]
B4galnt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006914Beta-1,4 N-acetylgalactosaminyltransferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2; Belongs to the glycosyltransferase 2 family.
Mettl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006915tRNA (guanine-N(7)-)-methyltransferase; Methyltransferase that mediates the formation of N(7)- methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs). Catalyzes the [...]
Tph2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006949Tryptophan 5-hydroxylase 2; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Saa4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006952Serum amyloid A-4 protein; Major acute phase reactant. Apolipoprotein of the HDL complex.
Saa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006956Serum amyloid A-3 protein; Major acute phase reactant. Apolipoprotein of the HDL complex; Belongs to the SAA family.
Krt28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006963Keratin, type I cytoskeletal 28; Essential for the proper assembly of types I and II keratin protein complexes and the formation of keratin intermediate filaments in the inner root sheath (irs).
Krt23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006969Keratin, type I cytoskeletal 23; Belongs to the intermediate filament family.
Hcn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000006991Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1; Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to [...]
Acat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007005Acetyl-CoA acetyltransferase, cytosolic; Involved in the biosynthetic pathway of cholesterol.
Sod2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007012Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese [...]
Ik protein networkhttps://string-db.org/network/10090.ENSMUSP00000007042Protein Red; Involved in pre-mRNA splicing as a component of the spliceosome. Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA [...]
Tmco6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007046Transmembrane and coiled-coil domain-containing protein 6.
Ctnnb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007130Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on [...]
Eif1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000007139Eukaryotic translation initiation factor 1b; Probably involved in translation.
Klk1b11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007156Kallikrein 1-related peptidase b11; Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin; Belongs to the peptidase S1 family. Kallikrein subfamily.
Klk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007161Kallikrein-4; Has a major role in enamel formation. Required during the maturation stage of tooth development for clearance of enamel proteins and normal structural patterning of the crystalline [...]
Chrd protein networkhttps://string-db.org/network/10090.ENSMUSP00000007171Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequest [...]
Clcn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007207Chloride channel protein 2; Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction [...]
Psmd2 protein networkhttps://string-db.org/network/10090.ENSMUSP0000000721226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a k [...]
Ap2m1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007216AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. [...]
Syngr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007236Synaptogyrin-3; May play a role in regulated exocytosis. May indirectly regulate the activity of the plasma membrane dopamine transporter SLC6A3 and thereby regulate dopamine transport back from [...]
Vwa7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007245Von Willebrand factor A domain-containing protein 7.
Hspa1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000007248Heat shock 70 kDa protein 1-like; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesi [...]
Slc44a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007249Choline transporter-like protein 4; Choline transporter that plays a role in the choline- acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundl [...]
Msh5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007250MutS protein homolog 5; Involved in DNA mismatch repair and meiotic recombination processes. Facilitates crossovers between homologs during meiosis (By similarity); Belongs to the DNA mismatch re [...]
Abhd16a protein networkhttps://string-db.org/network/10090.ENSMUSP00000007251Phosphatidylserine lipase ABHD16A; Phosphatidylserine (PS) lipase that mediates the hydrolysis of phosphatidylserine to generate lysophosphatidylserine (LPS). LPS constitutes a class of signaling [...]
Neu1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007253Sialidase-1; Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme [...]
Ddah2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007255N(G),N(G)-dimethylarginine dimethylaminohydrolase 2; Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)- monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in [...]
Clic1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007257Chloride intracellular channel protein 1; Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occu [...]
Ly6g6d protein networkhttps://string-db.org/network/10090.ENSMUSP00000007259Lymphocyte antigen 6 complex locus protein G6d.
Lsm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007266U6 snRNA-associated Sm-like protein LSm2; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatal [...]
Krt14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007272Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5- KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in r [...]
Krt13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007275Keratin, type I cytoskeletal 13.
Krt16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007280Keratin, type I cytoskeletal 16; Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some infl [...]
Pole protein networkhttps://string-db.org/network/10090.ENSMUSP00000007296DNA polymerase epsilon catalytic subunit A; Catalytic component of the DNA polymerase epsilon complex (By similarity). Participates in chromosomal DNA replication. Required during synthesis of th [...]
Krt19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007317Keratin, type I cytoskeletal 19; Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle (By simi [...]
Krt31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007318Keratin, type I cuticular Ha1.
Atp12a protein networkhttps://string-db.org/network/10090.ENSMUSP00000007340Potassium-transporting ATPase alpha chain 2; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in va [...]
Kiss1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007433Metastasis-suppressor KiSS-1; Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidat [...]
Strada protein networkhttps://string-db.org/network/10090.ENSMUSP00000007444STE20-related kinase adapter protein alpha; Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation ty [...]
Akr1b7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007449Aldo-keto reductase family 1 member B7; Reduces a broad range of aliphatic and aromatic aldehydes to the corresponding alcohols. Reduces prostaglandins. May play a role in the metabolism of xenob [...]
Mrpl49 protein networkhttps://string-db.org/network/10090.ENSMUSP0000000748239S ribosomal protein L49, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL49 family.
Gatad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007559GATA zinc finger domain-containing protein 1; Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form [...]
Pcdhac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007584Protocadherin alpha subfamily C, 1.
2310003L06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000007601RIKEN cDNA 2310003L06 gene.
Ppp2r1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000007708Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the ca [...]
Tinf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007733TERF1-interacting nuclear factor 2; Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double- [...]
Tssk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007735Testis-specific serine/threonine-protein kinase 4; [Isoform 1]: Serine/threonine kinase which is involved in male germ cell development and in mature sperm function. May be involved in the Cre/Cr [...]
Hapln4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007738Hyaluronan and proteoglycan link protein 4; Binds to hyaluronic acid and may be involved in formation of the extracellular matrix; Belongs to the HAPLN family.
Dus3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000007747tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
Gtpbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007754tRNA modification GTPase GTPBP3, mitochondrial; GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs; Belongs to the TR [...]
Tgfbr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007757TGF-beta receptor type-1; Transmembrane serine/threonine kinase forming with the TGF- beta type II serine/threonine kinase receptor, TGFBR2, the non- promiscuous receptor for the TGF-beta cytokin [...]
Rad51c protein networkhttps://string-db.org/network/10090.ENSMUSP00000007790DNA repair protein RAD51 homolog 3; Essential for the homologous recombination (HR) pathway of DNA repair. Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA bre [...]
Gabrb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007797Gamma-aminobutyric acid receptor subunit beta-2; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. [...]
Cav1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007799Caveolin-1; May act as a scaffolding protein within caveolar membranes (By similarity). Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation [...]
Khsrp protein networkhttps://string-db.org/network/10090.ENSMUSP00000007814Far upstream element-binding protein 2; Binds to the dendritic targeting element and may play a role in mRNA trafficking. Part of a ternary complex that binds to the downstream control sequence ( [...]
Ccdc124 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007865Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages.
Rhoa protein networkhttps://string-db.org/network/10090.ENSMUSP00000007959Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a vari [...]
Hnrnpa0 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007980Heterogeneous nuclear ribonucleoprotein A0; mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post- transcriptional regulation of c [...]
Rbm28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000007993RNA-binding protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes.
Ddx49 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008004Probable ATP-dependent RNA helicase DDX49.
Id3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008016DNA-binding protein inhibitor ID-3; Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming he [...]
Tcap protein networkhttps://string-db.org/network/10090.ENSMUSP00000008021Telethonin; Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk (By similarity).
Crlf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008032Cytokine receptor-like factor 1; In complex with CLCF1, forms a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development (By similarity). Plays a role in the initi [...]
Rplp1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000000803660S acidic ribosomal protein P1; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family.
Cabs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008051Calcium-binding and spermatid-specific protein 1.
Hmgcll1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000080523-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic; Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3- methylglutaryl-CoA i [...]
Ttc9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000008088Tetratricopeptide repeat protein 9B; Belongs to the TTC9 family.
Phox2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000008090Paired mesoderm homeobox protein 2A; May be involved in regulating the specificity of expression of the catecholamine biosynthetic genes. Acts as a transcription activator/factor. Could maintain [...]
Abhd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008094Protein ABHD8; Belongs to the AB hydrolase superfamily.
Fhl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008280Four and a half LIM domains protein 2; May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor [...]
Clstn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008297Calsyntenin-3; May modulate calcium-mediated postsynaptic signals. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, [...]
Cers4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008350Ceramide synthase 4; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl [...]
Phax protein networkhttps://string-db.org/network/10090.ENSMUSP00000008445Phosphorylated adapter RNA export protein; A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding c [...]
1700109H08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000008451RIKEN cDNA 1700109H08 gene.
Relt protein networkhttps://string-db.org/network/10090.ENSMUSP00000008462Tumor necrosis factor receptor superfamily member 19L; May play a role in apoptosis. Induces activation of MAPK14/p38 and MAPK8/JNK MAPK cascades, when overexpressed. Involved in dental enamel fo [...]
Snrpb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008477U2 small nuclear ribonucleoprotein B'; Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA.
Prpf31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008517U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks [...]
Sertad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008528SERTA domain-containing protein 1; Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 [...]
Carhsp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008537Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA.
Elk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008542ETS domain-containing protein Elk-3; May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum res [...]
Herpud2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008573Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway.
Rdh13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008579Retinol dehydrogenase 13; Retinol dehydrogenase with a clear preference for NADP. Oxidizes all-trans-retinol, but seems to reduce all-trans-retinal with much higher efficiency. Has no activity to [...]
Adam21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008582Disintegrin and metalloproteinase domain-containing protein 21; May be involved in sperm maturation and/or fertilization. May also be involved in epithelia functions associated with establishing [...]
Nutf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008594Nuclear transport factor 2; Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transp [...]
Fut1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008605Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the s [...]
Rnf151 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008626RING finger protein 151; May be involved in acrosome formation of spermatids.
Dnajb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008733DnaJ homolog subfamily B member 6; Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. S [...]
Htr3b protein networkhttps://string-db.org/network/10090.ENSMUSP000000087345-hydroxytryptamine receptor 3B; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mit [...]
Rab25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008745Ras-related protein Rab-25; Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of [...]
Ubqln4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008748Ubiquilin-4; Regulator of protein degradation that mediates the proteasomal targeting of misfolded, mislocalized or accumulated proteins (By similarity). Acts by binding polyubiquitin chains of t [...]
Rps18 protein networkhttps://string-db.org/network/10090.ENSMUSP0000000881240S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.
Zfp955a protein networkhttps://string-db.org/network/10090.ENSMUSP00000008830Zinc finger protein 422, related sequence 1.
Coro1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000008893Coronin-1B; Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity).
Man1a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008907Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce [...]
Tppp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008957Tubulin polymerization-promoting protein family member 2; Probable regulator of microtubule dynamics required for sperm motility (Probable). In contrast to other members of the family, has no mic [...]
Cldn13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008987Claudin-13; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
Sptbn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008991Spectrin beta chain; Belongs to the spectrin family.
Hdac5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000008999Histone deacetylase 5; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic rep [...]
Rala protein networkhttps://string-db.org/network/10090.ENSMUSP00000009003Ras-related protein Ral-A; Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane [...]
Clec3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000009018C-type lectin domain family 3 member A; Promotes cell adhesion to laminin and fibronectin.
Vdac3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009036Voltage-dependent anion-selective channel protein 3; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
Abcb1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000009058ATP-dependent translocase ABCB1; Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membran [...]
Vps72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009102Vacuolar protein sorting-associated protein 72 homolog; Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component [...]
Gabpa protein networkhttps://string-db.org/network/10090.ENSMUSP00000009120GA-binding protein alpha chain; Transcription factor capable of interacting with purine rich repeats (GA repeats); Belongs to the ETS family.
Bmp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009143Bone morphogenetic protein 7; Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation [...]
Dynll1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009157Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to [...]
Cabp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009219Calcium-binding protein 7; Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.
Zmat5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009220Zinc finger matrin-type protein 5.
Ap1b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009234AP-1 complex subunit beta-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP com [...]
Derl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009236Derlin-3; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel [...]
Bcl2l13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009256Bcl-2-like protein 13; May promote the activation of caspase-3 and apoptosis.
Spatc1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000009259Speriolin-like protein; Belongs to the speriolin family.
Dgcr8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009321Microprocessor complex subunit DGCR8; Component of the microprocessor complex that acts as a RNA- and heme-binding protein that is involved in the initial step of microRNA (miRNA) biogenesis. Com [...]
Ccl8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009329C-C motif chemokine 8; Chemotactic factor that attracts monocytes. This protein can bind heparin (By similarity).
Ifi211 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009340Interferon-activable protein 205-B; May act as a transcriptional regulator in the myeloid lineage. Inhibits cell growth via p53/TP53 and RB1-dependent and independent pathways; Belongs to the HIN [...]
Mymk protein networkhttps://string-db.org/network/10090.ENSMUSP00000009358Protein myomaker; Myoblast-specific protein that mediates myoblast fusion, an essential step for the formation of multi-nucleated muscle fibers. Actively participates in the membrane fusion react [...]
Trpm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009390Transient receptor potential cation channel subfamily M member 5; Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays [...]
Ascl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009392Achaete-scute homolog 2; AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
Tspan32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009396Tetraspanin-32; Belongs to the tetraspanin (TM4SF) family.
Zfp212 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009411Zinc finger protein 212.
Rarres2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009425Retinoic acid receptor responder protein 2; Adipocyte-secreted protein (adipokine) that regulates adipogenesis, metabolism and inflammation through activation of the chemokine-like receptor 1 (CM [...]
Pttg1ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000009435Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation.
Slc16a12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009522Monocarboxylate transporter 12; Proton-linked monocarboxylate transporter that mediates creatine transport across the plasma membrane.
Syn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009538Synapsin-2; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradren [...]
Elk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009550ETS domain-containing protein Elk-1; Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) [...]
Kcnc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009617Potassium voltage-gated channel subfamily C member 4; This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in res [...]
Ush1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000009667Harmonin; Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for nor [...]
Rnmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000009679mRNA cap guanine-N7 methyltransferase; Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of [...]
Kcnq1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009689Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Assoc [...]
Srp14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009693Signal recognition particle 14 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with [...]
Cdk9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009699Cyclin-dependent kinase 9; Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elong [...]
Eng protein networkhttps://string-db.org/network/10090.ENSMUSP00000009705Endoglin; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature (By similarity). Regul [...]
Tor2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000009707Torsin-2A; Belongs to the ClpA/ClpB family. Torsin subfamily.
Mrtfb protein networkhttps://string-db.org/network/10090.ENSMUSP00000009713Myocardin-related transcription factor B; Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.
Syngr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009727Synaptogyrin-1; May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesic [...]
St6galnac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009732Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; Transfers CMP-NeuAc with an alpha-2,6-linkage to the GalNAc residues of GalNAc-O-Ser/Thr, Gal-beta-1,3-GalNAc-O-Ser/Thr and NeuAc- alp [...]
Taf7l protein networkhttps://string-db.org/network/10090.ENSMUSP00000009740Transcription initiation factor TFIID subunit 7-like; Probably functions as a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protei [...]
Tex15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009772Testis-expressed protein 15; Required during spermatogenesis for normal chromosome synapsis and meiotic recombination in germ cells. Necessary for formation of DMC1 and RAD51 foci on meiotic chro [...]
Ppp2cb protein networkhttps://string-db.org/network/10090.ENSMUSP00000009774Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
G0s2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009777G0/G1 switch protein 2; Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers.
P4ha1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009789Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Pla2g12b protein networkhttps://string-db.org/network/10090.ENSMUSP00000009790Group XIIB secretory phospholipase A2-like protein; Not known; does not seem to have catalytic activity.
Oit3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009798Oncoprotein-induced transcript 3 protein; May be involved in hepatocellular function and development.
Tex11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009814Testis-expressed protein 11; Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers; Belongs to the SPO22 family.
Fxyd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009831FXYD domain-containing ion transport regulator 5; Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (By similarity).
Kcnd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000009875Potassium voltage-gated channel subfamily D member 1; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in the heart an [...]
Sdhb protein networkhttps://string-db.org/network/10090.ENSMUSP00000010007Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial elec [...]
Snap47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010038Synaptosomal-associated protein 47; May play a role in intracellular membrane fusion. Belongs to the SVAP1 family.
Wnt3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000010044Protein Wnt-3a; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription [...]
Kdsr protein networkhttps://string-db.org/network/10090.ENSMUSP000000100493-ketodihydrosphingosine reductase; Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Nxf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010085Nuclear RNA export factor 2.
Tktl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010127Transketolase-like protein 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate; B [...]
Zmynd10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010188Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respect [...]
Tmem115 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010189Transmembrane protein 115; May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi.
Ifrd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010192Interferon-related developmental regulator 2.
Hyal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010195Hyaluronidase-1; May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth.
Tusc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010198Tumor suppressor candidate 2.
Nprl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010201GATOR complex protein NPRL2; As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrol [...]
Gnat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010205Guanine nucleotide-binding protein G(t) subunit alpha-1; Functions as signal transducer for the rod photoreceptor RHO. Required for normal RHO-mediated light perception by the retina (By similari [...]
Nxf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010241Nuclear RNA export factor 1; Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (T [...]
Tmem223 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010248Transmembrane protein 223.
Tmem179b protein networkhttps://string-db.org/network/10090.ENSMUSP00000010249Transmembrane protein 179B.
Slc22a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010250Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic an [...]
Slc22a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010251Solute carrier family 22 member 8; Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Mediates the uptake of [...]
Slc47a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010267Multidrug and toxin extrusion protein 1; Solute transporter for tetraethylammonium (TEA), 1-methyl-4- phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanid [...]
Wdr77 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010278Methylosome protein 50; Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77 and CLNS1A, which modifies specific arginines to dimethylarginines in several spliceosomal Sm [...]
Tmigd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010279Transmembrane domain-containing protein TMIGD3.
Pifo protein networkhttps://string-db.org/network/10090.ENSMUSP00000010280Protein pitchfork; During primary cilia disassembly, involved in cilia disassembly. Required specifically to control cilia retraction as well as the liberation and duplication of the basal body/c [...]
Tnfrsf13b protein networkhttps://string-db.org/network/10090.ENSMUSP00000010286Tumor necrosis factor receptor superfamily member 13B; Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin- dependent [...]
Spire2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010298Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibe [...]
Fdx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010348Ferredoxin-2, mitochondrial; Essential for heme A and Fe/S protein biosynthesis. Belongs to the adrenodoxin/putidaredoxin family.
2610507B11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000010421Protein KIAA0100; May be involved in membrane trafficking. Belongs to the SABRE family.
AI597479 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010434Ashwin.
Tmem86a protein networkhttps://string-db.org/network/10090.ENSMUSP00000010451Lysoplasmalogenase-like protein TMEM86A.
Ifi35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010502Interferon-induced 35 kDa protein homolog.
Rdm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010506RAD52 motif-containing protein 1; May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA (By similarity).
Nedd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010520NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 [...]
Gosr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010536Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or sol [...]
Mrpl52 protein networkhttps://string-db.org/network/10090.ENSMUSP0000001055039S ribosomal protein L52, mitochondrial.
Spaca7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010579Sperm acrosome-associated protein 7; Involved in fertilization. Seems not to play a direct role in sperm-egg binding or gamete fusion.
Il12rb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010605Interleukin-12 receptor subunit beta-2; Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as N [...]
Gm266 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010673Gene model 266, (NCBI).
Dazl protein networkhttps://string-db.org/network/10090.ENSMUSP00000010736Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRN [...]
Acaa1b protein networkhttps://string-db.org/network/10090.ENSMUSP000000107953-ketoacyl-CoA thiolase B, peroxisomal.
Plcd1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000108041-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by acti [...]
Fads1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010807Acyl-CoA (8-3)-desaturase; Acts as a front-end fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 5 located between a preexisting double bond and the carboxyl end [...]
Cars protein networkhttps://string-db.org/network/10090.ENSMUSP00000010899Cysteine--tRNA ligase, cytoplasmic.
Phlda2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010904Pleckstrin homology-like domain family A member 2; Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing [...]
Asz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010940Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which [...]
Wnt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010941Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Functions as upstream regulator of FGF10 [...]
Kdelr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010974ER lumen protein-retaining receptor 3; Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Gol [...]
Cfap97d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000010985Uncharacterized protein CFAP97D1; Belongs to the CFAP97 family.
Dnajc19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011029Mitochondrial import inner membrane translocase subunit TIM14; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inne [...]
Apip protein networkhttps://string-db.org/network/10090.ENSMUSP00000011055Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the me [...]
Pdhx protein networkhttps://string-db.org/network/10090.ENSMUSP00000011058Pyruvate dehydrogenase protein X component, mitochondrial; Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenas [...]
Mcoln2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011152Mucolipin-2; Nonselective cation channel probably playing a role in the regulation of membrane trafficking events. Acts as Ca(2+)-permeable cation channel with inwardly rectifying activity. May a [...]
Slc5a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011178Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is pro [...]
Panx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011262Pannexin-3; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
Cfap161 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011298Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly.
Brf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011302Transcription factor IIIB 90 kDa subunit; General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters.
Vipr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011315Vasoactive intestinal polypeptide receptor 2; This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can [...]
Prss45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011391Inactive serine protease 45; Belongs to the peptidase S1 family.
Thg1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000011398Probable tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidel [...]
Adam19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011400Disintegrin and metalloproteinase domain-containing protein 19; Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, [...]
Cd209d protein networkhttps://string-db.org/network/10090.ENSMUSP00000011445CD209 antigen-like protein D; Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calciu [...]
Sugp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011450SURP and G-patch domain-containing protein 1; Plays a role in pre-mRNA splicing.
Acad9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011492Complex I assembly factor ACAD9, mitochondrial; As part of the MCIA complex, primarily participates to the assembly of the mitochondrial complex I and therefore plays a role in oxidative phosphor [...]
Dmrtc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011493Doublesex- and mab-3-related transcription factor C2; May be involved in sexual development; Belongs to the DMRT family.
Dhdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000011526Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase.
Cpb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011607Carboxypeptidase B1 (Tissue).
Dennd1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000011623DENN domain-containing protein 1C; Guanine nucleotide exchange factor (GEF) which may activate RAB8A, RAB13 and RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab prote [...]
Fsd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011733Fibronectin type III and SPRY domain-containing protein 1; May be involved in microtubule organization and stabilization.
Pinlyp protein networkhttps://string-db.org/network/10090.ENSMUSP00000011776Phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein.
Sptbn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011895Spectrin beta chain; Belongs to the spectrin family.
Pgam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011896Phosphoglycerate mutase 1; Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but w [...]
Snapc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000011981snRNA-activating protein complex subunit 2; Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence elem [...]
Gltp protein networkhttps://string-db.org/network/10090.ENSMUSP00000012028Glycolipid transfer protein; Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transf [...]
Dgcr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000012152Integral membrane protein DGCR2/IDD; Probably plays a role in neural crest cell migration. May play a role in delivery of extracellular signals.
Scarf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000012161Scavenger receptor class F member 2; Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of a [...]
Med15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000012259Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Bmp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000012281Bone morphogenetic protein 5; Induces cartilage and bone formation; Belongs to the TGF-beta family.
Zfp729a protein networkhttps://string-db.org/network/10090.ENSMUSP00000012314Zinc finger protein 729a.
Gstm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000012348Glutathione S-transferase Mu 2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family.
Tex22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000012355Testis-expressed protein 22.
Wnt8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000012426Protein Wnt-8a; Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in embryonic patterning.
Nanog protein networkhttps://string-db.org/network/10090.ENSMUSP00000012540Homeobox protein NANOG; Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their diffe [...]
Hps3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000012580Hermansky-Pudlak syndrome 3 protein homolog; Involved in early stages of melanosome biogenesis and maturation.
Kif11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000012587Kinesin-like protein KIF11; Motor protein required for establishing a bipolar spindle during mitosis. Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to t [...]
Rpa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000012627Replication protein A 14 kDa subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replicat [...]
Phox2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000012664Paired mesoderm homeobox protein 2B; Belongs to the paired homeobox family.
Cd209a protein networkhttps://string-db.org/network/10090.ENSMUSP00000012847CD209 antigen-like protein A; Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calciu [...]
Zfp729b protein networkhttps://string-db.org/network/10090.ENSMUSP00000012873Zinc finger protein 729b.
Strn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013130Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein (By similarity); Belongs to the WD repeat striatin family.
Amotl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013220Angiomotin-like protein 1; Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.
2200002J24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000013227RIKEN cDNA 2200002J24 gene.
Tmem190 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013235Transmembrane protein 190.
Zkscan17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013262Zinc finger protein 496; DNA-binding transcription factor that can both act as an activator and a repressor; Belongs to the krueppel C2H2-type zinc-finger protein family.
Gfod2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013294Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly; Belongs to the Gfo/Idh/MocA family.
Enkd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013299Enkurin domain-containing protein 1.
4933405L10Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000013302Uncharacterized protein C16orf86 homolog.
Atp6v0d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013304V-type proton ATPase subunit d 1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryot [...]
Arih2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013338E3 ubiquitin-protein ligase ARIH2; E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3 (By similarity). Acts as an [...]
Adh4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013458All-trans-retinol dehydrogenase [NAD(+)] ADH4; Catalyzes the NAD-dependent oxidation of either all-trans- retinol or 9-cis-retinol (By similarity). Also oxidizes long chain omega-hydroxy fatty ac [...]
4931406B18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000013497RIKEN cDNA 4931406B18 gene.
Igf2bp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013559Insulin-like growth factor 2 mRNA-binding protein 1; RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows m [...]
Fgfrl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013633Fibroblast growth factor receptor-like 1; Has a negative effect on cell proliferation.
Bcas1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013667Breast carcinoma-amplified sequence 1 homolog; Required for myelination.
Commd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013693COMM domain-containing protein 8; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B.
Ndufs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013737NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the [...]
Fnbp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013759Formin-binding protein 4.
Atraid protein networkhttps://string-db.org/network/10090.ENSMUSP00000013766All-trans retinoic acid-induced differentiation factor; Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 e [...]
Trim54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013771Tripartite motif-containing protein 54; May bind and stabilize microtubules during myotubes formation.
Cad protein networkhttps://string-db.org/network/10090.ENSMUSP00000013773Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).
1810065E05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000013797RIKEN cDNA 1810065E05 gene.
Pten protein networkhttps://string-db.org/network/10090.ENSMUSP00000013807Phosphatase and tensin homolog; In motile cells, suppresses the formation of lateral pseudopods and thereby promotes cell polarization and directed movement (By similarity). Tumor suppressor. Act [...]
Pea15a protein networkhttps://string-db.org/network/10090.ENSMUSP00000013842Astrocytic phosphoprotein PEA-15; Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inh [...]
Timm23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013845Mitochondrial import inner membrane translocase subunit Tim23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across th [...]
Tnfaip8l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013851Tumor necrosis factor alpha-induced protein 8-like protein 2; Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like recep [...]
Ppp1r12c protein networkhttps://string-db.org/network/10090.ENSMUSP00000013886Protein phosphatase 1 regulatory subunit 12C; Regulates myosin phosphatase activity.
Ly6g6e protein networkhttps://string-db.org/network/10090.ENSMUSP00000013910Lymphocyte antigen 6G6e; Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro potentiates alpha-3:beta-4- containing nAChRs maximum response by increasi [...]
Ehmt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013931Histone-lysine N-methyltransferase EHMT2; Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me repre [...]
Birc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013949Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase sig [...]
Pip4k2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000013970Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum.
Abca4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000013995Retinal-specific phospholipid-transporting ATPase ABCA4; Catalyzes the translocation of specific phospholipids from the extracellular/lumenal to the cytoplasmic leaflet of membrane coupled to the [...]
Rnf170 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014022E3 ubiquitin-protein ligase RNF170; E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradatio [...]
Klk10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014058Kallikrein-related-peptidase 10; Belongs to the peptidase S1 family.
Clip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014065CAP-Gly domain-containing linker protein 3; Functions as a cytoplasmic linker protein. Involved in TGN- endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and [...]
Thap8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014072THAP domain-containing 8.
Mcemp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014118Mast cell-expressed membrane protein 1.
Pax5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014174Paired box protein Pax-5; May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specifi [...]
Tctex1d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014220Tctex1 domain-containing protein 2; Required for proper retrograde ciliary transport. Belongs to the dynein light chain Tctex-type family.
Chp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014221Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcriptio [...]
Sval2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014248Seminal vesicle antigen-like 2.
Apbb1ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000014290Amyloid beta A4 precursor protein-binding family B member 1-interacting protein; Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses in [...]
Tvp23b protein networkhttps://string-db.org/network/10090.ENSMUSP00000014321Golgi apparatus membrane protein TVP23 homolog B.
Dnajc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014339DnaJ homolog subfamily C member 7; Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progestero [...]
Cacybp protein networkhttps://string-db.org/network/10090.ENSMUSP00000014370Calcyclin-binding protein; May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 com [...]
Pigl protein networkhttps://string-db.org/network/10090.ENSMUSP00000014389N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol (By similarity); Belongs [...]
Ankrd17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014421Ankyrin repeat domain-containing protein 17; Could play pivotal roles in cell cycle and DNA regulation. Involved in innate immune defense against viruse by positively regulating the viral dsRNA r [...]
Ndufa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014438NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved [...]
Pam16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014445Mitochondrial import inner membrane translocase subunit TIM16; Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase a [...]
Glis2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014447Zinc finger protein GLIS2; Can act either as a transcriptional repressor or as a transcriptional activator, depending on the cell context. Acts as a repressor of the Hedgehog signaling pathway. R [...]
Klra8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014476Killer cell lectin-like receptor 8; Receptor on natural killer (NK) cells for class I MHC.
Anapc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014499Anaphase-promoting complex subunit 1; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G [...]
Mertk protein networkhttps://string-db.org/network/10090.ENSMUSP00000014505Tyrosine-protein kinase Mer; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. [...]
Ldhc protein networkhttps://string-db.org/network/10090.ENSMUSP00000014545L-lactate dehydrogenase C chain; Possible role in sperm motility; Belongs to the LDH/MDH superfamily. LDH family.
Tsg101 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014546Tumor susceptibility gene 101 protein; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of end [...]
Hps5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014562Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates [...]
Plg protein networkhttps://string-db.org/network/10090.ENSMUSP00000014578Plasmin heavy chain A, short form; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, [...]
Blk protein networkhttps://string-db.org/network/10090.ENSMUSP00000014597Tyrosine-protein kinase Blk; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of sever [...]
Rnf166 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014614E3 ubiquitin-protein ligase RNF166; E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates. In turn, participates in different biological processes including interfe [...]
Ankrd28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014640Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A; Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein su [...]
Ankrd52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014642Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C; Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein su [...]
Pkd2l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014647Polycystic kidney disease 2-like 2 protein; May function as a subunit of a cation channel and play a role in fertilization.
Tmbim7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014673Transmembrane BAX inhibitor motif-containing 7; Belongs to the BI1 family.
U2af1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014684Splicing factor U2AF 35 kDa subunit; Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required fo [...]
Clec4f protein networkhttps://string-db.org/network/10090.ENSMUSP00000014686C-type lectin domain family 4 member F; Receptor with an affinity for galactose and fucose. Could be involved in endocytosis.
Klra17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014687Killer cell lectin-like receptor, subfamily A, member 17.
Wdfy2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014691WD repeat and FYVE domain-containing protein 2; Acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-depende [...]
Rbsn protein networkhttps://string-db.org/network/10090.ENSMUSP00000014694Rabenosyn-5; Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathr [...]
Dguok protein networkhttps://string-db.org/network/10090.ENSMUSP00000014698Deoxyguanosine kinase, mitochondrial; Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where [...]
Csf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014743Processed macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especial [...]
Alx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014747Homeobox protein aristaless-like 3; Transcriptional regulator with a possible role in patterning of mesoderm during development; Belongs to the paired homeobox family.
Slc25a11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014750Mitochondrial 2-oxoglutarate/malate carrier protein; Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxyl [...]
Ceacam16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014830Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane; Belongs to the immunoglobulin superfa [...]
Hoxa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014848Homeobox protein Hox-A2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Ankrd53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014891Ankyrin repeat domain-containing protein 53; Required for normal progression through mitosis. Involved in chromosome alignment and cytokinesis via regulation of microtubules polymerization.
Tex261 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014892Protein TEX261.
Psmb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014913Proteasome subunit beta type-1; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles wi [...]
Dll1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014917Dll1-derived cell-associated form; Transmembrane ligand protein of NOTCH1, NOTCH2 and NOTCH3 receptors that binds the extracellular domain (ECD) of Notch receptor in a cis and trans fashion manne [...]
Nol3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014920Nucleolar protein 3; Apoptosis repressor that blocks multiple modes of cell death. Inhibits extrinsic apoptotic pathways through two different ways. Firstly by interacting with FAS and FADD upon [...]
Fhod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014922FH1/FH2 domain-containing protein 1; Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of m [...]
Plekhg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014927Pleckstrin homology domain-containing, family G (with RhoGef domain) member 4.
Stc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000014957Stanniocalcin-1; Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia; Belongs to the stanniocalcin family.
Tmem208 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015000Transmembrane protein 208; May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
E2f4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015003Transcription factor E2F4; Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of gen [...]
Surf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015011Surfeit locus protein 4; May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi. Belongs to the SURF4 family.
Surf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015017Surfeit locus protein 2; Belongs to the SURF2 family.
Dnajb9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015049DnaJ homolog subfamily B member 9; Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (By similarity). J domain-contai [...]
Ppp1cb protein networkhttps://string-db.org/network/10090.ENSMUSP00000015100Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hu [...]
Tsen15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015124tRNA-splicing endonuclease subunit Sen15; Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. I [...]
Limk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015137LIM domain kinase 1; Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pa [...]
Eln protein networkhttps://string-db.org/network/10090.ENSMUSP00000015138Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabili [...]
Efr3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000015146Protein EFR3 homolog A; Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphat [...]
Trappc2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000015157Trafficking protein particle complex subunit 2-like protein; May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Acsf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015160Malonate--CoA ligase ACSF3, mitochondrial; Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respec [...]
Galns protein networkhttps://string-db.org/network/10090.ENSMUSP00000015171N-acetylgalactosamine-6-sulfatase; Belongs to the sulfatase family.
Gata2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015197Endothelial transcription factor GATA-2; Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'- AGATAG-3'.
Ptgds protein networkhttps://string-db.org/network/10090.ENSMUSP00000015234Prostaglandin-H2 D-isomerase; Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved i [...]
Edf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015236Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activit [...]
Fbxw5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015239F-box/WD repeat-containing protein 5; Substrate recognition component of both SCF (SKP1-CUL1-F-box protein) and DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes. Substrate-specific ada [...]
Prss28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015267Serine protease 28; Involved in embryo hatching and implantation.
Lrrk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015277Leucine-rich repeat serine/threonine-protein kinase 1.
Aldh1a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015278Aldehyde dehydrogenase family 1 member A3; NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid. Has high activity with all-trans retinal, and has much lower in vitr [...]
Casd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015333N-acetylneuraminate 9-O-acetyltransferase; O-acetyltransferase that catalyzes 9-O-acetylation of sialic acids. Sialic acids are sugars at the reducing end of glycoproteins and glycolipids, and ar [...]
Cnksr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015346Connector enhancer of kinase suppressor of ras 3; Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport throug [...]
Mtmr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015358Myotubularin-related protein 1; Lipid phosphatase that has high specificity for phosphatidylinositol 3-phosphate and has no activity with phosphatidylinositol 4-phosphate, phosphatidylinositol (4 [...]
Nipsnap3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000015391Protein NipSnap homolog 3B.
Mmp13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015394Collagenase 3; Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type I [...]
Lage3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015433EKC/KEOPS complex subunit Lage3; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons [...]
Gdi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015435Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Prom [...]
Sash1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015449SAM and SH3 domain-containing protein 1; Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation. It acts as a scaffold molecule to assemble a molecular complex that include [...]
Gadd45b protein networkhttps://string-db.org/network/10090.ENSMUSP00000015456Growth arrest and DNA damage-inducible protein GADD45 beta; Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK (By similarity).
Slamf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015460Signaling lymphocytic activation molecule; Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interact [...]
Endog protein networkhttps://string-db.org/network/10090.ENSMUSP00000015481Endonuclease G, mitochondrial; Cleaves DNA at double-stranded (DG)n.(DC)n and at single- stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNas [...]
Cybb protein networkhttps://string-db.org/network/10090.ENSMUSP00000015484Cytochrome b-245 heavy chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single e [...]
Xk protein networkhttps://string-db.org/network/10090.ENSMUSP00000015486Membrane transport protein XK; May be involved in sodium-dependent transport of neutral amino acids or oligopeptides.
Pcolce2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015498Procollagen C-endopeptidase enhancer 2; Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.
Clpx protein networkhttps://string-db.org/network/10090.ENSMUSP00000015501ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial; ATP-dependent specificity component of the Clp protease complex. Hydrolyzes ATP. Targets specific substrates for degradati [...]
Mov10l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015509RNA helicase Mov10l1; [Isoform 1]: ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline inte [...]
Plxnd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015511Plexin-D1; Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wi [...]
Cd83 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015540CD83 antigen; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.
Mcpt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015576Mast cell protease 2.
Gzmg protein networkhttps://string-db.org/network/10090.ENSMUSP00000015578Granzyme G; This enzyme is probably necessary for target cell lysis in cell-mediated immune responses; Belongs to the peptidase S1 family. Granzyme subfamily.
Gzmb protein networkhttps://string-db.org/network/10090.ENSMUSP00000015581Granzyme B(G,H); This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specif [...]
Ctsg protein networkhttps://string-db.org/network/10090.ENSMUSP00000015583Cathepsin G; This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movement and mitosis.
Gzmc protein networkhttps://string-db.org/network/10090.ENSMUSP00000015585Granzyme C; This enzyme is probably necessary for target cell lysis in cell-mediated immune responses; Belongs to the peptidase S1 family. Granzyme subfamily.
Gzmn protein networkhttps://string-db.org/network/10090.ENSMUSP00000015587Granzyme N; Belongs to the peptidase S1 family.
Mcpt8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015594Mast cell protease 8.
Ager protein networkhttps://string-db.org/network/10090.ENSMUSP00000015596Advanced glycosylation end product-specific receptor; Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vasc [...]
Atf6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000015605Processed cyclic AMP-dependent transcription factor ATF-6 beta; Transcriptional factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER st [...]
Egfl8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015611Epidermal growth factor-like protein 8.
Notch4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015612Neurogenic locus notch homolog protein 4; Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the re [...]
Prrt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015620Proline-rich transmembrane protein 1.
Rnf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015622E3 ubiquitin-protein ligase RNF5; Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiqui [...]
Fam163a protein networkhttps://string-db.org/network/10090.ENSMUSP00000015628Protein FAM163A.
2310057J18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000015663Protein LEG1 homolog; May be involved in early liver development. Belongs to the LEG1 family.
Ctsk protein networkhttps://string-db.org/network/10090.ENSMUSP00000015664Cathepsin K; Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degra [...]
Ctss protein networkhttps://string-db.org/network/10090.ENSMUSP00000015667Cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specifi [...]
Lpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000015712Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an i [...]
Nkx2-5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015723Homeobox protein Nkx-2.5; Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. Binds to the core DNA [...]
Bnip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015725Vesicle transport protein SEC20; As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization. Pl [...]
Srf protein networkhttps://string-db.org/network/10090.ENSMUSP00000015749Serum response factor; SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initia [...]
Gata5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015771Transcription factor GATA-5; Transcription factor required during cardiovascular development (By similarity). Plays an important role in the transcriptional program(s) that underlies smooth muscl [...]
Lama5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015791Laminin subunit alpha-5; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development [...]
Steap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015796Metalloreductase STEAP1; Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Belongs to the STEAP family.
Hspa8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015800Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthes [...]
Pdzd11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015812PDZ domain-containing protein 11; Mediates docking of ADAM10 to zonula adherens by interacting with PLEKHA7 which is required for PLEKHA7 to interact with the ADAM10- binding protein TSPAN33.
Acadsb protein networkhttps://string-db.org/network/10090.ENSMUSP00000015829Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial; Has greatest activity toward short branched chain acyl-CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2- [...]
Setdb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015841Histone-lysine N-methyltransferase SETDB1; Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic tran [...]
Prune1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015855Exopolyphosphatase PRUNE1; Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, migration and differentiation, and acts as a n [...]
Cers2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015858Ceramide synthase 2; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very- long (C22:0-C24:0) chain as acyl donor.
Nlrp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015866NACHT, LRR and PYD domains-containing protein 5; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.
Capza2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015877F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of sub [...]
Plekho1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015889Pleckstrin homology domain-containing family O member 1; Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target [...]
Vps45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015891Vacuolar protein sorting-associated protein 45; May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network.
Prpf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015892U4/U6 small nuclear ribonucleoprotein Prp3; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precat [...]
Ppil4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015901Peptidyl-prolyl cis-trans isomerase-like 4; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Cnih1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015903Protein cornichon homolog 1; Involved in the selective transport and maturation of TGF- alpha family proteins.
Med22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015920Mediator of RNA polymerase II transcription subunit 22; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Surf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015934Surfeit locus protein 1; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly [...]
Bhmt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000015941S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl d [...]
Qdpr protein networkhttps://string-db.org/network/10090.ENSMUSP00000015950Dihydropteridine reductase; The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases; Belongs to the short-chain d [...]
Rxrg protein networkhttps://string-db.org/network/10090.ENSMUSP00000015987Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retin [...]
Cd5l protein networkhttps://string-db.org/network/10090.ENSMUSP00000015998CD5 antigen-like; Secreted protein that acts as a key regulator of lipid synthesis: mainly expressed by macrophages in lymphoid and inflamed tissues and regulates mechanisms in inflammatory respo [...]
Fam184b protein networkhttps://string-db.org/network/10090.ENSMUSP00000016023Protein FAM184B.
Lcorl protein networkhttps://string-db.org/network/10090.ENSMUSP00000016026Ligand-dependent nuclear receptor corepressor-like protein; May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'. May play a role in spermatog [...]
Lta4h protein networkhttps://string-db.org/network/10090.ENSMUSP00000016033Leukotriene A-4 hydrolase; Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.
Amdhd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016034Probable imidazolonepropionase.
Rrbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016072Ribosome-binding protein 1; Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane.
Macroh2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016081Core histone macro-H2A.1; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limitin [...]
Gtf2ird2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016086General transcription factor II-I repeat domain-containing protein 2.
Castor2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016088Cytosolic arginine sensor for mTORC1 subunit 2; Functions as a negative regulator of the TORC1 signaling pathway through the GATOR complex. As part of homodimers or heterodimers with CASTOR1, dir [...]
Ncf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016094Neutrophil cytosol factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
Adss protein networkhttps://string-db.org/network/10090.ENSMUSP00000016105Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosy [...]
Il17rb protein networkhttps://string-db.org/network/10090.ENSMUSP00000016110Interleukin-17 receptor B; Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.
Lrrc27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016124Leucine-rich repeat-containing protein 27.
Stk32c protein networkhttps://string-db.org/network/10090.ENSMUSP00000016125Serine/threonine-protein kinase 32C.
Fnta protein networkhttps://string-db.org/network/10090.ENSMUSP00000016138Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfe [...]
Wasf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016143Wiskott-Aldrich syndrome protein family member 3; Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. [...]
Plpp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016144Phospholipid phosphatase 1; Magnesium-independent phospholipid phosphatase of the plasma membrane that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate este [...]
Lbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000016168Lipopolysaccharide-binding protein; Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of a [...]
Celsr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016172Cadherin EGF LAG seven-pass G-type receptor 1; Receptor that may have an important role in cell/cell signaling during nervous system formation; Belongs to the G-protein coupled receptor 2 family. [...]
Fli1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016231Friend leukemia integration 1 transcription factor; Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'; Belongs to the ETS family.
N4bp2l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016279NEDD4-binding protein 2-like 1.
Camk1g protein networkhttps://string-db.org/network/10090.ENSMUSP00000016323Calcium/calmodulin-dependent protein kinase type 1G; Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription [...]
Hsd11b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016338Corticosteroid 11-beta-dehydrogenase isozyme 1; Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone.
Syt14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016344Synaptotagmin-14; May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent; Belongs to the synaptotagmin family.
Lonrf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016383LON peptidase N-terminal domain and RING finger protein 3.
Atp5e protein networkhttps://string-db.org/network/10090.ENSMUSP00000016396ATP synthase subunit epsilon, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membran [...]
Tubb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016399Tubulin beta-1 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha ch [...]
Ctsz protein networkhttps://string-db.org/network/10090.ENSMUSP00000016400Cathepsin Z; Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity). Capable of producing kinin potentiating peptides (By similarity).
Prelid3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000016401PRELI domain containing protein 3B; Belongs to the slowmo family.
Ube2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000016452Ubiquitin-conjugating enzyme E2 A; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it p [...]
Slc25a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016463ADP/ATP translocase 2, N-terminally processed; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated [...]
Atp1b4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016471Protein ATP1B4; May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit (By similarity) [...]
Ppdpf protein networkhttps://string-db.org/network/10090.ENSMUSP00000016488Pancreatic progenitor cell differentiation and proliferation factor; Probable regulator of exocrine pancreas development.
Srms protein networkhttps://string-db.org/network/10090.ENSMUSP00000016498Tyrosine-protein kinase Srms; Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues. Phosphorylation [...]
Ptk6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016511Protein-tyrosine kinase 6; Non-receptor tyrosine-protein kinase implicated in the regulation of a variety of signaling pathways that control the differentiation and maintenance of normal epitheli [...]
Nkap protein networkhttps://string-db.org/network/10090.ENSMUSP00000016553NF-kappa-B-activating protein; Acts as a transcriptional repressor. Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development. Also involved in [...]
Ndufa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016571NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved [...]
Cd34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016638Hematopoietic progenitor cell antigen CD34; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or dire [...]
Cd274 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016640Programmed cell death 1 ligand 1; Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation thre [...]
Lnx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016664Ligand of Numb protein X 2.
Dyrk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016670Dual specificity tyrosine-phosphorylation-regulated kinase 3; Dual-specificity protein kinase that promotes disassembly of several types of membraneless organelles during mitosis, such as stress [...]
Mapkapk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016672MAP kinase-activated protein kinase 2; Stress-activated serine/threonine-protein kinase involved in cytokine production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycl [...]
Il10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016673Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inf [...]
Cul4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000016680Cullin-4A; Core component of multiple cullin-RING-based E3 ubiquitin- protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a sca [...]
Foxred2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016696FAD-dependent oxidoreductase domain-containing protein 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endo [...]
Myh9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016771Myosin-9; During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial r [...]
Ift27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016781Intraflagellar transport protein 27 homolog; Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interactio [...]
Ttll1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016897Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carbo [...]
Ttll12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016901Tubulin--tyrosine ligase-like protein 12; Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues. [...]
Scube1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000016907Signal peptide, CUB and EGF-like domain-containing protein 1; Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
Serpinb1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000016951Leukocyte elastase inhibitor B; Regulates the activity of the neutrophil proteases. Forms only a stable complex with CTSG/Cathepsin G. During inflammation, limits the activity of inflammatory cas [...]
Mrps18c protein networkhttps://string-db.org/network/10090.ENSMUSP0000001697728S ribosomal protein S18c, mitochondrial; Belongs to the bacterial ribosomal protein bS18 family.
Tmprss6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017086Transmembrane protease serine 6; Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator [...]
Kctd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017090BTB/POZ domain-containing protein KCTD5; Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex (By similarity). Does not affect the function of Kv ch [...]
Pom121l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017126POM121-like protein 2; Belongs to the POM121 family.
Svs4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017142Seminal vesicle secretory protein 4.
Svs6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017144Seminal vesicle secretory protein 6.
Svs3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000017147Seminal vesicle secretory protein 3A; Component of the copulatory plug.
Svs5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017148Seminal vesicle secretory protein 5.
Rbpjl protein networkhttps://string-db.org/network/10090.ENSMUSP00000017151Recombining binding protein suppressor of hairless-like protein; Putative transcription factor, which cooperates with EBNA2 to activate transcription; Belongs to the Su(H) family.
Sdc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017153Syndecan-4; Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Belongs to the syndecan proteoglycan family.
Serpinb6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000017188Serpin B6; Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress. May be involved i [...]
Ccdc70 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017193Coiled-coil domain-containing protein 70.
Prl5a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017208Prolactin-5A1.
Krt24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017255Keratin, type I cytoskeletal 24; Belongs to the intermediate filament family.
Krt42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017270Keratin, type I cytoskeletal 42; Belongs to the intermediate filament family.
Rnd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017288Rho-related GTP-binding protein RhoE; Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
Brca1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017290Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA re [...]
Gast protein networkhttps://string-db.org/network/10090.ENSMUSP00000017309Big gastrin; Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and inc [...]
Coa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017332Cytochrome c oxidase assembly factor 3 homolog, mitochondrial; Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, t [...]
Zpbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017339Zona pellucida-binding protein 2; Is implicated in sperm-oocyte interaction during fertilization.
Gsdma protein networkhttps://string-db.org/network/10090.ENSMUSP00000017348Gasdermin-A; May promote pyroptosis. Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4 [...]
Med24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017354Mediator of RNA polymerase II transcription subunit 24; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Psmd3 protein networkhttps://string-db.org/network/10090.ENSMUSP0000001736526S proteasome non-ATPase regulatory subunit 3; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a k [...]
Casc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017384Protein CASC3; Required for pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on m [...]
Exosc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017408Exosome component 10; Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation [...]
Glod4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017430Glyoxalase domain-containing protein 4.
Dnttip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017443Deoxynucleotidyltransferase terminal-interacting protein 1; Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the conse [...]
Spint4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017454Kunitz-type protease inhibitor 4.
Mpp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017458MAGUK p55 subfamily member 2; Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity). In CA1 pyramidal neurons [...]
Ppy protein networkhttps://string-db.org/network/10090.ENSMUSP00000017460Pancreatic prohormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions.
Vtn protein networkhttps://string-db.org/network/10090.ENSMUSP00000017488Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of th [...]
Traf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017530TNF receptor-associated factor 4; Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the [...]
Aldoc protein networkhttps://string-db.org/network/10090.ENSMUSP00000017534Fructose-bisphosphate aldolase C; Belongs to the class I fructose-bisphosphate aldolase family.
Stac2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017544SH3 and cysteine-rich domain-containing protein 2; Plays a redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel [...]
Rpl19 protein networkhttps://string-db.org/network/10090.ENSMUSP0000001754860S ribosomal protein L19.
Nek8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017549Serine/threonine-protein kinase Nek8; Required for renal tubular integrity. May regulate local cytoskeletal structure in kidney tubule epithelial cells. May regulate ciliary biogenesis through ta [...]
Cacnb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017552Voltage-dependent L-type calcium channel subunit beta-1; Regulatory subunit of L-type calcium channels. Regulates the activity of L-type calcium channels that contain CACNA1A as pore- forming sub [...]
Psmd11 protein networkhttps://string-db.org/network/10090.ENSMUSP0000001757226S proteasome non-ATPase regulatory subunit 11; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a [...]
Rbfox3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017576RNA binding protein fox-1 homolog 3; Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-med [...]
C1qtnf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017590Complement C1q tumor necrosis factor-related protein 1.
Pipox protein networkhttps://string-db.org/network/10090.ENSMUSP00000017597Peroxisomal sarcosine oxidase; Metabolizes sarcosine, L-pipecolic acid and L-proline.
Cyba protein networkhttps://string-db.org/network/10090.ENSMUSP00000017604Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively gene [...]
Timp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017610Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhi [...]
Zc3h18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017622Zinc finger CCCH domain-containing protein 18.
Top2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000017629DNA topoisomerase 2-beta; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
Igfbp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017637Insulin-like growth factor-binding protein 4; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on [...]
Suz12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017692Polycomb protein Suz12; Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional re [...]
Atad5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017694ATPase family AAA domain-containing protein 5; Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is com [...]
Krt27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017732Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs).
Krt12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017741Keratin, type I cytoskeletal 12; May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity.
Krt20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017743Keratin, type I cytoskeletal 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the [...]
Tns4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017751Tensin-4; May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton May promote apoptosis, via its cleavage by caspase-3. Cytoplasm, [...]
Rab11fip4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017783Rab11 family-interacting protein 4; Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'addre [...]
Cd40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017799Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leadin [...]
Wsb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017821WD repeat and SOCS box-containing protein 1; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitina [...]
Rhbdl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017836Rhomboid-related protein 3; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 [...]
Rnf135 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017839E3 ubiquitin-protein ligase RNF135; E2-dependent E3 ubiquitin-protein ligase that functions as a RIG-I/DDX58 coreceptor in the sensing of viral RNAs in cell cytoplasm and the activation of the an [...]
Ada protein networkhttps://string-db.org/network/10090.ENSMUSP00000017841Adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by ext [...]
Serinc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017851Serine incorporator 3; Restriction factor required to restrict infectivity of gammaretroviruses: acts by inhibiting early step of viral infection and impairing the ability of the viral particle t [...]
Trp53tg5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017864Transformation-related protein 53 target 5.
Wfdc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017867WAP four-disulfide core domain protein 2; Broad range protease inhibitor.
Etv4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017868ETS translocation variant 4; Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'. May play a regulatory role during em [...]
Mmp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017881Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter [...]
Ghdc protein networkhttps://string-db.org/network/10090.ENSMUSP00000017891GH3 domain-containing protein; Belongs to the GH3 family.
Slc12a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017900Solute carrier family 12 member 7; Mediates electroneutral potassium-chloride cotransport when activated by cell swelling (By similarity). May mediate K(+) uptake into Deiters' cells in the cochl [...]
Zswim1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017908Zinc finger SWIM domain-containing protein 1.
Spata25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017911Spermatogenesis-associated protein 25; May play a role in spermatogenesis; Belongs to the SPATA25 family.
Crk protein networkhttps://string-db.org/network/10090.ENSMUSP00000017920Adapter molecule crk; [Isoform Crk-II]: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent mann [...]
Mlx protein networkhttps://string-db.org/network/10090.ENSMUSP00000017945Max-like protein X; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TC [...]
Retreg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017946Reticulophagy regulator 3; Mediates NRF1-enhanced neurite outgrowth. Belongs to the RETREG family.
Jph2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017961Junctophilin-2 N-terminal fragment; [Junctophilin-2]: Membrane-binding protein that provides a structural bridge between the plasma membrane and the sarcoplasmic reticulum and is required for nor [...]
Dhx58 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017974Probable ATP-dependent RNA helicase DHX58; Acts as a regulator of DDX58/RIG-I and IFIH1/MDA5 mediated antiviral signaling. Cannot initiate antiviral signaling as it lacks the CARD domain required [...]
Rab5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000017975Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular res [...]
Nkiras2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000017981NF-kappa-B inhibitor-interacting Ras-like protein 2; Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (N [...]
Ift52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018002Intraflagellar transport protein 52 homolog; Involved in ciliogenesis as part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the as [...]
Mybl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018005Myb-related protein B; Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene (By similarity).
Sgk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018012Serine/threonine-protein kinase Sgk2; Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proli [...]
Prl3c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018066Prolactin-3C1; Belongs to the somatotropin/prolactin family.
Hnf4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000018094Hepatocyte nuclear factor 4-alpha; Transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitatating t [...]
Ptgis protein networkhttps://string-db.org/network/10090.ENSMUSP00000018113Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family.
Cadps2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018122Calcium-dependent secretion activator 2; Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogen [...]
Ddx27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018143Probable ATP-dependent RNA helicase DDX27; Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 4 [...]
Rac3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018156Ras-related C3 botulinum toxin substrate 3; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of ef [...]
Rrp7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000018184Ribosomal RNA-processing protein 7 homolog A; Belongs to the RRP7 family.
Cyb5r3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018186NADH-cytochrome b5 reductase 3 membrane-bound form; Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.
Ints2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018212Integrator complex subunit 2; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The [...]
H2bc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018246Histone H2B type 1-C/E/G; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Hi [...]
Csnk1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000018274Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. I [...]
Stard3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018311StAR-related lipid transfer protein 3; Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes (By similarity). Creates contact site between the end [...]
Mfng protein networkhttps://string-db.org/network/10090.ENSMUSP00000018313Beta-1,3-N-acetylglucosaminyltransferase manic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of No [...]
Vmp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018315Vacuole membrane protein 1; Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death (By similarity). May be involved in the cytoplasmi [...]
Cdc73 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018337Parafibromin; Tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. May be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 [...]
Stk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018353Serine/threonine-protein kinase 4 18kDa subunit; Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by intern [...]
Gdf9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018382Growth/differentiation factor 9; Required for ovarian folliculogenesis; Belongs to the TGF-beta family.
Zcchc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018383Zinc finger CCHC domain-containing protein 10.
Krt33a protein networkhttps://string-db.org/network/10090.ENSMUSP00000018399Keratin, type I cuticular Ha3-I.
Prl8a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018403Prolactin family 8, subfamily a, member 2.
Tbx5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018407T-box transcription factor TBX5; DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation. Binds to the core DNA motif [...]
Psmb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018430Proteasome subunit beta type-6; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles wi [...]
Spag7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018431Sperm-associated antigen 7.
Pfn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018437Profilin-1; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By b [...]
Prpf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018449Pre-mRNA-processing-splicing factor 8; Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type splic [...]
Tomm34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018466Mitochondrial import receptor subunit TOM34; Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with [...]
Ywhab protein networkhttps://string-db.org/network/10090.ENSMUSP0000001847014-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of [...]
Stk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018476Serine/threonine-protein kinase 3 20kDa subunit; Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by intern [...]
Ksr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018478Kinase suppressor of Ras 1; Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Independently of its kinase act [...]
Zkscan6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018491Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Kpna2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018506Importin subunit alpha-1; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or biparti [...]
Cep95 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018516Centrosomal protein of 95 kDa.
Vezf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018521Vascular endothelial zinc finger 1.
Cuedc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018522CUE domain-containing protein 1.
Sept4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018544Septin-4; Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integr [...]
Mrm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018549rRNA methyltransferase 1, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1145 (Gm1145) in the 16S [...]
Myo1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000018561Unconventional myosin-Ib; Motor protein that may participate in process critical to neuronal development and function such as cell migration, neurite outgrowth and vesicular transport.
Drg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018568Developmentally-regulated GTP-binding protein 2; Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may b [...]
Dhx40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018569Probable ATP-dependent RNA helicase DHX40; Probable ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DEAH subfamily.
Ypel2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018571Protein yippee-like 2.
Akap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018572A-kinase anchor protein 1, mitochondrial; Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A. Anchors them to the cytoplasmic face of the mitochon [...]
Nol11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018577Nucleolar protein 11; Ribosome biogenesis factor. May be required for both optimal rDNA transcription and small subunit (SSU) pre-rRNA processing at sites A', A0, 1 and 2b (By similarity).
Rpain protein networkhttps://string-db.org/network/10090.ENSMUSP00000018593RPA-interacting protein; Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Sumoylation mediates the localization of RPA complex into the PML b [...]
Nos2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018610Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal act [...]
Kcnab3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018614Voltage-gated potassium channel subunit beta-3; Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv2.2 but n [...]
1700125H20Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000018623Uncharacterized protein C17orf64 homolog.
Appbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018625Amyloid protein-binding protein 2; May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface (By similarity).
Wnt9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000018630Protein Wnt-9b; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal embryonic [...]
Myh4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018632Myosin-4; Muscle contraction.
Adora2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000018644Adenosine receptor A2b; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family.
Ncor1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018645Nuclear receptor corepressor 1; Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin [...]
Trpv2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018651Transient receptor potential cation channel subfamily V member 2; Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF- I [...]
Cenpv protein networkhttps://string-db.org/network/10090.ENSMUSP00000018653Centromere protein V; Required for distribution of pericentromeric heterochromatin in interphase nuclei and for centromere formation and organization, chromosome alignment and cytokinesis; Belong [...]
Cwc25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018685Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family.
Pip4k2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000018691Phosphatidylinositol 5-phosphate 4-kinase type-2 beta; Participates in the biosynthesis of phosphatidylinositol 4,5- bisphosphate.
Ybx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018698Y-box-binding protein 2; Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box cons [...]
Slc2a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018710Solute carrier family 2, facilitated glucose transporter member 4; Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to i [...]
Gabarap protein networkhttps://string-db.org/network/10090.ENSMUSP00000018711Gamma-aminobutyric acid receptor-associated protein; Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved [...]
Cldn7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018713Claudin-7; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Phf23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018716PHD finger protein 23; Acts as a negative regulator of autophagy, through promoting ubiquitination and degradation of LRSAM1, an E3 ubiquitin ligase that promotes autophagy in response to starvat [...]
G3bp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018727Ras GTPase-activating protein-binding protein 1; ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by pro [...]
Sparc protein networkhttps://string-db.org/network/10090.ENSMUSP00000018737SPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cel [...]
Glra4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018739Glycine receptor subunit alpha-4; Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and bet [...]
Mief2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018743Mitochondrial dynamics protein MID49; Mitochondrial outer membrane protein which regulates mitochondrial organization. It is required for mitochondrial fission and promotes the recruitment and as [...]
Shmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018744Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine.
Tbx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018748T-box transcription factor TBX3; Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation. Acts as a negative regulator of PML function in ce [...]
Pdlim4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018755PDZ and LIM domain protein 4; Suppresses SRC activation by recognizing and binding to active SRC and facilitating PTPN13-mediated dephosphorylation of SRC 'Tyr-419' leading to its inactivation. I [...]
Mmp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018765Neutrophil collagenase; Can degrade fibrillar type I, II, and III collagens. May play a role in the degradation of collagen fibers during uterine involution.
Mmp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018767Matrilysin; Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase (By similarity).
Dusp14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018792Dual specificity protein phosphatase 14; Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases; Belongs to the protein-tyrosine phosphatase family. Non- recep [...]
Tada2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000018795Transcriptional adapter 2-alpha; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity). Required for the function of some acidic a [...]
Pnpo protein networkhttps://string-db.org/network/10090.ENSMUSP00000018803Pyridoxine-5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
Cog1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018805Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.
Copz2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018816Coatomer subunit zeta-2; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosyn [...]
Slc25a39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018821Solute carrier family 25 member 39; Required for normal heme biosynthesis; Belongs to the mitochondrial carrier (TC 2.A.29) family.
Aatf protein networkhttps://string-db.org/network/10090.ENSMUSP00000018841Protein AATF; May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F tar [...]
Lhx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018842LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.
Dync1h1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018851Cytoplasmic dynein 1 heavy chain 1; Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the f [...]
Ap2b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018875AP-2 complex subunit beta; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways [...]
Pex12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018877Peroxisome assembly protein 12; Required for protein import into peroxisomes.
Ndel1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018880Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least i [...]
Tnfsf13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018896Tumor necrosis factor ligand superfamily member 13; Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/ma [...]
Mpdu1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018905Mannose-P-dolichol utilization defect 1 protein; Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI ancho [...]
Fxr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018909Fragile X mental retardation syndrome-related protein 2; RNA-binding protein; Belongs to the FMR1 family.
Cd68 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018918Macrosialin; Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tiss [...]
Avpi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018965Arginine vasopressin-induced protein 1; May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling.
Sfrp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018966Secreted frizzled-related protein 5; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell gr [...]
Rad51d protein networkhttps://string-db.org/network/10090.ENSMUSP00000018985DNA repair protein RAD51 homolog 4; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. B [...]
Fndc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018988Fibronectin type III domain-containing protein 8.
Unc45b protein networkhttps://string-db.org/network/10090.ENSMUSP00000018989Protein unc-45 homolog B; Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is ne [...]
Pank3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018990Pantothenate kinase 3; Plays a role in the physiological regulation of coenzyme A (CoA) levels; Belongs to the type II pantothenate kinase family.
Rars protein networkhttps://string-db.org/network/10090.ENSMUSP00000018992Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion [...]
Wwc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000018993Protein KIBRA; Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting a [...]
Otop3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019006Proton channel OTOP3; Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellu [...]
Pnpla5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019012Patatin-like phospholipase domain-containing protein 5; Lipid hydrolase.
Mrpl45 protein networkhttps://string-db.org/network/10090.ENSMUSP0000001902639S ribosomal protein L45, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL45 family.
Slc22a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019044Solute carrier family 22 member 5; Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of c [...]
P4ha2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019050Prolyl 4-hydroxylase subunit alpha-2; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Alox12e protein networkhttps://string-db.org/network/10090.ENSMUSP00000019051Arachidonate 12-lipoxygenase, epidermal-type; Non-heme iron-containing dioxygenase that probably catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids gene [...]
Il3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019058Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell popul [...]
Csf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019060Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophag [...]
Tm4sf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019063Transmembrane 4 superfamily member 5.
Cxcl16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019064C-X-C motif chemokine 16; Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to [...]
Pelp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019065Proline-, glutamic acid- and leucine-rich protein 1; Coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence-specific transcripti [...]
Med11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019067Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Alox15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019068Arachidonate 15-lipoxygenase; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioa [...]
Heatr9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019069Protein HEATR9.
Ccl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019071C-C motif chemokine 6; CCL6(22-95) and CCL6(23-95) are potent chemoattractants. Belongs to the intercrine beta (chemokine CC) family.
Ccl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019074C-C motif chemokine 4; Monokine with inflammatory and chemokinetic properties.
Natd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019075Protein NATD1; Belongs to the NATD1 family.
Map2k3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019076Dual specificity mitogen-activated protein kinase kinase 3; Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a thr [...]
Scml2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019101Scm polycomb group protein-like 2.
Ywhah protein networkhttps://string-db.org/network/10090.ENSMUSP0000001910914-3-3 protein eta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognitio [...]
Hoxb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019117Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Sart3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019118Squamous cell carcinoma antigen recognized by T-cells 3; U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRN [...]
Slfn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019130Slfn3 protein.
Gga3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019135ADP-ribosylation factor-binding protein GGA3; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathr [...]
Slc35b4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019143UDP-xylose and UDP-N-acetylglucosamine transporter; Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into G [...]
Dalrd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019183DALR anticodon-binding domain-containing protein 3.
Cryaa protein networkhttps://string-db.org/network/10090.ENSMUSP00000019192Alpha-crystallin A chain; Contributes to the transparency and refractive index of the lens (By similarity). Has chaperone-like activity, preventing aggregation of various proteins under a wide ra [...]
Fis1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019198Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission me [...]
Plod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019199Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1; Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for [...]
Strn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019220Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family.
Mfsd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019224Major facilitator superfamily domain-containing protein 3.
Slc25a22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019226Mitochondrial glutamate carrier 1; Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+) (By similarity); Belongs to the mitochondri [...]
Med8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019229Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Me [...]
Atp6ap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019231V-type proton ATPase subunit S1; Accessory subunit of the proton-transporting vacuolar (V)- ATPase protein pump, which is required for luminal acidification of secretory vesicles. Guides the V-ty [...]
Dnase1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019232Deoxyribonuclease-1-like 1; Belongs to the DNase I family.
Aldh3a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019246Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, [...]
Cd22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019248B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially [...]
Ccl9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019266C-C motif chemokine 9; Monokine with inflammatory, pyrogenic and chemokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor ac [...]
Scrn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019268Secernin-1; Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity).
BC005537 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019276Uncharacterized protein C6orf62 homolog.
Cacng2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019290Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane a [...]
Psg28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019291Pregnancy-specific glycoprotein 28.
Tmem160 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019302Transmembrane protein 160.
Rab5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000019317Ras-related protein Rab-5C; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.
Mdh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019323Malate dehydrogenase, mitochondrial.
Rnf145 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019333RING finger protein 145; E3 ubiquitin ligase that catalyzes the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. In response to bacterial infection, nega [...]
Atp6v1e1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019354V-type proton ATPase subunit E 1; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intrace [...]
Mlh3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019378MutL homolog 3 (E coli).
Tecr protein networkhttps://string-db.org/network/10090.ENSMUSP00000019382Very-long-chain enoyl-CoA reductase; Involved in both the production of very long-chain fatty acids for sphingolipid synthesis and the degradation of the sphingosine moiety in sphingolipids throu [...]
Ripk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019386Receptor-interacting serine/threonine-protein kinase 4; Involved in stratified epithelial development (By similarity). It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B ac [...]
Map1s protein networkhttps://string-db.org/network/10090.ENSMUSP00000019405Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the m [...]
Dpep1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019422Dipeptidase 1; Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important rol [...]
Dsg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019426Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition fr [...]
Tmem129 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019439E3 ubiquitin-protein ligase TM129; E3 ubiquitin-protein ligase involved in ER-associated protein degradation, preferentially associates with the E2 enzyme UBE2J2. Exploited by viral US11 proteins [...]
Nop9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019441Nucleolar protein 9; Belongs to the NOP9 family.
Rnf31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019443E3 ubiquitin-protein ligase RNF31; E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in N [...]
Hsd17b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019445Estradiol 17-beta-dehydrogenase 1; Favors the reduction of estrogens and androgens. Uses preferentially NADH; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Psmc3ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000019447Homologous-pairing protein 2 homolog; Plays an important role in meiotic recombination. Stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The co [...]
Grb7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019456Growth factor receptor-bound protein 7; Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-st [...]
Noxo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019464NADPH oxidase organizer 1; Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures [...]
G6pc protein networkhttps://string-db.org/network/10090.ENSMUSP00000019469Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose pr [...]
Psme3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019470Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-ga [...]
Zfp687 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019482Zinc finger protein 687; May be involved in transcriptional regulation.
Gdpd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019503Glycerophosphoinositol inositolphosphodiesterase GDPD2; Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for othe [...]
D8Ertd738e protein networkhttps://string-db.org/network/10090.ENSMUSP00000019506Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy.
Sec14l4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019512SEC14-like protein 4; Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.
Calm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019514Calmodulin-1; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodul [...]
Nrbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019516Nuclear receptor-binding protein 2; May regulate apoptosis of neural progenitor cells during their differentiation.
Cops3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019517COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an esse [...]
Zfp874b protein networkhttps://string-db.org/network/10090.ENSMUSP00000019572Regulator of sex-limitation candidate 16.
Gipc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019577PDZ domain-containing protein GIPC1; Inhibits endothelial cell migration (in vitro). May be involved in G protein-linked signaling (By similarity); Belongs to the GIPC family.
Ptger1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019608Prostaglandin E2 receptor EP1 subtype; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messen [...]
Arhgef25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019611Rho guanine nucleotide exchange factor 25; May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a g [...]
Xab2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019614Pre-mRNA-splicing factor SYF1; Involved in pre-mRNA splicing as component of the spliceosome. Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing; Belongs to the c [...]
Cdc37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019615Hsp90 co-chaperone Cdc37, N-terminally processed; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of th [...]
Icam5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019616Intercellular adhesion molecule 5; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2); Belongs to the immunoglobulin superfamily. ICAM family.
Myh8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019625Myosin-8; Muscle contraction.
Cd70 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019633CD70 antigen; Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses. [...]
Cops6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019638COP9 signalosome complex subunit 6; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an esse [...]
Ubb protein networkhttps://string-db.org/network/10090.ENSMUSP00000019649Polyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either [...]
Zkscan1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019660Zinc finger protein with KRAB and SCAN domains 1; May be involved in transcriptional regulation.
Ap4m1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019662AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They co [...]
Armc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019679Armadillo repeat-containing protein 6.
Rcn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019683Reticulocalbin-3; Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum. Required for the proper biosynthesis and transport of pulmonary surfactan [...]
Haus5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019697HAUS augmin-like complex subunit 5; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex; Belongs to [...]
Dusp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019701Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
Arid3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000019708AT-rich interactive domain-containing protein 3A; Transcription factor involved in B-cell differentiation. Binds a VH promoter proximal site necessary for induced mu-heavy-chain transcription. Bi [...]
Pdk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019721[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial; Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation [...]
Ubxn6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019722UBX domain-containing protein 6; May negatively regulate the ATPase activity of VCP, an ATP- driven segregase that associates with different cofactors to control a wide variety of cellular proces [...]
Mydgf protein networkhttps://string-db.org/network/10090.ENSMUSP00000019723Myeloid-derived growth factor; Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair afte [...]
Plin3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019726Perilipin-3; Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network; Belongs to the perilipin family.
Cyb561 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019734Cytochrome b561; Secretory vesicle-specific electron transport protein.
Hoxd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019749Homeobox protein Hox-D8; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Sema6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000019791Semaphorin-6A; Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganizati [...]
Ccdc12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019803Coiled-coil domain-containing protein 12.
Plin5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019808Perilipin-5; Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to t [...]
Fmc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019833Protein FMC1 homolog; Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V).
Gle1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019859Nucleoporin GLE1; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear por [...]
Zfp451 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019861E3 SUMO-protein ligase ZNF451; E3 SUMO-protein ligase; has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins. Plays a role in protein SUMO2 modif [...]
L3hypdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000019862Trans-L-3-hydroxyproline dehydratase; Catalyzes the dehydration of trans-3-hydroxy-L-proline to delta-1-pyrroline-2-carboxylate (Pyr2C).
Calr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019876Calreticulin-3; CALR3 capacity for calcium-binding may be absent or much lower than that of CALR (By similarity). During spermatogenesis, may act as a lectin-independent chaperone for specific cl [...]
Leng1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019878Leukocyte receptor cluster member 1 homolog.
Polr2i protein networkhttps://string-db.org/network/10090.ENSMUSP00000019882DNA-directed RNA polymerase II subunit RPB9; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
Iyd protein networkhttps://string-db.org/network/10090.ENSMUSP00000019896Iodotyrosine deiodinase 1; Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodi [...]
Ccdc170 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019901Coiled-coil domain-containing 170.
Vip protein networkhttps://string-db.org/network/10090.ENSMUSP00000019906Vasoactive intestinal peptide; VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, sto [...]
Fbxo5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019907F-box only protein 5; Regulator of APC activity during mitotic and meiotic cell cycle. During mitotic cell cycle plays a role as both substrate and inhibitor of APC- FZR1 complex. During G1 phase [...]
Mtrf1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000019908Peptide chain release factor 1-like, mitochondrial; Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA [...]
Hdac2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019911Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic rep [...]
Frk protein networkhttps://string-db.org/network/10090.ENSMUSP00000019913Tyrosine-protein kinase FRK; Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr [...]
Rwdd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019917RWD domain-containing protein 1; Protects DRG2 from proteolytic degradation. Belongs to the RWDD1/GIR2 family.
Clvs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019920Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity).
Hey2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019924Hairy/enhancer-of-split related with YRPW motif protein 2; Transcriptional repressor which functions as a downstream effector of Notch signaling in cardiovascular development. Specifically requir [...]
Trmt11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019927tRNA (guanine(10)-N2)-methyltransferase homolog; Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide [...]
Lrp11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019931Low-density lipoprotein receptor-related protein 11.
Sec63 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019937Translocation protein SEC63 homolog; Mediates cotranslational and post-translational transport of certain precursor polypeptides across endoplasmic reticulum (ER). Proposed to play an auxiliary r [...]
Nr2e1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019938Nuclear receptor subfamily 2 group E member 1; Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in [...]
Snx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019939Sorting nexin-3; Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Also can bind phosphatidylinositol [...]
Aig1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019942Androgen-induced gene 1 protein; Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids (By similarity). Shows a preference for FAHFAs with [...]
Adat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019944tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs.
Pex3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019945Peroxisomal biogenesis factor 3; Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is nece [...]
Ltv1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019950Protein LTV1 homolog; Belongs to the LTV1 family.
Zc2hc1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000019954Zinc finger C2HC domain-containing protein 1B; Belongs to the ZC2HC1 family.
Cd164 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019962Sialomucin core protein 24; Sialomucin that may play a key role in hematopoiesis. May be involved in cell adhesion (By similarity). Promotes myogenesis by enhancing CXCR4-dependent cell motility. [...]
Smpd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019965Sphingomyelin phosphodiesterase 2; Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso- sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero- 3-phosphocholine (lyso-plate [...]
Mical1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019967[F-actin]-monooxygenase MICAL1; Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in [...]
Rab32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019974Ras-related protein Rab-32; Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchron [...]
Ddo protein networkhttps://string-db.org/network/10090.ENSMUSP00000019977D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family.
Rev3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000019986DNA polymerase zeta catalytic subunit; Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exo [...]
Traf3ip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019987cDNA fis, clone TRACH2006870,moderately similar to Homo sapiens adaptor protein CIKS mRNA.
Tube1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019991Tubulin epsilon chain; Belongs to the tubulin family.
Lama4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019992Laminin subunit alpha-4; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development [...]
Popdc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019994Popeye domain-containing protein 3; May play a role in the maintenance of heart function mediated, at least in part, through cAMP-binding.
Tnfaip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000019997Tumor necrosis factor alpha-induced protein 3; Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled b [...]
Perp protein networkhttps://string-db.org/network/10090.ENSMUSP00000019998P53 apoptosis effector related to PMP-22; Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. P [...]
Hebp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020000Heme-binding protein 2; Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions (By similarity). May have low affinity for [...]
Abracl protein networkhttps://string-db.org/network/10090.ENSMUSP00000020002Costars family protein ABRACL; Belongs to the costars family.
Fam184a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020003Family with sequence similarity 184, member A.
Asf1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020004Histone chaperone ASF1A; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly fact [...]
Gopc protein networkhttps://string-db.org/network/10090.ENSMUSP00000020008Golgi-associated PDZ and coiled-coil motif-containing protein; Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 curren [...]
Qrsl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020012Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. [...]
Nmbr protein networkhttps://string-db.org/network/10090.ENSMUSP00000020015Neuromedin-B receptor; Receptor for neuromedin-B; Belongs to the G-protein coupled receptor 1 family.
Gje1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020016Gap junction epsilon-1 protein; Mediates calcium-independent ATP release, suggesting activity as a hemichannel. Does not form functional gap junctions. May play a non-essential role in eye lens d [...]
Crybg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020017Crystallin beta-gamma domain-containing 1; Belongs to the beta/gamma-crystallin family.
Smpdl3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020022Acid sphingomyelinase-like phosphodiesterase 3a; Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP. Has in vitro activity with p-nitrophenyl-TMP. Has l [...]
Reep3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020023Receptor expression-enhancing protein 3; Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from ch [...]
Fabp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020024Fatty acid-binding protein, brain; B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for [...]
Serinc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020027Serine incorporator 1; Enhances the incorporation of serine into phosphatidylserine and sphingolipids; Belongs to the TDE1 family.
Echdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020034Ethylmalonyl-CoA decarboxylase; Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylma [...]
Nts protein networkhttps://string-db.org/network/10090.ENSMUSP00000020040Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle (By similarity).
Ros1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020045Proto-oncogene tyrosine-protein kinase ROS; Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. M [...]
Ccdc59 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020049Thyroid transcription factor 1-associated protein 26; Component of the transcription complexes of the pulmonary surfactant-associated protein-B (SFTPB) and -C (SFTPC). Enhances homeobox protein N [...]
Lin7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020057Protein lin-7 homolog A; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated mu [...]
Gprc6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020062G-protein coupled receptor family C group 6 member A; Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar am [...]
Fam162b protein networkhttps://string-db.org/network/10090.ENSMUSP00000020064Protein FAM162B.
Sim1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020071Single-minded homolog 1; Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult.
Lims1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020077LIM and senescent cell antigen-like-containing domain protein 1; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface re [...]
Ube2d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020085Ubiquitin-conjugating enzyme E2 D1; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Mediates [...]
Cdk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020099Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 pro [...]
Slc17a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020102Vesicular glutamate transporter 3; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic p [...]
Cabcoco1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020103Ciliary-associated calcium-binding coiled-coil protein 1; Calcium-binding protein. May be involved in the control of sperm flagellar movement.
Atp2b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020107Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellula [...]
Actr6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020109Actin-related protein 6; Belongs to the actin family. ARP6 subfamily.
Uhrf1bp1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000020112UHRF1-binding protein 1-like.
Poc1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000020113POC1 centriolar protein homolog B; Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps [...]
Dusp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020118Dual specificity protein phosphatase 6; Inactivates MAP kinases. Has a specificity for the ERK family (By similarity). Plays an important role in alleviating acute postoperative pain. Necessary f [...]
Tmpo protein networkhttps://string-db.org/network/10090.ENSMUSP00000020123Lamina-associated polypeptide 2, isoforms alpha/zeta; May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Plays an important role, together wit [...]
Ikbip protein networkhttps://string-db.org/network/10090.ENSMUSP00000020149Inhibitor of nuclear factor kappa-B kinase-interacting protein; Target of p53/TP53 with pro-apoptotic function.
Apaf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020157Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apopto [...]
Arg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020161Arginase-1; Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bio [...]
Nedd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020163Protein NEDD1; Required for mitosis progression. Promotes the nucleation of microtubules from the spindle (By similarity). May play an important role during the embryonic development and differen [...]
Enpp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020169Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basop [...]
Ccn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020171CCN family member 2; Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin- a [...]
Pex7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020182Peroxisomal targeting signal 2 receptor; Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import.
Il20ra protein networkhttps://string-db.org/network/10090.ENSMUSP00000020185Interleukin-20 receptor subunit alpha; The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26 (By similarity).
Ifngr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020188Interferon gamma receptor 1; Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway (By similar [...]
Vnn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020190Vascular non-inflammatory molecule 3; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cystea [...]
Snrpf protein networkhttps://string-db.org/network/10090.ENSMUSP00000020203Small nuclear ribonucleoprotein F; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, [...]
Ntn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020204Netrin-4; May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants.
Fgd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020208FYVE, RhoGEF and PH domain-containing protein 6; May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating [...]
Cep83 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020212Centrosomal protein of 83 kDa; Component of the distal appendage region of the centriole involved in the initiation of primary cilium assembly. May collaborate with IFT20 in the trafficking of ci [...]
Socs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020215Suppressor of cytokine signaling 2; SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in [...]
Nudt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020217Diphosphoinositol polyphosphate phosphohydrolase 2; Cleaves a beta-phosphate from the diphosphate groups in PP- InsP5 (diphosphoinositol pentakisphosphate), PP-InsP4 and [PP]2-InsP4 (bisdiphospho [...]
Nuak1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020220NUAK family SNF1-like kinase 1; Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progres [...]
Tcp11l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020223T-complex protein 11-like protein 2; Belongs to the TCP11 family.
Cry1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020227Cryptochrome-1; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes thro [...]
Timp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020234Metalloproteinase inhibitor 3; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-sp [...]
Hsp90b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020238Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in [...]
Pah protein networkhttps://string-db.org/network/10090.ENSMUSP00000020241Phenylalanine-4-hydroxylase; Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine. Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Ascl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020243Achaete-scute homolog 1; Transcription factor that plays a key role in neuronal differentiation: acts as a pioneer transcription factor, accessing closed chromatin to allow other factors to bind [...]
Washc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020248WASH complex subunit 3; Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in [...]
Dram1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020249DNA damage-regulated autophagy modulator protein 1; Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy (By simi [...]
Gnptab protein networkhttps://string-db.org/network/10090.ENSMUSP00000020251N-acetylglucosamine-1-phosphotransferase subunits alpha/beta; Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. M6P residu [...]
Sycp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020252Synaptonemal complex protein 3; Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in mal [...]
Slc5a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020255Sodium-coupled monocarboxylate transporter 1; Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)- dependent sodium-coupled solute transporter, including transport of monocarboxylates (shor [...]
Herc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020258Probable E3 ubiquitin-protein ligase HERC4; Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon ma [...]
Pbld2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020262Phenazine biosynthesis-like domain-containing protein 2; Belongs to the PhzF family.
Hnrnph3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020263Heterogeneous nuclear ribonucleoprotein H3.
Ccar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020268Cell division cycle and apoptosis regulator protein 1; Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals [...]
Ddx50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020270ATP-dependent RNA helicase DDX50.
Supv3l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020273ATP-dependent RNA helicase SUPV3L1, mitochondrial; Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang dou [...]
Hkdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020277Hexokinase HKDC1; Catalyzes the phosphorylation of hexose to hexose 6- phosphate, although at very low level compared to other hexokinases (By similarity). Has low glucose phosphorylating activit [...]
Tacr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020278Substance-K receptor; This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger [...]
Macroh2a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020283Core histone macro-H2A.2; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limitin [...]
Tysnd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020284Peroxisomal leader peptide-processing protease, 10 kDa form; Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processe [...]
Sar1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020285GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps b [...]
Ppa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020286Inorganic pyrophosphatase; Belongs to the PPase family.
Npffr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020287Neuropeptide FF receptor 1; Belongs to the G-protein coupled receptor 1 family.
Eif4ebp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020288Eukaryotic translation initiation factor 4E-binding protein 2; Repressor of translation initiation involved in synaptic plasticity, learning and memory formation. Regulates EIF4E activity by prev [...]
Pald1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020289Paladin.
Pcbd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020298Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator [...]
Vsir protein networkhttps://string-db.org/network/10090.ENSMUSP00000020301V-type immunoglobulin domain-containing suppressor of T-cell activation; Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhi [...]
Anapc16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020307Anaphase-promoting complex subunit 16; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the [...]
Ddit4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020308DNA damage-inducible transcript 4 protein; Regulates cell growth, proliferation and survival via inhibition of the activity of the mammalian target of rapamycin complex 1 (mTORC1). Inhibition of [...]
Micu1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020311Calcium uptake protein 1, mitochondrial; Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains. MICU1 and MICU2 form a disulfide-linked heterodi [...]
Mcu protein networkhttps://string-db.org/network/10090.ENSMUSP00000020312Calcium uniporter protein, mitochondrial; Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes the pore-forming and calcium-conducting subuni [...]
Cand1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020315Cullin-associated NEDD8-dissociated protein 1; Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate- recognition F-box su [...]
Tbk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020316Serine/threonine-protein kinase TBK1; Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents. Following activation of toll-like receptors by v [...]
Pno1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020317RNA-binding protein PNO1; Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA. Belongs to the PNO1 family.
Avpr1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020323Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Invol [...]
Egfr protein networkhttps://string-db.org/network/10090.ENSMUSP00000020329Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular resp [...]
Tbc1d15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020339TBC1 domain family member 15; Acts as a GTPase activating protein for RAB7A. Does not act on RAB4, RAB5 or RAB6.
Pcsk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020340Proprotein convertase subtilisin/kexin type 4; Proprotein convertase involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. I [...]
2310011J03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000020341UPF0449 protein C19orf25 homolog; Belongs to the UPF0449 family.
Rab21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020343Ras-related protein Rab-21; Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell a [...]
Apc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020349Adenomatous polyposis coli protein 2; Stabilizes microtubules and may regulate actin fiber dynamics through the activation of Rho family GTPases. May also function in Wnt signaling by promoting t [...]
Lgr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020350Leucine-rich repeat-containing G-protein coupled receptor 5; Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epitheli [...]
Gamt protein networkhttps://string-db.org/network/10090.ENSMUSP00000020359Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Important in nervous system development.
Kcnmb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020362Calcium-activated potassium channel subunit beta-1; Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, [...]
Pwwp3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020365PWWP domain-containing DNA repair factor 3A; Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by T [...]
Gabrp protein networkhttps://string-db.org/network/10090.ENSMUSP00000020366Gamma-aminobutyric acid receptor subunit pi; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and o [...]
Uqcr11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020372Cytochrome b-c1 complex subunit 10; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which d [...]
Rab3ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000020375Rab-3A-interacting protein; Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their [...]
Best3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020378Bestrophin-3; Forms calcium-sensitive chloride channels. Permeable to bicarbonate (By similarity); Belongs to the bestrophin family.
Frs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020381Fibroblast growth factor receptor substrate 2; Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinase [...]
Yeats4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020382YEATS domain-containing protein 4; Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucl [...]
Atp8b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020383Phospholipid-transporting ATPase IK; P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membran [...]
9530003J23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000020392RIKEN cDNA 9530003J23 gene; Belongs to the glycosyl hydrolase 22 family.
Snrpd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020397Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, [...]
Cpm protein networkhttps://string-db.org/network/10090.ENSMUSP00000020399Carboxypeptidase M; Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth fac [...]
Csrp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020403Cysteine and glycine-rich protein 2; Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in [...]
Mdm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020408E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73- mediated cel [...]
Osbpl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020411Oxysterol-binding protein-related protein 5; Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylser [...]
Zpbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000020413Zona pellucida-binding protein 1; Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization. Belongs to the zona pellucida-bindin [...]
Ap3d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020420AP-3 complex subunit delta-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral str [...]
Glipr1l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020434GLIPR1-like protein 2; Belongs to the CRISP family.
Wif1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020439Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
Timm13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020440Mitochondrial import inner membrane translocase subunit Tim13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into t [...]
Llph protein networkhttps://string-db.org/network/10090.ENSMUSP00000020444Protein LLP homolog; In hippocampal neurons, regulates dendritic and spine growth and synaptic transmission.
Tmbim4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020446Protein lifeguard 4; Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphos [...]
Irak3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020448Interleukin-1 receptor-associated kinase 3; Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or s [...]
Helb protein networkhttps://string-db.org/network/10090.ENSMUSP00000020449DNA helicase B; 5'-3' DNA helicase involved in DNA damage response by acting as an inhibitor of DNA end resection. Recruitment to single-stranded DNA (ssDNA) following DNA damage leads to inhibit [...]
Slc5a4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020450Solute carrier family 5 member 4A; Has sugar-induced sodium-independent electrogenic activity. Generation of glucose-induced inward currents is pH-dependent, with activity in acidic conditions (p [...]
Hmg20b protein networkhttps://string-db.org/network/10090.ENSMUSP00000020454High mobility group 20B; Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promot [...]
4930404N11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000020456Uncharacterized protein C19orf71 homolog.
Nfic protein networkhttps://string-db.org/network/10090.ENSMUSP00000020461Nuclear factor 1 C-type; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These [...]
Ncln protein networkhttps://string-db.org/network/10090.ENSMUSP00000020463Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.
Hcfc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020478Host cell factor 2.
Glt8d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020485Glycosyltransferase 8 domain-containing protein 2.
D10Wsu102e protein networkhttps://string-db.org/network/10090.ENSMUSP00000020488Uncharacterized protein C12orf45 homolog.
Wdr82 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020490WD repeat-containing protein 82; Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4 [...]
Pofut2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020493GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2 [...]
Aldh1l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020497Mitochondrial 10-formyltetrahydrofolate dehydrogenase; In the N-terminal section; belongs to the GART family.
Appl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020500DCC-interacting protein 13-beta; Multifunctional adapter protein that binds to various membrane receptors, nuclear factors and signaling proteins to regulate many processes, such as cell prolifer [...]
Slc36a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020502Proton-coupled amino acid transporter 3; Belongs to the amino acid/polyamine transporter 2 family.
Hint1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020504Histidine triad nucleotide-binding protein 1; Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monopho [...]
Fgf18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020507Fibroblast growth factor 18; Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimu [...]
Smim23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020508Small integral membrane protein 23.
Papolg protein networkhttps://string-db.org/network/10090.ENSMUSP00000020513Poly(A) polymerase gamma; Responsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclea [...]
Pfkl protein networkhttps://string-db.org/network/10090.ENSMUSP00000020522ATP-dependent 6-phosphofructokinase, liver type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (By similarit [...]
Pex13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020523Peroxisomal membrane protein PEX13; Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10 [...]
Rhbdf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020524Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migr [...]
Mpg protein networkhttps://string-db.org/network/10090.ENSMUSP00000020528DNA-3-methyladenine glycosylase; Hydrolysis of the deoxyribose N-glycosidic bond to excise 3- methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
Ahsa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020529Activator of 90 kDa heat shock protein ATPase homolog 2; Co-chaperone that stimulates HSP90 ATPase activity. Belongs to the AHA1 family.
Nprl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020530GATOR complex protein NPRL3; As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrol [...]
Hba-x protein networkhttps://string-db.org/network/10090.ENSMUSP00000020531Hemoglobin subunit zeta; The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin; Belongs to the globin family.
Hbq1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020535Hemoglobin, theta 1A; Belongs to the globin family.
Nsg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020537Neuronal vesicle trafficking-associated protein 2.
Cpeb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020543Cytoplasmic polyadenylation element-binding protein 4; Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consens [...]
Stc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020546Stanniocalcin-2; Has an anti-hypocalcemic action on calcium and phosphate homeostasis; Belongs to the stanniocalcin family.
Vmn2r81 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020547EC1-V2R pheromone receptor protein.
Gzmm protein networkhttps://string-db.org/network/10090.ENSMUSP00000020549Granzyme M (Lymphocyte Met-ase 1); Belongs to the peptidase S1 family.
Cdc34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020550Ubiquitin-conjugating enzyme E2 R1; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Cooperat [...]
Asb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020551Ankyrin repeat and SOCS box protein 3; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquiti [...]
Tpgs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020552Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum.
Madcam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020554Mucosal addressin cell adhesion molecule 1; Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and [...]
Shc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020564SHC-transforming protein 2; Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activate [...]
Theg protein networkhttps://string-db.org/network/10090.ENSMUSP00000020566Testicular haploid expressed gene protein; May be involved (but not essential) in spermatogenesis.
Wdpcp protein networkhttps://string-db.org/network/10090.ENSMUSP00000020568WD repeat-containing and planar cell polarity effector protein fritz homolog; Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both cilio [...]
Fstl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020575Follistatin-related protein 3; The secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- a [...]
Ccng1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020576Cyclin-G1; May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular [...]
Nudcd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020578NudC domain-containing protein 2; May regulate the LIS1/dynein pathway by stabilizing LIS1 with Hsp90 chaperone.
Hmmr protein networkhttps://string-db.org/network/10090.ENSMUSP00000020579Hyaluronan mediated motility receptor; Receptor for hyaluronic acid (HA). Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the PTK2 [...]
Polrmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000020580DNA-directed RNA polymerase, mitochondrial; DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates. Compo [...]
Slc22a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020586Solute carrier family 22 member 4; Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations suc [...]
Ppp2ca protein networkhttps://string-db.org/network/10090.ENSMUSP00000020608Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase [...]
Flt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020617Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the [...]
Gfpt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020629Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N [...]
Hspa4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020630Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family.
Rack1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020640Receptor of activated protein C kinase 1, N-terminally processed; Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a [...]
Rufy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020643RUN and FYVE domain-containing protein 1; Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.
Mrnip protein networkhttps://string-db.org/network/10090.ENSMUSP00000020647MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes [...]
Rad50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020649DNA repair protein RAD50; Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The compl [...]
Il13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020650Interleukin-13; Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses [...]
Sar1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000020653GTP-binding protein SAR1b; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the [...]
Jade2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020655E3 ubiquitin-protein ligase Jade-2; Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk [...]
Ube2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000020657Ubiquitin-conjugating enzyme E2 B; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it p [...]
Kremen1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020662Kremen protein 1; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. In the absence of DKK1, [...]
Havcr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020668Hepatitis A virus cellular receptor 2 homolog; Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on s [...]
Fabp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020672Gastrotropin; Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes. Stim [...]
Upp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020677Uridine phosphorylase 1; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as [...]
Nipal4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020679Magnesium transporter NIPA4; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+) and Co(2+) but to a much less extent than Mg(2+). May be a rece [...]
Slu7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020681Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon [...]
Hus1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020683Checkpoint protein HUS1; Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17 [...]
Btg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020692Protein BTG2; Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent ma [...]
Tns3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020695Tensin-3; May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of I [...]
Castor1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020699Cytosolic arginine sensor for mTORC1 subunit 1; Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer [...]
Igfbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020702Insulin-like growth factor-binding protein 3; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on [...]
Igfbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020704Insulin-like growth factor-binding protein 1; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on [...]
Pes1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020705Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family.
Adcy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020706Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels. May be invo [...]
Gabra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020707Gamma-aminobutyric acid receptor subunit alpha-1; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. [...]
4921536K21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000020712Uncharacterized protein C5orf52 homolog.
Arf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020717ADP-ribosylation factor 5; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
2310033P09Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000020719Multiple myeloma tumor-associated protein 2 homolog.
Drg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020741Developmentally-regulated GTP-binding protein 1; Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. Appears to have an intrinsic GTPase activity that is [...]
Clhc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020753Clathrin heavy chain linker domain-containing protein 1.
Cfap36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020754Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family.
Ppp4r3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000020755Serine/threonine-protein phosphatase 4 regulatory subunit 3B; Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule org [...]
Pnpt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020756Polyribonucleotide nucleotidyltransferase 1, mitochondrial; RNA-binding protein implicated in numerous RNA metabolic processes. Catalyzes the phosphorolysis of single-stranded polyribonucleotides [...]
Efemp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020759EGF-containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in [...]
Polm protein networkhttps://string-db.org/network/10090.ENSMUSP00000020767DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain ge [...]
Pgam2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020768Phosphoglycerate mutase 2; Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but w [...]
Dbnl protein networkhttps://string-db.org/network/10090.ENSMUSP00000020769Drebrin-like protein; Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formati [...]
Dynll2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020775Dynein light chain 2, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to [...]
Ccdc117 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020776Coiled-coil domain-containing protein 117.
Mpo protein networkhttps://string-db.org/network/10090.ENSMUSP00000020779Myeloperoxidase heavy chain; Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, [...]
Btnl10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020792Butyrophilin-like protein 10; Belongs to the immunoglobulin superfamily. BTN/MOG family.
Ska2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020794Spindle and kinetochore-associated protein 2; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Require [...]
Smg8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020801Protein SMG8; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SM [...]
Gdpd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020804Lysophospholipase D GDPD1; Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl- sn-glycero-3-phosphocholine ( [...]
Mrpl22 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002082039S ribosomal protein L22, mitochondrial; Belongs to the universal ribosomal protein uL22 family.
Tubd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020821Tubulin delta chain; Acts as a positive regulator of hedgehog signaling and regulates ciliary function. Belongs to the tubulin family.
Sap30l protein networkhttps://string-db.org/network/10090.ENSMUSP00000020826Histone deacetylase complex subunit SAP30L; Functions as transcription repressor, probably via its interaction with histone deacetylase complexes. Involved in the functional recruitment of the cl [...]
Rnft1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020827E3 ubiquitin-protein ligase RNFT1; E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate [...]
Mfap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020830Microfibril-associated glycoprotein 3; Component of the elastin-associated microfibrils.
Ppm1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000020835Protein phosphatase 1D; Involved in the negative regulation of p53 expression. Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-1 [...]
Srebf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020846Processed sterol regulatory element-binding protein 1; Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to [...]
Cox11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020851Cytochrome c oxidase assembly protein COX11, mitochondrial; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B [...]
Lrrc72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020853Leucine-rich repeat-containing 72.
Bzw2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020856Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation.
Pctp protein networkhttps://string-db.org/network/10090.ENSMUSP00000020864Phosphatidylcholine transfer protein; Catalyzes the transfer of phosphatidylcholine between membranes. Binds a single lipid molecule.
Twistnb protein networkhttps://string-db.org/network/10090.ENSMUSP00000020877DNA-directed RNA polymerase I subunit RPA43; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
Efcab10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020878EF-hand calcium-binding domain-containing protein 10.
Atp6v1c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020884V-type proton ATPase subunit C 2; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a sp [...]
Nampt protein networkhttps://string-db.org/network/10090.ENSMUSP00000020886Nicotinamide phosphoribosyltransferase; The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, [...]
Tspan13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020896Tetraspanin-13.
Agr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020898Anterior gradient protein 2 homolog; Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a [...]
Matn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020899Matrilin-3; Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.
Rock2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020904Rho-associated protein kinase 2; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organizat [...]
E2f6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020908Transcription factor E2F6; Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'- TTTC[CG]CGC-3'. Has a preference for the 5'-TTTC [...]
Laptm4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020909Lysosomal-associated transmembrane protein 4A; May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound comp [...]
Sdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020911Syndecan-1; Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert w [...]
Rgs9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020920Regulator of G-protein signaling 9; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to GN [...]
Trib2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020922Tribbles homolog 2; Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity (By similarity).
Lratd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020926Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family.
Hs1bp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020927HCLS1-binding protein 3; May be a modulator of IL-2 signaling.
Arsg protein networkhttps://string-db.org/network/10090.ENSMUSP00000020928Arylsulfatase G; Displays arylsulfatase activity with pseudosubstrates at acidic pH, such as p-nitrocatechol sulfate. Belongs to the sulfatase family.
Gna13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020930Guanine nucleotide-binding protein subunit alpha-13; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Activat [...]
Smc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020931Structural maintenance of chromosomes protein 6; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may pro [...]
Fam20a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020938Pseudokinase FAM20A; Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM2 [...]
Nrcam protein networkhttps://string-db.org/network/10090.ENSMUSP00000020939Neuronal cell adhesion molecule; Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth [...]
Rdh14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020947Retinol dehydrogenase 14; Retinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol. Shows a very weak activity towards 13-cis-ret [...]
Abca8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000020948ATP-binding cassette sub-family A member 8-B; ATP-dependent lipophilic drug transporter; Belongs to the ABC transporter superfamily. ABCA family.
Map2k6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020949Dual specificity mitogen-activated protein kinase kinase 6; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. With MAP3K3/MKK3, c [...]
Trappc12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020954Trafficking protein particle complex subunit 12; Component of the TRAPP complex, which is involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage. Also plays a role [...]
Adi1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000209571,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also d [...]
Klhl29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020958Kelch-like protein 29.
Rnaseh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020959Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid forma [...]
Ubxn2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020962UBX domain-containing protein 2A.
Fkbp1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000020964Peptidyl-prolyl cis-trans isomerase FKBP1B; Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catal [...]
Allc protein networkhttps://string-db.org/network/10090.ENSMUSP00000020965Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals.
Cmpk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020969UMP-CMP kinase 2, mitochondrial; May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs [...]
Rsad2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020970Radical S-adenosyl methionine domain-containing protein 2; Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced [...]
Rnf144a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020971E3 ubiquitin-protein ligase RNF144A; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly trans [...]
Dus4l protein networkhttps://string-db.org/network/10090.ENSMUSP00000020977tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the Dus family. Dus4 subfamily.
Rrm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020980Ribonucleoside-diphosphate reductase subunit M2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. In [...]
Klf11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020982Krueppel-like factor 11; Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like [...]
Dnajc27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020986DnaJ homolog subfamily C member 27; GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by associati [...]
Dnmt3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000020991DNA (cytosine-5)-methyltransferase 3A; Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coord [...]
Sh3yl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000020997SH3 domain-containing YSC84-like protein 1.
Kif3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000020999Kinesin-like protein KIF3C; Microtubule-based anterograde translocator for membranous organelles.
Rab10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021001Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity) [...]
Sntg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021004Gamma-2-syntrophin; Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystro [...]
Tpo protein networkhttps://string-db.org/network/10090.ENSMUSP00000021005Thyroid peroxidase; Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
Ccl7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021011C-C motif chemokine 7; Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity (By similarity).
Hnf1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000021016Hepatocyte nuclear factor 1-beta; Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTAAC-3'; Belongs to the HNF1 homeobox family.
Taf15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021018TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor.
Itgb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021028Integrin beta-3; Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitr [...]
Efcab3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021029EF-hand calcium-binding domain-containing protein 3.
Mettl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021030tRNA N(3)-methylcytidine methyltransferase METTL2; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of t [...]
Cct6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000021040T-complex protein 1 subunit zeta-2; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis; Belongs to the [...]
Asic2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021045Acid-sensing ion channel 2; Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Gener [...]
Ddx42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021046ATP-dependent RNA helicase DDX42; ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence [...]
Ftsj3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021048pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
Psmc5 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002104926S proteasome regulatory subunit 8; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in [...]
Adap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021050Arf-GAP with dual PH domain-containing protein 2; GTPase-activating protein for the ADP ribosylation factor family (Potential). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inosi [...]
Smarcd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021052SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alter [...]
Scn4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000021056Sodium channel protein type 4 subunit alpha; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Altern [...]
Polg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021060DNA polymerase subunit gamma-2, mitochondrial; Mitochondrial polymerase processivity subunit. Stimulates the polymerase and exonuclease activities, and increases the processivity of the enzyme. B [...]
Ddx5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021062Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a [...]
Psmd12 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002106326S proteasome non-ATPase regulatory subunit 12; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a [...]
Cacng1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021065Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactiv [...]
Cacng4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021066Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and ga [...]
Rab37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021076Ras-related protein Rab-37.
Slc9a3r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021077Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the acti [...]
Fdxr protein networkhttps://string-db.org/network/10090.ENSMUSP00000021078NADPH:adrenodoxin oxidoreductase, mitochondrial; Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic [...]
Nt5c protein networkhttps://string-db.org/network/10090.ENSMUSP000000210825'(3')-deoxyribonucleotidase, cytosolic type; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and l [...]
Jpt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021083Jupiter microtubule associated homolog 1, N-terminally processed; Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppressio [...]
Nup85 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021085Nuclear pore complex protein Nup85; Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex play [...]
Grb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021090Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway; Belongs to the GRB2/sem-5/DRK fam [...]
Pafah1b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021091Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule [...]
Recql5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021097ATP-dependent DNA helicase Q5; DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to [...]
Galk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021114Galactokinase; Major enzyme for galactose metabolism; Belongs to the GHMP kinase family. GalK subfamily.
Unk protein networkhttps://string-db.org/network/10090.ENSMUSP00000021116RING finger protein unkempt homolog; Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during em [...]
Trim47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021120E3 ubiquitin-protein ligase TRIM47; E3 ubiquitin-protein ligase that mediates the ubiquitination and proteasomal degradation of CYLD; Belongs to the TRIM/RBCC family.
Ten1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021130CST complex subunit TEN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication [...]
Srp68 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021133Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S [...]
Tsen54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021134tRNA-splicing endonuclease subunit Sen54; Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. I [...]
Ncbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021135Nuclear cap-binding protein subunit 3; Associates with NCBP1/CBP80 to form an alternative cap- binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking [...]
P2rx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021141P2X purinoceptor 1; Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to b [...]
Atp2a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021142Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytoso [...]
Exoc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021147Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeti [...]
Ube2g1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021148Ubiquitin-conjugating enzyme E2 G1, N-terminally processed; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as [...]
Tekt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021155Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity).
Med31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021157Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Txndc17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021158Thioredoxin domain-containing protein 17; Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze [...]
Slc13a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021161Solute carrier family 13 member 5; High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate ra [...]
Pimreg protein networkhttps://string-db.org/network/10090.ENSMUSP00000021164Protein PIMREG; During mitosis, may play a role in the metaphase-to-anaphase transition.
Cygb protein networkhttps://string-db.org/network/10090.ENSMUSP00000021166Cytoglobin; May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer; Belongs to the globin family.
Mxra7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021170Matrix-remodeling-associated protein 7.
Mfsd11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021173UNC93-like protein MFSD11.
Sec14l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021177SEC14-like protein 1; May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic se [...]
Vmo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021179Vitelline membrane outer layer protein 1 homolog.
Eral1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021183GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide [...]
Dhrs13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021187Dehydrogenase/reductase SDR family member 13; Putative oxidoreductase.
Blmh protein networkhttps://string-db.org/network/10090.ENSMUSP00000021197Bleomycin hydrolase; The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of [...]
Cpd protein networkhttps://string-db.org/network/10090.ENSMUSP00000021201Carboxypeptidase D; Belongs to the peptidase M14 family.
Timm22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021203Mitochondrial import inner membrane translocase subunit Tim22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins [...]
Nxn protein networkhttps://string-db.org/network/10090.ENSMUSP00000021204Nucleoredoxin; Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a tra [...]
Rflnb protein networkhttps://string-db.org/network/10090.ENSMUSP00000021207Refilin-B; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in the formation of cartilaginous skeletal elem [...]
Doc2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000021209Double C2-like domain-containing protein beta; Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium- dependent manner and [...]
Nme2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021217Nucleoside diphosphate kinase B; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism [...]
Luc7l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021226Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing (By similarity); Belongs to the Luc7 family.
Abcc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021231Canalicular multispecific organic anion transporter 2; May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export o [...]
Lrrc59 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021239Leucine-rich repeat-containing protein 59, N-terminally processed; Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating inter [...]
Cdc34b protein networkhttps://string-db.org/network/10090.ENSMUSP00000021240Cell division cycle 34B; Belongs to the ubiquitin-conjugating enzyme family.
Dlx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021241Homeobox protein DLX-4; May play a role in determining the production of hemoglobin S. May act as a repressor. During embryonic development, plays a role in palatogenesis; Belongs to the distal-l [...]
Tac4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021242Tachykinin-4; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscle [...]
Slc35b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021243Solute carrier family 35 member B1; Probable sugar transporter; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
Snx11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021246Sorting nexin-11; Phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes; Belongs to the sorting nexin family.
Scrn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021249Secernin-2; Belongs to the peptidase C69 family. Secernin subfamily.
Lrrc46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021251Leucine-rich repeat-containing protein 46.
Gucy2e protein networkhttps://string-db.org/network/10090.ENSMUSP00000021259Retinal guanylyl cyclase 1; Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May al [...]
Alox8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021262Arachidonate 8S-lipoxygenase; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioa [...]
Aloxe3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021268Hydroperoxide isomerase ALOXE3; Non-heme iron-containing lipoxygenase which is atypical in that it displays a prominent hydroperoxide isomerase activity and a reduced dioxygenase activity compare [...]
Per1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021271Period circadian protein homolog 1; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiolo [...]
Vamp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021273Vesicle-associated membrane protein 2; Involved in the targeting and/or fusion of transport vesicles to their target membrane. Modulates the gating characteristics of the delayed rectifier voltag [...]
Aurkb protein networkhttps://string-db.org/network/10090.ENSMUSP00000021277Aurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions a [...]
Pfas protein networkhttps://string-db.org/network/10090.ENSMUSP00000021282Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ri [...]
Pik3r5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021283Phosphoinositide 3-kinase regulatory subunit 5; Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-ga [...]
Stx8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021285Syntaxin-8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis- Golgi membranes to the ER; Belongs to the syntaxin fami [...]
Cfap52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021287Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family.
Usp43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021288Ubiquitin carboxyl-terminal hydrolase 43; May recognize and hydrolyze the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that [...]
Rcvrn protein networkhttps://string-db.org/network/10090.ENSMUSP00000021290Recoverin; Acts as a calcium sensor and regulates phototransduction of cone and rod photoreceptor cells (By similarity). Modulates light sensitivity of cone photoreceptor in dark and dim conditio [...]
Tmem101 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021296Transmembrane protein 101; May activate NF-kappa-B signaling pathways.
Lsm12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021297Protein LSM12 homolog; Belongs to the LSM12 family.
Higd1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000021302HIG1 domain family member 1B.
Eftud2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021306116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes [...]
Ccdc103 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021307Coiled-coil domain-containing protein 103; Dynein-attachment factor required for cilia motility.
Kif18b protein networkhttps://string-db.org/network/10090.ENSMUSP00000021311Kinesin-like protein KIF18B; In complex with KIF2C, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Its major role may be to transport KIF2C and/or MAPRE1 alo [...]
Dcakd protein networkhttps://string-db.org/network/10090.ENSMUSP00000021313Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family.
Nmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021314Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis.
Efcab15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021323EF-hand calcium-binding domain 15.
Map3k14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021324Mitogen-activated protein kinase kinase kinase 14; Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promo [...]
Lyzl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021328Lysozyme-like protein 6; May be involved sperm-egg plasma membrane adhesion and fusion during fertilization. Exhibits bacteriolytic activity in vitro against Micrococcus luteus and Staphylococcus [...]
Gosr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021329Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
Fkbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021332Peptidyl-prolyl cis-trans isomerase FKBP3; FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arre [...]
Scfd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021335Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endopla [...]
Ap4s1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021338AP-4 complex subunit sigma-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They [...]
Dtd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021339D-aminoacyl-tRNA deacylase 2; Deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Probably acts by rejecti [...]
Gtf2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021345Transcription initiation factor IIA alpha chain; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a com [...]
Tshr protein networkhttps://string-db.org/network/10090.ENSMUSP00000021346Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The act [...]
Sel1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000021347Protein sel-1 homolog 1; Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfol [...]
Dnaaf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021356Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in t [...]
Pole2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021359DNA polymerase epsilon subunit 2; Accessory component of the DNA polymerase epsilon complex (By similarity). Participates in DNA repair and in chromosomal DNA replication (By similarity).
Klhdc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021362Kelch domain-containing protein 2; Represses CREB3-mediated transcription by interfering with CREB3-DNA binding.
Nemf protein networkhttps://string-db.org/network/10090.ENSMUSP00000021368Nuclear export mediator factor Nemf; Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized [...]
L2hgdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000021370L-2-hydroxyglutarate dehydrogenase, mitochondrial.
Sec23a protein networkhttps://string-db.org/network/10090.ENSMUSP00000021375Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main fu [...]
Cdkl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021377Cyclin-dependent kinase-like 1; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Gemin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021379Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important r [...]
Trappc6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000021380Trafficking protein particle complex subunit 6B; Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic (By similarity). Specifi [...]
Pnn protein networkhttps://string-db.org/network/10090.ENSMUSP00000021381Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription [...]
Galc protein networkhttps://string-db.org/network/10090.ENSMUSP00000021390Galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible [...]
Polr2h protein networkhttps://string-db.org/network/10090.ENSMUSP00000021405DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Com [...]
2700097O09Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000021406RIKEN cDNA 2700097O09 gene.
Ppp2r3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000021410Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma; May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 express [...]
Prorp protein networkhttps://string-db.org/network/10090.ENSMUSP00000021411Mitochondrial ribonuclease P catalytic subunit; Catalytic ribonuclease component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP, which cleaves tRNA [...]
Psma6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021412Proteasome subunit alpha type-6; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles w [...]
Nfkbia protein networkhttps://string-db.org/network/10090.ENSMUSP00000021413NF-kappa-B inhibitor alpha; Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular st [...]
Mbip protein networkhttps://string-db.org/network/10090.ENSMUSP00000021416MAP3K12-binding inhibitory protein 1; Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activ [...]
Sptlc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021424Serine palmitoyltransferase 2; Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) [...]
Ahsa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021425Activator of 90 kDa heat shock protein ATPase homolog 1; Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with [...]
Snw1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021428SNW domain-containing protein 1; Involved in pre-mRNA splicing as component of the spliceosome. Is required in the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruit [...]
Nova1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021438RNA-binding protein Nova-1; Functions to regulate alternative splicing in neurons by binding pre-mRNA in a sequence-specific manner to activate exon inclusion. It binds specifically to the sequen [...]
Mthfd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021443C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed; In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Ppp2r5e protein networkhttps://string-db.org/network/10090.ENSMUSP00000021447Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the [...]
Sgpp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021450Sphingosine-1-phosphate phosphatase 1; Specifically dephosphorylates sphingosine 1-phosphate (S1P), dihydro-S1P, and phyto-S1P. Does not act on ceramide 1-phosphate, lysophosphatidic acid or phos [...]
Tex21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021453Testis-expressed gene 21.
Sptb protein networkhttps://string-db.org/network/10090.ENSMUSP00000021458Spectrin beta chain, erythrocytic; Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cyto [...]
Rab15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021459Ras-related protein Rab-15; May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal. EHBP1L1.
Atl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021466Atlastin-1; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular netw [...]
Sav1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021467Protein salvador homolog 1; Regulator of STK3/MST2 and STK4/MST1 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation [...]
Tmx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021471Thioredoxin-related transmembrane protein 1; May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide [...]
Actr10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021479Actin-related protein 10; Belongs to the actin family.
Tomm20l protein networkhttps://string-db.org/network/10090.ENSMUSP00000021482TOMM20-like protein 1.
Serpina1f protein networkhttps://string-db.org/network/10090.ENSMUSP00000021490Alpha-1-antitrypsin 1-6; Inhibitor of serine proteases. Belongs to the serpin family.
Ccdc175 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021494Coiled-coil domain-containing protein 175.
Serpina5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021495Plasma serine protease inhibitor; Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation [...]
Serpina3n protein networkhttps://string-db.org/network/10090.ENSMUSP00000021506Serine protease inhibitor A3N.
Dhrs7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021512Dehydrogenase/reductase SDR family member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Gsc protein networkhttps://string-db.org/network/10090.ENSMUSP00000021513Homeobox protein goosecoid; Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis (By similarity). In conce [...]
Ppm1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000021514Protein phosphatase 1A; Enzyme with a broad specificity. Negatively regulates TGF- beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear ex [...]
Six6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021519Homeobox protein SIX6; May be involved in eye development.
Glrx5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021522Glutaredoxin-related protein 5, mitochondrial; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters (By similarity). Involved in protein lipoylation, acting in the pathway t [...]
Mnat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021523CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CD [...]
Prkch protein networkhttps://string-db.org/network/10090.ENSMUSP00000021527Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in ker [...]
Hif1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000021530Hypoxia-inducible factor 1-alpha; Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, incl [...]
Snapc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021532snRNA-activating protein complex subunit 1; Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence elem [...]
Atp6v1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000021536V-type proton ATPase subunit D; Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, [...]
Plek2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021544Pleckstrin-2; May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation. Overexpression of pleckstrin 2 causes large lamellipodia and peripheral ruffle formation.
Zfyve26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021547Zinc finger FYVE domain-containing protein 26; Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and act [...]
Rdh12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021548Retinol dehydrogenase 12; Retinoids dehydrogenase/reductase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans- retinal. Shows very weak activity toward [...]
Arg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021550Arginase-2, mitochondrial; May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regu [...]
Zfp36l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021552mRNA decay activator protein ZFP36L1; Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail remov [...]
Actn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021554Alpha-actinin-1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity).
Pcnx protein networkhttps://string-db.org/network/10090.ENSMUSP00000021567Pecanex-like protein 1; Belongs to the pecanex family.
Cdca7l protein networkhttps://string-db.org/network/10090.ENSMUSP00000021592Cell division cycle-associated 7-like protein; Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the pr [...]
Psmc1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002159526S proteasome regulatory subunit 4; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in [...]
Nrde2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021596Nuclear exosome regulator NRDE2; Protein of the nuclear speckles that regulates RNA degradation and export from the nucleus through its interaction with MTREX an essential factor directing variou [...]
Fbln5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021603Fibulin-5; Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (By similarity). Stabilizes [...]
Trip11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021605Thyroid hormone receptor interactor 11.
Atxn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021606Ataxin-3; Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates (By similarity) [...]
Lgmn protein networkhttps://string-db.org/network/10090.ENSMUSP00000021607Legumain; Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. May be involved in the processing of proteins fo [...]
Golga5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021609Golgin subfamily A member 5; Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport (By similarity).
Chga protein networkhttps://string-db.org/network/10090.ENSMUSP00000021610p-Glu serpinin precursor; [Pancreastatin]: Strongly inhibits glucose induced insulin release from the pancreas. [Serpinin]: Regulates granule biogenesis in endocrine cells by up-regulating the tr [...]
Asb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021617Ankyrin repeat and SOCS box protein 2; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquiti [...]
Akr1c21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021628Aldo-keto reductase family 1 member C21; NADP-dependent 17-alpha-hydroxysteroid dehydrogenase that converts 5-alpha-androstane-3,17-dione into androsterone. Has lower 3- alpha-hydroxysteroid dehy [...]
Akr1c6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021630Estradiol 17 beta-dehydrogenase 5; Active toward androgens, estrogens, and xenobiotic substrates. Also exhibits low 20 alpha-HSD activity. Shows a- stereospecificity in hydrogen transfer between [...]
Ppp4r4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021631Serine/threonine-protein phosphatase 4 regulatory subunit 4; Putative regulatory subunit of serine/threonine-protein phosphatase 4.
Akr1c12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021632Aldo-keto reductase family 1, member C12.
Akr1c13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021634Aldo-keto reductase family 1 member C13; Catalyzes the dehydrogenation of 17-beta-hydroxysteroids. May also exhibit significant activity with a variety of cyclic and alicyclic alcohols. Uses both [...]
Akr1c18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021635Aldo-keto reductase family 1 member C18; Catalyzes the conversion of progesterone into 20-alpha- dihydroprogesterone (20 alpha-OHP); Belongs to the aldo/keto reductase family.
Tubal3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021639Tubulin alpha chain-like 3; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the al [...]
Tshz3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021641Teashirt homolog 3; Transcriptional regulator involved in developmental processes. Functions in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expr [...]
Dcaf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021645DDB1 and CUL4-associated factor 4.
Acot2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021649Acyl-coenzyme A thioesterase 2, mitochondrial; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the [...]
Acot4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021652Peroxisomal succinyl-coenzyme A thioesterase; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the [...]
Acot3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021653Acyl-coenzyme A thioesterase 3; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to r [...]
Fam161b protein networkhttps://string-db.org/network/10090.ENSMUSP00000021659Protein FAM161B; Belongs to the FAM161 family.
Abcd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021666ATP-binding cassette sub-family D member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm (B [...]
Isca2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021667Iron-sulfur cluster assembly 2 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in [...]
Npc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021668NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal comp [...]
Fcf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021669rRNA-processing protein FCF1 homolog; Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly; Belongs to the UTP23/FCF1 family. FCF1 subfamily.
Ylpm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021670YLP motif-containing protein 1.
Fos protein networkhttps://string-db.org/network/10090.ENSMUSP00000021674Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/J [...]
Erg28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021676Ergosterol biosynthetic protein 28 homolog.
Vash1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021681Tubulinyl-Tyr carboxypeptidase 1; Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Acts as an angioge [...]
Angel1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021682Protein angel homolog 1; Belongs to the CCR4/nocturin family.
Cyp46a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021684Cholesterol 24-hydroxylase; P450 monooxygenase that plays a major role in cholesterol homeostasis in the brain. Primarily catalyzes the hydroxylation (with S stereochemistry) at C-24 of cholester [...]
Hhipl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021685HHIP-like protein 1; Belongs to the HHIP family.
Evl protein networkhttps://string-db.org/network/10090.ENSMUSP00000021689Ena/VASP-like protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipod [...]
Degs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021691Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2; Bifunctional enzyme which acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-monooxygenase. Belongs to the fatty acid de [...]
Yy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021692Transcriptional repressor protein YY1; Multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlappi [...]
Slc25a29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021693Mitochondrial basic amino acids transporter; Transports arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine. Does not transport carnitine nor acyl [...]
Traf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021706TNF receptor-associated factor 3; Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling path [...]
Amn protein networkhttps://string-db.org/network/10090.ENSMUSP00000021707Soluble protein amnionless; Membrane-bound component of the endocytic receptor formed by AMN and CUBN. Required for normal CUBN glycosylation and trafficking to the cell surface. The complex form [...]
Zfyve21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021714Zinc finger FYVE domain-containing protein 21; Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtub [...]
Xrcc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021715DNA repair protein XRCC3; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of [...]
Adssl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021726Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes [...]
Siva1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021728Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-media [...]
Gpr132 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021729Probable G-protein coupled receptor 132; May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9-hydroxyoctadecadienoic acid (9-HODE). Activates a G [...]
Gng4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021734Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling sy [...]
Gpr137b protein networkhttps://string-db.org/network/10090.ENSMUSP00000021738Integral membrane protein GPR137B; Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth fact [...]
Ryr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021750Ryanodine receptor 2; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. [...]
Aoah protein networkhttps://string-db.org/network/10090.ENSMUSP00000021757Acyloxyacyl hydrolase large subunit; Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides (LPS). By breaking down LPS, terminates [...]
Slc17a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021769Probable small intestine urate exporter; Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate ex [...]
Scgn protein networkhttps://string-db.org/network/10090.ENSMUSP00000021770Secretagogin.
Mrs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021772Magnesium transporter MRS2 homolog, mitochondrial; Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix. Required for normal expression of the mitochondrial r [...]
Gpld1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021773Phosphatidylinositol-glycan-specific phospholipase D; This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these [...]
Prl4a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021779Prolactin-4A1.
Irf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021784Interferon regulatory factor 4; Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enha [...]
Tmem14c protein networkhttps://string-db.org/network/10090.ENSMUSP00000021790Transmembrane protein 14C; Required for normal heme biosynthesis; Belongs to the TMEM14 family.
Gcm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021791Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, ma [...]
Elovl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021793Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endopla [...]
Nedd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021794Enhancer of filamentation 1; Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control sign [...]
Edn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021796Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 [...]
Mcur1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021800Mitochondrial calcium uniporter regulator 1; Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion. Plays a direct role in uniporter-mediated calciu [...]
Cap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021802Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family.
Nup153 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021803Nucleoporin 153.
Tpmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000021806Thiopurine S-methyltransferase; Catalyzes the S-methylation of thiopurine drugs such as 6- mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) using S-adenosyl-L-methio [...]
Dek protein networkhttps://string-db.org/network/10090.ENSMUSP00000021807Protein DEK; Involved in chromatin organization.
Id4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021810DNA-binding protein inhibitor ID-4; Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming he [...]
Barx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021813Homeobox protein BarH-like 1; Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars [...]
Cenpp protein networkhttps://string-db.org/network/10090.ENSMUSP00000021818Centromere protein P; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chr [...]
Ogn protein networkhttps://string-db.org/network/10090.ENSMUSP00000021822Mimecan; Induces bone formation in conjunction with TGF-beta-1 or TGF- beta-2; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
Nxnl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021828Nucleoredoxin-like protein 2; May be involved in the maintenance of both the function and the viability of sensory neurons, including photoreceptors and olfactory neurons. In the retina, isoform [...]
Wrnip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021832ATPase WRNIP1; Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediat [...]
Serpinb1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000021834Leukocyte elastase inhibitor C; Regulates the activity of the neutrophil proteases. Forms only a stable complex with CTSG/Cathepsin G (By similarity). During inflammation, limits the activity of [...]
Serpinb9c protein networkhttps://string-db.org/network/10090.ENSMUSP00000021837Serine (or cysteine) peptidase inhibitor, clade B, member 9c; Belongs to the serpin family.
Fam217a protein networkhttps://string-db.org/network/10090.ENSMUSP00000021851Protein FAM217A; Belongs to the FAM217 family.
Eci3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021853Enoyl-CoA delta isomerase 3, peroxisomal; Catalyzes the isomerization of trans-3-nonenoyl-CoA into trans-2-nonenoyl-CoA. May also have activity towards other enoyl-CoA species (Probable).
Fars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021857Phenylalanine--tRNA ligase, mitochondrial; Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m- [...]
Ly86 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021860Lymphocyte antigen 86; May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell su [...]
Ssr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021864Translocon-associated protein subunit alpha; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. M [...]
Riok1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021866Serine/threonine-protein kinase RIO1; Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required [...]
Slc35b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021870Adenosine 3'-phospho 5'-phosphosulfate transporter 2; Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sul [...]
Ctla2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000021880Protein CTLA-2-alpha; Not known, expressed in activated T-cell; To the propeptide regions of cysteine proteases.
Ctla2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000021884Protein CTLA-2-beta; Not known, expressed in activated T-cell.
Tpbpa protein networkhttps://string-db.org/network/10090.ENSMUSP00000021885Trophoblast-specific protein alpha; It may be a growth factor/hormone, perhaps involved in interaction between the maternal and fetal systems in maintenance of pregnancy.
Ctsq protein networkhttps://string-db.org/network/10090.ENSMUSP00000021888Cathepsin Q; Belongs to the peptidase C1 family.
Ctsr protein networkhttps://string-db.org/network/10090.ENSMUSP00000021889Cathepsin R.
Cts6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021890Cathepsin-6; Belongs to the peptidase C1 family.
Cts8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021891Cathepsin 8; Probable protease (By similarity). In placenta, plays a role in promoting giant cell differentiation. Also plays a role in placental spiral artery remodeling by direct degradation of [...]
Cts7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021892Cathepsin 7; Involved in trophoblast cell proliferation and differentiation probably by affecting mitotic cell cycle progression. Proteolytic activity and nuclear localization are essential for i [...]
Shc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021898SHC-transforming protein 3; Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activate [...]
Sema4d protein networkhttps://string-db.org/network/10090.ENSMUSP00000021900Semaphorin-4D; Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (By similarity). Regulates GABAergic synapse development. Promotes the development o [...]
Gadd45g protein networkhttps://string-db.org/network/10090.ENSMUSP00000021903Growth arrest and DNA damage-inducible protein GADD45 gamma; Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK; Belongs to the GADD45 [...]
Fbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021907Fructose-1,6-bisphosphatase isozyme 2; Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synt [...]
Auh protein networkhttps://string-db.org/network/10090.ENSMUSP00000021913Methylglutaconyl-CoA hydratase, mitochondrial; Catalyzes the conversion of 3-methylglutaconyl-CoA to 3- hydroxy-3-methylglutaryl-CoA (By similarity). Also has itaconyl-CoA hydratase activity by c [...]
Ror2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021918Tyrosine-protein kinase transmembrane receptor ROR2; Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and g [...]
Sptlc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021920Serine palmitoyltransferase 1; Serine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase ( [...]
Ptch1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021921Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's p [...]
Msx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021922Homeobox protein MSX-2; Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during oste [...]
Habp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021929Intracellular hyaluronan-binding protein 4; RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation. Negatively regulates DNA-binding acti [...]
Sfxn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021930Sideroflexin-1; Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (By similarity). Mitochondrial serine [...]
Drd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021932D(1A) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Zfp346 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021937Zinc finger protein 346; Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity (By similarity). May bind to specific miRNA hairpins [...]
Cdk20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021939Cyclin-dependent kinase 20; Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (By similarity). Required for high-le [...]
Lman2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021940Vesicular integral-membrane protein VIP36; Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high- mannose type glycans and may a [...]
Mxd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021941Max dimerization protein 3; Transcriptional repressor. Binds with MAX to form a sequence- specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC [...]
Prelid1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021942PRELI domain-containing protein 1, mitochondrial; Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In [...]
F12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021948Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. P [...]
Dbn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021950Drebrin; Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (By similarity). Required for actin polymerization at immunological synapses (IS) and for the [...]
Ddx41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021956Probable ATP-dependent RNA helicase DDX41; Probable ATP-dependent RNA helicase. Is required during post- transcriptional gene expression. May be involved in pre-mRNA splicing.
Fam193b protein networkhttps://string-db.org/network/10090.ENSMUSP00000021957Protein FAM193B; Belongs to the FAM193 family.
Pcbd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021958Pterin-4-alpha-carbinolamine dehydratase 2; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 (By simila [...]
Txndc15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021959Thioredoxin domain-containing protein 15; Acts as a positive regulator of ciliary hedgehog signaling. Required for cilia biogenesis.
Catsper3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021961Cation channel sperm-associated protein 3; Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a [...]
Caml protein networkhttps://string-db.org/network/10090.ENSMUSP00000021963Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.
Pitx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021968Pituitary homeobox 1; Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particu [...]
Cxcl14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021970C-X-C motif chemokine 14; Chemotactic for CESS B-cells and THP-1 monocytes, but not T- cells.
Slc25a48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021971Solute carrier family 25 member 48.
Ptdss1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021990Phosphatidylserine synthase 1; Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, [...]
Mterf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021991Transcription termination factor 3, mitochondrial; Binds promoter DNA and regulates initiation of transcription (By similarity). Required for normal mitochondrial transcription and translation, a [...]
Uqcrb protein networkhttps://string-db.org/network/10090.ENSMUSP00000021993Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which dr [...]
Rsl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000021997Regulator of sex limited protein 1.
1700001L19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000022007Uncharacterized protein C5orf49 homolog.
Cetn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022009Centrin-3; Plays a fundamental role in microtubule-organizing center structure and function; Belongs to the centrin family.
Adcy2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022013Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Down-stream signaling cascades mediate changes in gene expression patterns and [...]
Il9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022019Interleukin-9; Supports IL-2 independent and IL-4 independent growth of helper T-cells; Belongs to the IL-7/IL-9 family.
Trpc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022023Short transient receptor potential channel 7; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger s [...]
Ccnh protein networkhttps://string-db.org/network/10090.ENSMUSP00000022030Cyclin-H; Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphoryl [...]
2210016F16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000022032Queuosine salvage protein; Involved in salvaging queuosine.
Slc28a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022036Solute carrier family 28 member 3; Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleos [...]
Naa35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022038N-alpha-acetyltransferase 35, NatC auxiliary subunit; Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Invol [...]
Golm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022039Golgi membrane protein 1; Unknown. Cellular response protein to viral infection (By similarity).
Agtpbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022040Cytosolic carboxypeptidase 1; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational [...]
Slc6a19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022048Sodium-dependent neutral amino acid transporter B(0)AT1; Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells. This upta [...]
Nkd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022051Protein naked cuticle homolog 2; Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for pr [...]
Trip13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022053Pachytene checkpoint protein 2 homolog; Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that lea [...]
Tppp protein networkhttps://string-db.org/network/10090.ENSMUSP00000022057Tubulin polymerization-promoting protein; Regulator of microtubule dynamics that plays a key role in myelination by promoting elongation of the myelin sheath. Acts as a microtubule nucleation fac [...]
Ahrr protein networkhttps://string-db.org/network/10090.ENSMUSP00000022059Aryl hydrocarbon receptor repressor; Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this [...]
Pdcd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022060Programmed cell death protein 6; Calcium sensor that plays a key role in processes such as endoplasmic reticulum (ER)-Golgi vesicular transport, endosomal biogenesis or membrane repair. Acts as a [...]
Sdha protein networkhttps://string-db.org/network/10090.ENSMUSP00000022062Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron t [...]
Ccdc127 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022063Coiled-coil domain-containing protein 127.
Lrrc14b protein networkhttps://string-db.org/network/10090.ENSMUSP00000022064Leucine-rich repeat-containing protein 14B; Belongs to the PRAME family. LRRC14 subfamily.
Pcsk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022075Neuroendocrine convertase 1; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephali [...]
Rhobtb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022078Rho-related BTB domain-containing protein 3; Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating [...]
Spata9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022081Spermatogenesis-associated protein 9; May play at role in testicular development/spermatogenesis and may be an important factor in male infertility.
Glrx protein networkhttps://string-db.org/network/10090.ENSMUSP00000022082Glutaredoxin-1; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins; Belongs to the glutar [...]
Med10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022089Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Irx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022095Iroquois-class homeodomain protein IRX-4; Likely to be an important mediator of ventricular differentiation during cardiac development; Belongs to the TALE/IRO homeobox family.
Ndufs6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022097NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be [...]
Mrpl36 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002209839S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family.
Lpcat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022099Lysophosphatidylcholine acyltransferase 1; Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-independent. Mediates the conversion of 1-acyl-sn-glycero-3- phosph [...]
Slc6a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022100Sodium-dependent dopamine transporter; Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. Belongs to the sodium:neurot [...]
Clptm1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000022102Cleft lip and palate transmembrane protein 1-like protein; Enhances cisplatin-mediated apoptosis, when overexpressed. Belongs to the CLPTM1 family.
Tert protein networkhttps://string-db.org/network/10090.ENSMUSP00000022104Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, [...]
Hapln1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022108Hyaluronan and proteoglycan link protein 1; Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.
Xrcc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022115DNA repair protein XRCC4; Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC [...]
Atg10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022119Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for [...]
Acot12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022120Acetyl-coenzyme A thioesterase; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to r [...]
Zcchc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022121Zinc finger CCHC domain-containing protein 9; May down-regulate transcription mediated by NF-kappa-B and the serum response element.
Ckmt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022122Creatine kinase S-type, mitochondrial; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role [...]
Cd180 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022124CD180 antigen; May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF- kappa-B activation. Also involved in the life/ [...]
Rad17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022136Cell cycle checkpoint protein RAD17; Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity [...]
Naip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022142Baculoviral IAP repeat-containing protein 1a; Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of p [...]
Serf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022145Small EDRK-rich factor 1; Positive regulator of amyloid protein aggregation and proteotoxicity (By similarity). Induces conformational changes in amyloid proteins, such as APP, HTT, and SNCA, dri [...]
Smn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022147Survival motor neuron protein; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an import [...]
Mccc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022148Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to [...]
Cartpt protein networkhttps://string-db.org/network/10090.ENSMUSP00000022150Cocaine- and amphetamine-regulated transcript protein; Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation- [...]
Ptcd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022153Pentatricopeptide repeat-containing protein 2, mitochondrial; Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function; Belongs to the PTCD2 family.
Btf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022163Transcription factor BTF3; When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they [...]
Ankra2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022164Ankyrin repeat family A protein 2; May regulate the interaction between the 3M complex and the histone deacetylases HDAC4 and HDAC5 (By similarity). May also regulate LRP2/megalin.
Hexb protein networkhttps://string-db.org/network/10090.ENSMUSP00000022169Beta-hexosaminidase subunit beta; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.
Polk protein networkhttps://string-db.org/network/10090.ENSMUSP00000022172DNA polymerase kappa; DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA s [...]
Hmgcr protein networkhttps://string-db.org/network/10090.ENSMUSP000000221763-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids th [...]
F2rl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022182Proteinase-activated receptor 3; High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation; Belongs t [...]
F2rl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022185Proteinase-activated receptor 2; Receptor for trypsin and trypsin-like enzymes coupled to G proteins. Its function is mediated through the activation of several signaling pathways including phosp [...]
S100z protein networkhttps://string-db.org/network/10090.ENSMUSP00000022186Protein S100; Belongs to the S-100 family.
Aggf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022189Angiogenic factor with G patch and FHA domains 1; Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting th [...]
Otp protein networkhttps://string-db.org/network/10090.ENSMUSP00000022195Homeobox protein orthopedia; Involved in the specification of hypothalamic neuroendocrine cells. Specifically required for the specification of diencephalic dopaminergic neurons of the A11 group.
Ap3b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022196AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and [...]
Scamp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022197Secretory carrier-associated membrane protein 1; Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface (By similarity).
Dimt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022203Probable dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. Involved in the pre-r [...]
Elovl7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022207Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endopla [...]
Plk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022212Serine/threonine-protein kinase PLK2; Tumor suppressor serine/threonine-protein kinase involved in synaptic plasticity, centriole duplication and G1/S phase transition. Polo-like kinases act by b [...]
Thbs4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022213Thrombospondin-4; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and [...]
Zfyve16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022217Zinc finger FYVE domain-containing protein 16; May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to [...]
Dhfr protein networkhttps://string-db.org/network/10090.ENSMUSP00000022218Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine [...]
Trappc13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022224Trafficking protein particle complex subunit 13; Belongs to the TRAPPC13 family.
Ppwd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022226Peptidylprolyl isomerase domain and WD repeat-containing protein 1; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist pro [...]
Cenpk protein networkhttps://string-db.org/network/10090.ENSMUSP00000022227Centromere protein K; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chr [...]
Cwc27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022228Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity; Belongs [...]
Srek1ip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022230Protein SREK1IP1; Possible splicing regulator involved in the control of cellular survival.
Nt5el protein networkhttps://string-db.org/network/10090.ENSMUSP000000222325' nucleotidase, ecto-like; Belongs to the 5'-nucleotidase family.
Htr1a protein networkhttps://string-db.org/network/10090.ENSMUSP000000222355-hydroxytryptamine receptor 1A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes [...]
Parp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022239Protein mono-ADP-ribosyltransferase PARP8; Mono-ADP-ribosyltransferase that mediates mono-ADP- ribosylation of target proteins.
Emb protein networkhttps://string-db.org/network/10090.ENSMUSP00000022242Embigin; Plays a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane (By similarity). Plays a role in the outgrowth of motoneurons and in the formation of [...]
Mrps30 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002224528S ribosomal protein S30, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL65 family.
Fgf10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022246Fibroblast growth factor 10; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play [...]
Psmd6 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002225626S proteasome non-ATPase regulatory subunit 6; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a k [...]
Atxn7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022257Ataxin-7; Involved in neurodegeneration. Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-depend [...]
Ptprg protein networkhttps://string-db.org/network/10090.ENSMUSP00000022264Receptor-type tyrosine-protein phosphatase gamma; Possesses tyrosine phosphatase activity.
Pdhb protein networkhttps://string-db.org/network/10090.ENSMUSP00000022268Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the gly [...]
Oit1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022269Protein FAM3D.
Ankrd55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022275Ankyrin repeat domain-containing protein 55.
Mtrex protein networkhttps://string-db.org/network/10090.ENSMUSP00000022281Exosome RNA helicase MTR4; Catalyzes the ATP-dependent unwinding of RNA duplexes with a single-stranded 3' RNA extension. Central subunit of many protein complexes, namely TRAMP-like, nuclear exo [...]
Gpx8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022282Probable glutathione peroxidase 8; Belongs to the glutathione peroxidase family.
Ndufs4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022286NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be [...]
Samd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022292Sphingomyelin synthase-related protein 1; sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endopl [...]
Vdac2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022293Voltage-dependent anion-selective channel protein 2; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conf [...]
Ube2e1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022296Ubiquitin-conjugating enzyme E2 E1; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Me [...]
Thrb protein networkhttps://string-db.org/network/10090.ENSMUSP00000022304Thyroid hormone receptor beta; Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyr [...]
Ngly1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022310Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degrad [...]
Oxsm protein networkhttps://string-db.org/network/10090.ENSMUSP000000223113-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
Dydc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022316DPY30 domain-containing 2.
Glud1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022322Glutamate dehydrogenase 1, mitochondrial; Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-k [...]
Ldb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022327LIM domain-binding protein 3; May function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton.
Opn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022331Melanopsin; Photoreceptor required for regulation of circadian rhythm. Contributes to pupillar reflex and other non-image forming responses to light. May be able to isomerize covalently bound all [...]
Cdhr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022337Cadherin-related family member 1; Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer segment (OS) of photoreceptor cells.
Rgr protein networkhttps://string-db.org/network/10090.ENSMUSP00000022338RPE-retinal G protein-coupled receptor; Receptor for all-trans- and 11-cis-retinal. Binds preferentially to the former and may catalyze the isomerization of the chromophore by a retinochrome-like [...]
Nid2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022340Nidogen-2; Cell adhesion glycoprotein. Might be involved in osteoblast differentiation. It probably has a role in cell-extracellular matrix interactions.
Rtraf protein networkhttps://string-db.org/network/10090.ENSMUSP00000022341RNA transcription, translation and transport factor protein; RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. Component of the tRNA-splicing ligase complex and i [...]
Nudt13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022343Nucleoside diphosphate-linked moiety X motif 13.
Ecd protein networkhttps://string-db.org/network/10090.ENSMUSP00000022344Protein ecdysoneless homolog; Regulator of p53/TP53 stability and function. Inhibits MDM2- mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcripti [...]
Dnajc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022345DnaJ homolog subfamily C member 9; May play a role as co-chaperone of the Hsp70 family proteins HSPA1A, HSPA1B and HSPA8.
Mss51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022353Putative protein MSS51 homolog, mitochondrial.
Usp54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022356Inactive ubiquitin carboxyl-terminal hydrolase 54; Has no peptidase activity; Belongs to the peptidase C19 family.
Zswim8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022358Zinc finger SWIM domain-containing protein 8.
Plau protein networkhttps://string-db.org/network/10090.ENSMUSP00000022368Urokinase-type plasminogen activator short chain A; Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin; Belongs to the peptidase S1 family.
Vcl protein networkhttps://string-db.org/network/10090.ENSMUSP00000022369Vinculin; Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E- [...]
Ero1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000022378ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in o [...]
Psmc6 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002238026S proteasome regulatory subunit 10B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role i [...]
Samd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022386Protein Smaug homolog 1; Acts as a translational repressor of SRE-containing messengers; Belongs to the SMAUG family.
Anxa11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022416Annexin A11; Required for midbody formation and completion of the terminal phase of cytokinesis (By similarity). Binds specifically to calcyclin in a calcium-dependent manner; Belongs to the anne [...]
Ppif protein networkhttps://string-db.org/network/10090.ENSMUSP00000022419Peptidyl-prolyl cis-trans isomerase F, mitochondrial; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. [...]
Rnase10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022424Inactive ribonuclease-like protein 10; Secreted proximal epididymal protein required for post- testicular sperm maturation and male fertility. May be involved in sperm adhesion to the egg zona pe [...]
Rnase4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022428Ribonuclease 4; This RNase has marked specificity towards the 3' side of uridine nucleotides; Belongs to the pancreatic ribonuclease family.
Arf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022429ADP-ribosylation factor 4; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may mo [...]
Dnah12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022433Dynein heavy chain 12, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke [...]
Hacl1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000224372-hydroxyacyl-CoA lyase 1; Catalyzes a carbon-carbon cleavage reaction; cleaves a 2- hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.
Vmn2r88 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022438Vomeronasal 2, receptor 88.
Eaf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022446ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities.
Tasor protein networkhttps://string-db.org/network/10090.ENSMUSP00000022450Protein TASOR; Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is required to maintain [...]
Capn7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022451Calpain-7; Calcium-regulated non-lysosomal thiol-protease.
Bap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022458Ubiquitin carboxyl-terminal hydrolase BAP1; Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB co [...]
Phf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022459PHD finger protein 7; May play a role in spermatogenesis.
Galnt15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022460Polypeptide N-acetylgalactosaminyltransferase 15; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threo [...]
Oxnad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022462Oxidoreductase NAD-binding domain-containing protein 1.
Msmb protein networkhttps://string-db.org/network/10090.ENSMUSP00000022464Beta-microseminoprotein; Belongs to the beta-microseminoprotein family.
Nisch protein networkhttps://string-db.org/network/10090.ENSMUSP00000022469Nischarin; Acts either as the functional imidazoline-1 receptor (I1R) candidate or as a membrane-associated mediator of the I1R signaling. Binds numerous imidazoline ligands that induces initiati [...]
Parg protein networkhttps://string-db.org/network/10090.ENSMUSP00000022470Poly(ADP-ribose) glycohydrolase; Poly(ADP-ribose) glycohydrolase that degrades poly(ADP- ribose) by hydrolyzing the ribose-ribose bonds present in poly(ADP- ribose). PARG acts both as an endo- an [...]
Glt8d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022476Glycosyltransferase 8 domain-containing protein 1; Belongs to the glycosyltransferase 8 family.
Ogdhl protein networkhttps://string-db.org/network/10090.ENSMUSP00000022480Oxoglutarate dehydrogenase-like.
Ebpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000022494Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands.
Kpna3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022496Importin subunit alpha-4; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or biparti [...]
Spryd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022497SPRY domain-containing protein 7.
Rnaseh2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000022499Ribonuclease H2 subunit B; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the rem [...]
Gucy1b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022501Guanylate cyclase 1, soluble, beta 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Mapk8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022504Mitogen-activated protein kinase.
Pspc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022507Paraspeckle component 1; Together with NONO, required for the formation of nuclear paraspeckles. Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activit [...]
Ptpn20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022508Tyrosine-protein phosphatase non-receptor type 20; Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase act [...]
Zmym2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022511Zinc finger MYM-type protein 2; May function as a transcription factor.
Cryl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022517Lambda-crystallin homolog; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Eef1akmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022518EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase su [...]
Anxa8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022519Annexin A8; This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade; Belongs to the [...]
Tdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000022522L-threonine 3-dehydrogenase, mitochondrial; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate, mediating L-threonine catabolism. Belongs to the NAD(P)-dependent e [...]
Pinx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022528PIN2/TERF1-interacting telomerase inhibitor 1; Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 bindin [...]
Tkt protein networkhttps://string-db.org/network/10090.ENSMUSP00000022529Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
Lats2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022531Serine/threonine-protein kinase LATS2; Negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation [...]
4930578I06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000022532Uncharacterized protein C8orf74 homolog.
Dcp1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000022535mRNA-decapping enzyme 1A; Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, [...]
Ska3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022536Spindle and kinetochore-associated protein 3; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA [...]
Prss52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022537Serine protease 52; Probable serine protease; Belongs to the peptidase S1 family.
Mrpl57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022538Ribosomal protein 63, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL63 family.
Micu2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022543Calcium uptake protein 2, mitochondrial; Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a dis [...]
Fgf9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022545Fibroblast growth factor 9; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth a [...]
Rcbtb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022551RCC1 and BTB domain-containing protein 1; May be involved in cell cycle regulation by chromatin remodeling.
Cab39l protein networkhttps://string-db.org/network/10090.ENSMUSP00000022553Calcium-binding protein 39-like; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO [...]
Mtmr6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022563Myotubularin-related protein 6; Phosphatase that acts on lipids with a phosphoinositol headgroup. Dephosphorylates phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,5-bisph [...]
Spata13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022566Spermatogenesis-associated protein 13; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a [...]
Cacna2d3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022567Voltage-dependent calcium channel subunit alpha-2/delta-3; The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics o [...]
Lrrc63 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022574Leucine-rich repeat-containing protein 63.
Cpb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022576Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down [...]
Zc3h13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022577Zinc finger CCCH domain-containing protein 13; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in t [...]
Erich6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000022579Glutamate-rich 6B.
Slc25a30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022580Kidney mitochondrial carrier protein 1; Probable transporter.
Gpalpp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022585GPALPP motifs-containing protein 1.
Nufip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022586Nuclear fragile X mental retardation-interacting protein 1; Binds RNA.
Enox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022589Protein disulfide-thiol oxidoreductase; Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone ox [...]
Epsti1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022591Epithelial-stromal interaction protein 1; Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation. M [...]
Tnfsf11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022592Tumor necrosis factor ligand superfamily member 11, membrane form; Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the abili [...]
Akap11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022593A kinase (PRKA) anchor protein 11.
Rgcc protein networkhttps://string-db.org/network/10090.ENSMUSP00000022595Regulator of cell cycle RGCC; Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells [...]
Naa16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022597N-alpha-acetyltransferase 16, NatA auxiliary subunit; Auxillary subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity.
Mtrf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022600Peptide chain release factor 1, mitochondrial; Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain non-cognate termination stop [...]
Wbp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022601WW domain-binding protein 4; Involved in pre-mRNA splicing as a component of the spliceosome. May play a role in cross-intron bridging of U1 and U2 snRNPs in the mammalian A complex.
Elp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022609Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved [...]
Scara5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022610Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosi [...]
Pbk protein networkhttps://string-db.org/network/10090.ENSMUSP00000022612Lymphokine-activated killer T-cell-originated protein kinase; Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When pho [...]
Esco2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022613N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromati [...]
Ccdc25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022614Coiled-coil domain-containing protein 25; Belongs to the CCDC25 family.
Clu protein networkhttps://string-db.org/network/10090.ENSMUSP00000022616Clusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins (By similarity). Inhibit [...]
Adam2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022618Disintegrin and metalloproteinase domain-containing protein 2; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Could ha [...]
Chrna2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022620Neuronal acetylcholine receptor subunit alpha-2; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-con [...]
Ptk2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000022622Protein-tyrosine kinase 2-beta; Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remod [...]
Trim35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022623Tripartite motif-containing protein 35; Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth (By similarity). [...]
Dpysl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022629Dihydropyrimidinase-related protein 2; Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for s [...]
Bnip3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000022634BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; Induces apoptosis. Interacts with viral and cellular anti- apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, althou [...]
Nefm protein networkhttps://string-db.org/network/10090.ENSMUSP00000022638Neurofilament medium polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
Nefl protein networkhttps://string-db.org/network/10090.ENSMUSP00000022639Neurofilament light polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
Adam7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022640Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metallo [...]
Adamdec1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022641ADAM DEC1; May play an important role in the control of the immune response and during pregnancy.
Adam28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022642Disintegrin and metalloproteinase domain-containing protein 28; May play a role in organogenesis and organ-specific functions such as thymic T-cell development.
Nkx3-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022646Homeobox protein Nkx-3.1; Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor (By similarity). Plays an important [...]
Pibf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022650Progesterone immunomodulatory-binding factor 1.
Bora protein networkhttps://string-db.org/network/10090.ENSMUSP00000022656Protein aurora borealis; Required for the activation of AURKA at the onset of mitosis. Belongs to the BORA family.
Loxl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022660Lysyl oxidase homolog 2; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts [...]
Tnfrsf10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000022663Tumor necrosis factor receptor superfamily member 10B; Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death [...]
Rhobtb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022665Rho-related BTB domain-containing protein 2; Belongs to the small GTPase superfamily. Rho family.
Klhl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022666Kelch-like protein 1; May play a role in organizing the actin cytoskeleton of the brain cells.
Pebp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022678Phosphatidylethanolamine-binding protein 4; Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine e [...]
Bin3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022680Bridging integrator 3; Involved in cytokinesis and septation where it has a role in the localization of F-actin.
Sorbs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022682Vinexin; Promotes up-regulation of actin stress fiber formation.
Fam160b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022690Protein FAM160B2.
Sftpc protein networkhttps://string-db.org/network/10090.ENSMUSP00000022692Pulmonary surfactant-associated protein C; Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air sp [...]
Bmp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022693Bone morphogenetic protein 1; Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early develo [...]
Xpo7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022696Exportin-7; Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. [...]
Fgf17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022697Fibroblast growth factor 17; Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for norm [...]
Dok2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022698Docking protein 2; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate [...]
Gfra2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022699GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosin [...]
Rb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022701Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcripti [...]
Itm2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000022704Integral membrane protein 2B; Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils [...]
Med4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022705Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Me [...]
Gpc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022707Secreted glypican-5; Cell surface proteoglycan that bears heparan sulfate.
Trim52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022708Tripartite motif-containing 52.
Spry2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022709Protein sprouty homolog 2; May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis; Belongs to the sprouty family.
Rnf219 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022716ORC ubiquitin ligase 1; E3 ubiquitin ligase essential for DNA replication origin activation during S phase. Acts as a replication origin selector which selects the origins to be fired and catalyz [...]
Ednrb protein networkhttps://string-db.org/network/10090.ENSMUSP00000022718Endothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger syst [...]
Fbxl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022720F-box/LRR-repeat protein 3; Substrate-recognition component of the SCF(FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the sp [...]
Cln5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022721Ceroid-lipofuscinosis neuronal protein 5 homolog, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the tr [...]
Acod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022722Cis-aconitate decarboxylase; Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimu [...]
Dct protein networkhttps://string-db.org/network/10090.ENSMUSP00000022725L-dopachrome tautomerase; Catalyzes the conversion of L-dopachrome into 5,6- dihydroxyindole-2-carboxylic acid (DHICA). Involved in regulating eumelanin and phaeomelanin levels.
Tgds protein networkhttps://string-db.org/network/10090.ENSMUSP00000022727dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
Gpr180 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022728Integral membrane protein GPR180.
Dnajc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022734DnaJ homolog subfamily C member 3; Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by pr [...]
Gdnf protein networkhttps://string-db.org/network/10090.ENSMUSP00000022744Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptak [...]
Osmr protein networkhttps://string-db.org/network/10090.ENSMUSP00000022746Oncostatin-M-specific receptor subunit beta; Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5 (By similarity). Capable of transducing OS [...]
C9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022749Complement component C9; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. [...]
Ttc33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022751Tetratricopeptide repeat protein 33.
Gzmf protein networkhttps://string-db.org/network/10090.ENSMUSP00000022757Granzyme F; This enzyme is probably necessary for target cell lysis in cell-mediated immune responses; Belongs to the peptidase S1 family. Granzyme subfamily.
Rab2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000022765Ras-related protein Rab-2B; Required for protein transport from the endoplasmic reticulum to the Golgi complex; Belongs to the small GTPase superfamily. Rab family.
Tox4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022766TOX high mobility group box family member 4; Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transitio [...]
Mettl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022767N6-adenosine-methyltransferase subunit METTL3; The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some RNAs and regulat [...]
Lrp10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022782Low-density lipoprotein receptor-related protein 10; Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake [...]
Haus4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022784HAUS augmin-like complex subunit 4; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
4931414P19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000022786Uncharacterized protein C14orf93 homolog.
Slc7a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022787Large neutral amino acids transporter small subunit 2; Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalani [...]
Fbxo4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022791F-box only protein 4; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradatio [...]
Acin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022793Apoptotic chromatin condensation inducer in the nucleus; Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a [...]
Psmb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022803Proteasome subunit beta type-5; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles wi [...]
Bcl2l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022806Bcl-2-like protein 2; Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX. Belongs to the [...]
Pabpn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022808Polyadenylate-binding protein 2; Involved in the 3'-end formation of mRNA precursors (pre- mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly( [...]
Efs protein networkhttps://string-db.org/network/10090.ENSMUSP00000022813Embryonal Fyn-associated substrate; Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a do [...]
Ngdn protein networkhttps://string-db.org/network/10090.ENSMUSP00000022815Neuroguidin; Inhibits mRNA translation in a cytoplasmic polyadenylation element (CPE)-dependent manner; Belongs to the SAS10 family.
Sub1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022816Activated RNA polymerase II transcriptional coactivator p15; General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the ge [...]
Jph4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022819Junctophilin-4; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. [...]
Dhrs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022820Dehydrogenase/reductase member 2.
Dhrs4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022821Dehydrogenase/reductase SDR family member 4; Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficien [...]
Fitm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022826Fat storage-inducing transmembrane protein 1; Plays an important role in lipid droplet accumulation.
Emc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022828ER membrane protein complex subunit 9; Belongs to the EMC8/EMC9 family.
Ripk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022830Receptor-interacting serine/threonine-protein kinase 3; Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necros [...]
Khnyn protein networkhttps://string-db.org/network/10090.ENSMUSP00000022831Protein KHNYN; Belongs to the N4BP1 family.
Cma1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022834Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion; Belongs to the peptidase [...]
Mcpt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022836Mast cell protease 1; Has a chymotrypsin-like activity.
Cct5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022842T-complex protein 1 subunit epsilon; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC comp [...]
Tars protein networkhttps://string-db.org/network/10090.ENSMUSP00000022849Threonine--tRNA ligase 1, cytoplasmic; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the [...]
Brix1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022855Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family.
Rad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022856Cell cycle checkpoint protein RAD1; Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage b [...]
Ttc23l protein networkhttps://string-db.org/network/10090.ENSMUSP00000022857Tetratricopeptide repeat protein 23-like.
Agxt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022858Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is [...]
Ugt3a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022861UDP-glucuronosyltransferase 3A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water so [...]
Mtdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000022865Protein LYRIC; Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent grow [...]
Laptm4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000022867Lysosomal-associated transmembrane protein 4B; Required for optimal lysosomal function. Blocks EGF- stimulated EGFR intraluminal sorting and degradation. Conversely by binding with the phosphatid [...]
Sdc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022871Syndecan-2; Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis.
Ank protein networkhttps://string-db.org/network/10090.ENSMUSP00000022875Progressive ankylosis protein; Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter; Belongs to the ANKH family.
Retreg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022881Reticulophagy regulator 1; Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes. Promotes membrane remodeling and E [...]
Rnf19a protein networkhttps://string-db.org/network/10090.ENSMUSP00000022890E3 ubiquitin-protein ligase RNF19A; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transf [...]
Ywhaz protein networkhttps://string-db.org/network/10090.ENSMUSP0000002289414-3-3 protein zeta/delta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by rec [...]
Grhl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022895Grainyhead-like protein 2 homolog; Transcription factor playing an important role in primary neurulation and in epithelial development. Binds directly to the consensus DNA sequence 5'-AACCGGTT-3' [...]
Rrm2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000022901Ribonucleoside-diphosphate reductase subunit M2 B; Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in c [...]
Atp6v1c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022904V-type proton ATPase subunit C 1; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a sp [...]
Slc25a32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022908Mitochondrial folate transporter/carrier; Transports folate across the inner membranes of mitochondria. Can also transport FAD across the mitochondrial inner membrane (By similarity).
Dcaf13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022909DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to [...]
Dcstamp protein networkhttps://string-db.org/network/10090.ENSMUSP00000022913Dendritic cell-specific transmembrane protein; Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF [...]
Dpys protein networkhttps://string-db.org/network/10090.ENSMUSP00000022915Dihydropyrimidinase; Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrou [...]
Lrp12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022916Low-density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppres [...]
Angpt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022921Angiopoietin-1; Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell surviv [...]
Eif3h protein networkhttps://string-db.org/network/10090.ENSMUSP00000022925Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein [...]
Rad21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022927Double-strand-break repair protein rad21 homolog; [Double-strand-break repair protein rad21 homolog]: As a member of the cohesin complex, involved in sister chromatid cohesion from the time of DN [...]
Shcbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022945SHC SH2 domain-binding protein 1; May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstre [...]
Rida protein networkhttps://string-db.org/network/10090.ENSMUSP000000229462-iminobutanoate/2-iminopropanoate deaminase; Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of a [...]
Matn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022947Matrilin-2; Involved in matrix assembly.
Osr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022952Protein odd-skipped-related 2.
Fam135b protein networkhttps://string-db.org/network/10090.ENSMUSP00000022953Protein FAM135B; Belongs to the FAM135 family.
Khdrbs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022954KH domain-containing, RNA-binding, signal transduction-associated protein 3; RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site select [...]
Eif3e protein networkhttps://string-db.org/network/10090.ENSMUSP00000022960Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein [...]
Emc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022962ER membrane protein complex subunit 2; Belongs to the EMC2 family.
Kcnv1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022967Potassium voltage-gated channel subfamily V member 1; Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the thresh [...]
Myc protein networkhttps://string-db.org/network/10090.ENSMUSP00000022971Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth [...]
Washc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022976WASH complex subunit 5; Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in [...]
Sqle protein networkhttps://string-db.org/network/10090.ENSMUSP00000022977Squalene monooxygenase; Catalyzes the stereospecific oxidation of squalene to (S)- 2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
Ndufb9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022980NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved [...]
Klhl38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022985Kelch-like protein 38.
Fbxo32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022986F-box only protein 32; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradat [...]
Tbc1d31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022992TBC1 domain family member 31.
Derl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000022993Derlin-1; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded [...]
Mtbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000022998Mdm2-binding protein; May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediate [...]
Lrrc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023006Protein tilB homolog; May play a role in dynein arm assembly, hence essential for proper axoneme building for cilia motility; Belongs to the tilB family.
Adcy8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023007Adenylate cyclase type 8; Catalyzes the formation of cAMP in response to calcium entry leadings to cAMP signaling activation that affect processes suche as synaptic plasticity and insulin secreti [...]
Trmu protein networkhttps://string-db.org/network/10090.ENSMUSP00000023019Mitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation o [...]
Tef protein networkhttps://string-db.org/network/10090.ENSMUSP00000023024Thyrotroph embryonic factor; Transcription factor that binds to and transactivates the TSHB promoter. Binds to a minimal DNA-binding sequence 5'- [TC][AG][AG]TTA[TC][AG]-3' (By similarity). Also [...]
Rbx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023036E3 ubiquitin-protein ligase RBX1, N-terminally processed; E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase (CRLs) complexes which mediate the ubiquitination [...]
Slc25a17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023040Peroxisomal membrane protein PMP34; Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine m [...]
Adsl protein networkhttps://string-db.org/network/10090.ENSMUSP00000023043Adenylosuccinate lyase; Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate (SAICAR) to fumarate plus 5- [...]
Fam83f protein networkhttps://string-db.org/network/10090.ENSMUSP00000023044Protein FAM83F; Belongs to the FAM83 family.
Mief1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023048Mitochondrial dynamics protein MID51; Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related [...]
Tab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023050TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.
Dnal4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023055Dynein light chain 4, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity).
Nptxr protein networkhttps://string-db.org/network/10090.ENSMUSP00000023057Neuronal pentraxin receptor; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of [...]
Dscc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023059Sister chromatid cohesion protein DCC1; Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid coh [...]
Josd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023061Josephin-1; Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly- ubiquitin chains (in vitro), hence may act as a deubiquitina [...]
Tomm22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023062Mitochondrial import receptor subunit TOM22 homolog; Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and transloc [...]
Cby1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023064Protein chibby homolog 1; Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta- catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF tra [...]
Dmc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023065Meiotic recombination protein DMC1/LIM15 homolog; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double- [...]
Ribc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023067RIB43A-like with coiled-coils protein 2; Belongs to the RIB43A family.
Smc1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000023068Structural maintenance of chromosomes protein 1B; Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its esta [...]
Upk3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000023070Uroplakin-3a; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoske [...]
Samm50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023071Sorting and assembly machinery component 50 homolog; Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory cha [...]
Parvb protein networkhttps://string-db.org/network/10090.ENSMUSP00000023072Beta-parvin; Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorg [...]
C1qtnf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023075Complement C1q tumor necrosis factor-related protein 6.
Cyp2d22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023083Cytochrome P450, family 2, subfamily d, polypeptide 22; Belongs to the cytochrome P450 family.
Ndufa6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023085NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved [...]
Smdt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023086Essential MCU regulator, mitochondrial; Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria. Required t [...]
Twf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023087Twinfilin-1; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also [...]
Naga protein networkhttps://string-db.org/network/10090.ENSMUSP00000023088Alpha-N-acetylgalactosaminidase; Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids (By similarity); Belongs to th [...]
Wbp2nl protein networkhttps://string-db.org/network/10090.ENSMUSP00000023089Postacrosomal sheath WW domain-binding protein; May play a role in meotic resumption and pronuclear formation, mediated by a WW domain-signaling pathway during fertilization.
Sept3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023095Neuronal-specific septin-3; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Slc38a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023099Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids a [...]
Srebf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023100Processed sterol regulatory element-binding protein 2; Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to [...]
Slc38a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023101Sodium-coupled neutral amino acid transporter 4; Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a pre [...]
Rpap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023104RNA polymerase II-associated protein 3; Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to r [...]
Endou protein networkhttps://string-db.org/network/10090.ENSMUSP00000023105Poly(U)-specific endoribonuclease; Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2'-3'-cyclic phosphate termini; Belongs to the ENDOU family.
Pmm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023112Phosphomannomutase 1; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible f [...]
Polr3h protein networkhttps://string-db.org/network/10090.ENSMUSP00000023113DNA-directed RNA polymerase III subunit RPC8; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripher [...]
Aco2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023116Aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate; Belongs to the aconitase/IPM isomerase family.
Phf5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000023117PHD finger-like domain-containing protein 5A; Involved with the PAF1 complex (PAF1C) in transcriptional elongation by RNA polymerase II, and in regulation of development and maintenance of embryo [...]
Vdr protein networkhttps://string-db.org/network/10090.ENSMUSP00000023119Vitamin D3 receptor; Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (By similarity). Enters the nucleus upon vitamin D3 binding [...]
Col2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023123Collagen alpha-1(II) chain; Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of [...]
Itga5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023128Integrin alpha-5 heavy chain; Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via [...]
Gtsf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023129Gametocyte-specific factor 1; Required for spermatogenesis and is involved in the suppression of retrotransposon transcription in male germ cells.
Pde1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000023132Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regul [...]
Ppp1r1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000023133Protein phosphatase 1 regulatory subunit 1A; Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP [...]
Glycam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023134Glycosylation-dependent cell adhesion molecule 1; Adhesion molecule that accomplishes cell binding by presenting carbohydrate(s) to the lectin domain of L-selectin; Belongs to the PP3/GlyCAM-1 fa [...]
Tnfrsf17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023140Tumor necrosis factor receptor superfamily member 17; Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates [...]
Litaf protein networkhttps://string-db.org/network/10090.ENSMUSP00000023143Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog; Plays a role in endosomal protein trafficking and in targeting proteins for lysosomal degradation. Plays a role in targeting [...]
Prm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023144Sperm protamine P1; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive c [...]
Nubp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023146Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP [...]
Ciita protein networkhttps://string-db.org/network/10090.ENSMUSP00000023147MHC class II transactivator; Essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected [...]
1810013L24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000023150UPF0472 protein C16orf72 homolog; Belongs to the UPF0472 family.
Bcl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023151B-cell lymphoma 6 protein homolog; Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific [...]
Cldn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023154Claudin-1; Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the forma [...]
Anks3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023157Ankyrin repeat and SAM domain-containing protein 3; May be involved in vasopressin signaling in the kidney.
Srl protein networkhttps://string-db.org/network/10090.ENSMUSP00000023161Sarcalumenin; May be involved in the regulation of calcium transport.
Crebbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000023165Histone lysine acetyltransferase CREBBP; Acetylates histones, giving a specific tag for transcriptional activation (By similarity). Also acetylates non-histone proteins, like DDX21, FBL, IRF2, MA [...]
Hes1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023171Transcription factor HES-1; Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MY [...]
Zfp263 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023176Zinc finger protein 263.
Gpt protein networkhttps://string-db.org/network/10090.ENSMUSP00000023203Alanine aminotransferase 1; Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liv [...]
Ercc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023206DNA repair endonuclease XPF; Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that [...]
Cyc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023210Cytochrome c1, heme protein, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain [...]
Sharpin protein networkhttps://string-db.org/network/10090.ENSMUSP00000023211Sharpin; Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflamm [...]
Hgh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023213Protein HGH1 homolog; Belongs to the HGH1 family.
Dgat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023214Diacylglycerol O-acyltransferase 1; Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it i [...]
Bop1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023217Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Fbxl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023219F-box/LRR-repeat protein 6; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Slc52a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023220Solute carrier family 52, riboflavin transporter, member 2; Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemic [...]
Gpaa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023221Glycosylphosphatidylinositol anchor attachment 1 protein; Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate [...]
Grina protein networkhttps://string-db.org/network/10090.ENSMUSP00000023225Protein lifeguard 1; Potential apoptotic regulator; Belongs to the BI1 family. LFG subfamily.
Naprt protein networkhttps://string-db.org/network/10090.ENSMUSP00000023237Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and [...]
Gsdmd protein networkhttps://string-db.org/network/10090.ENSMUSP00000023238Gasdermin-D, C-terminal; [Gasdermin-D, N-terminal]: Promotes pyroptosis in response to microbial infection and danger signals. Produced by the cleavage of gasdermin-D by inflammatory caspases CAS [...]
Gpihbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023243Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells [...]
Ly6f protein networkhttps://string-db.org/network/10090.ENSMUSP00000023247Lymphocyte antigen 6F.
Ly6i protein networkhttps://string-db.org/network/10090.ENSMUSP00000023250Lymphocyte antigen 6I.
Lynx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023259Ly-6/neurotoxin-like protein 1; Acts in different tissues through interaction to nicotinic acetylcholine receptors (nAChRs). The proposed role as modulator of nAChR activity seems to be dependent [...]
Lypd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023260Ly6/PLAUR domain-containing protein 2.
Psca protein networkhttps://string-db.org/network/10090.ENSMUSP00000023265Prostate stem cell antigen; May be involved in the regulation of cell proliferation.
Arc protein networkhttps://string-db.org/network/10090.ENSMUSP00000023268Activity-regulated cytoskeleton-associated protein; Master regulator of synaptic plasticity that self-assembles into virion-like capsids that encapsulate RNAs and mediate intercellular RNA transf [...]
Rpl24 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002326960S ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family.
Cep97 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023270Centrosomal protein of 97 kDa; Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recru [...]
Mroh4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023271Maestro heat-like repeat family member 4.
Miox protein networkhttps://string-db.org/network/10090.ENSMUSP00000023282Inositol oxygenase.
Lmf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023283Lipase maturation factor 2; Involved in the maturation of specific proteins in the endoplasmic reticulum. May be required for maturation and transport of active lipoprotein lipase (LPL) through t [...]
Tymp protein networkhttps://string-db.org/network/10090.ENSMUSP00000023285Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucle [...]
Chkb protein networkhttps://string-db.org/network/10090.ENSMUSP00000023289Choline/ethanolamine kinase; Has a key role in phospholipid metabolism, and catalyzes the first step of phosphatidylethanolamine and phosphatidylcholine biosynthesis; Belongs to the choline/ethan [...]
Mapk8ip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023291C-Jun-amino-terminal kinase-interacting protein 2; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK c [...]
Rabl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023294Rab-like protein 2A; Plays an essential role in male fertility, sperm intra- flagellar transport, and tail assembly. Binds, in a GTP-regulated manner, to a specific set of effector proteins inclu [...]
Acr protein networkhttps://string-db.org/network/10090.ENSMUSP00000023295Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stor [...]
Alcam protein networkhttps://string-db.org/network/10090.ENSMUSP00000023312CD166 antigen; Cell adhesion molecule that mediates both heterotypic cell- cell contacts via its interaction with CD6, as well as homotypic cell- cell contacts. Promotes T-cell activation and pro [...]
Retnlb protein networkhttps://string-db.org/network/10090.ENSMUSP00000023328Resistin-like beta; Probable hormone.
Retnla protein networkhttps://string-db.org/network/10090.ENSMUSP00000023329Resistin-like alpha; Probable hormone. Plays a role in pulmonary vascular remodeling; Belongs to the resistin/FIZZ family.
Morc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023330MORC family CW-type zinc finger protein 1; Required for spermatogenesis.
Nectin3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023334Nectin-3; Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectins-like or other nectins, such as trans- interaction with NECTIN2 at Sertoli-spermatid junctions. Tr [...]
Cd96 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023336T-cell surface protein tactile; May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting [...]
Atg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023343Ubiquitin-like-conjugating enzyme ATG3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent [...]
Slc35a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023344Probable UDP-sugar transporter protein SLC35A5.
Mzt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023351Mitotic-spindle organizing protein 2; Belongs to the MOZART2 family.
Prkdc protein networkhttps://string-db.org/network/10090.ENSMUSP00000023352DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage (By similarity). Involved in DNA non-homologous end joining (NHEJ) r [...]
Mcm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023353DNA replication licensing factor MCM4; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiat [...]
Snai2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023356Zinc finger protein SNAI2; Transcriptional repressor that modulates both activator- dependent and basal transcription. Involved in the generation and migration of neural crest cells. Plays a role [...]
Fopnl protein networkhttps://string-db.org/network/10090.ENSMUSP00000023357LisH domain-containing protein FOPNL; Involved in the biogenesis of cilia (By similarity). Required for the recruitment of PLK1 to centrosomes and S phase progression (By similarity).
Nde1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023359Nuclear distribution protein nudE homolog 1; Required for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regul [...]
Mpv17l protein networkhttps://string-db.org/network/10090.ENSMUSP00000023360Mpv17-like protein; Isoform 1 and isoform 3 participate in reactive oxygen species metabolism by up- or down-regulation of the genes of antioxidant enzymes; Belongs to the peroxisomal membrane pr [...]
Pdxdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023361Pyridoxal-dependent decarboxylase domain-containing protein 1; Belongs to the group II decarboxylase family.
Ntan1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023362Protein N-terminal asparagine amidohydrolase; N-terminal asparagine deamidase that mediates deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnov [...]
Rrn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023363RNA polymerase I-specific transcription initiation factor RRN3; Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation comp [...]
Pla2g10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023364Group 10 secretory phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Has a powerful potency for releasing arachidonic acid from cell [...]
Bfar protein networkhttps://string-db.org/network/10090.ENSMUSP00000023365Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity).
Qtrt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023387Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) [...]
Drd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023390D(3) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity); Belongs to the G-protein coupled re [...]
Mrpl40 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002339139S ribosomal protein L40, mitochondrial.
Pmm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023396Phosphomannomutase 2; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
Tmem114 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023400Transmembrane protein 114.
Cldnd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023426Claudin domain-containing protein 1.
Tbc1d23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023431TBC1 domain family member 23; Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding [...]
Nit2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023432Omega-amidase NIT2; Possesses omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically us [...]
Tmem30c protein networkhttps://string-db.org/network/10090.ENSMUSP00000023434Cell cycle control protein 50C; Belongs to the CDC50/LEM3 family.
Tmem45a protein networkhttps://string-db.org/network/10090.ENSMUSP00000023435Transmembrane protein 45A.
Adgrg7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023437Adhesion G-protein coupled receptor G7; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
P2rx6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023441P2X purinoceptor 6; Receptor for ATP that acts as a ligand-gated ion channel.
Lztr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023444Leucine-zipper-like transcriptional regulator 1; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (K-Ras/KRAS, N-Ras/NRA [...]
Snap29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023449Synaptosomal-associated protein 29; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on op [...]
Serpind1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023450Heparin cofactor 2; Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place o [...]
Ccdc116 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023452Coiled-coil domain-containing protein 116.
Sdf2l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023453Stromal cell-derived factor 2-like protein 1.
Ncbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023460Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mR [...]
Meltf protein networkhttps://string-db.org/network/10090.ENSMUSP00000023464Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc; Belongs t [...]
Top3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000023465DNA topoisomerase 3-beta-1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the [...]
Pak2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023467Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle [...]
Spag6l protein networkhttps://string-db.org/network/10090.ENSMUSP00000023468Sperm-associated antigen 6; Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility.
Wdr53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023474WD repeat-containing protein 53; Belongs to the WD repeat WDR53 family.
Igsf11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023478Immunoglobulin superfamily member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth (By similarity).
B4galt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023482Beta-1,4-galactosyltransferase 4; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the [...]
Tfrc protein networkhttps://string-db.org/network/10090.ENSMUSP00000023486Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads [...]
Arhgap31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023487Rho GTPase-activating protein 31; Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42. Required for cell spreading, polarized lamellipodia formation and cell migration.
Fyttd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023489UAP56-interacting factor; Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to [...]
Popdc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023494Popeye domain-containing protein 2; Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, pro [...]
Lmln protein networkhttps://string-db.org/network/10090.ENSMUSP00000023497Leishmanolysin-like peptidase; Metalloprotease.
Maats1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023501Cilia- and flagella-associated protein 91; May regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity). May play a role in spermatogenesis.
Snx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023502Sorting nexin-4; Involved in the regulation of endocytosis and in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradati [...]
Nr1i2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023504Nuclear receptor subfamily 1 group I member 2; Nuclear receptor that binds and is activated by a variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcript [...]
Klhl24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023509Kelch-like protein 24; Controls KRT14 levels during keratinocytes differentiation. As part of the BCR(KLHL24) E3 ubiquitin ligase complex, mediates ubiquitination of KRT14 (By similarity). Specif [...]
Umps protein networkhttps://string-db.org/network/10090.ENSMUSP00000023510Orotidine 5'-phosphate decarboxylase; In the C-terminal section; belongs to the OMP decarboxylase family.
Ndufb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023514NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved [...]
Rabl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023524Rab-like protein 3.
Gtf2e1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023525General transcription factor IIE subunit 1; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Bo [...]
Ropn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023530Ropporin-1; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacit [...]
Hcls1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023531Hematopoietic lineage cell-specific protein; Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lympho [...]
Ccdc14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023532Coiled-coil domain-containing protein 14; Negatively regulates centriole duplication. Negatively regulates CEP63 and CDK2 centrosomal localization.
Iqcb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023535IQ calmodulin-binding motif-containing protein 1; Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6 (By similarity). Involved [...]
Mylk protein networkhttps://string-db.org/network/10090.ENSMUSP00000023538Myosin light chain kinase, smooth muscle, deglutamylated form; Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light c [...]
Pdia5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023550Protein disulfide-isomerase A5.
Slc49a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023554Solute carrier family 49 member 4; Electrogenic metabolite transporter.
Ehhadh protein networkhttps://string-db.org/network/10090.ENSMUSP00000023559Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
Senp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023561Sentrin-specific protease 2; Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ub [...]
Tmem41a protein networkhttps://string-db.org/network/10090.ENSMUSP00000023562Transmembrane protein 41A; Belongs to the TMEM41 family.
Tmprss15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023566Enteropeptidase non-catalytic heavy chain; Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion o [...]
Chodl protein networkhttps://string-db.org/network/10090.ENSMUSP00000023568Chondrolectin; May play a role in the development of the nervous system such as in neurite outgrowth and elongation. May be involved in motor axon growth and guidance (By similarity).
Btg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023570Protein BTG3; Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase; Belongs to the BTG family.
Cxadr protein networkhttps://string-db.org/network/10090.ENSMUSP00000023572Coxsackievirus and adenovirus receptor homolog; Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction in [...]
Usp25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023580Ubiquitin carboxyl-terminal hydrolase 25; Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycl [...]
Ahsg protein networkhttps://string-db.org/network/10090.ENSMUSP00000023583Alpha-2-HS-glycoprotein; Probably involved in differentiation; Belongs to the fetuin family.
Kng1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023589Kininogen-1 heavy chain; (1) Kininogens are inhibitors of thiol proteases; (2) HMW- kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and facto [...]
Hrg protein networkhttps://string-db.org/network/10090.ENSMUSP00000023590Histidine-rich glycoprotein; Plasma glycoprotein that binds a number of ligands such as heme, heparin, heparan sulfate, thrombospondin, plasminogen, and divalent metal ions. Binds heparin and hep [...]
Adipoq protein networkhttps://string-db.org/network/10090.ENSMUSP00000023593Adiponectin; Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK p [...]
Rfc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023598Replication factor C subunit 4; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) [...]
Robo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023600Roundabout homolog 1; Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neu [...]
St6gal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023601Beta-galactoside alpha-2,6-sialyltransferase 1; Transfers sialic acid from CMP-sialic acid to galactose- containing acceptor substrates.
Prl2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023602Prolactin-2A1; Belongs to the somatotropin/prolactin family.
Atp5j protein networkhttps://string-db.org/network/10090.ENSMUSP00000023608ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membr [...]
Adamts1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023610A disintegrin and metalloproteinase with thrombospondin motifs 1; Cleaves aggrecan, a cartilage proteoglycan, at the '1691- Glu-|-Leu-1692' site (within the chondroitin sulfate attachment domain) [...]
Adamts5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023611A disintegrin and metalloproteinase with thrombospondin motifs 5; Metalloproteinase that plays an important role in connective tissue organization, development, inflammation, arthritis, and cell [...]
Ets2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023612Protein C-ets-2; Transcription factor activating transcription. Binds specifically the GGA DNA motif in gene promoters and stimulates transcription of those genes (By similarity).
Vps26c protein networkhttps://string-db.org/network/10090.ENSMUSP00000023615Vacuolar protein sorting-associated protein 26C; Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) an [...]
Slc15a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023616Solute carrier family 15 member 2; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports the dipeptide-like aminopeptidase inhibitor bestatin ( [...]
Ildr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023617Immunoglobulin-like domain-containing receptor 1; Putative membrane receptor; Belongs to the immunoglobulin superfamily. LISCH7 family.
Stfa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023619Cystatin-A/B.
Pros1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023629Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and st [...]
Psmg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023630Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 prot [...]
Ripply3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023660Protein ripply3; Acts as a transcriptional corepressor. Negative regulator of the transcriptional activity of TBX1. Plays a role in the development of the pharyngeal apparatus and derivatives.
Chaf1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000023666Chromatin assembly factor 1 subunit B; Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 per [...]
Clic6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023670Chloride intracellular channel protein 6; May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride [...]
Runx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023673Runt-related transcription factor 1; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the cor [...]
Atp5o protein networkhttps://string-db.org/network/10090.ENSMUSP00000023677ATP synthase subunit O, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
Donson protein networkhttps://string-db.org/network/10090.ENSMUSP00000023682Protein downstream neighbor of Son; Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for [...]
Gart protein networkhttps://string-db.org/network/10090.ENSMUSP00000023684Trifunctional purine biosynthetic protein adenosine-3; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family.
Tmem50b protein networkhttps://string-db.org/network/10090.ENSMUSP00000023686Transmembrane protein 50B; Belongs to the UPF0220 family.
Ifngr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023687Interferon gamma receptor 2.
Ifnar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023689Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2 (By similarity). [...]
Il10rb protein networkhttps://string-db.org/network/10090.ENSMUSP00000023691Interleukin-10 receptor subunit beta; Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor [...]
Ifnar2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023693Interferon alpha/beta receptor 2; Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN- mediated STAT1, STAT2 and STAT3 activati [...]
Cfap298 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023694Cilia- and flagella-associated protein 298; Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly. Seems to be important for initiation rather than maintenance o [...]
Sod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023707Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family.
Krt5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023709Keratin, type II cytoskeletal 5.
Krt71 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023710Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle.
Krt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023712Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification (By similarity). Associated with keratinocyte activation, proliferation and keratinization (By similarity [...]
Krt82 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023713Keratin, type II cuticular Hb2; Belongs to the intermediate filament family.
Krt90 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023714Keratin 90; Belongs to the intermediate filament family.
Krt83 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023718Keratin 83; Belongs to the intermediate filament family.
Krt84 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023720Keratin, type II cuticular Hb4; Belongs to the intermediate filament family.
Lalba protein networkhttps://string-db.org/network/10090.ENSMUSP00000023726Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme [...]
Wnt10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000023732Protein Wnt-10b; Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade. Specifically activates canonical Wnt/beta-catenin signaling and [...]
Wnt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023734Proto-oncogene Wnt-1; Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional a [...]
Lmbr1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000023736Protein LMBR1L; Plays an essential role in lymphocyte development by negatively regulating the canonical Wnt signaling pathway. In association with UBAC2 and E3 ubiquitin-protein ligase AMFR, pro [...]
Dhh protein networkhttps://string-db.org/network/10090.ENSMUSP00000023737Desert hedgehog protein C-product; Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential fo [...]
Kmt2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000023741Histone-lysine N-methyltransferase 2D; Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a [...]
Nckap5l protein networkhttps://string-db.org/network/10090.ENSMUSP00000023747Nck-associated protein 5-like; Regulates microtubule organization and stabilization. Promotes microtubule growth and bundling formation and stabilizes microtubules by increasing intense acetylati [...]
Tmbim6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023749Bax inhibitor 1; Suppressor of apoptosis (By similarity). Modulates unfolded protein response signaling (By similarity). Modulates ER calcium homeostasis by acting as a calcium-leak channel (By s [...]
Faim2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023750Protein lifeguard 2; Antiapoptotic protein which protects cells uniquely from Fas- induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. Plays a [...]
Aqp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023752Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an os [...]
Aqp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023754Aquaporin-6; Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism.
Asic1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023758Acid-sensing ion channel 1; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactiva [...]
Smarcd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023759SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alter [...]
Gpd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023760Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic.
Cox14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023761Cytochrome c oxidase assembly protein COX14; Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cyto [...]
Cers5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023762Ceramide synthase 5; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward palmitoyl-CoA (hexadecanoyl-CoA; C16:0-CoA) as a [...]
Atf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023769Cyclic AMP-dependent transcription factor ATF-1; Binds the cAMP response element (CRE) (consensus: 5'- GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the T [...]
Slc11a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023774Natural resistance-associated macrophage protein 2; May serve to import iron into the mitochondria (By similarity). Important in metal transport, in particular iron. Involved in apical iron uptak [...]
Cela1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023775Chymotrypsin-like elastase family member 1; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily.
Slc4a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023776Electroneutral sodium bicarbonate exchanger 1; Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in p [...]
Krt88 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023781Keratin 88; Belongs to the intermediate filament family.
Krt6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000023786Keratin, type II cytoskeletal 6B; Belongs to the intermediate filament family.
Krt6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000023788Keratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a majo [...]
Krt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023790Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In comple [...]
Krt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023797Keratin, type II cytoskeletal 4.
Krt79 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023799Keratin, type II cytoskeletal 79; Belongs to the intermediate filament family.
Krt18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023803Keratin, type I cytoskeletal 18; When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin- [...]
Csad protein networkhttps://string-db.org/network/10090.ENSMUSP00000023805Cysteine sulfinic acid decarboxylase; Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L- alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respect [...]
Soat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023806Sterol O-acyltransferase 2; Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl e [...]
Igfbp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023807Insulin-like growth factor-binding protein 6; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on [...]
Amhr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023809Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphoryla [...]
Map3k12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023812Mitogen-activated protein kinase kinase kinase 12; Protein kinase which is part of a non-canonical MAPK signaling pathway. Activated by APOE, enhances the AP-1-mediated transcription of APP, via [...]
Tarbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023813RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading c [...]
Npff protein networkhttps://string-db.org/network/10090.ENSMUSP00000023814Pro-FMRFamide-related neuropeptide FF; Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pre [...]
Calcoco1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023818Calcium-binding and coiled-coil domain-containing protein 1; Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N- ter [...]
Fabp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023820Fatty acid-binding protein, intestinal; FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglycer [...]
Sncg protein networkhttps://string-db.org/network/10090.ENSMUSP00000023826Gamma-synuclein; Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of [...]
Rttn protein networkhttps://string-db.org/network/10090.ENSMUSP00000023828Rotatin; Involved in the genetic cascade that governs left-right specification. Required for correct asymmetric expression of NODAL, LEFTY and PITX2 (By similarity).
Nus1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023830Dehydrodolichyl diphosphate synthase complex subunit Nus1; With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) b [...]
Rgn protein networkhttps://string-db.org/network/10090.ENSMUSP00000023832Regucalcin; Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis. Can also [...]
Slc10a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023835Ileal sodium/bile acid cotransporter; Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism (B [...]
Mospd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023836Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). Ho [...]
Cxcl13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023840C-X-C motif chemokine 13; Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in [...]
H2-M10.2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023845Histocompatibility 2, M region locus 10.2; Belongs to the MHC class I family.
Lrrc71 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023846Leucine-rich repeat-containing protein 71.
Noct protein networkhttps://string-db.org/network/10090.ENSMUSP00000023849Nocturnin; Phosphatase which catalyzes the conversion of NADP(+) to NAD(+) and of NADPH to NADH (By similarity). Shows a small preference for NADPH over NADP(+) (By similarity). Represses transla [...]
Ndufa5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023851NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved [...]
Msrb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023856Methionine-R-sulfoxide reductase B2, mitochondrial; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation [...]
Serpinb3d protein networkhttps://string-db.org/network/10090.ENSMUSP00000023861Serine (Or cysteine) peptidase inhibitor, clade B (Ovalbumin), member 3D; Belongs to the serpin family.
Rfc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023867Replication factor C subunit 2; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) [...]
Denr protein networkhttps://string-db.org/network/10090.ENSMUSP00000023869Density-regulated protein; May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitment of amin [...]
Prmt5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023873Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a prefere [...]
Sympk protein networkhttps://string-db.org/network/10090.ENSMUSP00000023882Symplekin; Scaffold protein that functions as a component of a multimolecular complex involved in histone mRNA 3'-end processing. Specific component of the tight junction (TJ) plaque, but might n [...]
Ldc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023884Leucine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
Sult1c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023886Sulfotransferase 1C2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neu [...]
Gzma protein networkhttps://string-db.org/network/10090.ENSMUSP00000023897Granzyme A; Abundant protease in the cytosolic granules of cytotoxic T- cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered i [...]
Reg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023906Lithostathine-2; Might act as an inhibitor of spontaneous calcium carbonate precipitation.
Nagpa protein networkhttps://string-db.org/network/10090.ENSMUSP00000023911N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase; Catalyzes the second step in the formation of the mannose 6- phosphate targeting signal on lysosomal enzyme oligosaccharides by [...]
Wrb protein networkhttps://string-db.org/network/10090.ENSMUSP00000023913Tail-anchored protein insertion receptor WRB; Receptor for ASNA1/TRC40-mediated insertion of tail-anchored (TA) proteins into the ER membrane.
Lrrc69 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023917Leucine-rich repeat-containing protein 69; Belongs to the LRRC69 family.
Ivns1abp protein networkhttps://string-db.org/network/10090.ENSMUSP00000023918Influenza virus NS1A-binding protein homolog; Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitin [...]
Rpp14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023924Ribonuclease P protein subunit p14; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNa [...]
Ssxb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023931Synovial sarcoma, X member B2.
Hbb-bs protein networkhttps://string-db.org/network/10090.ENSMUSP00000023934Hemoglobin subunit beta-1; Involved in oxygen transport from the lung to the various peripheral tissues.
Krt8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023952Keratin, type II cytoskeletal 8; Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle; Belongs to the intermediate filament family.
Ceacam14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023953Carcinoembryonic antigen-related cell adhesion molecule 14.
P3h3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023958Prolyl 3-hydroxylase 3; Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-l [...]
Grm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023959Metabotropic glutamate receptor 2; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G protein [...]
Cfhr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023965Complement factor H-related protein.
Lcn9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023978Epididymal-specific lipocalin-9.
Serping1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000023994Plasma protease C1 inhibitor; Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May pla [...]
Ccl25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024004C-C motif chemokine 25; Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on [...]
Scg5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024005Neuroendocrine protein 7B2; Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticul [...]
Kcnk5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024011Potassium channel, subfamily K, member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
Guca2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000024015Guanylin; Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.
Cypt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024026Cysteine-rich perinuclear theca protein 1.
Acy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024031Aminoacylase-1; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate); Belongs to the peptidase M20A family.
9530002B09Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000024032RIKEN cDNA 9530002B09 gene.
Gabrr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024035Gamma-aminobutyric acid receptor subunit rho-2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor an [...]
Creld2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024042Protein disulfide isomerase Creld2; Protein disulfide isomerase (Probable). Might play a role in the unfolded protein response (Probable). May regulate transport of alpha4-beta2 neuronal acetylch [...]
Cd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024044T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal o [...]
Twf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024047Twinfilin-2; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also [...]
Bmp15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024049Bone morphogenetic protein 15; May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similar [...]
Ube2j2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024056Ubiquitin-conjugating enzyme E2 J2; Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endopl [...]
Sva protein networkhttps://string-db.org/network/10090.ENSMUSP00000024059Seminal vesicle antigen.
March5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024078E3 ubiquitin-protein ligase MARCHF5; Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondr [...]
Ache protein networkhttps://string-db.org/network/10090.ENSMUSP00000024099Acetylcholinesterase; Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
Gcm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024104Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other plac [...]
Wfdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024107WAP four-disulfide core domain protein 1; Has growth inhibitory activity.
Clec4n protein networkhttps://string-db.org/network/10090.ENSMUSP00000024118C-type lectin domain family 6 member A; Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the [...]
Trip6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024119Thyroid receptor-interacting protein 6; Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involv [...]
Agap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024123Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3; GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in the degradation o [...]
Kcnk16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024155Potassium channel, subfamily K, member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
Dlx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024159Homeobox protein DLX-2; Acts as a transcriptional activator. Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina. Likely to play [...]
Stk31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024171Serine/threonine-protein kinase 31.
Nfatc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024179Nuclear factor of activated T-cells, cytoplasmic 4; Ca(2+)-regulated transcription factor that is involved in several processes, including the development and function of the immune, cardiovascul [...]
Cela3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000024200Chymotrypsin-like elastase family, member 3A; Belongs to the peptidase S1 family.
Gnb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024206Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling sys [...]
Celsr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024238Cadherin EGF LAG seven-pass G-type receptor 3; Receptor that may have an important role in cell/cell signaling during nervous system formation; Belongs to the G-protein coupled receptor 2 family. [...]
Pcbp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024260Poly(rC)-binding protein 4; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC.
Cdca3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024270Cell division cycle-associated protein 3; F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation [...]
C1qtnf12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024338Adipolin fC1QTNF12; Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses [...]
Ogfod2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000244702-oxoglutarate and iron-dependent oxygenase domain-containing protein 2; Belongs to the OGFOD2 family.
Mrps23 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002448628S ribosomal protein S23, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS23 family.
Acbd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024492Acyl-Coenzyme A-binding domain-containing 4.
Rhebl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024518GTPase RhebL1; Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downst [...]
Hes7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024543Transcription factor HES-7; Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the preso [...]
Rsph3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000024572Radial spoke head protein 3 homolog B; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK [...]
Rps6ka2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024575Ribosomal protein S6 kinase alpha-2; Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of tran [...]
Agpat4 protein networkhttps://string-db.org/network/10090.ENSMUSP000000245941-acyl-sn-glycerol-3-phosphate acyltransferase delta; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by i [...]
Slc22a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024595Solute carrier family 22 member 3; Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmit [...]
Slc22a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024596Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- methyl-4-phenylpyridinium (MPP), te [...]
Igf2r protein networkhttps://string-db.org/network/10090.ENSMUSP00000024599Cation-independent mannose-6-phosphate receptor; Acts as a positive regulator of T-cell coactivation, by binding DPP4 (By similarity). Transport of phosphorylated lysosomal enzymes from the Golgi [...]
Riok2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024620Serine/threonine-protein kinase RIO2; Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosom [...]
Chd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024627Chromodomain-helicase-DNA-binding protein 1; ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) [...]
1700010I14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000024650RIKEN cDNA 1700010I14 gene.
Phf10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024657PHD finger protein 10; Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is requir [...]
Smoc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024660SPARC-related modular calcium-binding protein 2; Can stimulate endothelial cell proliferation, migration, as well as angiogenesis (By similarity). Promotes matrix assembly and cell adhesiveness.
Mmp25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024696Matrix metalloproteinase-25; May activate progelatinase A; Belongs to the peptidase M10A family.
Hcfc1r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024697Host cell factor C1 regulator 1; Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated e [...]
Tnfrsf12a protein networkhttps://string-db.org/network/10090.ENSMUSP00000024698Tumor necrosis factor receptor superfamily member 12A; Receptor for TNFSF12/TWEAK (By similarity). Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of end [...]
Cldn6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024699Claudin-6; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
Pkmyt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024701Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specific [...]
Paqr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024702Progestin and adipoQ receptor family member 4.
Flywch2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024704FLYWCH family member 2.
Slc25a27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024705Solute carrier family 25, member 27; Belongs to the mitochondrial carrier (TC 2.A.29) family.
Pla2g7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024706Platelet-activating factor acetylhydrolase; Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specific [...]
Mep1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000024707Meprin A subunit alpha.
Tnfrsf21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024708Tumor necrosis factor receptor superfamily member 21; Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the [...]
Cd2ap protein networkhttps://string-db.org/network/10090.ENSMUSP00000024709CD2-associated protein; Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton (By similarity). In collaboration with CBLC, modulates the rate of RET turnover and [...]
Adgrf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024711Adhesion G protein-coupled receptor F4; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Tbc1d5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024717TBC1 domain family member 5; May act as a GTPase-activating protein for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membra [...]
Rhag protein networkhttps://string-db.org/network/10090.ENSMUSP00000024721Ammonium transporter Rh type A; May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Involved in ammonia transport across the [...]
Efhb protein networkhttps://string-db.org/network/10090.ENSMUSP00000024725EF-hand domain-containing family member B; Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion, the activation of store-operated Ca(2+) entry (SOCE) an [...]
Cdc5l protein networkhttps://string-db.org/network/10090.ENSMUSP00000024727Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, ca [...]
Spats1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024731Spermatogenesis-associated serine-rich protein 1.
Aars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024733Alanine--tRNA ligase, mitochondrial; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the accept [...]
Mrpl14 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002473439S ribosomal protein L14, mitochondrial; May form part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1, intersubunit bridge formation is blocked, preventing ribosome [...]
Sgo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024736Shugoshin 1; Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex disso [...]
Sult1c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024738Sulfotransferase 1C1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neu [...]
Hsp90ab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024739Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle cont [...]
Nfkbie protein networkhttps://string-db.org/network/10090.ENSMUSP00000024742NF-kappa-B inhibitor epsilon; Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes (By similarity).
Gtpbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024748GTP-binding protein 2.
Polh protein networkhttps://string-db.org/network/10090.ENSMUSP00000024749DNA polymerase eta; DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS). Due to low processivity on both damaged and normal DNA, cooperates with the heterotetram [...]
Clic5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024755Chloride intracellular channel protein 5; Required for normal hearing (By similarity). It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Cor [...]
Enpp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024756Ectonucleotide pyrophosphatase/phosphodiesterase family member 5; Can hydrolyze NAD but cannot hydrolyze nucleotide di- and triphosphates. Lacks lysopholipase D activity. May play a role in neuro [...]
Enpp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024757Bis(5'-adenosyl)-triphosphatase enpp4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of v [...]
Fbxl17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024761F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF(FBXL17) E3 ubiquitin ligase complex, a key component of a quality control pathway required to ensure functional dimerizatio [...]
Rsph9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024762Radial spoke head protein 9 homolog; Probable component of the axonemal radial spoke head (By similarity). Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consis [...]
Mrps18a protein networkhttps://string-db.org/network/10090.ENSMUSP0000002476328S ribosomal protein S18a, mitochondrial; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily.
Rrp36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024766Ribosomal RNA processing protein 36 homolog; Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA; Belongs to the RRP36 family.
Prph2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024773Peripherin-2; Essential for retina photoreceptor outer segment disk morphogenesis, may also play a role with ROM1 in the maintenance of outer segment disk structure. Required for the maintenance [...]
Guca1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000024774Guanylyl cyclase-activating protein 2; Stimulates two retinal guanylyl cyclase (GCs) GUCY2E and GUCY2F when free calcium ions concentration is low, and inhibits GUCY2E and GUCY2F when free calciu [...]
Med20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024778Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Usp49 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024779Ubiquitin carboxyl-terminal hydrolase 49; Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a re [...]
Pgc protein networkhttps://string-db.org/network/10090.ENSMUSP00000024782Gastricsin; Hydrolyzes a variety of proteins.
Bysl protein networkhttps://string-db.org/network/10090.ENSMUSP00000024783Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family.
Tfeb protein networkhttps://string-db.org/network/10090.ENSMUSP00000024786Transcription factor EB; Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TF [...]
Tspo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024794Translocator protein 2; Binds cholesterol and mediates its redistribution during erythropoiesis which may play a role in erythrocyte maturation.
Ppil1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024802Peptidyl-prolyl cis-trans isomerase-like 1; Involved in pre-mRNA splicing as component of the spliceosome. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of [...]
Cpne5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024805Copine-5; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes. Plays a role in dendrite formation by melanocytes. Belongs to t [...]
Fgd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024810FYVE, RhoGEF and PH domain-containing protein 2; Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not [...]
Pim1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024811Serine/threonine-protein kinase pim-1; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigene [...]
Cmtr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024816Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Met [...]
Rnf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024817E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A a [...]
Tff2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024826Trefoil factor 2; Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel [...]
Tff3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024827Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).
Abcg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024829ATP-binding cassette sub-family G member 1; Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta- hydroxycholesterol and this transpo [...]
Tff1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024831Trefoil factor 1; Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents.
Rsph1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024832Radial spoke head 1 homolog; The specific expression during male germ cell development and its characteristic localization suggest that it may play an important role in male meiosis. It is necess [...]
Sik1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024839Serine/threonine-protein kinase SIK1; Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and di [...]
Arhgap28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024840Rho GTPase-activating protein 28; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Ndc80 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024851Kinetochore protein NDC80 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Require [...]
Clip4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024854CAP-Gly domain-containing linker protein 4.
Lbh protein networkhttps://string-db.org/network/10090.ENSMUSP00000024857Protein LBH; Modulates the activity of key transcription factors involved in cardiogenesis.
Galnt14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024858Polypeptide N-acetylgalactosaminyltransferase 14; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threo [...]
Ehd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024860EH domain-containing protein 3; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes (By simil [...]
Xdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000024866Xanthine dehydrogenase/oxidase; Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generat [...]
Spast protein networkhttps://string-db.org/network/10090.ENSMUSP00000024869Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with [...]
Yipf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024873Protein YIPF4; Involved in the maintenance of the Golgi structure. Belongs to the YIP1 family.
Vit protein networkhttps://string-db.org/network/10090.ENSMUSP00000024880Vitrin; Promotes matrix assembly and cell adhesiveness. Plays a role in spinal cord formation by regulating the proliferation and differentiation of neural stem cells.
Ttc27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024882Tetratricopeptide repeat protein 27.
Eif2ak2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024884Interferon-induced, double-stranded RNA-activated protein kinase; IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral infecti [...]
Cebpz protein networkhttps://string-db.org/network/10090.ENSMUSP00000024885CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family.
Ndufaf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024887Protein arginine methyltransferase NDUFAF7, mitochondrial; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Ac [...]
Cyp1b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024894Cytochrome P450 1B1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins (By similarity). Mechanistic [...]
Vapa protein networkhttps://string-db.org/network/10090.ENSMUSP00000024897Vesicle-associated membrane protein-associated protein A; Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites. The ORP3-VAPA complex stimulates RRAS signaling which in tu [...]
Ralbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024905RalA-binding protein 1; Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4- dinitrophenyl)-glutathione (DNP-SG) and doxo [...]
Twsg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024906Twisted gastrulation protein homolog 1; May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs [...]
Themis3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024914Protein THEMIS3.
Lhcgr protein networkhttps://string-db.org/network/10090.ENSMUSP00000024916Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Prss41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024926Serine protease 41; Belongs to the peptidase S1 family.
Prss21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024928Testisin; Could regulate proteolytic events associated with testicular germ cell maturation; Belongs to the peptidase S1 family.
Tedc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024930Tubulin epsilon and delta complex protein 2; Acts as a positive regulator of ciliary hedgehog signaling. Required for centriole stability.
Ntn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024931Netrin-3; Netrins control guidance of CNS commissural axons and peripheral motor axons.
Atp6v0c protein networkhttps://string-db.org/network/10090.ENSMUSP00000024932V-type proton ATPase 16 kDa proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of [...]
Slc3a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024944Neutral and basic amino acid transport protein rBAT; Involved in the high-affinity sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May f [...]
Epas1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024954Endothelial PAS domain-containing protein 1; Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG- [...]
Rhoq protein networkhttps://string-db.org/network/10090.ENSMUSP00000024956Rho-related GTP-binding protein RhoQ; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effec [...]
Pigf protein networkhttps://string-db.org/network/10090.ENSMUSP00000024957Phosphatidylinositol-glycan biosynthesis class F protein; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI. Belongs to the PIGF famil [...]
Caskin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024958Caskin-1; May link the scaffolding protein CASK to downstream intracellular effectors.
Cript protein networkhttps://string-db.org/network/10090.ENSMUSP00000024959Cysteine-rich PDZ-binding protein; Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses.
Mcfd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024963Multiple coagulation factor deficiency protein 2 homolog; The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.
Msh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024967DNA mismatch repair protein Msh2; Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 [...]
Gtf2a1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000024970TFIIA-alpha and beta-like factor; May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows [...]
Meiob protein networkhttps://string-db.org/network/10090.ENSMUSP00000024972Meiosis-specific with OB domain-containing protein; Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and cro [...]
Nme3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024978Nucleoside diphosphate kinase 3; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism [...]
Jpt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024981Jupiter microtubule associated homolog 2.
Ift140 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024983Intraflagellar transport protein 140 homolog; Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPC [...]
Tmem204 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024984Transmembrane protein 204; Can influence paracellular permeability. Appears to be involved in cell-cell interactions through adherens (By similarity).
C3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024988Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternati [...]
Prss29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024993Serine protease 29; Involved in embryo hatching and implantation. Belongs to the peptidase S1 family.
Tpsg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000024999Tryptase gamma heavy chain; Belongs to the peptidase S1 family. Tryptase subfamily.
St6gal2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025000Beta-galactoside alpha-2,6-sialyltransferase 2; Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. Has alpha-2,6- sialyltransferase act [...]
Tekt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025002Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility.
Sox8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025003Transcription factor SOX-8; May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.
Adgre4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025004Adhesion G protein-coupled receptor E4; May mediate the cellular interaction between myeloid cells and B-cells; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled rece [...]
Nme4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025007Nucleoside diphosphate kinase, mitochondrial; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-p [...]
Tmem8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025010Post-GPI attachment to proteins factor 6; Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 [...]
Mrpl28 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002501439S ribosomal protein L28, mitochondrial; Belongs to the bacterial ribosomal protein bL28 family.
Arhgdig protein networkhttps://string-db.org/network/10090.ENSMUSP00000025019Rho GDP-dissociation inhibitor 3; Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, bo [...]
Rgs11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025020Regulator of G-protein signaling 11; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
Dusp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025025Dual specificity protein phosphatase 1; Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell c [...]
Cuta protein networkhttps://string-db.org/network/10090.ENSMUSP00000025027Protein CutA.
Kdm4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000025036Lysine-specific demethylase 4B; Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys- [...]
Uqcc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025045Ubiquinol-cytochrome-c reductase complex assembly factor 2; Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b- [...]
Ip6k3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025046Inositol hexakisphosphate kinase 3; Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 (B [...]
Acsbg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025048Acyl-CoA synthetase bubblegum family member 3.
Nudt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025050Diphosphoinositol polyphosphate phosphohydrolase 1; Cleaves a beta-phosphate from the diphosphate groups in PP- InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol t [...]
Mllt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025053Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, Drosophila) translocated to, 1.
Spdef protein networkhttps://string-db.org/network/10090.ENSMUSP00000025054SAM pointed domain-containing Ets transcription factor; May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. [...]
Anks1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025058Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction [...]
Clpsl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025061Colipase-like protein 2.
Clps protein networkhttps://string-db.org/network/10090.ENSMUSP00000025062Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an i [...]
Pdzph1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025064PDZ and pleckstrin homology domains 1.
Nudt12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025065Peroxisomal NADH pyrophosphatase NUDT12; Hydrolyzes NAD(P)H to NMNH and AMP (2',5'-ADP), and diadenosine diphosphate to AMP. Has also activity towards NAD(P)(+), ADP-ribose and diadenosine tripho [...]
Bambi protein networkhttps://string-db.org/network/10090.ENSMUSP00000025075BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling.
Lyzl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025076Lysozyme-like protein 1.
Mtpap protein networkhttps://string-db.org/network/10090.ENSMUSP00000025077Poly(A) RNA polymerase, mitochondrial; Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). [...]
Map3k8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025078Mitogen-activated protein kinase kinase kinase 8; Required for lipopolysaccharide (LPS)-induced, TLR4-mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for productio [...]
Zeb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025081Zinc finger E-box-binding homeobox 1; Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other t [...]
Kif5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000025083Kinesin-1 heavy chain; Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. May be involved in the mechanisms of growth arrest induced by exposure to DNA-da [...]
Map4k3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025089Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway (By similarity). Belongs to [...]
Tmem178 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025092Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the i [...]
Thumpd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025093THUMP domain-containing protein 2; Belongs to the methyltransferase superfamily.
Dync2li1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025101Cytoplasmic dynein 2 light intermediate chain 1; Required for correct intraflagellar transport (IFT), the bi- directional movement of particles required for the assembly, maintenance and function [...]
Polr2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000025106DNA-directed RNA polymerase II subunit RPB4; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
Sap130 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025109Histone deacetylase complex subunit SAP130; Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interacti [...]
Syt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025110Synaptotagmin-4; Synaptotagmin family member which does not bind Ca(2+). Plays a role in dendrite formation by melanocytes (By similarity).
Mapre2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025127Microtubule-associated protein RP/EB family member 2; May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a [...]
Thoc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025137THO complex subunit 1; Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing a [...]
Esco1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025142N-acetyltransferase ESCO1; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromati [...]
Tapbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000025161Tapasin; Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
Pfdn6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025163Prefoldin subunit 6; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which the [...]
Cdh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025166Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the [...]
Wdr46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025170WD repeat-containing protein 46; Scaffold component of the nucleolar structure. Required for localization of DDX21 and NCL to the granular compartment of the nucleolus.
Vps52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025178Vacuolar protein sorting-associated protein 52 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TG [...]
H2-K1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025181H-2 class I histocompatibility antigen, K-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family.
Ring1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025183E3 ubiquitin-protein ligase RING1; Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code [...]
Slc39a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025186Zinc transporter SLC39A7; Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol. Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subf [...]
H2-Oa protein networkhttps://string-db.org/network/10090.ENSMUSP00000025192Histocompatibility 2, O region alpha locus; Belongs to the MHC class II family.
Brd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025193Bromodomain-containing protein 2; Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. [...]
Psmb8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025196Proteasome subunit beta type-8; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the lea [...]
Tap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025197Antigen peptide transporter 2; Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold [...]
Btnl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025198Butyrophilin-like protein 2; Negative regulator of T-cell proliferation. Belongs to the immunoglobulin superfamily. BTN/MOG family.
Pfdn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025204Prefoldin subunit 1; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which the [...]
Dnajc18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025208DnaJ homolog subfamily C member 18.
Spata24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025209Spermatogenesis-associated protein 24; Binds DNA with high affinity but does not bind to TATA boxes. Synergises with GMNN and TBP in activation of TATA box-containing promoters and with GMNN and [...]
Mzb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025211Marginal zone B- and B1-cell-specific protein; Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular [...]
Slc23a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025212Solute carrier family 23 member 1; Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate (By similarity); Belongs to the xa [...]
Sil1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025215Nucleotide exchange factor SIL1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5 (By [...]
Hspa9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025217Stress-70 protein, mitochondrial; Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly protein [...]
Etf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025218Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA (By similarity). Compo [...]
Cyp21a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025223Steroid 21-hydroxylase; Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids.
Gfra3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025224GDNF family receptor alpha-3; Receptor for the glial cell line-derived neurotrophic factor, artemin. Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine k [...]
Cfb protein networkhttps://string-db.org/network/10090.ENSMUSP00000025229Complement factor B Ba fragment; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines [...]
C2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025230Complement C2a fragment; Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, th [...]
Epb41l4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000025234Band 4.1-like protein 4A.
Stard4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025236StAR-related lipid transfer protein 4; Involved in the intracellular transport of cholesterol. Binds cholesterol or other sterols.
Tslp protein networkhttps://string-db.org/network/10090.ENSMUSP00000025237Thymic stromal lymphopoietin; Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce [...]
Bin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025239Myc box-dependent-interacting protein 1; Is a key player in the control of plasma membrane curvature, and membrane shaping and remodeling. Required in muscle cells for the formation of T-tubules, [...]
Ercc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025241General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, whic [...]
Iws1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025243Protein IWS1 homolog; Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA [...]
Apom protein networkhttps://string-db.org/network/10090.ENSMUSP00000025249Apolipoprotein M; Probably involved in lipid transport. Can bind sphingosine-1- phosphate, myristic acid, palmitic acid and stearic acid, retinol, all- trans-retinoic acid and 9-cis-retinoic acid [...]
Bag6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025250Large proline-rich protein BAG6; ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein [...]
Prrc2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000025253Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing.
Lims2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025254LIM and senescent cell antigen-like-containing domain protein 2; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface re [...]
Ltb protein networkhttps://string-db.org/network/10090.ENSMUSP00000025262Lymphotoxin-beta; Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the [...]
Tnf protein networkhttps://string-db.org/network/10090.ENSMUSP00000025263Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is p [...]
Wdr33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025264pre-mRNA 3' end processing protein WDR33; Essential for both cleavage and polyadenylation of pre-mRNA 3' ends; Belongs to the WD repeat WDR33 family.
Lta protein networkhttps://string-db.org/network/10090.ENSMUSP00000025266Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lym [...]
Riok3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025270Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA vir [...]
Pou5f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025271POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression [...]
Psors1c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025273Psoriasis susceptibility 1 candidate gene 2 protein homolog.
Rmc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025276Regulator of MON1-CCZ1 complex; Componement of the CCZ1-MON1 RAB7A guanine exchange factor (GEF). Acts as a positive regulator of CCZ1-MON1A/B function necessary for endosomal/autophagic flux and [...]
Mrpl27 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002527839S ribosomal protein L27, mitochondrial; Belongs to the bacterial ribosomal protein bL27 family.
Npc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025279NPC intracellular cholesterol transporter 1; Intracellular cholesterol transporter which acts in concert with NPC2 and plays an important role in the egress of cholesterol from the endosomal/lyso [...]
Zfp521 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025288Zinc finger protein 521; Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartmen [...]
Impact protein networkhttps://string-db.org/network/10090.ENSMUSP00000025290Protein IMPACT; Translational regulator that ensures constant high levels of translation upon a variety of stress conditions, such as amino acid starvation, UV-C irradiation, proteasome inhibitor [...]
Dhx16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025292DEAH (Asp-Glu-Ala-His) box polypeptide 16.
Spry4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025295Protein sprouty homolog 4; Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs [...]
Mrps18b protein networkhttps://string-db.org/network/10090.ENSMUSP0000002530528S ribosomal protein S18b, mitochondrial.
Pcdh12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025311Protocadherin-12, secreted form; Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions. Acts as a regulator of cell migration, probabl [...]
Dele1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025314DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation.
Rpp21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025319Ribonuclease P protein subunit p21; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNa [...]
H2-M10.1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025322Histocompatibility 2, M region locus 10.1; Belongs to the MHC class I family.
Diaph1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025337Protein diaphanous homolog 1; Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers. Binds to the barbed end of the actin [...]
Gabbr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025338Gamma-aminobutyric acid type B receptor subunit 1; Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABB [...]
Myot protein networkhttps://string-db.org/network/10090.ENSMUSP00000025349Myotilin; Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells (By similarity).
Dcp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025350m7GpppN-mRNA hydrolase; Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphoryl [...]
Mal2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025356Protein MAL2; Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order [...]
Ap3s1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025357AP-3 complex subunit sigma-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral str [...]
Lvrn protein networkhttps://string-db.org/network/10090.ENSMUSP00000025358Aminopeptidase Q; Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo-maternal interface. On synthetic substrates it shows a ma [...]
Hbegf protein networkhttps://string-db.org/network/10090.ENSMUSP00000025363Proheparin-binding EGF-like growth factor; Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smoot [...]
Yipf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025364Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi; Belongs to the YIP1 family.
Pou4f3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025374POU domain, class 4, transcription factor 3; Acts as a transcriptional activator. Acts by binding to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of i [...]
Ppp2r2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000025377Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the l [...]
Spink1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025381Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.
Hsd17b4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025385Peroxisomal multifunctional enzyme type 2; Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids. Catalyzes the formation of 3-ketoacyl-CoA intermediates from both [...]
Ftmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000025388Ferritin, mitochondrial; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited [...]
Dynap protein networkhttps://string-db.org/network/10090.ENSMUSP00000025390Dynactin-associated protein.
Smad4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025393Mothers against decapentaplegic homolog 4; Common SMAD (co-SMAD) is the coactivator and mediator of signal transduction by TGF-beta (transforming growth factor). Component of the heterotrimeric S [...]
Sec11c protein networkhttps://string-db.org/network/10090.ENSMUSP00000025394Signal peptidase complex catalytic subunit SEC11C; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen [...]
Grp protein networkhttps://string-db.org/network/10090.ENSMUSP00000025395Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch [...]
Rax protein networkhttps://string-db.org/network/10090.ENSMUSP00000025396Retinal homeobox protein Rx; Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor cons [...]
Cplx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025397Complexin-4; Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion. Required for the maintenance of synaptic ultrastructure in the adult retina. Positively regulates syn [...]
Pmaip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025399Phorbol-12-myristate-13-acetate-induced protein 1; Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. [...]
Gnal protein networkhttps://string-db.org/network/10090.ENSMUSP00000025402Guanine nucleotide-binding protein G(olf) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(o [...]
Impa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025403Inositol monophosphatase 2; Can use myo-inositol monophosphates, scylloinositol 1,4- diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. Has been implicated as the [...]
Cidea protein networkhttps://string-db.org/network/10090.ENSMUSP00000025404Cell death activator CIDE-A; Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes d [...]
Srfbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025406Serum response factor-binding protein 1; May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of S [...]
Afg3l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025408AFG3-like protein 2; ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, li [...]
Lox protein networkhttps://string-db.org/network/10090.ENSMUSP00000025409Protein-lysine 6-oxidase, short form; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expr [...]
Prelid3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000025411PRELI domain containing protein 3A; In vitro, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the m [...]
Psmg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025418Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 prot [...]
Ppic protein networkhttps://string-db.org/network/10090.ENSMUSP00000025419Peptidyl-prolyl cis-trans isomerase C; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.
Seh1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000025421Nucleoporin SEH1; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex i [...]
Cep192 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025425Centrosomal protein 192.
Setbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025430SET-binding protein.
Me2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025439NAD-dependent malic enzyme, mitochondrial.
Cxxc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025444CXXC-type zinc finger protein 1; Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.
Rbfa protein networkhttps://string-db.org/network/10090.ENSMUSP00000025462Putative ribosome-binding factor A, mitochondrial.
Pde6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000025468Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; This protein participates in processes of transmission and amplification of the visual signal.
Il17b protein networkhttps://string-db.org/network/10090.ENSMUSP00000025471Interleukin-17B; Stimulates the release of tumor necrosis factor alpha and IL- 1-beta from the monocytic cell line THP-1; Belongs to the IL-17 family.
Pcyox1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000025472Prenylcysteine oxidase-like; Probable oxidoreductase.
Napg protein networkhttps://string-db.org/network/10090.ENSMUSP00000025474Gamma-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
St8sia3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025477Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase; Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto the terminal sialic acid of an acceptor through alp [...]
Atp8b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025482Phospholipid-transporting ATPase IC; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the [...]
Lmnb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025486Lamin-B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope an [...]
C330018D20Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000025488Glutaredoxin-like protein C5orf63 homolog; Belongs to the glutaredoxin family. YDR286C subfamily.
Prrc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025490Protein PRRC1.
Fbn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025497Fibrillin-2 C-terminal peptide; [Fibrillin-2]: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in el [...]
Slc27a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025500Solute carrier family 27 (fatty acid transporter), member 6.
Isoc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025503Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family.
Dctn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025505Dynactin subunit 4; Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles [...]
Rbm22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025506Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop [...]
Tmx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025515Protein disulfide-isomerase TMX3; Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase (By similarity).
Slc6a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025520Sodium-dependent proline transporter; Terminates the action of proline by its high affinity sodium- dependent reuptake into presynaptic terminals; Belongs to the sodium:neurotransmitter symporter [...]
Cdx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025521Homeobox protein CDX-1; Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 pr [...]
Pdgfrb protein networkhttps://string-db.org/network/10090.ENSMUSP00000025522Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays [...]
Gnaq protein networkhttps://string-db.org/network/10090.ENSMUSP00000025541Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regul [...]
Psat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025542Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
Timm21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025547Mitochondrial import inner membrane translocase subunit Tim21; Participates in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane. Also required for [...]
Scgb1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025554Uteroglobin; Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2; Belongs to the secretoglobin family.
Anxa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025561Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a [...]
Incenp protein networkhttps://string-db.org/network/10090.ENSMUSP00000025562Inner centromere protein; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ens [...]
Fads2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025567Acyl-CoA 6-desaturase; Acts as a fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 6 of the fatty acyl chain. Involved in biosynthesis of highly unsaturated fatty [...]
Tmem138 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025568Transmembrane protein 138; Required for ciliogenesis.
Sdhaf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025570Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) [...]
Cd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025571T-cell surface glycoprotein CD5; May act as a receptor in regulating T-cell proliferation.
Ms4a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025574Membrane-spanning 4-domains, subfamily A, member 7.
Ms4a4d protein networkhttps://string-db.org/network/10090.ENSMUSP00000025581Membrane-spanning 4-domains subfamily A member 4D; May be involved in signal transduction as a component of a multimeric receptor complex.
Ms4a6d protein networkhttps://string-db.org/network/10090.ENSMUSP00000025582Membrane-spanning 4-domains subfamily A member 6D; May be involved in signal transduction as a component of a multimeric receptor complex.
Cblif protein networkhttps://string-db.org/network/10090.ENSMUSP00000025585Cobalamin binding intrinsic factor; Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via recepto [...]
Osbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000025590Oxysterol-binding protein 1; Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphat [...]
Keg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025598Glycine N-acyltransferase-like protein Keg1; Acyltransferase which transfers the acyl group to the N- terminus of glycine. Can conjugate a multitude of substrates to form a variety of N-acylglyci [...]
Lpxn protein networkhttps://string-db.org/network/10090.ENSMUSP00000025601Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negati [...]
Gna14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025602Guanine nucleotide-binding protein subunit alpha-14; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs [...]
Rfk protein networkhttps://string-db.org/network/10090.ENSMUSP00000025617Riboflavin kinase; Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reac [...]
Pcsk5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025618Proprotein convertase subtilisin/kexin type 5; Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely fu [...]
Ostf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025631Osteoclast-stimulating factor 1; Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.
Carnmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025632Carnosine N-methyltransferase; N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine ( [...]
Ms4a8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000025636Membrane-spanning 4-domains subfamily A member 8; May be involved in signal transduction as a component of a multimeric receptor complex.
Ccdc86 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025639Coiled-coil domain-containing protein 86.
Zp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025641Processed zona pellucida sperm-binding protein 1; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and [...]
Tmem132a protein networkhttps://string-db.org/network/10090.ENSMUSP00000025645Transmembrane protein 132A; May play a role in embryonic and postnatal development of the brain. Increased resistance to cell death induced by serum starvation in cultured cells. Regulates cAMP-i [...]
Slc15a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025646Solute carrier family 15 member 3; Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides (By similarity).
Pga5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025647Pepsin A-5; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent (By similarity). May play a role as [...]
Ddb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025649DNA damage-binding protein 1; Required for DNA repair. Binds to DDB2 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damag [...]
Aldh1a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025656Aldehyde dehydrogenase, cytosolic 1; Can oxidize benzaldehyde, propionaldehyde and acetaldehyde (By similarity). No detectable activity with retinal.
Slc22a19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025666Solute carrier family 22 member 19; Sodium-independent organic anion transporter which shows high specificity for estrone sulfate, dehydroepiandrosterone sulfate, and the mycotoxin ochratoxin A ( [...]
Atl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025668Atlastin-3; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular netw [...]
Naa40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025675N-alpha-acetyltransferase 40; N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A (By similarity). In contrast to other N-alpha- [...]
Otub1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025679Ubiquitin thioesterase OTUB1; Hydrolase that can specifically remove compared to 'Lys-48'- linked conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein [...]
Lipf protein networkhttps://string-db.org/network/10090.ENSMUSP00000025680Gastric triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.
Cdc42bpg protein networkhttps://string-db.org/network/10090.ENSMUSP00000025681Serine/threonine-protein kinase MRCK gamma; May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, throu [...]
Lipn protein networkhttps://string-db.org/network/10090.ENSMUSP00000025682Lipase member N; Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers (By [...]
Ehd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025684EH domain-containing protein 1; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes (By sim [...]
Lipm protein networkhttps://string-db.org/network/10090.ENSMUSP00000025685Lipase member M; Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers (By [...]
Ankrd22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025686Ankyrin repeat domain-containing protein 22.
Fas protein networkhttps://string-db.org/network/10090.ENSMUSP00000025691Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling comp [...]
Ppp2r5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000025695Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform; As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate s [...]
Ak3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025696GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotrans [...]
Snx15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025702Sorting nexin-15; May be involved in several stages of intracellular trafficking. Overexpression of SNX15 disrupts the normal trafficking of proteins from the plasma membrane to recycling endosom [...]
Cdca5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025704Sororin; Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chr [...]
Tnfrsf25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025706Tumor necrosis factor receptor superfamily, member 25.
Zfpl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025707Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with [...]
Vps51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025711Vacuolar protein sorting-associated protein 51 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TG [...]
Tm7sf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025713Delta(14)-sterol reductase TM7SF2; Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis; Belongs to the ERG4/ERG [...]
Rpp30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025714Ribonuclease P protein subunit p30; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclea [...]
Mlana protein networkhttps://string-db.org/network/10090.ENSMUSP00000025719Melan-A.
Il33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025724Interleukin-33(102-266); Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturat [...]
Trpd52l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025727Tumor protein D52-like 3.
Frmd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025728FERM domain-containing protein 8; Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway. By acting on iRhoms, involve [...]
Tnks2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025729Poly [ADP-ribose] polymerase tankyrase-2; Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of [...]
Slc25a45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025732Solute carrier family 25 member 45.
Uhrf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025739E3 ubiquitin-protein ligase UHRF2; E3 SUMO-, but not ubiquitin-, protein ligase for ZNF131 (By similarity). E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle net [...]
Rad9a protein networkhttps://string-db.org/network/10090.ENSMUSP00000025740Cell cycle checkpoint control protein RAD9A; Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon [...]
Mrpl21 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002574539S ribosomal protein L21, mitochondrial.
Rps6kb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025749Ribosomal protein S6 kinase beta-2; Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell prolife [...]
Ighmbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025751DNA-binding protein SMUBP-2; 5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of th [...]
Pola2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025752DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of D [...]
Dmrt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025755Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell [...]
Eif1ad protein networkhttps://string-db.org/network/10090.ENSMUSP00000025759Probable RNA-binding protein EIF1AD; Plays a role into cellular response to oxidative stress. Decreases cell proliferation (By similarity).
Chka protein networkhttps://string-db.org/network/10090.ENSMUSP00000025760Choline kinase alpha; Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidy [...]
Cabp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025761Calcium-binding protein 4; Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. [...]
Banf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025762Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chroma [...]
Cst6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025764Cystatin E/M.
Pold4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025773DNA polymerase delta subunit 4; As a component of the tetrameric DNA polymerase delta complex (Pol-delta4), plays a role in high fidelity genome replication and repair. Within this complex, incre [...]
Sf3b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025774Splicing factor 3b, subunit 2.
Gldc protein networkhttps://string-db.org/network/10090.ENSMUSP00000025778Glycine dehydrogenase (decarboxylating), mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its p [...]
Cdk2ap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025779Cyclin-dependent kinase 2-associated protein 2; Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs [...]
Pacs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025786Phosphofurin acidic cluster sorting protein 1; Coat protein that is involved in the localization of trans- Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. Contro [...]
Mbl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025797Mannose-binding protein C; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complemen [...]
Pip5k1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000025800Phosphatidylinositol 4-phosphate 5-kinase type-1 beta; Participates in the biosynthesis of phosphatidylinositol 4,5- bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contr [...]
Nudt8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025802Nucleoside diphosphate-linked moiety X motif 8; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family.
Dkk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025803Dickkopf-related protein 1; Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes inte [...]
Rab1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000025804Ras-related protein Rab-1B; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle bet [...]
Cnih2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025805Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modula [...]
Doc2g protein networkhttps://string-db.org/network/10090.ENSMUSP00000025806Double C2-like domain-containing protein gamma; May be involved in regulation of vesicular trafficking. In vitro, does not bind calcium and phospholipids.
Yif1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000025811Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi.
Cbwd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025815COBW domain-containing protein 1.
Rce1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025823CAAX prenyl protease 2; Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K- Ras, N-Ras, H-Ras, RAP1B and G-gamma-1 (By s [...]
Minpp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025827Multiple inositol polyphosphate phosphatase 1; Acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycer [...]
Apba1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025830Amyloid-beta A4 precursor protein-binding family A member 1; Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic mac [...]
Dock8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025831Dedicator of cytokinesis protein 8; Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, require [...]
Papss2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025833Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2; Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. T [...]
Peli3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025834E3 ubiquitin-protein ligase pellino homolog 3; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL- 1 signaling pathwa [...]
Cpt1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000025835Carnitine O-palmitoyltransferase 1, liver isoform; Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake [...]
Mrpl11 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002583639S ribosomal protein L11, mitochondrial; Belongs to the universal ribosomal protein uL11 family.
Tesmin protein networkhttps://string-db.org/network/10090.ENSMUSP00000025840Tesmin; May have a role in spermatogenesis.
Ctsw protein networkhttps://string-db.org/network/10090.ENSMUSP00000025844Cathepsin W; May have a specific function in the mechanism or regulation of T-cell cytolytic activity; Belongs to the peptidase C1 family.
Fibp protein networkhttps://string-db.org/network/10090.ENSMUSP00000025847Acidic fibroblast growth factor intracellular-binding protein; May be involved in mitogenic function of FGF1 (By similarity). May mediate with IER2 FGF-signaling in the establishment of lateralit [...]
Fosl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025850Fos-related antigen 1; Belongs to the bZIP family. Fos subfamily.
Dpp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025851Dipeptidyl peptidase 3; Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin. Also cleaves Arg-Arg- beta-naphthylamide (in vitro); Belongs to the pept [...]
Lrp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025856Low-density lipoprotein receptor-related protein 5; Acts as a coreceptor with members of the frizzled family of seven-transmembrane spanning receptors to transduce signal by Wnt proteins. Activat [...]
Ovol1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025861Putative transcription factor Ovo-like 1; Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital s [...]
Smarca2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025862Probable global transcription activator SNF2L2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of [...]
Rnaseh2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000025864Ribonuclease H2 subunit C; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the rem [...]
Rela protein networkhttps://string-db.org/network/10090.ENSMUSP00000025867Transcription factor p65; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a v [...]
4430402I18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000025872Spermatogenesis associated 6-like protein; Belongs to the SPATA6 family.
Slc1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025875Excitatory amino acid transporter 3; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cyst [...]
Znrd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025885Protein ZNRD2; Might play a role in mitosis. Could be a centromere- associated protein. Antigenic molecule. May induce anti-centromere antibodies.
Capn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025891Calpain-1 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
Arl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025893ADP-ribosylation factor-like protein 2; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleoti [...]
Map4k2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025897Mitogen-activated protein kinase kinase kinase kinase 2; Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Acts as a MAPK kinase [...]
Rps6ka4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025903Ribosomal protein S6 kinase alpha-4; Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the reg [...]
Prdx5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025904Peroxiredoxin-5, mitochondrial; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell pr [...]
Esrra protein networkhttps://string-db.org/network/10090.ENSMUSP00000025906Steroid hormone receptor ERR1; Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase [...]
Kcnk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025908Potassium channel subfamily K member 4; Voltage-insensitive potassium channel. Channel opening is triggered by mechanical forces that deform the membrane. Channel opening is triggered by raising [...]
Bad protein networkhttps://string-db.org/network/10090.ENSMUSP00000025910Bcl2-associated agonist of cell death; Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins [...]
Plcb3 protein networkhttps://string-db.org/network/10090.ENSMUSP000000259121-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activ [...]
Vegfb protein networkhttps://string-db.org/network/10090.ENSMUSP00000025914Vascular endothelial growth factor B; Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. V [...]
Stip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025918Stress-induced-phosphoprotein 1; Acts as a co-chaperone for HSP90AA1. Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90.
Spindoc protein networkhttps://string-db.org/network/10090.ENSMUSP00000025924Spindlin interactor and repressor of chromatin-binding protein; Negatively regulates the transcriptional activator activity of SPIN1 via inhibition of its histone methyl-binding ability. Represse [...]
Plaat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025925Phospholipase A and acyltransferase 3; Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2), catalyzing the calcium-independent release of [...]
Plaat5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025929Phospholipase A and acyltransferase 5; Exhibits both phospholipase A1/2 and acyltransferase activities (By similarity). Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calciu [...]
Smc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025930Structural maintenance of chromosomes protein 3; Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous [...]
Shoc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025932Leucine-rich repeat protein SHOC-2; Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, [...]
Tectb protein networkhttps://string-db.org/network/10090.ENSMUSP00000025936Beta-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepith [...]
C1qtnf9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025940Complement C1q and tumor necrosis factor-related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways.
Hhex protein networkhttps://string-db.org/network/10090.ENSMUSP00000025944Hematopoietically-expressed homeobox protein Hhex; Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. May play a role in hematopoietic differentiation. Establishe [...]
Cyp26a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025946Cytochrome P450 26A1; A cytochrome P450 monooxygenase involved in the metabolism of all-trans retinoic acid (atRA), a signaling molecule that binds to retinoic acid receptors and regulates gene t [...]
Rbp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025951Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans [...]
Eif3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000025955Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiatio [...]
Pde6c protein networkhttps://string-db.org/network/10090.ENSMUSP00000025956Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decre [...]
Fam45a protein networkhttps://string-db.org/network/10090.ENSMUSP00000025957DENN domain-containing protein 10; Guanine nucleotide exchange factor (GEF) regulating homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion, possibly t [...]
Prdx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025961Thioredoxin-dependent peroxide reductase, mitochondrial; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively [...]
Noc3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000025963Nucleolar complex protein 3 homolog; May be required for adipogenesis.
Hells protein networkhttps://string-db.org/network/10090.ENSMUSP00000025965Lymphocyte-specific helicase; Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenanc [...]
Cyp2c55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025966Cytochrome P450 2C55; Metabolizes arachidonic acid mainly to 19- hydroxyeicosatetraenoic acid (HETE); Belongs to the cytochrome P450 family.
Cyp2c39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025968Cytochrome P450 2C39; Metabolizes arachidonic acid to produce 14,15-cis- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family.
Aldh18a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025979Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the [...]
Tctn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025981Tectonic-3; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. May be involved in apoptosis regulation (By similar [...]
Ccnj protein networkhttps://string-db.org/network/10090.ENSMUSP00000025983Cyclin-J.
Tll2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025986Tolloid-like protein 2; Protease which specifically processes pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral [...]
Slit1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025993Slit homolog 1 protein; Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural develop [...]
Smndc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025997Survival of motor neuron-related-splicing factor 30; Necessary for spliceosome assembly. Overexpression causes apoptosis (By similarity); Belongs to the SMN family.
Add3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000025999Gamma-adducin; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Plays a role in actin filament capping. Binds to calmodulin; Belongs to the aldol [...]
Trim8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026008Probable E3 ubiquitin-protein ligase TRIM8; Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1; Belongs to the TRIM/RBCC family.
Arl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026009ADP-ribosylation factor-like protein 3; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleoti [...]
Sfxn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026011Sideroflexin-2; Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria.
Cyp17a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026012Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for bo [...]
Maoa protein networkhttps://string-db.org/network/10090.ENSMUSP00000026013Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in th [...]
Efhc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026014EF-hand domain-containing family member C2.
Fundc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026016FUN14 domain-containing protein 1; Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control; Belongs to the FUN14 family.
Dusp21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026018Dual specificity phosphatase 21; Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine; [...]
Msr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026021Macrophage scavenger receptor types I and II; Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits [...]
Taf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026027Transcription initiation factor TFIID subunit 5; TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs compon [...]
Samt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026029Spermatogenesis-associated multipass transmembrane protein 4.
Pcgf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026032Polycomb group RING finger protein 6; Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprote [...]
Nr0b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026036Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulat [...]
Col17a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026045120 kDa linear IgA disease antigen homolog; May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.
Gsto1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026050Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione [...]
Casp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026062Caspase-7 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Overexpressio [...]
Vwa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026068Von Willebrand factor A domain-containing protein 2.
Trub1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026073Probable tRNA pseudouridine synthase 1; Pseudouridine synthase that catalyzes pseudouridylation of mRNAs. Mediates pseudouridylation of mRNAs with the consensus sequence 5'-GUUCNANNC-3', harborin [...]
Gfra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026076GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity).
Pnliprp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026081Pancreatic lipase-related protein 2; Lipase with broad substrate specificity. Can hydrolyze both phospholipids and galactolipids. Acts preferentially on monoglycerides, phospholipids and galactol [...]
Slc18a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026084Synaptic vesicular amine transporter; Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, seroton [...]
3110040N11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000026092UPF0235 protein C15orf40 homolog; Belongs to the UPF0235 family.
Btbd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026093BTB/POZ domain-containing protein 1; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of tar [...]
Bnc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026096Zinc finger protein basonuclin-1; Transcriptional activator. Likely specific for squamous epithelium and for the constituent keratinocytes at a stage either prior to or at the very beginning of t [...]
Gcgr protein networkhttps://string-db.org/network/10090.ENSMUSP00000026119Glucagon receptor; G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose produ [...]
Bhlhe22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026120Class E basic helix-loop-helix protein 22; Inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, pro [...]
Ppp1r27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026121Protein phosphatase 1 regulatory subunit 27; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
P4hb protein networkhttps://string-db.org/network/10090.ENSMUSP00000026122Protein disulfide-isomerase; This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves dis [...]
Alyref protein networkhttps://string-db.org/network/10090.ENSMUSP00000026125THO complex subunit 4; Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pat [...]
Ints4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026126Integrator complex subunit 4; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The [...]
Anapc11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026128Anaphase-promoting complex subunit 11; Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 [...]
Pcyt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026129Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP- ethanolamine (By similarity) [...]
Myadml2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026134Myeloid-associated differentiation marker-like protein 2; Belongs to the MAL family.
Aspscr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026135Tether containing UBX domain for GLUT4; Enhances VCP methylation catalyzed by VCPKMT (By similarity). Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence o [...]
Lrrc45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026139Leucine-rich repeat-containing protein 45; Component of the proteinaceous fiber-like linker between two centrioles, required for centrosome cohesion.
Maged1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026142Melanoma-associated antigen D1; Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apopto [...]
Dcxr protein networkhttps://string-db.org/network/10090.ENSMUSP00000026144L-xylulose reductase; Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metab [...]
Cbr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026148Carbonyl reductase [NADPH] 2; May function in the pulmonary metabolism of endogenous carbonyl compounds, such as aliphatic aldehydes and ketones derived from lipid peroxidation, 3-ketosteroids an [...]
Arhgap19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026150Rho GTPase-activating protein 19; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Zdhhc16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026154Palmitoyltransferase ZDHHC16; Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6. Required during embryonic heart development and cardiac function, possibly [...]
Rfng protein networkhttps://string-db.org/network/10090.ENSMUSP00000026156Beta-1,3-N-acetylglucosaminyltransferase radical fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of [...]
Cd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026159T-cell antigen CD7; Not yet known.
Sectm1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000026162Secreted and transmembrane protein 1A.
Ogfod3 protein networkhttps://string-db.org/network/10090.ENSMUSP000000261692-oxoglutarate and iron-dependent oxygenase domain-containing protein 3.
Ubtd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026170Ubiquitin domain-containing protein 1; May be involved in the regulation of cellular senescence through a positive feedback loop with TP53. Is a TP53 downstream target gene that increases the sta [...]
Ankrd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026172Ankyrin repeat domain-containing protein 2; Functions as a negative regulator of myocyte differentiation. May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate [...]
Wdr45b protein networkhttps://string-db.org/network/10090.ENSMUSP00000026173WD repeat domain phosphoinositide-interacting protein 3; Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged [...]
Fn3k protein networkhttps://string-db.org/network/10090.ENSMUSP00000026175Fructosamine-3-kinase; Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate. [...]
R3hcc1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000026188Coiled-coil domain-containing protein R3HCC1L.
Got1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026196Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the verte [...]
Abcc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026208Canalicular multispecific organic anion transporter 1; Mediates hepatobiliary excretion of numerous organic anions and conjugated organic anions such as methotrexate, 17beta-estradiol 17-glucosid [...]
Cpn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026210Carboxypeptidase N catalytic chain; Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into [...]
Cyp2c23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026211Cytochrome P450 2C44; A cytochrome P450 monooxygenase involved in polyunsaturated fatty acids (PUFAs) metabolism and signaling. Catalyzes preferentially the epoxidation of double bonds of PUFAs. [...]
Chuk protein networkhttps://string-db.org/network/10090.ENSMUSP00000026217Inhibitor of nuclear factor kappa-B kinase subunit alpha; Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammator [...]
Cwf19l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026218CWF19-like protein 1.
Scd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026220Acyl-CoA desaturase 3; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes th [...]
Scd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026221Acyl-CoA desaturase 2; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes th [...]
Ndufb8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026222NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not [...]
Sema4g protein networkhttps://string-db.org/network/10090.ENSMUSP00000026225Semaphorin-4G; Cell surface receptor for PLXNB2. May play a role in axon guidance; Belongs to the semaphorin family.
Twnk protein networkhttps://string-db.org/network/10090.ENSMUSP00000026227Twinkle protein, mitochondrial; Involved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function infered to be critical for lifetime main [...]
Tlx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026236T-cell leukemia homeobox protein 1; Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.
Poll protein networkhttps://string-db.org/network/10090.ENSMUSP00000026239DNA polymerase lambda; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) site [...]
Fgf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026241Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear an [...]
Oga protein networkhttps://string-db.org/network/10090.ENSMUSP00000026243Protein O-GlcNAcase; Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc [...]
Gbf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026254Golgi-specific brefeldin A-resistance factor 1.
Fbxl15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026256F-box/LRR-repeat protein 15; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal de [...]
Pitx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026259Pituitary homeobox 3; Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. In addition to its [...]
Hexa protein networkhttps://string-db.org/network/10090.ENSMUSP00000026262Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.
Bbs4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026265Bardet-Biedl syndrome 4 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is [...]
Parp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026267Protein mono-ADP-ribosyltransferase PARP6; Mono-ADP-ribosyltransferase that mediates mono-ADP- ribosylation of target proteins.
Limd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026269LIM domain-containing protein 1; Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate deter [...]
Sacm1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000026270Phosphatidylinositide phosphatase SAC1; Phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 4-phosphate (PtdIns(4)P) (By similarity [...]
Slc6a20b protein networkhttps://string-db.org/network/10090.ENSMUSP00000026273Sodium- and chloride-dependent transporter XTRP3B; Does not show transporter activity with a range of tested amino acids including proline, glutamine, glutamic acid, leucine, alanine, histidine, [...]
Lztfl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026274Leucine zipper transcription factor-like protein 1; Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the [...]
Zfhx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026284Zinc finger homeobox protein 4; May play a role in neural and muscle differentiation. May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Ribc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026288RIB43A-like with coiled-coils protein 1; Belongs to the RIB43A family.
Hsd17b10 protein networkhttps://string-db.org/network/10090.ENSMUSP000000262893-hydroxyacyl-CoA dehydrogenase type-2; Mitochondrial dehydrogenase that catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha- hydroxysteroid dehydrogenase activ [...]
Huwe1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026292E3 ubiquitin-protein ligase HUWE1; E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Regulates apoptosis by catalyzing the polyu [...]
Tsr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026295Pre-rRNA-processing protein TSR2 homolog; May be involved in 20S pre-rRNA processing.
Fgd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026296FYVE, RhoGEF and PH domain-containing protein 1; Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the ac [...]
Maged2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026302Melanoma antigen, family D, 2.
Dnase1l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026315Deoxyribonuclease gamma; Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends (By similarity). Can cleave chromatin to [...]
Sat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026318Diamine acetyltransferase 1; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)- acetylspermine > putrescine. This highly r [...]
Polr3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000026322DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Acot9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026324Acyl-coenzyme A thioesterase 9, mitochondrial; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the [...]
4933436I01Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000026325RIKEN cDNA 4933436I01 gene.
Prdx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026328Peroxiredoxin-4; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection agains [...]
Jph3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026357Junctophilin-3; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. [...]
Itgb8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026360Integrin beta-8; Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). Integrin alpha-V:beta-6 (ITG [...]
Padi3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026377Protein-arginine deiminase type-3; Catalyzes the deimination of arginine residues of proteins. Belongs to the protein arginine deiminase family.
Padi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026378Protein-arginine deiminase type-1; Catalyzes the deimination of arginine residues of proteins. Belongs to the protein arginine deiminase family.
Padi4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026381Protein-arginine deiminase type-4; Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem ce [...]
Gpr143 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026383G-protein coupled receptor 143; Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca(2+) influx into the cytoplasm, increases secretion of the neurotrophic factor SE [...]
Sbds protein networkhttps://string-db.org/network/10090.ENSMUSP00000026387Ribosome maturation protein SBDS; Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in t [...]
Rabgef1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026390Rab5 GDP/GTP exchange factor; Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. S [...]
Mettl7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000026398Methyltransferase-like protein 7B; Probable methyltransferase.
Bloc1s1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026405Biogenesis of lysosome-related organelles complex 1 subunit 1; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as plat [...]
Rdh5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026406Retinol dehydrogenase 5; Catalyzes the oxidation of cis-isomers of retinol, including 11-cis-, 9-cis-, and 13-cis-retinol in an NAD-dependent manner. Has no activity towards all-trans retinal (By [...]
Gdf11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026408Growth/differentiation factor 11; Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. May play critical roles in patterning bot [...]
Ormdl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026409ORM1-like protein 2; Negative regulator of sphingolipid synthesis.
Dnajc14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026410DnaJ homolog subfamily C member 14; Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface.
Mmp19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026411Matrix metalloproteinase-19; Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemo [...]
Dgka protein networkhttps://string-db.org/network/10090.ENSMUSP00000026414Diacylglycerol kinase alpha; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kin [...]
Cdk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026416Cyclin-dependent kinase 2; Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, N [...]
Rps26 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002642040S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.
Esyt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026427Extended synaptotagmin-1; Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates t [...]
Myl6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000026428Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium.
Chmp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026434Charged multivesicular body protein 6; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation [...]
Baiap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026436Brain-specific angiogenesis inhibitor 1-associated protein 2; Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganizat [...]
Fscn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026445Fascin-2; Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis. Important for maintaining functional hair-cell bundless in [...]
Faap100 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026448Fanconi anemia core complex-associated protein 100; Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core com [...]
Il23a protein networkhttps://string-db.org/network/10090.ENSMUSP00000026449Interleukin-23 subunit alpha; Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acu [...]
Pde6g protein networkhttps://string-db.org/network/10090.ENSMUSP00000026452Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector mol [...]
Mip protein networkhttps://string-db.org/network/10090.ENSMUSP00000026455Lens fiber major intrinsic protein; Water channel. Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the [...]
Atp5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000026459ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane w [...]
Prim1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026461DNA primase small subunit; Catalytic subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an es [...]
Nab2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026469NGFI-A-binding protein 2; Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability.
Shmt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026470Serine hydroxymethyltransferase, mitochondrial; Catalyzes the cleavage of serine to glycine accompanied with the production of 5,10-methylenetetrahydrofolate, an essential intermediate for purine [...]
Inhbc protein networkhttps://string-db.org/network/10090.ENSMUSP00000026472Inhibin beta C chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diver [...]
Gli1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026474Zinc finger protein GLI1; Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal development. Plays [...]
Ddit3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026475DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell [...]
Mbd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026476Methyl-CpG-binding domain protein 6; Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro) (By similarity).
Dctn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026479Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring micr [...]
Ttc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026480Tetratricopeptide repeat protein 4; May act as a co-chaperone for HSP90AB1 (By similarity). Belongs to the TTC4 family.
Katnal2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026486Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays; Belongs to [...]
Ier3ip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026487Immediate early response 3-interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus; Belongs [...]
Rnf165 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026494E3 ubiquitin-protein ligase RNF165; E3 ubiquitin-protein ligase that acts as a regulator of motor axon elongation. Required for efficient motor axon extension in the dorsal forelimb by enhancing [...]
Atp5a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026495ATP synthase subunit alpha, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane [...]
Crisp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026498Cysteine-rich secretory protein 1; This protein is supposed to help spermatozoa undergo functional maturation while they move from the testis to the ductus deferens.
Crisp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026499Cysteine-rich secretory protein 3; This protein is supposed to help spermatozoa undergo functional maturation while they move from the testis to the ductus deferens; Belongs to the CRISP family.
Avil protein networkhttps://string-db.org/network/10090.ENSMUSP00000026500Advillin; Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outg [...]
Clns1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000026506Methylosome subunit pICln; Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins (By similarity). Chaperone that regulates the assembly of spliceosomal U1, U2, U [...]
Paip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026520Polyadenylate-binding protein-interacting protein 1; Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is medi [...]
Paox protein networkhttps://string-db.org/network/10090.ENSMUSP00000026537Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can als [...]
Echs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026538Enoyl-CoA hydratase, mitochondrial; Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate (By similarity). Has high substrate speci [...]
Fuom protein networkhttps://string-db.org/network/10090.ENSMUSP00000026539Fucose mutarotase; Involved in the interconversion between alpha- and beta-L- fucoses. L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is [...]
Prap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026540Proline-rich acidic protein 1; May play an important role in maintaining normal growth homeostasis in epithelial cells.
Caly protein networkhttps://string-db.org/network/10090.ENSMUSP00000026541Neuron-specific vesicular protein calcyon; Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.
Tubgcp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026547Gamma-tubulin complex component 2; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Adgra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026548Adhesion G protein-coupled receptor A1; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Inpp5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000026550Inositol polyphosphate-5-phosphatase A.
Dpysl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026551Dihydropyrimidinase-related protein 4; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse a [...]
Cyp2e1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026552Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the [...]
Syce1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026553Synaptonemal complex central element protein 1; Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. R [...]
Odf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026555Outer dense fiber protein 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maint [...]
Bet1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000026557BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity).
Ric8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000026558Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for fre [...]
Sirt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026559NAD-dependent protein deacetylase sirtuin-3; NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include [...]
Psmd13 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002656026S proteasome non-ATPase regulatory subunit 13; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a [...]
Cox8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000026561Cytochrome c oxidase subunit 8B, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The re [...]
Ifitm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026562Interferon-induced transmembrane protein 5; Required for normal bone mineralization.
Ifitm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026565Interferon-induced transmembrane protein 3; IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral f [...]
Ptdss2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026568Phosphatidylserine synthase 2; Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is spe [...]
Drd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026569D(4) dopamine receptor; Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by [...]
Irf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026571Interferon regulatory factor 7; Key transcriptional regulator of type I interferon (IFN)- dependent immune responses and plays a critical role in the innate immune response against DNA and RNA vi [...]
Hras protein networkhttps://string-db.org/network/10090.ENSMUSP00000026572GTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
Lmntd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026573Lamin tail domain-containing protein 2.
Taldo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026576Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Eps8l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026577Epidermal growth factor receptor kinase substrate 8-like protein 2; Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton (By [...]
Tmem80 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026578Transmembrane protein 80.
Pidd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026580P53-induced death domain-containing protein 1; Component of the DNA damage/stress response pathway that functions downstream of p53/TP53 and can either promote cell survival or apoptosis. Associa [...]
Tspan4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026585Tetraspanin-4; Belongs to the tetraspanin (TM4SF) family.
Tmem192 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026595Transmembrane protein 192.
Apool protein networkhttps://string-db.org/network/10090.ENSMUSP00000026599MICOS complex subunit Mic27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner mem [...]
Satl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026601Spermidine/spermine N(1)-acetyltransferase-like protein 1; Belongs to the acetyltransferase family.
Chm protein networkhttps://string-db.org/network/10090.ENSMUSP00000026607Rab proteins geranylgeranyltransferase component A 1; Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate p [...]
Crcp protein networkhttps://string-db.org/network/10090.ENSMUSP00000026608DNA-directed RNA polymerase III subunit RPC9; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripher [...]
Gusb protein networkhttps://string-db.org/network/10090.ENSMUSP00000026613Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates.
Phkg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026617Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen b [...]
Tm9sf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026624Transmembrane 9 superfamily member 2; In the intracellular compartments, may function as a channel or small molecule transporter; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
Clybl protein networkhttps://string-db.org/network/10090.ENSMUSP00000026625Citramalyl-CoA lyase, mitochondrial; Mitochondrial citramalyl-CoA lyase indirectly involved in the vitamin B12 metabolism. Converts citramalyl-CoA into acetyl-CoA and pyruvate in the C5-dicarboxy [...]
Farp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026635FERM, ARHGEF and pleckstrin domain-containing protein 1; Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disass [...]
Syngr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026649Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the f [...]
Tmc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026659Transmembrane channel-like protein 6; Probable ion channel.
Tk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026661Thymidine kinase, cytosolic.
Cbx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026662Chromobox protein homolog 2; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, includi [...]
Cbx8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026663Chromobox protein homolog 8; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, includi [...]
Cbx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026665E3 SUMO-protein ligase CBX4; E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly r [...]
Eif4a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026667Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent mu [...]
Nptx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026670Neuronal pentraxin-1; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitat [...]
Rptor protein networkhttps://string-db.org/network/10090.ENSMUSP00000026671Regulatory-associated protein of mTOR; Involved in the control of the mammalian target of rapamycin complex 1 (mTORC1) activity which regulates cell growth and survival, and autophagy in response [...]
Pde8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000026672High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May b [...]
Nat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026677Arylamine N-acetyltransferase 1; Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Isoniazid, 2-aminofluorene and anisidine are preferred substrates for NAT-1. No [...]
Tma16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026681Translation machinery-associated protein 16.
Zfp202 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026693Zinc finger protein 202.
Podxl protein networkhttps://string-db.org/network/10090.ENSMUSP00000026698Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neigh [...]
Mkln1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026699Muskelin; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcr [...]
Map3k7cl protein networkhttps://string-db.org/network/10090.ENSMUSP00000026700MAP3K7 C-terminal-like protein.
Bach1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026703Transcription regulator protein BACH1; Transcriptional regulator that acts as repressor or activator, depending on the context. Binds to NF-E2 DNA binding sites. Plays important roles in coordina [...]
Cct8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026704T-complex protein 1 subunit theta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC comple [...]
Usp16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026710Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactiva [...]
Hprt protein networkhttps://string-db.org/network/10090.ENSMUSP00000026723Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosyl [...]
Ccdc51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026735Mitochondrial potassium channel; Mitochondrial potassium channel located in the mitochondrial inner membrane. Together with ABCB8/MITOSUR, forms a protein complex localized in the mitochondria th [...]
Uqcrc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026743Cytochrome b-c1 complex subunit 1, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport [...]
Tmem89 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026744Transmembrane protein 89.
Cnksr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026750Connector enhancer of kinase suppressor of ras 2; May function as an adapter protein or regulator of Ras signaling pathways; Belongs to the CNKSR family.
Tmem47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026760Transmembrane protein 47; Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polym [...]
Alox5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026795Arachidonate 5-lipoxygenase; Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes. Belongs to the lipoxygenase family.
Wdr73 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026816WD repeat-containing protein 73; May play a role in the regulation of microtubule organization and dynamics.
Sec11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000026818Signal peptidase complex catalytic subunit SEC11A; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen [...]
Mettl26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026827Methyltransferase-like 26; Belongs to the UPF0585 family.
Mcrip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026828MAPK regulated corepressor interacting protein 2; Belongs to the MCRIP family.
Rhbdl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026831Rhomboid-related protein 1; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
Jmjd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026832JmjC domain-containing protein 8; Functions as a positive regulator of TNF-induced NF-kappaB signaling (By similarity). Regulates angiogenesis and cellular metabolism through interaction with PKM [...]
Wdr24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026833GATOR complex protein WDR24; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC [...]
Prps2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026839Ribose-phosphate pyrophosphokinase 2; Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis; Belongs to the ribose-phosphate pyrophosphokinase f [...]
Il6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026845Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-se [...]
Tyms protein networkhttps://string-db.org/network/10090.ENSMUSP00000026846Thymidylate synthase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
Plk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026858Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental cen [...]
Mfsd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026859Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily.
Sclt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026866Sodium channel and clathrin linker 1; Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity).
Gdap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026879Ganglioside-induced differentiation-associated protein 1; Regulates the mitochondrial network by promoting mitochondrial fission; Belongs to the GST superfamily.
Ly96 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026881Lymphocyte antigen 96; Binds bacterial lipopolysaccharide (LPS). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wa [...]
Itih5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026886Inter-alpha-trypsin inhibitor heavy chain H5; May act as a tumor suppressor; Belongs to the ITIH family.
Taf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026888Transcription initiation factor TFIID subunit 3; Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeri [...]
4930412O13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000026889RIKEN cDNA 4930412O13 gene.
Clec3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000026890Tetranectin; Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis (By similarity).
Exosc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026891Exosome complex exonuclease RRP42; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degr [...]
Tgm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026893Protein-glutamine gamma-glutamyltransferase 4; Associated with the mammalian reproductive process. Plays an important role in the formation of the seminal coagulum through the cross-linking of sp [...]
St8sia2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026896Alpha-2,8-sialyltransferase 8B; May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may [...]
Slco3a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026897Solute carrier organic anion transporter family member 3A1; Mediates the Na(+)-independent transport of organic anions. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltor [...]
Slc25a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026899Mitochondrial dicarboxylate carrier; Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane.
Rassf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026902Ras association domain-containing protein 3.
Klkb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026907Plasma kallikrein heavy chain; The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases [...]
Ccr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026911C-C chemokine receptor type 1; Receptor for a C-C type chemokine. Binds to MIP-1-alpha, RANTES, and less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the [...]
Ccdc7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000026912Coiled-coil domain-containing 7B.
Nrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026917Neuropilin-1; Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system (By [...]
Nudt5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026927ADP-sugar pyrophosphatase; Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate (By similarity). In abs [...]
Iscu protein networkhttps://string-db.org/network/10090.ENSMUSP00000026937Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mi [...]
Pramel7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026957Preferentially expressed antigen in melanoma-like protein 7; Promotes maintenance and self-renewal of pluripotent embryonic stem cells (ESCs), downstream of LIF/STAT3. Maintains the pluripotency [...]
Fam20c protein networkhttps://string-db.org/network/10090.ENSMUSP00000026972Extracellular serine/threonine protein kinase FAM20C; Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in bio [...]
Prkar1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000026973cAMP-dependent protein kinase type I-beta regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
Dnaaf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026975Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and out [...]
Get4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026976Golgi to ER traffic protein 4 homolog; As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches- containing proteins in a soluble [...]
Xiap protein networkhttps://string-db.org/network/10090.ENSMUSP00000026978E3 ubiquitin-protein ligase XIAP; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic k [...]
Cplx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026985Complexin-2; Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of [...]
Higd2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000026986HIG1 domain family member 2A; Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of ox [...]
Nop16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026987Nucleolar protein 16.
Arl10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026988ADP-ribosylation factor-like protein 10; Belongs to the small GTPase superfamily. Arf family.
4833439L19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000026989Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth (By similarity).
Thoc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026990THO complex subunit 3; Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcript [...]
Tspan17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026993Tetraspanin-17; Regulates ADAM10 maturation.
Unc5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000026994Netrin receptor UNC5A; Receptor for netrin required for axon guidance. Functions in the netrin signaling pathway and promotes neurite outgrowth in response to NTN1. Mediates axon repulsion of neu [...]
Uimc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026997BRCA1-A complex subunit RAP80; Ubiquitin-binding protein. Specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63' [...]
Smad7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000026999Mothers against decapentaplegic homolog 7; Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming g [...]
Casp12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027009Caspase-12; Involved in the activation cascade of caspases responsible for apoptosis execution; Belongs to the peptidase C14A family.
Casp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027012Caspase-4 subunit p10; Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non- canonical activators, such as U [...]
Casp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027015Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defen [...]
Gria4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027020Glutamate receptor 4; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate [...]
Cwf19l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027027CWF19-like protein 2.
Rp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027032Oxygen-regulated protein 1; Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors. Required for the differentiation of photorecepto [...]
Sox17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027035Transcription factor SOX-17; Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regu [...]
Lypla1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027036Acyl-protein thioesterase 1; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low l [...]
Rb1cc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027040RB1-inducible coiled-coil protein 1; Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the format [...]
Ppp1r42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027049Protein phosphatase 1 regulatory subunit 42; Regulates phosphatase activity of protein phosphatase 1 (PP1) complexes in the testis.
Cops5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027050COP9 signalosome complex subunit 5; Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an esse [...]
Rdh10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027053Retinol dehydrogenase 10; Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol [...]
Prex2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027056Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free [...]
Tfap2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000027059Transcription factor AP-2-beta; Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors [...]
Il17a protein networkhttps://string-db.org/network/10090.ENSMUSP00000027061Interleukin-17A; Ligand for IL17RA. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (By similarity). Involved in inducing stromal c [...]
Msc protein networkhttps://string-db.org/network/10090.ENSMUSP00000027062Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes.
Tmem14a protein networkhttps://string-db.org/network/10090.ENSMUSP00000027064Transmembrane protein 14A; Inhibits apoptosis via negative regulation of the mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; Belongs to the TMEM14 family.
Eya1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027066Eyes absent homolog 1; Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Ty [...]
Gsta3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027067Glutathione S-transferase A3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This GST has a high catalytic activity for aflatoxin B1-8, [...]
Tram1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027068Translocating chain-associated membrane protein 1; Stimulatory or required for the translocation of secretory proteins across the ER membrane; Belongs to the TRAM family.
Lactb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027071Endoribonuclease LACTB2; Endoribonuclease; cleaves preferentially 3' to purine- pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no ac [...]
Crygf protein networkhttps://string-db.org/network/10090.ENSMUSP00000027082Gamma-crystallin F; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family.
Pth2r protein networkhttps://string-db.org/network/10090.ENSMUSP00000027083Parathyroid hormone 2 receptor; This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsi [...]
Crygb protein networkhttps://string-db.org/network/10090.ENSMUSP00000027090Gamma-crystallin B; Crystallins are the dominant structural components of the vertebrate eye lens.
Fastkd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027103FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consis [...]
Ndufs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027111NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal [...]
Maip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027114m-AAA protease-interacting protein 1, mitochondrial; Promotes sorting of SMDT1/EMRE in mitochondria by ensuring its maturation. Interacts with the transit peptide region of SMDT1/EMRE precursor p [...]
Rftn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027121Raftlin-2; Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subseque [...]
Hspd1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002712360 kDa heat shock protein, mitochondrial; Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported prote [...]
Coq10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000027125Coenzyme Q-binding protein COQ10 homolog B, mitochondrial; Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 fro [...]
Sf3b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027127Splicing factor 3B subunit 1; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U [...]
Ccdc150 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027128Coiled-coil domain-containing protein 150.
Slc39a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027131Zinc transporter ZIP10; May act as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family.
Slc40a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027137Solute carrier family 40 member 1; May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the pr [...]
Wdr75 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027139WD repeat-containing protein 75; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I.
Cps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027144Carbamoyl-phosphate synthase [ammonia], mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.
Ikzf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027146Zinc finger protein Helios; Associates with Ikaros at centromeric heterochromatin.
Myl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027151Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.
Acadl protein networkhttps://string-db.org/network/10090.ENSMUSP00000027153Long-chain specific acyl-CoA dehydrogenase, mitochondrial; Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty aci [...]
Ctla4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027164Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is consider [...]
Cd28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027165T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of [...]
Ica1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000027172Islet cell autoantigen 1-like protein.
Wdr12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027173Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Als2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027178Alsin; May act as a GTPase regulator. Controls survival and growth of spinal motoneurons.
Stradb protein networkhttps://string-db.org/network/10090.ENSMUSP00000027185STE20-related kinase adapter protein beta; Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typ [...]
Trak2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027186Trafficking protein, kinesin-binding 2.
Ndufb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027193NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved [...]
Orc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027198Origin recognition complex subunit 2; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define ori [...]
Sgo2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000027202Shugoshin 2; Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres f [...]
Ercc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027214DNA repair protein complementing XP-G cells homolog; Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (N [...]
Ecrg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027217Augurin; Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. ECRG4-induced senescence is char [...]
Khdrbs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027226KH domain-containing, RNA-binding, signal transduction-associated protein 2; RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site select [...]
Slc9a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027231Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
Ptp4a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027232Protein tyrosine phosphatase type IVA 1; Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of diffe [...]
Slc9a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027233Sodium/hydrogen exchanger 4; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by th [...]
Il18rap protein networkhttps://string-db.org/network/10090.ENSMUSP00000027237Interleukin-18 receptor accessory protein; Within the IL18 receptor complex, does not mediate IL18- binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK acti [...]
Il1r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027241Interleukin-1 receptor type 1, membrane form; Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 recep [...]
Il1r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027243Interleukin-1 receptor type 2, membrane form; Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing it [...]
Pdcl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027247Phosducin-like protein 3; Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, increasing its abundance by inhibiting its ubiquitination and degradation. Inhibits the folding activity [...]
Chst10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027249Carbohydrate sulfotransferase 10; Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of H [...]
Rev1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027251DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the fir [...]
Eif5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000027252Eukaryotic translation initiation factor 5B; Plays a role in translation initiation. Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex [...]
Mrpl30 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002725639S ribosomal protein L30, mitochondrial; Belongs to the universal ribosomal protein uL30 family.
Mitd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027257MIT domain-containing protein 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex.
Stk17b protein networkhttps://string-db.org/network/10090.ENSMUSP00000027263Serine/threonine-protein kinase 17B; Acts as a positive regulator of apoptosis. Phosphorylates myosin light chains (By similarity); Belongs to the protein kinase superfamily. CAMK Ser/Thr protein [...]
Asnsd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027264Asparagine synthetase domain-containing protein 1.
Ormdl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027266ORM1-like protein 1; Negative regulator of sphingolipid synthesis; Belongs to the ORM family.
Pms1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027267Postmeiotic segregation increased 1 (S. cerevisiae).
Mstn protein networkhttps://string-db.org/network/10090.ENSMUSP00000027269Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth.
Inpp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027271Inositol polyphosphate 1-phosphatase.
Stat4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027277Signal transducer and activator of transcription 4; Carries out a dual function: signal transduction and activation of transcription.
Nabp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027279SOSS complex subunit B2; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as [...]
Unc50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027285Protein unc-50 homolog; May be involved in cell surface expression of neuronal nicotinic receptors. Binds RNA (By similarity).
Coa5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027286Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process.
Zap70 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027291Tyrosine-protein kinase ZAP-70; Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates motility, adhesion and cytokine expression of mature T-cells, [...]
Plekhb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027297Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes.
Cfc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027298Cryptic protein; Nodal coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation; Belongs to the EGF-CFC (C [...]
Prss39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027299Inactive serine protease 39; May play an important role in the sperm/egg interaction; released during the acrosome reaction; Belongs to the peptidase S1 family.
Ptpn18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027302Tyrosine-protein phosphatase non-receptor type 18; May be involved in growth and differentiation of hematopoietic cells.
Imp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027303U3 small nucleolar ribonucleoprotein protein IMP4; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processi [...]
Prim2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027312DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an e [...]
Zfp142 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027315Zinc finger protein 142; May be involved in transcriptional regulation.
Tm4sf20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027331Transmembrane 4 L6 family member 20; Polytopic transmembrane protein. Inhibits regulated intramembrane proteolysis (RIP) of CREB3L1, inhibiting its activation and the induction of collagen synthe [...]
Fam135a protein networkhttps://string-db.org/network/10090.ENSMUSP00000027337Protein FAM135A.
Sdhaf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027338Succinate dehydrogenase assembly factor 4, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) [...]
Smap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027339Stromal membrane-associated protein 1; GTPase activating protein that acts on ARF6. Plays a role in clathrin-dependent endocytosis. May play a role in erythropoiesis.
Ogfrl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027343Opioid growth factor receptor-like protein 1; Belongs to the opioid growth factor receptor family.
Cyp27a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027356Sterol 26-hydroxylase, mitochondrial; Cytochrome P450 monooxygenase that catalyzes regio- and stereospecific hydroxylation of cholesterol and its derivatives. Hydroxylates (with R stereochemistry [...]
Rnf25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027357E3 ubiquitin-protein ligase RNF25; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NKD2. Stimulates transcription mediated by NF-kappa-B (By sim [...]
Bcs1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000027358Mitochondrial chaperone BCS1; Chaperone necessary for the assembly of mitochondrial respiratory chain complex III. Plays an important role in the maintenance of mitochondrial tubular networks, re [...]
Plcd4 protein networkhttps://string-db.org/network/10090.ENSMUSP000000273621-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4; Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and in [...]
Vil1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027366Villin-1; Epithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. Plays a role in the actin nucleation, actin filament [...]
Ctdsp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027367Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain [...]
Slc11a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027368Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-spe [...]
Pnkd protein networkhttps://string-db.org/network/10090.ENSMUSP00000027370Probable hydrolase PNKD; Probable hydrolase that plays an aggravative role in the development of cardiac hypertrophy via activation of the NF-kappa-B signaling pathway.
Ppm1f protein networkhttps://string-db.org/network/10090.ENSMUSP00000027373Protein phosphatase 1F; Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kina [...]
Tnp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027374Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes [...]
Igfbp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027377Insulin-like growth factor-binding protein 5; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on [...]
Xrcc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027379X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork- [...]
Tmem169 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027380Transmembrane protein 169.
Pecr protein networkhttps://string-db.org/network/10090.ENSMUSP00000027381Peroxisomal trans-2-enoyl-CoA reductase; Participates in chain elongation of fatty acids. Has no 2,4- dienoyl-CoA reductase activity (By similarity); Belongs to the short-chain dehydrogenases/red [...]
Atic protein networkhttps://string-db.org/network/10090.ENSMUSP00000027384Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family.
Bard1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027393BRCA1-associated RING domain protein 1; E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diver [...]
Zfand2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000027394AN1-type zinc finger protein 2B; Plays a role in protein homeostasis by regulating both the translocation and the ubiquitin-mediated proteasomal degradation of nascent proteins at the endoplasmic [...]
Abcb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027396ATP-binding cassette sub-family B member 6, mitochondrial; Binds heme and porphyrins and functions in their ATP- dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.
Stk16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027401Serine/threonine-protein kinase 16; Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphor [...]
Ptprn protein networkhttps://string-db.org/network/10090.ENSMUSP00000027404Receptor-type tyrosine-protein phosphatase-like N; Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancr [...]
Slc23a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027405Solute carrier family 23 member 3.
Des protein networkhttps://string-db.org/network/10090.ENSMUSP00000027409Desmin; Muscle-specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the [...]
Stk11ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000027414Serine/threonine-protein kinase 11-interacting protein; May regulate STK11/LKB1 function by controlling its subcellular localization.
Trip12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027421E3 ubiquitin-protein ligase TRIP12; E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) [...]
Slc16a14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027422Monocarboxylate transporter 14; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. [...]
Itm2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000027425Integral membrane protein 2C; Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-sec [...]
4933407L21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000027426RIKEN cDNA 4933407L21 gene.
Htr2b protein networkhttps://string-db.org/network/10090.ENSMUSP000000274315-hydroxytryptamine receptor 2B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. L [...]
Psmd1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002743226S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a k [...]
Ncl protein networkhttps://string-db.org/network/10090.ENSMUSP00000027438Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensat [...]
Pde6d protein networkhttps://string-db.org/network/10090.ENSMUSP00000027444Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated [...]
Nppc protein networkhttps://string-db.org/network/10090.ENSMUSP00000027449C-type natriuretic peptide; Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be va [...]
Epha4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027451Ephrin type-A receptor 4; Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighbori [...]
Alppl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027455Alkaline phosphatase, germ cell type.
Mrpl44 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002746439S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the r [...]
Serpine2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027467Glia-derived nexin; Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
Chrng protein networkhttps://string-db.org/network/10090.ENSMUSP00000027470Acetylcholine receptor subunit gamma; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting cha [...]
Efhd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027472EF-hand domain-containing protein D1; Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production (By similarity) [...]
Gigyf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027475GRB10-interacting GYF protein 2; Key component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation. In 4EHP-GYF2 the complex, acts as a factor that [...]
Snorc protein networkhttps://string-db.org/network/10090.ENSMUSP00000027476Protein SNORC; Plays a role in the regulation of chondrocyte maturation and postnatal endochondral ossification. May inhibit cell growth stimulation induced by FGF2.
Ndufa10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027478NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed no [...]
Rnpepl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027487Aminopeptidase RNPEPL1; Broad specificity aminopeptidase which preferentially hydrolyzes an N-terminal methionine, citrulline or glutamine.
Capn10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027488Calpain-10; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. May play a role in insuli [...]
Agxt protein networkhttps://string-db.org/network/10090.ENSMUSP00000027491Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes).
Mterf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027492Transcription termination factor 4, mitochondrial; Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S (By similarity). Targets N [...]
Pask protein networkhttps://string-db.org/network/10090.ENSMUSP00000027493PAS domain-containing serine/threonine-protein kinase; Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably [...]
Ppp1r7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027494Protein phosphatase 1 regulatory subunit 7; Regulatory subunit of protein phosphatase 1.
Sept2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027495Septin-2; Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integr [...]
Stk25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027498Serine/threonine-protein kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears [...]
Bok protein networkhttps://string-db.org/network/10090.ENSMUSP00000027499Bcl-2-related ovarian killer protein; Apoptosis regulator that functions through different apoptotic signaling pathways. Plays a roles as pro-apoptotic protein that positively regulates intrinsic [...]
Atg4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000027502Cysteine protease ATG4B; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABAR [...]
Dtymk protein networkhttps://string-db.org/network/10090.ENSMUSP00000027503Thymidylate kinase; Catalyzes the conversion of dTMP to dTDP; Belongs to the thymidylate kinase family.
Ing5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027505Inhibitor of growth protein 5; Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of hi [...]
Pdcd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027507Programmed cell death protein 1; Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals [...]
Dgkd protein networkhttps://string-db.org/network/10090.ENSMUSP00000027517Diacylglycerol kinase.
Spp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027518Secreted phosphoprotein 24; Could coordinate an aspect of bone turnover.
Agap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027521Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1; GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP [...]
Mlph protein networkhttps://string-db.org/network/10090.ENSMUSP00000027528Melanophilin; Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor protein MYO5A.
Rab17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027529Ras-related protein Rab-17; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle bet [...]
Scly protein networkhttps://string-db.org/network/10090.ENSMUSP00000027532Selenocysteine lyase; Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
Klhl30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027533Kelch-like protein 30.
Ilkap protein networkhttps://string-db.org/network/10090.ENSMUSP00000027534Integrin-linked kinase-associated serine/threonine phosphatase 2C; Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose a [...]
Cln8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027554Protein CLN8; Could play a role in cell proliferation during neuronal differentiation and in protection against cell death.
Tnfrsf11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000027559Tumor necrosis factor receptor superfamily member 11A; Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL- mediated osteoclastogenesis. Involved in the regulation of interactions between [...]
Htr4 protein networkhttps://string-db.org/network/10090.ENSMUSP000000275605-hydroxytryptamine receptor 4; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mito [...]
Serpinb13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027564Serpin B13; May play a role in the proliferation or differentiation of keratinocytes.
Serpinb3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000027565Serine (Or cysteine) peptidase inhibitor, clade B, member 3C; Belongs to the serpin family.
Serpinb11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027566Serpin B11; Inhibitor of serine proteases. Has moderate inhibitory activity for trypsin-like peptidases, but also some activity with cysteine peptidases, cathepsin L, K, and V, and the serine pep [...]
Serpinb3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000027567Serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A; Belongs to the serpin family.
Slco6c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027569Solute carrier organic anion transporter family, member 6c1.
Slco6d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027575Solute carrier organic anion transporter family, member 6d1.
Slc35f5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027580Solute carrier family 35 member F5; Putative solute transporter; Belongs to the SLC35F solute transporter family.
Gpr39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027581G-protein coupled receptor 39; Zn(2+) acts as an agonist (By similarity). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second mess [...]
Ccnt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027587Cyclin-T2; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the tra [...]
Ubxn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027592UBX domain-containing protein 4; Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.
Mcm6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027601DNA replication licensing factor MCM6; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiat [...]
Dars protein networkhttps://string-db.org/network/10090.ENSMUSP00000027602Aspartate--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and [...]
Rgs18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027603Regulator of G-protein signaling 18; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G [...]
F13b protein networkhttps://string-db.org/network/10090.ENSMUSP00000027615Coagulation factor XIII B chain; The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin [...]
Tsn protein networkhttps://string-db.org/network/10090.ENSMUSP00000027623Translin; DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene [...]
Nifk protein networkhttps://string-db.org/network/10090.ENSMUSP00000027626MKI67 FHA domain-interacting nucleolar phosphoprotein.
Tfcp2l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027629Transcription factor CP2-like protein 1; Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs). With Klf2, acts as the major effector [...]
Marco protein networkhttps://string-db.org/network/10090.ENSMUSP00000027639Macrophage receptor MARCO; Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria. Also plays a role in binding of unopsonized particles by alveolar macrophages ( [...]
Atp6v1g3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027643V-type proton ATPase subunit G 3; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in e [...]
Nr5a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027649Nuclear receptor subfamily 5 group A member 2; Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis [...]
Cd55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027650Complement decay-accelerating factor, GPI-anchored; This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally gen [...]
Ddx59 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027655Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily.
C4bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000027657C4b-binding protein; Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also ac [...]
Pkp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027667Plakophilin-1; Seems to play a role in junctional plaques; Belongs to the beta-catenin family.
Il20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027673Interleukin-20; Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3; Belongs to the IL-10 family.
Pigr protein networkhttps://string-db.org/network/10090.ENSMUSP00000027675Polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the [...]
Gpr37l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027682G-protein coupled receptor 37-like 1; G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK [...]
Arl8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000027684ADP-ribosylation factor-like protein 8A; Plays a role in lysosomes motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for [...]
Ube2t protein networkhttps://string-db.org/network/10090.ENSMUSP00000027687Ubiquitin-conjugating enzyme E2 T; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induc [...]
Rassf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027688Ras association domain-containing protein 5; Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to i [...]
Avpr1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000027690Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system; Belon [...]
Rab29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027693Ras-related protein Rab-7L1; The small GTPases Rab are key regulators in vesicle trafficking (By similarity). Essential for maintaining the integrity of endosome-trans-Golgi network structure (By [...]
Slc45a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027695Solute carrier family 45 member 3; Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family.
Cdk18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027697Cyclin-dependent kinase 18; May play a role in signal transduction cascades in terminally differentiated cells; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2 [...]
Lrrn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027706Leucine-rich repeat protein 2, neuronal.
Klhl12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027725Kelch-like protein 12; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(K [...]
Cyb5r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027726NADH-cytochrome b5 reductase 1; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemogl [...]
Myog protein networkhttps://string-db.org/network/10090.ENSMUSP00000027730Myogenin; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential [...]
Zc3h11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000027736Zinc finger CCCH domain-containing protein 11A; Involved in nuclear mRNA export; probably mediated by association with the TREX complex.
Lhx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027740LIM/homeobox protein Lhx4; May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung. Binds preferentially to methylated DN [...]
Xpr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027741Xenotropic and polytropic retrovirus receptor 1; Plays a role in phosphate homeostasis. Mediates phosphate export from the cell. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyp [...]
Stx6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027743Syntaxin-6; Involved in intracellular vesicle trafficking; Belongs to the syntaxin family.
Mr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027744Major histocompatibility complex class I-related gene protein; Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites (By similarity). Involved in the development a [...]
Rgs16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027748Regulator of G-protein signaling 16; Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby d [...]
Lamc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027752Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development [...]
Lamc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027753Laminin subunit gamma-2; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development [...]
Rgl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027760Ral guanine nucleotide dissociation stimulator-like 1; Probable guanine nucleotide exchange factor.
Coq8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000027766Atypical kinase COQ8A, mitochondrial; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respi [...]
Ahctf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027768Protein ELYS; Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chro [...]
Tfb2m protein networkhttps://string-db.org/network/10090.ENSMUSP00000027769Dimethyladenosine transferase 2, mitochondrial; S-adenosyl-L-methionine-dependent rRNA methyltransferase which may methylate two specific adjacent adenosines in the loop of a conserved hairpin ne [...]
Efcab2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027775Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the dis [...]
Parp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027777Poly [ADP-ribose] polymerase 1; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. Mainly mediates glutamate and aspartate ADP-ribosy [...]
Mixl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027778Homeobox protein MIXL1; Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the pr [...]
Acbd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027780Golgi resident protein GCP60; Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi (By similarity). [...]
Cox20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027781Cytochrome c oxidase assembly protein COX20, mitochondrial; Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Acts as a chape [...]
Desi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027783Deubiquitinase DESI2; Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabiliz [...]
Sdccag8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027785Serologically defined colon cancer antigen 8 homolog; Plays a role in the establishment of cell polarity and epithelial lumen formation. Plays also an essential role in ciliogenesis and subsequen [...]
Srp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027792Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with [...]
Nvl protein networkhttps://string-db.org/network/10090.ENSMUSP00000027797Nuclear valosin-containing protein-like; Participates in the assembly of the telomerase holoenzyme and effecting of telomerase activity via its interaction with TERT. Involved in both early and l [...]
Tmem63a protein networkhttps://string-db.org/network/10090.ENSMUSP00000027800CSC1-like protein 1; Acts as an osmosensitive calcium-permeable cation channel. Mechanosensitive ion channel that converts mechanical stimuli into a flow of ion. Belongs to the CSC1 (TC 1.A.17) f [...]
Pycr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027802Pyrroline-5-carboxylate reductase 2; Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation [...]
Opn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027809Opsin-3; May play a role in encephalic photoreception; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Fh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027810Fumarate hydratase, mitochondrial; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. Experiments in different species have demonstrated that specific isoforms of th [...]
Mptx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027816Mucosal pentraxin; Belongs to the pentraxin family.
Spta1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027817Spectrin alpha chain, erythrocytic 1; Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the c [...]
Apcs protein networkhttps://string-db.org/network/10090.ENSMUSP00000027824Serum amyloid P-component; Belongs to the pentraxin family.
Dusp23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027826Dual specificity protein phosphatase 23; Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAP [...]
Slamf9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027830SLAM family member 9; May play a role in the immune response.
Fmo9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027843Dimethylaniline monooxygenase [N-oxide-forming].
Tada1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027846Transcriptional adapter 1; Probably involved in transcriptional regulation.
Adcy10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027852Adenylate cyclase type 10; Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels (By similarit [...]
Mpc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027853Mitochondrial pyruvate carrier 2; Mediates the uptake of pyruvate into mitochondria.
Dcaf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027856DDB1- and CUL4-associated factor 6; Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor [...]
Tbx19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027859T-box transcription factor TBX19; Transcriptional regulator involved in developmental processes. Can activate POMC gene expression and repress the alpha glycoprotein subunit and thyroid-stimulati [...]
Xcl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027860Lymphotactin; Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell d [...]
Dpt protein networkhttps://string-db.org/network/10090.ENSMUSP00000027861Dermatopontin; Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. E [...]
Atp1b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027863Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) io [...]
Blzf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027866Golgin-45; Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface.
Ccdc181 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027867Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
Sell protein networkhttps://string-db.org/network/10090.ENSMUSP00000027871L-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial v [...]
Sele protein networkhttps://string-db.org/network/10090.ENSMUSP00000027874E-selectin; Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May h [...]
Scyl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027876Protein-associating with the carboxyl-terminal domain of ezrin; May play a role in regulating cell adhesion/migration complexes in migrating cells.
Kifap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027877Kinesin-associated protein 3; Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeri [...]
Prrx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027878Paired mesoderm homeobox protein 1; Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein bind [...]
Angptl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027885Angiopoietin-related protein 1.
Abl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027888Tyrosine-protein kinase ABL2; Non-receptor tyrosine-protein kinase that plays an ABL1- overlapping role in key processes linked to cell growth and survival such as cytoskeleton remodeling in resp [...]
Nphs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027896Podocin; Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.
Smyd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027897N-lysine methyltransferase SMYD2; Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys [...]
Esrrg protein networkhttps://string-db.org/network/10090.ENSMUSP00000027906Estrogen-related receptor gamma; Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter gen [...]
Iars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027921Isoleucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
Mark1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027929Serine/threonine-protein kinase MARK1; Serine/threonine-protein kinase (By similarity). Involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2 and MAP4. Phosphory [...]
Nek2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027931Serine/threonine-protein kinase Nek2; Protein kinase which is involved in the control of centrosome separation and bipolar spindle formation in mitotic cells and chromatin condensation in meiotic [...]
Dtl protein networkhttps://string-db.org/network/10090.ENSMUSP00000027933Denticleless protein homolog; Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA sy [...]
Pacc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027940Proton-activated chloride channel; Proton-activated chloride channel that mediates import of chloride ion in response to extracellular acidic pH. Involved in acidosis-induced cell death by mediat [...]
Atf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027941Cyclic AMP-dependent transcription factor ATF-3; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Re [...]
Batf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027943Basic leucine zipper transcriptional factor ATF-like 3; AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts [...]
Plxna2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027952Plexin-A2; Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growt [...]
Suv39h2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027956Histone-lysine N-methyltransferase SUV39H2; Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation [...]
Cfap126 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027959Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. R [...]
Hspa14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027961Heat shock 70 kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding- competent state. In the RAC compl [...]
Fam107b protein networkhttps://string-db.org/network/10090.ENSMUSP00000027965Protein FAM107B.
Fcgr2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000027966Low affinity immunoglobulin gamma Fc region receptor II; Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory fun [...]
Dusp12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027970Dual specificity protein phosphatase 12; Dual specificity phosphatase; can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues. Can dephosphorylate glucokinase (in [...]
Sephs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027973Selenide, water dikinase 1; Synthesizes selenophosphate from selenide and ATP; Belongs to the selenophosphate synthase 1 family. Class II subfamily.
Atf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027974Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded pro [...]
Phyh protein networkhttps://string-db.org/network/10090.ENSMUSP00000027975Phytanoyl-CoA dioxygenase, peroxisomal; Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.
Uhmk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027979Serine/threonine-protein kinase Kist; Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved i [...]
Ccdc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027988Coiled-coil domain-containing protein 3; Negatively regulates TNF-alpha-induced pro-inflammatory response in endothelial cells (ECs) via inhibition of TNF-alpha-induced NF-kappaB activation in EC [...]
Hsd17b7 protein networkhttps://string-db.org/network/10090.ENSMUSP000000279893-keto-steroid reductase; Responsible for the reduction of the keto group on the C-3 of sterols; Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.
Rgs4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027991Regulator of G-protein signaling 4; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on [...]
Enkur protein networkhttps://string-db.org/network/10090.ENSMUSP00000027992Enkurin; Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel.
Rgs5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000027997Regulator of G-protein signaling 5; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G( [...]
Lmx1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000028003LIM homeobox transcription factor 1-alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the [...]
Aldh9a1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000280044-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a bro [...]
Mgst3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028005Microsomal glutathione S-transferase 3; Catalyzes oxydation of hydroxy-fatty acids. May participate to the lipid metabolism; Belongs to the MAPEG family.
Fmo3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028010Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well a [...]
Eef1aknmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000028017eEF1A lysine and N-terminal methyltransferase; Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore invo [...]
Myoc protein networkhttps://string-db.org/network/10090.ENSMUSP00000028020Myocilin, C-terminal fragment; Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matri [...]
Tnfsf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028024Tumor necrosis factor ligand superfamily member 4; Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production; Belongs to the tumor necrosis factor family.
Mrc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028045Macrophage mannose receptor 1; Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fung [...]
Rabgap1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000028049Rab GTPase-activating protein 1-like; GTP-hydrolysis activating protein (GAP) for small GTPase RAB22A, converting active RAB22A-GTP to the inactive form RAB22A-GDP (By similarity). Plays a role i [...]
Rsu1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028059Ras suppressor protein 1; Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro.
Vim protein networkhttps://string-db.org/network/10090.ENSMUSP00000028062Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitoc [...]
Ptf1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000028068Pancreas transcription factor 1 subunit alpha; Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role i [...]
Bmi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028071Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, incl [...]
Mllt10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028076Protein AF-10; Probably involved in transcriptional regulation. Binds to cruciform DNA (By similarity). In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 ' [...]
Nebl protein networkhttps://string-db.org/network/10090.ENSMUSP00000028080LIM zinc-binding domain-containing Nebulette; Binds to actin and plays an important role in the assembly of the Z-disk. Isoform 2 might play a role in the assembly of focal adhesion (By similarit [...]
Plxdc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028081Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family.
Psmb7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028083Proteasome subunit beta type-7; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles wi [...]
Ppp6c protein networkhttps://string-db.org/network/10090.ENSMUSP00000028087Serine/threonine-protein phosphatase 6 catalytic subunit; Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response [...]
Orc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028098Origin recognition complex subunit 4; Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 (By similarity). Component of the origin recognition complex (ORC) that binds ori [...]
Epc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028100Enhancer of polycomb homolog 1; Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleos [...]
Kif5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000028102Kinesin heavy chain isoform 5C; Involved in synaptic transmission (By similarity). Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Mediate [...]
Lypd6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000028103Ly6/PLAUR domain-containing protein 6B; Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent ma [...]
Mindy3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028105Ubiquitin carboxyl-terminal hydrolase MINDY-3; Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.
Itga8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028106Integrin alpha-8 heavy chain; Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures [...]
Il2ra protein networkhttps://string-db.org/network/10090.ENSMUSP00000028111Interleukin-2 receptor subunit alpha; Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress [...]
Potegl protein networkhttps://string-db.org/network/10090.ENSMUSP00000028113POTE ankyrin domain family, member G-like.
Yme1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028117ATP-dependent zinc metalloprotease YME1L1; ATP-dependent metalloprotease that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial interm [...]
Prkcq protein networkhttps://string-db.org/network/10090.ENSMUSP00000028118Protein kinase C theta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that mediates non-redundant functions in T-cell receptor (TCR) [...]
Mastl protein networkhttps://string-db.org/network/10090.ENSMUSP00000028119Serine/threonine-protein kinase greatwall; Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation o [...]
Gad2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028123Glutamate decarboxylase 2; Catalyzes the production of GABA.
Slc2a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028129Solute carrier family 2, facilitated glucose transporter member 8; Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Also able to mediate the [...]
Coq4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028137Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzy [...]
Med27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028139Mediator of RNA polymerase II transcription subunit 27; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Fpgs protein networkhttps://string-db.org/network/10090.ENSMUSP00000028148Folylpolyglutamate synthase, mitochondrial; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of [...]
Dpm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028151Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; [...]
Slc25a25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028160Calcium-binding mitochondrial carrier protein SCaMC-2; Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mi [...]
Cel protein networkhttps://string-db.org/network/10090.ENSMUSP00000028161Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters [...]
Ptges2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028162Prostaglandin E synthase 2 truncated form; Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (By similarity). May also have transactivation activity tow [...]
Nr4a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028166Nuclear receptor subfamily 4 group A member 2; Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during develop [...]
Cytip protein networkhttps://string-db.org/network/10090.ENSMUSP00000028175Cytohesin-interacting protein; By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.
Olfm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028177Noelin; Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth c [...]
Acvr1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000028178Activin receptor type-1C; Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonin [...]
Fcnb protein networkhttps://string-db.org/network/10090.ENSMUSP00000028179Ficolin-2; May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin (By similarity); Belongs to the ficolin lectin family.
Lamc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028187Laminin subunit gamma-3; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development [...]
Fibcd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028188Fibrinogen C domain-containing protein 1; Acetyl group-binding receptor which shows a high-affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carboh [...]
Tor1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000028199Torsin-1B; May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. Plays a role in non- neural cells nuclear envelope and endoplasmic reticulum in [...]
Tor1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000028200Torsin-1A; Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Invo [...]
BC005624 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028205Telomere length and silencing protein 1 homolog; Involved in the regulation of telomeric heterochromatin assembly and control of telomere length.
Dolpp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028209Dolichyldiphosphatase 1; Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rat [...]
Fbxw2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028220F-box/WD repeat-containing protein 2; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Hspa5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028222Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen. Involved in the correct foldi [...]
Kynu protein networkhttps://string-db.org/network/10090.ENSMUSP00000028223Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preferen [...]
Psmd5 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002822526S proteasome non-ATPase regulatory subunit 5; Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the [...]
Phf19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028232PHD finger protein 19; Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Probably involved in the transition from an acti [...]
Hc protein networkhttps://string-db.org/network/10090.ENSMUSP00000028233Complement C5 alpha' chain; Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient [...]
Rab14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028238Ras-related protein Rab-14; Regulates, together with its guanine nucleotide exchange factor, DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 shedding and cell-cell adhesion [...]
Gsn protein networkhttps://string-db.org/network/10090.ENSMUSP00000028239Gelsolin; Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote [...]
Stom protein networkhttps://string-db.org/network/10090.ENSMUSP00000028241Erythrocyte band 7 integral membrane protein; Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity. Belongs to the band 7/mec-2 family.
4930568D16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000028243N-acetyllactosaminide alpha-1,3-galactosyltransferase-like 1; Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on [...]
Ttll11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028248Tubulin polyglutamylase TTLL11; Polyglutamase which preferentially modifies alpha-tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiati [...]
Mrrf protein networkhttps://string-db.org/network/10090.ENSMUSP00000028250Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by rec [...]
Rbm18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028251Probable RNA-binding protein 18.
Grb14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028252Growth factor receptor-bound protein 14; Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the act [...]
Morn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028256MORN repeat-containing protein 5.
Gca protein networkhttps://string-db.org/network/10090.ENSMUSP00000028257Grancalcin; Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.
Ifih1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028259Interferon-induced helicase C domain-containing protein 1; Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and i [...]
Psmd14 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002827826S proteasome non-ATPase regulatory subunit 14; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a [...]
Strbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000028279Spermatid perinuclear RNA-binding protein; Involved in spermatogenesis and sperm function. Plays a role in regulation of cell growth (By similarity). Binds to double-stranded DNA and RNA (By simi [...]
Col5a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028280Collagen alpha-1(V) chain; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collag [...]
Lcn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028283Vomeronasal secretory protein 2; Transport of lipophilic molecules, possible pheromone- carrier.
Agpat2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000282861-acyl-sn-glycerol-3-phosphate acyltransferase beta; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by in [...]
Notch1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028288Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand a [...]
Dnlz protein networkhttps://string-db.org/network/10090.ENSMUSP00000028295DNL-type zinc finger protein; May function as a co-chaperone towards HSPA9/mortalin which, by itself, is prone to self-aggregation.
1700019N19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000028299Uncharacterized protein C10orf82 homolog.
Lhx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028302LIM/homeobox protein Lhx3; Required for the establishment of the specialized cells of the pituitary gland and the nervous system (By similarity). Involved in the development of interneurons and m [...]
Lcn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028304Vomeronasal secretory protein 1; Transport of lipophilic molecules, possible pheromone- carrier.
Lcn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028306Epididymal-specific lipocalin-5, major form; Associates with spermatozoa in the epididymal fluid but does not bind tightly to them. Binds both all-trans and 13-cis retinoic acid. May act as a ret [...]
Fcna protein networkhttps://string-db.org/network/10090.ENSMUSP00000028307Ficolin-1; Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen- associated molecular patterns (PAMPs) displayed on microbes [...]
Ccdc183 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028309Coiled-coil domain-containing protein 183.
Lcn12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028312Epididymal-specific lipocalin-12; Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility (By similarity); Belongs to the [...]
Nmi protein networkhttps://string-db.org/network/10090.ENSMUSP00000028314N-myc-interactor; May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription (By similarity [...]
Entpd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028328Ectonucleoside triphosphate diphosphohydrolase 2; In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal exte [...]
Sapcd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028329Suppressor APC domain-containing protein 2; Plays a role in planar mitotic spindle orientation in retinal progenitor cells (RPCs) and promotes the production of symmetric terminal divisions. Nega [...]
Dpp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028332Dipeptidyl peptidase 2; Plays an important role in the degradation of some oligopeptides; Belongs to the peptidase S28 family.
Grin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028335Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensi [...]
Arl6ip6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028336ADP-ribosylation factor-like protein 6-interacting protein 6.
Lrrc26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028337Leucine-rich repeat-containing protein 26; Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels [...]
Tmem210 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028340Transmembrane protein 210.
Anapc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028341Anaphase-promoting complex subunit 2; Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 [...]
Ssna1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028342Sjoegren syndrome nuclear autoantigen 1 homolog.
Fam166a protein networkhttps://string-db.org/network/10090.ENSMUSP00000028346Protein FAM166A; Belongs to the UPF0605 family.
Arrdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028349Arrestin domain-containing protein 1; Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates. Through an ubiquitination-dependent mechanism plays for instance a [...]
Zmynd19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028350Zinc finger MYND domain-containing protein 19; May be involved as a regulatory molecule in GPR24/MCH-R1 signaling.
Dph7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028351Diphthine methyltransferase; Catalyzes the demethylation of diphthine methyl ester to form diphthine, an intermediate diphthamide biosynthesis, a post- translational modification of histidine whi [...]
Pax8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028355Paired box protein Pax-8; Thought to encode a transcription factor. It may have a role in kidney cell differentiation. May play a regulatory role in mammalian development.
Il1f5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028360Interleukin-36 receptor antagonist protein; Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2/IL-36R and preventing its association with the coreceptor [...]
Il1f6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028361Interleukin-36 alpha; Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflamma [...]
Ly75 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028362Lymphocyte antigen 75; Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B ly [...]
Il1f8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028363Interleukin-36 beta; Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammat [...]
Wdsub1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028368WD repeat, SAM and U-box domain-containing protein 1.
Dapl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028369Death-associated protein-like 1; May play a role in the early stages of epithelial differentiation or in apoptosis.
Scn2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000028377Sodium channel protein type 2 subunit alpha; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage diff [...]
Galnt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028378Polypeptide N-acetylgalactosaminyltransferase 3; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threon [...]
Nup35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028382Nucleoporin NUP35; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components [...]
Dusp19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028384Dual specificity protein phosphatase 19; Has a dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificit [...]
Frzb protein networkhttps://string-db.org/network/10090.ENSMUSP00000028389Secreted frizzled-related protein 3; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell gr [...]
Dnajc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028392DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient foldin [...]
Ube2e3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028398Ubiquitin-conjugating enzyme E2 E3; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'- [...]
Cybrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028403Cytochrome b reductase 1; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating [...]
Hat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028408Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at [...]
Xirp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028410Xin actin-binding repeat-containing protein 2; Protects actin filaments from depolymerization.
Cyct protein networkhttps://string-db.org/network/10090.ENSMUSP00000028430Cytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome red [...]
P2rx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028465P2X purinoceptor 3; Receptor for ATP that acts as a ligand-gated cation channel (By similarity). Plays a role in sensory perception. Required for normal perception of pain. Required for normal ta [...]
Prg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028466Proteoglycan 3; Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP.
Prg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028467Eosinophil granule major basic protein; Cytotoxin and helminthotoxin. MBP also induces non-cytolytic histamine release from basophils. It is involved in antiparasitic defense mechanisms and immun [...]
Slc43a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028469Large neutral amino acids transporter small subunit 3; Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 a [...]
Timm10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028470Mitochondrial import inner membrane translocase subunit Tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mi [...]
Smtnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028471Smoothelin-like protein 1; Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylati [...]
Itgav protein networkhttps://string-db.org/network/10090.ENSMUSP00000028499Integrin alpha-V heavy chain; The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase- 2, osteopontin, osteomodulin, pr [...]
Gorasp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028509Golgi reassembly-stacking protein 2; Plays a role in assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meio [...]
Mtx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028511Metaxin-2; Involved in transport of proteins into the mitochondrion.
Chrna1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028515Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting cha [...]
Ola1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028517Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
Kif18a protein networkhttps://string-db.org/network/10090.ENSMUSP00000028527Kinesin-like protein KIF18A; Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement du [...]
Fshb protein networkhttps://string-db.org/network/10090.ENSMUSP00000028533Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FS [...]
Arl14ep protein networkhttps://string-db.org/network/10090.ENSMUSP00000028536ARL14 effector protein; Through its interaction with ARL14 and MYO1E, may connect MHC class II-containing cytoplasmic vesicles to the actin network and hence controls the movement of these vesicl [...]
Slc12a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028549Solute carrier family 12 member 6; Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells; Belongs to [...]
Emc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028551ER membrane protein complex subunit 4; May mediate anti-apoptotic activity.
Katnbl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028552KATNB1-like protein 1; Regulates microtubule-severing activity of KATNAL1 in a concentration-dependent manner in vitro.
Nop10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028553H/ACA ribonucleoprotein complex subunit 3; Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes p [...]
Lpcat4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028554Lysophospholipid acyltransferase LPCAT4; Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates; converts lysophosphatidylethanolam [...]
A26c3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028577ANKRD26-like family C, member 3.
Ccdc34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028580Coiled-coil domain-containing protein 34.
Lin7c protein networkhttps://string-db.org/network/10090.ENSMUSP00000028583Protein lin-7 homolog C; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated mu [...]
Commd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028584COMM domain-containing protein 9; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B. Modulates Na(+) transport in epithelial cel [...]
Eif3m protein networkhttps://string-db.org/network/10090.ENSMUSP00000028592Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein [...]
Prrg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028593Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS (By similarity). Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ( [...]
Depdc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028595DEP domain-containing protein 7.
Cstf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028599Cleavage stimulation factor subunit 3; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs.
Hipk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028600Homeodomain-interacting protein kinase 3; Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to [...]
Fbxo3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028603F-box only protein 3; Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leadi [...]
Caprin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028607Caprin-1; May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly an [...]
Nat10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028608RNA cytidine acetyltransferase; RNA cytidine acetyltransferase that catalyzes the formation of N(4)-acetylcytidine (ac4C) modification on mRNAs, 18S rRNA and tRNAs. Catalyzes ac4C modification of [...]
Cat protein networkhttps://string-db.org/network/10090.ENSMUSP00000028610Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.
Pamr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028612Inactive serine protease PAMR1; May play a role in regeneration of skeletal muscle; Belongs to the peptidase S1 family.
Api5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028617Apoptosis inhibitor 5; Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated D [...]
Hsd17b12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028619Very-long-chain 3-oxoacyl-CoA reductase; Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the [...]
Ext2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028623Exostosin-2; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appe [...]
Gatm protein networkhttps://string-db.org/network/10090.ENSMUSP00000028624Glycine amidinotransferase, mitochondrial; Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. [...]
Slc12a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028630Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential ro [...]
Meis2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028639Homeobox protein Meis2; Involved in transcriptional regulation. Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabiliz [...]
Cd82 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028644CD82 antigen; Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway; Belongs to the tetraspanin (TM4SF) family.
Syt13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028648Synaptotagmin-13; May be involved in transport vesicle docking to the plasma membrane.
Pex16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028650Peroxisomal membrane protein PEX16; Required for peroxisome membrane biogenesis. May play a role in early stages of peroxisome assembly. Can recruit other peroxisomal proteins, such as PEX3 and P [...]
Duoxa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028656Dual oxidase maturation factor 2; Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2. May play a role in thyroid hormone synth [...]
Terb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028661Telomere repeats-binding bouquet formation protein 2; Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homolo [...]
Creb3l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028663Processed cyclic AMP-responsive element-binding protein 3-like protein 1; Transcription factor involved in unfolded protein response (UPR). Binds the DNA consensus sequence 5'-GTGXGCXGC-3' (By si [...]
Patl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028665Protein PAT1 homolog 2; RNA-binding protein that acts as a translational repressor.
Eif3j1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028668Eukaryotic translation initiation factor 3 subunit J-A; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of prote [...]
Mdk protein networkhttps://string-db.org/network/10090.ENSMUSP00000028672Midkine; Secreted protein that functions as cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non- proteoglycan receptors. Binds cell-surface proteoglycan r [...]
Ell3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028679RNA polymerase II elongation factor ELL3; Enhancer-binding elongation factor that specifically binds enhancers in embryonic stem cells (ES cells), marks them, and is required for their future act [...]
F2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028681Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protei [...]
Pdia3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028683Protein disulfide-isomerase A3.
Lrp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028689Low-density lipoprotein receptor-related protein 4; Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a [...]
Arfgap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028691ADP-ribosylation factor GTPase-activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). May regulate coatomer-mediated protein transport from the Golgi complex [...]
Ddb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028696DNA damage-binding protein 2; Required for DNA repair. Binds to DDB1 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damag [...]
Hao1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028704Hydroxyacid oxidase 1; Has 2-hydroxyacid oxidase activity. Most active on the 2- carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palm [...]
Tgm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028721Protein-glutamine gamma-glutamyltransferase 5; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope o [...]
Snap25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028727Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Ass [...]
Ubr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028728E3 ubiquitin-protein ligase UBR1; E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are desta [...]
Jag1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028735Protein jagged-1; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early [...]
Ttbk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028740Tau-tubulin kinase 2; Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting th [...]
Capn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028749Calpain-3; Calcium-regulated non-lysosomal thiol-protease; Belongs to the peptidase C2 family.
Ehd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028755EH domain-containing protein 4; ATP- and membrane-binding protein that probably controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in early endosomal transport.
Itpka protein networkhttps://string-db.org/network/10090.ENSMUSP00000028758Inositol-trisphosphate 3-kinase A; Belongs to the inositol phosphokinase (IPK) family.
Ltk protein networkhttps://string-db.org/network/10090.ENSMUSP00000028759Leukocyte tyrosine kinase receptor; Receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular [...]
Ubox5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028761RING finger protein 37; May have a ubiquitin-protein ligase activity acting as an E3 ubiquitin-protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substr [...]
Tyro3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028763Tyrosine-protein kinase receptor TYRO3; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Re [...]
Oxt protein networkhttps://string-db.org/network/10090.ENSMUSP00000028764Oxytocin-neurophysin 1; Neurophysin 1 specifically binds oxytocin.
Rtf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028767RNA polymerase-associated protein RTF1 homolog; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of dev [...]
Ndufaf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028768Complex I intermediate-associated protein 30, mitochondrial; Chaperone protein involved in early stages of the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
Chac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028780Glutathione-specific gamma-glutamylcyclotransferase 1; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma [...]
Atrn protein networkhttps://string-db.org/network/10090.ENSMUSP00000028781Attractin; Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines (By similarity). May play a role in melanocortin signali [...]
Gfra4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028787GDNF family receptor alpha-4; Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnata [...]
Siglec1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028794Sialoadhesin; Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including [...]
Rad51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028795DNA repair protein RAD51 homolog 1; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single and double-stranded DNA [...]
Rpusd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028796RNA pseudouridylate synthase domain-containing protein 2; Belongs to the pseudouridine synthase RluA family.
1700037H04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000028800UPF0687 protein C20orf27 homolog; Belongs to the UPF0687 family.
Knl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028802Kinetochore scaffold 1; Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Directly links spindle check [...]
Cdc25b protein networkhttps://string-db.org/network/10090.ENSMUSP00000028804M-phase inducer phosphatase 2; Tyrosine protein phosphatase which functions as a dosage- dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and absci [...]
Ivd protein networkhttps://string-db.org/network/10090.ENSMUSP00000028807Isovaleryl-CoA dehydrogenase, mitochondrial; Belongs to the acyl-CoA dehydrogenase family.
Rassf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028814Ras association domain-containing protein 2; Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting [...]
Slc23a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028815Solute carrier family 23 member 2; Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate (By similarity).
Pcna protein networkhttps://string-db.org/network/10090.ENSMUSP00000028817Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elo [...]
Fsip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028821Fibrous sheath-interacting protein 1; Belongs to the FSIP1 family.
Fam98b protein networkhttps://string-db.org/network/10090.ENSMUSP00000028825Protein FAM98B; Positively stimulates PRMT1-induced protein arginine dimethylated arginine methylation.
Chgb protein networkhttps://string-db.org/network/10090.ENSMUSP00000028826Secretogranin-1; Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.
Spred1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028829Sprouty-related, EVH1 domain-containing protein 1; Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase. Negatively regulates hematopoiesis of bone marrow.
Mcm8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028831DNA helicase MCM8; Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross- links (ICLs) by homologous recombination (H [...]
Tmco5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028834Transmembrane and coiled-coil domain-containing protein 5A; Belongs to the TMCO5 family.
Crls1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028835Cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylg [...]
Bmp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028836Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 s [...]
Hdc protein networkhttps://string-db.org/network/10090.ENSMUSP00000028838Histidine decarboxylase; Catalyzes the biosynthesis of histamine from histidine.
Usp50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028842Putative ubiquitin carboxyl-terminal hydrolase 50; May recognize and hydrolyze the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as wel [...]
Sppl2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000028844Signal peptide peptidase-like 2A; Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in FASLG, ITM [...]
Dusp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028846Dual specificity protein phosphatase 2; Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
Fahd2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000028848Fumarylacetoacetate hydrolase domain-containing protein 2A; May have hydrolase activity.
Kcnip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028850Calsenilin; Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding [...]
Mrps5 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002885228S ribosomal protein S5, mitochondrial; Belongs to the universal ribosomal protein uS5 family.
Mal protein networkhttps://string-db.org/network/10090.ENSMUSP00000028854Myelin and lymphocyte protein; Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Plays a role in the maintenance of the my [...]
Prom2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028855Prominin-2.
Mall protein networkhttps://string-db.org/network/10090.ENSMUSP00000028856MAL-like protein.
Nphp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028857Nephrocystin-1; Together with BCAR1 it may play a role in the control of epithelial cell polarity. Involved in the organization of apical junctions in kidney cells, together with NPHP4 and RPGRIP [...]
Bub1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028858Mitotic checkpoint serine/threonine-protein kinase BUB1; Serine/threonine-protein kinase that performs 2 crucial functions during mitosis: it is essential for spindle-assembly checkpoint signalin [...]
Acoxl protein networkhttps://string-db.org/network/10090.ENSMUSP00000028859Acyl-coenzyme A oxidase-like protein; Belongs to the acyl-CoA oxidase family.
Zc3h8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028866Zinc finger CCCH domain-containing protein 8; Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II an [...]
Slc20a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028880Sodium-dependent phosphate transporter 1; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for no [...]
Il1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000028881Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and [...]
Il1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000028882Interleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activit [...]
Pdyn protein networkhttps://string-db.org/network/10090.ENSMUSP00000028883Alpha-neoendorphin; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (B [...]
Tgm6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028888Transglutaminase 6.
Idh3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000028892Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
Cpxm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028897Probable carboxypeptidase X1; May be involved in cell-cell interactions. No carboxypeptidase activity was found yet.
Vps16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028900Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pa [...]
Otor protein networkhttps://string-db.org/network/10090.ENSMUSP00000028902Otoraplin; Belongs to the MIA/OTOR family.
Pcsk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028905Neuroendocrine convertase 2; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon f [...]
Mgme1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028910Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity [...]
Kat14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028911Cysteine-rich protein 2-binding protein; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to [...]
Polr3f protein networkhttps://string-db.org/network/10090.ENSMUSP00000028914DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripher [...]
Rbbp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028915Putative hydrolase RBBP9; Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. [...]
Sec23b protein networkhttps://string-db.org/network/10090.ENSMUSP00000028916Protein transport protein Sec23B; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main fu [...]
Dtd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028917D-aminoacyl-tRNA deacylase 1; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarg [...]
Scp2d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028918SCP2 sterol-binding domain-containing protein 1.
Xrn2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000289215'-3' exoribonuclease 2; Possesses 5'->3' exoribonuclease activity. May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenyl [...]
Napb protein networkhttps://string-db.org/network/10090.ENSMUSP00000028926Beta-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus; Belongs to the SNAP family.
Gzf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028928GDNF-inducible zinc finger protein 1; Transcriptional repressor that binds the GZF1 responsive element (GRE) (consensus: 5'-TGCGCN[TG][CA]TATA-3'). May be regulating VSX2/HOX10 expression.
Cstdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028933Cystatin-14; May play a specialized role in spermatogenesis.
Cst11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028934Cystatin-11; Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization. Belongs to the cystatin family.
Cst9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028935Cystatin-9; May be involved in testis development. May play a role in hematopoietic differentiation or inflammation (By similarity). Has immunomodulatory and antimicrobial functions against Franc [...]
Cstdc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028937Cystatin domain-containing 2.
Cst3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028938Cystatin-C; As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity; Belongs to the cystatin family.
Acss1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028944Acetyl-coenzyme A synthetase 2-like, mitochondrial; Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much [...]
Gins1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028948DNA replication complex GINS protein PSF1; Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DN [...]
Sdcbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028950Syntenin-2; Binds phosphatidylinositol 4,5-bisphosphate (PIP2). May play a role in the organization of nuclear PIP2, cell division and cell survival.
Angpt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028955Angiopoietin-4; Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis.
Tbc1d20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028963TBC1 domain family member 20; GTPase-activating protein specific for Rab1 and Rab2 small GTPase families for which it can accelerate the intrinsic GTP hydrolysis rate by more than five orders of [...]
Defb22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028966Beta-defensin 22; Probable component of sperm glycocalyx. Likely protects and facilitates transport of sperm in the female reproductive tract. Probably released from the sperm surface during capa [...]
Mylk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028970Myosin light chain kinase 2, skeletal/cardiac muscle; Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N-terminus of a myosin lig [...]
Pdrg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028972P53 and DNA damage-regulated protein 1; May play a role in chaperone-mediated protein folding. Belongs to the prefoldin subunit beta family.
Kif3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000028977Kinesin-like protein KIF3B, N-terminally processed; Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous [...]
Mapre1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028981Microtubule-associated protein RP/EB family member 1; Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promo [...]
Sun5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028982SUN domain-containing protein 5; Plays an essential role in anchoring sperm head to the tail. Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope.
Bpifb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028983BPI fold-containing family B member 2.
Bpifa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028984BPI fold-containing family A member 3.
Bpifa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028985BPI fold-containing family A member 1; Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC) (By similarity). Plays a role in th [...]
Bpifa5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000028986BPI fold-containing family A member 5; May play a role in innate immunity in the oral cavity. Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
Fam210b protein networkhttps://string-db.org/network/10090.ENSMUSP00000028995Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cell [...]
Aurka protein networkhttps://string-db.org/network/10090.ENSMUSP00000028997Aurora kinase A; Mitotic serine/threonine kinase that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays [...]
Pkia protein networkhttps://string-db.org/network/10090.ENSMUSP00000028999cAMP-dependent protein kinase inhibitor alpha; Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme af [...]
Stmn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029002Stathmin-2; Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negati [...]
Rtf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029005Replication termination factor 2; Replication termination factor which is a component of the elongating replisome. Required for ATR pathway signaling upon DNA damage and has a positive activity d [...]
Fam209 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029007Family with sequence similarity 209.
Rae1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029013mRNA export factor; Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cyt [...]
Pck1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029017Phosphoenolpyruvate carboxykinase, cytosolic [GTP]; Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low gluco [...]
Zbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029018Z-DNA-binding protein 1; Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathoge [...]
1700021F07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000029023Uncharacterized protein C20orf85 homolog.
Rab22a protein networkhttps://string-db.org/network/10090.ENSMUSP00000029024Ras-related protein Rab-22A; Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF- mediated en [...]
Edn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029030Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family.
Pmp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029034Myelin P2 protein; May play a role in lipid transport protein in Schwann cells. May bind cholesterol (By similarity).
Fabp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029038Fatty acid-binding protein 9; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Fabp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029041Fatty acid-binding protein, adipocyte; Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cogna [...]
Fabp12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029043Fatty acid-binding protein 12; May play a role in lipid transport; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Fabp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029046Fatty acid-binding protein 5; Intracellular carrier for long-chain fatty acids and related active lipids, such as the endocannabinoid, that regulates the metabolism and actions of the ligands the [...]
Snx16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029047Sorting nexin-16; May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome [...]
Chmp4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000029049Charged multivesicular body protein 4c; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation [...]
Ptpn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029053Tyrosine-protein phosphatase non-receptor type 1; Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/ [...]
Atp9a protein networkhttps://string-db.org/network/10090.ENSMUSP00000029060Probable phospholipid-transporting ATPase IIA.
Sall4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029061Sal-like protein 4; Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells; Belongs to the sal C2H2-type zinc-finger protein family.
E2f5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029069Transcription factor E2F5; Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate [...]
Car13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029071Carbonic anhydrase 13; Reversible hydration of carbon dioxide.
Dok5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029075Docking protein 5; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in [...]
Car3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029076Carbonic anhydrase 3; Reversible hydration of carbon dioxide.
Car2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029078Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villou [...]
Cypt12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029080Cysteine-rich perinuclear theca 12.
Psma7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029082Proteasome subunit alpha type-7; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles w [...]
Ntsr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029084Neurotensin receptor type 1; G-protein coupled receptor for the tridecapeptide neurotensin (NTS). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenge [...]
Mrgbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000029085MRG/MORF4L-binding protein; Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal [...]
Ogfr protein networkhttps://string-db.org/network/10090.ENSMUSP00000029087Opioid growth factor receptor; Receptor for opioid growth factor (OGF), also known as Met- enkephalin. Seems to be involved in growth regulation (By similarity).
Arfgap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029092ADP-ribosylation factor GTPase-activating protein 1; GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes [...]
Zgpat protein networkhttps://string-db.org/network/10090.ENSMUSP00000029105Zinc finger CCCH-type with G patch domain-containing protein; Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting t [...]
Zbtb46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029106Zinc finger and BTB domain-containing protein 46; Functions as a transcriptional repressor for PRDM1.
Pcmtd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029116Protein-L-isoaspartate O-methyltransferase domain-containing protein 2.
Raly protein networkhttps://string-db.org/network/10090.ENSMUSP00000029120RNA-binding protein Raly; RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is requi [...]
a protein networkhttps://string-db.org/network/10090.ENSMUSP00000029123Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-reg [...]
Armc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029125Armadillo repeat-containing protein 1.
Map1lc3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000029128Microtubule-associated proteins 1A/1B light chain 3A; Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Whereas LC3s are involved in elongation of the pha [...]
Ggt7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029131Glutathione hydrolase 7 heavy chain; Cleaves glutathione conjugates.
Acss2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029135Acetyl-coenzyme A synthetase, cytoplasmic; Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate but can also utilize propionate with a much lower [...]
Trim55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029139Tripartite motif-containing 55.
Procr protein networkhttps://string-db.org/network/10090.ENSMUSP00000029140Endothelial protein C receptor; Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulatio [...]
Mmp24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029141Processed matrix metalloproteinase-24; Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. Involved i [...]
Eif6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029142Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Beh [...]
Fam83c protein networkhttps://string-db.org/network/10090.ENSMUSP00000029143Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family.
Nfs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029147Cysteine desulfurase, mitochondrial; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters. May be involved [...]
Epb41l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029155Band 4.1-like protein 1; May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channel [...]
Aar2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029158Protein AAR2 homolog; Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing. Belongs to the AAR2 family.
Sla2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029164Src-like-adapter 2; Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. May ac [...]
Rab5if protein networkhttps://string-db.org/network/10090.ENSMUSP00000029165Respirasome Complex Assembly Factor 1; Acts as an assembly factor for mitochondrial respiratory complexes.
Rbl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029170Retinoblastoma-like protein 1; Key regulator of entry into cell division (By similarity). Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particu [...]
Ghrh protein networkhttps://string-db.org/network/10090.ENSMUSP00000029172Somatoliberin; GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone; Belongs to the glucagon family.
Ctnnbl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029178Beta-catenin-like protein 1; Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May induce apoptosis (By similar [...]
Tti1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029179TELO2-interacting protein 1 homolog; Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related [...]
Rprd1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000029180Regulation of nuclear pre-mRNA domain-containing protein 1B; Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and partici [...]
Fam83d protein networkhttps://string-db.org/network/10090.ENSMUSP00000029183Protein FAM83D; Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the [...]
Dhx35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029186DEAH (Asp-Glu-Ala-His) box polypeptide 35.
Ccn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029188CCN family member 5; May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, i [...]
Skil protein networkhttps://string-db.org/network/10090.ENSMUSP00000029194Ski-like protein; May have regulatory role in cell division or differentiation in response to extracellular signals; Belongs to the SKI family.
Slc2a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029196Solute carrier family 2, facilitated glucose transporter member 10; Facilitative glucose transporter required for the development of the cardiovascular system.
Zmat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029199Zinc finger matrin-type protein 3; Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regul [...]
Pik3ca protein networkhttps://string-db.org/network/10090.ENSMUSP00000029201Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol [...]
Slc13a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029208Solute carrier family 13 member 3; High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-6 carbon atoms, including succinate, alpha-ketoglutarate and N-acetyl [...]
Ocstamp protein networkhttps://string-db.org/network/10090.ENSMUSP00000029213Osteoclast stimulatory transmembrane protein; Probable cell surface receptor that plays a role in cellular fusion and cell differentiation. Cooperates with DCSTAMP in modulating cell-cell fusion [...]
Actl6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000029214Actin-like protein 6A; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remode [...]
Ccdc39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029222Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby [...]
Slc2a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029240Solute carrier family 2, facilitated glucose transporter member 2; Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer [...]
Lrrc34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029252Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression o [...]
Sec62 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029256Translocation protein SEC62; Mediates post-translational transport of precursor polypeptides across endoplasmic reticulum (ER). Proposed to act as a targeting receptor for small presecretory prot [...]
Atp11b protein networkhttps://string-db.org/network/10090.ENSMUSP00000029257Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
Mccc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029259Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA t [...]
Anxa5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029266Annexin A5; This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade; Belongs to the [...]
Exosc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029269Exosome complex component RRP45; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrad [...]
Ccna2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029270Cyclin-A2; Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine kinase holoenzyme complexes with the [...]
Trpc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029271Short transient receptor potential channel 3; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger s [...]
Il2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029275Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune re [...]
Slc7a11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029297Cystine/glutamate transporter; Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.
Naa15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029303N-alpha-acetyltransferase 15, NatA auxiliary subunit; Auxillary subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT [...]
Stoml3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029307Stomatin-like protein 3; Required for the function of many mechanoreceptors. Modulate mechanotransduction channels and acid-sensing ion channels (ASIC) proteins. Potentiates PIEZO1 and PIEZO2 fun [...]
Trpc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029311Short transient receptor potential channel 4; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger s [...]
Exosc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029316Exosome complex component RRP43; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrad [...]
Aadac protein networkhttps://string-db.org/network/10090.ENSMUSP00000029325Arylacetamide deacetylase; Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stor [...]
Sucnr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029326Succinate receptor 1; Receptor for succinate; Belongs to the G-protein coupled receptor 1 family.
P2ry1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029331P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, [...]
Dhx36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029336ATP-dependent DNA/RNA helicase DHX36; Multifunctional ATP-dependent helicase that unwinds G- quadruplex (G4) structures. Plays a role in many biological processes such as genomic integrity, gene [...]
Mfsd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029344Major facilitator superfamily domain-containing protein 1.
Schip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029346Schwannomin-interacting protein 1; Belongs to the SCHIP1 family.
Ppm1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000029355Protein phosphatase 1L; Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK [...]
Nmd3 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002935860S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.
Bche protein networkhttps://string-db.org/network/10090.ENSMUSP00000029367Cholinesterase; Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters; Belongs to the typ [...]
Sohlh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029369Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2; Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermat [...]
Smad9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029371Mothers against decapentaplegic homolog 9; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor- regulated SMAD (R-SMAD). Has been [...]
Nbea protein networkhttps://string-db.org/network/10090.ENSMUSP00000029374Neurobeachin; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins. May ha [...]
Tm4sf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029377Transmembrane 4 L6 family member 4; Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation (By similarity); Belongs to th [...]
Ppid protein networkhttps://string-db.org/network/10090.ENSMUSP00000029382Peptidyl-prolyl cis-trans isomerase D; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Proposed to act [...]
Serp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029385Stress-associated endoplasmic reticulum protein 1; Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against [...]
Etfdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000029386Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Accepts electrons from ETF and reduces ubiquinone.
Eif2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000029387Eukaryotic translation initiation factor 2A, N-terminally processed; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methio [...]
4930579G24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000029388Uncharacterized protein C4orf46 homolog.
Slc33a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029402Acetyl-coenzyme A transporter 1; Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides. Negatively regulates BMP signaling (By similarity); Belongs to the SLC33A transporter [...]
Gmps protein networkhttps://string-db.org/network/10090.ENSMUSP00000029405GMP synthase [glutamine-hydrolyzing]; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a [...]
Vmn2r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029406Vomeronasal type-2 receptor 1; Putative pheromone receptor; Belongs to the G-protein coupled receptor 3 family.
Ssr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029414Translocon-associated protein subunit gamma; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins; B [...]
Ccnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029416Cyclin-L1; Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs). May play a role in the regulation of RNA polymerase II (pol II). Inhibited by the CDK-spec [...]
Veph1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029419Ventricular zone-expressed PH domain-containing protein 1; Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumula [...]
Ptx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029421Pentraxin-related protein PTX3; Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self- components and female fertility.
Shox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029422Short stature homeobox protein 2; May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure fo [...]
Serpini1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029423Neuroserpin; Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for [...]
Wnt2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000029429Protein Wnt-2b; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a redundant role in emb [...]
Ptpn22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029433Tyrosine-protein phosphatase non-receptor type 22; Acts as negative regulator of T-cell receptor (TCR) signaling by direct dephosphorylation of the Src family kinases LCK and FYN, ITAMs of the TC [...]
Dclre1b protein networkhttps://string-db.org/network/10090.ENSMUSP000000294355' exonuclease Apollo; 5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-jo [...]
Olfml3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029440Olfactomedin-like protein 3; Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) a [...]
Syt10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029441Synaptotagmin-10; Ca(2+) sensor specifically required for the Ca(2+)-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required fo [...]
Trim33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029444E3 ubiquitin-protein ligase TRIM33; Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway (By similarity). [...]
Nras protein networkhttps://string-db.org/network/10090.ENSMUSP00000029445GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.
Csde1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029446Cold shock domain-containing protein E1; RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation [...]
Sike1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029447Suppressor of IKBKE 1; Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3- mediated activation of interferon-stimulate [...]
Sycp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029448Synaptonemal complex protein 1; Major component of the transverse filaments of synaptonemal complexes, formed between homologous chromosomes during meiotic prophase. Required for normal assembly [...]
Tshb protein networkhttps://string-db.org/network/10090.ENSMUSP00000029450Thyrotropin subunit beta; Indispensable for the control of thyroid structure and metabolism.
Tspan2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029451Tetraspanin-2; May play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature she [...]
Vangl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029453Vang-like protein 1.
Casq2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029454Calsequestrin-2; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic r [...]
Cd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029456T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the [...]
Gdap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029459Ganglioside-induced differentiation-associated protein 2; Belongs to the GDAP2 family.
Tbx15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029462T-box transcription factor TBX15; Probable transcriptional regulator involved in the development of the skeleton of the limb, vertebral column and head. Acts by controlling the number of mesenchy [...]
Hsd3b6 protein networkhttps://string-db.org/network/10090.ENSMUSP000000294633 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 6; 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxid [...]
Hao2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029464Hydroxyacid oxidase 2; Has 2-hydroxyacid oxidase activity. Most active on medium- chain substrates; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
Reg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029469Regenerating islet-derived protein 4; Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be inv [...]
Sec22b protein networkhttps://string-db.org/network/10090.ENSMUSP00000029476Vesicle-trafficking protein SEC22b; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the [...]
Slc25a24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029477Calcium-binding mitochondrial carrier protein SCaMC-1; Calcium-dependent mitochondrial solute carrier. Mediates the reversible, electroneutral exchange of Mg-ATP or Mg-ADP against phosphate ions, [...]
Slc25a54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029478Solute carrier family 25, member 54; Belongs to the mitochondrial carrier (TC 2.A.29) family.
Prpf38b protein networkhttps://string-db.org/network/10090.ENSMUSP00000029480Pre-mRNA-splicing factor 38B; May be required for pre-mRNA splicing; Belongs to the PRP38 family.
Gpsm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029482G-protein-signaling modulator 2; Plays an important role in mitotic spindle pole organization via its interaction with NUMA1. Required for cortical dynein-dynactin complex recruitment during meta [...]
1700013F07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000029485Protein C1orf194 homolog; May play an important role for the maintenance of myelin-axon integrity. May affect intracellular Ca(2+) homeostasis (By similarity).
Gstm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029489Glutathione S-transferase, mu 4.
Ahcyl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029490S-adenosylhomocysteine hydrolase-like protein 1; Multifaceted cellular regulator which coordinates several essential cellular functions including regulation of epithelial HCO3(-) and fluid secret [...]
Slc16a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029502Monocarboxylate transporter 5; Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-cha [...]
Cym protein networkhttps://string-db.org/network/10090.ENSMUSP00000029504Gene model 131, (NCBI); Belongs to the peptidase A1 family.
Chil6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029510cDNA sequence BC051070; Belongs to the glycosyl hydrolase 18 family.
S100a11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029515Protein S100-A11; Facilitates the differentiation and the cornification of keratinocytes.
Tchhl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029516Trichohyalin-like protein 1; Belongs to the S-100 family.
Lce1m protein networkhttps://string-db.org/network/10090.ENSMUSP00000029520Late cornified envelope 1M.
Crct1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029521Cysteine-rich C-terminal 1.
Lce1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000029524Late cornified envelope 1D.
Lce1g protein networkhttps://string-db.org/network/10090.ENSMUSP00000029527Late cornified envelope 1G.
Lce1a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029530Late cornified envelope 1A2.
Lce1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000029531Late cornified envelope 1B.
Sprr2j-ps protein networkhttps://string-db.org/network/10090.ENSMUSP00000029533Putative small proline-rich protein 2J; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to [...]
Lelp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029535Late cornified envelope-like proline-rich protein 1; Belongs to the cornifin (SPRR) family.
Npr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029540Atrial natriuretic peptide receptor 1; Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in c [...]
Slc27a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029541Solute carrier family 27 member 3; Has acyl-CoA ligase activity for long-chain and very-long- chain fatty acids. Does not exhibit fatty acid transport activity.
Ints3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029542Integrator complex subunit 3; Component of the Integrator (INT) complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent [...]
Crtc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029545CREB-regulated transcription coactivator 2; Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coa [...]
Jtb protein networkhttps://string-db.org/network/10090.ENSMUSP00000029546Protein JTB; Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that ac [...]
Creb3l4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029547Processed cyclic AMP-responsive element-binding protein 3-like protein 4; Transcriptional activator that may play a role in the unfolded protein response of the testis. Proposed to be involved in [...]
Nup210l protein networkhttps://string-db.org/network/10090.ENSMUSP00000029548Nuclear pore membrane glycoprotein 210-like.
1700094D03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000029551Uncharacterized protein C1orf189 homolog.
Il6ra protein networkhttps://string-db.org/network/10090.ENSMUSP00000029559Interleukin-6 receptor subunit alpha; Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL [...]
Chrnb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029562Neuronal acetylcholine receptor subunit beta-2; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-cond [...]
Pmvk protein networkhttps://string-db.org/network/10090.ENSMUSP00000029564Phosphomevalonate kinase.
Slc50a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029565Sugar transporter SWEET1; Mediates sugar transport across membranes (By similarity). May regulate the expression of RAG1 a gene involved in V(D)J recombination.
Efna1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029566Ephrin-A1, secreted form; Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular [...]
Tmem144 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029568Transmembrane protein 144.
Slc35a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029569UDP-N-acetylglucosamine transporter; Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter in the Golgi apparatus. May supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransfe [...]
Mfsd14a protein networkhttps://string-db.org/network/10090.ENSMUSP00000029570Hippocampus abundant transcript 1 protein.
Lrrc39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029573Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via [...]
Vcam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029574Vascular cell adhesion protein 1; Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha- 4/beta-1 (ITGA4/ITGB1) on leukocyt [...]
Extl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029575Exostosin-like 2; Glycosyltransferase required for the biosynthesis of heparan- sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked [...]
Neurog2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029587Neurogenin-2; Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'- CANNTG-3').
Larp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029588La-related protein 7; Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b [...]
1700006A11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000029598RIKEN cDNA 1700006A11 gene.
Prss12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029603Neurotrypsin; Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
Hadh protein networkhttps://string-db.org/network/10090.ENSMUSP00000029610Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3- hydroxybutyryl-Co [...]
Lef1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029611Lymphoid enhancer-binding factor 1; Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differenti [...]
Tlr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029623Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the in [...]
Mcub protein networkhttps://string-db.org/network/10090.ENSMUSP00000029624Calcium uniporter regulatory subunit MCUb, mitochondrial; Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into t [...]
Sfrp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029625Secreted frizzled-related protein 2; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell gr [...]
Casp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029626Caspase-6 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes [...]
Pla2g12a protein networkhttps://string-db.org/network/10090.ENSMUSP00000029629Group XIIA secretory phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl [...]
Lrat protein networkhttps://string-db.org/network/10090.ENSMUSP00000029632Lecithin retinol acyltransferase; Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters (By similarity). Retinyl esters a [...]
Npy2r protein networkhttps://string-db.org/network/10090.ENSMUSP00000029633Neuropeptide Y receptor type 2; Receptor for neuropeptide Y and peptide YY; Belongs to the G-protein coupled receptor 1 family.
Gucy1b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029635Guanylate cyclase soluble subunit beta-1; Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.
Snx7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029639Sorting nexin-7; May be involved in several stages of intracellular trafficking; Belongs to the sorting nexin family.
Asic5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029641Acid-sensing ion channel 5; Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium and lithium, and i [...]
Gar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029643H/ACA ribonucleoprotein complex subunit 1; Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes p [...]
Ppa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029644Inorganic pyrophosphatase 2, mitochondrial; Hydrolyzes inorganic pyrophosphate. This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organizati [...]
Tdo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029645Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyze [...]
Ctso protein networkhttps://string-db.org/network/10090.ENSMUSP00000029649Cathepsin O; Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover.
Ints12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029650Integrator complex subunit 12; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'- box-dependent processing. The Int [...]
Gstcd protein networkhttps://string-db.org/network/10090.ENSMUSP00000029651Glutathione S-transferase C-terminal domain-containing protein; Belongs to the GSTCD family.
Pdgfc protein networkhttps://string-db.org/network/10090.ENSMUSP00000029652Platelet-derived growth factor C, receptor-binding form; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and ch [...]
Egf protein networkhttps://string-db.org/network/10090.ENSMUSP00000029653Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimul [...]
Glrb protein networkhttps://string-db.org/network/10090.ENSMUSP00000029654Glycine receptor subunit beta; Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride chann [...]
Enpep protein networkhttps://string-db.org/network/10090.ENSMUSP00000029658Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.
Alpk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029662Alpha-protein kinase 1; Serine/threonine-protein kinase that detects bacterial pathogen-associated molecular pattern metabolites (PAMPs) and initiates an innate immune response, a critical step f [...]
Aimp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029663Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase [...]
Dkk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029665Dickkopf-related protein 2; Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes inte [...]
Papss1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029666Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1; Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. T [...]
Ptgfr protein networkhttps://string-db.org/network/10090.ENSMUSP00000029670Prostaglandin F2-alpha receptor; Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second mes [...]
Ifi44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029671Interferon-induced protein 44; This protein aggregates to form microtubular structures. Belongs to the IFI44 family.
Efna3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029673Ephrin-A3; Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial [...]
Efna4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029674Ephrin-A4; Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial [...]
Adam15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029676Disintegrin and metalloproteinase domain-containing protein 15; Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both h [...]
Cks1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000029679Cyclin-dependent kinases regulatory subunit 1; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function; Belongs to the CKS family.
Thbs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029682Thrombospondin-3; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.
Hcn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029686Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3; Hyperpolarization-activated potassium channel. May also facilitate the permeation of sodium ions. Belongs to the po [...]
Rit1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029692GTP-binding protein Rit1; Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation. Involved i [...]
Arhgef2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029694Rho guanine nucleotide exchange factor 2; Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendr [...]
Khdc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029696KH homology domain-containing protein 4; RNA-binding protein involved in pre-mRNA splicing. Interacts with the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome. Involved [...]
Lamtor2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029698Ragulator complex protein LAMTOR2; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth [...]
Lmna protein networkhttps://string-db.org/network/10090.ENSMUSP00000029699Prelamin-A/C; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelop [...]
Sema4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000029700Semaphorin-4A; Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. Regulates glutamatergic and GABAergic synapse development. Promotes [...]
Naxe protein networkhttps://string-db.org/network/10090.ENSMUSP00000029708NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisi [...]
Insrr protein networkhttps://string-db.org/network/10090.ENSMUSP00000029711Insulin receptor-related protein alpha chain; Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an int [...]
Ntrk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029712High affinity nerve growth factor receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferati [...]
Cd1d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029717Antigen-presenting glycoprotein CD1d1; Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T- cells.
Dclk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029719Serine/threonine-protein kinase DCLK2; Protein kinase with a significantly reduced Ca(2+)+/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-re [...]
Rps3a1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002972240S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3.
Chd1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000029730Chromodomain-helicase-DNA-binding protein 1-like; DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-r [...]
Gpr89 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029738Golgi pH regulator; Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance.
Rnf115 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029740E3 ubiquitin-protein ligase RNF115; E3 ubiquitin-protein ligase that mediates E2-dependent, 'Lys- 48'- and/or 'Lys-63'-linked polyubiquitination of substrates and may play a role in diverse biolo [...]
Nudt17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029742Nucleoside diphosphate-linked moiety X motif 17; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
Fcgr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029748High affinity immunoglobulin gamma Fc receptor I; High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
Tars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029752Threonine--tRNA ligase, mitochondrial; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the [...]
Hormad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029754HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks ( [...]
Mettl14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029759N6-adenosine-methyltransferase non-catalytic subunit; The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and [...]
Myoz2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029761Myozenin-2; Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin [...]
Bcar3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029766Breast cancer anti-estrogen resistance protein 3 homolog; Acts as an adapter protein downstream of several growth factor receptors to promote cell proliferation, migration, and redistribution of [...]
Gclm protein networkhttps://string-db.org/network/10090.ENSMUSP00000029769Glutamate--cysteine ligase regulatory subunit; Belongs to the aldo/keto reductase family. Glutamate-- cysteine ligase light chain subfamily.
Abcd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029770ATP-binding cassette sub-family D member 3; Probable transporter involved in the transport of branched- chain fatty acids and C27 bile acids into the peroxisome; the latter function is a crucial [...]
F3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029771Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a ro [...]
Cnn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029773Calponin-3; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropom [...]
Ptbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029780Polypyrimidine tract-binding protein 2; RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific m [...]
Riiad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029785RIIa domain-containing protein 1.
Mrpl9 protein networkhttps://string-db.org/network/10090.ENSMUSP0000002978639S ribosomal protein L9, mitochondrial; Belongs to the bacterial ribosomal protein bL9 family.
Them5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029794Acyl-coenzyme A thioesterase THEM5; Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleoyl-CoA and other unsaturated long-c [...]
Rorc protein networkhttps://string-db.org/network/10090.ENSMUSP00000029795Nuclear receptor ROR-gamma; Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequenc [...]
Tspan5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029800Tetraspanin-5; Regulates ADAM10 maturation and trafficking to the cell surface. Promotes ADAM10-mediated cleavage of CD44 (By similarity).
Eif4e protein networkhttps://string-db.org/network/10090.ENSMUSP00000029803Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome bi [...]
Metap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029804Methionine aminopeptidase 1; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence [...]
Dapp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029806Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.
Nfkb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029812Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are in [...]
Manba protein networkhttps://string-db.org/network/10090.ENSMUSP00000029814Beta-mannosidase; Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides; Belongs to the glycosyl hydrolase 2 f [...]
Cisd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029815CDGSH iron-sulfur domain-containing protein 2; Regulator of autophagy that contributes to antagonize BECN1- mediated cellular autophagy at the endoplasmic reticulum. Participates in the interacti [...]
Tacr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029822Neuromedin-K receptor; This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messeng [...]
Lrriq3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029833Leucine-rich repeat and IQ domain-containing protein 3.
Uox protein networkhttps://string-db.org/network/10090.ENSMUSP00000029837Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
Rpf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029838Ribosome production factor 1; May be required for ribosome biogenesis.
Spata1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029839Spermatogenesis-associated protein 1.
Bcl10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029842B-cell lymphoma/leukemia 10; Involved in adaptive immune response. Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between ups [...]
Ddah1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029845N(G),N(G)-dimethylarginine dimethylaminohydrolase 1; Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)- monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in [...]
Ccn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029846CCN family member 1; Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up- regulating, in skin fibroblasts, the expression of a n [...]
Col24a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029848Collagen alpha-1(XXIV) chain; Involved in osteoblast differentiation. Belongs to the fibrillar collagen family.
Cryz protein networkhttps://string-db.org/network/10090.ENSMUSP00000029850Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequ [...]
Trp53inp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029865Tumor protein p53-inducible nuclear protein 1; Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a [...]
Cdh17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029871Cadherin-17; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the [...]
Pip4p2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029875Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P) (By [...]
Calb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029876Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
Decr1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000298772,4-dienoyl-CoA reductase, mitochondrial; Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-num [...]
Nbn protein networkhttps://string-db.org/network/10090.ENSMUSP00000029879Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in d [...]
Mmp16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029881Matrix metalloproteinase-16; Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matr [...]
Cpne3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029885Copine-3; Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation; Belongs to the copine family.
Rmdn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029888Regulator of microtubule dynamics protein 1; Belongs to the RMDN family.
Tmem68 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029891Transmembrane protein 68.
Atp6v0d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029900V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryot [...]
Cyp7a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029905Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecu [...]
Ubxn2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000029907UBX domain-containing protein 2B; Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their r [...]
Faxc protein networkhttps://string-db.org/network/10090.ENSMUSP00000029908Failed axon connections homolog; May play a role in axonal development; Belongs to the FAX family.
Coq3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029909Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-bi [...]
Nsmaf protein networkhttps://string-db.org/network/10090.ENSMUSP00000029910Protein FAN; Couples the p55 TNF-receptor (TNF-R55 / TNFR1) to neutral sphingomyelinase (N-SMASE). Specifically binds to the N-smase activation domain of TNF-R55. May regulate ceramide production [...]
Pnisr protein networkhttps://string-db.org/network/10090.ENSMUSP00000029911Arginine/serine-rich protein PNISR; Belongs to the splicing factor SR family.
Sdcbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000029912Syntenin-1; Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenes [...]
Tstd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029915Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3.
Clca1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029919Calcium-activated chloride channel regulator 1; May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cysti [...]
Ndufaf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029925NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4; May be involved in cell proliferation and survival of hormone-dependent tumor cells. Involved in the assembly of mitochondria [...]
Spaca1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029927Sperm acrosome membrane-associated protein 1; Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis. Important for male fertility.
Clca3a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029929Chloride channel calcium activated 2.
Gbp2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000029936Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus (By similarity). Promotes oxidative killing and deliver [...]
Gtf2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000029938Transcription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formati [...]
Gabrr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029947Gamma-aminobutyric acid receptor subunit rho-1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor an [...]
Bmpr1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000029948Bone morphogenetic protein receptor type-1B; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phospho [...]
Casp8ap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029950CASP8-associated protein 2; Participates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF- [...]
1700009N14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000029955GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin co [...]
Epha7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029964Ephrin type-A receptor 7; Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling [...]
Rars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029968Probable arginine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
Slc35a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029970CMP-sialic acid transporter; Transports CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function. Efficient CMP-sialic acid uptake depends on the presence of free [...]
Cfap206 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029971Cilia- and flagella-associated protein 206; May regulate cilium motility through its role in the assembly of the axonemal radial spokes.
Cga protein networkhttps://string-db.org/network/10090.ENSMUSP00000029975Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropi [...]
Aldob protein networkhttps://string-db.org/network/10090.ENSMUSP00000029987Fructose-bisphosphate aldolase B.
Ppp3r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000029991Calcineurin subunit B type 2; Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
Polr1e protein networkhttps://string-db.org/network/10090.ENSMUSP00000029999DNA-directed RNA polymerase I subunit RPA49; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
Exosc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030003Exosome complex component RRP40; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrad [...]
Abca1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030010Phospholipid-transporting ATPase ABCA1; Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of AT [...]
Xpa protein networkhttps://string-db.org/network/10090.ENSMUSP00000030013DNA repair protein complementing XP-A cells homolog; Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the t [...]
Ncbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030014Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA [...]
Nans protein networkhttps://string-db.org/network/10090.ENSMUSP00000030018Sialic acid synthase; Produces N-acetylneuraminate-9-phosphate (Neu5Ac-9-P) from N- acetylmannosamine 6-phosphate. Has no detectable activity towards N- acetylmannosamine or mannose 6-phosphate.
Nr4a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030025Nuclear receptor subfamily 4 group A member 3; Transcriptional activator that binds to regulatory elements in promoter regions in a cell- and response element (target)-specific manner. Induces ge [...]
Erp44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030028Endoplasmic reticulum resident protein 44; Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. In [...]
Invs protein networkhttps://string-db.org/network/10090.ENSMUSP00000030029Inversin; Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt path [...]
Tmeff1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030032Tomoregulin-1; May inhibit NODAL and BMP signaling during neural patterning. Belongs to the tomoregulin family.
Cavin4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030033Caveolae-associated protein 4; Modulates the morphology of formed caveolae in cardiomyocytes, but is not required for caveolar formation. Facilitates the recruitment of MAPK1/3 to caveolae within [...]
Brinp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030036BMP/retinoic acid-inducible neural-specific protein 1; Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type [...]
Fmn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030039Formin-2; Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE [...]
Ambp protein networkhttps://string-db.org/network/10090.ENSMUSP00000030041Inter-alpha-trypsin inhibitor light chain; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization (By similarity); [...]
Kif12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030042Kinesin-like protein KIF12.
Orm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030044Alpha-1-acid glycoprotein 1; Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain (By similarity). Appears to function in modulating [...]
Tnfsf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030047Tumor necrosis factor ligand superfamily member 8; Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
Txn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030051Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity [...]
Ptgr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030069Prostaglandin reductase 1; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha. Catalyzes [...]
Ugcg protein networkhttps://string-db.org/network/10090.ENSMUSP00000030074Ceramide glucosyltransferase; Catalyzes at the cytosolic surface of the Golgi, the initial step of the glucosylceramide-based glycosphingolipid/GSL synthetic pathway, the transfer of glucose from [...]
Hsdl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030078Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Snx30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030080Sorting nexin-30; May be involved in several stages of intracellular trafficking.
Slc46a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030081Thymic stromal cotransporter protein; May act as a transporter.
Bspry protein networkhttps://string-db.org/network/10090.ENSMUSP00000030088B box and SPRY domain-containing protein; May regulate epithelial calcium transport by inhibiting TRPV5 activity.
Pole3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030091DNA polymerase epsilon subunit 3; Accessory component of the DNA polymerase epsilon complex (By similarity). Participates in DNA repair and in chromosomal DNA replication (By similarity). Forms a [...]
Kdm4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000030102Lysine-specific demethylase 4C; Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylat [...]
Dmac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030103Distal membrane-arm assembly complex protein 1; Required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of [...]
Zdhhc21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030110Probable palmitoyltransferase ZDHHC21; Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intra [...]
Smu1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030117WD40 repeat-containing protein SMU1, N-terminally processed; Involved in pre-mRNA splicing as a component of the spliceosome (By similarity). Regulates alternative splicing of the HSPG2 pre-mRNA [...]
B4galt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030121Processed beta-1,4-galactosyltransferase 1; The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-ty [...]
Spink4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030122Serine protease inhibitor Kazal-type 4.
Tal2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030124T-cell acute lymphocytic leukemia protein 2 homolog.
Bag1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030125BAG family molecular chaperone regulator 1; Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 p [...]
Tmem38b protein networkhttps://string-db.org/network/10090.ENSMUSP00000030127Trimeric intracellular cation channel type B; Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions [...]
Chmp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030128Charged multivesicular body protein 5; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodie [...]
Rad23b protein networkhttps://string-db.org/network/10090.ENSMUSP00000030134UV excision repair protein RAD23 homolog B; Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultan [...]
Aqp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030136Aquaporin-7; Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH. The channel is also permeable to urea (By similarity). Plays an important role in body [...]
Nol6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030138Nucleolar protein 6; Belongs to the NRAP family.
Elp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030140Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in trans [...]
Epb41l4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000030142Band 4.1-like protein 4B; Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18. Involved in the regulation of the circumferential actomyosin belt in epithelial cells. [...]
Ubap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030143Ubiquitin-associated protein 2.
Dcaf12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030145DDB1- and CUL4-associated factor 12; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat DCAF12 family.
1110017D15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000030152Spermatid-specific manchette-related protein 1; May be involved in differentiation or function of ciliated cells (By similarity). May play a role in spermatogenesis. Belongs to the SMRP1 family.
Nudt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030154Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Asymmetrically hydrolyzes Ap4A to yield AMP and ATP. Plays a major role in maintaining homeostasis (By similarity).
Dctn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030158Dynactin subunit 3; Together with dynein may be involved in spindle assembly and cytokinesis.
1700022I11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000030163Uncharacterized protein C9orf131 homolog.
Vcp protein networkhttps://string-db.org/network/10090.ENSMUSP00000030164Transitional endoplasmic reticulum ATPase; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional end [...]
Fancg protein networkhttps://string-db.org/network/10090.ENSMUSP00000030165Fanconi anemia group G protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair [...]
Stoml2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030169Stomatin-like protein 2, mitochondrial; Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enric [...]
Unc13a protein networkhttps://string-db.org/network/10090.ENSMUSP00000030170Protein unc-13 homolog A; Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Involved in neurotransmitter release by acting in synapt [...]
Cd72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030179B-cell differentiation antigen CD72; Plays a role in B-cell proliferation and differentiation.
Sit1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030180Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.
Ccdc107 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030181Coiled-coil domain-containing protein 107.
Car9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030183Carbonic anhydrase 9; Reversible hydration of carbon dioxide. Participates in pH regulation (By similarity).
Tln1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030187Talin-1; Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact an [...]
Gba2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030189Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. Glucosylceramides are membrane glycosph [...]
Npr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030191Atrial natriuretic peptide receptor 2; Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation o [...]
Hint2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030192Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similari [...]
Reck protein networkhttps://string-db.org/network/10090.ENSMUSP00000030198Reversion-inducing cysteine-rich protein with Kazal motifs; Functions together with ADGRA2 to enable brain endothelial cells to selectively respond to Wnt7 signals (WNT7A or WNT7B). Plays a key r [...]
Gne protein networkhttps://string-db.org/network/10090.ENSMUSP00000030201Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for nor [...]
Glipr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030202Golgi-associated plant pathogenesis-related protein 1; Belongs to the CRISP family.
Snapc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030206snRNA-activating protein complex subunit 3; Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence elem [...]
Psip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030207PC4 and SFRS1-interacting protein; Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulati [...]
Sh3gl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030212Endophilin-A1; Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to m [...]
Saxo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030216Stabilizer of axonemal microtubules 1.
Hacd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030221Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, [...]
Prkaa2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000302435'-AMP-activated protein kinase catalytic subunit alpha-2; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular e [...]
4921539E11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000030245Uncharacterized protein C1orf141 homolog.
Leprot protein networkhttps://string-db.org/network/10090.ENSMUSP00000030254Leptin receptor gene-related protein; Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin. Negatively regulates growth hormone (GH) receptor [...]
Cachd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030257VWFA and cache domain-containing protein 1; May regulate voltage-dependent calcium channels.
2610528J11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000030261Type III endosome membrane protein TEMP; May be involved in membrane trafficking between endosomes and plasma membrane.
St3gal3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030263CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase; Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4- GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alph [...]
Dph2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000302652-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation el [...]
B4galt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030266Beta-1,4-galactosyltransferase 2; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce la [...]
Slc6a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030269Sodium- and chloride-dependent glycine transporter 1; Terminates the action of glycine by its high affinity sodium- dependent reuptake into presynaptic terminals. May play a role in regulation of [...]
Bend5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030274BEN domain-containing protein 5; Acts as a transcriptional repressor.
Atg4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000030279Cysteine protease ATG4C; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to [...]
Angptl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030280Angiopoietin-related protein 3; Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to eit [...]
Rnf11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030284RING finger protein 11; Essential component of a ubiquitin-editing protein complex, comprising also TNFAIP3, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways [...]
Calr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030285Calreticulin.
Dock7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030286Dedicator of cytokinesis protein 7; Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a [...]
Usp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030289Ubiquitin carboxyl-terminal hydrolase 1; Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2. Also involved in PCNA- mediated translesion synthesis [...]
Txndc12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030296Thioredoxin domain-containing protein 12; Possesses significant protein thiol-disulfide oxidase activity.
Cyp2j5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030299Cytochrome P450 2J5.
Cyp2j6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030303Cytochrome P450 2J6.
Cyp2j13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030305Cytochrome P450, family 2, subfamily j, polypeptide 13; Belongs to the cytochrome P450 family.
Hook1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030306Protein Hook homolog 1; Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton. C [...]
Eqtn protein networkhttps://string-db.org/network/10090.ENSMUSP00000030309Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis.
Ift74 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030311Intraflagellar transport protein 74 homolog; Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of [...]
Caap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030313Caspase activity and apoptosis inhibitor 1; Anti-apoptotic protein that modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop.
Pum1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030315Pumilio homolog 1; Sequence-specific RNA-binding protein that acts as a post- transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Resp [...]
Pdpn protein networkhttps://string-db.org/network/10090.ENSMUSP00000030317Podoplanin; Mediates effects on cell migration and adhesion through its different partners. During development plays a role in blood and lymphatic vessels separation by binding CLEC1B, triggering [...]
Cc2d1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000030320Coiled-coil and C2 domain-containing protein 1B; Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells; Belongs [...]
1700012P22Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000030323Uncharacterized protein C1orf158 homolog.
Pramef12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030326PRAME family member 12.
Aadacl4fm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030328Arylacetamide deacetylase-like 4.
Gpx7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030332Glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects agai [...]
Tnfrsf1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000030336Tumor necrosis factor receptor superfamily member 1B; Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1 [...]
Tnfrsf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030339Tumor necrosis factor receptor superfamily member 8; Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene e [...]
Scp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030340Non-specific lipid-transfer protein; Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.
Cpt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030345Carnitine O-palmitoyltransferase 2, mitochondrial; Belongs to the carnitine/choline acetyltransferase family.
Magoh protein networkhttps://string-db.org/network/10090.ENSMUSP00000030348Protein mago nashi homolog; Required for pre-mRNA splicing as component of the spliceosome. Plays a redundant role with MAGOHB as core component of the exon junction complex (EJC) and in the nons [...]
Lrrc42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030360Leucine-rich repeat-containing protein 42; Belongs to the LRRC42 family.
Tmem59 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030361Transmembrane protein 59; Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, lea [...]
Mrpl37 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003036539S ribosomal protein L37, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL37 family.
Ssbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030367Single-stranded DNA-binding protein 3; May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter r [...]
Col9a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030372Collagen alpha-2(IX) chain; Structural component of hyaline cartilage and vitreous of the eye.
Exo5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030375Exonuclease V; Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (IC [...]
Kcnq4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030376Potassium voltage-gated channel subfamily KQT member 4; Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of [...]
Ctps protein networkhttps://string-db.org/network/10090.ENSMUSP00000030381CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or [...]
Edn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030384Endothelin-2; Vasoconstrictor; Belongs to the endothelin/sarafotoxin family.
Ppcs protein networkhttps://string-db.org/network/10090.ENSMUSP00000030385Phosphopantothenate--cysteine ligase; Catalyzes the second step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothe [...]
Slc2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030398Solute carrier family 2, facilitated glucose transporter member 1; Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate spec [...]
Rragc protein networkhttps://string-db.org/network/10090.ENSMUSP00000030399Ras-related GTP-binding protein C; Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its sub [...]
Mycbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000030400c-Myc-binding protein; May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC (By similarity). Belongs to the AMY1 family.
Ppie protein networkhttps://string-db.org/network/10090.ENSMUSP00000030404Peptidyl-prolyl cis-trans isomerase E; Involved in pre-mRNA splicing as component of the spliceosome. Combines RNA-binding and PPIase activities. Binds mRNA and has a preference for single-strand [...]
Mycl protein networkhttps://string-db.org/network/10090.ENSMUSP00000030407Protein L-Myc.
Mfsd2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000030408Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Speci [...]
Ppt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030412Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl c [...]
Epha8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030420Ephrin type-A receptor 8; Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling [...]
Eloa protein networkhttps://string-db.org/network/10090.ENSMUSP00000030427Elongin-A; SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A [...]
Hmgcl protein networkhttps://string-db.org/network/10090.ENSMUSP00000030432Hydroxymethylglutaryl-CoA lyase, mitochondrial; Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3- methylglutaryl-CoA into ace [...]
Fuca1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030434Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoprote [...]
Pnrc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030436Proline-rich nuclear receptor coactivator 2; Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery (By similarity). May act [...]
Rnf220 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030439E3 ubiquitin-protein ligase Rnf220; E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. Independently of its E3 ligase activity, acts as a CTNNB1 st [...]
Ptch2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030443Protein patched homolog 2; Plays a role in the control of cellular growth (By similarity). May have a role in epidermal development. May act as a receptor for Sonic hedgehog (SHH); Belongs to the [...]
Urod protein networkhttps://string-db.org/network/10090.ENSMUSP00000030446Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
Toe1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030451Target of EGR1 protein 1; Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the matura [...]
Mmachc protein networkhttps://string-db.org/network/10090.ENSMUSP00000030453Methylmalonic aciduria and homocystinuria type C protein homolog; Catalyzes the reductive dealkylation of cyanocobalamin to cob(II)alamin, using FAD or FMN as cofactor and NADPH as cosubstrate. C [...]
Akr1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030455Aldo-keto reductase family 1 member A1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity tow [...]
Nasp protein networkhttps://string-db.org/network/10090.ENSMUSP00000030456Nuclear autoantigenic sperm protein; Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and linker H1 histones and stimulat [...]
Gpbp1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030460Vasculin-like protein 1; Possible transcription factor; Belongs to the vasculin family.
Pik3r3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030464Phosphatidylinositol 3-kinase regulatory subunit gamma; Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin sti [...]
Tspan1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030465Tetraspanin-1.
Lurap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030469Leucine rich adaptor protein 1; Acts as an activator of the canonical NF-kappa-B pathway and drive the production of proinflammatory cytokines. Promotes the antigen (Ag)-presenting and priming fu [...]
Lrrc41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030471Leucine-rich repeat-containing protein 41; Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination an [...]
Nsun4 protein networkhttps://string-db.org/network/10090.ENSMUSP000000304755-methylcytosine rRNA methyltransferase NSUN4; Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subun [...]
Mob3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000030477MOB kinase activator 3C; May regulate the activity of kinases.
Cyp4a31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030486Cytochrome P450, family 4, subfamily a, polypeptide 31; Belongs to the cytochrome P450 family.
Cyp4a14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030487Cytochrome P450 4A14; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing th [...]
Tal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030489T-cell acute lymphocytic leukemia protein 1 homolog; Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regu [...]
Stil protein networkhttps://string-db.org/network/10090.ENSMUSP00000030490SCL-interrupting locus protein homolog; Immediate-early gene. Plays an important role in embryonic development as well as in cellular growth and proliferation; its long- term silencing affects ce [...]
Cmpk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030491UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference [...]
Ebna1bp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030501Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.
Pax7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030508Paired box protein Pax-7; Transcription factor playing a role in myogenesis through regulation of muscle precursor cells proliferation. Belongs to the paired homeobox family.
Tas1r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030510Taste receptor type 1 member 2; Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners.
Capzb protein networkhttps://string-db.org/network/10090.ENSMUSP00000030518F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subuni [...]
Pla2g2f protein networkhttps://string-db.org/network/10090.ENSMUSP00000030526Group IIF secretory phospholipase A2; May play a role in lipid mediator production in inflammatory conditions, by providing arachidonic acid to downstream cyclooxygenases and lipoxygenases. Phosp [...]
Pla2g2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000030528Group IID secretory phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. L-alpha-1-palmitoyl-2-linoleoyl phosphatidylethanolamine is mo [...]
Pla2g2e protein networkhttps://string-db.org/network/10090.ENSMUSP00000030531Group IIE secretory phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Vwa5b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030533Von Willebrand factor A domain-containing protein 5B1.
Cda protein networkhttps://string-db.org/network/10090.ENSMUSP00000030535Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
Pink1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030536Serine/threonine-protein kinase PINK1, mitochondrial; Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of dam [...]
Ddost protein networkhttps://string-db.org/network/10090.ENSMUSP00000030538Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc [...]
Kif17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030539Kinesin-like protein KIF17; Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor 2B along microtubules.
Alpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000030551Alkaline phosphatase, tissue-nonspecific isozyme; This isozyme plays a key role in skeletal mineralization by regulating levels of diphosphate (PPi).
Ptpn12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030556Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. Dephosphorylates cellular tyrosine kinases, such as ERB [...]
Gnat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030561Guanine nucleotide-binding protein G(t) subunit alpha-3; Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in [...]
Sema3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000030568Semaphorin-3C; Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functi [...]
Ptp4a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030578Protein tyrosine phosphatase type IVA 2; Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Inhibits geranylgeranyl transferase type II activity by blo [...]
Azin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030581Antizyme inhibitor 2; Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that cou [...]
Ak2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030583Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nuc [...]
A3galt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030585Alpha-1,3-galactosyltransferase 2; Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of [...]
Ccdc28b protein networkhttps://string-db.org/network/10090.ENSMUSP00000030586Coiled-coil domain-containing protein 28B; Involved in ciliogenesis. Regulates cilia length through its interaction with MAPKAP1/SIN1 but independently of mTORC2 complex. Modulates mTORC2 complex [...]
Phc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030588Polyhomeotic-like protein 2; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, includi [...]
Rcan3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030606Calcipressin-3; Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By simil [...]
Zbtb8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000030610Zinc finger and BTB domain-containing protein 8A; May be involved in transcriptional regulation.
CK137956 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030614cDNA sequence CK137956.
Syf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030622Pre-mRNA-splicing factor SYF2; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the SYF2 family.
Sfpq protein networkhttps://string-db.org/network/10090.ENSMUSP00000030623Splicing factor, proline- and glutamine-rich; DNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and f [...]
Tmem50a protein networkhttps://string-db.org/network/10090.ENSMUSP00000030626Transmembrane protein 50A.
Rhd protein networkhttps://string-db.org/network/10090.ENSMUSP00000030627Blood group Rh(D) polypeptide; May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
Maco1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030628Macoilin; Plays a role in the regulation of neuronal activity. Belongs to the macoilin family.
Stmn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030636Stathmin; Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 m [...]
Ncdn protein networkhttps://string-db.org/network/10090.ENSMUSP00000030637Neurochondrin; Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial [...]
Psmb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030642Proteasome subunit beta type-2; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles wi [...]
Extl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030643Exostosin-like 1; Probable glycosyltransferase; Belongs to the glycosyltransferase 47 family.
Zfp593 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030644Zinc finger protein 593; Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting [...]
Cnksr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030645Connector enhancer of kinase suppressor of Ras 1.
Sh3bgrl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030651SH3 domain-binding glutamic acid-rich-like protein 3; Could act as a modulator of glutaredoxin biological activity.
Trappc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030660Trafficking protein particle complex subunit 3; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily.
Gpn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030661GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-lo [...]
Gpatch3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030662G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from CXCR4 promoter and therefore it might control neural crest cell migration in [...]
Nudc protein networkhttps://string-db.org/network/10090.ENSMUSP00000030665Nuclear migration protein nudC; Plays a role in neurogenesis and neuronal migration. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis (By similarity).
Slc9a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030669Sodium/hydrogen exchanger 1; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by th [...]
Sytl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030674Synaptotagmin-like protein 1; Binds phosphatidylinositol 3,4,5-trisphosphate (By similarity). May play a role in vesicle trafficking. Acts as a RAB27A effector protein and may play a role in cyto [...]
Mrps15 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003067528S ribosomal protein S15, mitochondrial; Belongs to the universal ribosomal protein uS15 family.
Grik3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030676Glutamate receptor ionotropic, kainate 3; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transm [...]
Map3k6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030677Mitogen-activated protein kinase kinase kinase 6; Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways.
Gnl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030684Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell [...]
Rspo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030687R-spondin-1; Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 an [...]
Pclo protein networkhttps://string-db.org/network/10090.ENSMUSP00000030691Protein piccolo; Scaffold protein of the presynaptic cytomatrix at the active zone (CAZ) which is the place in the synapse where neurotransmitter is released. After synthesis, participates in the [...]
Fgr protein networkhttps://string-db.org/network/10090.ENSMUSP00000030693Tyrosine-protein kinase Fgr; Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors devoid of kinase activity and contributes to the regulation of immune response [...]
Fam76a protein networkhttps://string-db.org/network/10090.ENSMUSP00000030696Protein FAM76A.
Stx12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030698Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (i [...]
Ppp1r8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030702Nuclear inhibitor of protein phosphatase 1; Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-ass [...]
Smpdl3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000030709Acid sphingomyelinase-like phosphodiesterase 3b; Lipid-modulating phosphodiesterase. Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition [...]
Sema3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000030714Semaphorin-3A; Plays a role in growth cones guidance. May function to pattern sensory projections by selectively repelling axons that normally terminate dorsally. Involved in the development of t [...]
Mtf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030723Metal regulatory transcription factor 1; Activates the metallothionein I promoter. Binds to the metal responsive element (MRE).
Sesn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030724Sestrin-2; Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 a [...]
Rcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030726Regulator of chromosome condensation; Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nucl [...]
Trnau1ap protein networkhttps://string-db.org/network/10090.ENSMUSP00000030730tRNA selenocysteine 1-associated protein 1; Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of [...]
Taf12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030731Transcription initiation factor TFIID subunit 12; TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs compo [...]
Sf3a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030734Splicing factor 3A subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of [...]
Utp11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030738Probable U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.
Epb41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030739Protein 4.1; Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformabili [...]
Ptpru protein networkhttps://string-db.org/network/10090.ENSMUSP00000030741Receptor-type tyrosine-protein phosphatase U; Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proli [...]
Mecr protein networkhttps://string-db.org/network/10090.ENSMUSP00000030742Enoyl-[acyl-carrier-protein] reductase, mitochondrial; Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fa [...]
Casp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030747Caspase-9 subunit p10; Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves an [...]
Fbxo42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030757F-box only protein 42; Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and d [...]
Necap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030760Adaptin ear-binding coat-associated protein 2; Involved in endocytosis.
Cdk14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030763Cyclin-dependent kinase 14; Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regula [...]
Padi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030765Protein-arginine deiminase type-2; Catalyzes the deimination of arginine residues of proteins.
Psmc2 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003076926S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in [...]
Dnajc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030771DnaJ homolog subfamily C member 2; Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-as [...]
Xrcc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030773DNA repair protein XRCC2; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of [...]
Chd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030775Chromodomain-helicase-DNA-binding protein 5; Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated 'Lys- [...]
Galntl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030778Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5; Probable inactive glycosyltransferase required during spermatid development. May participate in protein loading into the acr [...]
Hes2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030782Transcription factor HES-2; Transcriptional repressor of genes that require a bHLH protein for their transcription.
Prkag2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000307845'-AMP-activated protein kinase subunit gamma-2; AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energ [...]
Espn protein networkhttps://string-db.org/network/10090.ENSMUSP00000030785Espin; Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimension, dynamics and signaling capacities of the actin filament-rich microvilli in the mechano [...]
Rheb protein networkhttps://string-db.org/network/10090.ENSMUSP00000030787GTP-binding protein Rheb; Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through act [...]
Smarcd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030791SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alter [...]
Tas1r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030792Taste receptor type 1 member 1; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, [...]
Abcf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030795ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
Vamp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030797Vesicle-associated membrane protein 3; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the synaptobrevin family.
Fastk protein networkhttps://string-db.org/network/10090.ENSMUSP00000030800Fas-activated serine/threonine kinase; Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro- apoptotic form of the rece [...]
Uts2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030803Urotensin-2; Highly potent vasoconstrictor.
Errfi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030811ERBB receptor feedback inhibitor 1; Negative regulator of EGFR signaling in skin morphogenesis. Acts as a negative regulator for several EGFR family members, including ERBB2, ERBB3 and ERBB4. Inh [...]
Cenps protein networkhttps://string-db.org/network/10090.ENSMUSP00000030813Centromere protein S; DNA-binding component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 comple [...]
Cdk5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030814Cyclin-dependent-like kinase 5; Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuron [...]
Cort protein networkhttps://string-db.org/network/10090.ENSMUSP00000030815Cortistatin-14.
Dffa protein networkhttps://string-db.org/network/10090.ENSMUSP00000030816DNA fragmentation factor subunit alpha; Inhibitor of the caspase-activated DNase (DFF40).
Car6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030817Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown.
Slc2a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030826Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucos [...]
H6pd protein networkhttps://string-db.org/network/10090.ENSMUSP00000030830GDH/6PGL endoplasmic bifunctional protein; Bifunctional enzyme localized in the lumen of the endoplasmic reticulum that catalyzes the first two steps of the oxidative branch of the pentose phosph [...]
Nos3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030834Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular e [...]
Ctnnbip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030839Beta-catenin-interacting protein 1; Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway; Belongs to the CTNNBIP1 family.
Angptl7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030840Angiopoietin-related protein 7; Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the [...]
Klhl7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030841Kelch-like protein 7; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substr [...]
Lzic protein networkhttps://string-db.org/network/10090.ENSMUSP00000030842Protein LZIC.
Rbp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030848Retinoid-binding protein 7; Intracellular transport of retinol; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Fam126a protein networkhttps://string-db.org/network/10090.ENSMUSP00000030849Hyccin; Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) s [...]
Tomm7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030851Mitochondrial import receptor subunit TOM7 homolog; Required for assembly and stability of the TOM complex (By similarity). Positive regulator of PRKN translocation to damaged mitochondria. Acts [...]
Rint1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030852RAD50-interacting protein 1; Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum; the function is proposed to depend on its association in the NRZ complex w [...]
Mad2l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030860Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the er [...]
Draxin protein networkhttps://string-db.org/network/10090.ENSMUSP00000030862Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during developm [...]
Agtrap protein networkhttps://string-db.org/network/10090.ENSMUSP00000030865Type-1 angiotensin II receptor-associated protein; Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechan [...]
Sema3d protein networkhttps://string-db.org/network/10090.ENSMUSP00000030868Semaphorin-3D; Induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin (By similarity).
Orc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030872Origin recognition complex subunit 5; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define ori [...]
Slc26a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030878Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ. Prestin is a bidirectional voltage-to- [...]
Clcn6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030879Chloride transport protein 6; Chloride transport protein, initially identified as voltage- gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functio [...]
Pmpcb protein networkhttps://string-db.org/network/10090.ENSMUSP00000030882Mitochondrial-processing peptidase subunit beta; Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors [...]
Mfn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030884Mitofusin-2; Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibri [...]
Miip protein networkhttps://string-db.org/network/10090.ENSMUSP00000030886Migration and invasion-inhibitory protein; Inhibits glioma cells invasion and down-regulates adhesion- and motility-associated genes such as NFKB2 and ICAM1. Exhibits opposing effects to IGFBP2 o [...]
Dffb protein networkhttps://string-db.org/network/10090.ENSMUSP00000030893DNA fragmentation factor subunit beta; Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.
Lrrc47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030894Leucine-rich repeat-containing protein 47.
Wrap73 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030895WD repeat-containing protein WRAP73; The SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP [...]
Tprgl protein networkhttps://string-db.org/network/10090.ENSMUSP00000030896Tumor protein p63-regulated gene 1-like protein; Presynaptic protein involved in the synaptic transmission tuning. Regulates synaptic release probability by decreasing the calcium sensitivity of [...]
Megf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030897Multiple epidermal growth factor-like domains protein 6.
Arhgef16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030898Rho guanine nucleotide exchange factor 16; Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migrat [...]
Ints11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030901Integrator complex subunit 11; Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing [...]
Prdm16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030902Histone-lysine N-methyltransferase PRDM16; Binds DNA and functions as a transcriptional regulator. Displays histone methyltransferase activity and monomethylates 'Lys-9' of histone H3 (H3K9me1) i [...]
Atad3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000030903ATPase family AAA domain-containing protein 3; Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important rol [...]
Ssu72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030905RNA polymerase II subunit A C-terminal domain phosphatase SSU72; Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA proces [...]
Rer1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030914Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment; Belongs to the RER1 family.
Morn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030915MORN repeat-containing 1.
Ski protein networkhttps://string-db.org/network/10090.ENSMUSP00000030917Ski oncogene; May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling; B [...]
Prkcz protein networkhttps://string-db.org/network/10090.ENSMUSP00000030922Protein kinase C zeta type; Calcium- and diacylglycerol-independent serine/threonine- protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein ( [...]
Gabrd protein networkhttps://string-db.org/network/10090.ENSMUSP00000030925Gamma-aminobutyric acid receptor subunit delta; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor an [...]
Prxl2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000030935Prostamide/prostaglandin F synthase; Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostagla [...]
Mmp23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030937Matrix metalloproteinase-23, soluble form; Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity); Belongs to the [...]
Mrpl20 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003094239S ribosomal protein L20, mitochondrial; Belongs to the bacterial ribosomal protein bL20 family.
Ccnl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030944Cyclin-L2; Involved in pre-mRNA splicing. May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors.
Mxra8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030947Matrix remodeling-associated protein 8; Transmembrane protein which can modulate activity of various signaling pathways, probably via binding to integrin ITGAV:ITGB3. Mediates heterophilic cell-c [...]
Dvl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030948Segment polarity protein dishevelled homolog DVL-1; Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream [...]
Tas1r3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030949Taste receptor type 1 member 3; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, [...]
Cptp protein networkhttps://string-db.org/network/10090.ENSMUSP00000030950Ceramide-1-phosphate transfer protein; Mediates the intracellular transfer of ceramide-1-phosphate (C1P) between organelle membranes and the cell membrane. Required for normal structure of the Go [...]
Tnfrsf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030952Tumor necrosis factor receptor superfamily member 4; Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity (By similarity).
Cd38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030964ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-ind [...]
Adgra3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030971Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway.
Trmt44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030980Probable tRNA (uracil-O(2)-)-methyltransferase; Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
Rgs12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030984Regulator of G-protein signaling 12; Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby d [...]
Hgfac protein networkhttps://string-db.org/network/10090.ENSMUSP00000030985Hepatocyte growth factor activator short chain; Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.
Lrpap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000030986Alpha-2-macroglobulin receptor-associated protein; Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.
Nelfa protein networkhttps://string-db.org/network/10090.ENSMUSP00000030993Negative elongation factor A; Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (By similarity). The NELF complex, [...]
Man2b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031002Epididymis-specific alpha-mannosidase; Plays an important role in the early step of spermatogenesis; Belongs to the glycosyl hydrolase 38 family.
Ppp2r2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000031003Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the [...]
Evc protein networkhttps://string-db.org/network/10090.ENSMUSP00000031005Ellis-van Creveld syndrome protein homolog; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Involved in endochondral growth and skeletal development.
Nsg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031009Neuronal vesicle trafficking-associated protein 1; Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosome [...]
Rab28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031011Ras-related protein Rab-28.
Fosl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031017Fos-related antigen 2; Controls osteoclast survival and size. As a dimer with JUN, activates LIF transcription. Activates CEBPB transcription in PGE2- activated osteoblasts (By similarity).
Rbks protein networkhttps://string-db.org/network/10090.ENSMUSP00000031018Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histi [...]
4930548H24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000031020RIKEN cDNA 4930548H24 gene.
Mrpl33 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003102439S ribosomal protein L33, mitochondrial; Belongs to the bacterial ribosomal protein bL33 family.
Snx17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031029Sorting nexin-17; Critical regulator of endosomal recycling of numerous surface proteins, including integrins, signaling receptor and channels. Binds to NPxY sequences in the cytoplasmic tails of [...]
Ppm1g protein networkhttps://string-db.org/network/10090.ENSMUSP00000031032Protein phosphatase 1G; May be involved in regulation of cell cycle. Belongs to the PP2C family.
Slc30a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031037Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles.
Ociad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031038OCIA domain-containing protein 1; Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes [...]
Cwh43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031040PGAP2-interacting protein; Involved in lipid remodeling during GPI-anchor maturation. Belongs to the PGAP2IP family.
Yipf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031045Protein YIPF7; Belongs to the YIP1 family.
Cgref1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031051Cell growth regulator with EF hand domain protein 1; Mediates cell-cell adhesion in a calcium-dependent manner. Able to inhibit growth in several cell lines (By similarity).
Khk protein networkhttps://string-db.org/network/10090.ENSMUSP00000031053Ketohexokinase; Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.
Emilin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031055EMILIN-1; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vesse [...]
Mapre3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031058Microtubule-associated protein RP/EB family member 3; Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promo [...]
Dhx15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031061Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to [...]
Sepsecs protein networkhttps://string-db.org/network/10090.ENSMUSP00000031069O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. Belongs to the SepSecS family.
Anapc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031072Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G [...]
Zcchc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031077rRNA N6-adenosine-methyltransferase ZCCHC4; rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA. N6-methylation of adenine(4220) in 28S rRNA is require [...]
1700001C02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000031078Protein FAM166C.
Fam114a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031080Protein Noxp20; May play a role in neuronal cell development; Belongs to the FAM114 family.
Pi4k2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000031081Phosphatidylinositol 4-kinase type 2-beta; Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be [...]
Sel1l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031090Protein sel-1 homolog 3.
D5Ertd579e protein networkhttps://string-db.org/network/10090.ENSMUSP00000031091Uncharacterized protein KIAA0232.
Cckar protein networkhttps://string-db.org/network/10090.ENSMUSP00000031093Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher a [...]
Klb protein networkhttps://string-db.org/network/10090.ENSMUSP00000031096Beta-klotho; Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increa [...]
Tada2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000031097Transcriptional adapter.
Grpel1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031099GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mit [...]
Ugdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000031103UDP-glucose 6-dehydrogenase; Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulf [...]
Rhoh protein networkhttps://string-db.org/network/10090.ENSMUSP00000031106Rho-related GTP-binding protein RhoH; Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. Inhibits the activation of NF-kappa-B by TNF and I [...]
Chrna9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031108Cholinergic receptor, nicotinic, alpha polypeptide 9.
Nsun7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031109Putative methyltransferase NSUN7; May have S-adenosyl-L-methionine-dependent methyl-transferase activity.
Gnpda2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031117Glucosamine-6-phosphate isomerase 2; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
Gabrg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031119Gamma-aminobutyric acid receptor subunit gamma-1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor [...]
Gabra4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031121Gamma-aminobutyric acid receptor subunit alpha-4; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor [...]
Gabrb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031122Gamma-aminobutyric acid receptor subunit beta-1; Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine re [...]
Slc10a4l protein networkhttps://string-db.org/network/10090.ENSMUSP00000031124Solute carrier family 10 (sodium/bile acid cotransporter family), member 4-like.
Slc10a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031127Sodium/bile acid cotransporter 4; Transporter for bile acids; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
Uchl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031131Ubiquitin carboxyl-terminal hydrolase isozyme L1; Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins (Probable). This enzyme is a th [...]
Srd5a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031143Polyprenol reductase; Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis [...]
Tmem165 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031144Transmembrane protein 165; May function as a calcium/proton transporter involved in calcium and in lysosomal pH homeostasis. Therefore, it may play an indirect role in protein glycosylation (By s [...]
Pdcl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031145Phosducin-like protein 2; May play a role in germ cell maturation.
Nmu protein networkhttps://string-db.org/network/10090.ENSMUSP00000031146Neuromedin precursor-related peptide 33; [Neuromedin-U-23]: Ligand for receptors NMUR1 and NMUR2 (By similarity). Stimulates muscle contractions of specific regions of the gastrointestinal tract. [...]
Paics protein networkhttps://string-db.org/network/10090.ENSMUSP00000031160Phosphoribosylaminoimidazole-succinocarboxamide synthase; In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
Thegl protein networkhttps://string-db.org/network/10090.ENSMUSP00000031161Testicular haploid expressed gene protein-like.
Polr2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000031167DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest com [...]
Cenpc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031170Centromere protein C; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segre [...]
Gnrhr protein networkhttps://string-db.org/network/10090.ENSMUSP00000031172Gonadotropin-releasing hormone receptor; Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing ho [...]
Tmprss11d protein networkhttps://string-db.org/network/10090.ENSMUSP00000031175Transmembrane protease serine 11D non-catalytic chain; May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in [...]
Ugt2b34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031181UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
Ugt2b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031183UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
Ugt2b35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031186UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
Dr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031190Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the f [...]
Ugt2a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031195UDP-glucuronosyltransferase 2A3; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water so [...]
Dipk1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000031198Divergent protein kinase domain 1A.
Sult1e1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031201Sulfotransferase 1E1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone (By similarity). Is a ke [...]
Smr3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000031211Submaxillary gland androgen-regulated protein 3A; May play a role in protection or detoxification.
Brdt protein networkhttps://string-db.org/network/10090.ENSMUSP00000031215Bromodomain testis-specific protein; Testis-specific chromatin protein that specifically binds histone H4 acetylated at 'Lys-5' and 'Lys-8' (H4K5ac and H4K8ac, respectively) and plays a key role [...]
Enam protein networkhttps://string-db.org/network/10090.ENSMUSP00000031222Enamelin; Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation.
Tgfbr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031224Transforming growth factor beta receptor type 3; Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors (By similarity).
Zfp326 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031227DBIRD complex subunit ZNF326; Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates tran [...]
Gbp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031235Guanylate-binding protein 8.
Gbp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031238Guanylate-binding protein 9.
Abcg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031239ATP-binding cassette sub-family G member 3.
Ibsp protein networkhttps://string-db.org/network/10090.ENSMUSP00000031246Bone sialoprotein 2; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cel [...]
Sparcl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031249SPARC-like protein 1; Belongs to the SPARC family.
Nudt9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031250ADP-ribose pyrophosphatase, mitochondrial; Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'-phosphate; Belongs to the Nudix hydrolase family. NudF subfamily.
Hsd17b11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031251Estradiol 17-beta-dehydrogenase 11; Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidoge [...]
Klhl8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031254Kelch-like protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation [...]
Aff1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031256AF4/FMR2 family member 1; Belongs to the AF4 family.
Coq2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000312624-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction [...]
Slc10a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031263Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner.
Cds1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031273Phosphatidate cytidylyltransferase 1; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression [...]
Rasgef1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000031276Ras-GEF domain-containing family member 1B; Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro).
Fgf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031280Fibroblast growth factor 5; Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhi [...]
Antxr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031281Anthrax toxin receptor 2; Necessary for cellular interactions with laminin and the extracellular matrix; Belongs to the ATR family.
Crybb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031286Beta-crystallin B1B; Crystallins are the dominant structural components of the vertebrate eye lens.
Tpst2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031287Protein-tyrosine sulfotransferase 2; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
Tfip11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031288Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in tw [...]
Srrd protein networkhttps://string-db.org/network/10090.ENSMUSP00000031289SRR1-like protein; Plays a role in the regulation of heme biosynthesis and in the regulation of the expression of core clock genes. Belongs to the SRR1 family.
Asphd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031291Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase.
Tesc protein networkhttps://string-db.org/network/10090.ENSMUSP00000031304Calcineurin B homologous protein 3; Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, c [...]
Wsb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031309WD repeat and SOCS box-containing protein 2; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitina [...]
Dck protein networkhttps://string-db.org/network/10090.ENSMUSP00000031311Deoxycytidine kinase; Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA).
Alb protein networkhttps://string-db.org/network/10090.ENSMUSP00000031314Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulati [...]
Rassf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031317Ras association domain-containing protein 6; Involved in the induction of apoptosis. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF- kappa-B.
Cxcl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031318C-X-C motif chemokine 5; May participate in the recruitment of inflammatory cells by injured or infected tissue. GCP-2(1-78) and, more potent, GCP-2(9-78) attract neutrophils and are involved in [...]
Ppbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000031319Chemokine subfamily B Cys-X-Cys.
Pf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031320Platelet factor 4; Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the [...]
Cxcl15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031322C-X-C motif chemokine 15; Chemotactic for neutrophils. Involved in lung-specific neutrophil trafficking during normal and inflammatory conditions.
Ereg protein networkhttps://string-db.org/network/10090.ENSMUSP00000031324Proepiregulin; Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (By similarity). Contributes to inflammation, wound healing, tissue repair, and oocyte [...]
Areg protein networkhttps://string-db.org/network/10090.ENSMUSP00000031325Amphiregulin; Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts; Belongs to the a [...]
Cxcl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031326C-X-C motif chemokine 3; Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.
Cxcl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031327Growth-regulated alpha protein; Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation (By similarity). Hematoregulatory chemokine, which, in vitro, su [...]
Ccng2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031331Cyclin-G2; May play a role in growth regulation and in negative regulation of cell cycle progression.
Gtf2h3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031333General transcription factor IIH subunit 3; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotid [...]
Eif2b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031334Translation initiation factor eIF-2B subunit alpha; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family.
Cdk2ap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031341Cyclin-dependent kinase 2-associated protein 1; specific inhibitor of the cell-cycle kinase CDK2.
Rchy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031345RING finger and CHY zinc finger domain-containing protein 1; Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Prefer [...]
Rilpl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031347RILP-like protein 2; Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines (By similarity). Plays a role in cellular prote [...]
Arl6ip4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031351ADP-ribosylation factor-like protein 6-interacting protein 4; Involved in modulating alternative pre-mRNA splicing with either 5' distal site activation or preferential use of 3' proximal site; B [...]
Abcb9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031354ATP-binding cassette sub-family B member 9; ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broa [...]
Uso1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031355General vesicular transport factor p115; General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent bind [...]
Sdad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031364Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm.
Kntc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031366Kinetochore-associated protein 1; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-M [...]
Slc15a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031367Solute carrier family 15 member 4; Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides (By similarity); Belongs to the PTR2/POT transporter (TC 2.A.17) fa [...]
Scarb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031377Lysosome membrane protein 2; Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting; Belongs to the CD36 family.
Stx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031378Syntaxin-2; Essential for epithelial morphogenesis. May mediate Ca(2+)- regulation of exocytosis acrosomal reaction in sperm.
B3gnt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031384N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4; Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Has activity for type 2 oligosacc [...]
Vps33a protein networkhttps://string-db.org/network/10090.ENSMUSP00000031388Vacuolar protein sorting-associated protein 33A; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. [...]
Il31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031389Interleukin-31; Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. May function in skin immunity. Enhances myeloid progenitor cell s [...]
Mmp17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031390Matrix metalloproteinase-17; Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth f [...]
Bcl7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000031391B-cell CLL/lymphoma 7 protein family member A; Belongs to the BCL7 family.
Hpd protein networkhttps://string-db.org/network/10090.ENSMUSP000000313984-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine; Belongs to the 4HPPD family.
Psph protein networkhttps://string-db.org/network/10090.ENSMUSP00000031399Phosphoserine phosphatase; Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates (By sim [...]
Mapkapk5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031410MAP kinase-activated protein kinase 5; Tumor suppressor serine/threonine-protein kinase involved in mTORC1 signaling and post-transcriptional regulation. Phosphorylates FOXO3, ERK3/MAPK6, ERK4/MA [...]
Aldh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031411Aldehyde dehydrogenase, mitochondrial; Is capable of converting retinaldehyde to retinoic acid.
Acad10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031412Acyl-CoA dehydrogenase family member 10; Acyl-CoA dehydrogenase only active with R- and S-2-methyl- C15-CoA.
Brap protein networkhttps://string-db.org/network/10090.ENSMUSP00000031414BRCA1-associated protein; Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras respo [...]
Fam216a protein networkhttps://string-db.org/network/10090.ENSMUSP00000031419Protein FAM216A; Belongs to the FAM216 family.
Gpn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031420GPN-loop GTPase 3; Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
Atp2a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031423Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic [...]
Ift81 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031426Intraflagellar transport protein 81 homolog; Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of [...]
P2rx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031429P2X purinoceptor 4; Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin (By similarity).
Rnf34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031434E3 ubiquitin-protein ligase RNF34; E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiqu [...]
Morn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031437MORN repeat-containing protein 3.
Aacs protein networkhttps://string-db.org/network/10090.ENSMUSP00000031445Acetoacetyl-CoA synthetase; Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development (By similarity).
Tmem132b protein networkhttps://string-db.org/network/10090.ENSMUSP00000031446Transmembrane protein 132B.
Anxa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031447Annexin A3; Inhibitor of phospholipase A2, also possesses anti-coagulant properties; Belongs to the annexin family.
Mfsd7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000031455Solute carrier family 49 member A3.
Pde6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000031456Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta; This protein participates in processes of transmission and amplification of the visual signal. Necessary for the formation of a func [...]
Pxmp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031472Peroxisomal membrane protein 2; Seems to be involved in pore-forming activity and may contribute to the unspecific permeability of the peroxisomal membrane.
Golga3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031477Golgin subfamily A member 3; Plays an important role in spermatogenesis and/or testis development. Probably identical with the serologically detectable male antigen (SDM). Probably involved in ma [...]
Ddx51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031478ATP-dependent RNA helicase DDX51; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits; Belongs to the DEAD box helicase family. DDX51/DBP6 subfamily.
Prkab1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000314865'-AMP-activated protein kinase subunit beta-1; Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy m [...]
Rab35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031492Ras-related protein Rab-35; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle bet [...]
Pla2g1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000031495Phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precurso [...]
Triap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031508TP53-regulated inhibitor of apoptosis 1; Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, t [...]
Srsf9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031513Serine/arginine-rich splicing factor 9; Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10 (By similarity [...]
Cyp2w1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031521Cytochrome P450 2W1; Seems to have broad catalytic activity towards several chemicals, including polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines. Active also in the metabolism of [...]
Acads protein networkhttps://string-db.org/network/10090.ENSMUSP00000031524Short-chain specific acyl-CoA dehydrogenase, mitochondrial; Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty a [...]
Sppl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031530Signal peptide peptidase-like 3; Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane protein substrates in or close to their luminal transmembrane domain boundaries. A [...]
Psmg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031531Proteasome assembly chaperone 3; Chaperone protein which promotes assembly of the 20S proteasome. May cooperate with PSMG1-PSMG2 heterodimers to orchestrate the correct assembly of proteasomes; B [...]
Tfec protein networkhttps://string-db.org/network/10090.ENSMUSP00000031533Transcription factor EC; Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant aci [...]
Mad1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031534Mitotic spindle assembly checkpoint protein MAD1; Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plat [...]
Hnf1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000031535Hepatocyte nuclear factor 1-alpha; Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Binds to the inver [...]
Mrm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031536rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mi [...]
2210016L21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000031538Protein CUSTOS; Plays a role in the regulation of Wnt signaling pathway during early development; Belongs to the CUSTOS family.
Snx8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031539Sorting nexin-8; May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network (By similarity) [...]
Oasl2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000315422'-5'-oligoadenylate synthase-like protein 2; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. Synthesizes oligomers of 2'-5 [...]
4930519G04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000031547RIKEN cDNA 4930519G04 gene.
Gm4951 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031549Interferon-gamma-inducible GTPase Ifgga2 protein.
Tmem168 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031554Transmembrane protein 168.
Lfng protein networkhttps://string-db.org/network/10090.ENSMUSP00000031555Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of [...]
Tmem106b protein networkhttps://string-db.org/network/10090.ENSMUSP00000031556Transmembrane protein 106B; Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lys [...]
Mmab protein networkhttps://string-db.org/network/10090.ENSMUSP00000031560Corrinoid adenosyltransferase; Adenosyltransferase involved in intracellular vitamin B12 metabolism. Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer t [...]
Fscn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031565Fascin; Actin-binding protein that contains 2 major actin binding sites (By similarity). Organizes filamentous actin into parallel bundles. Plays a role in the organization of actin filament bund [...]
Spdye4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000031574Speedy/RINGO cell cycle regulator family, member E4B.
Ung protein networkhttps://string-db.org/network/10090.ENSMUSP00000031587Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
Usp30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031588Ubiquitin carboxyl-terminal hydrolase 30; Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRK [...]
Rbm19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031590Probable RNA-binding protein 19; Plays a role in embryo pre-implantation development. Belongs to the RRM MRD1 family.
Lhx5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031591LIM/homeobox protein Lhx5; Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.
Sdsl protein networkhttps://string-db.org/network/10090.ENSMUSP00000031594Serine dehydratase-like; Has low serine dehydratase and threonine dehydratase activity; Belongs to the serine/threonine dehydratase family.
Plbd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031597Putative phospholipase B-like 2 15 kDa form; Putative phospholipase.
Ddx54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031598ATP-dependent RNA helicase DDX54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors (By similarity). Belongs to the DEAD box helicase family. DDX54/DB [...]
Dtx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031607E3 ubiquitin-protein ligase DTX1; Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts a [...]
Aimp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031613Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1 [...]
Rpl6 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003161760S ribosomal protein L6; Component of the large ribosomal subunit.
Ccz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031621Vacuolar fusion protein CCZ1 homolog; Acts in concert with MON1A, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form i [...]
Ocm protein networkhttps://string-db.org/network/10090.ENSMUSP00000031622Oncomodulin; Has some calmodulin-like activity with respect to enzyme activation and growth regulation. Binds two calcium ions; Belongs to the parvalbumin family.
1700018F24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000031624RIKEN cDNA 1700018F24 gene.
Arpc1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000031625Actin-related protein 2/3 complex subunit 1A; Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleat [...]
Pdap1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003162728 kDa heat- and acid-stable phosphoprotein.
Ptcd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031628Pentatricopeptide repeat-containing protein 1, mitochondrial; Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria- encod [...]
Zkscan14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031632Zinc finger protein 394; May be involved in transcriptional regulation.
Cyp3a16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031633Cytochrome P450 3A16; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a va [...]
Cdk8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031640Cyclin-dependent kinase 8; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridg [...]
Rasl11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000031646Ras-like protein family member 11A; Regulator of rDNA transcription. Acts in cooperation UBF/UBTF and positively regulates RNA polymerase I transcription. Belongs to the small GTPase superfamily. [...]
Cdx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031650Homeobox protein CDX-2; Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to ma [...]
Pan3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031651PAN2-PAN3 deadenylation complex subunit Pan3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediat [...]
Flt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031653Vascular endothelial growth factor receptor 1; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic v [...]
Pomp protein networkhttps://string-db.org/network/10090.ENSMUSP00000031654Proteasome maturation protein; Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded after completion of proteasome maturation (By similarity). Me [...]
Slc46a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031655Solute carrier family 46 member 3.
C8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000031663Complement component C8 beta chain; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of ta [...]
Col1a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031668Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family.
Gng11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031670Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling s [...]
Gngt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031673Guanine nucleotide-binding protein G(T) subunit gamma-T1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. Th [...]
Tfpi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031674Tissue factor pathway inhibitor 2; May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effec [...]
Tspan12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031678Tetraspanin-12; Regulator of cell surface receptor signal transduction. Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1- MMP. Activates ADAM10-dependent cleavage activity [...]
Ing3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031680Inhibitor of growth protein 3; Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleoso [...]
Wnt16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031681Protein Wnt-16; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete r [...]
Hyal6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031690Hyaluronidase.
Hyal4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031691Hyaluronidase-4; Endo-hyaluronidase that degrades hyaluronan to smaller oligosaccharide fragments. Has also chondroitin sulfate hydrolase activity, The best substrate being the galactosaminidic l [...]
Bcl7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000031692B-cell CLL/lymphoma 7 protein family member B; Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 [...]
Lmod2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031694Leiomodin-2; Mediates nucleation of actin filaments and thereby promotes actin polymerization (By similarity). Plays a role in the regulation of actin filament length. Required for normal sarcome [...]
Wasl protein networkhttps://string-db.org/network/10090.ENSMUSP00000031695Neural Wiskott-Aldrich syndrome protein; Regulates actin polymerization by stimulating the actin- nucleating activity of the Arp2/3 complex. Involved in various processes, such as mitosis and cyt [...]
Cul1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031697Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle pr [...]
Aass protein networkhttps://string-db.org/network/10090.ENSMUSP00000031707Alpha-aminoadipic semialdehyde synthase, mitochondrial; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine- oxoglutarat [...]
Fezf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031709Fez family zinc finger protein 1; Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of [...]
Slc13a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031713Solute carrier family 13 member 1; Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney; Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
Pax4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031718Paired box protein Pax-4; Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that competes with PAX6 in binding to a common e [...]
Fscn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031719Fascin-3; Acts as an actin bundling protein.
Gnb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031726Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling sys [...]
Gigyf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031727GRB10-interacting GYF protein 1; May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phos [...]
Pcolce protein networkhttps://string-db.org/network/10090.ENSMUSP00000031731Procollagen C-endopeptidase enhancer 1; Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity.
Fbxo24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031732F-box only protein 24; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Lrch4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031734Leucine-rich repeat and calponin homology domain-containing protein 4.
Ppp1r35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031739Protein phosphatase 1 regulatory subunit 35; Inhibits PPP1CA phosphatase activity; Belongs to the PPP1R35 family.
Mepce protein networkhttps://string-db.org/network/10090.ENSMUSP000000317407SK snRNA methylphosphate capping enzyme; S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.
Cyp3a13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031741Cytochrome P450 3A13; Can activate aflatoxin B1 to a genotoxic product.
Nobox protein networkhttps://string-db.org/network/10090.ENSMUSP00000031749Homeobox protein NOBOX; Transcription factor which plays an essential role in postnatal follicle development. Binds preferentially to the DNA sequences 5'-TAATTG-3', 5'-TAGTTG-3' and 5'-TAATTA-3' [...]
Arhgef5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031750Rho guanine nucleotide exchange factor 5; Guanine nucleotide exchange factor which activates Rho GTPases. Strongly activates RHOA. Also strongly activates RHOB, weakly activates RHOC and RHOG and [...]
Pon3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031773Serum paraoxonase/lactonase 3; Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hyd [...]
1700012A03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000031778RIKEN cDNA 1700012A03 gene.
Calu protein networkhttps://string-db.org/network/10090.ENSMUSP00000031779Calumenin; Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma- carboxylase GGCX. Binds 7 calcium ions with a low affinit [...]
Evx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031787Homeobox even-skipped homolog protein 1; May play a role in the specification of neuronal cell types. May play a role in the dorsoventral specification of mesodermal cell fate.
Hibadh protein networkhttps://string-db.org/network/10090.ENSMUSP000000317883-hydroxyisobutyrate dehydrogenase, mitochondrial; Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.
Nt5c3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031793Cytosolic 5'-nucleotidase 3A; Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP). CMP seems to be the preferred substrat [...]
Fkbp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031795Peptidyl-prolyl cis-trans isomerase FKBP9; PPIases accelerate the folding of proteins during protein synthesis.
Ssmem1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031798Serine-rich single-pass membrane protein 1.
Avl9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031805Late secretory pathway protein AVL9 homolog; Functions in cell migration; Belongs to the AVL9 family.
Cpa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031806Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.
Cep41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031810Centrosomal protein of 41 kDa; Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the b [...]
Herc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031817E3 ISG15--protein ligase Herc6; Major E3 ligase for ISG15 conjugation. Acts as a positive regulator of innate antiviral response in cells induced by interferon.
Abcg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031822Broad substrate specificity ATP-binding cassette transporter ABCG2; Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes a wide va [...]
Doxl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031837Amine oxidase.
Igf2bp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031838Insulin-like growth factor 2 mRNA-binding protein 3; RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allow [...]
Gpnmb protein networkhttps://string-db.org/network/10090.ENSMUSP00000031840Transmembrane glycoprotein NMB; Could be a melanogenic enzyme; Belongs to the PMEL/NMB family.
Tra2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000031841Transformer-2 protein homolog alpha; Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing; Belongs to the splicing factor SR family.
Npy protein networkhttps://string-db.org/network/10090.ENSMUSP00000031843C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family.
Gsdme protein networkhttps://string-db.org/network/10090.ENSMUSP00000031845Gasdermin-E, C-terminal; Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53.
Tmem213 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031851Transmembrane protein 213.
4921507P07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000031852Uncharacterized protein C7orf31 homolog.
Npvf protein networkhttps://string-db.org/network/10090.ENSMUSP00000031853Pro-FMRFamide-related neuropeptide VF; Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-i [...]
Trim24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031859Transcription intermediary factor 1-alpha; Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts w [...]
Cbx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031862Chromobox protein homolog 3; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Probably involved in the repression of ma [...]
Mtpn protein networkhttps://string-db.org/network/10090.ENSMUSP00000031866Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes c [...]
Slc13a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031868Solute carrier family 13 (sodium/sulfate symporters), member 4.
Stra8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031876Stimulated by retinoic acid gene 8 protein; Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replica [...]
Tcaf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031879TRPM8 channel-associated factor 2; Negatively regulates the plasma membrane cation channel TRPM8 activity. Involved in the recruitment of TRPM8 to the cell surface. Promotes prostate cancer cell [...]
Clcn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031894Chloride channel protein 1; Voltage-gated chloride channel (By similarity). Plays an important role in membrane repolarization in skeletal muscle cells after muscle contraction (Probable).
Casp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031895Caspase-2 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivatin [...]
Gstk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031897Glutathione S-transferase kappa 1; Belongs to the GST superfamily. Kappa family.
Sval1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031898Seminal vesicle antigen-like 1.
Kel protein networkhttps://string-db.org/network/10090.ENSMUSP00000031899Kell blood group glycoprotein homolog; Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3 (By similarity); Belongs to the peptidase M13 family.
Llcfc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031900LLLL and CFNLAS motif-containing protein 1.
Trpv5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031901Transient receptor potential cation channel subfamily V member 5; Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. Req [...]
Trpv6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031902Transient receptor potential cation channel subfamily V member 6; Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine. Important for normal Ca [...]
Prss1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031910Protease, serine, 1 (Trypsin 1); Belongs to the peptidase S1 family.
Try4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031913Pancreatic trypsin; Belongs to the peptidase S1 family.
Ccdc184 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031914Coiled-coil domain-containing protein 184.
2210010C04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000031931RIKEN cDNA 2210010C04 gene; Belongs to the peptidase S1 family.
1700074P13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000031935RIKEN cDNA 1700074P13 gene; Belongs to the peptidase S1 family.
Moxd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031937DBH-like monooxygenase protein 2.
Prss37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031967Probable inactive serine protease 37; Plays a role in male fertility. May have a role in sperm migration or binding to zona-intact eggs. Involved in the activation of the proacrosin/acrosin syste [...]
Ssbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031971Single-stranded DNA-binding protein, mitochondrial; Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA). In vitro, required to maintain the copy number of mitoc [...]
Prdm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031976PR domain zinc finger protein 5; Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone [...]
Agk protein networkhttps://string-db.org/network/10090.ENSMUSP00000031977Acylglycerol kinase, mitochondrial; Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Phos [...]
Mrps33 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003197828S ribosomal protein S33, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS33 family.
Hpgds protein networkhttps://string-db.org/network/10090.ENSMUSP00000031982Hematopoietic prostaglandin D synthase; Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhi [...]
Smarcad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031984ATP-dependent helicase SMARCAD1; DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes [...]
Mkrn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031985E3 ubiquitin-protein ligase makorin-1; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and [...]
Rab19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000031986Ras-related protein Rab-19; Belongs to the small GTPase superfamily. Rab family.
Pcyox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032065Prenylcysteine oxidase; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (By similarity); [...]
Tgfa protein networkhttps://string-db.org/network/10090.ENSMUSP00000032066Protransforming growth factor alpha; TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent c [...]
Figla protein networkhttps://string-db.org/network/10090.ENSMUSP00000032070Factor in the germline alpha; Germ-line specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-spe [...]
Dusp11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032071RNA/RNP complex-1-interacting phosphatase; Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. In addition, has phosphatase ac [...]
Nat8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032073N-acetyltransferase 8; Acetylates the free alpha-amino group of cysteine S- conjugates to form mercapturic acids. This is the final step in a major route for detoxification of a wide variety of r [...]
Nat8f5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032074Probable N-acetyltransferase CML5; May play a role in regulation of gastrulation. Belongs to the camello family.
Cct7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032078T-complex protein 1 subunit eta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex [...]
Pradc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032080Protease-associated domain-containing protein 1.
Reg3g protein networkhttps://string-db.org/network/10090.ENSMUSP00000032089Regenerating islet-derived protein 3-gamma 16.5 kDa form; Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exp [...]
Prickle2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032093Prickle-like protein 2.
Fbxl14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032094F-box/LRR-repeat protein 14; Substrate-recognition component of some (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination [...]
1700003E16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000032106Uncharacterized protein C2orf81 homolog.
Kbtbd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032107Kelch repeat and BTB domain-containing protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(K [...]
Ino80b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032109INO80 complex subunit B; Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
Wbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032111WW domain-binding protein 1.
Mogs protein networkhttps://string-db.org/network/10090.ENSMUSP00000032114Mannosyl-oligosaccharide glucosidase; Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor; Belongs to the glycosyl hydrolase 63 family.
Tacr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032122Substance-P receptor; This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger syste [...]
Mrpl19 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003212439S ribosomal protein L19, mitochondrial; Belongs to the bacterial ribosomal protein bL19 family.
Bmp10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032125Bone morphogenetic protein 10; Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KI [...]
Gkn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032127Gastrokine-3; Inhibits gastric epithelial cell proliferation.
Gkn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032128Gastrokine-2.
Gkn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032129Gastrokine-1; Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium.
Aplf protein networkhttps://string-db.org/network/10090.ENSMUSP00000032130Aprataxin and PNK-like factor; Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post- [...]
Gp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032133Platelet glycoprotein IX; The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces [...]
Cnbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000032138Cellular nucleic acid-binding protein; Single-stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression.
Rpn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032143Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Ma [...]
Frmd4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032146FERM domain-containing protein 4B; Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffoldin [...]
Eif4e3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032151Eukaryotic translation initiation factor 4E type 3; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhib [...]
Prok2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032152Prokineticin-2; May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize outpu [...]
Gxylt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032157Glucoside xylosyltransferase 2; Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of x [...]
Ruvbl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032165RuvB-like 1; Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA helicase (3' to 5') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits [...]
Sec61a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032168Protein transport protein Sec61 subunit alpha isoform 1; Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across e [...]
Abtb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032169Ankyrin repeat and BTB/POZ domain-containing protein 1; May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes (By similarity).
Chchd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032172MICOS complex subunit Mic25; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner mem [...]
Nup210 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032179Nuclear pore membrane glycoprotein 210; Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity; Belongs to the NUP210 family.
Wnt7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000032180Protein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway. Plays an important role in embryoni [...]
Xpc protein networkhttps://string-db.org/network/10090.ENSMUSP00000032182DNA repair protein complementing XP-C cells homolog; Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. [...]
Tmem43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032183Transmembrane protein 43; May have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane. Required for retaining emerin at the [...]
Slc6a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032185Sodium- and chloride-dependent taurine transporter; Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake.
Sumf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032191Formylglycine-generating enzyme; Oxidase that catalyzes the conversion of cysteine to 3- oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent. 3-oxoalanine mod [...]
Itpr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032192Inositol 1,4,5-trisphosphate receptor type 1; Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Involved i [...]
Bhlhe40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032194Class E basic helix-loop-helix protein 40; Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controll [...]
Arl8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032196ADP-ribosylation factor-like protein 8B; Plays a role in lysosome motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for [...]
Usp18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032198Ubl carboxyl-terminal hydrolase 18; Involved in the regulation of inflammatory response to interferon type 1. Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked vi [...]
Slc6a12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032200Sodium- and chloride-dependent betaine transporter; Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic [...]
Ret protein networkhttps://string-db.org/network/10090.ENSMUSP00000032201Extracellular cell-membrane anchored RET cadherin 120 kDa fragment; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, ce [...]
A2m protein networkhttps://string-db.org/network/10090.ENSMUSP00000032203Alpha-2-macroglobulin-P; Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific [...]
Klrg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032207Killer cell lectin-like receptor subfamily G member 1; Plays an inhibitory role on natural killer (NK) cells and T- cell functions upon binding to their non-MHC ligands. May mediate missing self [...]
Gdf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032211Growth/differentiation factor 3; Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and me [...]
Ptms protein networkhttps://string-db.org/network/10090.ENSMUSP00000032216Parathymosin; Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections.
Lag3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032217Secreted lymphocyte activation gene 3 protein; Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells. Delivers inhibitory signals upon binding to ligands, such as [...]
Lrrc23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032218Leucine-rich repeat-containing protein 23.
Mug1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032228Murinoglobulin-1; A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester [...]
Tuba8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032233Tubulin alpha-8 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha c [...]
Bms1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032237BMS1 homolog, ribosome assembly protein (Yeast).
Vmn2r26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032238Vomeronasal type-2 receptor 26; Putative pheromone receptor.
Clec4e protein networkhttps://string-db.org/network/10090.ENSMUSP00000032239C-type lectin domain family 4 member E; A calcium-dependent lectin that acts as a pattern recognition receptor of the innate immune system. Recognizes damage-associated molecular patterns (DAMPs) [...]
Clec4d protein networkhttps://string-db.org/network/10090.ENSMUSP00000032240C-type lectin domain family 4 member D; A calcium-dependent lectin involved in innate recognition of pathogen-associated molecular patterns (PAMPs). Interacts with signaling adapter Fc receptor g [...]
Clec4a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032248C-type lectin domain family 4 member A; May be involved in regulating immune reactivity. May play a role in modulating dendritic cells (DC) differentiation and/or maturation (By similarity). May [...]
Klrk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032252NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed [...]
Klrb1f protein networkhttps://string-db.org/network/10090.ENSMUSP00000032257Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or costimulation of IL-2 production and proliferation of T-cells in respon [...]
Clec2e protein networkhttps://string-db.org/network/10090.ENSMUSP00000032258C-type lectin domain family 2 member E; Lectin-type cell surface receptor.
Cd69 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032259Early activation antigen CD69; Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
Clec2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000032260C-type lectin domain family 2 member D; Receptor for KLRB1B that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Binds high molecular weight sulfa [...]
Clec12b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032261C-type lectin domain family 12 member B; Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphoryl [...]
Clec1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032262C-type lectin domain family 1 member B; C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN. After ligand activation, signals via sequenti [...]
Tmem52b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032263Transmembrane protein 52B.
Gabarapl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032264Gamma-aminobutyric acid receptor-associated protein-like 1; Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracell [...]
Olr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032265Oxidized low-density lipoprotein receptor 1, soluble form; Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascu [...]
Klrc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032270Killer cell lectin-like receptor subfamily C, member 1.
Adipor2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032272Adiponectin receptor protein 2; Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal body fat and glucose homeostasis. [...]
Ccdc77 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032283Coiled-coil domain-containing protein 77.
Klra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032288T-cell surface glycoprotein YE1/48; Receptor on natural killer (NK) cells for H-2d alleles. Inhibits the activity of NK cells thus preventing cell lysis.
Magohb protein networkhttps://string-db.org/network/10090.ENSMUSP00000032307Protein mago nashi homolog 2; Required for pre-mRNA splicing as component of the spliceosome. Plays a redundant role with MAGOH in the exon junction complex and in the nonsense-mediated decay (NM [...]
Ybx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032309Y-box-binding protein 3; Binds to the GM-CSF promoter. Seems to act as a repressor (By similarity). Binds also to full-length mRNA and to short RNA sequences containing the consensus site 5'-UCCA [...]
Tas2r116 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032315Taste receptor type 2 member 116; Putative taste receptor which may play a role in the perception of bitterness.
Tas2r103 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032317Taste receptor type 2 member 103; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calc [...]
Bcl2l14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032321Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis; Belongs to the Bcl-2 family.
Lrp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032322Low-density lipoprotein receptor-related protein 6; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into [...]
Ddx47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032326Probable ATP-dependent RNA helicase DDX47; Involved in apoptosis. May have a role in rRNA processing and mRNA splicing. Associates with pre-rRNA precursors (By similarity). Belongs to the DEAD bo [...]
Gprc5d protein networkhttps://string-db.org/network/10090.ENSMUSP00000032327G-protein coupled receptor family C group 5 member D; Belongs to the G-protein coupled receptor 3 family.
Atf7ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000032335Activating transcription factor 7-interacting protein 1; Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chrom [...]
Plbd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032336Phospholipase B-like 1 chain A; Exhibits weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophosph [...]
Gucy2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000032338Heat-stable enterotoxin receptor; Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activa [...]
Art4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032341Ecto-ADP-ribosyltransferase 4; Belongs to the Arg-specific ADP-ribosyltransferase family.
Mgp protein networkhttps://string-db.org/network/10090.ENSMUSP00000032342Matrix Gla protein; Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
Erp27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032343Endoplasmic reticulum resident protein 27; Specifically binds unfolded proteins and may recruit protein disulfide isomerase PDIA3 to unfolded substrates. Binds protein substrates via a hydrophobi [...]
Arhgdib protein networkhttps://string-db.org/network/10090.ENSMUSP00000032344Rho GDP-dissociation inhibitor 2; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Regulates [...]
Plcz1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000323561-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activ [...]
Slco1c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032362Solute carrier organic anion transporter family member 1C1; Mediates the Na(+)-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other pot [...]
Gys2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032371Glycogen [starch] synthase, liver; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Belongs to the glycosyltransferase 3 family.
Golt1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032372Vesicle transport protein GOT1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex; Belongs to the GOT1 family.
Ldhb protein networkhttps://string-db.org/network/10090.ENSMUSP00000032373L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family.
Lmcd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032376LIM and cysteine-rich domains protein 1; Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstrea [...]
Sspn protein networkhttps://string-db.org/network/10090.ENSMUSP00000032383Sarcospan; Component of the dystrophin-glycoprotein complex (DGC), a complex that spans the muscle plasma membrane and forms a link between the F-actin cytoskeleton and the extracellular matrix. [...]
Bhlhe41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032386Class E basic helix-loop-helix protein 41; Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controll [...]
Lrmp protein networkhttps://string-db.org/network/10090.ENSMUSP00000032396Processed lymphoid-restricted membrane protein; Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with [...]
Thumpd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032398THUMP domain-containing protein 3; Belongs to the methyltransferase superfamily.
Kras protein networkhttps://string-db.org/network/10090.ENSMUSP00000032399GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role [...]
Bcat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032402Branched-chain-amino-acid aminotransferase, cytosolic; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
Ogg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032406DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine (FAPY) [...]
Camk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032409Calcium/calmodulin-dependent protein kinase type 1; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, regu [...]
Tada3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032410Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be consid [...]
Etnk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032413Ethanolamine kinase 1; Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in phosphatidylathanolamine biosynthesis (By similarity); Belongs to the choline/ethanolami [...]
Ttll3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032414Tubulin monoglycylase TTLL3; Monoglycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues within the C-termi [...]
Cmas protein networkhttps://string-db.org/network/10090.ENSMUSP00000032419N-acylneuraminate cytidylyltransferase; Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for th [...]
St8sia1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032421Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one [...]
Creld1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032422Protein disulfide isomerase Creld1; Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane ; Belongs to the CRELD family.
Emc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032425ER membrane protein complex subunit 3; Belongs to the EMC3 family.
Ints13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032427Integrator complex subunit 13; Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucl [...]
Med21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032429Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Smco2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032433Single-pass membrane and coiled-coil domain-containing protein 2.
Sec13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032440Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles (B [...]
Ccdc91 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032441Coiled-coil domain-containing protein 91; Involved in the regulation of membrane traffic through the trans-Golgi network (TGN). Functions in close cooperation with the GGAs in the sorting of hydr [...]
Far2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032443Fatty acyl-CoA reductase 2; Catalyzes the reduction of saturated but not unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. A lower activity can be observed with shorter fatty acyl-CoA subs [...]
Slc6a11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032451Sodium- and chloride-dependent GABA transporter 3; Terminates the action of GABA by its high affinity sodium- dependent reuptake into presynaptic terminals. Can also transport beta- alanine and t [...]
Slc6a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032454Sodium- and chloride-dependent GABA transporter 1; Terminates the action of GABA by its high affinity sodium- dependent reuptake into presynaptic terminals; Belongs to the sodium:neurotransmitter [...]
Vgll4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032459Transcription cofactor vestigial-like protein 4; May act as a specific coactivator for the mammalian TEFs. Belongs to the vestigial family.
Tamm41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032461Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosyn [...]
Timp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032462Metalloproteinase inhibitor 4; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
Mbd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032469Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethyl [...]
Rho protein networkhttps://string-db.org/network/10090.ENSMUSP00000032471Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retina [...]
Klrb1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032472Killer cell lectin-like receptor subfamily B member 1B allele B; Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I [...]
Iigp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032473Interferon-inducible GTPase 1; GTPase with low activity. Has higher affinity for GDP than for GTP. Plays a role in resistance to intracellular pathogens. Required for disruption of the parasitoph [...]
Slc2a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032476Solute carrier family 2, facilitated glucose transporter member 3; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Med [...]
Necap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032477Adaptin ear-binding coat-associated protein 1; Involved in endocytosis.
Pianp protein networkhttps://string-db.org/network/10090.ENSMUSP00000032479PILR alpha-associated neural protein; Acts as a ligand for PILRA in neuronal tissues, where it may be involved in immune regulation.
Ing4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032480Inhibitor of growth protein 4; Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of hi [...]
Mrpl51 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003248539S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL51 family.
Cd27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032486CD27 antigen; Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Vamp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032487Vesicle-associated membrane protein 1; Involved in the targeting and/or fusion of transport vesicles to their target membrane; Belongs to the synaptobrevin family.
Ltbr protein networkhttps://string-db.org/network/10090.ENSMUSP00000032489Tumor necrosis factor receptor superfamily member 3; Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a r [...]
Tnfrsf1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000032491Tumor necrosis factor receptor superfamily member 1A; Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated recept [...]
Cd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032492CD9 antigen; Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Present at [...]
D6Wsu163e protein networkhttps://string-db.org/network/10090.ENSMUSP00000032497Protein C12orf4 homolog; Plays a role in mast cell degranulation.
Prmt8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032500Protein arginine N-methyltransferase 8; S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MM [...]
Tspan11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032501Tetraspanin-11.
Fkbp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032508Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed; Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction [...]
Klrb1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000032512Killer cell lectin-like receptor subfamily B member 1A; Plays a stimulatory role on natural killer (NK) cell cytotoxicity.
Clec2h protein networkhttps://string-db.org/network/10090.ENSMUSP00000032518C-type lectin domain family 2 member H; Lectin-type cell surface receptor.
Ceacam12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032520Carcinoembryonic antigen-related cell adhesion molecule 12.
Slc27a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032539Bile acyl-CoA synthetase; Acyl-CoA synthetase that catalyzes the activation of bile acids via formation of bile acid CoA thioesters which is necessary for their subsequent conjugation with glycin [...]
2900092C05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000032541RIKEN cDNA 2900092C05 gene.
Zik1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032551Zinc finger protein interacting with ribonucleoprotein K; May be a transcriptional repressor. Belongs to the krueppel C2H2-type zinc-finger protein family.
Tomm40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032555Mitochondrial import receptor subunit TOM40 homolog; Channel-forming protein essential for import of protein precursors into mitochondria.
Rtn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032559Reticulon-2.
Ppm1n protein networkhttps://string-db.org/network/10090.ENSMUSP00000032560Probable protein phosphatase 1N.
Vasp protein networkhttps://string-db.org/network/10090.ENSMUSP00000032561Vasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidanc [...]
Qpctl protein networkhttps://string-db.org/network/10090.ENSMUSP00000032566Glutaminyl-peptide cyclotransferase-like protein; Responsible for the biosynthesis of pyroglutamyl peptides. Belongs to the glutaminyl-peptide cyclotransferase family.
Dmpk protein networkhttps://string-db.org/network/10090.ENSMUSP00000032568Myotonin-protein kinase; Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation [...]
Dmwd protein networkhttps://string-db.org/network/10090.ENSMUSP00000032570Dystrophia myotonica WD repeat-containing protein.
Pglyrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032573Peptidoglycan recognition protein 1; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram- [...]
Pop4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032585Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNa [...]
Zfp12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032591Zinc finger protein 12; Transcriptional repressor which suppresses activation protein 1 (AP-1)- and serum response element (SRE)-mediated transcriptional activity.
Rpl28 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003259760S ribosomal protein L28; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL28 family.
Tubgcp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032627Gamma-tubulin complex component 5; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
Cyfip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032629Cytoplasmic FMR1-interacting protein 1; Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E- FMR1 complex this subuni [...]
Oca2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032633P protein; Could be involved in the transport of tyrosine, the precursor to melanin synthesis, within the melanocyte. Regulates the pH of melanosome and the melanosome maturation. One of the comp [...]
Zfp819 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032661Zinc finger protein 819.
Ceacam18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032663Carcinoembryonic antigen-related cell adhesion molecule 18; Belongs to the immunoglobulin superfamily. CEA family.
Siglece protein networkhttps://string-db.org/network/10090.ENSMUSP00000032667Sialic acid-binding Ig-like lectin 12; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sia [...]
Lypd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032683Ly6/PLAUR domain-containing protein 5.
Tdrd12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032701Putative ATP-dependent RNA helicase TDRD12; Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essentia [...]
Slc7a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032703B(0,+)-type amino acid transporter 1; Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). Thought to be respo [...]
Faap24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032704Fanconi anemia core complex-associated protein 24; Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induc [...]
Rhpn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032705Rhophilin-2; Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA [...]
Kctd15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032709BTB/POZ domain-containing protein KCTD15; During embryonic development, interferes with neural crest formation. Inhibits AP2 transcriptional activity by interaction with its activation domain (By [...]
Slc17a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032710Vesicular glutamate transporter 2; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic p [...]
Prmt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032715Protein arginine N-methyltransferase 3; Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins; Belongs to the class I-like SAM-binding methyl [...]
Dbx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032717Homeobox protein DBX1; Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major cl [...]
Nav3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032719Neuron navigator 3; May regulate IL2 production by T-cells. May be involved in neuron regeneration.
Tarsl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032728Threonine--tRNA ligase 2, cytoplasmic; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the [...]
Apba2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032732Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machi [...]
Mphosph10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032735U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA process [...]
Mtmr10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032736Myotubularin-related protein 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.
Chrna7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032738Neuronal acetylcholine receptor subunit alpha-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-con [...]
Hddc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032747Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1; ppGpp hydrolyzing enzyme involved in starvation response.
Unc45a protein networkhttps://string-db.org/network/10090.ENSMUSP00000032748Protein unc-45 homolog A; May act as co-chaperone for HSP90 (Potential). Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell (By s [...]
Vps33b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032749Vacuolar protein sorting-associated protein 33B; May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysos [...]
Sema4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032754Semaphorin-4B; Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons; Belongs to the semaphorin family.
Mesp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032760Mesoderm posterior protein 1; Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of th [...]
Pex11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000032761Peroxisomal membrane protein 11A; May be involved in peroxisomal proliferation and may regulate peroxisomes division. May mediate binding of coatomer proteins to the peroxisomal membrane (By simi [...]
Rhcg protein networkhttps://string-db.org/network/10090.ENSMUSP00000032766Ammonium transporter Rh type C; Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion.
Nr2f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032768COUP transcription factor 2; Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or prog [...]
Pgpep1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000032770Pyroglutamyl-peptidase 1-like protein; Belongs to the peptidase C15 family.
Ttc23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032774Tetratricopeptide repeat protein 23; Participates positively in the ciliary Hedgehog (Hh) signaling.
Ctsc protein networkhttps://string-db.org/network/10090.ENSMUSP00000032779Dipeptidyl peptidase 1 exclusion domain chain; Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase. Can degrade glucagon. Plays a role in the gener [...]
Nox4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032781NADPH oxidase 4; Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases in [...]
Zfp790 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032796Zinc finger protein 790.
Tyrobp protein networkhttps://string-db.org/network/10090.ENSMUSP00000032800TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and [...]
Zfp84 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032802Zinc finger protein 84.
Zfp30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032803Zinc finger protein 30; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
2200002D01Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000032808RIKEN cDNA 2200002D01 gene.
Yif1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032809Protein YIF1B; Belongs to the YIF1 family.
Nfkbib protein networkhttps://string-db.org/network/10090.ENSMUSP00000032815NF-kappa-B inhibitor beta; Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kapp [...]
Fbxo17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032818F-box only protein 17; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modifie [...]
Psmc4 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003282426S proteasome regulatory subunit 6B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in [...]
Mfge8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032825Lactadherin; Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched c [...]
Acan protein networkhttps://string-db.org/network/10090.ENSMUSP00000032835Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds av [...]
Det1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032839DET1 homolog; Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiqui [...]
Mrps11 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003284028S ribosomal protein S11, mitochondrial; Belongs to the universal ribosomal protein uS11 family.
Mrpl46 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003284139S ribosomal protein L46, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL46 family.
Ccdc90b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032842Coiled-coil domain-containing protein 90B, mitochondrial.
Tmem126b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032843Complex I assembly factor TMEM126B, mitochondrial; Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Participates in constructing [...]
Tmem126a protein networkhttps://string-db.org/network/10090.ENSMUSP00000032844Transmembrane protein 126A; Belongs to the TMEM126 family.
Me3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032856NADP-dependent malic enzyme, mitochondrial; Belongs to the malic enzymes family.
Fah protein networkhttps://string-db.org/network/10090.ENSMUSP00000032865Fumarylacetoacetase; Belongs to the FAH family.
Sh3gl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032874Endophilin-A3; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity); Belongs to the endophilin family.
Ddias protein networkhttps://string-db.org/network/10090.ENSMUSP00000032877DNA damage-induced apoptosis suppressor protein; May be an anti-apoptotic protein involved in DNA repair or cell survival.
Rab30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032879Ras-related protein Rab-30; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle bet [...]
Ndufc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032882NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. C [...]
Arl6ip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032888ADP-ribosylation factor-like protein 6-interacting protein 1; Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity- dependent [...]
Smg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032891Serine/threonine-protein kinase SMG1; Serine/threonine protein kinase involved in both mRNA surveillance and genotoxic stress response pathways. Recognizes the substrate consensus sequence [ST]-Q [...]
Xylt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032892Xylosyltransferase 1; Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D- xylose from UDP-D-xylose to specific serine [...]
Nucb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032895Nucleobindin-2; Calcium-binding protein which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-bin [...]
Ipo5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032898Importin-5; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the [...]
1110004F10Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000032899Small acidic protein; Belongs to the SMAP family.
Calcb protein networkhttps://string-db.org/network/10090.ENSMUSP00000032902Calcitonin gene-related peptide 2; CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points towar [...]
Calca protein networkhttps://string-db.org/network/10090.ENSMUSP00000032907Calcitonin; Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Cyp2r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032908Vitamin D 25-hydroxylase; Has a D-25-hydroxylase activity on both forms of vitamin D, vitamin D(2) and D(3); Belongs to the cytochrome P450 family.
Pde3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000032909cGMP-inhibited 3',5'-cyclic phosphodiesterase B; Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important ph [...]
Mylpf protein networkhttps://string-db.org/network/10090.ENSMUSP00000032910Myosin regulatory light chain 2, skeletal muscle isoform.
Qprt protein networkhttps://string-db.org/network/10090.ENSMUSP00000032912Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
Kif22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032915Kinesin-like protein KIF22; Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA. Plays a role [...]
Maz protein networkhttps://string-db.org/network/10090.ENSMUSP00000032916Myc-associated zinc finger protein; Transcriptional activator that binds to purine-rich GAGA sites found in the promoter of many genes including insulin I and II and islet amyloid polypeptide.
Cdipt protein networkhttps://string-db.org/network/10090.ENSMUSP00000032920CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessi [...]
Kctd13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032924BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic trans [...]
Tmem219 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032926Insulin-like growth factor-binding protein 3 receptor; Cell death receptor specific for IGFBP3, may mediate caspase- 8-dependent apoptosis upon ligand binding.
Stard10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032927START domain-containing protein 10; Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chai [...]
Fchsd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032931F-BAR and double SH3 domains protein 2; Adapter protein that plays a role in endocytosis via clathrin-coated pits. Contributes to the internalization of cell surface receptors, such as integrin I [...]
Gdpd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032944Lysophospholipase D GDPD3; Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3- phosphocholine ( [...]
Rab6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000032946Ras-related protein Rab-6A; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Involved in COPI-independent retrograde transport fro [...]
Klk7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032955Kallikrein-7; May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino ac [...]
Sgf29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032956SAGA-associated factor 29; Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and bin [...]
Ucp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032958Mitochondrial uncoupling protein 3; UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a re [...]
Nupr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032961Nuclear protein 1; Transcription regulator that converts stress signals into a program of gene expression that empowers cells with resistance to the stress induced by a change in their microenvir [...]
Ppme1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032963Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion a [...]
Lipt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032967Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes [...]
Pold3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032969DNA polymerase delta subunit 3; Accessory component of both the DNA polymerase delta complex and the DNA polymerase zeta complex (By similarity). As a component of the trimeric and tetrameric DNA [...]
Atp2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032974Sarcoplasmic/endoplasmic reticulum calcium ATPase 1; Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sa [...]
Prss8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032988Prostasin heavy chain; Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates (By similarity). Stimulates epithelial sodium channel (ENaC) activity through acti [...]
Eif3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000032992Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein [...]
Spns1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000032994Protein spinster homolog 1; Sphingolipid transporter. May be involved in necrotic or autophagic cell death (By similarity).
Lat protein networkhttps://string-db.org/network/10090.ENSMUSP00000032997Linker for activation of T-cells family member 1; Required for TCR (T-cell antigen receptor)- and pre-TCR- mediated signaling, both in mature T-cells and during their development. Involved in FCG [...]
Rps3 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003299840S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit (By similarity). Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves p [...]
Il21r protein networkhttps://string-db.org/network/10090.ENSMUSP00000033000Interleukin-21 receptor; This is a receptor for interleukin-21.
Dgat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033001Diacylglycerol O-acyltransferase 2; Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substr [...]
Il4ra protein networkhttps://string-db.org/network/10090.ENSMUSP00000033004Soluble interleukin-4 receptor subunit alpha; Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiat [...]
Nsmce1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033006Non-structural maintenance of chromosomes element 1 homolog; RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transf [...]
Psma1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033008Proteasome subunit alpha type-1; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles w [...]
Thap12 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003300952 kDa repressor of the inhibitor of the protein kinase; Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulti [...]
Kdm8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033010Bifunctional peptidase and arginyl-hydroxylase JMJD5; Bifunctional enzyme that acts both as an endopeptidase and 2- oxoglutarate-dependent monoxygenase. Endopeptidase that cleaves histones N-term [...]
Copb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033012Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynth [...]
Far1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033018Fatty acyl-CoA reductase 1; Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. It plays an essential role in the production of ether lipids/plasmalo [...]
Acer3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033020Alkaline ceramidase 3; Endoplasmic reticulum and Golgi ceramidase that catalyzes the hydrolysis of unsaturated long-chain C18:1-, C20:1- and C20:4- ceramides, dihydroceramides and phytoceramides [...]
Lcmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033025Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs t [...]
Parva protein networkhttps://string-db.org/network/10090.ENSMUSP00000033030Alpha-parvin; Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishement of cell polarity, cell adhesion, cell sp [...]
Slc5a11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033035Sodium/myo-inositol cotransporter 2; Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and ab [...]
Dkk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033036Dickkopf-related protein 3; Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes inte [...]
Pak1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033040Serine/threonine-protein kinase PAK 1; Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton d [...]
BC017158 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033044RUS1 family protein C16orf58 homolog; Belongs to the RUS1 family.
Cox6a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033049Cytochrome c oxidase subunit 6A2, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The r [...]
Lyve1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033050Lymphatic vessel endothelial hyaluronic acid receptor 1; Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulati [...]
Itgad protein networkhttps://string-db.org/network/10090.ENSMUSP00000033051Integrin alpha-D; Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood [...]
Itgax protein networkhttps://string-db.org/network/10090.ENSMUSP00000033053Integrin alpha-X; Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is espe [...]
Adm protein networkhttps://string-db.org/network/10090.ENSMUSP00000033054Proadrenomedullin N-20 terminal peptide; AM and PAMP are potent hypotensive and vasodilatator agents; Belongs to the adrenomedullin family.
Pycard protein networkhttps://string-db.org/network/10090.ENSMUSP00000033056Apoptosis-associated speck-like protein containing a CARD; Functions as key mediator in apoptosis and inflammation. Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also [...]
Dkkl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033057Dickkopf-like protein 1; Involved in fertilization by facilitating sperm penetration of the zona pellucida. May promote spermatocyte apoptosis, thereby limiting sperm production. In adults, may r [...]
Sbf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033058Myotubularin-related protein 13; Guanine nucleotide exchange factor (GEF) which activates RAB21 and possibly RAB28 (By similarity). Promotes the exchange of GDP to GTP, converting inactive GDP-bo [...]
Cd37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033063Leukocyte antigen CD37; Belongs to the tetraspanin (TM4SF) family.
Kat8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033070Histone acetyltransferase KAT8; Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acet [...]
Vkorc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033074Vitamin K epoxide reductase complex subunit 1; Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide t [...]
Stx4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000033075Syntaxin-4; Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 [...]
Fbxl19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033081F-box/LRR-repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity). Binds to DNA containing unmethylated cytidine-p [...]
Bax protein networkhttps://string-db.org/network/10090.ENSMUSP00000033093Apoptosis regulator BAX; Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergo [...]
Prr14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033095Proline-rich protein 14; Functions in tethering peripheral heterochromatin to the nuclear lamina during interphase, possibly through the interaction with heterochromatin protein CBX5/HP1 alpha (B [...]
Bcat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033098Branched-chain-amino-acid aminotransferase, mitochondrial; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also fun [...]
Fgf21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033099Fibroblast growth factor 21; Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity pr [...]
Izumo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033100Izumo sperm-egg fusion protein 1; Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a [...]
Nomo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033121Nodal modulator 1; May antagonize Nodal signaling.
Abcc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033123ATP-binding cassette, sub-family C (CFTR/MRP), member 8.
Sergef protein networkhttps://string-db.org/network/10090.ENSMUSP00000033127Secretion-regulating guanine nucleotide exchange factor; Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.
Lamtor1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033131Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth [...]
Rgs10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033133Regulator of G-protein signaling 10; Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transd [...]
Bag3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033136BAG family molecular chaperone regulator 3; Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 p [...]
Ate1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033139Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradatio [...]
Ptpn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033142Tyrosine-protein phosphatase non-receptor type 5; May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family k [...]
Cpxm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033149Inactive carboxypeptidase-like protein X2; May be involved in cell-cell interactions.
Chp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033152Calcineurin B homologous protein 2; Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Binds to and activates SLC9A1/NHE1 in [...]
Ern2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033153Serine/threonine-protein kinase/endoribonuclease IRE2; Role in expression of the DDIT3 transcription factor, required for the unfolded-protein response, growth arrest and apoptosis. Has no effect [...]
Plk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033154Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome matura [...]
Dctn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033156Dynactin subunit 5; Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
Ndufab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033157Acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). Accessory and non-catalytic subunit of the mitochondrial membrane respirat [...]
Ubfd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033158Ubiquitin domain-containing protein UBFD1.
Ears2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033159Probable glutamate--tRNA ligase, mitochondrial; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferre [...]
Gga2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033160ADP-ribosylation factor-binding protein GGA2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathr [...]
Scnn1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000033161Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and w [...]
Mettl9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033163Methyltransferase-like protein 9.
Mfsd13b protein networkhttps://string-db.org/network/10090.ENSMUSP00000033166Major facilitator superfamily domain-containing 13B.
Cdr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033169Cerebellar degeneration-related protein 2.
Polr3e protein networkhttps://string-db.org/network/10090.ENSMUSP00000033173DNA-directed RNA polymerase III subunit RPC5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific periphje [...]
Uqcrc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033176Cytochrome b-c1 complex subunit 2, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport [...]
Pdzd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033178PDZ domain-containing protein 9.
Vwa3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000033180Von Willebrand factor A domain-containing protein 3A.
Ilk protein networkhttps://string-db.org/network/10090.ENSMUSP00000033182Integrin-linked protein kinase; Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein p [...]
Tpp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033184Tripeptidyl-peptidase 1; Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products pro [...]
Hpx protein networkhttps://string-db.org/network/10090.ENSMUSP00000033185Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Cnga4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033187Cyclic nucleotide-gated cation channel alpha-4; Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory [...]
Cckbr protein networkhttps://string-db.org/network/10090.ENSMUSP00000033189Gastrin/cholecystokinin type B receptor; Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, [...]
Crym protein networkhttps://string-db.org/network/10090.ENSMUSP00000033198Ketimine reductase mu-crystallin; Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyro [...]
Anks4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000033201Ankyrin repeat and SAM domain-containing protein 4B; As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organiza [...]
Zp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033207Processed zona pellucida sperm-binding protein 2; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and [...]
Tmem159 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033210Promethin.
Trim30d protein networkhttps://string-db.org/network/10090.ENSMUSP00000033211Tripartite motif-containing 30D.
Rexo5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033218RNA exonuclease 5.
Hbb-y protein networkhttps://string-db.org/network/10090.ENSMUSP00000033229Hemoglobin subunit epsilon-Y2; Hemoglobin epsilon chain is a beta-type chain found in early embryos; Belongs to the globin family.
Tha1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033230L-threonine aldolase.
Thumpd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033236THUMP domain-containing protein 1; Functions as a tRNA-binding adapter to mediate NAT10- dependent tRNA acetylation; Belongs to the THUMPD1 family.
Lhpp protein networkhttps://string-db.org/network/10090.ENSMUSP00000033241Phospholysine phosphohistidine inorganic pyrophosphate phosphatase; Phosphatase that hydrolyzes imidodiphosphate, 3- phosphohistidine and 6-phospholysine. Has broad substrate specificity and can [...]
Gp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033255Pancreatic secretory granule membrane major glycoprotein GP2.
Eef1akmt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033257EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase s [...]
Umod protein networkhttps://string-db.org/network/10090.ENSMUSP00000033263Uromodulin, secreted form; [Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes [...]
Trim21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033264E3 ubiquitin-protein ligase TRIM21; E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with [...]
Pdilt protein networkhttps://string-db.org/network/10090.ENSMUSP00000033267Protein disulfide-isomerase-like protein of the testis; Probable redox-inactive chaperone involved in spermatogenesis.
Tex36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033275Testis-expressed 36.
Uros protein networkhttps://string-db.org/network/10090.ENSMUSP00000033276Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leadin [...]
Mmp21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033278Matrix metalloproteinase-21; Plays a specialized role in the generation of left-right asymmetry during embryogenesis. May act as a negative regulator of the NOTCH-signaling pathway. Cleaves alpha [...]
Bccip protein networkhttps://string-db.org/network/10090.ENSMUSP00000033282BRCA2 and CDKN1A-interacting protein; During interphase, required for microtubule organizing and anchoring activities. During mitosis, required for the organization and stabilization of the spind [...]
Rrm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033283Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; [...]
Stim1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033289Stromal interaction molecule 1; Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endo [...]
Dhx32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033290Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32.
Art1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033300GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1; Has ADP-ribosyltransferase activity toward GLP1R. Belongs to the Arg-specific ADP-ribosyltransferase family.
Mki67 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033310Proliferation marker protein Ki-67; Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitot [...]
Atp6ap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033313Renin receptor extracellular fragment; Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the proton- transporting vacuolar (V)-ATPa [...]
Swap70 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033325Switch-associated protein 70; Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase rece [...]
Wee1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033326Wee1-like protein kinase; Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onse [...]
Nrip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033331Nuclear receptor-interacting protein 3.
Tmem9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000033333Transmembrane protein 9B; Enhances production of proinflammatory cytokines induced by TNF, IL1B, and TLR ligands. Has a role in TNF activation of both the NF-kappaB and MAPK pathways.
Akip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033335A-kinase-interacting protein 1; Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRK [...]
Tub protein networkhttps://string-db.org/network/10090.ENSMUSP00000033341Tubby protein; Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May [...]
Eif3f protein networkhttps://string-db.org/network/10090.ENSMUSP00000033342Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein [...]
Rp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033372Protein XRP2; Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium memb [...]
Cdk16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033380Cyclin-dependent kinase 16; Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Can phosphorylate CCNY at 'Ser-336' (in vitro) (By similarity). Plays a role i [...]
Usp11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033383Ubiquitin carboxyl-terminal hydrolase 11; Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasom [...]
Mrgprf protein networkhttps://string-db.org/network/10090.ENSMUSP00000033386Mas-related G-protein coupled receptor member F; Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain [...]
Fgf15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033389Fibroblast growth factor 15; Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression; Belongs to the heparin-binding growth factors family.
Fadd protein networkhttps://string-db.org/network/10090.ENSMUSP00000033394FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-ind [...]
Slc6a14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033414Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+); Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/ [...]
Nadsyn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033415Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
Il13ra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033418Interleukin-13 receptor subunit alpha-1; Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory prote [...]
Dock11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033419Dedicator of cytokinesis protein 11; Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is ass [...]
Sash3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033427SAM and SH3 domain-containing protein 3; May function as a signaling adapter protein in lymphocytes.
Rab33a protein networkhttps://string-db.org/network/10090.ENSMUSP00000033430Ras-related protein Rab-33A; Belongs to the small GTPase superfamily. Rab family.
Rbmx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033433RNA-binding motif protein, X-linked 2; Involved in pre-mRNA splicing as component of the activated spliceosome.
Igsf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033442Immunoglobulin superfamily member 1; Seems to be a coreceptor in inhibin signaling, but seems not to be a high-affinity inhibin receptor. Antagonizes activin A signaling in the presence or absenc [...]
Stk26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033444Serine/threonine-protein kinase 26; Mediator of cell growth. Modulates apoptosis. In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activatio [...]
1700080O16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000033449RIKEN cDNA 1700080O16 gene.
Gpc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033450Secreted glypican-4; Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system.
3830403N18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000033458RIKEN cDNA 3830403N18 gene.
Slc9a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033463Sodium/hydrogen exchanger 9; May act in electroneutral exchange of protons for Na(+) across membranes. Involved in the effusion of Golgi luminal H(+) in exchange for cytosolic cations. Involved i [...]
Brs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033464Bombesin receptor subtype-3; Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium se [...]
Vgll1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033465Transcription cofactor vestigial-like protein 1; May act as a specific coactivator for the mammalian TEFs. Belongs to the vestigial family.
Cd40lg protein networkhttps://string-db.org/network/10090.ENSMUSP00000033466CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells [...]
Arhgef6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033468Rho guanine nucleotide exchange factor 6; Acts as a RAC1 guanine nucleotide exchange factor (GEF).
Fgf13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033473Fibroblast growth factor 13; Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, [...]
F9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033477Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in [...]
Ccdc22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033483Coiled-coil domain-containing protein 22; Involved in regulation of NF-kappa-B signaling. Promotes ubiquitination of I-kappa-B-kinase subunit IKBKB and its subsequent proteasomal degradation lead [...]
Prickle3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033485Prickle planar cell polarity protein 3; Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gas [...]
Plp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033486Proteolipid protein 2; May play a role in cell differentiation in the intestinal epithelium.
Praf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033489PRA1 family protein 2; May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptotic role in cerulenin-induced neuroblastoma apoptosis (By similarity).
Ccdc120 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033490Coiled-coil domain-containing protein 120; Centriolar protein required for centriole subdistal appendage assembly and microtubule anchoring in interphase cells. Together with CCDC68, cooperate wi [...]
Timm17b protein networkhttps://string-db.org/network/10090.ENSMUSP00000033498Mitochondrial import inner membrane translocase subunit Tim17-B; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across [...]
Eras protein networkhttps://string-db.org/network/10090.ENSMUSP00000033500GTPase ERas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells.
Hdac6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033501Histone deacetylase 6; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic rep [...]
Gata1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033502Erythroid transcription factor; Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequenc [...]
Glod5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033503Glyoxalase domain-containing protein 5; Belongs to the glyoxalase I family.
Was protein networkhttps://string-db.org/network/10090.ENSMUSP00000033505Wiskott-Aldrich syndrome protein homolog; Effector protein for Rho-type GTPases that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient a [...]
Wdr13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033506WD repeat-containing protein 13.
Ebp protein networkhttps://string-db.org/network/10090.ENSMUSP000000335093-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase; Catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers; Belongs to the EBP family.
Slc38a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033512Sodium-coupled neutral amino acid transporter 5; Functions as a sodium-dependent amino acid transporter which countertransport protons. Mediates the saturable, pH-sensitive, and electrogenic cotr [...]
Ftsj1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033513Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
Dynlt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033519Dynein light chain Tctex-type 3; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to a [...]
3830417A13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000033522RIKEN cDNA 3830417A13 gene.
Ctag2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033524Cancer/testis antigen 2.
4930447F04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000033525RIKEN cDNA 4930447F04 gene.
Aff2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033532AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure; Belongs to the AF4 family.
4931400O07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000033537RIKEN cDNA 4931400O07 gene.
F8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033539Coagulation factor VIII; Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.
Vbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033540Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which the [...]
Fundc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033541FUN14 domain-containing protein 2; Belongs to the FUN14 family.
Mtcp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033542Protein p13 MTCP-1; Enhances the phosphorylation and activation of AKT1 and AKT2.
Cmc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033543Cx9C motif-containing protein 4.
Brcc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033544Lys-63-specific deubiquitinase BRCC36; Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Componen [...]
Rab39b protein networkhttps://string-db.org/network/10090.ENSMUSP00000033545Ras-related protein Rab-39B; Small GTPases Rab involved in autophagy. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to t [...]
Asb12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033549Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquit [...]
Heph protein networkhttps://string-db.org/network/10090.ENSMUSP00000033553Hephaestin; May function as a ferroxidase for ferrous (II) to ferric ion (III) conversion and may be involved in copper transport and homeostasis. Implicated in iron homeostasis and may mediate i [...]
Gpr165 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033554G-protein coupled receptor 165; Belongs to the G-protein coupled receptor 1 family.
Pgr15l protein networkhttps://string-db.org/network/10090.ENSMUSP00000033556G protein-coupled receptor 15-like; Belongs to the G-protein coupled receptor 1 family.
Ophn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033560Oligophrenin-1; Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in s [...]
Awat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033567Acyl-CoA wax alcohol acyltransferase 2; Acyltransferase that catalyzes the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters. Shows a preference for mediu [...]
Igbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033570Immunoglobulin-binding protein 1; Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP [...]
Magee2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033575Melanoma antigen, family E, 2.
Pbdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033577Protein PBDC1.
Fgf16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033581Fibroblast growth factor 16; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferatio [...]
Cox7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000033582Cytochrome c oxidase subunit 7B, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The re [...]
Pgk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033585Phosphoglycerate kinase 2; Essential for sperm motility and male fertility but is not required for the completion of spermatogenesis.
Itm2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000033591Integral membrane protein 2A; Belongs to the ITM2 family.
Hmgn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033597High mobility group nucleosome-binding domain-containing protein 5; Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin com [...]
Sh3bgrl protein networkhttps://string-db.org/network/10090.ENSMUSP00000033598SH3 domain-binding glutamic acid-rich-like protein; Belongs to the SH3BGR family.
Tnmd protein networkhttps://string-db.org/network/10090.ENSMUSP00000033602Tenomodulin; May be an angiogenesis inhibitor; Belongs to the chondromodulin-1 family.
Sytl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033608Synaptotagmin-like protein 4; Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phosph [...]
Cstf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033609Cleavage stimulation factor subunit 2; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre [...]
Nox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033610NADPH oxidase 1; Pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism.
Xkrx protein networkhttps://string-db.org/network/10090.ENSMUSP00000033611XK-related protein 2.
Btk protein networkhttps://string-db.org/network/10090.ENSMUSP00000033617Tyrosine-protein kinase BTK; Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) trigge [...]
4930513O06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000033625RIKEN cDNA 4930513O06 gene.
Serpina7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033626Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family.
Acsl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033634Long-chain-fatty-acid--CoA ligase 4; Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation. Pr [...]
Dcx protein networkhttps://string-db.org/network/10090.ENSMUSP00000033642Neuronal migration protein doublecortin; Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by comp [...]
Glt28d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033643Glycosyltransferase 28 domain-containing 2.
Il13ra2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033646Interleukin-13 receptor subunit alpha-2; Binds as a monomer with high affinity to interleukin-13 (IL13); Belongs to the type I cytokine receptor family. Type 5 subfamily.
Rs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033650Retinoschisin; Binds negatively charged membrane lipids, such as phosphatidylserine and phosphoinositides. May play a role in cell-cell adhesion processes in the retina, via homomeric interaction [...]
Phka2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033652Phosphorylase b kinase regulatory subunit alpha, liver isoform; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bin [...]
Pdha1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033662Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereb [...]
Il2rg protein networkhttps://string-db.org/network/10090.ENSMUSP00000033664Cytokine receptor common subunit gamma; Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis [...]
Map3k15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033665Mitogen-activated protein kinase kinase kinase 15; May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis.
Rps6ka3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033671Ribosomal protein S6 kinase alpha-3; Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the [...]
Nono protein networkhttps://string-db.org/network/10090.ENSMUSP00000033673Non-POU domain-containing octamer-binding protein; DNA- and RNA binding protein, involved in several nuclear processes. Binds the conventional octamer sequence in double-stranded DNA. Also binds [...]
Itgb1bp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033674Integrin beta-1-binding protein 2; May play a role during maturation and/or organization of muscles cells.
Rps4x protein networkhttps://string-db.org/network/10090.ENSMUSP0000003368340S ribosomal protein S4, X isoform; Belongs to the eukaryotic ribosomal protein eS4 family.
Dmrtc1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000033686Doublesex- and mab-3-related transcription factor C1.
Cdx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033689Homeobox protein CDX-4.
Tsx protein networkhttps://string-db.org/network/10090.ENSMUSP00000033691Testis-specific protein TSX; May have an RNA/DNA binding role.
Zcchc13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033692Cellular nucleic acid binding-like protein.
Abcb7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033695ATP-binding cassette sub-family B member 7, mitochondrial; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iro [...]
Gabrq protein networkhttps://string-db.org/network/10090.ENSMUSP00000033711Gamma-aminobutyric acid receptor subunit theta; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor an [...]
Nsdhl protein networkhttps://string-db.org/network/10090.ENSMUSP00000033715Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Involved in the sequential removal of two C-4 methyl groups in post-squalene cholesterol biosynthesis.
Rbbp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033720Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a mann [...]
Arhgap6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033721Rho GTPase-activating protein 6; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin [...]
Syap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033723Synapse-associated protein 1; Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation.
Ctps2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033727CTP synthase 2; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine [...]
Grpr protein networkhttps://string-db.org/network/10090.ENSMUSP00000033730Gastrin-releasing peptide receptor; Receptor for gastrin-releasing peptide (GRP). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, res [...]
Zfp275 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033731Zinc finger protein 275.
Haus7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033737HAUS augmin-like complex subunit 7; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex; Belongs to [...]
Trex2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033738Three prime repair exonuclease 2; Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.
Car5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000033739Carbonic anhydrase 5B, mitochondrial; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family.
Zfp92 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033740Zinc finger protein 92; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Bgn protein networkhttps://string-db.org/network/10090.ENSMUSP00000033741Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
Pir protein networkhttps://string-db.org/network/10090.ENSMUSP00000033749Pirin; Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox- state-dependent manner. May be required for efficient termina [...]
Vegfd protein networkhttps://string-db.org/network/10090.ENSMUSP00000033751Vascular endothelial growth factor D; Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on th [...]
Slc6a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033752Sodium- and chloride-dependent creatine transporter 1; Required for the uptake of creatine. Plays an important role in supplying creatine to the brain via the blood-brain barrier.
Asb9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033756Ankyrin repeat and SOCS box protein 9; Substrate-recognition component of a SCF-like ECS (Elongin- Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination a [...]
Hcfc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033761HCF C-terminal chain 1; Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its abilit [...]
Naa10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033763N-alpha-acetyltransferase 10; Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. Acetylates amino termini that ar [...]
Avpr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033765Vasopressin V2 receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption (By simi [...]
Irak1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033769Interleukin-1 receptor-associated kinase 1; Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like recept [...]
Mecp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033770Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. M [...]
Opn1mw protein networkhttps://string-db.org/network/10090.ENSMUSP00000033771Medium-wave-sensitive opsin 1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. May increase spectral [...]
Mpp1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003377555 kDa erythrocyte membrane protein; Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PI [...]
Dkc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033776H/ACA ribonucleoprotein complex subunit DKC1; Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the iso [...]
Tceal6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033783Transcription elongation factor A (SII)-like 6.
Morf4l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033797Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosoma [...]
Plp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033800Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin; [...]
Zcchc18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033804Zinc finger CCHC domain-containing protein 18; Belongs to the ZCCHC12 family.
Psmd10 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003380526S proteasome non-ATPase regulatory subunit 10; Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the b [...]
Vsig1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033806V-set and immunoglobulin domain-containing protein 1.
Prps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033809Ribose-phosphate pyrophosphokinase 1; Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
F7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033820Coagulation factor VII; Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, [...]
F10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033821Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting [...]
Proz protein networkhttps://string-db.org/network/10090.ENSMUSP00000033822Vitamin K-dependent protein Z; Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa i [...]
Lamp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033824Lysosome-associated membrane glycoprotein 1; Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
Adprhl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033825[Protein ADP-ribosylarginine] hydrolase-like protein 1; Seems not to catalyse the hydrolysis of O-acetyl-ADP-ribose.
Atp4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000033826Potassium-transporting ATPase subunit beta; Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial [...]
Grk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033827Rhodopsin kinase GRK1; Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. [...]
Gas6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033828Growth arrest-specific protein 6; Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6 [...]
Coprs protein networkhttps://string-db.org/network/10090.ENSMUSP00000033839Coordinator of PRMT5 and differentiation stimulator; Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation [...]
Myom2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033842Myomesin 2.
Angpt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033846Angiopoietin-2; Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence [...]
Defb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033852Beta-defensin 3; Antimicrobial activity against Gram-negative bacteria E.coli and P.aeruginosa; Belongs to the beta-defensin family. LAP/TAP subfamily.
Defb8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033854Beta-defensin 8; A synthetic peptide displays antimicrobial activities against S.aureus, P.aeruginosa, E.coli and B.cepacia. The antimicrobial activity against S.aureus, E.coli and B.cepacia is r [...]
Vps36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033866Vacuolar protein-sorting-associated protein 36; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation [...]
Slc25a15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033871Mitochondrial ornithine transporter 1; Ornithine-citrulline antiporter. Connects the cytosolic and the intramitochondrial reactions of the urea cycle by exchanging cytosolic ornithine with matrix [...]
Erlin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033873Erlin-2; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5- trisphosphate receptors (IP3Rs) such as ITPR1. Promotes s [...]
Plpbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000033875Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active f [...]
Adgra2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033876Adhesion G protein-coupled receptor A2; Endothelial receptor which functions together with RECK to enable brain endothelial cells to selectively respond to Wnt7 signals (WNT7A or WNT7B). Plays a [...]
Brf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033877Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements u [...]
Eif4ebp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033880Eukaryotic translation initiation factor 4E-binding protein 1; Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphoryla [...]
Chrna6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033882Neuronal acetylcholine receptor subunit alpha-6; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-con [...]
Cd209e protein networkhttps://string-db.org/network/10090.ENSMUSP00000033888CD209 antigen-like protein E; Putative pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments.
Col4a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033898Collagen alpha-1(IV) chain; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and [...]
Col4a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033899Collagen alpha-2(IV) chain; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and [...]
Rab20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033900Ras-related protein Rab-20; Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and Mycobacterium. [...]
Naxd protein networkhttps://string-db.org/network/10090.ENSMUSP00000033901ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which cataly [...]
Ankrd10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033905Ankyrin repeat domain-containing protein 10.
1700016D06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000033906RIKEN cDNA 1700016D06 gene.
Tex29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033909Testis-expressed protein 29.
Leprotl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033910Leptin receptor overlapping transcript-like 1; Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of redu [...]
Gpm6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000033915Neuronal membrane glycoprotein M6-a; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in n [...]
Spata4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033917Spermatogenesis-associated protein 4; May play a role in apoptosis regulation.
Asb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033918Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquiti [...]
Vegfc protein networkhttps://string-db.org/network/10090.ENSMUSP00000033919Vascular endothelial growth factor C; Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of [...]
Aga protein networkhttps://string-db.org/network/10090.ENSMUSP00000033920N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase; Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. Belongs to the Ntn-hydrolase family.
Eri1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000339273'-5' exoribonuclease 1; RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and [...]
Tnks protein networkhttps://string-db.org/network/10090.ENSMUSP00000033929Poly [ADP-ribose] polymerase tankyrase-1; Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of [...]
Dusp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033930Dual specificity protein phosphatase 4; Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
Saraf protein networkhttps://string-db.org/network/10090.ENSMUSP00000033933Store-operated calcium entry-associated regulatory factor; Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic [...]
Mrps31 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003393428S ribosomal protein S31, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS31 family.
Dkk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033936Dickkopf-related protein 4; Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes inte [...]
Polb protein networkhttps://string-db.org/network/10090.ENSMUSP00000033938DNA polymerase beta; Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts a [...]
Ikbkb protein networkhttps://string-db.org/network/10090.ENSMUSP00000033939Inhibitor of nuclear factor kappa-B kinase subunit beta; Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory [...]
Plat protein networkhttps://string-db.org/network/10090.ENSMUSP00000033941Tissue-type plasminogen activator chain A; Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated [...]
Gins4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033950DNA replication complex GINS protein SLD5, N-terminally processed; The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 i [...]
Sfrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033952Secreted frizzled-related protein 1; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell gr [...]
Ido1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033956Indoleamine 2,3-dioxygenase 1; Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway. Involved in the peripheral immune [...]
Adam18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033957Disintegrin and metalloproteinase domain-containing protein 18; Sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-l [...]
Adam3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033958A disintegrin and metallopeptidase domain 3; Involved in fertilization by controlling sperm migration into oviduct.
Tm2d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033961TM2 domain-containing protein 2.
Tenm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033965Teneurin-3; Involved in neural development by regulating the establishment of proper connectivity within the nervous system. Acts in both pre- and postsynaptic neurons in the hippocampus to contr [...]
Rwdd4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000033973RWD domain-containing protein 4.
Ddhd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033975Phospholipase DDHD2; Phospholipase that hydrolyzes preferentially phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid, and phosphatidylethanolamine. Specifically binds to phosphatidyli [...]
Star protein networkhttps://string-db.org/network/10090.ENSMUSP00000033979Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Transporter that binds to and tr [...]
Mak16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033983Protein MAK16 homolog.
Wrn protein networkhttps://string-db.org/network/10090.ENSMUSP00000033991Werner syndrome ATP-dependent helicase homolog; Multifunctional enzyme that has both magnesium and ATP- dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA [...]
Gsr protein networkhttps://string-db.org/network/10090.ENSMUSP00000033992Glutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol.
Rbpms protein networkhttps://string-db.org/network/10090.ENSMUSP00000033995RNA-binding protein with multiple splicing; Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to inc [...]
Frg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000033999Protein FRG1; Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transp [...]
Asah1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034000Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH. Ceramides, sphingosine, and its phosphorylated form [...]
Fgl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034003Fibrinogen-like protein 1; Immune suppressive molecule that inhibits antigen-specific T- cell activation by acting as a major ligand of LAG3. Responsible for LAG3 T-cell inhibitory function. Bind [...]
Pdgfrl protein networkhttps://string-db.org/network/10090.ENSMUSP00000034004Platelet-derived growth factor receptor-like protein.
Fgf20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034014Fibroblast growth factor 20; Neurotrophic factor that regulates central nervous development and function.
Msmo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034015Methylsterol monooxygenase 1; Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol; Belongs to the sterol desaturase family.
Klhl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034017Kelch-like protein 2; Promotes growth of cell projections in oligodendrocyte precursors. Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4 (By similarity). Compone [...]
Galnt7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034021N-acetylgalactosaminyltransferase 7; Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D- galactosamine residue to an already [...]
Sap30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034022Histone deacetylase complex subunit SAP30; Involved in the functional recruitment of the Sin3-histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of tr [...]
Scrg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034023Scrapie-responsive protein 1; Belongs to the SCRG1 family.
Hpgd protein networkhttps://string-db.org/network/10090.ENSMUSP0000003402615-hydroxyprostaglandin dehydrogenase [NAD(+)]; Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent [...]
Ednra protein networkhttps://string-db.org/network/10090.ENSMUSP00000034029Endothelin-1 receptor; Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of bindin [...]
Tmem184c protein networkhttps://string-db.org/network/10090.ENSMUSP00000034030Transmembrane protein 184C; Possible tumor suppressor which may play a role in cell growth.
Irf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034041Interferon regulatory factor 2; Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses thos [...]
Cenpu protein networkhttps://string-db.org/network/10090.ENSMUSP00000034045Centromere protein U; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segre [...]
Acsl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034046Long-chain-fatty-acid--CoA ligase 1; Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (B [...]
Cfap97 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034048Cilia- and flagella-associated protein 97; Belongs to the CFAP97 family.
Slc25a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034049ADP/ATP translocase 1; Involved in mitochondrial ADP/ATP transport. Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane; Belongs to the mitoch [...]
Ufsp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034051Ufm1-specific protease 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Do [...]
Anxa10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034052Annexin A10; Belongs to the annexin family.
Pdlim3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034053PDZ and LIM domain protein 3; May play a role in the organization of actin filament arrays within muscle cells.
Tlr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034056Toll-like receptor 3; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific [...]
Cbr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034058Carbonyl reductase family member 4; The heterotetramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid bi [...]
Sh3rf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034060E3 ubiquitin-protein ligase SH3RF1; Has E3 ubiquitin-protein ligase activity. In the absence of an external substrate, it can catalyze self-ubiquitination. Stimulates ubiquitination of potassium [...]
F11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034064Coagulation factor XIa heavy chain; Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
N4bp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034074NEDD4-binding protein 1; Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquiti [...]
Cbln1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034076[des-Ser1]-cerebellin; Required for synapse integrity and synaptic plasticity. During cerebellar synapse formation, essential for the matching and maintenance of pre- and post-synaptic elements a [...]
Heatr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034079HEAT repeat-containing protein 3.
Brd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034085Bromodomain-containing protein 7; Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Transcriptional corepressor that down- regulates the expression of target g [...]
Nkd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034086Protein naked cuticle homolog 1; Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for sp [...]
Snx20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034087Sorting nexin-20; May play a role in cellular vesicle trafficking. Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalizati [...]
Sall1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034090Sal-like protein 1; Transcriptional repressor involved in organogenesis. Essential for ureteric bud invasion in kidney development. Homozygous deletion of SALL1 results in an incomplete ureteric [...]
Rbl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034091Retinoblastoma-like protein 2; Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of con [...]
Eif2ak3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034093Eukaryotic translation initiation factor 2-alpha kinase 3; Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2- alph [...]
Gins3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034094DNA replication complex GINS protein PSF3; The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind pref [...]
Setd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034096N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF- kappa-B transcription factor [...]
Got2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034097Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabo [...]
Slc10a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034111Sodium/bile acid cotransporter 7; Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper [...]
Pou4f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034115POU domain, class 4, transcription factor 2; Tissue-specific DNA-binding transcription factor involved in the development and differentiation of target cells. Functions either as activator or rep [...]
Man2b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034121Lysosomal alpha-mannosidase; Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover; Belongs to the glycosyl hydrolase 38 family.
Vps35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034131Vacuolar protein sorting-associated protein 35; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective [...]
Orc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034132Origin recognition complex subunit 6; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define ori [...]
Mylk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034133Myosin light chain kinase 3; Kinase that phosphorylates MYL2 in vitro. Has been proposed to be calmodulin-dependent , although MYL2 phosphorylation has also been observed in the presence or absen [...]
Gpt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034136Alanine aminotransferase 2; Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.
Dnaja2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034138DnaJ homolog subfamily A member 2; Co-chaperone of Hsc70. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro).
Itfg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034140T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model.
Lonp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034141Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type [...]
Ucp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034146Mitochondrial brown fat uncoupling protein 1; Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non- [...]
Zfp330 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034147Zinc finger protein 330; Belongs to the NOA36 family.
Il15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034148Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R g [...]
Txnl4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000034159Thioredoxin-like protein 4B; Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition (By similarity).
Pmfbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034162Polyamine-modulated factor 1-binding protein 1; Required for normal spermatogenesis. It functions as a scaffold protein that attaches the sperm head-tail connecting piece to the nuclear envelope, [...]
Zfp821 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034163Zinc finger protein 821; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Ist1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034164IST1 homolog; ESCRT-III-like protein involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in [...]
Ces1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000034172Carboxylesterase 1D; Major lipase in white adipose tissue. Involved in the metabolism of xenobiotics and of natural substrates. Hydrolyzes triacylglycerols and monoacylglycerols, with a preferenc [...]
Ces1e protein networkhttps://string-db.org/network/10090.ENSMUSP00000034173Carboxylesterase 1E; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs.
Ces1f protein networkhttps://string-db.org/network/10090.ENSMUSP00000034178Carboxylesterase 1F; Hydrolyzes p-nitrophenyl butyrate (PNPB), triacylglycerol and monoacylglycerol. Shows higher activity against PNPB, a short-chain fatty acid ester, than against triolein, a l [...]
Irx5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034184Iroquois-class homeodomain protein IRX-5; Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell dif [...]
Irx6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034185Iroquois-class homeodomain protein IRX-6.
Mmp2 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003418772 kDa type IV collagenase; Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, [...]
Ces1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000034189Carboxylesterase 1C; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant; Belongs to the t [...]
Vac14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034190Protein VAC14 homolog; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts as a positive activator of PIKfyve [...]
St3gal2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034197CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2; Responsible for the synthesis of the sequence NeuAc-alpha- 2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups [...]
Cog4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034203Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1.
Nudt21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034204Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation pr [...]
Cenpn protein networkhttps://string-db.org/network/10090.ENSMUSP00000034205Centromere protein N; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segre [...]
Bbs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034206Bardet-Biedl syndrome 2 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is [...]
Mt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034207Metallothionein-4; Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia; Belongs to the metallothionein superf [...]
Mt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034211Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortica [...]
Mt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034214Metallothionein-2; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoid [...]
Mt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034215Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoid [...]
Slc12a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034218Solute carrier family 12 member 3; Electroneutral sodium and chloride ion cotransporter. In kidney distal convoluted tubules, key mediator of sodium and chloride reabsorption (By similarity). Rec [...]
Cntnap4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034225Contactin-associated protein-like 4; Presynaptic protein involved in both dopaminergic synaptic transmission and GABAergic system, thereby participating in the structural maturation of inhibitory [...]
Fam192a protein networkhttps://string-db.org/network/10090.ENSMUSP00000034226PSME3-interacting protein; Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of so [...]
Pllp protein networkhttps://string-db.org/network/10090.ENSMUSP00000034227Plasmolipin; Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are vo [...]
Arl2bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000034228ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effec [...]
Cx3cl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034230Processed fractalkine; Acts as a ligand for both CX3CR1 and integrins. Binds to CX3CR1 and to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-i [...]
Ccl22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034231C-C motif chemokine 22; Chemotactic for activated T-lymphocytes. May play an important role in the collaboration of dendritic cells and B- lymphocytes with T-cells in immune responses.
Ccl17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034232C-C motif chemokine; Belongs to the intercrine beta (chemokine CC) family.
Coq9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034234Ubiquinone biosynthesis protein COQ9, mitochondrial; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for a [...]
Katnb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034239Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of [...]
Kifc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034240Kinesin-like protein KIFC3; Minus-end microtubule-dependent motor protein. Involved in apically targeted transport. Required for zonula adherens maintenance.
Mmp15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034243Matrix metalloproteinase-15; Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A; Belongs to the peptidase M10A family.
Tmem38a protein networkhttps://string-db.org/network/10090.ENSMUSP00000034244Trimeric intracellular cation channel type A; Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions [...]
Usb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034245U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides [...]
Cfap20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034249Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and mor [...]
B3gnt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034260N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3; Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Has activity for type 2 oligosacc [...]
Insl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034261Insulin-like 3 A chain; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity).
Pgls protein networkhttps://string-db.org/network/10090.ENSMUSP000000342646-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
1700018B08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000034265RIKEN cDNA 1700018B08 gene.
Slc27a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034267Long-chain fatty acid transport protein 1; Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an ac [...]
Map1lc3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000034270Microtubule-associated proteins 1A/1B light chain 3B; Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to reg [...]
Mvb12a protein networkhttps://string-db.org/network/10090.ENSMUSP00000034272Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bod [...]
Emc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034277ER membrane protein complex subunit 8; Belongs to the EMC8/EMC9 family.
Gins2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034278DNA replication complex GINS protein PSF2; The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind pref [...]
Gse1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034279Genetic suppressor element 1.
Zdhhc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034280Palmitoyltransferase ZDHHC7; Palmitoyltransferase with broad specificity. Palmitoylates JAM3 (By similarity). Palmitoylates SNAP25 and DLG4/PSD95. Palmitoylates sex steroid hormone receptors, inc [...]
6430548M08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000034281Uncharacterized protein KIAA0513.
Crispld2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034282Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly.
Cotl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034285Coactosin-like protein; Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and a [...]
Klhl36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034287Kelch-like protein 36; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Pik3r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034296Phosphatidylinositol 3-kinase regulatory subunit beta; Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5- bisphosphate) [...]
Hsbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034300Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stres [...]
Mphosph6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034303M-phase phosphoprotein 6; RNA-binding protein that associates with the RNA exosome complex. Involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and plays a role in recruiting [...]
Hsd17b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034304Estradiol 17-beta-dehydrogenase 2; Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha- HSD activity. Uses NADH whil [...]
Bco1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034308Beta,beta-carotene 15,15'-dioxygenase; Symmetrically cleaves beta-carotene into two molecules of retinal using a dioxygenase mechanism; Belongs to the carotenoid oxygenase family.
Lsm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034311U6 snRNA-associated Sm-like protein LSm4; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatal [...]
Ntpcr protein networkhttps://string-db.org/network/10090.ENSMUSP00000034313Cancer-related nucleoside-triphosphatase homolog; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency (By similarity).
Map3k21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034316Mitogen-activated protein kinase kinase kinase 21; Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways (By similarity).
Lpar2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034325Lysophosphatidic acid receptor 2; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of hete [...]
Atp13a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034326Manganese-transporting ATPase 13A1; Mediates manganese transport into the endoplasmic reticulum. The ATPase activity is required for cellular manganese homeostasis (By similarity).
Cdh5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034339Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus con [...]
Cklf protein networkhttps://string-db.org/network/10090.ENSMUSP00000034342Chemokine-like factor; May play an important role in inflammation and regeneration of skeletal muscle.
Cmtm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034343CKLF-like MARVEL transmembrane domain-containing protein 3.
Cmtm2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000034344CKLF-like MARVEL transmembrane domain-containing protein 2A; Belongs to the chemokine-like factor family.
Ces2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000034346Pyrethroid hydrolase Ces2a; Carboxylesterases that catalyzes the hydrolysis of pyrethroids pesticides. Hydrolyzes permethrin faster than cypermethrin.
Nae1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034349NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter l [...]
Rrad protein networkhttps://string-db.org/network/10090.ENSMUSP00000034351GTP-binding protein RAD; May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channe [...]
Ces2e protein networkhttps://string-db.org/network/10090.ENSMUSP00000034355Pyrethroid hydrolase Ces2e; Carboxylesterase that catalyzes the hydrolysis of pyrethroids pesticides. Hydrolyzes trans-permethrin at a rate about 22-fold higher than cis-permethrin. Also hydrolyz [...]
Tradd protein networkhttps://string-db.org/network/10090.ENSMUSP00000034359Tumor necrosis factor receptor type 1-associated DEATH domain protein; Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 med [...]
D230025D16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000034361UPF0183 protein C16orf70 homolog; Belongs to the UPF0183 family.
Hsd11b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034363Corticosteroid 11-beta-dehydrogenase isozyme 2; Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonse [...]
Tsnaxip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034365Translin-associated factor X-interacting protein 1; Possible role in spermatogenesis.
Ctrl protein networkhttps://string-db.org/network/10090.ENSMUSP00000034368Chymotrypsin A CTRA-1; Belongs to the peptidase S1 family.
Psmb10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034369Proteasome subunit beta type-10; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the le [...]
Slc12a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034370Solute carrier family 12 member 4; Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involv [...]
Dpep3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034371Dipeptidase 3; Probable metalloprotease which hydrolyzes cystinyl-bis- glycine. May be involved in meiosis.
Dpep2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034373Dipeptidase 2; Probable metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).
Dus2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034375tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively [...]
Pla2g15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034377Group XV phospholipase A2; Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N-acetylsphingosine and the concomitant release of a lyso-phosph [...]
Slc7a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034378Y+L amino acid transporter 2; Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to [...]
Zfp90 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034382Zinc finger protein 90; Inhibits the transcriptional repressor activity of REST by inhibiting its binding to DNA, thereby derepressing transcription of REST target genes.
Has3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034385Hyaluronan synthase 3; Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most ex [...]
Vps4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000034388Vacuolar protein sorting-associated protein 4A; Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes thei [...]
Nip7 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003439260S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
Tmed6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034393Transmembrane emp24 domain-containing protein 6.
Mtmr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034396Myotubularin-related protein 2; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards pho sphatidylinositol 3-phosphate and phosphatidylinositol 3,5- [...]
Cep57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034398Centrosomal protein of 57 kDa; Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear t [...]
Cyb5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000034400Cytochrome b5 type B; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.
Mre11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000034405Double-strand break repair protein MRE11; Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and me [...]
Gpr83 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034408Probable G-protein coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor.
Izumo1r protein networkhttps://string-db.org/network/10090.ENSMUSP00000034409Sperm-egg fusion protein Juno; Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO [...]
Med17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034411Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Vstm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034413V-set and transmembrane domain-containing protein 5; Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by [...]
Taf1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000034415TATA box-binding protein-associated factor RNA polymerase I subunit D; Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation comple [...]
Adat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034427tRNA-specific adenosine deaminase 1; Specifically deaminates adenosine-37 to inosine in tRNA-Ala. Belongs to the ADAT1 family.
Gabarapl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034428Gamma-aminobutyric acid receptor-associated protein-like 2; Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAR [...]
Tmem231 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034429Transmembrane protein 231; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of tra [...]
Chst5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034430Carbohydrate sulfotransferase 5; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetyl [...]
Tmem170 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034431Transmembrane protein 170A; Acts as a regulator of endoplasmic reticulum (ER) and nuclear envelope (NE) morphogenesis. Affects the ratio between tubular ER and ER sheets by promoting sheet format [...]
Cfdp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034432Craniofacial development protein 1; May play a role during embryogenesis. May modulate tooth organogenesis since alterations of this protein function affect tooth organs size as well as individua [...]
Ctrb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034435Chymotrypsin B chain A; Belongs to the peptidase S1 family.
Wdr59 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034437GATOR complex protein WDR59; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC [...]
Aars protein networkhttps://string-db.org/network/10090.ENSMUSP00000034441Alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor [...]
Cdh15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034443Cadherin-15; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the [...]
Acta1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034453Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Urb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034457URB2 ribosome biogenesis 2 homolog (S. cerevisiae).
Galnt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034458Polypeptide N-acetylgalactosaminyltransferase 2 soluble form; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a ser [...]
Cog2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034460Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function.
Arv1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034463Protein ARV1; Plays a role as a mediator in the endoplasmic reticulum (ER) cholesterol and bile acid homeostasis. Participates in sterol transport out of the ER and distribution into plasma membr [...]
2310022B05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000034464Uncharacterized protein C1orf198 homolog.
2810004N23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000034465Uncharacterized protein C1orf131 homolog.
Gnpat protein networkhttps://string-db.org/network/10090.ENSMUSP00000034466Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family.
Sprtn protein networkhttps://string-db.org/network/10090.ENSMUSP00000034467SprT-like domain-containing protein Spartan; Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated PCNA that enhances RAD18-mediated PCNA ubiquitination and translesion [...]
Egln1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034469Egl nine homolog 1; Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydrox [...]
Vps26b protein networkhttps://string-db.org/network/10090.ENSMUSP00000034470Vacuolar protein sorting-associated protein 26B; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective [...]
Jam3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034472Junctional adhesion molecule C; Junctional adhesion protein that mediates heterotypic cell- cell interactions with its cognate receptor JAM2 to regulate different cellular processes. Plays a role [...]
Spata19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034473Spermatogenesis-associated protein 19, mitochondrial; May have a role in spermiogenesis.
St14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034478Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site (By si [...]
Mmp20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034487Matrix metalloproteinase-20; Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and th [...]
Mmp10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034488Stromelysin-2; Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase; Belongs to the peptidase M10A family.
Mmp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034497Stromelysin-1; Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
Usp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034508Ubiquitin carboxyl-terminal hydrolase 2; Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1 (By similarity). Isoform 1 and isoform 2 possess both ubiqui [...]
Nectin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034510Nectin-1; Involved in cell adhesion and synaptogegesis. Has some neurite outgrowth-promoting activity. Receptor for alphaherpesvirus (HSV-1, HSV-2 and pseudorabies virus) entry into cells. Belong [...]
Trim29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034511Tripartite motif-containing protein 29; Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, [...]
Oaf protein networkhttps://string-db.org/network/10090.ENSMUSP00000034512Out at first protein homolog; Belongs to the OAF family.
Jhy protein networkhttps://string-db.org/network/10090.ENSMUSP00000034521Jhy protein; Required for the normal development of cilia in brain ependymal cells lining the ventricular surfaces.
Clmp protein networkhttps://string-db.org/network/10090.ENSMUSP00000034522CXADR-like membrane protein; May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development [...]
Rexo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034524Oligoribonuclease, mitochondrial; 3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. M [...]
Nxpe2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034527NXPE family member 2.
Cul5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034529Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degra [...]
Kcnj5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034533G protein-activated inward rectifier potassium channel 4; This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow [...]
Ets1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034534Protein C-ets-1; Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival [...]
St3gal4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034537CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4; Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4- GlcNAc-, and NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences [...]
Dcps protein networkhttps://string-db.org/network/10090.ENSMUSP00000034539m7GpppX diphosphatase; Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hyd [...]
Srpr protein networkhttps://string-db.org/network/10090.ENSMUSP00000034541Signal recognition particle receptor subunit alpha; Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targetin [...]
Rpusd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034543Mitochondrial RNA pseudouridine synthase Rpusd4; Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitoc [...]
Acat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034547Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into [...]
Fdx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034552Adrenodoxin, mitochondrial; Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from a [...]
Pou2af1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034554POU domain class 2-associating factor 1; Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, t [...]
Alg9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034561Alpha-1,2-mannosyltransferase ALG9; Catalyzes the transfer of mannose from Dol-P-Man to lipid- linked oligosaccharides.
2310030G06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000034564Uncharacterized protein C11orf52 homolog.
Dixdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034566Dixin; Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.
Dlat protein networkhttps://string-db.org/network/10090.ENSMUSP00000034567Dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and [...]
Pts protein networkhttps://string-db.org/network/10090.ENSMUSP000000345706-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydr [...]
Apoa4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034585Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a [...]
Apoa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034588Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor [...]
Tagln protein networkhttps://string-db.org/network/10090.ENSMUSP00000034590Transgelin; Actin cross-linking/gelling protein.
Bace1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034591Beta-secretase 1; Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, [...]
Dscaml1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034592Down syndrome cell adhesion molecule-like protein 1 homolog; Cell adhesion molecule that plays a role in neuronal self- avoidance. Promotes repulsion between specific neuronal processes of either [...]
Il10ra protein networkhttps://string-db.org/network/10090.ENSMUSP00000034594Interleukin-10 receptor subunit alpha; Cell surface receptor for the cytokine IL10 that participates in IL10-mediated anti-inflammatory functions, limiting excessive tissue disruption caused by i [...]
Tmprss13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034597Transmembrane protease serine 13.
Tmprss4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034599Transmembrane protease serine 4; Probable protease. Seems to be capable of activating ENaC; Belongs to the peptidase S1 family.
Mpzl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034600Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion; Belongs to the myelin P0 protein family.
Cd3d protein networkhttps://string-db.org/network/10090.ENSMUSP00000034602T-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cel [...]
Arcn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034607Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynt [...]
Treh protein networkhttps://string-db.org/network/10090.ENSMUSP00000034609Trehalase; Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose; Belongs to the glycosyl hydrolase 37 family.
Pate4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034610Prostate and testis expressed protein 4; Enhances sperm motility. Binds to calmodulin and inhibits calcium transport into spermatozoa. May modulate the function of nicotinic acetylcholine recepto [...]
Phldb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034611Pleckstrin homology-like domain family B member 1.
Ddx25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034612ATP-dependent RNA helicase DDX25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development.
Pus3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034615tRNA pseudouridine(38/39) synthase; Formation of pseudouridine at position 39 in the anticodon stem and loop of transfer RNAs. Also acts on position 38, but much less efficiently.
Pdzd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034618Na(+)/H(+) exchange regulatory cofactor NHE-RF4; Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation (By similarity). [...]
Pate6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034619Prostate and testis-expressed 6.
Acrv1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034620Acrosomal protein SP-10.
Nlrx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034621NLR family member X1; Participates in antiviral signaling; Belongs to the NLRP family.
Trappc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034623Trafficking protein particle complex subunit 4; May play a role in vesicular transport from endoplasmic reticulum to Golgi. May play a role in dendrite postsynaptic membrane trafficking; Belongs [...]
Fez1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034630Fasciculation and elongation protein zeta-1; May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. May partic [...]
Tmem218 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034632Transmembrane protein 218; May be involved in ciliary biogenesis or function.
Vps11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034644Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pa [...]
Mcam protein networkhttps://string-db.org/network/10090.ENSMUSP00000034650Cell surface glycoprotein MUC18; Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells [...]
Mfrp protein networkhttps://string-db.org/network/10090.ENSMUSP00000034654Membrane frizzled-related protein; May play a role in eye development.
Pin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034689Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated Ser/Thr-Pro (pSer/Thr-Pro) motifs. By ind [...]
Olfm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034692Noelin-2; Involved in transforming growth factor beta (TGF-beta)- induced smooth muscle differentiation (By similarity). TGF-beta induces expression and nuclear translocation of OLFM2 where it bi [...]
Slc44a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034697Choline transporter-like protein 2; Choline transporter; Belongs to the CTL (choline transporter-like) family.
Tmed1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034698Transmembrane emp24 domain-containing protein 1; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorp [...]
Scg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034699Secretogranin-3; Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May [...]
Yipf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034700Protein YIPF2; Belongs to the YIP1 family.
Lysmd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034702LysM and putative peptidoglycan-binding domain-containing protein 2.
Carm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034703Histone-arginine methyltransferase CARM1; Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription [...]
Bcl2l10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034709Bcl-2-like protein 10; Promotes cell survival. Suppresses apoptosis; Belongs to the Bcl-2 family.
Ldlr protein networkhttps://string-db.org/network/10090.ENSMUSP00000034713Low-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand co [...]
Kank2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034717KN motif and ankyrin repeat domain-containing protein 2; Involved in transcription regulation by sequestering in the cytoplasm nuclear receptor coactivators such as NCOA1, NCOA2 and NCOA3 (By sim [...]
Polr2m protein networkhttps://string-db.org/network/10090.ENSMUSP00000034720DNA-directed RNA polymerase II subunit GRINL1A; Isoform 1 appears to be stable component of the Pol II(G) complex form of RNA polymerase II. Pol II synthesizes mRNA precursors and many functional [...]
Aldh1a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034723Retinal dehydrogenase 2; Converts retinaldehyde to retinoic acid. Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal (By similarity). Lacks activity with ben [...]
Lipc protein networkhttps://string-db.org/network/10090.ENSMUSP00000034731Hepatic triacylglycerol lipase; Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL m [...]
Dnaaf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034734Dynein assembly factor 4, axonemal; Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors t [...]
Khdc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034737KH domain-containing protein 3; Required for maintenance of euploidy during cleavage-stage embryogenesis. Ensures proper spindle assembly by regulating the localization of AURKA via RHOA signalin [...]
Rsl24d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034738Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity).
Rnf111 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034739E3 ubiquitin-protein ligase Arkadia; E3 ubiquitin-protein ligase required for mesoderm patterning during embryonic development. Acts as an enhancer of the transcriptional responses of the SMAD2/S [...]
Nedd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034740E3 ubiquitin-protein ligase NEDD4; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin [...]
Ccnb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034742G2/mitotic-specific cyclin-B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition.
Myo1e protein networkhttps://string-db.org/network/10090.ENSMUSP00000034745Unconventional myosin-Ie; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous co [...]
Mns1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034746Meiosis-specific nuclear structural protein 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis.
Fam81a protein networkhttps://string-db.org/network/10090.ENSMUSP00000034749Protein FAM81A; Belongs to the FAM81 family.
Gcnt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034751Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and [...]
Bnip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034754BCL2/adenovirus E1B 19 kDa protein-interacting protein 2; Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins (By similarity).
Anxa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034756Annexin A2; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in he [...]
Ice2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034761Little elongation complex subunit 2; Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
Rp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034763Retinitis pigmentosa 9 protein homolog; Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1.
Rora protein networkhttps://string-db.org/network/10090.ENSMUSP00000034766Nuclear receptor ROR-alpha; Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequenc [...]
Itga11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034774Integrin alpha-11; Integrin alpha-11/beta-1 is a receptor for collagen. Belongs to the integrin alpha chain family.
Fem1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000034775Protein fem-1 homolog B; Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associate [...]
Cln6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034776Ceroid-lipofuscinosis, neuronal 6.
Calml4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034777Calmodulin-like protein 4.
Phip protein networkhttps://string-db.org/network/10090.ENSMUSP00000034787PH-interacting protein; Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an an [...]
Lca5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034791Lebercilin; Involved in intraflagellar protein (IFT) transport in photoreceptor cilia.
Ankk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034792Ankyrin repeat and protein kinase domain-containing protein 1; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Elovl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034796Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endopla [...]
Tent5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000034802Terminal nucleotidyltransferase 5A.
Zw10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034803Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin [...]
Nnmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000034808Nicotinamide N-methyltransferase; Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenob [...]
Cyp19a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034811Aromatase; A cytochrome P450 monooxygenase that catalyzes the conversion of C19 androgens, androst-4-ene-3,17-dione (androstenedione) and testosterone to the C18 estrogens, estrone and estradiol, [...]
Kif23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034815Kinesin-like protein KIF23; Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during th [...]
Paqr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034817Membrane progestin receptor gamma; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(i) mediated pathway. May be involved in oocyte maturation.
Acsbg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034822Long-chain-fatty-acid--CoA ligase ACSBG1; Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular [...]
Imp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034827U3 small nucleolar ribonucleoprotein protein IMP3; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processi [...]
Crabp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034830Cellular retinoic acid-binding protein 1; Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.
Nr2e3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034831Photoreceptor-specific nuclear receptor; Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. [...]
Ptpn9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034832Tyrosine-protein phosphatase non-receptor type 9; Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus. Belongs to the [...]
Pkm protein networkhttps://string-db.org/network/10090.ENSMUSP00000034834Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP (By similarity). Stimulates POU5F1-mediated transcri [...]
Celf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034840CUGBP Elav-like family member 6; RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre- mRNA that are subject to tissu [...]
Ireb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034843Iron-responsive element-binding protein 2; RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevuli [...]
1700017B05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000034846Uncharacterized protein C15orf39 homolog.
Psma4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034848Proteasome subunit alpha type-4; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles w [...]
Chrnb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034854Neuronal acetylcholine receptor subunit beta-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-cond [...]
Mpi protein networkhttps://string-db.org/network/10090.ENSMUSP00000034856Mannose-6-phosphate isomerase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
Fbxo22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034859F-box only protein 22; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome- dependent degradation of key sarcomeric prot [...]
Cyp1a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034860Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molec [...]
Tmem266 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034862Transmembrane protein 266; Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum. Despite the presence of a voltage-sensor seg [...]
Csk protein networkhttps://string-db.org/network/10090.ENSMUSP00000034863Tyrosine-protein kinase CSK; Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyr [...]
Etfa protein networkhttps://string-db.org/network/10090.ENSMUSP00000034866Electron transfer flavoprotein subunit alpha, mitochondrial; Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehy [...]
Clk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034868Dual specificity protein kinase CLK1; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the sp [...]
Isl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034869Insulin gene enhancer protein ISL-2; Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways.
Cyp11a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034874Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of mo [...]
Tspan3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034876Tetraspanin-3; Regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair.
Tmem30a protein networkhttps://string-db.org/network/10090.ENSMUSP00000034878Cell cycle control protein 50A; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inne [...]
Hmg20a protein networkhttps://string-db.org/network/10090.ENSMUSP00000034879High mobility group protein 20A; Plays a role in neuronal differentiation as chromatin- associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer [...]
Cox7a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034881Cytochrome c oxidase subunit 7A2, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The r [...]
Stoml1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034883Stomatin-like protein 1; May play a role in cholesterol transfer to late endosomes (By similarity). May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit prot [...]
Hcn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034889Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for [...]
Mto1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034896Protein MTO1 homolog, mitochondrial; Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. Belongs to the MnmG family.
Ooep protein networkhttps://string-db.org/network/10090.ENSMUSP00000034900Oocyte-expressed protein homolog; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.
Gsta2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034902Glutathione S-transferase A2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Gsta4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034903Glutathione S-transferase A4; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Elovl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034904Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endopla [...]
Gclc protein networkhttps://string-db.org/network/10090.ENSMUSP00000034905Glutamate--cysteine ligase catalytic subunit; Belongs to the glutamate--cysteine ligase type 3 family.
Mlip protein networkhttps://string-db.org/network/10090.ENSMUSP00000034910Muscular LMNA-interacting protein; Required for precocious cardiac adaptation to stress through integrated regulation of the AKT/mTOR pathways and FOXO1. Regulates cardiac homeostasis and plays a [...]
Tinag protein networkhttps://string-db.org/network/10090.ENSMUSP00000034911Tubulo-interstitial nephritis antigen; Belongs to the peptidase C1 family.
Rasgrf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034912Ras-specific guanine nucleotide-releasing factor 1; Promotes the exchange of Ras-bound GDP by GTP.
Mcrip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034913Mapk-regulated corepressor-interacting protein 1; The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds [...]
Ctsh protein networkhttps://string-db.org/network/10090.ENSMUSP00000034915Cathepsin H heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family.
Map2k5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034920Dual specificity mitogen-activated protein kinase kinase 5; Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to p [...]
Zic1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034927Zinc finger protein ZIC 1; Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cor [...]
Lactb protein networkhttps://string-db.org/network/10090.ENSMUSP00000034929Serine beta-lactamase-like protein LACTB, mitochondrial; Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism (By similarity). Acts by decreasing protein level [...]
Aph1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000034934Gamma-secretase subunit APH-1B; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and [...]
Plscr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034941Phospholipid scramblase 4; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry [...]
Dapk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034944Death-associated protein kinase 2; Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Capa [...]
Ciao2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000034945Cytosolic iron-sulfur assembly component 2A; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster i [...]
Snx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034946Sorting nexin-1; Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphat [...]
Ppib protein networkhttps://string-db.org/network/10090.ENSMUSP00000034947Peptidyl-prolyl cis-trans isomerase B; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the [...]
Csnk1g1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034949Casein kinase I isoform gamma-1; Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It c [...]
Spg21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034955Maspardin; May play a role as a negative regulatory factor in CD4- dependent T-cell activation.
Dpp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034960Dipeptidyl peptidase 8; Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2.
Igdcc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034961Immunoglobulin superfamily DCC subclass member 3; Belongs to the immunoglobulin superfamily. DCC family.
Snapc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034965snRNA-activating protein complex subunit 5; Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence elem [...]
Rpl4 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003496660S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.
Lctl protein networkhttps://string-db.org/network/10090.ENSMUSP00000034969Lactase-like protein; Plays a role in formation of the lens suture in the eye, which is important for normal optical properties of the lens. Belongs to the glycosyl hydrolase 1 family. Klotho sub [...]
Smad3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034973Mothers against decapentaplegic homolog 3; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth fac [...]
Xrn1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000349815'-3' exoribonuclease 1; Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is [...]
Atp1b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034983Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) io [...]
Rasa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034984Ras GTPase-activating protein 2; Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) and phospholipids.
Ube2cbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000034986E3 ubiquitin-protein ligase E3D; E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degr [...]
Rwdd2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000034988RWD domain-containing protein 2A.
Me1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034989NADP-dependent malic enzyme.
Tbx18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000034991T-box transcription factor TBX18; Acts as transcriptional repressor involved in developmental processes of a variety of tissues and organs, including the heart, the coronary vessels, the ureter, [...]
Nt5e protein networkhttps://string-db.org/network/10090.ENSMUSP000000349925'-nucleotidase; Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.
Cmtm6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035007CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance [...]
Cmtm7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035009CKLF-like MARVEL transmembrane domain-containing protein 7; Belongs to the chemokine-like factor family.
Stt3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000035010Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B; Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined gl [...]
Eomes protein networkhttps://string-db.org/network/10090.ENSMUSP00000035020Eomesodermin homolog; Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesod [...]
Trim42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035026Tripartite motif-containing protein 42; Belongs to the TRIM/RBCC family.
Clstn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035027Calsyntenin-2; May modulate calcium-mediated postsynaptic signals.
Copb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035033Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynth [...]
Mrps22 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003503428S ribosomal protein S22, mitochondrial.
Pik3cb protein networkhttps://string-db.org/network/10090.ENSMUSP00000035037Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4 [...]
Armc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035043Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasom [...]
Mras protein networkhttps://string-db.org/network/10090.ENSMUSP00000035045Ras-related protein M-Ras; Serves as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Activates the MAP kinase pathway (By similarity).
Cldn18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035048Claudin-18; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
Nme6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035053Nucleoside diphosphate kinase 6; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism [...]
Map4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035055Microtubule-associated protein 4; Non-neuronal microtubule-associated protein. Promotes microtubule assembly.
Cspg5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035058Chondroitin sulfate proteoglycan 5; May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.
Ngp protein networkhttps://string-db.org/network/10090.ENSMUSP00000035061Neutrophilic granule protein; Acts as an inhibitor of cathepsin B (CTSB) activity. Plays a role as a negative regulator of tumor vascular development, cell invasion and metastasis.
Ptgs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035065Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, suc [...]
Nradd protein networkhttps://string-db.org/network/10090.ENSMUSP00000035069Death domain-containing membrane protein NRADD; Modulates NTRK1 signaling. Can activate several intracellular signaling pathways, leading to activation of JUN. Promotes apoptosis. Promotes transl [...]
Tdgf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035075Teratocarcinoma-derived growth factor; GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated Tdgf1 acts as a Nodal coreceptor in cis. Shedding of Tdgf1 by Tmem8a modulat [...]
Lrrc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035076Leucine-rich repeat-containing protein 2.
Ltf protein networkhttps://string-db.org/network/10090.ENSMUSP00000035077Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferri [...]
Lrrfip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035078Leucine-rich repeat flightless-interacting protein 2; May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin. Positively regul [...]
Mlh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035079DNA mismatch repair protein Mlh1; Heterodimerizes with Pms2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (Msh2-M [...]
Stac protein networkhttps://string-db.org/network/10090.ENSMUSP00000035083SH3 and cysteine-rich domain-containing protein; Promotes expression of the ion channel CACNA1H at the cell membrane, and thereby contributes to the regulation of channel activity. Plays a minor [...]
Fbxl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035090F-box/LRR-repeat protein 2; Calcium-activated substrate recognition component of the SCF (SKP1-cullin-F-box protein) E3 ubiquitin-protein ligase complex, SCF(FBXL2), which mediates the ubiquitina [...]
Myd88 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035092Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2 [...]
Exog protein networkhttps://string-db.org/network/10090.ENSMUSP00000035094Nuclease EXOG, mitochondrial; Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity.
Gorasp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035099Golgi reassembly-stacking protein 1; Plays an important role in assembly and membrane stacking of the Golgi cisternae, and in the reassembly of Golgi stacks after breakdown during mitosis. Key st [...]
Ttc21a protein networkhttps://string-db.org/network/10090.ENSMUSP00000035100Tetratricopeptide repeat protein 21A; Intraflagellar transport (IFT)-associated protein required for spermatogenesis. Required for sperm flagellar formation and intraflagellar transport. Belongs [...]
Rpsa protein networkhttps://string-db.org/network/10090.ENSMUSP0000003510540S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the [...]
Slc25a38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035106Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step [...]
Hhatl protein networkhttps://string-db.org/network/10090.ENSMUSP00000035110Protein-cysteine N-palmitoyltransferase HHAT-like protein; Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN.
Nktr protein networkhttps://string-db.org/network/10090.ENSMUSP00000035112NK-tumor recognition protein; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Component of a putative [...]
Ss18l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035113SS18-like protein 2; Belongs to the SS18 family.
Vipr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035115Vasoactive intestinal polypeptide receptor 1; This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase; Belongs to the G-protein coupled [...]
Pccb protein networkhttps://string-db.org/network/10090.ENSMUSP00000035116Propionyl-CoA carboxylase beta chain, mitochondrial; This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of od [...]
Amotl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035121Angiomotin-like protein 2; Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-c [...]
Ephb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035129Ephrin type-B receptor 1; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling [...]
Slco2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035148Solute carrier organic anion transporter family member 2A1; May mediate the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the cleara [...]
1110059G10Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000035154Uncharacterized protein KIAA1143 homolog.
Rab6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000035155Ras-related protein Rab-6B; Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells (By similarity); Belongs [...]
Srprb protein networkhttps://string-db.org/network/10090.ENSMUSP00000035157Signal recognition particle receptor subunit beta; Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting [...]
Trf protein networkhttps://string-db.org/network/10090.ENSMUSP00000035158Serotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transp [...]
1300017J02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000035163Inhibitor of carbonic anhydrase; Inhibitor for carbonic anhydrase 2 (CA2). Does not bind iron ions.
Topbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035164DNA topoisomerase 2-binding protein 1; Required for DNA replication (By similarity). Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA brea [...]
Uba5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035166Ubiquitin-like modifier-activating enzyme 5; E1-like enzyme which activates UFM1 and SUMO2. Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
Nphp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035167Nephrocystin-3; Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt s [...]
Dnajc13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035170DnaJ heat shock protein family (Hsp40) member C13.
Mrpl3 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003517739S ribosomal protein L3, mitochondrial; Belongs to the universal ribosomal protein uL3 family.
Nudt16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035179U8 snoRNA-decapping enzyme; RNA-binding and decapping enzyme that catalyzes the cleavage of the cap structure of snoRNAs and mRNAs in a metal-dependent manner. Part of the U8 snoRNP complex that [...]
Nudt16l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035180Nudix (nucleoside diphosphate-linked moiety X)-type motif 16-like 2.
Aste1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035181Protein asteroid homolog 1; Possible role in EGF receptor signaling; Belongs to the asteroid family.
Mapkapk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035194MAP kinase-activated protein kinase 3; Stress-activated serine/threonine-protein kinase involved in cytokines production, endocytosis, cell migration, chromatin remodeling and transcriptional reg [...]
Hemk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035196MTRF1L release factor glutamine methyltransferase; N5-glutamine methyltransferase responsible for the methylation of the glutamine residue in the universally conserved GGQ motif of the mitochondr [...]
Mon1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000035202Vacuolar fusion protein MON1 homolog A; Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes. Acts in concert with C [...]
Mst1r protein networkhttps://string-db.org/network/10090.ENSMUSP00000035203Macrophage-stimulating protein receptor alpha chain; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many ph [...]
Bsn protein networkhttps://string-db.org/network/10090.ENSMUSP00000035208Protein bassoon; Scaffold protein of the presynaptic cytomatrix at the active zone (CAZ) which is the place in the synapse where neurotransmitter is released. After synthesis, participates in the [...]
Mst1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035211Hepatocyte growth factor-like protein alpha chain.
Ip6k1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035214Inositol hexakisphosphate kinase 1; Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.
Uba7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035216Ubiquitin-like modifier-activating enzyme 7.
Nckipsd protein networkhttps://string-db.org/network/10090.ENSMUSP00000035218NCK-interacting protein with SH3 domain; Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1) (By similarity). Induces microspike formation, in vi [...]
Prkar2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000035220cAMP-dependent protein kinase type II-alpha regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate mem [...]
Slc25a20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035222Mitochondrial carnitine/acylcarnitine carrier protein; Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial m [...]
Nicn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035227Nicolin-1.
Amt protein networkhttps://string-db.org/network/10090.ENSMUSP00000035230Aminomethyltransferase, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
1700102P08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000035234Uncharacterized protein C3orf62 homolog.
Usp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035237Ubiquitin carboxyl-terminal hydrolase 4; Deubiquitinating enzyme that removes conjugated ubiquitin from target proteins. Deubiquitinates PDPK1. Deubiquitinates TRIM21. Deubiquitinates receptor AD [...]
Thap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035240THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1.
Dhx29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035244ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher [...]
Cinp protein networkhttps://string-db.org/network/10090.ENSMUSP00000035245Cyclin-dependent kinase 2-interacting protein; Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 [...]
Abcg8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035246ATP-binding cassette sub-family G member 8; ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role [...]
Alox12b protein networkhttps://string-db.org/network/10090.ENSMUSP00000035250Arachidonate 12-lipoxygenase, 12R-type; Catalyzes the regio and stereo-specific incorporation of a single molecule of dioxygen into free and esterified polyunsaturated fatty acids generating lipi [...]
Slc30a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035257Zinc transporter 8; Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin ma [...]
Pomt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035260Protein O-mannosyl-transferase 2; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, express [...]
D1Pas1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035261Putative ATP-dependent RNA helicase Pl10; Putative ATP-dependent RNA helicase. Possible role in a key step of the spermatogenic process; Belongs to the DEAD box helicase family. DDX3/DED1 subfami [...]
Prss35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035271Inactive serine protease 35; Belongs to the peptidase S1 family.
Ptov1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035281Prostate tumor-overexpressed gene 1 protein homolog; May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation (By similarity).
Polr3g protein networkhttps://string-db.org/network/10090.ENSMUSP00000035289DNA-directed RNA polymerase III subunit RPC7; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripher [...]
Tfb1m protein networkhttps://string-db.org/network/10090.ENSMUSP00000035291Dimethyladenosine transferase 1, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also require [...]
Ntmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035303N-terminal Xaa-Pro-Lys N-methyltransferase 1, N-terminally processed; Distributive alpha-N-methyltransferase that methylates the N- terminus of target proteins containing the N-terminal motif [Al [...]
Crebl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035304cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cel [...]
Fancd2os protein networkhttps://string-db.org/network/10090.ENSMUSP00000035316FANCD2 opposite strand protein.
Ucn protein networkhttps://string-db.org/network/10090.ENSMUSP00000035321Urocortin; Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) (By similarity). Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta (By similarity). P [...]
Ndufaf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035325Arginine-hydroxylase NDUFAF5, mitochondrial; Arginine hydroxylase involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I, MT- ND1) at early stages. Acts by me [...]
Hif1an protein networkhttps://string-db.org/network/10090.ENSMUSP00000035326Hypoxia-inducible factor 1-alpha inhibitor; Hydroxylates HIF-1 alpha at 'Asn-799' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the [...]
Uba6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035328Ubiquitin-like modifier-activating enzyme 6; Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine [...]
Mab21l4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035332Protein mab-21-like 4.
Tdrd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035338Tudor domain-containing protein 6; Tudor domain-containing protein involved in germ cell development, more specifically the formation of chromatoid body (during spermiogenesis), Balbiani body (du [...]
Tedc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035351Tubulin epsilon and delta complex protein 1; Acts as a positive regulator of ciliary hedgehog signaling. Required for centriole stability. May play a role in counteracting perturbation of actin f [...]
Dstyk protein networkhttps://string-db.org/network/10090.ENSMUSP00000035358Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of bo [...]
Dync1li1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035366Cytoplasmic dynein 1 light intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to [...]
4930447C04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000035376Protein SIX6OS1; Meiotic protein that localizes to the central element of the synaptonemal complex and is required for chromosome synapsis during meiotic recombination. Required for the appropria [...]
Ints6l protein networkhttps://string-db.org/network/10090.ENSMUSP00000035379Integrator complex subunit 6-like.
1700003H04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000035388RIKEN cDNA 1700003H04 gene.
Slc25a43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035392Solute carrier family 25 member 43.
Tmem184a protein networkhttps://string-db.org/network/10090.ENSMUSP00000035399Transmembrane protein 184A; Acts as a heparin receptor in vascular cells (By similarity). May be involved in vesicle transport in exocrine cells and Sertoli cells. Belongs to the TMEM184 family.
Nckap1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000035400Nck-associated protein 1-like; Essential hematopoietic-specific regulator of the actin cytoskeleton. Controls lymphocyte development, activation, proliferation and homeostasis, erythrocyte membra [...]
Plvap protein networkhttps://string-db.org/network/10090.ENSMUSP00000035404Plasmalemma vesicle-associated protein; Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the forma [...]
Atxn2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000035415Ataxin-2-like protein; Involved in the regulation of stress granule and P-body formation.
Pklr protein networkhttps://string-db.org/network/10090.ENSMUSP00000035417Pyruvate kinase PKLR; Plays a key role in glycolysis.
Hoxb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035423Homeobox protein Hox-B5; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Fxyd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035429Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
Btbd16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035433BTB/POZ domain-containing protein 16.
Tmem127 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035434Transmembrane protein 127; Controls cell proliferation acting as a negative regulator of TOR signaling pathway mediated by mTORC1. May act as a tumor suppressor; Belongs to the TMEM127 family.
Cpa6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035435Carboxypeptidase A6; May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensi [...]
Zbed4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035437Zinc finger BED domain-containing protein 4.
Plekhs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035440Pleckstrin homology domain-containing family S member 1.
Lgr6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035444Leucine-rich repeat-containing G-protein coupled receptor 6; Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epi [...]
Nfkbil1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035452NF-kappa-B inhibitor-like protein 1; Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathwa [...]
Abca6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035458ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis.
Ntng2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035468Netrin-G2; Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites.
Gjd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035472Gap junction delta-4 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a [...]
Bank1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035484B-cell scaffold protein with ankyrin repeats; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and [...]
Ccs protein networkhttps://string-db.org/network/10090.ENSMUSP00000035486Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1).
Fmod protein networkhttps://string-db.org/network/10090.ENSMUSP00000035489Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
Kif15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035490Kinesin-like protein KIF15; Plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KLP2 s [...]
Fntb protein networkhttps://string-db.org/network/10090.ENSMUSP00000035498Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth p [...]
Arid4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000035512AT-rich interactive domain-containing protein 4A; DNA-binding protein which modulates activity of several transcription factors including RB1 (retinoblastoma-associated protein) and AR (androgen [...]
4921524L21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000035514RIKEN cDNA 4921524L21 gene.
Pdcd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035515Programmed cell death protein 7; Promotes apoptosis when overexpressed.
Ostm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035516Osteopetrosis-associated transmembrane protein 1; Required for osteoclast and melanocyte maturation and function.
1700003F12Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000035523RIKEN cDNA 1700003F12 gene.
Hirip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035535HIRA-interacting protein 3; May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones.
Spib protein networkhttps://string-db.org/network/10090.ENSMUSP00000035539Transcription factor Spi-B; Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes [...]
Pnmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000035549Phenylethanolamine N-methyltransferase; Converts noradrenaline to adrenaline; Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.
Avp protein networkhttps://string-db.org/network/10090.ENSMUSP00000035551Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin; Belongs to the vasopressin/oxytocin family.
Wdr25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035553WD repeat-containing protein 25.
Slfn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035562Schlafen family member 2.
Flvcr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035569Feline leukemia virus subgroup C receptor-related protein 2; Acts as an importer of heme. Also acts as a transporter for a calcium-chelator complex, important for growth and calcium metabolism (B [...]
Lgals3bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000035579Galectin-3-binding protein; Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells (By similarity).
Ikzf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035583Zinc finger protein Pegasus; DNA-binding protein that binds to the 5'GNNTGTNG-3' core sequence. Transcriptional repressor (By similarity).
Pdia2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035584Protein disulfide-isomerase A2; Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as [...]
Oas3 protein networkhttps://string-db.org/network/10090.ENSMUSP000000355882'-5'-oligoadenylate synthase 3; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in ot [...]
Sec23ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000035610SEC23-interacting protein; Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate [...]
Tpst1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035614Protein-tyrosine sulfotransferase 1; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the pr [...]
Slc24a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035616Solute carrier family 24 (Sodium/potassium/calcium exchanger), member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
Gjb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035630Gap junction beta-6 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a [...]
5530400C23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000035635RIKEN cDNA 5530400C23 gene.
Ppp1r14a protein networkhttps://string-db.org/network/10090.ENSMUSP00000035642Protein phosphatase 1 regulatory subunit 14A; Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylatio [...]
Gcfc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035644GC-rich sequence DNA-binding factor 2; Factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calc [...]
Clvs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035649Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity).
Glis1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035650Zinc finger protein GLIS1; Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5'-GACCACCCAC-3'. By controlling the expression of genes involved in cell diffe [...]
Qsox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035658Sulfhydryl oxidase 1; Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond fo [...]
Tdp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035660Tyrosyl-DNA phosphodiesterase 2; DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phospha [...]
Arap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035662Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3; Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase- activating protein that modulates actin cytoskeleton remodel [...]
Capsl protein networkhttps://string-db.org/network/10090.ENSMUSP00000035663Calcyphosin-like protein.
Ptcra protein networkhttps://string-db.org/network/10090.ENSMUSP00000035683Pre T-cell antigen receptor alpha; The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development. Isoform 1 acts to retain most TCRB intracellul [...]
H2-M3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035687Histocompatibility 2, M region locus 3; Belongs to the MHC class I family.
Ptchd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035709Patched domain-containing protein 3; May play a role in sperm development or sperm function.
Rgl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035726Ral guanine nucleotide dissociation stimulator-like 3; Guanine nucleotide exchange factor (GEF) for Ral-A. Potential effector of GTPase HRas and Ras-related protein M-Ras. Negatively regulates El [...]
Mfsd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035727Major facilitator superfamily domain-containing protein 9.
Cntnap5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000035732Contactin-associated protein like 5-1; May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercel [...]
Pglyrp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035737Peptidoglycan recognition protein 3; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram- [...]
Pygb protein networkhttps://string-db.org/network/10090.ENSMUSP00000035743Glycogen phosphorylase, brain form; Glycogen phosphorylase that regulates glycogen mobilization. Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different [...]
Foxj3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035746Forkhead box protein J3; Transcriptional activator of MEF2C involved in the regulation of adult muscle fiber type identity and skeletal muscle regeneration.
Zic5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035754Zinc finger protein ZIC 5; Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA. Belongs to the GLI C2H2-type zinc-finger prot [...]
Spef2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035762Sperm flagellar protein 2; Required for correct axoneme development in spermatozoa. Important for normal development of the manchette and sperm head morphology. Essential for male fertility. Play [...]
Ttc22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035773Tetratricopeptide repeat protein 22.
Cd53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035781Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells.
Angptl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035784Angiopoietin-related protein 6; May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial [...]
Snx25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035785Sorting nexin-25; May be involved in several stages of intracellular trafficking; Belongs to the sorting nexin family.
Smap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035800Stromal membrane-associated protein 2; GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in clathrin-dependent retrograde transport from early endoso [...]
Col16a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035802Collagen alpha-1(XVI) chain; Involved in mediating cell attachment and inducing integrin- mediated cellular reactions, such as cell spreading and alterations in cell morphology.
Marc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035804Mitochondrial amidoxime-reducing component 1; Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycle [...]
Pknox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035806Homeobox protein PKNOX2.
Ubd protein networkhttps://string-db.org/network/10090.ENSMUSP00000035808Ubiquitin D; Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome, in a NUB1-dependent manner. Prob [...]
Sec24d protein networkhttps://string-db.org/network/10090.ENSMUSP00000035823Sec24-related gene family, member D (S. cerevisiae).
Wfdc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035824WAP four-disulfide core domain 5.
Haus1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035826HAUS augmin-like complex subunit 1; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Akap12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035829A-kinase anchor protein 12; Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC).
Nploc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035851Nuclear protein localization protein 4 homolog; The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER [...]
Crygn protein networkhttps://string-db.org/network/10090.ENSMUSP00000035860Gamma-crystallin N; Crystallins are the dominant structural components of the vertebrate eye lens (Probable). Plays also an important role for integrity and function of auditory nuclei. Belongs t [...]
Alg5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035879Dolichyl-phosphate beta-glucosyltransferase.
Cops8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035884COP9 signalosome complex subunit 8; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator [...]
Scamp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035898Secretory carrier-associated membrane protein 5; Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE ma [...]
Bmpr1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000035900Bone morphogenetic protein receptor type-1A; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phospho [...]
Tfap2e protein networkhttps://string-db.org/network/10090.ENSMUSP00000035902Transcription factor AP-2-epsilon; Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 facto [...]
Chn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035908Beta-chimaerin; GTPase-activating protein for p21-rac.
Fam170a protein networkhttps://string-db.org/network/10090.ENSMUSP00000035910Protein FAM170A; Acts as a nuclear transcription factor that positively regulates the expression of heat shock genes. Binds to heat shock promoter elements (HSE).
Arl4d protein networkhttps://string-db.org/network/10090.ENSMUSP00000035918ADP-ribosylation factor-like protein 4D; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleot [...]
Xrra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035929X-ray radiation resistance-associated protein 1; May be involved in the response of cells to X-ray radiation.
Nol10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035930Nucleolar protein 10.
Fbxo33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035948F-box only protein 33; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradat [...]
Tlk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035961Serine/threonine-protein kinase tousled-like 1; Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle chec [...]
Clcn7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035964H(+)/Cl(-) exchange transporter 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysoso [...]
Vax2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035976Ventral anterior homeobox 2; Transcription factor that may function in dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists including the expression [...]
Arhgef4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035980Rho guanine nucleotide exchange factor 4; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex [...]
Ipo13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035989Importin-13; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the [...]
Gga1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035992ADP-ribosylation factor-binding protein GGA1; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathr [...]
Lrig2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000035999Leucine-rich repeats and immunoglobulin-like domains protein 2.
Tanc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036003Protein TANC1; May be a scaffold component in the postsynaptic density.
Cst13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036005Cystatin-13; May perform a specialized role during sperm development and maturation; Belongs to the cystatin family.
Cdk13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036013Cyclin-dependent kinase 13; Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptid [...]
Pgm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036025Phosphoglucomutase-like protein 5; Component of adherens-type cell-cell and cell-matrix junctions. Lacks phosphoglucomutase activity (By similarity). Belongs to the phosphohexose mutase family.
Clca2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036029Calcium-activated chloride channel regulator 2; Plays a role in modulating chloride current across the plasma membrane in a calcium-dependent manner, and cell adhesion. Involved in basal cell adh [...]
Rhod protein networkhttps://string-db.org/network/10090.ENSMUSP00000036031Rho-related GTP-binding protein RhoD; Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of ac [...]
Ky protein networkhttps://string-db.org/network/10090.ENSMUSP00000036032Kyphoscoliosis peptidase; Probable cytoskeleton-associated protease required for normal muscle growth. Involved in function, maturation and stabilization of the neuromuscular junction. May act by [...]
Foxn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036035Forkhead box protein N3; Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints) (By similarity).
Tob1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036039Protein Tob1; Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Mediates CPEB3-accelerated mRNA deadenylation by binding to CP [...]
Apob protein networkhttps://string-db.org/network/10090.ENSMUSP00000036044Apolipoprotein B-100; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellul [...]
Zfp623 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036049Brain specific protein 5.
Trim46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036053Tripartite motif-containing protein 46; Microtubule-associated protein that is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for [...]
Reep2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036065Receptor expression-enhancing protein 2; Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors (By simila [...]
Il17rd protein networkhttps://string-db.org/network/10090.ENSMUSP00000036076Interleukin-17 receptor D; Feedback inhibitor of fibroblast growth factor mediated Ras- MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nu [...]
Nbas protein networkhttps://string-db.org/network/10090.ENSMUSP00000036082Neuroblastoma-amplified sequence.
Ammecr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036085AMME syndrome candidate gene 1 protein homolog.
Gnaz protein networkhttps://string-db.org/network/10090.ENSMUSP00000036087Guanine nucleotide-binding protein G(z) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Gm8909 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036092Predicted gene 8909; Belongs to the MHC class I family.
Ipo9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036093Importin-9; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the [...]
Poln protein networkhttps://string-db.org/network/10090.ENSMUSP00000036110DNA polymerase nu; DNA polymerase with very low fidelity that catalyzes considerable misincorporation by inserting dTTP opposite a G template, and dGTP opposite a T template. Is the least accurat [...]
Mfsd12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036116Major facilitator superfamily domain-containing protein 12.
Primpol protein networkhttps://string-db.org/network/10090.ENSMUSP00000036119DNA-directed primase/polymerase protein; DNA primase and DNA polymerase required to tolerate replication-stalling lesions by bypassing them. Required to facilitate mitochondrial and nuclear repli [...]
Parp11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036127Protein mono-ADP-ribosyltransferase PARP11; Mono-ADP-ribosyltransferase that mediates mono-ADP- ribosylation of target proteins (By similarity). Plays a role in nuclear envelope stability and nuc [...]
Omt2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000036132Oocyte maturation, beta.
Cmtm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036138CKLF-like MARVEL transmembrane domain-containing protein 5; Belongs to the chemokine-like factor family.
Acsm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036140Acyl-coenzyme A synthetase ACSM1, mitochondrial; Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain [...]
Amdhd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036141N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway; Be [...]
Mroh2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000036148Maestro heat-like repeat-containing protein family member 2B; May play a role in the process of sperm capacitation.
Afg1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000036149AFG1-like ATPase; Putative mitochondrial ATPase. Plays a role in mitochondrial morphology and mitochondrial protein metabolism. Promotes degradation of excess nuclear-encoded complex IV subunits [...]
Six4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036150Homeobox protein SIX4; Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a DNA sequence on these target genes and is involved in processes like [...]
Ptgdr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036159Prostaglandin D2 receptor 2; Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)- protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mo [...]
Gdpd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036175Glycerophosphodiester phosphodiesterase domain-containing protein 5; Glycerophosphodiester phosphodiesterase that promotes neurite formation and drives spinal motor neuron differentiation. Mediat [...]
Rad9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000036177Cell cycle checkpoint control protein RAD9B.
Myo6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036181Unconventional myosin-VI; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Myosin 6 is a reverse-direction motor protein that [...]
Adra2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000036203Alpha-2A adrenergic receptor; Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins.
Chmp4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000036206Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation [...]
Coq10a protein networkhttps://string-db.org/network/10090.ENSMUSP00000036213Coenzyme Q10A.
Armh4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036220Armadillo-like helical domain-containing protein 4.
St6galnac5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036227Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; Involved in the biosynthesis of ganglioside GD1a from GM1b. It exhibits higher activity with glycolipids than with glycoproteins. Belo [...]
Slc7a13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036228Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner.
Galnt11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036240Polypeptide N-acetylgalactosaminyltransferase 11; Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymm [...]
Hsd3b7 protein networkhttps://string-db.org/network/10090.ENSMUSP000000362453 beta-hydroxysteroid dehydrogenase type 7; The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hy [...]
Krt75 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036246Keratin, type II cytoskeletal 75; Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments in the companion layer of the hair follicle (By similarity [...]
Gorab protein networkhttps://string-db.org/network/10090.ENSMUSP00000036253RAB6-interacting golgin; Belongs to the GORAB family.
Abi3bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000036257ABI gene family, member 3 (NESH)-binding protein.
Skiv2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000036265Superkiller viralicidic activity 2-like (S. cerevisiae).
Vav3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036270Guanine nucleotide exchange factor VAV3; Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By sim [...]
Ints7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036277Integrator complex subunit 7; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The [...]
Aipl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036279Aryl-hydrocarbon-interacting protein-like 1; May be important in protein trafficking and/or protein folding and stabilization.
Smad6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036285Mothers against decapentaplegic homolog 6; Binds to regulatory elements in target promoter regions (By similarity). May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor- [...]
Cct2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036288T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex [...]
Sppl2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000036289Signal peptide peptidase-like 2B; Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and [...]
Slc32a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036299Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles.
Lpp protein networkhttps://string-db.org/network/10090.ENSMUSP00000036304Lipoma-preferred partner homolog; May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated [...]
Cmklr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036316Chemokine-like receptor 1; Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of [...]
Trhr protein networkhttps://string-db.org/network/10090.ENSMUSP00000036320Thyrotropin-releasing hormone receptor; Receptor for thyrotropin-releasing hormone. Activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messen [...]
Crlf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036326Cytokine receptor-like factor 2; Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activat [...]
Adamts20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036330A disintegrin and metalloproteinase with thrombospondin motifs 20; May play a role in tissue-remodeling process occurring in both normal and pathological conditions. May have a protease- independ [...]
Hdhd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036337Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily.
Abca9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036338ATP-binding cassette sub-family A member 9; May play a role in monocyte differentiation and lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family.
Shcbp1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000036347Testicular spindle-associated protein SHCBP1L; Testis-specific spindle-associated factor that plays a role in spermatogenesis. In association with HSPA2, participates in the maintenance of spindl [...]
Pcdhga12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036359Protocadherin gamma subfamily A, 12.
Tspyl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036360Testis-specific Y-encoded-like protein 4; Belongs to the nucleosome assembly protein (NAP) family.
Eme1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036361Crossover junction endonuclease EME1; Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Ty [...]
Ccdc122 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036369Coiled-coil domain-containing protein 122.
Fcrla protein networkhttps://string-db.org/network/10090.ENSMUSP00000036380Fc receptor-like A; May be implicated in B-cell differentiation and lymphomagenesis.
Fam207a protein networkhttps://string-db.org/network/10090.ENSMUSP00000036382Protein FAM207A; Belongs to the FAM207 family.
Rac2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036384Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of ef [...]
Pyroxd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036394Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Probable FAD-dependent oxidoreductase; involved in the cellular oxidative stress response (By similarity). Required for n [...]
1700025G04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000036406Uncharacterized protein C1orf21 homolog.
Prkab2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000364105'-AMP-activated protein kinase subunit beta-2; Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy m [...]
Tbata protein networkhttps://string-db.org/network/10090.ENSMUSP00000036422Protein TBATA; Isoform 1 and isoform 2 may play a role in spermatid differentiation. Isoform 1 and isoform 2 regulate thymus function by modulating stromal cell proliferation via interference wit [...]
Tjp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036438Tight junction protein ZO-3; Tjp1, Tjp2, and Tjp3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, an [...]
Rnf167 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036472E3 ubiquitin-protein ligase RNF167; May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin- conjugating enzymes, such as UBE2E [...]
Strip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036477Striatin-interacting proteins 2; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape (By similarity); Belongs to the STRIP famil [...]
Ice1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036482Little elongation complex subunit 1; Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Sp [...]
Spag4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036484Sperm-associated antigen 4 protein; Involved in spermatogenesis. Required for sperm head formation but not required to establish and maintain general polarity of the sperm head. Required for anch [...]
Ctnnal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036487Alpha-catulin; May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).
Mtg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036491Mitochondrial ribosome-associated GTPase 1; Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity (By similarity). Displays mitochondrial GTPase acti [...]
Ccdc182 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036503Coiled-coil domain-containing protein 182.
Fbxw4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036505F-box/WD repeat-containing protein 4; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathw [...]
Ccdc18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036507Coiled-coil domain-containing protein 18.
Zfp472 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036514Zinc finger protein 472.
Esf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036523ESF1 homolog; May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity).
Fam91a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036524Protein FAM91A1; As component of the WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1.
Oosp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036529Oocyte-secreted protein 1; May be involved in cell differentiation. Belongs to the PLAC1 family.
Vmn2r65 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036551Vomeronasal 2, receptor 65.
Ipo4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036555Importin-4; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the [...]
Nol4l protein networkhttps://string-db.org/network/10090.ENSMUSP00000036571Nucleolar protein 4-like.
Wnt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036580Protein Wnt-4; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in the embryonic development of the urogenital tract and the lung. Re [...]
Zfp532 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036582Zinc finger protein 532; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Rxrb protein networkhttps://string-db.org/network/10090.ENSMUSP00000036585Retinoic acid receptor RXR-beta; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retino [...]
Foxh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036591Forkhead box protein H1; Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin si [...]
Lgals2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036598Galectin-2; This protein binds beta-galactoside. Its physiological function is not yet known.
Pdk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036604[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial; Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose [...]
Bloc1s5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036614Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as plat [...]
Idi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036621Isopentenyl-diphosphate delta-isomerase 2; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosp [...]
Gsx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036625GS homeobox 2; During telencephalic development, causes ventralization of pallial progenitors and, depending on the developmental stage, specifies different neuronal fates. At early stages, neces [...]
Sdr9c7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036628Short-chain dehydrogenase/reductase family 9C member 7; Displays weak conversion of all-trans-retinal to all-trans- retinol in the presence of NADH. Has apparently no steroid dehydrogenase activi [...]
Cilp protein networkhttps://string-db.org/network/10090.ENSMUSP00000036631Cartilage intermediate layer protein 1 C1; Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced p [...]
Sgpp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036656Sphingosine-1-phosphate phosphatase 2; Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sp [...]
Dock5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036674Dedicator of cytokinesis protein 5; Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP. Along with DOCK1, mediates [...]
Wdr20rt protein networkhttps://string-db.org/network/10090.ENSMUSP00000036682WD repeat-containing protein 20; Regulator of deubiquitinating complexes. Activates deubiquitinating activity of complexes containing USP12.
Slc41a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036690Solute carrier family 41 member 2; Acts as a plasma-membrane magnesium transporter. Belongs to the SLC41A transporter family.
Eva1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000036695Protein eva-1 homolog C; Binds heparin; Belongs to the EVA1 family.
Gmds protein networkhttps://string-db.org/network/10090.ENSMUSP00000036696GDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydrata [...]
Irgq protein networkhttps://string-db.org/network/10090.ENSMUSP00000036699Immunity-related GTPase family Q protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.
Tcte3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036704Tctex1 domain-containing protein 3.
Gak protein networkhttps://string-db.org/network/10090.ENSMUSP00000036705Cyclin-G-associated kinase; Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Exp [...]
Lars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036710Probable leucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
Atcay protein networkhttps://string-db.org/network/10090.ENSMUSP00000036721Caytaxin; Functions in the development of neural tissues, particularly the postnatal maturation of the cerebellar cortex. May play a role in neurotransmission through regulation of glutaminase/GL [...]
Mrps2 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003672528S ribosomal protein S2, mitochondrial; Required for mitoribosome formation and stability, and mitochondrial translation.
Ascc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036726Activating signal cointegrator 1 complex subunit 3; 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enablin [...]
2010003K11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000036729Uncharacterized protein C11orf86 homolog.
Atf7ip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036731Activating transcription factor 7-interacting protein 2; Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chrom [...]
Gramd1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000036739Protein Aster-C; Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). Contains unique domains for binding [...]
Ninj1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036740Ninjurin-1; Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalen [...]
C1qc protein networkhttps://string-db.org/network/10090.ENSMUSP00000036747Complement C1q subcomponent subunit C; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact wi [...]
Ldlrap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036749Low density lipoprotein receptor adapter protein 1; Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells [...]
Syt15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036755Synaptotagmin-15; May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues; Belongs to the synaptotagmin family.
En2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036761Homeobox protein engrailed-2.
P2ry2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036765P2Y purinoceptor 2; Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylt [...]
Vash2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036768Tubulinyl-Tyr carboxypeptidase 2; Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Acts as an activat [...]
Ctu1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036770Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts [...]
Gdpd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036772Glycerophosphodiester phosphodiesterase domain-containing protein 4; Belongs to the glycerophosphoryl diester phosphodiesterase family.
Slc45a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036774Proton-associated sugar transporter A; Proton-associated glucose transporter in the brain. Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family.
Ccdc15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036784Coiled-coil domain-containing protein 15.
Olig2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036797Oligodendrocyte transcription factor 2; Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. F [...]
Ctsll3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036801Cathepsin L-like 3; Belongs to the peptidase C1 family.
Tmem225 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036816Transmembrane protein 225; Probably inhibits protein phosphatase 1 (PP1) in sperm via binding to catalytic subunit PPP1CC.
Taar3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036817Trace amine-associated receptor 3; Olfactory receptor activated by several primary trace amines, including isoamylamine. Activated by isoamylamine and cyclohexylamine, but not to the correspondin [...]
Entpd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036830Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.
Dgat2l6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036845Diacylglycerol O-acyltransferase 2-like protein 6; Diglyceride acyltransferase that uses fatty acyl-CoA as substrate. Particularly active with oleate as a substrate. Has no wax synthase activity [...]
Mbd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036847Methyl-CpG-binding domain protein 5; Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro) (By similarity).
Oxld1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036860Oxidoreductase-like domain-containing protein 1.
Abcf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036881ATP-binding cassette sub-family F member 1; Required for efficient Cap- and IRES-mediated mRNA translation initiation. Not involved in the ribosome biogenesis (By similarity); Belongs to the ABC [...]
Pkp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036890Plakophilin 2.
H2az1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036907Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machiner [...]
1810046K07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000036912Uncharacterized protein C11orf53 homolog.
Slc25a28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036913Mitoferrin-2; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered i [...]
Vps18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036915Vacuolar protein sorting-associated protein 18 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pa [...]
Slc26a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036916Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Mediates chloride/bicarbonate exchange or chloride-independe [...]
Pik3ip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036921Phosphoinositide-3-kinase-interacting protein 1; Negative regulator of hepatic phosphatidylinositol 3-kinase (PI3K) activity.
Nostrin protein networkhttps://string-db.org/network/10090.ENSMUSP00000036923Nostrin; Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
Ccar2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036924Cell cycle and apoptosis regulator protein 2; Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and [...]
Scd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036936Acyl-CoA desaturase 1; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes th [...]
Themis2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036945Protein THEMIS2; May constitute a control point in macrophage inflammatory response, promoting LPS-induced TLR4-mediated TNF production. Belongs to the themis family.
S100a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036949Protein S100-A10; Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of [...]
Sln protein networkhttps://string-db.org/network/10090.ENSMUSP00000036950Sarcolipin; Reversibly inhibits the activity of ATP2A1 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates calcium re-uptake during muscle relaxation [...]
H1f8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036951Histone H1oo; May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic mat [...]
Foxq1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036952Forkhead box protein Q1; Plays a role in hair follicle differentiation.
Clstn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036962Soluble Alc-alpha; Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances AP [...]
Spata6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036964Spermatogenesis-associated protein 6; Required for formation of the sperm connecting piece during spermiogenesis. Sperm connecting piece is essential for linking the developing flagellum to the h [...]
Igfbpl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036974Insulin-like growth factor-binding protein-like 1; IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs i [...]
Atoh8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036981Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH [...]
Car14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036983Carbonic anhydrase 14; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family.
Trpm8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036991Transient receptor potential cation channel subfamily M member 8; Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold [...]
Opa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036993Dynamin-like 120 kDa protein, mitochondrial; Dynamin-related GTPase that is essential for normal mitochondrial morphology by regulating the equilibrium between mitochondrial fusion and mitochondr [...]
Man1b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000036996Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase; Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single al [...]
Lnpep protein networkhttps://string-db.org/network/10090.ENSMUSP00000036998Leucyl-cystinyl aminopeptidase; Release of an N-terminal amino acid, cleave before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin and angi [...]
Mcph1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037000Microcephalin; Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex (By similarity).
Plekhg6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037004Pleckstrin homology domain-containing family G member 6; Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHO [...]
Hspb8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037007Heat shock protein beta-8; Displays temperature-dependent chaperone activity; Belongs to the small heat shock protein (HSP20) family.
Slco1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037022Solute carrier organic anion transporter family member 1A1; Mediates the Na(+)-independent transport of organic anions such as taurocholate, prostaglandin E2 (PGE2), dehydroepiandrosterone sulfat [...]
Slc38a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037023Putative sodium-coupled neutral amino acid transporter 7; Mediates sodium-dependent transport of amino acids. Substrate preference is ranked l-glutamine > l-histidine > l-serine > l-alanine > l-a [...]
6820408C15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000037024RIKEN cDNA 6820408C15 gene.
Pde4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000037025cAMP-specific 3',5'-cyclic phosphodiesterase 4A; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes; Belongs to the cyclic nucleotide phospho [...]
Tex19.2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037027Testis-expressed protein 19.2; May be required during spermatogenesis, probably by participating in the repression of retrotransposable elements and prevent their mobilization (Probable). With it [...]
Camk1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000037028Calcium/calmodulin-dependent protein kinase type 1D; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, act [...]
Fam53c protein networkhttps://string-db.org/network/10090.ENSMUSP00000037034Protein FAM53C; Belongs to the FAM53 family.
Mindy2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037035Ubiquitin carboxyl-terminal hydrolase MINDY-2; Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins. Can also bind to polyubiquitin chains of different linkage types, incl [...]
Ceacam10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037036Carcinoembryonic antigen-related cell adhesion molecule 10; May interact with other CEACAM proteins on the sperm surface. Belongs to the immunoglobulin superfamily. CEA family.
Tspo protein networkhttps://string-db.org/network/10090.ENSMUSP00000037039Translocator protein; Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Was initially identified as peripheral-type benzodiazepine receptor; [...]
Sstr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037045Somatostatin receptor type 1; Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adeny [...]
Trim41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037055E3 ubiquitin-protein ligase TRIM41; Functions as an E3 ligase that catalyzes the ubiquitin- mediated degradation of protein kinase C. Belongs to the TRIM/RBCC family.
Gmeb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037075Glucocorticoid modulatory element-binding protein 2; Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increas [...]
Lmo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037079Rhombotin-1; May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors.
Fdxacb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037082Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog.
H2-DMa protein networkhttps://string-db.org/network/10090.ENSMUSP00000037088Class II histocompatibility antigen, M alpha chain; Plays a critical role in catalyzing the release of class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class [...]
Lrrn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037096Leucine-rich repeat neuronal protein 1.
Mboat7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037107Lysophospholipid acyltransferase 7; Acyltransferase which contributes to the regulation of free arachidonic acid (AA) in the cell through the remodeling of phospholipids. Mediates the conversion [...]
Lzts3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037109Leucine zipper putative tumor suppressor 3; May be involved in promoting the maturation of dendritic spines, probably via regulating SIPA1L1 levels at the postsynaptic density of synapses; Belong [...]
Cdh6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037113Cadherin-6; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the s [...]
Nexn protein networkhttps://string-db.org/network/10090.ENSMUSP00000037120Nexilin; Involved in regulating cell migration through association with the actin cytoskeleton. Has an essential role in the maintenance of Z line and sarcomere integrity.
Zup1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037121Zinc finger-containing ubiquitin peptidase 1; Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains. Shows only we [...]
Bub1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000037126Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; Essential component of the mitotic checkpoint. Required for normal mitosis progression and tumor suppression. The mitotic checkpoint [...]
Qsox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037128Sulfhydryl oxidase 2; Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond [...]
Tie1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037129Tyrosine-protein kinase receptor Tie-1; Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
Gcsh protein networkhttps://string-db.org/network/10090.ENSMUSP00000037131Glycine cleavage system H protein, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P prote [...]
Disp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037136Protein dispatched homolog 2; Belongs to the dispatched family.
Orai2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037137Protein orai-2; Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1.
Cuzd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037168CUB and zona pellucida-like domain-containing protein 1; CUZD1 antiserum inhibits cell attachment and proliferation of ovarian cancer cells so may be involved in these processes (By similarity). [...]
Zc3h12a protein networkhttps://string-db.org/network/10090.ENSMUSP00000037172Endoribonuclease ZC3H12A; Endoribonuclease involved in various biological functions such as cellular inflammatory response and immune homeostasis, glial differentiation of neuroprogenitor cells, [...]
Tyw1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037173S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1; Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base f [...]
Prex1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037180Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein; Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP f [...]
Kcnj2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037192Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are char [...]
Scai protein networkhttps://string-db.org/network/10090.ENSMUSP00000037194Protein SCAI; Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration thro [...]
Fkbp1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000037206Peptidyl-prolyl cis-trans isomerase FKBP1A; Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of l [...]
Git1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037210ARF GTPase-activating protein GIT1; GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling ves [...]
Arl5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000037214ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP.
Catsper2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037222Cation channel sperm-associated protein 2; Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a [...]
Rnf146 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037224E3 ubiquitin-protein ligase RNF146; E3 ubiquitin-protein ligase that specifically binds poly-ADP- ribosylated (PARsylated) proteins and mediates their ubiquitination and subsequent degradation. M [...]
Zfp292 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037233Zinc finger protein 292; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Rilp protein networkhttps://string-db.org/network/10090.ENSMUSP00000037238Rab-interacting lysosomal protein; Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induce [...]
B4galnt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037239Beta-1,4 N-acetylgalactosaminyltransferase 2; Responsible for synthesis of murine T-lymphocyte CT antigen. Can transfer N-acetylgalactosamine moiety from UDP-GalNAc to the low molecular weight ac [...]
Igsf10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037246Immunoglobulin superfamily member 10; Involved in the control of early migration of neurons expressing gonadotropin-releasing hormone (GNRH neurons). May be involved in the maintenance of osteoch [...]
Dhx8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037251ATP-dependent RNA helicase DHX8; Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
Grm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037255Metabotropic glutamate receptor 1; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G protein [...]
C1ql2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037257Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.
Ugt1a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037258UDP-glucuronosyltransferase 1-2; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
Fmo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037259Dimethylaniline monooxygenase [N-oxide-forming] 1; This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenatio [...]
Fkbpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000037273FK506-binding protein-like; May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.
Ggact protein networkhttps://string-db.org/network/10090.ENSMUSP00000037278Gamma-glutamylaminecyclotransferase; Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes t [...]
H1f6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037304Histone H1t; Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes. Formation of more relaxed chromatin may be required to promote chromatin archite [...]
Gipc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037328PDZ domain-containing protein GIPC2; Belongs to the GIPC family.
Wdr70 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037340WD repeat-containing protein 70; Belongs to the WD repeat GAD-1 family.
Ndufb7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037341NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved [...]
Acaa2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000373483-ketoacyl-CoA thiolase, mitochondrial; In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta- oxidation pathway, an aerobic pro [...]
Lce1f protein networkhttps://string-db.org/network/10090.ENSMUSP00000037349Late cornified envelope 1F.
Upf3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000037354UPF3 regulator of nonsense transcripts homolog A (Yeast).
Rpgr protein networkhttps://string-db.org/network/10090.ENSMUSP00000037358X-linked retinitis pigmentosa GTPase regulator; Could be a guanine-nucleotide releasing factor (By similarity). Plays a role in ciliogenesis (By similarity). Probably regulates cilia formation by [...]
Rsad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037361Radical S-adenosyl methionine domain-containing protein 1, mitochondrial; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyri [...]
Echdc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037371Enoyl-CoA hydratase domain-containing protein 3, mitochondrial; May play a role in fatty acid biosynthesis and insulin sensitivity; Belongs to the enoyl-CoA hydratase/isomerase family.
Fbxo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037377F-box only protein 2; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradatio [...]
Lepr protein networkhttps://string-db.org/network/10090.ENSMUSP00000037385Leptin receptor; Receptor for hormone LEP/leptin (Probable). On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STA [...]
Tbx10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037401T-box transcription factor TBX10; Probable transcriptional regulator involved in developmental processes.
Ttll4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037406Tubulin polyglutamylase TTLL4; Glutamylase which preferentially modifies beta-tubulin and non-tubulin proteins, such as NAP1L1, NAP1L4 and CGAS. Involved in the side-chain initiation step of the [...]
Galp protein networkhttps://string-db.org/network/10090.ENSMUSP00000037408Galanin-like peptide; [Isoform 1]: Hypothalamic neuropeptide which binds to the G- protein-coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological [...]
Cacna1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000037416Voltage-dependent N-type calcium channel subunit alpha-1B; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of c [...]
Phpt1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003741714 kDa phosphohistidine phosphatase; Exhibits phosphohistidine phosphatase activity.
Eva1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000037422Protein eva-1 homolog A; Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis; Belongs to the EVA1 family.
Noxa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037423NADPH oxidase activator 1; Functions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of [...]
Atg2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000037441Autophagy-related protein 2 homolog B; Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion.
Trpm6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037443Transient receptor potential cation channel subfamily M member 6; Essential ion channel and kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and [...]
Ttyh3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037447Protein tweety homolog 3; Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction (By similarity).
Npl protein networkhttps://string-db.org/network/10090.ENSMUSP00000037454N-acetylneuraminate lyase; Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from b [...]
BC034090 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037456cDNA sequence BC034090.
Zfand1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037459AN1-type zinc finger protein 1; Plays a role in the regulation of cytoplasmic stress granules (SGs) turnover. SGs are dynamic and transient cytoplasmic ribonucleoprotein assemblies important for [...]
Wdr93 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037467WD repeat-containing protein 93.
Slc41a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037473Solute carrier family 41 member 3; Belongs to the SLC41A transporter family.
Tmem30b protein networkhttps://string-db.org/network/10090.ENSMUSP00000037476Cell cycle control protein 50B; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inne [...]
Myrfl protein networkhttps://string-db.org/network/10090.ENSMUSP00000037477Myelin regulatory factor-like protein.
Cyp7b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037487Cytochrome P450 7B1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous oxysterols and steroid hormones, including neurosteroids. Mechanistically, uses molecular oxygen inse [...]
Akp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037497Intestinal-type alkaline phosphatase.
Spem1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037500Spermatid maturation protein 1; Required for proper cytoplasm removal during spermatogenesis.
Rep15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037503Rab15 effector protein; Regulates transferrin receptor recycling from the endocytic recycling compartment.
Tiprl protein networkhttps://string-db.org/network/10090.ENSMUSP00000037514TIP41-like protein; May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex do [...]
Sox30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037519Transcription factor SOX-30; Acts as both a transcriptional activator and repressor. Binds to the DNA sequence 5'-ACAAT- 3' and shows a preference for guanine residues surrounding this core motif [...]
Tbc1d21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037525TBC1 domain family member 21; May act as a GTPase-activating protein for Rab family protein(s). May be involved in acrosome formation and cytoskeletal reorganization during spermiogenesis, possib [...]
Colgalt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037532Procollagen galactosyltransferase 2; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of collagen.
Ltbp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037536Latent-transforming growth factor beta-binding protein 4; Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent [...]
Spg11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037543Spatacsin; May play a role in neurite plasticity by maintaining cytoskeleton stability and regulating synaptic vesicle transport.
Fbxo8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037544F-box only protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential).
Letmd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037546LETM1 domain-containing protein 1; Involved in tumorigenesis and may function as a negative regulator of the p53/TP53.
Ces1g protein networkhttps://string-db.org/network/10090.ENSMUSP00000037555Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family.
Mzt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037557Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome.
Slc19a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037561Thiamine transporter 1; High-affinity transporter for the intake of thiamine. Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
Trpc4ap protein networkhttps://string-db.org/network/10090.ENSMUSP00000037574Short transient receptor potential channel 4-associated protein; Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX [...]
Sv2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000037576Synaptic vesicle glycoprotein 2A; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates ves [...]
Tmed10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037583Transmembrane emp24 domain-containing protein 10; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side [...]
Gpr176 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037586G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repre [...]
Cep78 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037596Centrosomal protein of 78 kDa; May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. May play a role in cilium biogenesis.
Snrpd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037597Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, [...]
Stpg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037603Protein STPG3.
Bri3bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000037609BRI3-binding protein; Involved in tumorigenesis and may function by stabilizing p53/TP53.
Fbl protein networkhttps://string-db.org/network/10090.ENSMUSP00000037613rRNA 2'-O-methyltransferase fibrillarin; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzin [...]
Lrfn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037616Leucine-rich repeat and fibronectin type-III domain-containing protein 3; Cell adhesion molecule that mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgr [...]
L3mbtl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037619Lethal(3)malignant brain tumor-like protein 3; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromat [...]
Ssxb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037624Synovial sarcoma, X member B, breakpoint 1.
Trp53inp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037627Tumor protein p53-inducible nuclear protein 2; Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as [...]
Kdm3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000037628Lysine-specific demethylase 3B; Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates fo [...]
Slc16a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037629Monocarboxylate transporter 8; Very active and specific thyroid hormone transporter. Stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidot [...]
Mrps6 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003763128S ribosomal protein S6, mitochondrial; Belongs to the bacterial ribosomal protein bS6 family.
Ehbp1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037656EH domain-binding protein 1-like protein 1; May act as Rab effector protein and play a role in vesicle trafficking (By similarity). Involved in apical-directed transport in polarized epithelial c [...]
Parp14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037657Protein mono-ADP-ribosyltransferase PARP14; ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate residues on target proteins. In contrast to PARP1 and PARP2, it is not able to [...]
Cyp3a11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037665Cytochrome P450 3A11; Catalyzes erythromycin N-demethylation, nifedipine oxidation and testosterone 6 beta-hydroxylation; Belongs to the cytochrome P450 family.
Tfap2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000037699Transcription factor AP-2-delta; Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors [...]
Ascl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037702Achaete-scute homolog 3; Transcriptional repressor. Inhibits myogenesis.
Lpar3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037712Lysophosphatidic acid receptor 3; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G prot [...]
Tgfbi protein networkhttps://string-db.org/network/10090.ENSMUSP00000037719Transforming growth factor-beta-induced protein ig-h3; Plays a role in cell adhesion. May play a role in cell-collagen interactions (By similarity).
Map3k10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037725Mitogen-activated protein kinase kinase kinase 10; Activates the JUN N-terminal pathway.
Golga1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037735Golgin subfamily A member 1; Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking.
Tph1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037752Tryptophan 5-hydroxylase 1; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
AI182371 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037754Expressed sequence AI182371.
1600002K03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000037758Protein FAM174C.
Csf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037762Granulocyte colony-stimulating factor; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 [...]
Ypel5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037764Protein yippee-like 5; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation o [...]
Bmp8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000037779Bone morphogenetic protein 8A; Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation [...]
Gadd45gip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037783Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effe [...]
Cep72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037788Centrosomal protein of 72 kDa; Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes [...]
Ythdf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037808YTH domain-containing family protein 1; Specifically recognizes and binds N6-methyladenosine (m6A)- containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at in [...]
Ubald1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037809UBA-like domain-containing protein 1; Belongs to the UBALD family.
Myo1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000037819Unconventional myosin-Id; Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity). Plays a role in endosomal protein trafficking, and especially in [...]
Ttyh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037821Protein tweety homolog 2; Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation ( [...]
Slc35b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037834Adenosine 3'-phospho 5'-phosphosulfate transporter 1; Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sul [...]
Evpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000037850Envoplakin; Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments.
Plcl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037854Inactive phospholipase C-like protein 1; Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5- bisphosphate and phosphatid [...]
Fermt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037858Fermitin family homolog 3; Plays a central role in cell adhesion in hematopoietic cells (By similarity). Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-m [...]
Rnf39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037860Ring finger protein 39.
Colec10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037867Collectin-10; Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine. Acts as a chemoattractant, probably involved in the regulation of ce [...]
Rasa4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037869Ras GTPase-activating protein 4; Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an a [...]
Tbc1d12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037884TBC1 domain family member 12; RAB11A-binding protein that plays a role in neurite outgrowth.
Sde2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037890Replication stress response regulator SDE2; Involved in both DNA replication and cell cycle control. Unprocessed SDE2 interacts with PCNA via its PIP-box. The interaction with PCNA prevents monou [...]
Dgkb protein networkhttps://string-db.org/network/10090.ENSMUSP00000037900Diacylglycerol kinase beta; Exhibits high phosphorylation activity for long-chain diacylglycerols.
Ntrk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037909NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activ [...]
Dennd4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000037915DENN/MADD domain-containing 4A.
Mpv17l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037929Mpv17-like protein 2; Required for the assembly and stability of the mitochondrial ribosome (By similarity). Is a positive regulator of mitochondrial protein synthesis (By similarity).
Uggt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037930UDP-glucose:glycoprotein glucosyltransferase 1; Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality [...]
Ube2q1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037939Ubiquitin-conjugating enzyme E2 Q1; Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Involved in female fertility and embryo implantation. May be involved in horm [...]
Kcna4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037958Potassium voltage-gated channel subfamily A member 4; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective [...]
Tox protein networkhttps://string-db.org/network/10090.ENSMUSP00000037966Thymocyte selection-associated high mobility group box protein TOX; Transcriptional regulator with a major role in neural stem cell commitment and corticogenesis as well as in lymphoid cell devel [...]
Bmp2k protein networkhttps://string-db.org/network/10090.ENSMUSP00000037970BMP-2-inducible protein kinase; May be involved in osteoblast differentiation.
Zfp91 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037971E3 ubiquitin-protein ligase ZFP91; Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby act [...]
Trim36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037978E3 ubiquitin-protein ligase Trim36; E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cel [...]
Cldnd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037980Claudin domain-containing protein 2.
Hdac3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000037981Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deace [...]
Clba1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038002Uncharacterized protein CLBA1.
Pde9a protein networkhttps://string-db.org/network/10090.ENSMUSP00000038005High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A; Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specif [...]
Osbpl10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038013Oxysterol-binding protein-related protein 10; Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphat [...]
Hey1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038014Hairy/enhancer-of-split related with YRPW motif protein 1; Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Downstream effector of Notch signalin [...]
Frem3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038015FRAS1-related extracellular matrix protein 3; Extracellular matrix protein which may play a role in cell adhesion.
Tm6sf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038017Transmembrane 6 superfamily member 1; May function as sterol isomerase.
Abcc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038041Multidrug resistance-associated protein 7; ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.
2300002M23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000038043Uncharacterized protein C6orf15 homolog.
Lrg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038048Leucine-rich alpha-2-glycoprotein 1.
Gabrb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038051Gamma-aminobutyric acid receptor subunit beta-3; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. [...]
P3h2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038056Prolyl 3-hydroxylase 2; Prolyl 3-hydroxylase that catalyzes the post-translational formation of 3-hydroxyproline on collagens. Contributes to proline 3-hydroxylation of collagen COL4A1 and COL1A1 [...]
Fn3krp protein networkhttps://string-db.org/network/10090.ENSMUSP00000038061Ketosamine-3-kinase; Ketosamine-3-kinase involved in protein deglycation by mediating phosphorylation of ribuloselysine and psicoselysine on glycated proteins, to generate ribuloselysine-3 phosph [...]
Dhcr24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038063Delta(24)-sterol reductase; Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. In addition to its cholesterol-synthesizing activity, can [...]
H2-Ke6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038069Estradiol 17-beta-dehydrogenase 8; NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heterotetramer with [...]
Ccdc92 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038075Coiled-coil domain-containing protein 92.
Klhl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038080Kelch-like 4.
Klc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038091Kinesin light chain 3; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.
Mcpt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038103Mast cell protease 4; Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-|-Ile [...]
Slc12a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038106Solute carrier family 12 member 9; May be an inhibitor of SLC12A1. Seems to correspond to a subunit of a multimeric transport system and thus, additional subunits may be required for its function [...]
Sh3bgr protein networkhttps://string-db.org/network/10090.ENSMUSP00000038110SH3 domain-binding glutamic acid-rich protein; Belongs to the SH3BGR family.
Metrnl protein networkhttps://string-db.org/network/10090.ENSMUSP00000038126Meteorin-like protein; Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following co [...]
Stap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038130Signal-transducing adaptor protein 2; Substrate of protein kinase PTK6 (By similarity). May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 acti [...]
Thoc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038137THO complex subunit 6 homolog; Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically ass [...]
Kdm5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000038138Lysine-specific demethylase 5B; Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27' [...]
Rskr protein networkhttps://string-db.org/network/10090.ENSMUSP00000038139Ribosomal protein S6 kinase-related protein; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Slc9a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038142Sodium/hydrogen exchanger 3; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by th [...]
Hpn protein networkhttps://string-db.org/network/10090.ENSMUSP00000038149Serine protease hepsin non-catalytic chain; Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Play [...]
Itpr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038150Inositol 1,4,5-trisphosphate receptor type 3; Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
Tex43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038152Testis-expressed protein 43.
Necab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038165N-terminal EF-hand calcium-binding protein 1.
Poglut1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038166Protein O-glucosyltransferase 1; Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in [...]
Hrh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038170Histamine H2 receptor; The H2 subclass of histamine receptors mediates gastric acid secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase; Belongs to [...]
Kat6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000038181Histone acetyltransferase KAT6A; Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyl [...]
Cenpt protein networkhttps://string-db.org/network/10090.ENSMUSP00000038188Centromere protein T; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segre [...]
9130019O22Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000038195RIKEN cDNA 9130019O22 gene.
Fam13b protein networkhttps://string-db.org/network/10090.ENSMUSP00000038199Protein FAM13B; Belongs to the FAM13 family.
Cerk protein networkhttps://string-db.org/network/10090.ENSMUSP00000038203Ceramide kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8- dihydroceram [...]
Rag2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038204V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles [...]
Tsen2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038211tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the spli [...]
Pip5k1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000038225Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; Catalyzes the phosphorylation of phosphatidylinositol 4- phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) [...]
Kdm2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000038229Lysine-specific demethylase 2B; Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated [...]
Lcat protein networkhttps://string-db.org/network/10090.ENSMUSP00000038232Phosphatidylcholine-sterol acyltransferase; Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts chole [...]
Fam168a protein networkhttps://string-db.org/network/10090.ENSMUSP00000038233Protein FAM168A; In cancer context, protects cells from induced-DNA damage and apoptosis. Acts, at least in part, through PI3K/AKT/NFKB signaling pathway and by preventing POLB degradation. Decre [...]
Gpr12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038245G-protein coupled receptor 12; Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production (By similarity). Promotes neurite outgrowth and blocks myelin inhibition in [...]
Rbm4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000038256RNA-binding protein 4B; Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA.
Noc4l protein networkhttps://string-db.org/network/10090.ENSMUSP00000038263Nucleolar complex protein 4 homolog.
Obscn protein networkhttps://string-db.org/network/10090.ENSMUSP00000038264Obscurin; Structural component of striated muscles which plays a role in myofibrillogenesis. Probably involved in the assembly of myosin into sarcomeric A bands in striated muscle (By similarity) [...]
Klhdc8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000038297Kelch domain-containing protein 8A.
Zfp335 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038298Zinc finger protein 335; Component or associated component of some histone methyltransferase complexes may regulate transcription through recruitment of those complexes on gene promoters. Enhance [...]
Gdf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038301Growth/differentiation factor 7.
Mrps28 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003830528S ribosomal protein S28, mitochondrial; Belongs to the bacterial ribosomal protein bS1 family.
Bdp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038321Transcription factor TFIIIB component B'' homolog; General activator of RNA polymerase III transcription. Requires for transcription from all three types of polymerase III promoters. Requires for [...]
Rabif protein networkhttps://string-db.org/network/10090.ENSMUSP00000038335Guanine nucleotide exchange factor MSS4; Guanine-nucleotide-releasing protein that acts on members of the SEC4/YPT1/RAB subfamily. Stimulates GDP release from both YPT1 and RAB3A, but is less act [...]
Mansc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038346MANSC domain-containing protein 1.
Scamp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038350Secretory carrier-associated membrane protein 2; Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface (By similarity).
Foxj1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038351Forkhead box protein J1; Transcription factor specifically required for the formation of motile cilia. Acts by activating transcription of genes that mediate assembly of motile cilia, such as CFA [...]
Rps29 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003835240S ribosomal protein S29.
Mgat5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038359Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; Catalyzes the addition of N-acetylglucosamine (GlcNAc) in beta 1-6 linkage to the alpha-linked mannose of bianten [...]
Abhd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038361Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone recepto [...]
Scube3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038366Signal peptide, CUB and EGF-like domain-containing protein 3; Binds to TGFBR2 and activates TGFB signaling.
Copg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038368Coatomer subunit gamma-2; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosy [...]
Tmcc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038369Transmembrane and coiled-coil domains protein 2; May be involved in the regulation of the proteolytic processing of the amyloid precursor protein (APP) possibly also implicating APOE.
Kdm1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000038373Lysine-specific histone demethylase 1B; Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Req [...]
Parpbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000038375PCNA-interacting partner; Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologou [...]
Nop14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038382Nucleolar protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity).
Alg14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038387UDP-N-acetylglucosamine transferase subunit ALG14 homolog; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic [...]
Ints8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038418Integrator complex subunit 8; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'- box-dependent processing. The Inte [...]
Snx13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038430Sorting nexin-13; May be involved in several stages of intracellular trafficking. Acts as a GAP for Galphas (By similarity). May play a role in endosome homeostasis; Belongs to the sorting nexin [...]
Sidt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038433SID1 transmembrane family member 1; In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp. Not involved in RNA autophagy, a process in which [...]
Slc38a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038438Putative sodium-coupled neutral amino acid transporter 8; Putative sodium-dependent amino acid/proton antiporter.
Rassf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038444Ras association domain-containing protein 7; Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Follo [...]
Asb16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038450Ankyrin repeat and SOCS box protein 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquit [...]
Ndufc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038463NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved [...]
Stk32a protein networkhttps://string-db.org/network/10090.ENSMUSP00000038471Serine/threonine-protein kinase 32A.
Ccr8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038473C-C chemokine receptor type 8; Receptor for the CCL1/SCY1/TCA-3 chemokine.
AW549877 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038476UPF0600 protein C5orf51 homolog.
Zyg11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000038478Protein zyg-11 homolog A; Probably acts as target recruitment subunit in an E3 ubiquitin ligase complex ZYGA-CUL2-elongin BC.
Ptger2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038483Prostaglandin E2 receptor EP2 subtype; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in i [...]
Ttc13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038484Tetratricopeptide repeat domain 13.
Rangrf protein networkhttps://string-db.org/network/10090.ENSMUSP00000038485Ran guanine nucleotide release factor; May regulate the intracellular trafficking of RAN. Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of [...]
Fam171a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038486Protein FAM171A2; Belongs to the FAM171 family.
Atg12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038489Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like [...]
Disp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038490Protein dispatched homolog 3; Plays a role in neuronal proliferation and differentiation. Plays a role in the accumulation of cellular cholesterol. Involved in intracellular lipid droplet formati [...]
Cplx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038502Complexin-1; Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Organizes the SNAREs into a cross-linked zigza [...]
Jakmip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038504Janus kinase and microtubule-interacting protein 1; Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signali [...]
Polr2j protein networkhttps://string-db.org/network/10090.ENSMUSP00000038505DNA-directed RNA polymerase II subunit RPB11; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA [...]
Fstl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038506Follistatin-related protein 5.
Irs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038514Insulin receptor substrate 2; May mediate the control of various cellular processes by insulin.
Cib2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038527Calcium and integrin-binding family member 2; Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreas [...]
Pdxk protein networkhttps://string-db.org/network/10090.ENSMUSP00000038540Pyridoxal kinase; Required for synthesis of pyridoxal-5-phosphate from vitamin B6.
Pck2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038555Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces [...]
Azgp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038559Zinc-alpha-2-glycoprotein; Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers.
Capza3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038562F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of sub [...]
Dcaf15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038568DDB1- and CUL4-associated factor 15; May be involved in ubiquitination and degradation through a DBB1-CUL4 E3 protein-ubiquitin ligase.
Lrrc17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038569Leucine-rich repeat-containing protein 17; Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors.
Slc7a12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038574Solute carrier family 7 (cationic amino acid transporter, y+ system), member 12.
Brca2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038576Breast cancer type 2 susceptibility protein homolog; Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting as [...]
Rrp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038580U3 small nucleolar RNA-interacting protein 2; Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal [...]
Ccdc32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038589Coiled-coil domain-containing protein 32.
Tcp11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038590T-complex protein 11; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization-promoting peptide (FPP) at the sperm membrane that [...]
Socs5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038591Suppressor of cytokine signaling 5; SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate-recognition component of [...]
Taf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038610TATA-box-binding protein-associated factor 4.
Nek11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038611Serine/threonine-protein kinase Nek11; Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on [...]
Jcad protein networkhttps://string-db.org/network/10090.ENSMUSP00000038613Junctional protein associated with coronary artery disease.
Txlng protein networkhttps://string-db.org/network/10090.ENSMUSP00000038615Gamma-taxilin; May be involved in intracellular vesicle traffic (By similarity). Inhibits ATF4-mediated transcription, possibly by dimerizing with ATF4 to form inactive dimers that cannot bind DN [...]
Plppr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038616Phospholipid phosphatase-related protein type 2.
Cipc protein networkhttps://string-db.org/network/10090.ENSMUSP00000038630CLOCK-interacting pacemaker; Transcriptional repressor which may act as a negative- feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulat [...]
Galnt9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038633Polypeptide N-acetylgalactosaminyltransferase.
Trem1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038636Triggering receptor expressed on myeloid cells 1; Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as inc [...]
Fbxl8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038638F-box/LRR-repeat protein 8; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Iqsec3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038653IQ motif and SEC7 domain-containing protein 3; Acts as a guanine nucleotide exchange factor (GEF) for ARF1. Belongs to the BRAG family.
Prr32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038655Proline-rich protein 32.
Ankrd13c protein networkhttps://string-db.org/network/10090.ENSMUSP00000038662Ankyrin repeat domain-containing protein 13C; Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.
Mettl25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038665Methyltransferase-like protein 25; Putative methyltransferase.
Manea protein networkhttps://string-db.org/network/10090.ENSMUSP00000038671Glycoprotein endo-alpha-1,2-mannosidase.
Lrrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038675Leucine-rich repeat and death domain-containing protein 1.
Fndc3c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038678Fibronectin type III domain containing protein 3C1.
Epg5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038681Ectopic P granules protein 5 homolog; Involved in autophagy. May play a role in a late step of autophagy, such as clearance of autophagosomal cargo. Plays a key role in innate and adaptive immune [...]
Slc39a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038707Solute carrier family 39 (zinc transporter), member 2.
Gm49336 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038716Nucleoporin p58/p45; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Belongs to the NUP58 family.
Trim14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038719Tripartite motif-containing protein 14; Plays a role in the innate immune defense against viruses. Facilitates the type I IFN response by interacting with MAVS at the outer mitochondria membrane [...]
Alkbh3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038721Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; Dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A) (By similarity). Repairs alkylated DNA containi [...]
Pomt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038722Protein O-mannosyl-transferase 1; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, express [...]
Kcnk9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038729Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein.
Qpct protein networkhttps://string-db.org/network/10090.ENSMUSP00000038732Glutaminyl-peptide cyclotransferase; Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N- terminal glutaminyl residue an [...]
Lipt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038739Lipoyltransferase 1, mitochondrial; Catalyzes the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes; Belongs to the LplA f [...]
Pde3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000038749cGMP-inhibited 3',5'-cyclic phosphodiesterase A; Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important ph [...]
Wee2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038754Wee1-like protein kinase 2; Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required [...]
Abhd14b protein networkhttps://string-db.org/network/10090.ENSMUSP00000038755Protein ABHD14B; Has hydrolase activity towards p-nitrophenyl butyrate (in vitro). May activate transcription (By similarity).
Esyt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038757Extended synaptotagmin-3; Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glyceroph [...]
Sik2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038761Serine/threonine-protein kinase SIK2; Phosphorylates 'Ser-789' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activi [...]
Pcca protein networkhttps://string-db.org/network/10090.ENSMUSP00000038763Propionyl-CoA carboxylase alpha chain, mitochondrial; This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of o [...]
Ltn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038775E3 ubiquitin-protein ligase listerin; E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extracti [...]
Nepro protein networkhttps://string-db.org/network/10090.ENSMUSP00000038779Nucleolus and neural progenitor protein; May play a role in cortex development as part of the Notch signaling pathway. Downstream of Notch may repress the expression of proneural genes and inhibi [...]
Tbca protein networkhttps://string-db.org/network/10090.ENSMUSP00000038781Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway; Belongs to the TBCA family.
Enc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038783Ectoderm-neural cortex protein 1; Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down- regulates transcription factor [...]
Mcoln3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038801Mucolipin-3; Nonselective ligand-gated cation channel probably playing a role in the regulation of membrane trafficking events. Acts as Ca(2+)- permeable cation channel with inwardly rectifying a [...]
Ube2r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038813Ubiquitin-conjugating enzyme E2 R2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyub [...]
Fem1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000038816Protein fem-1 homolog C; Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit; Belongs to the fem-1 family.
Spidr protein networkhttps://string-db.org/network/10090.ENSMUSP00000038820DNA repair-scaffolding protein; Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DN [...]
Fam92b protein networkhttps://string-db.org/network/10090.ENSMUSP00000038825Protein FAM92B; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early [...]
Ripk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038833Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by ba [...]
Kazn protein networkhttps://string-db.org/network/10090.ENSMUSP00000038835Kazrin; Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known.
Lyn protein networkhttps://string-db.org/network/10090.ENSMUSP00000038838Tyrosine-protein kinase Lyn; Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune re [...]
Eif3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000038839Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein [...]
Rap2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000038841Ras-related protein Rap-2b; Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of P [...]
Btg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038863Protein BTG1; Anti-proliferative protein; Belongs to the BTG family.
Slx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038871Structure-specific endonuclease subunit SLX4; Regulatory subunit that interacts with and increases the activity of different structure-specific endonucleases. Has several distinct roles in protec [...]
Pclaf protein networkhttps://string-db.org/network/10090.ENSMUSP00000038877PCNA-associated factor; PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interact [...]
Aldh8a1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000388782-aminomuconic semialdehyde dehydrogenase; Catalyzes the NAD-dependent oxidation of 2-aminomuconic semialdehyde of the kynurenine metabolic pathway in L-tryptophan degradation.
Htr5a protein networkhttps://string-db.org/network/10090.ENSMUSP000000388845-hydroxytryptamine receptor 5A; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mit [...]
Kcns1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038901Potassium voltage-gated channel subfamily S member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB [...]
Cspg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038909Chondroitin sulfate proteoglycan 4; Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibi [...]
Kmo protein networkhttps://string-db.org/network/10090.ENSMUSP00000038914Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor an [...]
Rhou protein networkhttps://string-db.org/network/10090.ENSMUSP00000038915Rho-related GTP-binding protein RhoU; Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle [...]
Nipal2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038922NIPA-like protein 2.
Foxred1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038924FAD-dependent oxidoreductase domain-containing protein 1; Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Involved in mid-late stages of [...]
Elane protein networkhttps://string-db.org/network/10090.ENSMUSP00000038925Neutrophil elastase; Medullasin modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis (By similarity). Capabl [...]
Gstp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038931Glutathione S-transferase P 2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Cannot metabolize 1-chloro-2,4-dinitrobenzene; Belongs to [...]
Ctdp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038938RNA polymerase II subunit A C-terminal domain phosphatase; Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase I [...]
Selenow protein networkhttps://string-db.org/network/10090.ENSMUSP00000038943Selenoprotein W; Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency; Belongs to the Se [...]
Prrg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038947Transmembrane gamma-carboxyglutamic acid protein 3.
Cpsf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038958Cleavage and polyadenylation specificity factor subunit 7; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation pr [...]
Gm11273 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038961Cytochrome c oxidase subunit 5B, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The re [...]
Rbm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038964RNA-binding protein 3; Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microR [...]
1110008P14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000038970UPF0184 protein C9orf16 homolog; Belongs to the UPF0184 (EST00098) family.
Mfap4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038971Microfibril-associated glycoprotein 4; Could be involved in calcium-dependent cell adhesion or intercellular interactions. May contribute to the elastic fiber assembly and/or maintenance.
Sdk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038972Protein sidekick-2; Adhesion molecule that promotes lamina-specific synaptic connections in the retina and is specifically required for the formation of neuronal circuits that detect motion. Acts [...]
Tex46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038976Testis-expressed 46.
Naa25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038977N-alpha-acetyltransferase 25, NatB auxiliary subunit; Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-As [...]
Washc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038983WASH complex subunit 2; Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes inhibits WASH nucleation- promoting factor (NPF) activity in recruit [...]
Olfr1353 protein networkhttps://string-db.org/network/10090.ENSMUSP00000038992Olfactory receptor.
Wdr55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039010WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis.
Trim7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039011E3 ubiquitin-protein ligase TRIM7; E3 ubiquitin-protein ligase (By similarity). Mediates 'Lys- 63'-linked polyubiquitination and stabilization of the JUN coactivator RNF187 in response to growth [...]
Hoxa5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039012Homeobox protein Hox-A5; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Rragb protein networkhttps://string-db.org/network/10090.ENSMUSP00000039013Ras-related GTP-binding protein B; Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling casc [...]
Hmx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039018Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core seque [...]
Tsr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039027Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus.
Slc7a6os protein networkhttps://string-db.org/network/10090.ENSMUSP00000039029Probable RNA polymerase II nuclear localization protein SLC7A6OS; Directs RNA polymerase II nuclear import; Belongs to the IWR1/SLC7A6OS family.
Ankrd12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039035Ankyrin repeat domain 12.
Flt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039041Receptor-type tyrosine-protein kinase FLT3; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematop [...]
Cpq protein networkhttps://string-db.org/network/10090.ENSMUSP00000039046Carboxypeptidase Q; Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acid [...]
Kcnt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039058Potassium channel subfamily T member 1; Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride [...]
Igsf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039059Immunoglobulin superfamily member 6.
Ramac protein networkhttps://string-db.org/network/10090.ENSMUSP00000039065RNA guanine-N7 methyltransferase activating subunit; Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-c [...]
Mxd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039071Max dimerization protein 4; Transcriptional repressor. Binds with MAX to form a sequence- specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC [...]
Jph1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039072Junctophilin-1; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. [...]
Zfp446 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039073Zinc finger protein 446.
Mettl27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039080Williams-Beuren syndrome critical region protein 27 isoform alpha.
Vsx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039088Visual system homeobox 1; Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster (By similarity). May regulate the activity of the LCR and the cone [...]
Atpsckmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000039094ATP synthase subunit C lysine N-methyltransferase; Mitochondrial protein-lysine N-methyltransferase that trimethylates ATP synthase subunit C, ATP5MC1 and ATP5MC2. Trimethylation is required for [...]
Cnot3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039098CCR4-NOT transcription complex subunit 3; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA de [...]
Ccr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039107Probable C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently t [...]
Ppp1ca protein networkhttps://string-db.org/network/10090.ENSMUSP00000039109Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate h [...]
Serbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039110Plasminogen activator inhibitor 1 RNA-binding protein; May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nu [...]
Akr1b10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039114Aldo-keto reductase family 1, member B10 (aldose reductase).
Trim62 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039121E3 ubiquitin-protein ligase TRIM62; E3 ubiquitin ligase whose activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2.
Ythdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039133YTH domain-containing protein 1; Regulator of alternative splicing that specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs (By similarity). M6A is a modification present a [...]
Edc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039134Enhancer of mRNA-decapping protein 4; In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of [...]
Arhgap44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039139Rho GTPase-activating protein 44; GTPase-activating protein (GAP) that stimulates the GTPase activity of Rho-type GTPases. Thereby, controls Rho-type GTPases cycling between their active GTP-boun [...]
Ly6g5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000039151Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation.
Hoxa13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039170Homeobox protein Hox-A13; Sequence-specific, AT-rich binding transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the [...]
Hspb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039172Heat shock protein beta-6; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Seems to have versatile functio [...]
Nr0b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039175Nuclear receptor subfamily 0 group B member 2; Transcriptional regulator that acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the n [...]
Relch protein networkhttps://string-db.org/network/10090.ENSMUSP00000039178RAB11-binding protein RELCH; Regulates intracellular cholesterol distribution from recycling endosomes to the trans-Golgi network through interactions with RAB11 and OSBP. Functions in membrane t [...]
Slc25a34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039188Solute carrier family 25 member 34; Belongs to the mitochondrial carrier (TC 2.A.29) family.
Aspdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000039202Putative L-aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
Pvr protein networkhttps://string-db.org/network/10090.ENSMUSP00000039205Poliovirus receptor.
Hace1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039206E3 ubiquitin-protein ligase HACE1; E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cy [...]
Snx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039243Sorting nexin-2; Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphat [...]
Pcdh18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039245Protocadherin 18; Potential calcium-dependent cell-adhesion protein.
Rdh7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039252Retinol dehydrogenase 7; Acts on androgens and retinols, i.e. has steroid 3-alpha- and 17-beta-dehydrogenase and cis/trans-retinol catalytic activities.
Fam189b protein networkhttps://string-db.org/network/10090.ENSMUSP00000039261Protein FAM189B; Belongs to the FAM189 family.
Grifin protein networkhttps://string-db.org/network/10090.ENSMUSP00000039263Grifin.
Fcsk protein networkhttps://string-db.org/network/10090.ENSMUSP00000039271L-fucose kinase; Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides. [Isoform 2]: Has very weak fucokinase activity. Belongs to the GHMP kinas [...]
Smim3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039285Small integral membrane protein 3.
Eif4ebp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039298Eukaryotic translation initiation factor 4E-binding protein 3; Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphoryla [...]
Mios protein networkhttps://string-db.org/network/10090.ENSMUSP00000039301GATOR complex protein MIOS; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 [...]
Gpr63 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039312Probable G-protein coupled receptor 63; Orphan receptor. May play a role in brain function.
Poglut3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039313Protein O-glucosyltransferase 3; Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. [...]
Washc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039322WASH complex subunit 4; Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in [...]
Diaph2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039334Protein diaphanous homolog 2; May be involved in oogenesis; Belongs to the formin homology family. Diaphanous subfamily.
Timm8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000039335Mitochondrial import inner membrane translocase subunit Tim8 B; Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane prote [...]
Tmem247 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039338Transmembrane protein 247.
Mmd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039357Monocyte to macrophage differentiation factor 2; Belongs to the ADIPOR family.
Ppl protein networkhttps://string-db.org/network/10090.ENSMUSP00000039360Periplakin; Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. May act as a localization signal in PKB/AKT-mediated si [...]
Dennd6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000039361Protein DENND6A; Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 [...]
Ptprf protein networkhttps://string-db.org/network/10090.ENSMUSP00000039368Receptor-type tyrosine-protein phosphatase F; Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its a [...]
Exo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039376Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-c [...]
Strc protein networkhttps://string-db.org/network/10090.ENSMUSP00000039378Stereocilin; Essential to the formation of horizontal top connectors between outer hair cell stereocilia.
Bicd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039394Protein bicaudal D homolog 2; Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence [...]
Kirrel2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039395Kin of IRRE-like protein 2; May regulate basal insulin secretion.
U2af1l4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039406Splicing factor U2AF 26 kDa subunit; RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer- dependent splicing by mediating prot [...]
Exoc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039416Exocyst complex component 3; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Vhl protein networkhttps://string-db.org/network/10090.ENSMUSP00000039418Von Hippel-Lindau disease tumor suppressor; Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recrui [...]
Gtf3c3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039420General transcription factor IIIC, polypeptide 3.
Shprh protein networkhttps://string-db.org/network/10090.ENSMUSP00000039422E3 ubiquitin-protein ligase SHPRH; E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of P [...]
Dpyd protein networkhttps://string-db.org/network/10090.ENSMUSP00000039429Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity).
Etfrf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039433Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB [...]
Syne1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039440Nesprin-1; Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. As a component of the LINC [...]
Ptchd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039443Patched domain-containing protein 1; Required for the development and function of the thalamic reticular nucleus (TRN), a part of the thalamus that is critical for thalamocortical transmission, g [...]
Tnn protein networkhttps://string-db.org/network/10090.ENSMUSP00000039452Tenascin-N; Extracellular matrix protein that seems to be a ligand for ITGA8:ITGB1, ITGAV:ITGB1 and ITGA4:ITGB1 (By similarity). Involved in neurite outgrowth and cell migration in hippocampal ex [...]
Fgb protein networkhttps://string-db.org/network/10090.ENSMUSP00000039472Fibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fi [...]
Rcan2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039473Calcipressin-2; Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development; Belongs [...]
Rsbn1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000039482Round spermatid basic protein 1-like.
Ankmy2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039484Ankyrin repeat and MYND domain-containing protein 2; May be involved in the trafficking of signaling proteins to the cilia.
Rnf126 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039486E3 ubiquitin-protein ligase RNF126; E3 ubiquitin-protein ligase that mediates ubiquitination oF target proteins (By similarity). Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys [...]
Arglu1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039493Arginine and glutamate-rich protein 1.
Mis12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039500Protein MIS12 homolog; Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis. Essential for proper kinetochore m [...]
Macrod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039507ADP-ribose glycohydrolase MACROD1; Removes ADP-ribose from asparatate and glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Dea [...]
Brsk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039517Serine/threonine-protein kinase BRSK1; Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, [...]
Ckap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039518Cytoskeleton-associated protein 2; Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53-dependent manner; Belongs to the CKAP2 fa [...]
Rfpl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039519Ret finger protein-like 4A.
Tmem109 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039529Transmembrane protein 109; May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death. Can form voltage-gated calcium and potassium channels in vitro (By s [...]
Nudt15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039537Nucleotide triphosphate diphosphatase NUDT15; May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP, dCTP, their oxidized forms like 8-oxo-dGTP and the prodrug thiopurine d [...]
Tasp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039546Threonine aspartase subunit alpha; Protease involved in KMT2A/MLL1 processing and, consequently, in the correct expression of the early HOXA gene cluster.
Pcif1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039555mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase; Cap-specific adenosine methyltransferase that catalyzes formation of N(6),2'-O-dimethyladenosine cap (m6A(m)) by methylating the adenosine at [...]
Pkn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039566Serine/threonine-protein kinase N2; PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role [...]
Sec22a protein networkhttps://string-db.org/network/10090.ENSMUSP00000039568Vesicle-trafficking protein SEC22a; May be involved in vesicle transport between the ER and the Golgi complex; Belongs to the synaptobrevin family.
Ptpn23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039580Tyrosine-protein phosphatase non-receptor type 23; Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endoso [...]
Serpine1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039586Plasminogen activator inhibitor 1; Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase- type plasminogen activator (PLAU) [...]
Fig4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039598Polyphosphoinositide phosphatase; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). In vitro, hydrolyzes all thr [...]
Ccl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039600C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several c [...]
Mul1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039604Mitochondrial ubiquitin ligase activator of NFKB 1; Exhibits weak E3 ubiquitin-protein ligase activity (By similarity). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzy [...]
Rfc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039621Replication factor C subunit 3; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) [...]
Plekhh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039628Pleckstrin homology domain-containing family H member 2; In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabil [...]
Osbpl11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039632Oxysterol-binding protein-related protein 11; Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage [...]
Tln2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039633Talin-2; As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and [...]
Il25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039641Interleukin 25.
Ccdc27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039642Coiled-coil domain-containing protein 27.
Atp13a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039648Cation-transporting ATPase 13A2; ATPase that plays a role in intracellular cation homeostasis and the maintenance of neuronal integrity. Required for a proper lysosomal and mitochondrial maintena [...]
Nodal protein networkhttps://string-db.org/network/10090.ENSMUSP00000039653Nodal; Essential for mesoderm formation and axial patterning during embryonic development; Belongs to the TGF-beta family.
Nup205 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039656Nucleoporin 205.
Atp1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039657Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium [...]
Fzd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039660Frizzled-8; Receptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-size [...]
Dmgdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000039663Dimethylglycine dehydrogenase, mitochondrial; Catalyzes the demethylation of N,N-dimethylglycine to sarcosine. Also has activity with sarcosine in vitro.
Tab3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039668TGF-beta-activated kinase 1 and MAP3K7-binding protein 3; Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL-1 and TNF signaling pathways. Plays [...]
Unkl protein networkhttps://string-db.org/network/10090.ENSMUSP00000039670Putative E3 ubiquitin-protein ligase UNKL; May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other subst [...]
Gm5771 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039684Predicted gene, EG436523; Belongs to the peptidase S1 family.
Kri1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039688Protein KRI1 homolog; Belongs to the KRI1 family.
Dzip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039689Zinc finger protein DZIP1; May participate in spermatogenesis via its interaction with DAZL. Has a role in primary cilium formation. Belongs to the DZIP C2H2-type zinc-finger protein family.
Drd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039691D(1B) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family.
Ndufa7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039692NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved [...]
Muc5ac protein networkhttps://string-db.org/network/10090.ENSMUSP00000039699Mucin 5, subtypes A and C, tracheobronchial/gastric.
Parp12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039704Protein mono-ADP-ribosyltransferase PARP12; Mono-ADP-ribosyltransferase that mediates mono-ADP- ribosylation of target proteins.
Micall2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039707MICAL-like protein 2; Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin [...]
Pcm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039709Pericentriolar material 1 protein; Required for centrosome assembly and function. Essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2 (By [...]
Atp6v0a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039737V-type proton ATPase 116 kDa subunit a isoform 2; Part of the proton channel of V-ATPases (By similarity). Essential component of the endosomal pH-sensing machinery. May play a role in maintainin [...]
Cylc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039750Cylicin, basic protein of sperm head cytoskeleton 2.
B4galnt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039758N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-lin [...]
Ypel1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039760Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts.
Dbil5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039763Diazepam-binding inhibitor-like 5; May be involved in the energy metabolism of the mature sperm; Belongs to the ACBP family.
Pold1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039776DNA polymerase delta catalytic subunit; As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in [...]
Mrpl23 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003978439S ribosomal protein L23, mitochondrial; Belongs to the universal ribosomal protein uL23 family.
Zfp40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039794Zinc finger protein 40.
Prkar2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000039797cAMP-dependent protein kinase type II-beta regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate memb [...]
Atoh7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039801Protein atonal homolog 7; Transcription factor involved in the differentiation of most retinal ganglion cells, including those constituting the retino- hypothalamic tract.
Cpz protein networkhttps://string-db.org/network/10090.ENSMUSP00000039804Carboxypeptidase Z; Cleaves substrates with C-terminal arginine residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during proh [...]
Gm11992 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039806Uncharacterized protein C7orf57 homolog.
Prss22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039808Brain-specific serine protease 4; Belongs to the peptidase S1 family.
Csgalnact2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039819Chondroitin sulfate N-acetylgalactosaminyltransferase 2; Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of [...]
Sprr2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000039821Small proline-rich protein 2D; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane [...]
Gm4847 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039839Dimethylaniline monooxygenase [N-oxide-forming].
Actr1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000039844Alpha-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome.
Rrp12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039853RRP12-like protein.
Cd209c protein networkhttps://string-db.org/network/10090.ENSMUSP00000039861CD209 antigen-like protein C; Probable pathogen-recognition receptor. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens.
Hils1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039866Spermatid-specific linker histone H1-like protein; DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of sperm [...]
Ctrc protein networkhttps://string-db.org/network/10090.ENSMUSP00000039879Chymotrypsin-C; Has chymotrypsin-type protease activity and hypocalcemic activity; Belongs to the peptidase S1 family. Elastase subfamily.
Pcdhac2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039888Protocadherin alpha subfamily C, 2.
Cep85 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039889Centrosomal protein of 85 kDa; Acts as a negative regulator of NEK2 to maintain the centrosome integrity in interphase. Suppresses centrosome disjunction by inhibiting NEK2 kinase activity; Belon [...]
Arhgef11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039900Rho guanine nucleotide exchange factor (GEF) 11.
H2-M10.6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039908Major histocompatibility complex class Ib M10.8; Belongs to the MHC class I family.
C030006K11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000039910UPF0598 protein C8orf82 homolog; Belongs to the UPF0598 family.
Dcbld2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039915Discoidin, CUB and LCCL domain-containing protein 2.
Usp38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039943Ubiquitin carboxyl-terminal hydrolase 38; Deubiquitinating enzyme exhibiting a preference towards 'Lys- 63'-linked ubiquitin chains; Belongs to the peptidase C19 family.
Pmepa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039950Protein TMEPAI; Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix product [...]
Mrpl54 protein networkhttps://string-db.org/network/10090.ENSMUSP0000003995139S ribosomal protein L54, mitochondrial.
Cblc protein networkhttps://string-db.org/network/10090.ENSMUSP00000039955E3 ubiquitin-protein ligase CBL-C; Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting th [...]
Ripor1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039966Rho family-interacting cell polarization regulator 1; Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter prote [...]
Hykk protein networkhttps://string-db.org/network/10090.ENSMUSP00000039980Hydroxylysine kinase; Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L- lysine; Belongs to the aminoglycoside phosphotransferase family.
Slc25a37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000039990Mitoferrin-1; Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into [...]
Traip protein networkhttps://string-db.org/network/10090.ENSMUSP00000040001E3 ubiquitin-protein ligase TRAIP; E3 ubiquitin ligase acting as a negative regulator of innate immune signaling. Inhibits activation of NF-kappa-B mediated by TNF. Negatively regulates TLR3/4- a [...]
Rbm42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040005RNA-binding protein 42; Binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA.
Piezo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040019Piezo-type mechanosensitive ion channel component 2; Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotr [...]
Flywch1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040022FLYWCH-type zinc finger-containing protein 1.
Herc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040025Hect domain and RLD 3.
Npffr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040033Neuropeptide FF receptor 2; Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occu [...]
Usp31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040037Ubiquitin-specific peptidase 31; Belongs to the peptidase C19 family.
Ranbp10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040045Ran-binding protein 10; May act as an adapter protein to couple membrane receptors to intracellular signaling pathways (Probable). Core component of the CTLH E3 ubiquitin-protein ligase complex t [...]
Acer2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040048Alkaline ceramidase 2; Golgi ceramidase that catalyzes the hydrolysis of ceramides into sphingoid bases like sphingosine and free fatty acids at alkaline pH. Ceramides, sphingosine, and its phosp [...]
Odf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040050Outer dense fiber protein 4; Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskel [...]
Slfn8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040060Schlafen family member 8; Endoribonuclease that cleaves tRNAs and rRNAs. Cleaves tRNAs 11 nucleotides from the 3'-terminus at the acceptor stem. May be involved in immune system via regulation of [...]
Ica1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040062Islet cell autoantigen 1; May play a role in neurotransmitter secretion.
Sobp protein networkhttps://string-db.org/network/10090.ENSMUSP00000040072Sine oculis-binding protein homolog; Implicated in development of the cochlea.
Dse protein networkhttps://string-db.org/network/10090.ENSMUSP00000040074Dermatan-sulfate epimerase; Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues.
Zswim4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040078Zinc finger SWIM domain-containing protein 4.
Ccno protein networkhttps://string-db.org/network/10090.ENSMUSP00000040083Cyclin-O; Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS t [...]
Twist1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040089Twist-related protein 1; Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through phy [...]
4932438H23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000040111Uncharacterized protein C21orf62 homolog.
Hoxb7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040121Homeobox protein Hox-B7; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Kank3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040126KN motif and ankyrin repeat domain-containing protein 3; May be involved in the control of cytoskeleton formation by regulating actin polymerization.
C330007P06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000040134UPF0428 protein CXorf56 homolog.
Cox10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040138Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O.
Fhl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040150Four and a half LIM domains protein 3; Recruited by SOX15 to FOXK1 promoters where it acts as a transcriptional coactivator of FOXK1.
Reep4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040162Receptor expression-enhancing protein 4; Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from ch [...]
Fbxo45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040168F-box/SPRY domain-containing protein 1; Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Plays a role in the [...]
Adamts2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040171A disintegrin and metalloproteinase with thrombospondin motifs 2; Cleaves the propeptides of type I and II collagen prior to fibril assembly (By similarity). Does not act on type III collagen (By [...]
Esm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040187Endothelial cell-specific molecule 1; Involved in angiogenesis; promotes angiogenic sprouting. May have potent implications in lung endothelial cell-leukocyte interactions (By similarity).
Slc25a23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040198Calcium-binding mitochondrial carrier protein SCaMC-3; Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mi [...]
Creb3l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040208Processed cyclic AMP-responsive element-binding protein 3-like protein 2; Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, in [...]
Slc44a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040210Choline transporter-like protein 3.
Zc3h12d protein networkhttps://string-db.org/network/10090.ENSMUSP00000040217Probable ribonuclease ZC3H12D; May regulate cell growth likely by suppressing RB1 phosphorylation (By similarity). May function as RNase and regulate the levels of target RNA species (Potential). [...]
Ubac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040220Ubiquitin-associated domain-containing protein 1; Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degra [...]
Gask1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000040221Golgi-associated kinase 1A; Belongs to the GASK family.
Lap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040222Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides [...]
Dtx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040229E3 ubiquitin-protein ligase DTX4; Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires intera [...]
Sostdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040230Sclerostin domain-containing protein 1; May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits [...]
Wapl protein networkhttps://string-db.org/network/10090.ENSMUSP00000040232Wings apart-like protein homolog; Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion durin [...]
1700066M21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000040240UPF0565 protein C2orf69 homolog.
Akr1b8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040244Aldose reductase-related protein 2.
Irf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040245Interferon regulatory factor 8; Plays a role as a transcriptional activator or repressor (By similarity). Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC [...]
C1qb protein networkhttps://string-db.org/network/10090.ENSMUSP00000040246Complement C1q subcomponent subunit B; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact wi [...]
Zkscan8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040248Zinc finger with KRAB and SCAN domains 8.
Rbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040249Retinol-binding protein 3; IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina.
Aoc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040255Retina-specific copper amine oxidase; Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis. May be a critical modulat [...]
Tecta protein networkhttps://string-db.org/network/10090.ENSMUSP00000040262Alpha-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepit [...]
Tnfsf10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040271Tumor necrosis factor ligand superfamily member 10; Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces a [...]
Zfp715 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040282Zinc finger protein 715.
Anapc15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040286Anaphase-promoting complex subunit 15; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the [...]
Trim60 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040299Tripartite motif-containing protein 60; Belongs to the TRIM/RBCC family.
Tssk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040302Testis-specific serine/threonine-protein kinase 1; Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-281' of TSKS. Involved in the late st [...]
Map3k7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040307Mitogen-activated protein kinase kinase kinase 7; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascad [...]
Larp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040309La-related protein 6; Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure [...]
Inha protein networkhttps://string-db.org/network/10090.ENSMUSP00000040310Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of divers [...]
Ppp2r2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000040321Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform; B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis [...]
Asb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040331Ankyrin repeat and SOCS box protein 4; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquiti [...]
Prrx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040332Paired mesoderm homeobox protein 2; Belongs to the paired homeobox family.
Pcsk1n protein networkhttps://string-db.org/network/10090.ENSMUSP00000040342Big PEN-LEN; May function in the control of the neuroendocrine secretory pathway. Proposed be a specific endogenous inhibitor of PCSK1. ProSAAS and Big PEN-LEN, both containing the C-terminal inh [...]
Tmco3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040347Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter.
Gtf2h5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040355General transcription factor IIH subunit 5; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotid [...]
Hgsnat protein networkhttps://string-db.org/network/10090.ENSMUSP00000040356Heparan-alpha-glucosaminide N-acetyltransferase; Lysosomal acetyltransferase that acetylates the non-reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, conv [...]
Zcchc14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040360Zinc finger CCHC domain-containing protein 14.
Neurod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040364Neurogenic differentiation factor 1; Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associ [...]
Trpm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040367Transient receptor potential cation channel subfamily M member 4; Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in [...]
Fut11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040370Alpha-(1,3)-fucosyltransferase 11; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family.
Pnrc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040377Proline-rich nuclear receptor coactivator 1.
Alkbh4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040403Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4; Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-process [...]
Vwa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040405Von Willebrand factor A domain-containing protein 1; Promotes matrix assembly.
Tnfsf9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040412Tumor necrosis factor ligand superfamily member 9; Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation- induced cell dea [...]
Dlgap5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040416Disks large-associated protein 5; Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key [...]
Rbm45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040420RNA-binding protein 45; RNA-binding protein with binding specificity for poly(C). May play an important role in neural development (By similarity).
Pbxip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040429Pre-B-cell leukemia transcription factor-interacting protein 1; Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks [...]
Camkv protein networkhttps://string-db.org/network/10090.ENSMUSP00000040430CaM kinase-like vesicle-associated protein; Does not appear to have detectable kinase activity.
Stub1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040431STIP1 homology and U box-containing protein 1; E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Collaborates with ATXN3 in the degradation [...]
Inka1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040433PAK4-inhibitor INKA1; Inhibitor of the serine/threonine-protein kinase PAK4. Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity; Belongs to the INKA family.
H2-M1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040435Histocompatibility 2, M region locus 1; Belongs to the MHC class I family.
Lgi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040436Leucine-rich repeat LGI family member 2; Required for the development of soma-targeting inhibitory GABAergic synapses made by parvalbumin-positive basket cells.
Pbx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040464Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1 (By similarity).
Abca13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040465ATP-binding cassette sub-family A member 13.
Fshr protein networkhttps://string-db.org/network/10090.ENSMUSP00000040477Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signa [...]
Rnf122 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040478RING finger protein 122; May induce necrosis and apoptosis. May play a role in cell viability (By similarity).
Upk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040481Uroplakin-2; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating t [...]
Hlx protein networkhttps://string-db.org/network/10090.ENSMUSP00000040505H2.0-like homeobox protein; Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and h [...]
Kiss1r protein networkhttps://string-db.org/network/10090.ENSMUSP00000040516KiSS-1 receptor; Receptor for metastin (kisspeptin-52 or kp-52), a C- terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein. Activation of the receptor inhibits cell prol [...]
Slc16a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040522Monocarboxylate transporter 3; Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-cha [...]
Aicda protein networkhttps://string-db.org/network/10090.ENSMUSP00000040524Single-stranded DNA cytosine deaminase; Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lympho [...]
D630003M21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000040546Uncharacterized protein KIAA1755 homolog.
Kcnh3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040548Potassium voltage-gated channel subfamily H member 3; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be [...]
Maob protein networkhttps://string-db.org/network/10090.ENSMUSP00000040550Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in th [...]
Adat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040551Probable inactive tRNA-specific adenosine deaminase-like protein 3.
Gm7030 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040558Predicted gene 7030; Belongs to the MHC class I family.
Armc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040568Armadillo repeat-containing protein 5; Involved in fetal development, T-cell function and adrenal gland growth homeostasis. Negatively regulates adrenal cells survival. Plays a role in steroidoge [...]
Sfmbt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040575Scm-like with four MBT domains protein 2; Transcriptional repressor of HOXB13 gene.
Heyl protein networkhttps://string-db.org/network/10090.ENSMUSP00000040576Hairy/enhancer-of-split related with YRPW motif-like protein; Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (By similarity). Downstream effecto [...]
Bmt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040578S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts a [...]
Galm protein networkhttps://string-db.org/network/10090.ENSMUSP00000040580Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity).
Iqcc protein networkhttps://string-db.org/network/10090.ENSMUSP00000040584IQ domain-containing protein C.
Tbc1d19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040585TBC1 domain family, member 19.
Aldh5a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040591Succinate-semialdehyde dehydrogenase, mitochondrial; Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA); Belongs to the aldehyde dehydrogenase [...]
Palm protein networkhttps://string-db.org/network/10090.ENSMUSP00000040596Paralemmin-1; Involved in plasma membrane dynamics and cell process formation. Isoform 1 and isoform 2 are necessary for axonal and dendritic filopodia induction, for dendritic spine maturation a [...]
Vnn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040599Pantetheinase; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.
Tcfl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040611Transcription factor-like 5 (basic helix-loop-helix).
Phlda3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040614Pleckstrin homology-like domain family A member 3; p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 transl [...]
Wdtc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040647WD and tetratricopeptide repeats protein 1; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Rbpj protein networkhttps://string-db.org/network/10090.ENSMUSP00000040694Recombining binding protein suppressor of hairless; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates [...]
Mgarp protein networkhttps://string-db.org/network/10090.ENSMUSP00000040703Protein MGARP; Plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hyp [...]
Batf protein networkhttps://string-db.org/network/10090.ENSMUSP00000040706Basic leucine zipper transcriptional factor ATF-like; AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system: specifically mediates the [...]
Heca protein networkhttps://string-db.org/network/10090.ENSMUSP00000040707Hdc homolog, cell cycle regulator.
Cysltr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040715Cysteinyl leukotriene receptor 2; Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank ord [...]
Cox8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000040717Cytochrome c oxidase subunit 8A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The re [...]
Sem1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000004074126S proteasome complex subunit SEM1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in [...]
Cd207 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040746C-type lectin domain family 4 member K; Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superim [...]
Atp6v1h protein networkhttps://string-db.org/network/10090.ENSMUSP00000040756V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar [...]
Tent4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000040757Terminal nucleotidyltransferase 4A; Terminal nucleotidyltransferase that catalyzes preferentially the transfert of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail lead [...]
Cep104 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040762Centrosomal protein of 104 kDa; Required for ciliogenesis and for structural integrity at the ciliary tip.
Ttc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040771Tetratricopeptide repeat protein 7A; Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinosit [...]
Chst2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040775Carbohydrate sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetyl [...]
Ttc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040779Tetratricopeptide repeat protein 1.
AA467197 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040781Normal mucosa of esophagus-specific gene 1 protein.
Npy6r protein networkhttps://string-db.org/network/10090.ENSMUSP00000040797Neuropeptide Y receptor type 6; Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY = PYY >= NPY (2-36) = [Leu-31, Pro-34] N [...]
Nhsl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040799NHS-like protein 1.
Haus8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040802HAUS augmin-like complex subunit 8; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex; Belongs to [...]
Chrm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040808Muscarinic acetylcholine receptor M4; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modu [...]
Mospd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040828Motile sperm domain-containing protein 3.
Apmap protein networkhttps://string-db.org/network/10090.ENSMUSP00000040840Adipocyte plasma membrane-associated protein; Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate (By similarity). May play a role in adipocyte differentiation.
Pak1ip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040846P21-activated protein kinase-interacting protein 1; Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation [...]
Adrb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040847Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norep [...]
Wdr5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000040852WD repeat-containing protein 5B; May function as a substrate receptor for CUL4-DDB1 ubiquitin E3 ligase complex; Belongs to the WD repeat WDR5/wds family.
Agmat protein networkhttps://string-db.org/network/10090.ENSMUSP00000040853Agmatinase, mitochondrial.
Tmc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040859Transmembrane channel-like protein 1; Probable ion channel required for the normal function of cochlear hair cells; Belongs to the TMC family.
Lum protein networkhttps://string-db.org/network/10090.ENSMUSP00000040877Lumican; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
Erich6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040882Glutamate-rich protein 6; Belongs to the ERICH6 family.
Tmem246 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040885Transmembrane protein 246.
Tsga13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040894Testis-specific gene 13 protein.
Socs7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040896Suppressor of cytokine signaling 7; Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 [...]
Nrn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040900Neuritin; Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.
Rfxap protein networkhttps://string-db.org/network/10090.ENSMUSP00000040917Regulatory factor X-associated protein; Part of the RFX complex that binds to the X-box of MHC II promoters.
Hs3st6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040919Heparan sulfate glucosamine 3-O-sulfotransferase 6; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to heparan sulfate. Unlike 3-OST [...]
Hoxa11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040920Homeobox protein Hox-A11; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posteri [...]
Pnmal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040929Paraneoplastic antigen-like protein 8A; Belongs to the PNMA family.
Sdhaf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040935Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) [...]
Cdk19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040936Cyclin-dependent kinase 19; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Wdr92 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040938WD repeat-containing protein 92; Seems to act as a modulator of apoptosis.
Stn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040944CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication [...]
Stag3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040945Cohesin subunit SA-3; Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently fo [...]
Ankib1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040946Ankyrin repeat and IBR domain-containing protein 1; Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes a [...]
Rbm48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040952RNA-binding protein 48.
Sccpdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000040956Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family.
4921524J17Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000040975UPF0547 protein C16orf87 homolog; Belongs to the UPF0547 family.
Traf3ip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000040977TRAF3-interacting JNK-activating modulator; May function as an adapter molecule that regulates TRAF3- mediated JNK activation.
Afp protein networkhttps://string-db.org/network/10090.ENSMUSP00000041006Alpha-fetoprotein; Binds estrogens, fatty acids and metals.
Slc4a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041007Anion exchange protein.
H2-Ab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041008H-2 class II histocompatibility antigen, A beta chain; Belongs to the MHC class II family.
Tesk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041009Dual specificity testis-specific protein kinase 2; Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and [...]
Btn1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041013Butyrophilin subfamily 1 member A1; May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the api [...]
Lsm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041022U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated (By similarity). Probably also part of an LSm sub [...]
Pkn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041025Serine/threonine-protein kinase N3; Contributes to invasiveness in malignant prostate cancer.
Pth2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041047Tuberoinfundibular peptide of 39 residues; Plays a role as a potent and selective agonist of PTH2R resulting in adenyl cyclase activation and intracellular calcium levels elevation. Induces prote [...]
Wdr18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041049WD repeat-containing protein 18; May play a role during development (By similarity). Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited [...]
Trmt10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000041052tRNA methyltransferase 10 homolog B; S-adenosyl-L-methionine-dependent guanine N(1)- methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs. Probably n [...]
Egr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041053E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2. Ma [...]
Kap protein networkhttps://string-db.org/network/10090.ENSMUSP00000041060Kidney androgen-regulated protein.
Hrh4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041061Histamine H4 receptor; The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activit [...]
Irf2bpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000041070Probable E3 ubiquitin-protein ligase IRF2BPL; Probable E3 ubiquitin protein ligase involved in the proteasome-mediated ubiquitin-dependent degradation of target proteins. Through the degradation [...]
Rgl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041082Ral guanine nucleotide dissociation stimulator-like 2; Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in [...]
Prss42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041088Serine protease 42; Plays a role in spermatogenesis. Involved in germ cell survival during meiosis; Belongs to the peptidase S1 family.
Aifm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041104Apoptosis-inducing factor 1, mitochondrial; Functions both as NADH oxidoreductase and as regulator of apoptosis (By similarity). In response to apoptotic stimuli, it is released from the mitochon [...]
Nmnat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041110Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; Nicotinamide/nicotinate-nucleotide adenylyltransferase that acts as an axon maintenance factor. Catalyzes the formation of NAD(+) [...]
Txndc11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041113Thioredoxin domain-containing protein 11; May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex co [...]
Foxa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041118Hepatocyte nuclear factor 3-alpha; Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differenti [...]
Ibtk protein networkhttps://string-db.org/network/10090.ENSMUSP00000041145Inhibitor of Bruton tyrosine kinase; Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. Down-regulates BTK kinase activity, leading to interferenc [...]
Mif protein networkhttps://string-db.org/network/10090.ENSMUSP00000041149Macrophage migration inhibitory factor; Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as [...]
Spcs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041152Signal peptidase complex subunit 2; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endopla [...]
Spon1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041157Spondin-1; Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in [...]
Nfkbiz protein networkhttps://string-db.org/network/10090.ENSMUSP00000041173NF-kappa-B inhibitor zeta; Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits [...]
Cyp2s1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041175Cytochrome P450 2S1; A cytochrome P450 monooxygenase involved in the metabolism of retinoids and eicosanoids. In epidermis, may contribute to the oxidative metabolism of all-trans-retinoic acid. [...]
Resf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041180Retroelement silencing factor 1; Plays a role in the regulation of imprinted gene expression, regulates repressive epigenetic modifications associated with SETDB1. Required for the recruitment or [...]
Psmf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041184Proteasome inhibitor PI31 subunit; Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the ac [...]
Slc22a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041186Solute carrier family 22 member 2; Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, fa [...]
Lrrc18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041199Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation.
Edem2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041202ER degradation-enhancing alpha-mannosidase-like protein 2; Involved in the endoplasmic reticulum-associated degradation (ERAD) pathway that targets misfolded glycoproteins for degradation in an N [...]
Abcb1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000041204ATP-dependent translocase ABCB1; Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membran [...]
Xkr8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041205XK-related protein 8, processed form; Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only p [...]
Eda2r protein networkhttps://string-db.org/network/10090.ENSMUSP00000041210Tumor necrosis factor receptor superfamily member 27; Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be m [...]
Jmjd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041220Bifunctional peptidase and (3S)-lysyl hydroxylase Jmjd7; Bifunctional enzyme that acts both as an endopeptidase and 2- oxoglutarate-dependent monoxygenase (By similarity). Endopeptidase that cle [...]
Mtmr12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041227Myotubularin-related protein 12; Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing [...]
Igsf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041232Immunoglobulin superfamily member 8; May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and [...]
Zc4h2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041236Zinc finger C4H2 domain-containing protein; Plays a role in interneurons differentiation. Involved in neuronal development and in neuromuscular junction formation.
Smg7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041241Protein SMG7; Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery invol [...]
Zfp704 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041242Zinc finger protein 704; Transcription factor which binds to RE2 sequence elements in the MYOD1 enhancer.
Ablim3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041243Actin-binding LIM protein 3; May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity.
Ubr7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041247Putative E3 ubiquitin-protein ligase UBR7; E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that [...]
Serpina3g protein networkhttps://string-db.org/network/10090.ENSMUSP00000041250Serine protease inhibitor A3G; Belongs to the serpin family.
Aldh1b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041260Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, n [...]
Usp22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041263Ubiquitin carboxyl-terminal hydrolase 22; Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histone [...]
Cnbd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041268Cyclic nucleotide-binding domain-containing protein 2; Essential for male fertility. Plays an important role in spermatogenesis and regulates sperm motility by controlling the development of the [...]
Map2k4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041282Dual specificity mitogen-activated protein kinase kinase 4; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component [...]
Ss18l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041288Calcium-responsive transactivator; Transcriptional activator which is required for calcium- dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to [...]
Asb17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041293Ankyrin repeat and SOCS box protein 17; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquit [...]
Sntb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041294Beta-1-syntrophin; Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and th [...]
Dnajc12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041298DnaJ homolog subfamily C member 12.
Usp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041299Ubiquitin carboxyl-terminal hydrolase 5; Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys- 48'-linked polyubiquitin [...]
Ankrd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041300Ankyrin repeat domain-containing protein 6; Recruits CKI-epsilon to the beta-catenin degradation complex that consists of AXN1 or AXN2 and GSK3-beta and allows efficient phosphorylation of beta-c [...]
Oscar protein networkhttps://string-db.org/network/10090.ENSMUSP00000041306Osteoclast-associated immunoglobulin-like receptor; Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation. Belongs to the leukocyte recepto [...]
Sgtb protein networkhttps://string-db.org/network/10090.ENSMUSP00000041307Small glutamine-rich tetratricopeptide repeat-containing protein beta; Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity; Belongs to the SGT family.
Zc3h7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000041308Zinc finger CCCH type-containing 7 A.
Caskin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041328Caskin-2.
Got1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041337Putative aspartate aminotransferase, cytoplasmic 2; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Ina protein networkhttps://string-db.org/network/10090.ENSMUSP00000041347Alpha-internexin; Class-IV neuronal intermediate filament that is able to self- assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the [...]
Fhod3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041361FH1/FH2 domain-containing protein 3; May play a role in actin filament polymerization in cardiomyocytes (By similarity). Actin-organizing protein that may cause stress fiber formation together wi [...]
Klhl35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041363Kelch-like protein 35.
Neurod2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041373Neurogenic differentiation factor 2; Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. C [...]
Ticrr protein networkhttps://string-db.org/network/10090.ENSMUSP00000041377Treslin; Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loadin [...]
Shtn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041378Shootin-1; Involved in the generation of internal asymmetric signals required for neuronal polarization and neurite outgrowth. Mediates netrin-1-induced F-actin-substrate coupling or 'clutch enga [...]
Chchd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041380Mitochondrial intermembrane space import and assembly protein 40; Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of [...]
Ppm1k protein networkhttps://string-db.org/network/10090.ENSMUSP00000041395Protein phosphatase 1K, mitochondrial; Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development. Belongs to the PP2C family.
Rhov protein networkhttps://string-db.org/network/10090.ENSMUSP00000041411Rho-related GTP-binding protein RhoV; Plays a role in the control of the actin cytoskeleton via activation of the JNK pathway; Belongs to the small GTPase superfamily. Rho family.
Lefty1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041427Left-right determination factor 1; Required for left-right axis determination as a regulator of LEFTY2 and NODAL; Belongs to the TGF-beta family.
Prpf18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041428Pre-mRNA-splicing factor 18; Participates in the second step of pre-mRNA splicing.
Slc23a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041436Solute carrier family 23 member 4.
Hsd3b5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041442NADPH-dependent 3-keto-steroid reductase Hsd3b5; Responsible for the reduction of the oxo group on the C-3 of 5alpha-androstane steroids. Catalyzes the conversion of dihydrotestosterone to its in [...]
Pdk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041447[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial; Kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphoryla [...]
Clic4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041453Chloride intracellular channel protein 4; Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane inse [...]
Wdr45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041456WD repeat domain phosphoinositide-interacting protein 4; Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged [...]
Rpp25l protein networkhttps://string-db.org/network/10090.ENSMUSP00000041477Ribonuclease P protein subunit p25-like protein; May be a component of ribonuclease P or MRP; Belongs to the histone-like Alba family.
Slitrk5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041499SLIT and NTRK-like protein 5; Suppresses neurite outgrowth; Belongs to the SLITRK family.
Arl6ip5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041503PRA1 family protein 3; Regulates intracellular concentrations of taurine and glutamate (By similarity). Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity f [...]
Sct protein networkhttps://string-db.org/network/10090.ENSMUSP00000041519Secretin; Hormone involved in different processes, such as regulation of the pH of the duodenal content, food intake and water homeostasis. Exerts its biological effects by binding to secretin re [...]
AW209491 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041523UPF0415 protein C7orf25 homolog; Belongs to the UPF0415 family.
Eif1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041538Eukaryotic translation initiation factor 1; Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of [...]
Asb10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041539Ankyrin repeat and SOCS box protein 10; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquit [...]
Faah protein networkhttps://string-db.org/network/10090.ENSMUSP00000041543Fatty-acid amide hydrolase 1; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to termin [...]
Slc7a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041557Large neutral amino acids transporter small subunit 1; The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids suc [...]
Fam110c protein networkhttps://string-db.org/network/10090.ENSMUSP00000041563Protein FAM110C; May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway.
Rspo4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041578R-spondin-4; Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 an [...]
Lgi4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041579Leucine-rich repeat LGI family member 4; Component of Schwann cell signaling pathway(s) that controls axon segregation and myelin formation.
March9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041581E3 ubiquitin-protein ligase MARCHF9; E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I, CD4 and ICAM1, and promote their subsequent endocytosis and sorting to lysosomes via mul [...]
Gm9758 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041597Predicted gene, ENSMUSG00000033219.
Helq protein networkhttps://string-db.org/network/10090.ENSMUSP00000041599Helicase POLQ-like; Single-stranded DNA-dependent ATPase and 5' to 3' DNA helicase. Involved in the repair of DNA cross-links and double-strand break (DSB) resistance. Participates in FANCD2-medi [...]
Akna protein networkhttps://string-db.org/network/10090.ENSMUSP00000041614Microtubule organization protein AKNA; Centrosomal protein that plays a key role in cell delamination by regulating microtubule organization. Required for the delamination and retention of neural [...]
Cercam protein networkhttps://string-db.org/network/10090.ENSMUSP00000041622Inactive glycosyltransferase 25 family member 3; Probable cell adhesion protein involved in leukocyte transmigration across the blood-brain barrier. Does not express any beta-galactosyltransferas [...]
Mgat4d protein networkhttps://string-db.org/network/10090.ENSMUSP00000041629Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D; [Isoform 2]: May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity caus [...]
Calm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041636Calmodulin-4; Implicated in the early stage of ectopic ossification.
Brk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041644Protein BRICK1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex (By similarity). As component of the WAVE1 complex, required [...]
Commd10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041650COMM domain-containing protein 10; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B.
Rpl21 protein networkhttps://string-db.org/network/10090.ENSMUSP0000004165260S ribosomal protein L21; Component of the large ribosomal subunit.
Chst12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041663Carbohydrate sulfotransferase 12; Catalyzes the transfer of sulfate to position 4 of the N- acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfat [...]
Gpr26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041664G-protein coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in [...]
Fam117b protein networkhttps://string-db.org/network/10090.ENSMUSP00000041671Protein FAM117B.
Cldn22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041676Claudin-22; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
Slc19a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041683Thiamine transporter 2; Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity (By similarity).
Kcnj12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041696ATP-sensitive inward rectifier potassium channel 12; Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling t [...]
Fbxl18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041700F-box and leucine-rich repeat protein 18.
Thada protein networkhttps://string-db.org/network/10090.ENSMUSP00000041701Thyroid adenoma-associated protein homolog.
Kcna2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041702Potassium voltage-gated channel subfamily A member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the centra [...]
Ifi27l2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000041712Interferon alpha-inducible protein 27-like protein 2B; Functions in the intrinsic apoptotic signaling pathway and may have an interferon-induced antiviral activity. Belongs to the IFI6/IFI27 fami [...]
Zdhhc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041727Palmitoyltransferase ZDHHC2; Palmitoyltransferase specific for GAP43 and DLG4/PSD95.
Ppp1r9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000041732Neurabin-2; Seems to act as a scaffold protein in multiple signaling pathways. Modulates excitatory synaptic transmission and dendritic spine morphology. Binds to actin filaments (F-actin) and sh [...]
3110001I22Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000041742RIKEN cDNA 3110001I22 gene.
Ofd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041744Oral-facial-digital syndrome 1 protein homolog; Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-speci [...]
Trib3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041747Tribbles homolog 3; Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr- 308' phosphorylation site in AKT1. Binds t [...]
Fbxw17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041750F-box and WD-40 domain protein 17.
Ankrd27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041751Ankyrin repeat domain-containing protein 27; May be a guanine exchange factor (GEF) for Rab21, Rab32 and Rab38 and regulate endosome dynamics (By similarity). May regulate the participation of VA [...]
Arl5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000041756ADP-ribosylation factor-like protein 5A; Lacks ADP-ribosylation enhancing activity.
Snapc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041767snRNA-activating protein complex subunit 4; Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence elem [...]
Gata6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041774Transcription factor GATA-6; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection (By similarity). Involved in gen [...]
Slc26a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041789Anion exchange transporter; Acts as a sodium-independent DIDS-sensitive anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. May play a role in the maintenance of the e [...]
Pcgf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041790Polycomb group RING finger protein 3; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes [...]
Elac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041793Zinc phosphodiesterase ELAC protein 1; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from p [...]
Rpl39l protein networkhttps://string-db.org/network/10090.ENSMUSP00000041794Ribosomal protein L39-like.
Zfp113 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041796Zinc finger protein 113.
E130309D02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000041800Uncharacterized protein C7orf26 homolog.
Neurl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041806Neuralized-like protein 2; Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-bo [...]
Bcdin3d protein networkhttps://string-db.org/network/10090.ENSMUSP00000041809RNA 5'-monophosphate methyltransferase; O-methyltransferase that specifically monomethylates 5'- monophosphate of cytoplasmic histidyl tRNA, acting as a capping enzyme. Less efficiently, also met [...]
Lonp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041814Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-l [...]
Map3k9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041819Mitogen-activated protein kinase kinase kinase 9; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascad [...]
Cox15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041820Cytochrome c oxidase assembly protein COX15 homolog; May be involved in the biosynthesis of heme A.
Zkscan2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041821Zinc finger with KRAB and SCAN domains 2.
Coro2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000041826Coronin-2B; May play a role in the reorganization of neuronal actin structure.
Sorcs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041828VPS10 domain-containing receptor SorCS2; The heterodimer formed by NGFR and SORCS2 functions as receptor for the precursor forms of NGF (proNGF) and BDNF (proBDNF). ProNGF and proBDNF binding bot [...]
Rbm17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041831Splicing factor 45; Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alterna [...]
Txndc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041839Thioredoxin domain-containing protein 5; Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast.
Dnajc17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041841DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription.
Trub2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041848Mitochondrial mRNA pseudouridine synthase Trub2; Minor enzyme contributing to the isomerization of uridine to pseudouridine (pseudouridylation) of specific mitochondrial mRNAs (mt- mRNAs) such as [...]
Dars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041851Aspartate--tRNA ligase, mitochondrial.
C8g protein networkhttps://string-db.org/network/10090.ENSMUSP00000041855Complement component C8 gamma chain; C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the pol [...]
Rab8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000041857Ras-related protein Rab-8B; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle bet [...]
Ap5z1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041863AP-5 complex subunit zeta-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport.
Sfxn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041872Sideroflexin-5; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). Transports c [...]
Egln3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041874Egl nine homolog 3; Plays a crucial role in DNA damage response (DDR) by hydroxylating TELO2, promoting its interaction with ATR which is required for activation of the ATR/CHK1/p53 pathway (By s [...]
Mreg protein networkhttps://string-db.org/network/10090.ENSMUSP00000041878Melanoregulin; Probably functions as cargo-recognition protein that couples cytoplasmic vesicles to the transport machinery. Plays a role in hair pigmentation, a process that involves shedding of [...]
Tspan10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041883Tetraspanin-10; Regulates maturation of the transmembrane metalloprotease ADAM10.
Syde2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041897Synapse defective 1, Rho GTPase, homolog 2 (C. elegans).
Asap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041899Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3; Promotes cell proliferation.
C130074G19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000041904Uncharacterized protein C1orf115 homolog.
Dis3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041906Exosome complex exonuclease RRP44; Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and [...]
F11r protein networkhttps://string-db.org/network/10090.ENSMUSP00000041907Junctional adhesion molecule A; Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-P [...]
Neil3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041909Endonuclease 8-like 3; DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displ [...]
Erf protein networkhttps://string-db.org/network/10090.ENSMUSP00000041912ETS domain-containing transcription factor ERF; Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation (By [...]
Ttc29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041919Tetratricopeptide repeat protein 29.
Cldn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041925Claudin-5; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
Adgrl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041939Adhesion G protein-coupled receptor L4; Endothelial orphan receptor that acts as a key regulator of angiogenesis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled re [...]
Zfp804a protein networkhttps://string-db.org/network/10090.ENSMUSP00000041941Zinc finger protein 804A.
Zfp324 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041944Zinc finger protein 324.
Gab3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041951GRB2-associated-binding protein 3.
Zbtb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041955Zinc finger and BTB domain-containing protein 1; Acts as a transcriptional repressor (By similarity). Represses cAMP-responsive element (CRE)-mediated transcriptional activation (By similarity). [...]
Muc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041963Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacteri [...]
Agps protein networkhttps://string-db.org/network/10090.ENSMUSP00000041967Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first et [...]
Psmd7 protein networkhttps://string-db.org/network/10090.ENSMUSP0000004196826S proteasome non-ATPase regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a k [...]
Baat protein networkhttps://string-db.org/network/10090.ENSMUSP00000041983Bile acid-CoA:amino acid N-acyltransferase; Catalyzes the amidation of bile acids (BAs) with the amino acid taurine. Selective for taurine conjugation of cholyl CoA and only taurine-conjugated BA [...]
Tex2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041985Testis-expressed protein 2.
Hesx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000041999Homeobox expressed in ES cells 1; Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland. Possible transcripti [...]
Eps8l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042004Epidermal growth factor receptor kinase substrate 8-like protein 3.
Fstl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042007Follistatin-related protein 4.
Bag2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042009BAG family molecular chaperone regulator 2; Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 p [...]
Acot5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042019Acyl-coenzyme A thioesterase 5; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to r [...]
D11Wsu47e protein networkhttps://string-db.org/network/10090.ENSMUSP00000042025Uncharacterized protein C17orf80 homolog.
Apobr protein networkhttps://string-db.org/network/10090.ENSMUSP00000042028Apolipoprotein B receptor; Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic [...]
Micall1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042053MICAL-like protein 1; Probable lipid-binding protein with higher affinity for phosphatidic acid, a lipid enriched in recycling endosome membranes. On endosome membranes, may act as a downstream e [...]
Cdcp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042057CUB domain-containing protein 1; May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiat [...]
Tekt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042063Tektin-3; May be a structural component of the sperm flagellum. Required for normal sperm mobility; Belongs to the tektin family.
Rab3gap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042070Rab3 GTPase-activating protein catalytic subunit; Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins [...]
Gnptg protein networkhttps://string-db.org/network/10090.ENSMUSP00000042073N-acetylglucosamine-1-phosphotransferase subunit gamma; Non-catalytic subunit of the N-acetylglucosamine-1- phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phospha [...]
Serpina3k protein networkhttps://string-db.org/network/10090.ENSMUSP00000042095Serine protease inhibitor A3K; Contrapsin inhibits trypsin-like proteases.
Lasp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042123LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regu [...]
Tsfm protein networkhttps://string-db.org/network/10090.ENSMUSP00000042134Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolys [...]
Rras protein networkhttps://string-db.org/network/10090.ENSMUSP00000042150Ras-related protein R-Ras; Regulates the organization of the actin cytoskeleton. With OSPBL3, modulates integrin beta-1 (ITGB1) activity. Belongs to the small GTPase superfamily. Ras family.
Rundc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042151RUN domain-containing protein 1; May play a role as p53/TP53 inhibitor and thus may have oncogenic activity.
Oxsr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042155Serine/threonine-protein kinase OSR1; Phosphorylates RELL1, RELL2, RELT and PAK1. Phosphorylates PLSCR1 in the presence of RELT.
Cpne7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042159Copine-7; Calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.
Dph1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000421622-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation el [...]
Ppp1r26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042173Protein phosphatase 1 regulatory subunit 26; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation.
Kank1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042177KN motif and ankyrin repeat domains 1.
Cldn11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042181Claudin-11; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
Ttc36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042183Tetratricopeptide repeat protein 36; Belongs to the TTC36 family.
Ndufa4l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042185NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2; Belongs to the complex I NDUFA4 subunit family.
Abcc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042186ATP-binding cassette, sub-family C (CFTR/MRP), member 4.
Smpd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042187Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2- diacylglycerolphosphoglycerol; Belongs to [...]
Tpcn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042188Two pore calcium channel protein 1; Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal [...]
Cdh10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042199Cadherin-10; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the [...]
Med30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042204Mediator of RNA polymerase II transcription subunit 30; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Ago2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042207Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a [...]
Sema7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000042211Semaphorin-7A; Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activat [...]
Atp8a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042215Phospholipid-transporting ATPase IA; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the [...]
Fbxl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042219F-box/LRR-repeat protein 4.
Myo5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000042229Myosin VC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Hebp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042232Heme-binding protein 1; May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of [...]
Tmco5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000042247Transmembrane and coiled-coil domain-containing protein 5B.
Ncapd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042260Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex p [...]
Gtf3c4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042265General transcription factor 3C polypeptide 4; Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus- associated (VA) RNA [...]
Spag9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042271C-Jun-amino-terminal kinase-interacting protein 4; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK c [...]
Cybc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042277Cytochrome b-245 chaperone 1; Necessary for a stable expression of the CYBA and CYBB subunits of the cytochrome b-245 heterodimer. Controls the phagocyte respiratory burst and is essential for in [...]
Supt16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042283FACT complex subunit SPT16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a [...]
Ldah protein networkhttps://string-db.org/network/10090.ENSMUSP00000042285Lipid droplet-associated hydrolase; Serine lipid hydrolase associated with lipid droplets. Highly expressed in macrophage-rich areas in atherosclerotic lesions, suggesting that it could promote c [...]
Chd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042291Chromodomain-helicase-DNA-binding protein 6; DNA-dependent ATPase that plays a role in chromatin remodeling. Regulates transcription by disrupting nucleosomes in a largely non-sliding manner whic [...]
Pcnx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042294Pecanex-like protein 2; May play a role in tumorigenesis.
Shisal2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000042302Protein shisa-like-2B.
Dsc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042303Desmocollin-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal [...]
Igflr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042312IGF-like family receptor 1; Probable cell membrane receptor for the IGF-like family protein IGFL.
Tmem45b protein networkhttps://string-db.org/network/10090.ENSMUSP00000042313Transmembrane protein 45B.
Nfkbid protein networkhttps://string-db.org/network/10090.ENSMUSP00000042317NF-kappa-B inhibitor delta; Regulates the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. Involved [...]
Zscan2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042321Zinc finger and SCAN domain-containing protein 2; May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis.
Lpar6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042327Lysophosphatidic acid receptor 6; Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation. Important for the maintenance of hair growth and [...]
Plekhj1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042334Pleckstrin homology domain-containing family J member 1.
Tubb4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000042342Tubulin beta-4B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha c [...]
Efhc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042343EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. N [...]
Acaa1a protein networkhttps://string-db.org/network/10090.ENSMUSP000000423513-ketoacyl-CoA thiolase A, peroxisomal.
Acsbg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042352Long-chain-fatty-acid--CoA ligase ACSBG2; Catalyzes the conversion of fatty acids such as long chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular [...]
Myl12b protein networkhttps://string-db.org/network/10090.ENSMUSP00000042364Myosin regulatory light chain 12B; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phos [...]
Hspb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042374Heat shock protein beta-2; May regulate the kinase DMPK; Belongs to the small heat shock protein (HSP20) family.
Svs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042389Seminal vesicle secretory protein 2.
Traf3ip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042391TRAF3-interacting protein 1; Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-bind [...]
Scn7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000042405Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the mem [...]
Tmprss11b protein networkhttps://string-db.org/network/10090.ENSMUSP00000042406Transmembrane protease serine 11B-like protein; Serine protease; Belongs to the peptidase S1 family.
Slc30a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042410Zinc transporter 1; May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention; Belongs to [...]
Dlx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042413Homeobox protein DLX-1; Plays a role as a transcriptional activator or repressor. Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the tra [...]
Tmem177 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042416Transmembrane protein 177; Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT- [...]
Ddx58 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042433Antiviral innate immune response receptor RIG-I; Innate immune receptor that senses cytoplasmic viral nucleic acids and activates a downstream signaling cascade leading to the production of type [...]
Eef1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042457Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that ac [...]
Thap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042464THAP domain-containing protein 1; DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT [...]
Calhm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042466Calcium homeostasis modulator protein 4; Pore-forming subunit of a voltage-gated ion channel. Belongs to the CALHM family.
Wdr48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042509WD repeat-containing protein 48; Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 and USP46. Enhances the USP1-mediated deubiquitination of FANCD2; USP1 being almost in [...]
H2-M11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042522Histocompatibility 2, M region locus 11; Belongs to the MHC class I family.
Kif16b protein networkhttps://string-db.org/network/10090.ENSMUSP00000042551Kinesin-like protein KIF16B; Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early [...]
Klhl42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042558Kelch-like protein 42; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligas [...]
Cdc42bpb protein networkhttps://string-db.org/network/10090.ENSMUSP00000042565Serine/threonine-protein kinase MRCK beta; Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and [...]
Rnf113a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042569Ring finger protein 113A1.
Spata20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042572Spermatogenesis-associated protein 20; May play a role in fertility regulation.
Trhr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042575Thyrotropin-releasing hormone receptor 2; Belongs to the G-protein coupled receptor 1 family.
AW551984 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042582Expressed sequence AW551984.
Cep44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042586Centrosomal protein of 44 kDa.
Psma8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042590Proteasome subunit alpha type-8; Component of the spermatoproteasome, a proteasome specifically found in testis that promotes acetylation-dependent degradation of histones, thereby participating [...]
Apex1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042602DNA-(apurinic or apyrimidinic site) lyase, mitochondrial; Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 are DNA [...]
Cd99l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042606CD99 antigen-like protein 2; Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PE [...]
Lilra6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042636Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6.
Il22ra2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042642Interleukin-22 receptor subunit alpha-2; Receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an importan [...]
Hnrnpa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042658Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed; Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may [...]
Hyal3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042667Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Invol [...]
Rmi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042676RecQ-mediated genome instability protein 2; Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is requi [...]
Ddx21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042691Nucleolar RNA helicase 2; RNA helicase that acts as a sensor of the transcriptional status of both RNA polymerase (Pol) I and II: promotes ribosomal RNA (rRNA) processing and transcription from p [...]
Cyth4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042698Cytohesin-4; Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP (By similarity).
Spon2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042701Spondin-2; Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage [...]
Rpgrip1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000042702Protein fantom; Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R) (By similarity). May be involved in mechanisms like programmed cell death, craniofaci [...]
Gng10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042705Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling s [...]
Gpr34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042715Probable G-protein coupled receptor 34; Orphan receptor.
Nkx6-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042716Homeobox protein Nkx-6.1; Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Required for the development of insulin-producing beta [...]
Zc3h10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042727Zinc finger CCCH domain-containing protein 10; Specific regulator of miRNA biogenesis. Binds, via the C3H1- type zinc finger domains, to the binding motif 5'-GCAGCGC-3' on microRNA pri-MIR143 and [...]
Slc22a23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042742Solute carrier family 22 member 23; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
Pphln1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042762Periphilin-1; Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to [...]
Ccdc114 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042772Coiled-coil domain-containing protein 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms. Belongs to the ODA1/DCC2 family [...]
Tmem135 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042783Transmembrane protein 135; Involved in mitochondrial metabolism by regulating the balance between mitochondrial fusion and fission. May act as a regulator of mitochondrial fission that promotes D [...]
Ak5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042785Adenylate kinase isoenzyme 5; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Act [...]
Msl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042792Male-specific lethal 1 homolog; Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac) which is implicated in the formation of [...]
Eri3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042796ERI1 exoribonuclease 3.
March4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042803E3 ubiquitin-protein ligase MARCHF4; E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesic [...]
Npepl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042808Probable aminopeptidase NPEPL1; Probably catalyzes the removal of unsubstituted N-terminal amino acids from various peptides; Belongs to the peptidase M17 family.
Tmem98 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042825Transmembrane protein 98; Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-f [...]
1700017N19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000042828RIKEN cDNA 1700017N19 gene.
Parm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042844Prostate androgen-regulated mucin-like protein 1 homolog; May regulate TLP1 expression and telomerase activity, thus enabling certain prostatic cells to resist apoptosis.
Tmem33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042852Transmembrane protein 33; Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules. Positively regulates PERK-mediated and [...]
Dnah3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042857Dynein heavy chain 3, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke [...]
Gnpnat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042860Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily.
Wnt8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000042867Protein Wnt-8b; Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, nota [...]
Appl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042875DCC-interacting protein 13-alpha; Multifunctional adapter protein that binds to various membrane receptors, nuclear factors and signaling proteins to regulate many processes, such as cell prolife [...]
Mrm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042882rRNA methyltransferase 3, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S [...]
C1rl protein networkhttps://string-db.org/network/10090.ENSMUSP00000042883Complement C1r subcomponent-like protein; Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.
9130409I23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000042889RIKEN cDNA 9130409I23 gene.
Cep126 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042904Centrosomal protein of 126 kDa; Participate in cytokinesis (By similarity). Necessary for microtubules and mitotic spindle organization (By similarity). Involved in primary cilium formation (By s [...]
Ccdc115 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042918Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, requ [...]
Tmem51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042919Transmembrane protein 51.
Dner protein networkhttps://string-db.org/network/10090.ENSMUSP00000042927Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development [...]
Tlcd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042958TLC domain-containing protein 2; Regulates the composition and fluidity of the plasma membrane (By similarity). Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 [...]
Fcho2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042959F-BAR domain only protein 2; Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formati [...]
Ndufv1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042967NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minima [...]
Rps6ka5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042987Ribosomal protein S6 kinase alpha-5; Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the reg [...]
Thrsp protein networkhttps://string-db.org/network/10090.ENSMUSP00000042988Thyroid hormone-inducible hepatic protein; Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length [...]
Obox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000042995Oocyte-specific homeobox 2.
Gucd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043000Protein GUCD1.
Tsga8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043015Testis-specific gene A8 protein.
Cdc123 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043033Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle; Belongs to the CDC123 family.
Ccdc138 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043040Coiled-coil domain-containing protein 138.
Abhd11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043041Protein ABHD11; Belongs to the AB hydrolase superfamily.
Exd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043049Exonuclease 3'-5' domain-containing protein 2; Exonuclease that has both 3'-5' exoribonuclease and exodeoxyribonuclease activities, depending on the divalent metal cation used as cofactor. In pre [...]
Adgrg6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043055Adhesion G-protein coupled receptor G6; G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane. Essential for normal differentiation of pr [...]
Mpst protein networkhttps://string-db.org/network/10090.ENSMUSP000000430613-mercaptopyruvate sulfurtransferase; Transfer of a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Detoxifies cyanide and is required for thiosulfate biosynt [...]
Hs2st1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043066Heparan sulfate 2-O-sulfotransferase 1; Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, [...]
Sncb protein networkhttps://string-db.org/network/10090.ENSMUSP00000043074Beta-synuclein; May be involved in neuronal plasticity.
Mgat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043077Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase; It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the [...]
Hoxd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043078Homeobox protein Hox-D1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Syde1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043085Rho GTPase-activating protein SYDE1; GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells m [...]
Cbfa2t2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043087Protein CBFA2T2; Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and hist [...]
Daglb protein networkhttps://string-db.org/network/10090.ENSMUSP00000043088Sn1-specific diacylglycerol lipase beta; Catalyzes the hydrolysis of diacylglycerol (DAG) to 2- arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal gro [...]
Blvrb protein networkhttps://string-db.org/network/10090.ENSMUSP00000043092Flavin reductase (NADPH); Broad specificity oxidoreductase that catalyzes the NADPH- dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQ [...]
Tlr13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043101Toll-like receptor 13; Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens throug [...]
R3hdm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043103R3H domain-containing 1.
Brip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043108Fanconi anemia group J protein homolog; DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the 'Fanconi anemia' pathway, after FANC [...]
Rpl22l1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000004311160S ribosomal protein L22-like 1.
Bex2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043113Protein BEX2; Regulator of mitochondrial apoptosis and G1 cell cycle. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity (By similarity); Belongs to the BEX family.
Heatr5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000043115HEAT repeat-containing protein 5A.
Rbm24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043120RNA-binding protein 24; Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiati [...]
Srrt protein networkhttps://string-db.org/network/10090.ENSMUSP00000043123Serrate RNA effector molecule homolog; Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to t [...]
Cmtm2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000043127CKLF-like MARVEL transmembrane domain-containing protein 2B; Belongs to the chemokine-like factor family.
Bahd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043130Bromo adjacent homology domain-containing 1 protein; Heterochromatin protein that acts as a transcription repressor and has the ability to promote the formation of large heterochromatic domains. [...]
Phf20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043138PHD finger protein 20; Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage (By similarity). Methyllysine- binding protein, component of the MOF histone [...]
Raver2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043142Ribonucleoprotein PTB-binding 2; May bind single-stranded nucleic acids.
BC055324 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043143Uncharacterized protein C1orf112 homolog.
Ak7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043145Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest a [...]
Shc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043146SHC-transforming protein 4; Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.
Amh protein networkhttps://string-db.org/network/10090.ENSMUSP00000043153Muellerian-inhibiting factor; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived fro [...]
Gns protein networkhttps://string-db.org/network/10090.ENSMUSP00000043167N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.
Foxa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043173Hepatocyte nuclear factor 3-gamma; Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core [...]
Usp6nl protein networkhttps://string-db.org/network/10090.ENSMUSP00000043178USP6 N-terminal-like protein; Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrogr [...]
Gna11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043190Guanine nucleotide-binding protein subunit alpha-11; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as [...]
Fkbp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043193Inactive peptidyl-prolyl cis-trans isomerase FKBP6; Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germli [...]
Guca2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000043203Guanylate cyclase activator 2B; Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a [...]
Polr2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000043204DNA-directed RNA polymerases I, II, and III subunit RPABC5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Com [...]
Katnal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043210Katanin p60 ATPase-containing subunit A-like 1; Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-d [...]
Siah1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000043215E3 ubiquitin-protein ligase SIAH1B; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from [...]
Chst7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043222Carbohydrate sulfotransferase 7; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetyl [...]
Vps13d protein networkhttps://string-db.org/network/10090.ENSMUSP00000043240Vacuolar protein sorting 13D.
Ubac2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043245Ubiquitin-associated domain-containing protein 2; Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets (By similarity). In association with LMBR1L and E3 ubiquitin-prote [...]
Fras1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043250Extracellular matrix protein FRAS1; Belongs to the FRAS1 family.
Zdhhc17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043279Palmitoyltransferase ZDHHC17; Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HTT. May be involved in the sorting or targeting of cri [...]
Dnah1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043281Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the for [...]
Pnpla8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043286Calcium-independent phospholipase A2-gamma; Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. [...]
Ptger3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043302Prostaglandin E2 receptor EP3 subtype; Receptor for prostaglandin E2 (PGE2). Required for normal development of fever in response to pyrinogens, including IL1B, prostaglandin E2 and bacterial lip [...]
Glyat protein networkhttps://string-db.org/network/10090.ENSMUSP00000043308Glycine N-acyltransferase; Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate a multitude of sub [...]
Wdr74 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043315WD repeat-containing protein 74; Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processi [...]
Scgb3a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043325Secretoglobin family 3A member 1; Secreted cytokine-like protein. Inhibits cell growth in vitro.
Msantd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043329Myb/SANT-like DNA-binding domain-containing protein 2.
Map6d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043332MAP6 domain-containing protein 1; May have microtubule-stabilizing activity.
Mgat4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000043346Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B; Glycosyltransferase that participates in the transfer of N- acetylglucosamine (GlcNAc) to the core mannose residues of N- [...]
Rmnd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043355Required for meiotic nuclear division protein 1 homolog; Required for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome.
Il5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043369Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.
Slc25a16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043370Graves disease carrier protein homolog; Required for the accumulation of coenzyme A in the mitochondrial matrix.
Rln1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043376Relaxin A chain; Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals.
Spata16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043378Spermatogenesis-associated protein 16; Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion. Belongs to the SPATA16 family.
Icmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000043390Protein-S-isoprenylcysteine O-methyltransferase; Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues; Belongs to the class VI-like SAM-binding methyltransfe [...]
Cluap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043397Clusterin-associated protein 1; Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling.
Ppip5k2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043401Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphos [...]
2410131K14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000043410UPF0454 protein C12orf49 homolog.
Scaper protein networkhttps://string-db.org/network/10090.ENSMUSP00000043411S phase cyclin A-associated protein in the ER.
Rtp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043416Receptor-transporting protein 1; Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs. Belongs to the TMEM7 family.
Acad11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043424Acyl-CoA dehydrogenase family member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA. Probably participates to beta-oxydation and energy production but could [...]
Ric1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043437RAB6A-GEF complex partner protein 1; The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required [...]
Klhdc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043439Kelch domain-containing protein 4.
Ccdc93 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043442Coiled-coil domain-containing protein 93; Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and [...]
1700013G24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000043461RIKEN cDNA 1700013G24 gene.
Asb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043462Ankyrin repeat and SOCS box protein 6; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquiti [...]
Agap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043466Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Participates in the prevention of n [...]
Dhrs11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043467Dehydrogenase/reductase SDR family member 11; Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta- hydroxyl metabolites and t [...]
St8sia4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043477CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase; Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on t [...]
Xpot protein networkhttps://string-db.org/network/10090.ENSMUSP00000043488Exportin-T; Mediates the nuclear export of aminoacylated tRNAs. In the nucleus binds to tRNA and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear po [...]
Setd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043492Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcr [...]
Sprr2i protein networkhttps://string-db.org/network/10090.ENSMUSP00000043513Small proline-rich protein 2I; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane [...]
Exosc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043519Exosome complex component RRP4; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrada [...]
Cst10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043520Cystatin 10; May play a role in the last steps of the chondrocyte differentiation pathway as an inducer of maturation. Induces chondrocyte calcification during endochondral ossification by playin [...]
H2-DMb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043526Histocompatibility 2, class II, locus Mb2.
Sft2d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043537Vesicle transport protein SFT2B; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.
Krtcap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043540Keratinocyte-associated protein 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the l [...]
Ndufb10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043543NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved [...]
Taar9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043552Trace amine-associated receptor 9; Orphan olfactory receptor specific for trace amines. Belongs to the G-protein coupled receptor 1 family.
Dok4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043554Docking protein 4; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in [...]
Smg6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043555Telomerase-binding protein EST1A; Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regu [...]
Cisd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043559CDGSH iron-sulfur domain-containing protein 1; Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/ [...]
Mrpl41 protein networkhttps://string-db.org/network/10090.ENSMUSP0000004356139S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p5 [...]
Pank1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043562Pantothenate kinase 1; Plays a role in the physiological regulation of the intracellular CoA concentration; Belongs to the type II pantothenate kinase family.
Dsel protein networkhttps://string-db.org/network/10090.ENSMUSP00000043570Dermatan-sulfate epimerase-like protein.
Gtpbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043575GTP-binding protein 1; Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity).
Alg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043580Alpha-1,3/1,6-mannosyltransferase ALG2; Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
Bclaf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043583Bcl-2-associated transcription factor 1; Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'en [...]
Tex45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043586Testis-expressed 45.
Meox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043587Homeobox protein MOX-2; Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development. Activates expression of CDKN1A and CDKN2A in endothelial [...]
Crygs protein networkhttps://string-db.org/network/10090.ENSMUSP00000043588Gamma-crystallin S; Crystallins are the dominant structural components of the vertebrate eye lens.
Trpa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043594Transient receptor potential cation channel subfamily A member 1; Receptor-activated non-selective cation channel involved in pain detection and possibly also in cold perception, oxygen concentra [...]
Cdhr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043596Cadherin-related family member 2; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, [...]
Fa2h protein networkhttps://string-db.org/network/10090.ENSMUSP00000043597Fatty acid 2-hydroxylase; Catalyzes the hydroxylation of free fatty acids at the C-2 position to produce 2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids c [...]
Kin protein networkhttps://string-db.org/network/10090.ENSMUSP00000043614DNA/RNA-binding protein KIN17; Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and re [...]
Lmx1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000043616LIM homeobox transcription factor 1-beta; Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.
Rprd1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000043618Regulation of nuclear pre-mRNA domain-containing protein 1A; Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and partici [...]
Akap7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043624A-kinase anchor protein 7 isoform gamma; Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial [...]
Tmem132d protein networkhttps://string-db.org/network/10090.ENSMUSP00000043633Transmembrane protein 132D; May serve as a cell-surface marker for oligodendrocyte differentiation.
Galnt18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043636Polypeptide N-acetylgalactosaminyltransferase 18; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threo [...]
Bahcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043643BAH and coiled-coil domain-containing protein 1.
Tmem59l protein networkhttps://string-db.org/network/10090.ENSMUSP00000043659Transmembrane protein 59-like; Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further [...]
Sf3b6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043662Splicing factor 3B subunit 6; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U [...]
Scx protein networkhttps://string-db.org/network/10090.ENSMUSP00000043668Basic helix-loop-helix transcription factor scleraxis; Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages.
Dicer1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043676Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs an [...]
Gsap protein networkhttps://string-db.org/network/10090.ENSMUSP00000043679Gamma-secretase-activating protein 16 kDa C-terminal form; Regulator of gamma-secretase activity, which specifically activates the production of amyloid-beta protein (amyloid-beta protein 40 and [...]
Fbrs protein networkhttps://string-db.org/network/10090.ENSMUSP00000043682Probable fibrosin-1.
Atad2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043691ATPase family AAA domain-containing protein 2; May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as C [...]
Ptk7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043703Inactive tyrosine-protein kinase 7; Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the [...]
Cmtm8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043706CKLF-like MARVEL transmembrane domain-containing protein 8.
Dip2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000043710Disco-interacting protein 2 homolog A; May provide positional cues for axon pathfinding and patterning in the central nervous system; Belongs to the DIP2 family.
Pramel1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043718Preferentially expressed antigen in melanoma-like protein 1; May play a role in acrosome development and also in sperm maturation and motility; Belongs to the PRAME family.
Rcsd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043724CapZ-interacting protein; Stress-induced phosphorylation of CAPZIP may regulate the ability of F-actin-capping protein to remodel actin filament assembly.
Dph5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043730Diphthine methyl ester synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 ( [...]
Taf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043733Transcription initiation factor TFIID subunit 2; Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeri [...]
H2ap protein networkhttps://string-db.org/network/10090.ENSMUSP00000043734Huntingtin-interacting protein M.
Tmed8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043742Protein TMED8.
Ttll7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043753Tubulin polyglutamylase TTLL7; Polyglutamylase which preferentially modifies beta-tubulin. Mediates both ATP- dependent initiation and elongation of polyglutamylation of microtubules. Required fo [...]
Ephx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043764Epoxide hydrolase 4.
Cd81 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043768CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential [...]
Rfwd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043780E3 ubiquitin-protein ligase RFWD3; E3 ubiquitin-protein ligase required for the repair of DNA interstrand cross-links (ICL) in response to DNA damage. Plays a key role in RPA-mediated DNA damage [...]
Resp18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043783Regulated endocrine-specific protein 18; May play an important regulatory role in corticotrophs; Belongs to the RESP18 family.
Mks1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043790Meckel syndrome type 1 protein homolog; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of tran [...]
Camta2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043792Calmodulin-binding transcription activator 2; Transcription activator. May act as tumor suppressor (By similarity); Belongs to the CAMTA family.
1700034J05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000043802Uncharacterized protein C12orf71 homolog.
Melk protein networkhttps://string-db.org/network/10090.ENSMUSP00000043806Maternal embryonic leucine zipper kinase; Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulatio [...]
Col27a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043816Collagen alpha-1(XXVII) chain; Plays a role during the calcification of cartilage and the transition of cartilage to bone.
Lrrn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043818Leucine-rich repeat neuronal protein 3.
Aldh4a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043821Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a n [...]
Pnpla3 protein networkhttps://string-db.org/network/10090.ENSMUSP000000438261-acylglycerol-3-phosphate O-acyltransferase Pnpla3; Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosph [...]
Havcr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043827Hepatitis A virus cellular receptor 1 homolog; May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injur [...]
Hdac11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043828Histone deacetylase 11; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic re [...]
Itln1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043837Intelectin-1a; Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, includi [...]
Zyg11b protein networkhttps://string-db.org/network/10090.ENSMUSP00000043844Protein zyg-11 homolog B; Serves as substrate adapter subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC. Acts redudantly with ZER1 to target substrates bearing N-terminal glycine [...]
Mtmr7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043851Myotubularin-related protein 7; Phosphatase that specifically dephosphorylates phosphatidylinositol 3-phosphate (PtdIns(3)P) and inositol 1,3- bisphosphate (Ins(1,3)P2); Belongs to the protein-ty [...]
Tmc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043853Transmembrane channel-like protein 4; Probable ion channel; Belongs to the TMC family.
Ubash3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000043865Ubiquitin-associated and SH3 domain-containing protein B; Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target [...]
Kmt2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000043874Histone-lysine N-methyltransferase 2C; Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Cen [...]
Mrap protein networkhttps://string-db.org/network/10090.ENSMUSP00000043890Melanocortin-2 receptor accessory protein; Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing gen [...]
Chtf18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043896Chromosome transmission fidelity protein 18 homolog; Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear [...]
Mcrs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043901Microspherule protein 1; Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal hist [...]
Lcn8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043902Epididymal-specific lipocalin-8; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis.
Nfya protein networkhttps://string-db.org/network/10090.ENSMUSP00000043909Nuclear transcription factor Y subunit alpha; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the prom [...]
Bace2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043918Beta-secretase 2; Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release [...]
Pnp protein networkhttps://string-db.org/network/10090.ENSMUSP00000043926Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formati [...]
Tango6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043953Transport and Golgi organization protein 6 homolog; Belongs to the Tango6 family.
Iapp protein networkhttps://string-db.org/network/10090.ENSMUSP00000043956Islet amyloid polypeptide; Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism; Belongs to the calciton [...]
Lama1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043957Laminin subunit alpha-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development [...]
Fam90a1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000043958Family with sequence similarity 90, member A1B.
Slc2a12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043962Solute carrier family 2, facilitated glucose transporter member 12; Insulin-independent facilitative glucose transporter.
Arsi protein networkhttps://string-db.org/network/10090.ENSMUSP00000043966Arylsulfatase I; Displays arylsulfatase activity at neutral pH, when co- expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is [...]
Nop53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043981Ribosome biogenesis protein NOP53; Nucleolar protein which is involved in the integration of the 5S RNP into the ribosomal large subunit during ribosome biogenesis. In ribosome biogenesis, may al [...]
Ap1g2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000043996AP-1 complex subunit gamma-like 2; May function in protein sorting in late endosomes or multivesucular bodies (MVBs). Involved in MVB-assisted maturation of hepatitis B virus (HBV); Belongs to th [...]
Vstm2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000044002V-set and transmembrane domain-containing protein 2B.
Lrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044004Low-density lipoprotein receptor-related protein 1 intracellular domain; Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic developmen [...]
Grid1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044009Glutamate receptor ionotropic, delta-1; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu [...]
Agl protein networkhttps://string-db.org/network/10090.ENSMUSP00000044012Amylo-1,6-glucosidase, 4-alpha-glucanotransferase.
2610008E11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000044020RIKEN cDNA 2610008E11 gene.
Ovol2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044026Transcription factor Ovo-like 2; Zinc-finger transcription repressor factor. Plays a critical role in maintaining the identity of epithelial lineages by suppressing epithelial-to mesenchymal tran [...]
Spertl protein networkhttps://string-db.org/network/10090.ENSMUSP00000044028Spermatid-associated-like.
Serpina6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044033Corticosteroid-binding globulin; Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species; Belongs to the serpin family.
Gadd45a protein networkhttps://string-db.org/network/10090.ENSMUSP00000044034Growth arrest and DNA damage-inducible protein GADD45 alpha; Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhi [...]
L3mbtl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044038Lethal(3)malignant brain tumor-like protein 1; Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader [...]
Padi6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044044Protein-arginine deiminase type-6; Catalyzes the deimination of arginine residues of proteins (By similarity). May be involved in cytoskeletal reorganization in the egg and early embryo.
Mcl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044048Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Me [...]
Tubgcp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044049Gamma-tubulin complex component 4; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Dpp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044050Dipeptidyl peptidase 4 membrane form; Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation. Acts as a positive r [...]
Lhfpl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044054LHFPL tetraspan subfamily member 1 protein; Belongs to the LHFP family.
Zfc3h1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044069Zinc finger, C3H1-type-containing.
Hpse protein networkhttps://string-db.org/network/10090.ENSMUSP00000044072Heparanase 50 kDa subunit; Endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) d [...]
Pus7l protein networkhttps://string-db.org/network/10090.ENSMUSP00000044075Pseudouridylate synthase 7 homolog-like protein; Pseudouridylate synthase that catalyzes pseudouridylation of RNAs; Belongs to the pseudouridine synthase TruD family.
Pnpla7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044078Patatin-like phospholipase domain-containing protein 7; Serine hydrolase, whose specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy (By similarity [...]
Ccdc81 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044087Coiled-coil domain-containing protein 81.
Tas2r108 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044089Taste receptor type 2 member 4; Gustducin-coupled receptor for denatonium and N(6)-propyl-2- thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestina [...]
Cyb561d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044093Cytochrome b561 domain-containing protein 2; Two-heme-containing cytochrome that catalyzes ascorbate- dependent trans-membrane ferric-chelate reduction.
Styk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044098Tyrosine-protein kinase STYK1; Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines including NIH 3T3 fibroblasts and on athymic nude mice. When [...]
Tmem156 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044102Transmembrane protein 156.
Mettl22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044108Methyltransferase-like protein 22; Protein N-lysine methyltransferase. In vitro methylates KIN (By similarity).
Siah1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000044123E3 ubiquitin-protein ligase SIAH1A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from [...]
Trir protein networkhttps://string-db.org/network/10090.ENSMUSP00000044129Telomerase RNA component interacting RNase; Exoribonuclease that is part of the telomerase RNA 3' end processing complex and which has the ability to all four unpaired RNA nucleotides from 5' end [...]
Abhd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044134(Lyso)-N-acylphosphatidylethanolamine lipase; Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N- acyl ethanolamines, including the endoc [...]
Mfhas1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044135Malignant fibrous histiocytoma-amplified sequence 1 homolog; Probable GTP-binding protein (By similarity). Functions in innate immunity and more specifically the inflammatory response as a regula [...]
Snx10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044165Sorting nexin-10; Probable phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes. Plays a role in cilium biogenesis through regulation of the transpor [...]
Leap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044166Liver-expressed antimicrobial peptide 2; Has an antimicrobial activity; Belongs to the LEAP2 family.
Otoa protein networkhttps://string-db.org/network/10090.ENSMUSP00000044177Otoancorin; May act as an adhesion molecule. Belongs to the stereocilin family.
Lsm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044178U6 snRNA-associated Sm-like protein LSm3; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatal [...]
Slc9a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044185Sodium/hydrogen exchanger 8; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by th [...]
Ptma protein networkhttps://string-db.org/network/10090.ENSMUSP00000044188Prothymosin alpha, N-terminally processed; Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections; Belongs to the pro/parathymosin family.
Pramel5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044222Preferentially-expressed antigen in melanoma-like 5.
Itga9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044227Integrin alpha-9; Integrin alpha-9/beta-1 (ITGA9:ITGB1) is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D- G-I-E-L in cytotactin.
Naaladl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044231Aminopeptidase NAALADL1; Aminopeptidase with broad substrate specificity. Has lower activity with substrates that have Asp or Glu in the P2' position, or Pro in the P3' position. Lacks activity w [...]
Prdm14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044245PR domain zinc finger protein 14; Transcription factor that has both positive and negative roles on transcription (By similarity). Plays a role in cellular pluripotency. Essential for germ cell d [...]
Scarf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044248Scavenger receptor class F member 1; Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion pro [...]
Stpg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044250Protein STPG4; Maternal factor that plays a role in epigenetic chromatin reprogramming during early development of the zygote. Involved in the regulation of gametic DNA demethylation by inducing [...]
Chchd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044253Coiled-coil-helix-coiled-coil-helix domain-containing protein 5.
Ap4b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044262AP-4 complex subunit beta-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They [...]
0610010F05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000044265Uncharacterized protein KIAA1841.
Med13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044268Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Sh3pxd2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000044276SH3 and PX domain-containing protein 2B; Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidas [...]
Pcyt1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000044280Choline-phosphate cytidylyltransferase B; Controls phosphatidylcholine synthesis. Belongs to the cytidylyltransferase family.
Nubpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000044292Iron-sulfur protein NUBPL; Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). May deliver of one or more Fe-S clusters to complex I subunits [...]
Cdc40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044305Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome.
Slco1b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044326Solute carrier organic anion transporter family member 1B2; Mediates the Na(+)-independent uptake of organic anions such as taurochlate, bromosulfophthalein and steroid conjugates such as estrone [...]
Lgalsl protein networkhttps://string-db.org/network/10090.ENSMUSP00000044342Galectin-related protein; Does not bind lactose, and may not bind carbohydrates.
Azi2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000443505-azacytidine-induced protein 2; Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligome [...]
Pmch protein networkhttps://string-db.org/network/10090.ENSMUSP00000044352Neuropeptide-glutamic acid-isoleucine; MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as [...]
1700031F05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000044360RIKEN cDNA 1700031F05 gene.
Smarca5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044361SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5; Helicase that possesses intrinsic ATP-dependent nucleosome- remodeling activity. Complexes containin [...]
Recql4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044363ATP-dependent DNA helicase Q4; DNA-dependent ATPase (By similarity). May play a role in development of the palate and the limbs. May modulate chromosome segregation.
Pygo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044368Pygopus homolog 1; Involved in signal transduction through the Wnt pathway.
Hsdl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044371Inactive hydroxysteroid dehydrogenase-like protein 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
Pacrg protein networkhttps://string-db.org/network/10090.ENSMUSP00000044376Parkin coregulated gene protein homolog; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consistin [...]
Snx22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044389Sorting nexin 22.
H1f3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044395Histone H1.3; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucle [...]
Plk5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044400Inactive serine/threonine-protein kinase PLK5; Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.
Fmo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044405Dimethylaniline monooxygenase [N-oxide-forming] 2; This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Shows catalytic activity towards [...]
Cpne9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044416Copine-9; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes. Plays a role in dendrite formation by melanocytes.
Mrpl12 protein networkhttps://string-db.org/network/10090.ENSMUSP0000004441739S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family.
Spns2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044418Protein spinster homolog 2; Acts a a crucial lysosphingolipid sphingosine 1-phosphate (S1P) transporter involved in S1P secretion and function. S1P is a bioactive signaling molecule that regulate [...]
Cdv3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044420Protein CDV3; Belongs to the CDV3 family.
Meak7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044430MTOR-associated protein MEAK7; Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration. Recruits MTOR at the lysoso [...]
Zgrf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044432Protein ZGRF1.
Slfn9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044435Schlafen family member 9; Endoribonuclease that cleaves tRNAs and rRNAs. Belongs to the Schlafen family. Subgroup III subfamily.
Dop1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000044437Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes.
Csdc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044441Cold shock domain-containing protein C2; RNA-binding factor which binds specifically to the very 3'- UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might pla [...]
Sdr42e1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044457Short-chain dehydrogenase/reductase family 42E member 1.
Scaf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044472SR-related and CTD-associated factor 4; Anti-terminator protein required to prevent early mRNA termination during transcription. Together with SCAF8, acts by suppressing the use of early, alterna [...]
Trem3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044478Triggering receptor expressed on myeloid cells 3; Forms a receptor signaling complex with TYROBP/DAP12 which mediates activation of macrophages as part of the innate immune response.
Trak1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044482Trafficking kinesin-binding protein 1; Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors (By similarity). [...]
Stard8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044491StAR-related lipid transfer protein 8; Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5-bisphosphate by PLCD1 (By similarity).
Tmem71 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044493Transmembrane protein 71.
Gria1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044494Glutamate receptor 1; Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter [...]
Mrpl34 protein networkhttps://string-db.org/network/10090.ENSMUSP0000004449739S ribosomal protein L34, mitochondrial; Belongs to the bacterial ribosomal protein bL34 family.
Efhd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044502EF-hand domain-containing protein D2; May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating b [...]
Gzmk protein networkhttps://string-db.org/network/10090.ENSMUSP00000044512Granzyme K.
Tsc22d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044517TSC22 domain family protein 1; Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter; Belongs to the TSC-22/Dip/Bun family.
Gucy2f protein networkhttps://string-db.org/network/10090.ENSMUSP00000044521Retinal guanylyl cyclase 2; Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors (By similarity). Plays an essential role in phototransduction, by mediating cGMP [...]
Zbed5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044533Zinc finger, BED type-containing 5.
Fermt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044554Fermitin family homolog 2; Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosph [...]
Kctd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044568BTB/POZ domain-containing protein KCTD7; May be involved in the control of excitability of cortical neurons.
R3hdm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044570R3H domain-containing protein 4.
Tbc1d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044577TBC1 domain family member 1; May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the traffickin [...]
Arrdc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044578Arrestin domain-containing protein 4; Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates. Plays a role in endocytosis of activated G protein-coupled recepto [...]
Ttbk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044580Tau-tubulin kinase 1; Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU (By similarity); Belongs to the protein kin [...]
Polr3k protein networkhttps://string-db.org/network/10090.ENSMUSP00000044582DNA-directed RNA polymerase III subunit RPC10; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA [...]
Nat8f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044587N-acetyltransferase family 8 member 2; Probable acetyltransferase (Probable). Has no detectable histone acetyltransferase activity towards histone H3 or H4. Belongs to the camello family.
Pim3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044603Serine/threonine-protein kinase pim-3; Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis and promote cell survival and protein translation. May contribute to tumorig [...]
Aaas protein networkhttps://string-db.org/network/10090.ENSMUSP00000044604Aladin; Plays a role in the normal development of the peripheral and central nervous system. Required for the correct localization of aurora kinase AURKA and the microtubule minus end-binding pro [...]
Enpp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044608Glycerophosphocholine cholinephosphodiesterase ENPP6; Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to su [...]
Wdr44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044616WD repeat-containing protein 44; Downstream effector for RAB11. May be involved in vesicle recycling (By similarity).
Arhgap29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044624Rho GTPase-activating protein 29; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and [...]
Dtx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044627Probable E3 ubiquitin-protein ligase DTX3; Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Prob [...]
Lad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044630Ladinin-1; Anchoring filament protein which is a component of the basement membrane zone.
Asb11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044637Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquit [...]
Rhot2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044639Mitochondrial Rho GTPase 2; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (B [...]
Smc1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000044645Structural maintenance of chromosomes protein 1A; Involved in chromosome cohesion during cell cycle and in DNA repair. Involved in DNA repair via its interaction with BRCA1 and its related phosph [...]
Cd3eap protein networkhttps://string-db.org/network/10090.ENSMUSP00000044653DNA-directed RNA polymerase I subunit RPA34; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
Cacna2d4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044660Voltage-dependent calcium channel subunit alpha-2/delta-4; The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics o [...]
Crp protein networkhttps://string-db.org/network/10090.ENSMUSP00000044665C-reactive protein; Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-depen [...]
Fbxo34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044675F-box only protein 34; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Thoc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044677THO complex subunit 2; Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcript [...]
Psenen protein networkhttps://string-db.org/network/10090.ENSMUSP00000044682Gamma-secretase subunit PEN-2; Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch rece [...]
Trmt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044687tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)-methyladenine at [...]
Palmd protein networkhttps://string-db.org/network/10090.ENSMUSP00000044693Palmdelphin; Belongs to the paralemmin family.
Cip2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000044714Protein CIP2A; Promotes anchorage-independent cell growth and tumor formation.
Nmur2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044718Neuromedin-U receptor 2; Receptor for the neuromedin-U and neuromedin-S neuropeptides.
Cyp2c38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044722Cytochrome P450 2C38; Metabolizes arachidonic acid to produce 11,12- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family.
Bag4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044725BAG family molecular chaperone regulator 4; Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Prevents constitutive TNFRSF1A signaling (By similarity). Negative regul [...]
P2ry13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044730P2Y purinoceptor 13; Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system (By similarity).
Fam102a protein networkhttps://string-db.org/network/10090.ENSMUSP00000044731Protein FAM102A; May play a role in estrogen action.
Zdhhc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044734Palmitoyltransferase ZDHHC9; The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.
Tmem258 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044751Transmembrane protein 258; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid car [...]
Tcam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044757Testicular cell adhesion molecule 1.
Ifi44l protein networkhttps://string-db.org/network/10090.ENSMUSP00000044765Minor histocompatibility antigen HA-28; Precursor of the histocompatibility antigen HA-28 in BALB.B mice. More generally, minor histocompatibility antigens refer to immunogenic peptide which, whe [...]
Atg5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044769Autophagy protein 5; Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E [...]
Cog5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044797Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function.
Herc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044801HECT and RLD domain-containing E3 ubiquitin protein ligase family member 1.
Efcab11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044808EF-hand calcium-binding domain-containing protein 11.
Mucl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044814Mucin-like protein 2.
Suco protein networkhttps://string-db.org/network/10090.ENSMUSP00000044815SUN domain-containing ossification factor; Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation.
Mybbp1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000044827Myb-binding protein 1A; May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase acti [...]
Atrip protein networkhttps://string-db.org/network/10090.ENSMUSP00000044831ATR-interacting protein; Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein (By similarity); Belongs to the ATRIP family.
Bicral protein networkhttps://string-db.org/network/10090.ENSMUSP00000044833BRD4-interacting chromatin-remodeling complex-associated protein-like; Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin stru [...]
Arhgap18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044834Rho GTPase-activating protein 18; Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an i [...]
Tut4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044836Terminal uridylyltransferase 4; Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay. Esse [...]
2410137M14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000044846RIKEN cDNA 2410137M14 gene.
Crtac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044858Cartilage acidic protein 1.
A930018P22Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000044861Uncharacterized protein C11orf91 homolog.
Sos2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044866Son of sevenless homolog 2; Promotes the exchange of Ras-bound GDP by GTP.
Pigs protein networkhttps://string-db.org/network/10090.ENSMUSP00000044871GPI transamidase component PIG-S; Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates (By similarity); Belon [...]
Bet1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044877BET1 homolog; Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER- derived vesicles with the cis-Golgi membrane (By simil [...]
Isl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044879Insulin gene enhancer protein ISL-1; DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamen [...]
Scaf11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044898SR-related CTD-associated factor 11.
Thbs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044903Thrombospondin-1; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp. [...]
Zswim2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044913E3 ubiquitin-protein ligase Zswim2; E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 [...]
Inhbb protein networkhttps://string-db.org/network/10090.ENSMUSP00000044918Inhibin beta B chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diver [...]
Dhrs7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000044924Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase.
Tmem35a protein networkhttps://string-db.org/network/10090.ENSMUSP00000044926Transmembrane protein 35A; A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth.
Fanci protein networkhttps://string-db.org/network/10090.ENSMUSP00000044931Fanconi anemia group I protein homolog; Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by pr [...]
Cct8l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044932Chaperonin-containing TCP1, subunit 8 (theta)-like 1.
Txlnb protein networkhttps://string-db.org/network/10090.ENSMUSP00000044936Beta-taxilin; Promotes motor nerve regeneration. May be involved in intracellular vesicle traffic (By similarity).
Nars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044937Probable asparagine--tRNA ligase, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family.
Mitf protein networkhttps://string-db.org/network/10090.ENSMUSP00000044938Microphthalmia-associated transcription factor; Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to M-bo [...]
Cryzl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044945Quinone oxidoreductase-like protein 2.
Hacd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044955Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, [...]
Cavin3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044979Caveolae-associated protein 3; Regulates the traffic and/or budding of caveolae (By similarity). Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveo [...]
Hand2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044983Heart- and neural crest derivatives-expressed protein 2; Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for v [...]
Phf12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044990PHD finger protein 12; Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an assoc [...]
Lsm7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000044993U6 snRNA-associated Sm-like protein LSm7; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatal [...]
Rptn protein networkhttps://string-db.org/network/10090.ENSMUSP00000044998Repetin; Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein; Belongs to the S100-fused protein family.
Lime1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045010Lck-interacting transmembrane adapter 1; Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T-cell signaling in T-cells. In absence [...]
Cog3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045016Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.
Slco4a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045023Solute carrier organic anion transporter family member 4A1; Mediates the Na(+)-independent transport of organic anions such as the thyroid hormone T3 (triiodo-L-thyronine) and of taurocholate.
Fam151b protein networkhttps://string-db.org/network/10090.ENSMUSP00000045024Family with sequence similarity 151, member B.
Tgtp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045025T-cell-specific guanine nucleotide triphosphate-binding protein 1; Involved in innate cell-autonomous resistance to intracellular pathogens, such as Toxoplasma gondii. During avirulent type II T. [...]
Myof protein networkhttps://string-db.org/network/10090.ENSMUSP00000045036Myoferlin; Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress [...]
Dnttip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045043Deoxynucleotidyltransferase terminal-interacting protein 2; Regulates the transcriptional activity of DNTT and ESR1. May function as a chromatin remodeling protein (By similarity).
Tcta protein networkhttps://string-db.org/network/10090.ENSMUSP00000045063T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.
Sf3b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045073Splicing factor 3B subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly [...]
Nlrp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045077NLR family, pyrin domain-containing 2.
Fam160a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045084FTS and Hook-interacting protein; Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular prote [...]
Mon1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000045089Vacuolar fusion protein MON1 homolog B.
E330009J07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000045103DENN domain-containing protein 11; Probable guanine nucleotide exchange factor (GEF). May promote the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bou [...]
Ppp1r14c protein networkhttps://string-db.org/network/10090.ENSMUSP00000045110Protein phosphatase 1 regulatory subunit 14C; Inhibitor of the PP1 regulatory subunit PPP1CA.
Mrps34 protein networkhttps://string-db.org/network/10090.ENSMUSP0000004511128S ribosomal protein S34, mitochondrial; Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for m [...]
Prss40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045118Serine protease 40; May play an important role in the sperm/egg interaction; released during the acrosome reaction; Belongs to the peptidase S1 family.
S100g protein networkhttps://string-db.org/network/10090.ENSMUSP00000045120Protein S100-G; Belongs to the S-100 family.
Hmgxb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045126HMG box domain-containing 4.
Ackr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045134Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal [...]
Trp53rka protein networkhttps://string-db.org/network/10090.ENSMUSP00000045141Transformation-related protein 53-regulating kinase A.
Islr protein networkhttps://string-db.org/network/10090.ENSMUSP00000045142Immunoglobulin superfamily containing leucine-rich repeat protein.
Slc10a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045150P3 protein; The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions; Belongs to the bile aci [...]
Tmx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045154Thioredoxin-related transmembrane protein 4.
Zfhx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045156Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli.
Acsm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045160Acyl-coenzyme A synthetase ACSM4, mitochondrial; Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (By similarity). Capable of activat [...]
Vasn protein networkhttps://string-db.org/network/10090.ENSMUSP00000045162Vasorin; May act as an inhibitor of TGF-beta signaling.
Prss23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045191Serine protease 23.
Muc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045196Mucin 3, intestinal.
Sun3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045199SUN domain-containing protein 3; As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleto [...]
Neil2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045200Endonuclease 8-like 2; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5- hydroxyuracil and other oxidized derivatives of [...]
Wipi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045201WD repeat domain phosphoinositide-interacting protein 2; Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged [...]
Uchl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045208Ubiquitin carboxyl-terminal hydrolase isozyme L4; Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol prot [...]
Ano10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045214Anoctamin-10; Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1 (By similarity). Belongs to the anoctamin family.
Slc16a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045216Monocarboxylate transporter 1; Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-ch [...]
Fanca protein networkhttps://string-db.org/network/10090.ENSMUSP00000045217Fanconi anemia group A protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair a [...]
Svs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045221Amine oxidase; Belongs to the copper/topaquinone oxidase family.
Neu3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045222Sialidase-3; Plays a role in modulating the ganglioside content of the lipid bilayer at the level of membrane-bound sialyl glycoconjugates. Belongs to the glycosyl hydrolase 33 family.
Sec1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045229Galactoside 2-alpha-L-fucosyltransferase 3; Belongs to the glycosyltransferase 11 family.
Catsperg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045233Cation channel sperm-associated protein subunit gamma 1; Belongs to the CATSPERG family.
Golgb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045239Golgi autoantigen, golgin subfamily b, macrogolgin 1.
Oscp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045241Protein OSCP1; May be involved in drug clearance in the placenta.
Tmem120a protein networkhttps://string-db.org/network/10090.ENSMUSP00000045252Transmembrane protein 120A; Necessary for efficient adipogenesis.
Oma1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045269Metalloendopeptidase OMA1, mitochondrial; Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitocho [...]
Alg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045272Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man5GlcNAc2-PP-Dol; Belongs to the glycosyltransferase 58 famil [...]
Pbx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045281Pre-B-cell leukemia transcription factor 3; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'; Belongs to the TALE/PBX homeobox family.
Tspan33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045282Tetraspanin-33; Plays an important role in normal erythropoiesis. It has a role in the differentiation of erythroid progenitors. Regulates maturation and trafficking of the transmembrane metallop [...]
Dnph1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000452832'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine [...]
Uqcrfs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045284Cytochrome b-c1 complex subunit Rieske, mitochondrial; [Cytochrome b-c1 complex subunit Rieske, mitochondrial]: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembran [...]
Abca3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045285ATP-binding cassette sub-family A member 3; Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol.
Spag5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045286Sperm-associated antigen 5; Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing o [...]
4930505A04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000045288Uncharacterized protein C2orf73 homolog.
Acsl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045291Long-chain-fatty-acid--CoA ligase 3; Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta- oxidation (By similarity). ACSL3 [...]
Uvrag protein networkhttps://string-db.org/network/10090.ENSMUSP00000045297UV radiation resistance-associated protein; Versatile protein that is involved in regulation of different cellular pathways implicated in membrane trafficking. Involved in regulation of the COPI- [...]
Prkx protein networkhttps://string-db.org/network/10090.ENSMUSP00000045304cAMP-dependent protein kinase catalytic subunit PRKX; Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that m [...]
Mfsd2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000045315Major facilitator superfamily domain-containing protein 2B; Cation-dependent lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets. Sphin [...]
Gjb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045325Gap junction beta-5 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a [...]
Crygd protein networkhttps://string-db.org/network/10090.ENSMUSP00000045327Gamma-crystallin D; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family.
Itprid1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045332Protein ITPRID1.
Pcdh8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045333Protocadherin-8; Calcium-dependent cell-adhesion protein (By similarity). May play a role in activity-induced synaptic reorganization underlying long term memory (By similarity). Could be involve [...]
Bdkrb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045335B1 bradykinin receptor; This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation; Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. B [...]
AAdacl4fm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045343AADACL4 family member 3.
Clspn protein networkhttps://string-db.org/network/10090.ENSMUSP00000045344Claspin; Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation. Adapter protein which binds [...]
Chst11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045349Carbohydrate sulfotransferase 11; Catalyzes the transfer of sulfate to position 4 of the N- acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant pr [...]
Pigk protein networkhttps://string-db.org/network/10090.ENSMUSP00000045351GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidatio [...]
Nat14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045354N-acetyltransferase 14; Probable acetyltransferase that binds the 5'-GGACTACAG-3' sequence of coproporphyrinogen oxidase promoter. Able to activate transcription of a reporter construct in vitro [...]
Limd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045357LIM domain-containing protein 2; Acts as an activator of the protein-kinase ILK, thereby regulating cell motility.
Parl protein networkhttps://string-db.org/network/10090.ENSMUSP00000045361Presenilins-associated rhomboid-like protein, mitochondrial; Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 w [...]
Cyp2c37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045362Cytochrome P450 2C37; Metabolizes arachidonic acid to produce 12- hydroxyeicosatetraenoic acid (HETE); Belongs to the cytochrome P450 family.
Zmym6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045366Zinc finger, MYM-type 6.
Dennd2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000045367DENN domain-containing protein 2A; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins int [...]
Ndn protein networkhttps://string-db.org/network/10090.ENSMUSP00000045369Necdin; Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-pr [...]
2410004B18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000045376UPF0690 protein C1orf52 homolog; Belongs to the UPF0690 family.
Shfl protein networkhttps://string-db.org/network/10090.ENSMUSP00000045384Shiftless antiviral inhibitor of ribosomal frameshifting protein homolog; Inhibits programmed -1 ribosomal frameshifting (-1PRF) of a variety of mRNAs from viruses and cellular genes. Interacts w [...]
Igdcc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045387Immunoglobulin superfamily DCC subclass member 4; Belongs to the immunoglobulin superfamily. DCC family.
Ogt protein networkhttps://string-db.org/network/10090.ENSMUSP00000045409UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytopl [...]
Tbc1d2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000045413TBC1 domain family member 2B; May act as a GTPase-activating protein.
Catsper1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045430Cation channel sperm-associated protein 1; Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a [...]
Mamdc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045432MAM domain-containing protein 2.
Acp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045437Acid phosphatase type 7; Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.
Mboat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045441Lysophospholipid acyltransferase 1; Acyltransferase which mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1 [...]
Zp3r protein networkhttps://string-db.org/network/10090.ENSMUSP00000045443Zona pellucida sperm-binding protein 3 receptor; Binds to ZP3 glycoprotein in egg zona pellucida. Probably involved in interactions between sperm acrosome and egg zona pellucida during and immedi [...]
Mllt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045445Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6.
Adgb protein networkhttps://string-db.org/network/10090.ENSMUSP00000045452Androglobin; Belongs to the peptidase C2 family.
Rad54l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045454Helicase ARIP4; DNA helicase that modulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. Not able to remodel mononucleosomes in vitro. Acts as an AR-coregulato [...]
Ssr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045456Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
Psme4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045460Proteasome activator complex subunit 4; Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin- independent degradation of core hi [...]
Pnliprp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045465Inactive pancreatic lipase-related protein 1; May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity (in vitro) (By similarity).
Ift122 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045468Intraflagellar transport protein 122 homolog; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors [...]
Atg101 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045474Autophagy-related protein 101; Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.
Lzts2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045478Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion [...]
Dync1li2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045480Cytoplasmic dynein 1 light intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to [...]
4930544G11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000045487RIKEN cDNA 4930544G11 gene.
Vps13b protein networkhttps://string-db.org/network/10090.ENSMUSP00000045490Vacuolar protein sorting-associated protein 13B; May be involved in protein sorting in post Golgi membrane traffic; Belongs to the VPS13 family.
Rbm46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045511Probable RNA-binding protein 46.
Defb7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045523Beta-defensin 7; Has bactericidal activity; Belongs to the beta-defensin family. LAP/TAP subfamily.
Cdk10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045527Cyclin-dependent kinase 10; Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells). Involved in the re [...]
Npy1r protein networkhttps://string-db.org/network/10090.ENSMUSP00000045530Neuropeptide Y receptor type 1; Receptor for neuropeptide Y and peptide YY.
Fam53a protein networkhttps://string-db.org/network/10090.ENSMUSP00000045539Protein FAM53A; May play an important role in neural development; the dorsomedial roof of the third ventricle. Belongs to the FAM53 family.
Tspyl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045542Testis-specific Y-encoded-like protein 5; Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulati [...]
Fam199x protein networkhttps://string-db.org/network/10090.ENSMUSP00000045544Protein FAM199X; Belongs to the FAM199 family.
Zfp410 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045550Zinc finger protein 410; Transcription factor that activates transcription of matrix- remodeling genes such as MMP1 during fibroblast senescence.
Ints9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045552Integrator complex subunit 9; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The [...]
Clcf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045562Cardiotrophin-like cytokine factor 1; In complex with CRLF1, forms a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development (By similarity). Also stimulates B-ce [...]
Rubcnl protein networkhttps://string-db.org/network/10090.ENSMUSP00000045566Protein associated with UVRAG as autophagy enhancer; Regulator of autophagy that promotes autophagosome maturation by facilitating the biogenesis of phosphatidylinositol 3-phosphate (PtdIns(3)P) [...]
Zbtb41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045570Zinc finger and BTB domain-containing protein 41; May be involved in transcriptional regulation.
Serpina12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045572Serpin A12; Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues.
Lce1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000045573Late cornified envelope 1C.
Thoc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045580THO complex subunit 5 homolog; Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically ass [...]
Asic4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045598Acid-sensing ion channel 4; Probable cation channel with high affinity for sodium; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC4 subfamily.
Hibch protein networkhttps://string-db.org/network/10090.ENSMUSP000000456063-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrog [...]
Nbl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045608Neuroblastoma suppressor of tumorigenicity 1; Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) o [...]
Slc36a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045613Proton-coupled amino acid transporter 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids amino acids such as glycine, alanine and proline. Inhibi [...]
Decr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045621Peroxisomal 2,4-dienoyl-CoA reductase; Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered [...]
A4gnt protein networkhttps://string-db.org/network/10090.ENSMUSP00000045629Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically [...]
Antxr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045634Anthrax toxin receptor 1; Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collage [...]
Rims4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045637Regulating synaptic membrane exocytosis protein 4; Regulates synaptic membrane exocytosis.
Klf9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045639Krueppel-like factor 9; Transcription factor that binds to GC box promoter elements. Selectively activates mRNA synthesis from genes containing tandem repeats of GC boxes but represses genes with [...]
Ybey protein networkhttps://string-db.org/network/10090.ENSMUSP00000045647Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in rRNA maturation; Belongs to the endoribonuclease YbeY family.
Tm7sf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045650Transmembrane 7 superfamily member 3; Involved in the inhibition of cytokine-induced death of pancreatic beta cells. Involved in the promotion of insulin secretion from pancreatic beta cells (By [...]
Fancd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045667Fanconi anemia group D2 protein homolog; Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA doubl [...]
Ushbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045668Usher syndrome type-1C protein-binding protein 1.
Prss34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045672Mast cell protease-11; Belongs to the peptidase S1 family.
Pkd2l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045675Polycystic kidney disease 2-like 1 protein; Pore-forming subunit of a heteromeric, non-selective cation channel that is permeable to Ca(2+). Pore-forming subunit of a calcium-permeant ion channel [...]
Gmip protein networkhttps://string-db.org/network/10090.ENSMUSP00000045676GEM-interacting protein; Stimulates, in vitro and in vivo, the GTPase activity of RhoA.
Gm17018 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045683Protein DPCD; May play a role in the formation or function of ciliated cells; Belongs to the DPCD family.
Zfp51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045684Zinc finger protein 51.
Cobl protein networkhttps://string-db.org/network/10090.ENSMUSP00000045693Protein cordon-bleu; Plays an important role in the reorganization of the actin cytoskeleton. Binds to and sequesters actin monomers (G actin). Nucleates actin polymerization by assembling three [...]
Pln protein networkhttps://string-db.org/network/10090.ENSMUSP00000045709Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of th [...]
Fgf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045710Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. [...]
Rgs8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045715Regulator of G-protein signaling 8; Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits s [...]
Galnt12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045721Polypeptide N-acetylgalactosaminyltransferase 12; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threo [...]
Fam222a protein networkhttps://string-db.org/network/10090.ENSMUSP00000045724Protein FAM222A; Belongs to the FAM222 family.
Secisbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045740SECIS-binding protein 2.
Batf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045744Basic leucine zipper transcriptional factor ATF-like 2; AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Selectively suppresses C [...]
Sectm1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000045748Secreted and transmembrane protein 1b; May be involved in thymocyte signaling.
Cpne2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045755Copine-2; Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Exhibits calcium- dependent cell membrane binding properties.
Tlr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045770Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, [...]
Fbxl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045792F-box/LRR-repeat protein 5; Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradati [...]
Ptpn7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045803Tyrosine-protein phosphatase non-receptor type 7; May play a role in the regulation of T and B-lymphocyte development and signal transduction; Belongs to the protein-tyrosine phosphatase family. [...]
Zfp174 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045805Zinc finger protein 174.
Phyhipl protein networkhttps://string-db.org/network/10090.ENSMUSP00000045807Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. Belongs to the PHYHIP family.
Abca8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000045808ATP-binding cassette sub-family A member 8-A; ATP-dependent lipophilic drug transporter.
Pwp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045812Periodic tryptophan protein 2 homolog.
H1f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045816Histone H1.2; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucle [...]
Spata7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045827Spermatogenesis-associated protein 7 homolog; Involved in the maintenance of both rod and cone photoreceptor cells. Required for photoreceptor-specific localization of proximal connecting cilium [...]
Mael protein networkhttps://string-db.org/network/10090.ENSMUSP00000045828Protein maelstrom homolog; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts v [...]
Dusp10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045838Dual specificity protein phosphatase 10; Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. It preferably dephosphor [...]
Eprs protein networkhttps://string-db.org/network/10090.ENSMUSP00000045841Bifunctional glutamate/proline--tRNA ligase; Multifunctional protein which is primarily part of the aminoacyl-tRNA synthetase multienzyme complex, also know as multisynthetase complex, that catal [...]
Svep1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045856Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1; May play a role in the cell attachment process.
Nceh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045864Neutral cholesterol ester hydrolase 1; Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsibl [...]
Anln protein networkhttps://string-db.org/network/10090.ENSMUSP00000045873Anillin; Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression. Plays a role in bleb assembly during metaphase a [...]
Abt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045888Activator of basal transcription 1; Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II g [...]
Tubg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045901Tubulin gamma-2 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentrio [...]
Inpp5f protein networkhttps://string-db.org/network/10090.ENSMUSP00000045910Phosphatidylinositide phosphatase SAC2; Inositol 4-phosphatase which mainly acts on phosphatidylinositol 4-phosphate. May be functionally linked to OCRL, which converts phosphatidylinositol 4,5-b [...]
Gpsm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045911G-protein-signaling modulator 3; Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins.
Iqce protein networkhttps://string-db.org/network/10090.ENSMUSP00000045913IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Required for proper limb morphogenesis (By similarity).
Fbxo15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045925F-box only protein 15; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Fam210a protein networkhttps://string-db.org/network/10090.ENSMUSP00000045927Protein FAM210A; May play a role in the structure and strength of both muscle and bone.
Ppig protein networkhttps://string-db.org/network/10090.ENSMUSP00000045945Peptidyl-prolyl cis-trans isomerase G; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. May be implicat [...]
Noa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045948Nitric oxide-associated protein 1; Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein [...]
Sec24c protein networkhttps://string-db.org/network/10090.ENSMUSP00000045955Sec24-related gene family, member C (S. cerevisiae).
Six5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045973Homeobox protein SIX5; Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCA [...]
Nemp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000045988Nuclear envelope integral membrane protein 1.
Mycn protein networkhttps://string-db.org/network/10090.ENSMUSP00000045993N-myc proto-oncogene protein; Positively regulates the transcription of MYCNOS in neuroblastoma cells.
Ube3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000045998Ubiquitin-protein ligase E3C; E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquit [...]
Cdc14b protein networkhttps://string-db.org/network/10090.ENSMUSP00000046003Dual specificity protein phosphatase CDC14B; Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates [...]
Lyl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046010Protein lyl-1.
Apln protein networkhttps://string-db.org/network/10090.ENSMUSP00000046012Apelin-13; Endogenous ligand for the apelin receptor (APLNR). Drives internalization of APLNR (By similarity). Apelin-36 dissociates more hardly than (pyroglu)apelin-13 from APLNR (By similarity) [...]
Tmem108 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046021Transmembrane protein 108; Transmembrane protein required for proper cognitive functions. Involved in the development of dentate gyrus (DG) neuron circuitry, is necessary for AMPA receptors surfa [...]
Emx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046026Homeobox protein EMX1; Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations [...]
Itpk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046027Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1 [...]
Tmc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046028Transmembrane channel-like protein 3; Probable ion channel; Belongs to the TMC family.
Shisa4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046033Protein shisa-4.
Plekhh3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046044Pleckstrin homology domain-containing family H member 3.
Efl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046046Elongation factor-like GTPase 1; Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 [...]
Myh14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046059Myosin-14; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Belongs to the TRAFAC class myosin-kinesin ATPase super [...]
Fkbp14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046070Peptidyl-prolyl cis-trans isomerase FKBP14; PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4- hydroxylproline modifications, [...]
Bpifa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046080BPI fold-containing family A member 2; Has strong antibacterial activity against P. aeruginosa. Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
Rab26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046089Ras-related protein Rab-26; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle bet [...]
Adgrb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046097Adhesion G protein-coupled receptor B1; Phosphatidylserine receptor which enhances the engulfment of apoptotic cells. Also mediates the binding and engulfment of Gram-negative bacteria. Stimulate [...]
Eef2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046101Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
Kcnk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046103Potassium channel subfamily K member 1; Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but [...]
H2-Aa protein networkhttps://string-db.org/network/10090.ENSMUSP00000046105H-2 class II histocompatibility antigen, A-B alpha chain.
Minar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046111Major intrinsically disordered Notch2-binding receptor 1; Intrinsically disordered protein which may negatively regulate mTOR signaling pathway by stabilizing the mTOR complex component DEPTOR. N [...]
B3galt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046118Beta-1,3-galactosyltransferase 2; Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Can also [...]
Armc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046120Armadillo repeat-containing protein 7.
Asprv1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046121Retroviral-like aspartic protease 1.
Akap9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046129A-kinase anchor protein 9; Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Required to maintain the integrity of the Golgi appar [...]
Fgl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046131Fibroleukin; Converts prothrombin to thrombin.
Tcaf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046137TRPM8 channel-associated factor 1; Positively regulates the plasma membrane cation channel TRPM8 activity. Involved in the recruitment of TRPM8 to the cell surface. Promotes prostate cancer cell [...]
Bcl9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046152B-cell CLL/lymphoma 9 protein; Promotes beta-catenin's transcriptional activity. Involved in signal transduction through the Wnt pathway (By similarity).
Bphl protein networkhttps://string-db.org/network/10090.ENSMUSP00000046168Valacyclovir hydrolase; Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovi [...]
AA986860 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046172Specifically androgen-regulated gene protein; Putative androgen-specific receptor.
Abcb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046177ATP-binding cassette sub-family B member 5; Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of th [...]
Mbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000046185Myelin basic protein; The classic group of MBP isoforms (isoform 4-isoform 13) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its fo [...]
Rab24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046188Ras-related protein Rab-24; May be involved in autophagy-related processes; Belongs to the small GTPase superfamily. Rab family.
Elmod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046191ELMO domain-containing protein 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.
Srxn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046196Sulfiredoxin-1; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act o [...]
Ccdc68 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046197Coiled-coil domain-containing protein 68; Centriolar protein required for centriole subdistal appendage assembly and microtubule anchoring in interphase cells. Together with CCDC120, cooperate wi [...]
Stab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046199Stabilin-1; Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. [...]
Tex13b protein networkhttps://string-db.org/network/10090.ENSMUSP00000046203Testis expressed gene 13.
Hydin protein networkhttps://string-db.org/network/10090.ENSMUSP00000046204Hydrocephalus-inducing protein; Required for ciliary motility.
Spred3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046216Sprouty-related, EVH1 domain-containing protein 3; Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase.
Banf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046219Barrier-to-autointegration factor-like protein; May play a role in BANF1 regulation and influence tissue- specific roles of BANF1.
Btnl9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046229Butyrophilin-like protein 9; Belongs to the immunoglobulin superfamily. BTN/MOG family.
Npbwr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046233Neuropeptides B/W receptor type 1; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food inta [...]
Stx11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046243Syntaxin-11; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network.
Slc51a protein networkhttps://string-db.org/network/10090.ENSMUSP00000046286Organic solute transporter subunit alpha; Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export [...]
Fmnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046296Formin-like protein 1; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. May play a role in the con [...]
Cdnf protein networkhttps://string-db.org/network/10090.ENSMUSP00000046297Cerebral dopamine neurotrophic factor; Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-l [...]
Sdr16c5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046298Epidermal retinol dehydrogenase 2; Oxidoreductase with strong preference for NAD. Active in both the oxidative and reductive directions. Oxidizes all-trans-retinol in all-trans-retinaldehyde. No [...]
Bbox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046302Gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine; Belongs to the gamma-BBH/TMLD family.
Nenf protein networkhttps://string-db.org/network/10090.ENSMUSP00000046311Neudesin; Acts as a neurotrophic factor in postnatal mature neurons, enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the [...]
Ss18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046320Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, [...]
Lce3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000046325Late cornified envelope 3B.
Myo3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000046329Myosin-IIIa; Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing (By similarity). Required for normal cochlear hair bundle development and heari [...]
Grn protein networkhttps://string-db.org/network/10090.ENSMUSP00000046340Paragranulin; Secreted protein that acts as a key regulator of lysosomal function and as a growth factor involved in inflammation, wound healing and cell proliferation. Regulates protein traffick [...]
Dagla protein networkhttps://string-db.org/network/10090.ENSMUSP00000046358Sn1-specific diacylglycerol lipase alpha; Catalyzes the hydrolysis of diacylglycerol (DAG) to 2- arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal gr [...]
Tmtc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046368Protein O-mannosyl-transferase TMTC4; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl- transferases dedicated pr [...]
Kremen2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046369Kremen protein 2; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. Plays a role in limb de [...]
Gde1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046371Glycerophosphodiester phosphodiesterase 1; Has glycerophosphoinositol phosphodiesterase activity. Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding [...]
Ly6g6f protein networkhttps://string-db.org/network/10090.ENSMUSP00000046380Lymphocyte antigen 6 complex, locus G6F.
Ncoa5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046388Nuclear receptor coactivator 5; Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently [...]
Atg2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000046412Autophagy-related protein 2 homolog A; Involved in autophagosome assembly, regulating the size of nascent autophagosomes. Also regulates lipid droplets morphology and distribution within the cell [...]
Zer1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046441Protein zer-1 homolog; Serves as substrate adapter subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC. Acts redudantly with ZYG11B to target substrates bearing N-terminal glycine d [...]
Atp8b4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046444Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
Cc2d1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000046449Coiled-coil and C2 domain-containing protein 1A; Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The com [...]
Cars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046453Probable cysteine--tRNA ligase, mitochondrial.
Leng8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046465Leukocyte receptor cluster member 8 homolog.
Rnf139 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046467E3 ubiquitin-protein ligase RNF139; E3-ubiquitin ligase; acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I u [...]
Asb13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046476Ankyrin repeat and SOCS box protein 13; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquit [...]
Ostc protein networkhttps://string-db.org/network/10090.ENSMUSP00000046480Oligosaccharyltransferase complex subunit OSTC; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryote [...]
Arhgef3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046486Rho guanine nucleotide exchange factor 3; Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
Acad12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046497Acyl-Coenzyme A dehydrogenase family, member 12.
Nlrp4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000046503NACHT, LRR and PYD domains-containing protein 4C; May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound rec [...]
Rpl37 protein networkhttps://string-db.org/network/10090.ENSMUSP0000004650660S ribosomal protein L37; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.
Nrtn protein networkhttps://string-db.org/network/10090.ENSMUSP00000046512Neurturin; Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopo [...]
Zfp300 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046514Zinc finger protein 300.
Elf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046515ETS-related transcription factor Elf-1; Transcription factor that activates the LYN and BLK promoters; Belongs to the ETS family.
Cdo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046517Cysteine dioxygenase type 1; Belongs to the cysteine dioxygenase family.
Prl3a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046522Prolactin family 3, subfamily a, member 1.
Rftn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046524Raftlin; Involved in protein trafficking via association with clathrin and AP2 complex (By similarity). Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosome [...]
Scara3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046525Scavenger receptor class A member 3; Seems to protect cells by scavenging oxidative molecules or harmful products of oxidation.
Rsph6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000046526Radial spoke head protein 6 homolog A.
Slc35f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046528Solute carrier family 35 member F2; Putative solute transporter; Belongs to the SLC35F solute transporter family.
Itih2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046530Inter-alpha-trypsin inhibitor heavy chain H2; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in [...]
Grap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046532GRB2-related adaptor protein 2; Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc; Belongs to the GRB2/sem-5/DRK family.
Ap5m1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046536AP-5 complex subunit mu-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport.
Osbpl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046538Oxysterol-binding protein-related protein 2; Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma [...]
Camk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046539Calcium/calmodulin-dependent protein kinase type IV; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phos [...]
Nup54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046540Nuclear pore complex protein Nup54; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.
Sgsm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046544Small G protein signaling modulator 1; Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and R [...]
Clec18a protein networkhttps://string-db.org/network/10090.ENSMUSP00000046546C-type lectin domain family 18 member A.
Gng12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046557Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling s [...]
Igsf21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046558Immunoglobulin superfamily member 21; Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2.
Dipk2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000046567Divergent protein kinase domain 2B.
Plcl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046584Inactive phospholipase C-like protein 2; May play an role in the regulation of Ins(1,4,5)P3 around the endoplasmic reticulum.
Acsl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046585Long-chain-fatty-acid--CoA ligase 5; Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (B [...]
Eef2k protein networkhttps://string-db.org/network/10090.ENSMUSP00000046595Eukaryotic elongation factor 2 kinase; Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases incl [...]
Senp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046598Sentrin-specific protease 1; Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ub [...]
Pde1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000046601Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual-specificity for cAMP and cGMP, which are key regula [...]
Dpp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046604Dipeptidyl peptidase 9; Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. Belongs to the peptidase S9B family. DPPIV subfamily.
Igfbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046610Insulin-like growth factor-binding protein 2; Inhibits IGF-mediated growth and developmental rates (By similarity). IGF-binding proteins prolong the half-life of the IGFs and have been shown to e [...]
Cchcr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046612Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation.
Inpp5j protein networkhttps://string-db.org/network/10090.ENSMUSP00000046625Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; Inositol 5-phosphatase, which converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bi [...]
Gc protein networkhttps://string-db.org/network/10090.ENSMUSP00000046636Vitamin D-binding protein; Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation an [...]
Pdpr protein networkhttps://string-db.org/network/10090.ENSMUSP00000046639Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial; Decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine.
Zfp503 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046641Zinc finger protein 503; May function as a transcriptional repressor.
Utp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046643U3 small nucleolar RNA-associated protein 6 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the UTP6 family.
Ift57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046645Intraflagellar transport protein 57 homolog; Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway [...]
Snrnp25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046654U11/U12 small nuclear ribonucleoprotein 25 kDa protein.
Actr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046658Actin-related protein 5; Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Involved in DN [...]
Hjv protein networkhttps://string-db.org/network/10090.ENSMUSP00000046659Hemojuvelin; Acts as a bone morphogenetic protein (BMP) coreceptor. Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis.
Bpifb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046683BPI fold-containing family B, member 5.
Hhat protein networkhttps://string-db.org/network/10090.ENSMUSP00000046686Protein-cysteine N-palmitoyltransferase HHAT; Catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling during limb development. May bind GTP.
Ndp protein networkhttps://string-db.org/network/10090.ENSMUSP00000046692Norrin; Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing [...]
Lgi3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046705Leucine-rich repeat LGI family member 3; May participate in the regulation of neuronal exocytosis.
Slc7a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046714High affinity cationic amino acid transporter 1; High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues [...]
Magea4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046715Melanoma antigen, family A, 4.
Nup43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046732Nucleoporin Nup43; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex [...]
Cplx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046748Complexin-3; Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion. Required for the maintenance of synaptic ultrastructure in the adult retina. Positively regulates syn [...]
Gjb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046755Gap junction beta-3 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a [...]
Ipo8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046759Importin-8; Seems to function in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB [...]
Hectd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046766E3 ubiquitin-protein ligase HECTD1; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquiti [...]
Hsd17b13 protein networkhttps://string-db.org/network/10090.ENSMUSP0000004677217-beta-hydroxysteroid dehydrogenase 13.
Dennd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046774DENN domain-containing protein 3; Guanine nucleotide exchange factor (GEF) activating Rab12. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab12 into its active GTP-bound for [...]
Prr7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046776Proline-rich protein 7; Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-media [...]
Tspyl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046782Testis-specific Y-encoded-like protein 2; Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating [...]
Tmem183a protein networkhttps://string-db.org/network/10090.ENSMUSP00000046786Transmembrane protein 183.
Tbr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046787T-box brain protein 1; Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection. As transcri [...]
Hook3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046788Protein Hook homolog 3; Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting [...]
Foxf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046789Forkhead box protein F2; Probable transcription activator for a number of lung- specific genes. Mediates up-regulation of the E3 ligase IRF2BPL and drives ubiquitination and degradation of CTNNB1 [...]
Dusp26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046794Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity.
Dmrt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046812Doublesex- and mab-3-related transcription factor 3; Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates. Involved in neuronal spe [...]
Tekt5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046824Tektin-5; May be a structural component of the sperm flagellum.
Ptpa protein networkhttps://string-db.org/network/10090.ENSMUSP00000046837Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a [...]
Topors protein networkhttps://string-db.org/network/10090.ENSMUSP00000046843E3 ubiquitin-protein ligase Topors; Functions as an E3 ubiquitin-protein ligase and as a E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptos [...]
Lss protein networkhttps://string-db.org/network/10090.ENSMUSP00000046856Lanosterol synthase; Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein agg [...]
Kcnh5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046864Potassium voltage-gated channel subfamily H member 5; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a non-inactivating outward rectifying current (By similarity). Chann [...]
Tbc1d22b protein networkhttps://string-db.org/network/10090.ENSMUSP00000046877TBC1 domain family, member 22B.
Ttl protein networkhttps://string-db.org/network/10090.ENSMUSP00000046883Tubulin--tyrosine ligase; Catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin.
Ano5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046884Anoctamin-5; Does not exhibit calcium-activated chloride channel (CaCC) activity.
1110032A03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000046890UPF0686 protein C11orf1 homolog; Belongs to the UPF0686 family.
Myrip protein networkhttps://string-db.org/network/10090.ENSMUSP00000046891Rab effector MyRIP; Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicl [...]
Map11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046898Microtubule-associated protein 11; Microtubule associated protein wich seems to play a role in spindle dynamics and cell division.
Lat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046900Linker for activation of T-cells family member 2; Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen r [...]
Leo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046905RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development [...]
Ppp1r9a protein networkhttps://string-db.org/network/10090.ENSMUSP00000046906Neural tissue-specific F-actin binding protein.
Ms4a4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000046909Membrane-spanning 4-domains, subfamily A, member 4B.
Selenof protein networkhttps://string-db.org/network/10090.ENSMUSP00000046910Selenoprotein F; May be involved in redox reactions associated with the formation of disulfide bonds (By similarity). May contribute to the quality control of protein folding in the endoplasmic r [...]
Uts2r protein networkhttps://string-db.org/network/10090.ENSMUSP00000046920Urotensin-2 receptor; High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messeng [...]
Slc18a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046924Chromaffin granule amine transporter; Involved in the transport of biogenic monoamines, such as serotonin, from the cytoplasm into the secretory vesicles of neuroendocrine and endocrine cells.
Tmc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046927Transmembrane channel-like protein 7; Probable ion channel; Belongs to the TMC family.
Hoxa9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046939Homeobox protein Hox-A9; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Serpini2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046943Serpin I2; Belongs to the serpin family.
Il17f protein networkhttps://string-db.org/network/10090.ENSMUSP00000046960Interleukin-17F; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (By similarity). Involved in stimula [...]
Midn protein networkhttps://string-db.org/network/10090.ENSMUSP00000046967Midnolin; Facilitates ubiquitin-independent proteasomal degradation of polycomb protein CBX4. Plays a role in inhibiting the activity of glucokinase GCK and both glucose-induced and basal insulin [...]
Ric8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000046981Synembryn-B; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP (By similarity). Able to potentiate G(olf)-alpha [...]
Epgn protein networkhttps://string-db.org/network/10090.ENSMUSP00000046987Epigen; Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
Wipf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046991WAS/WASL-interacting protein family member 2; Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspik [...]
4930402H24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000046992Uncharacterized protein C20orf194 homolog; May act as an effector for ARL3.
Hand1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000046999Heart- and neural crest derivatives-expressed protein 1; Transcription factor that plays an essential role in both trophoblast giant cell differentiation and in cardiac morphogenesis. Binds the D [...]
Eif5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000047008Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of deca [...]
Fbxw8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047012F-box/WD repeat-containing protein 8; Substrate-recognition component of a Cul7-RING ubiquitin- protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of [...]
Churc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047015Protein Churchill; Transcriptional activator that mediates FGF signaling during neural development. Plays a role in the regulation of cell movement. Does not bind DNA by itself (By similarity); B [...]
Neurod6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047016Neurogenic differentiation factor 6; Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor involved in the development and maintenance of the mammal [...]
Dxo protein networkhttps://string-db.org/network/10090.ENSMUSP00000047018Decapping and exoribonuclease protein; Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphoh [...]
Cd300ld protein networkhttps://string-db.org/network/10090.ENSMUSP00000047022CMRF35-like molecule 5; Acts as an activating receptor in myeloid cells and mast cells; Belongs to the CD300 family.
Tspan15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047029Tetraspanin-15; Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10. Promotes ADAM10-mediated cleavage of (CDH2). Negatively regulates ligand-induced Notch activity p [...]
Erv3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047030Endogenous retroviral sequence 3.
Aadacl2fm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047032AADACL2 family member 1.
Syngr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047035Synaptogyrin-4.
Ankrd54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047042Ankyrin repeat domain-containing protein 54; Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation.
Dym protein networkhttps://string-db.org/network/10090.ENSMUSP00000047054Dymeclin; Necessary for correct organization of Golgi apparatus. Involved in bone development.
Clec1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000047065C-type lectin domain family 1 member A.
Eepd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047083Endonuclease/exonuclease/phosphatase family domain-containing protein 1.
6430571L13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000047093Uncharacterized protein C3orf18 homolog.
Tapbpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000047105Tapasin-related protein; Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I [...]
Zfp938 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047110Zinc finger protein 938.
Gnl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047119Guanine nucleotide-binding protein-like 3; May be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence protea [...]
Nop2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047123Probable 28S rRNA (cytosine-C(5))-methyltransferase; Involved in ribosomal large subunit assembly. S-adenosyl-L- methionine-dependent methyltransferase that specifically methylates the C(5) posit [...]
Nt5dc1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000471265'-nucleotidase domain-containing protein 1.
Glb1l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047128Beta-galactosidase-1-like protein 2; Belongs to the glycosyl hydrolase 35 family.
Lbx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047134Transcription factor LBX2; Putative transcription factor.
Cyp2g1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047150Cytochrome P450, family 2, subfamily g, polypeptide 1; Belongs to the cytochrome P450 family.
Aqr protein networkhttps://string-db.org/network/10090.ENSMUSP00000047157RNA helicase aquarius; Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre- mRNA splicing and snoRNP (small nucleolar ribonucle [...]
Capn8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047164Calpain-8; Calcium-regulated non-lysosomal thiol-protease (By similarity). Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking [...]
Pdlim7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047173PDZ and LIM domain protein 7; May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding pro [...]
Dap protein networkhttps://string-db.org/network/10090.ENSMUSP00000047186Death-associated protein 1; Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death (By similarity).
Gpc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047199Secreted glypican-1; Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By simila [...]
Ppp1r11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047202E3 ubiquitin-protein ligase PPP1R11; Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammato [...]
Dcun1d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047208DCN1-like protein 2; Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an [...]
Lrrc52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047213Leucine-rich repeat-containing protein 52; Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marke [...]
Grhpr protein networkhttps://string-db.org/network/10090.ENSMUSP00000047218Glyoxylate reductase/hydroxypyruvate reductase; Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glyce [...]
Zfp458 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047222Zinc finger protein 728.
Hpf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047235Histone PARylation factor 1; Acts as a cofactor for serine ADP-ribosylation by conferring serine specificity on PARP1 and PARP2: interacts with PARP1 and PARP2 and is able to change amino acid sp [...]
Rbbp8nl protein networkhttps://string-db.org/network/10090.ENSMUSP00000047237RBBP8 N-terminal-like.
Ankrd35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047244Ankyrin repeat domain 35.
Xylb protein networkhttps://string-db.org/network/10090.ENSMUSP00000047254Xylulose kinase; Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.
Fmnl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047260Formin-like protein 2; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics (By similarity); Belongs to the formin hom [...]
Mmp1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000047261Interstitial collagenase B; Belongs to the peptidase M10A family.
Chrnb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047270Acetylcholine receptor subunit beta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting chan [...]
Abitram protein networkhttps://string-db.org/network/10090.ENSMUSP00000047275Protein Abitram; Actin-binding protein that regulates actin polymerization, filopodia dynamics and increases the branching of proximal dendrites of developing neurons; Belongs to the ABITRAM fami [...]
Calhm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047278Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. Belongs to the CALHM family.
Tespa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047284Protein TESPA1; May play a role in the regulation of inositol 1,4,5- trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic ret [...]
Pak7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047285Serine/threonine-protein kinase PAK 5; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferat [...]
Olfml2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000047291Olfactomedin-like protein 2B.
Phf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047308Lysine-specific demethylase PHF2; Lysine demethylase that demethylates both histones and non- histone proteins. Enzymatically inactive by itself, and becomes active following phosphorylation by P [...]
Trmt13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047320tRNA:m(4)X modification enzyme TRM13 homolog; tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His). Belongs to the methyltransferase TRM [...]
Lgr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047325Leucine-rich repeat-containing G-protein coupled receptor 4; Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon [...]
Actr1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000047326Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (By similarity); Belongs to the actin family. ARP1 subfa [...]
Plekhm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047327Pleckstrin homology domain-containing family M member 1; Proposed to act as a multivalent adapter protein that regulates Rab7-dependent and HOPS complex-dependent fusion events in the endolysosom [...]
Zbtb7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000047333Zinc finger and BTB domain-containing protein 7A; Transcription factor that represses the transcription of a wide range of genes involved in cell proliferation and differentiation. Directly and s [...]
Wdr60 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047334WD repeat-containing protein 60; May play a role in ciliogenesis.
Spag1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047335Sperm-associated antigen 1; May play a role in the cytoplasmic assembly of the ciliary dynein arms (By similarity). May play a role in fertilization. Binds GTP and has GTPase activity (By similar [...]
Slc5a12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047340Sodium-coupled monocarboxylate transporter 2; Acts as an electroneutral and low-affinity sodium (Na(+))- dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma mem [...]
Prpmp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047347Proline-rich protein MP5.
Atp1b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047353Sodium/potassium-transporting ATPase subunit beta-2; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) io [...]
Igtp protein networkhttps://string-db.org/network/10090.ENSMUSP00000047356Interferon gamma-induced GTPase.
Mc3r protein networkhttps://string-db.org/network/10090.ENSMUSP00000047358Melanocortin receptor 3; Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patte [...]
Pitx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047359Pituitary homeobox 2; Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. [...]
Lonrf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047372LON peptidase N-terminal domain and ring finger 2.
Ptpdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047374Protein tyrosine phosphatase domain-containing protein 1; May play roles in cilia formation and/or maintenance.
Gls2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047376Glutaminase liver isoform, mitochondrial; Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing [...]
Piwil2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047385Piwi-like protein 2; Endoribonuclease that plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline i [...]
Dock4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047387Dedicator of cytokinesis protein 4; Involved in regulation of adherens junction between cells. Plays a role in cell migration. Functions as a guanine nucleotide exchange factor (GEF), which activ [...]
Bpgm protein networkhttps://string-db.org/network/10090.ENSMUSP00000047393Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits muta [...]
Sart1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047397U4/U6.U5 tri-snRNP-associated protein 1; Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA. Appears to pl [...]
Setd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047398Histone-lysine N-methyltransferase SETD5; Displays histone methyltransferase activity and monomethylates 'Lys-9' of histone H3 in vitro. The physiological significance of this activity is unclear [...]
Apobec2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047402C->U-editing enzyme APOBEC-2; Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase [...]
Mylip protein networkhttps://string-db.org/network/10090.ENSMUSP00000047403E3 ubiquitin-protein ligase MYLIP; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. A [...]
Tax1bp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047410Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling path [...]
Nthl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047413Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary [...]
Ly6d protein networkhttps://string-db.org/network/10090.ENSMUSP00000047419Lymphocyte antigen 6D; May act as a specification marker at earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification.
Tagap protein networkhttps://string-db.org/network/10090.ENSMUSP00000047431T-cell activation Rho GTPase-activating protein; May function as a GTPase-activating protein. May play a role in transmission ratio distortion (TRD) in mouse, in which heterozygous males for t-lo [...]
Atad2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000047445ATPase family, AAA domain-containing 2B.
Sapcd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047448Suppressor APC domain-containing protein 1.
Tlx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047457T-cell leukemia homeobox protein 3.
Usp28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047467Ubiquitin carboxyl-terminal hydrolase 28; Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability. Involved in DNA damage induced apoptosis by specifically deub [...]
Osgin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047473Oxidative stress-induced growth inhibitor family member 2.
Tceal9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047474Transcription elongation factor A protein-like 9; May be involved in transcriptional regulation; Belongs to the TFS-II family. TFA subfamily.
Trafd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047475TRAF-type zinc finger domain-containing protein 1; Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like heli [...]
Kcnab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047480Voltage-gated potassium channel subunit beta-1; Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Modulates action potentials via its [...]
Chsy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047487Chondroitin sulfate synthase 1; Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosam [...]
Klk1b26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047488Kallikrein 1-related peptidase b26; Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Timm8a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047497Putative mitochondrial import inner membrane translocase subunit Tim8 A-B; Putative mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmem [...]
Smyd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047505SET and MYND domain-containing protein 4.
Pcsk7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047508Proprotein convertase subtilisin/kexin type 7; Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely fu [...]
Ramp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047518Receptor activity-modifying protein 3; Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-relat [...]
Myf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047529Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.
Fbxo38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047541F-box only protein 38; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradat [...]
Ctdspl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047543CTD small phosphatase-like protein 2; Probable phosphatase; Belongs to the CTDSPL2 family.
Serinc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047547Serine incorporator 5; Restriction factor required to restrict infectivity of gammaretroviruses: acts by inhibiting early step of viral infection and impairing the ability of the viral particle t [...]
Ephx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047551Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Ma [...]
Trappc11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047562Trafficking protein particle complex subunit 11; Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage; Belongs to the TRAPPC11 family.
Pygm protein networkhttps://string-db.org/network/10090.ENSMUSP00000047564Glycogen phosphorylase, muscle form; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their [...]
Sox5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047567Transcription factor SOX-5; Binds specifically to the DNA sequence 5'-AACAAT-3'. Activates transcription of COL2A1 and AGC1 in vitro.
Card19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047569Caspase recruitment domain-containing protein 19; Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B.
Jmjd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047570Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Dioxygenase that can both act as a arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5- hydro [...]
Hnrnpu protein networkhttps://string-db.org/network/10090.ENSMUSP00000047571Heterogeneous nuclear ribonucleoprotein U; DNA- and RNA-binding protein involved in several cellular processes such as nuclear chromatin organization, telomere-length regulation, transcription, m [...]
Lrfn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047573Leucine-rich repeat and fibronectin type-III domain-containing protein 2; Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 [...]
Gngt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047586Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling s [...]
Coil protein networkhttps://string-db.org/network/10090.ENSMUSP00000047588Coilin; Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs.
Smarcal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047589SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA [...]
Rorb protein networkhttps://string-db.org/network/10090.ENSMUSP00000047597Nuclear receptor ROR-beta; Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence [...]
Zdhhc15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047615Palmitoyltransferase ZDHHC15; Catalyzes palmitoylation of Cys residues on target proteins. Catalyzes palmitoylation of GAP43 and DLG4/PSD95.
Fermt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047616Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte prolifera [...]
Wtip protein networkhttps://string-db.org/network/10090.ENSMUSP00000047623Wilms tumor protein 1-interacting protein; Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell [...]
Trim69 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047627E3 ubiquitin-protein ligase TRIM69; May have E3 ubiquitin-protein ligase activity. May play a role in apoptosis; Belongs to the TRIM/RBCC family.
Gpr19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047630Probable G-protein coupled receptor 19; Orphan receptor.
Mical2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047639[F-actin]-monooxygenase MICAL2; Nuclear monooxygenase that promotes depolymerization of F- actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resu [...]
Ptchd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047640Patched domain-containing protein 4; Could act as a repressor of canonical hedgehog signaling by antagonizing the effects of SMO, as suggested by down-regulation of hedgehog target genes, includi [...]
Cxcl10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047646C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of c [...]
Dock3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047652Dedicator of cytokinesis protein 3; Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with preseni [...]
Pof1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000047655Protein POF1B; Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development (By similarity).
Cox6a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047661Cytochrome c oxidase subunit 6A1, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The r [...]
Adk protein networkhttps://string-db.org/network/10090.ENSMUSP00000047665Adenosine kinase; ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular [...]
Mlc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047667Membrane protein MLC1; Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx.
Setd1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000047672Histone-lysine N-methyltransferase SETD1A; Histone methyltransferase that specifically methylates 'Lys- 4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if [...]
Prl3b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047680Prolactin-3B1; Belongs to the somatotropin/prolactin family.
Fam124a protein networkhttps://string-db.org/network/10090.ENSMUSP00000047681Family with sequence similarity 124, member A.
Atp6v0b protein networkhttps://string-db.org/network/10090.ENSMUSP00000047682V-type proton ATPase 21 kDa proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of [...]
Kdm2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000047683Lysine-specific demethylase 2A; Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated [...]
Slc6a20a protein networkhttps://string-db.org/network/10090.ENSMUSP00000047690Sodium- and chloride-dependent transporter XTRP3A; Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids.
Syne2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047697Nesprin-2; Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. As a component of the LINC [...]
Chmp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047700Charged multivesicular body protein 7; ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase. Together with SPAST, the ESCRT-III complex pr [...]
1700123O20Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000047702Uncharacterized protein C14orf119 homolog.
Kcnh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047705Potassium voltage-gated channel subfamily H member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit ass [...]
Cbr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047712Carbonyl reductase [NADPH] 3; Has low NADPH-dependent oxidoreductase activity towards 4- benzoylpyridine and menadione (in vitro).
Ssh3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047718Protein phosphatase Slingshot homolog 3; Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing [...]
Mettl17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047720Methyltransferase-like protein 17, mitochondrial; May be a component of the mitochondrial small ribosomal subunit; Belongs to the methyltransferase superfamily. Rsm22 family.
Sbspon protein networkhttps://string-db.org/network/10090.ENSMUSP00000047730Somatomedin-B and thrombospondin type-1 domain-containing protein.
Rab42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047735Ras-related protein Rab-42.
S100a13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047737Protein S100-A13; Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding o [...]
Pabpc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047756Poly(A)-binding protein, cytoplasmic 5.
Glyctk protein networkhttps://string-db.org/network/10090.ENSMUSP00000047761Glycerate kinase; Belongs to the glycerate kinase type-2 family.
Neb protein networkhttps://string-db.org/network/10090.ENSMUSP00000047763Nebulin.
H2-M10.5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047766Histocompatibility 2, M region locus 10.5; Belongs to the MHC class I family.
Atf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047771Cyclic AMP-dependent transcription factor ATF-5; Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP resp [...]
Htr2a protein networkhttps://string-db.org/network/10090.ENSMUSP000000477745-hydroxytryptamine receptor 2A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, p [...]
Fsd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047775Fibronectin type III and SPRY domain-containing protein 2.
Plpp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047776Phospholipid phosphatase 6; Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunit [...]
Nudt19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047778Nucleoside diphosphate-linked moiety X motif 19; Acyl-CoA diphosphatase that mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty- acyl-CoA esters [...]
Slfn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047782Schlafen family member 1.
Dnali1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047783Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family.
Cpsf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047797Cleavage and polyadenylation specificity factor subunit 2; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recog [...]
Wrap53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047825Telomerase Cajal body protein 1; RNA chaperone that plays a key role in telomere maintenance and RNA localization to Cajal bodies. Specifically recognizes and binds the Cajal body box (CAB box) p [...]
Trmt12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047831tRNA wybutosine-synthesizing protein 2 homolog; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guano [...]
Tbc1d25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047838TBC1 domain family member 25; Acts as a GTPase-activating protein specific for RAB33B. Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endoso [...]
Ppp1r13l protein networkhttps://string-db.org/network/10090.ENSMUSP00000047839RelA-associated inhibitor; Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Inhibits p53/TP53 function, [...]
Chad protein networkhttps://string-db.org/network/10090.ENSMUSP00000047844Chondroadherin; Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play a [...]
Dctpp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047845dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and [...]
Mcee protein networkhttps://string-db.org/network/10090.ENSMUSP00000047855Methylmalonyl-CoA epimerase, mitochondrial; Belongs to the methylmalonyl-CoA epimerase family.
Fam151a protein networkhttps://string-db.org/network/10090.ENSMUSP00000047860Protein FAM151A.
Sun2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047864SUN domain-containing protein 2; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nu [...]
Dhx38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047865DEAH (Asp-Glu-Ala-His) box polypeptide 38.
Smc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047872Structural maintenance of chromosomes protein 4; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The [...]
Fchsd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047878F-BAR and double SH3 domains protein 1; Promotes actin polymerization mediated by SNX9 and WASL.
Tbce protein networkhttps://string-db.org/network/10090.ENSMUSP00000047880Tubulin-specific chaperone E; Tubulin-folding protein; involved in the second step of the tubulin folding pathway and in the regulation of tubulin heterodimer dissociation. Required for correct o [...]
Dock9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047881Dedicator of cytokinesis protein 9; Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation (By similarity).
Cacng5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047888Voltage-dependent calcium channel gamma-5 subunit; Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of [...]
Inhba protein networkhttps://string-db.org/network/10090.ENSMUSP00000047894Inhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diver [...]
Ddx19a protein networkhttps://string-db.org/network/10090.ENSMUSP00000047898ATP-dependent RNA helicase DDX19A; ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19 functions as a remodeler of ribonucleoprotein par [...]
Dusp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047900Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
Cmc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047904COX assembly mitochondrial protein homolog; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome [...]
Slc16a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047912Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. [...]
Igsf23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047914Immunoglobulin superfamily, member 23.
Vars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047917Valine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
Colgalt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047923Procollagen galactosyltransferase 1; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen. By acting on collagen glycosylation, facilitates the fo [...]
Srpx protein networkhttps://string-db.org/network/10090.ENSMUSP00000047926Sushi-repeat-containing protein SRPX.
Abca5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047927ATP-binding cassette sub-family A member 5; May play a role in the processing of autolysosomes.
C1galt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047931Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for m [...]
Hoxd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047949Homeobox protein Hox-D4; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Cdc16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047950Cell division cycle protein 16 homolog; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the [...]
Foxn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047951Forkhead box protein N4; Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing t [...]
Iqch protein networkhttps://string-db.org/network/10090.ENSMUSP00000047953IQ domain-containing protein H; May play a regulatory role in spermatogenesis.
Cyp24a1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000479541,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; A cytochrome P450 monooxygenase with a key role in vitamin D catabolism and calcium homeostasis. Via C24-oxidation pathway, catalyzes the [...]
Atp5l protein networkhttps://string-db.org/network/10090.ENSMUSP00000047960ATP synthase subunit g, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
Alx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047962Homeobox protein aristaless-like 4; Transcription factor involved in skull and limb development; Belongs to the paired homeobox family.
S100b protein networkhttps://string-db.org/network/10090.ENSMUSP00000047968Protein S100-B; Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium io [...]
Vps37b protein networkhttps://string-db.org/network/10090.ENSMUSP00000047980Vacuolar protein sorting-associated protein 37B; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into mu [...]
Tram2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000047992Translocating chain-associated membrane protein 2; Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This couplin [...]
Coq5 protein networkhttps://string-db.org/network/10090.ENSMUSP000000480012-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-meth [...]
Hoxb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048002Homeobox protein Hox-B4; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Tubg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048036Tubulin gamma-1 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentrio [...]
Lrrc20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048042Leucine-rich repeat-containing protein 20.
Rccd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048043RCC1 domain-containing protein 1; Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possi [...]
Tiparp protein networkhttps://string-db.org/network/10090.ENSMUSP00000048051Protein mono-ADP-ribosyltransferase TIPARP; ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate, aspartate and cysteine residues on target proteins (By similarity). Acts as a [...]
Wfs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048053Wolframin; Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store.
Oas1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000048054Inactive 2'-5'-oligoadenylate synthase 1D; Does not have 2'-5'-olygoadenylate synthetase activity, but can bind double-stranded RNA. May play a role in the control of female fertility, possibly b [...]
Inppl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048057Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIn [...]
Gpr33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048059Probable G-protein coupled receptor 33; Orphan receptor; could be a chemoattractant receptor.
Tspoap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048063Peripheral-type benzodiazepine receptor-associated protein 1; Belongs to the RIMBP family.
Mrpl47 protein networkhttps://string-db.org/network/10090.ENSMUSP0000004807839S ribosomal protein L47, mitochondrial; Belongs to the universal ribosomal protein uL29 family.
Gdf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048079Growth/differentiation factor 5; Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstl [...]
Nup133 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048084Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport. Involved in nephrogenesis.
C3ar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048092C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion p [...]
Prorsd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048099Prolyl-tRNA synthetase associated domain-containing protein 1.
Nup88 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048101Nuclear pore complex protein Nup88; Component of nuclear pore complex.
Spr protein networkhttps://string-db.org/network/10090.ENSMUSP00000048111Sepiapterin reductase; Catalyzes the final one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
Ceacam2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048118Carcinoembryonic antigen-related cell adhesion molecule 2; Controls energy balance and peripheral insulin action. Involved in the regulation of feeding behavior particularly in the ventromedial n [...]
Ptpn13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048119Tyrosine-protein phosphatase non-receptor type 13; Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. May regulate phosphoinositide 3 [...]
Tent2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048124Poly(A) RNA polymerase GLD2; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly [...]
Spag11b protein networkhttps://string-db.org/network/10090.ENSMUSP00000048125Sperm-associated antigen 11B.
Gramd1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000048126Protein Aster-B; Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). Contains unique domains for binding [...]
Ifi207 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048129Interferon-activated gene 207.
Stac3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048148SH3 and cysteine-rich domain-containing protein 3; Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. [...]
Rbmxl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048153RNA binding motif protein, X-linked-like-1; RNA-binding protein which may be involved in pre-mRNA splicing.
Pate12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048154Prostate and testis-expressed 12.
Ror1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048171Inactive tyrosine-protein kinase transmembrane receptor ROR1; Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (By similarity). Receptor for ligand W [...]
Acd protein networkhttps://string-db.org/network/10090.ENSMUSP00000048180Adrenocortical dysplasia protein; Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-st [...]
Capn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048183Calpain-5; Calcium-regulated non-lysosomal thiol-protease.
Tex16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048187Testis-expressed gene 16.
Metap1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000048190Methionine aminopeptidase 1D, mitochondrial; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is [...]
Zdhhc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048198Palmitoyltransferase ZDHHC5; Palmitoyl acyltransferase for the G-protein coupled receptor SSTR5 and for FLOT2.
Susd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048201Sushi domain-containing 1.
Utp15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048204U3 small nucleolar RNA-associated protein 15 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription b [...]
Cnst protein networkhttps://string-db.org/network/10090.ENSMUSP00000048205Consortin; Required for targeting of connexins to the plasma membrane.
Plekha6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048214Pleckstrin homology domain-containing family A member 6.
Acta2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048218Actin, aortic smooth muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Mat2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000048222Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Reg [...]
Setmar protein networkhttps://string-db.org/network/10090.ENSMUSP00000048225Histone-lysine N-methyltransferase SETMAR; Histone methyltransferase that methylates 'Lys-4' and 'Lys- 36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically m [...]
Lyplal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048229Lysophospholipase-like protein 1; Has depalmitoylating activity toward KCNMA1. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates du [...]
Rflna protein networkhttps://string-db.org/network/10090.ENSMUSP00000048230Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in the formation of cartilaginous skeletal elem [...]
Ick protein networkhttps://string-db.org/network/10090.ENSMUSP00000048234Serine/threonine-protein kinase ICK; Has an essential role in ciliogenesis, particularly in neuronal and retinal progenitor cells. Phosphorylates KIF3A. Involved in the control of ciliary length. [...]
Lmtk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048238Serine/threonine-protein kinase LMTK2; Phosphorylates PPP1C, phosphorylase b and CFTR. Belongs to the protein kinase superfamily. Tyr protein kinase family.
Gpbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048240Vasculin; Functions as a GC-rich promoter-specific transactivating transcription factor.
Tbc1d17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048260TBC1 domain family member 17; Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transf [...]
Mnd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048262Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates both DMC1- and RAD51 [...]
Nutm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048263NUT family member 1; Plays a role in the regulation of proliferation. Regulates TERT expression by modulating SP1 binding to TERT promoter binding sites; Belongs to the NUT family.
Rassf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048267Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.
Rnasek protein networkhttps://string-db.org/network/10090.ENSMUSP00000048271Ribonuclease kappa; Endoribonuclease which preferentially cleaves ApU and ApG phosphodiester bonds. Hydrolyzes UpU bonds at a lower rate (By similarity); Belongs to the RNase K family.
Cyp2c54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048284Cytochrome P450 2C54; Metabolizes arachidonic acid mainly to 12- hydroxyeicosatetraenoic acid (HETE); Belongs to the cytochrome P450 family.
Metap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048285Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence [...]
Fcmr protein networkhttps://string-db.org/network/10090.ENSMUSP00000048303Fas apoptotic inhibitory molecule 3; May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitor [...]
Stab2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048309Short form stabilin-2; Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, [...]
Sptlc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048313Serine palmitoyltransferase 3; Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) [...]
Orc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048319Origin recognition complex subunit 3; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define ori [...]
Cc2d2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000048320Coiled-coil and C2 domain-containing protein 2A; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusio [...]
Kcnk15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048326Potassium channel subfamily K member.
Fbln2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048334Fibulin-2; Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN; Belongs to the fibulin family.
Wdr43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048337WD repeat-containing protein 43; Ribosome biogenesis factor that coordinates hyperactive transcription and ribogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for opt [...]
Ythdc2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000483403'-5' RNA helicase YTHDC2; 3'-5' RNA helicase that plays a key role in the male and female germline by promoting transition from mitotic to meiotic divisions in stem cells. Specifically recognize [...]
Hectd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048345HECT domain E3 ubiquitin protein ligase 4.
Mrps35 protein networkhttps://string-db.org/network/10090.ENSMUSP0000004834828S ribosomal protein S35, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS35 family.
Vat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048350Synaptic vesicle membrane protein VAT-1 homolog; Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms. Has no effect on cell proliferation (By similarity). Pos [...]
Serpina10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048357Protein Z-dependent protease inhibitor; Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofa [...]
Ltb4r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048358Leukotriene B4 receptor 2; Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activ [...]
Actrt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048360Actin-related protein T3; Belongs to the actin family.
Malt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048376Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 ol [...]
Utp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048377U3 small nucleolar RNA-associated protein 4 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in small subunit (SSU) pre-rRNA processing at [...]
Kif4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048383Chromosome-associated kinesin KIF4; Required for mitotic chromosomal positioning and bipolar spindle stabilization.
1110059E24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000048395Uncharacterized protein C9orf85 homolog.
Josd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048415Josephin-2; Cleaves 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme (By similarity).
Cops4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048416COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an esse [...]
Pebp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048425Hippocampal cholinergic neurostimulating peptide; Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor w [...]
Tbc1d13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048426TBC1 domain family member 13; Acts as a GTPase-activating protein for RAB35. Together with RAB35 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to [...]
Mustn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048427Musculoskeletal embryonic nuclear protein 1; May be involved in the development and regeneration of the musculoskeletal system; Belongs to the MUSTANG family.
Krt25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048439Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). [...]
9530068E07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000048441Keratinocyte-associated transmembrane protein 2.
Ppp1r21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048443Protein phosphatase 1 regulatory subunit 21; utative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.
Rbm34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048450RNA-binding protein 34.
Rasl10a protein networkhttps://string-db.org/network/10090.ENSMUSP00000048453Ras-like protein family member 10A; Potent inhibitor of cellular proliferation.
Armh3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048454Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion; Belongs to the ARMH3 family.
Surf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048457Surfeit locus protein 6; Binds to both DNA and RNA in vitro, with a stronger binding capacity for RNA. May represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembl [...]
Fxyd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048460Phospholemman; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in [...]
Rpl10a protein networkhttps://string-db.org/network/10090.ENSMUSP0000004846960S ribosomal protein L10a; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL1 family.
Rbm25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048470RNA-binding protein 25; RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isofo [...]
Acmsd protein networkhttps://string-db.org/network/10090.ENSMUSP000000484822-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non [...]
Coro7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048489Coronin-7; F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interact [...]
Gbx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048508Homeobox protein GBX-2; May act as a transcription factor for cell pluripotency and differentiation in the embryo.
Tbc1d16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048516TBC1 domain family, member 16.
Degs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048519Sphingolipid delta(4)-desaturase DES1; Has sphingolipid-delta-4-desaturase activity. Converts D- erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine).
Sox15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048524Protein SOX-15; Transcription factor that binds to DNA at the 5'-AACAATG-3' consensus sequence. Acts as a transcriptional activator and repressor. Binds synergistically with POU5F1 (OCT3/4) to ge [...]
Btbd10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048530BTB/POZ domain-containing protein 10; Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in pre [...]
Smyd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048537SET and MYND domain-containing protein 5.
Scgb2b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048540Secretoglobin family 2B member 2; Belongs to the secretoglobin family.
Cpe protein networkhttps://string-db.org/network/10090.ENSMUSP00000048555Carboxypeptidase E; Sorting receptor that directs prohormones to the regulated secretory pathway. Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues f [...]
Lin37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048557Protein lin-37 homolog.
Cpa4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048558Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val; B [...]
Fbxl16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048562F-box/LRR-repeat protein 16; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Mgl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048568Macrophage galactose N-acetyl-galactosamine-specific lectin 2.
Agpat1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000485731-acyl-sn-glycerol-3-phosphate acyltransferase alpha; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by i [...]
Grin3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000048576Glutamate receptor ionotropic, NMDA 3B; NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivi [...]
Tex19.1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048592Testis-expressed protein 19.1; Required during spermatogenesis and placenta development, participating in the repression of retrotransposable elements and preventing their mobilization. With its [...]
Aagab protein networkhttps://string-db.org/network/10090.ENSMUSP00000048595Alpha- and gamma-adaptin-binding protein p34; May be involved in endocytic recycling of growth factor receptors such as EGFR.
Cdsn protein networkhttps://string-db.org/network/10090.ENSMUSP00000048596Corneodesmosin; Important for the epidermal barrier integrity.
Cog6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048603Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
Cer1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048607Cerberus; Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part, through a BMP- inhibitory mechanism. Can regulate Nodal signaling during ga [...]
Mettl18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048636Histidine protein methyltransferase 1 homolog; Probable histidine methyltransferase; Belongs to the methyltransferase superfamily. METTL18 family.
Glt6d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048642Glycosyltransferase 6 domain-containing protein 1; Belongs to the glycosyltransferase 6 family.
Tigar protein networkhttps://string-db.org/network/10090.ENSMUSP00000048643Fructose-2,6-bisphosphatase TIGAR; Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate (By similarity). Acts as a negative regulator of glycolysis b [...]
Hoxa7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048648Homeobox protein Hox-A7; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
1700028J19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000048665RIKEN cDNA 1700028J19 gene.
F13a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048667Coagulation factor XIII A chain; Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibr [...]
Pakap protein networkhttps://string-db.org/network/10090.ENSMUSP00000048678A-kinase anchor protein 2; Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream [...]
1700028P14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000048680Protein C9orf135 homolog.
Znrd1as protein networkhttps://string-db.org/network/10090.ENSMUSP00000048695Putative uncharacterized protein ZNRD1-AS1; May be involved in male sterility.
Tbcc protein networkhttps://string-db.org/network/10090.ENSMUSP00000048696Tubulin-specific chaperone C; Tubulin-folding protein; involved in the final step of the tubulin folding pathway.
Serpinf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048704Alpha-2-antiplasmin; Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase- 3/TMPRSS7 and chymotrypsin (By similarity).
Vmn2r107 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048706Vomeronasal 2, receptor 107.
Npat protein networkhttps://string-db.org/network/10090.ENSMUSP00000048709Protein NPAT; Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 gene [...]
Dnajc16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048714DnaJ homolog subfamily C member 16.
Rims2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048719Regulating synaptic membrane exocytosis protein 2; Rab effector involved in exocytosis. May act as scaffold protein. Plays a role in dendrite formation by melanocytes (By similarity).
Spaca5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048721Sperm acrosome-associated protein 5; Belongs to the glycosyl hydrolase 22 family.
Scgb1c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048722Secretoglobin family 1C member 1.
Zcwpw1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048730Zinc finger CW-type PWWP domain protein 1.
Ptger4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048736Prostaglandin E2 receptor EP4 subtype; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on [...]
Olfr6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048740Olfactory receptor 6; Odorant receptor.
Bsdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048742BSD domain-containing protein 1.
Alpk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048752Alpha-protein kinase 2; Protein kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation. Regulates cardiac development and cardiomyocyte [...]
Pih1h3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000048754PIH1 domain-containing 3B.
Naif1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048764Nuclear apoptosis-inducing factor 1; Induces apoptosis.
Kdf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048768Keratinocyte differentiation factor 1; Plays a role in the regulation of the epidermis formation during early development. Required both as an inhibitor of basal cell proliferation and a promoter [...]
Atp6v1g1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048770V-type proton ATPase subunit G 1; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in e [...]
Akap14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048773A kinase (PRKA) anchor protein 14.
Arel1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048780Apoptosis-resistant E3 ubiquitin protein ligase 1; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfe [...]
Ddx52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048802Probable ATP-dependent RNA helicase DDX52; Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
Prelp protein networkhttps://string-db.org/network/10090.ENSMUSP00000048803Prolargin; May anchor basement membranes to the underlying connective tissue.
Ttll5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048809Tubulin polyglutamylase TTLL5; Polyglutamylase which preferentially modifies alpha-tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongat [...]
Hspb11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048810Intraflagellar transport protein 25 homolog; Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH components: required for the export of SMO and [...]
Zmynd15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048816Zinc finger MYND domain-containing protein 15; Acts as a transcriptional repressor through interaction with histone deacetylases (HDACs). May regulate haploid genes important for spermiogenesis.
Hspa13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048817Heat shock 70 kDa protein 13; Has peptide-independent ATPase activity; Belongs to the heat shock protein 70 family.
Klf16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048825Krueppel-like factor 16; Transcription factor that binds GC and GT boxes in the D1A, D2 and D3 dopamine receptor promoters and displaces Sp1 and Sp3 from these sequences. It modulates dopaminergi [...]
Mmaa protein networkhttps://string-db.org/network/10090.ENSMUSP00000048826Methylmalonic aciduria type A homolog, mitochondrial; GTPase, binds and hydrolyzes GTP. Involved in intracellular vitamin B12 metabolism, mediates the transport of cobalamin (Cbl) into mitochondr [...]
Cdh26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048829Cadherin-like protein 26; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contr [...]
Akr1d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048830Aldo-keto reductase family 1 member D1; Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one s [...]
C1qa protein networkhttps://string-db.org/network/10090.ENSMUSP00000048836Complement C1q subcomponent subunit A; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact wi [...]
Rarg protein networkhttps://string-db.org/network/10090.ENSMUSP00000048838Retinoic acid receptor gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic [...]
Cdrt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048844CMT1A duplicated region transcript 4 protein homolog.
Kcne2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048849Potassium voltage-gated channel subfamily E member 2; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates t [...]
Calm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048857Calmodulin 2.
Tsga10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048859Testis-specific gene 10 protein; Plays a role in spermatogenesis. When overexpressed, prevents nuclear localization of HIF1A ; Belongs to the CEP135/TSGA10 family.
Srd5a2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000488623-oxo-5-alpha-steroid 4-dehydrogenase 2; Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It pl [...]
Parp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048877Poly [ADP-ribose] polymerase 2; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. Mainly mediates glutamate and aspartate ADP- ribos [...]
Igsf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048900Immunoglobulin superfamily member 3.
Mvb12b protein networkhttps://string-db.org/network/10090.ENSMUSP00000048901Multivesicular body subunit 12B; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bod [...]
Fam160b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048903Protein FAM160B1.
Hsf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048904Heat shock factor protein 4; DNA-binding protein that specifically binds heat shock promoter elements (HSE). The HSF4A isoform represses transcription while the HSF4B isoform activates transcript [...]
Garem1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048914GRB2-associated and regulator of MAPK protein; Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth fac [...]
Vwa8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048925Von Willebrand factor A domain-containing protein 8; Exhibits ATPase activity in vitro.
Aox4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048929Aldehyde oxidase 4; Aldehyde oxidase able to catalyze the oxidation of retinaldehyde into retinoate. Is responsible for the major all-trans- retinaldehyde-metabolizing activity in the Harderian g [...]
Spsb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048969SPRY domain-containing SOCS box protein 1; Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitina [...]
Sirt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048971NAD-dependent protein deacetylase sirtuin-6; NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chrom [...]
Ccdc88a protein networkhttps://string-db.org/network/10090.ENSMUSP00000048978Girdin; Bifunctional modulator of guanine nucleotide-binding proteins (G proteins) (By similarity). Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine [...]
Thap11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000048994THAP domain-containing protein 11; Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor th [...]
Ndufv3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049000NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involve [...]
Greb1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000049003GREB1-like protein; Plays a major role in early metanephros and genital development; Belongs to the GREB1 family.
Ctnna1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049007Catenin alpha-1; Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and w [...]
Mslnl protein networkhttps://string-db.org/network/10090.ENSMUSP00000049020Mesothelin-like protein; May play a role in cellular adhesion; Belongs to the mesothelin family.
Fnip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049026Folliculin-interacting protein 1; Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client pr [...]
Ep400 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049038E1A-binding protein p400; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone [...]
Arx protein networkhttps://string-db.org/network/10090.ENSMUSP00000049039Homeobox protein ARX; Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the [...]
Immp1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000049044Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into th [...]
Pif1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049046ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) [...]
Ppp1r3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000049054Protein phosphatase 1 regulatory subunit 3A; Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, m [...]
Nek9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049056Serine/threonine-protein kinase Nek9; Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, [...]
Trim37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049057E3 ubiquitin-protein ligase TRIM37; E3 ubiquitin-protein ligase required to prevent centriole reduplication (By similarity). Probably acts by ubiquitinating positive regulators of centriole redup [...]
Rhbdd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049060Rhomboid domain-containing protein 2.
Trpc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049063Short transient receptor potential channel 5; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger s [...]
Tulp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049070Tubby-related protein 1; Required for normal development of photoreceptor synapses. Required for normal photoreceptor function and for long-term survival of photoreceptor cells. Interacts with cy [...]
Ins1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049095Insulin-1 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate [...]
Slc2a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049103Solute carrier family 2, facilitated glucose transporter member 6; Probable sugar transporter that acts as a regulator of glycolysis in macrophages. Does not transport glucose (By similarity).
Gbp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049104Guanylate-binding protein 7.
Sltm protein networkhttps://string-db.org/network/10090.ENSMUSP00000049112SAFB-like transcription modulator; When overexpressed, acts as a general inhibitor of transcription that eventually leads to apoptosis.
Alkbh5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049116RNA demethylase ALKBH5; Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messeng [...]
Acbd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049124Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very wea [...]
Cul7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049128Cullin-7; Core component of the 3M and Cul7-RING(FBXW8) complexes, which mediates the ubiquitination of target proteins. Core component of the 3M complex, a complex required to regulate microtubu [...]
Edc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049146Enhancer of mRNA-decapping protein 3; Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping (By similarity); Belongs to the EDC3 [...]
Ska1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049156Spindle and kinetochore-associated protein 1; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Require [...]
Ctf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049161Cardiotrophin-1; Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
Fam117a protein networkhttps://string-db.org/network/10090.ENSMUSP00000049162Protein FAM117A.
Rwdd2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000049168RWD domain-containing protein 2B.
Gna15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049175Guanine nucleotide-binding protein subunit alpha-15; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Patj protein networkhttps://string-db.org/network/10090.ENSMUSP00000049176InaD-like protein; Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane (By similarity). May regulate protein targeting, cell polarity and integrity [...]
Gfer protein networkhttps://string-db.org/network/10090.ENSMUSP00000049186FAD-linked sulfhydryl oxidase ALR; FAD-dependent sulfhydryl oxidase that regenerates the redox- active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and prot [...]
Kcnh8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049206Potassium voltage-gated channel subfamily H member 8; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, outward rectifying current (By similarity). Cha [...]
Agr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049212Anterior gradient protein 3; Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calci [...]
Cftr protein networkhttps://string-db.org/network/10090.ENSMUSP00000049228Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates th [...]
Gipc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049236PDZ domain-containing protein GIPC3; Required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion.
Tulp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049248Tubby-related protein 4; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent [...]
Lpcat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049252Lysophosphatidylcholine acyltransferase 2; Possesses both acyltransferase and acetyltransferase activities. Activity is calcium- dependent. Involved in platelet-activating factor (PAF) biosynthes [...]
Ambra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049258Activating molecule in BECN1-regulated autophagy protein 1; Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal develo [...]
Ccdc174 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049280Coiled-coil domain-containing protein 174; Probably involved in neuronal development.
Ints14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049284Integrator complex subunit 14; Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent proce [...]
Colec11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049285Collectin-11; Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharide [...]
Pkd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049296Polycystin-1; Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Both [...]
Prph protein networkhttps://string-db.org/network/10090.ENSMUSP00000049303Peripherin; Class-III neuronal intermediate filament protein; Belongs to the intermediate filament family.
Ces2g protein networkhttps://string-db.org/network/10090.ENSMUSP00000049315Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
Nubp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049319Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP [...]
Rnf13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049331E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation. Involved in apoptosis regulation. Mediates ER stress-induced activation of J [...]
Ift172 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049335Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the [...]
Spire1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049336Protein spire homolog 1; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibe [...]
Nipsnap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049338Protein NipSnap homolog 1; Belongs to the NipSnap family.
Klk5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049339Kallikrein-related-peptidase 5; Belongs to the peptidase S1 family.
Upb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049342Beta-ureidopropionase; Catalyzes a late step in pyrimidine degradation. Converts N- carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N [...]
Xkr7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049346XK-related protein 7.
Gpi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049355Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeog [...]
Adgrf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049380Adhesion G-protein coupled receptor F1; Orphan receptor.
Bbs10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049387Bardet-Biedl syndrome 10 protein homolog; Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in cili [...]
Aox3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049391Aldehyde oxidase 3; Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and phthalazine, as well as aldehydes, such as benzaldehyde, retina [...]
Cbr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049394Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menad [...]
Znfx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049404NFX1-type zinc finger-containing protein 1.
Dusp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049414Dual specificity protein phosphatase 8; Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing [...]
Zmat4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049430Zinc finger matrin-type protein 4.
Arpin protein networkhttps://string-db.org/network/10090.ENSMUSP00000049440Arpin; Regulates actin polymerization by inhibiting the actin- nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors. Participates in an incoher [...]
Cacna2d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049457Voltage-dependent calcium channel subunit alpha-2/delta-1; The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics o [...]
Plekhh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049460Pleckstrin homology domain-containing family H member 1.
Slc22a20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049473Solute carrier family 22 member 20; Organic anion transporter that mediates the uptake of estrone sulfate. Inhibited by probenecid, propionate, 2-methylbutyrate, 3- methylbutyrate, benzoate, hept [...]
Zswim5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049474Zinc finger SWIM domain-containing protein 5.
Nacad protein networkhttps://string-db.org/network/10090.ENSMUSP00000049490NAC-alpha domain-containing protein 1; May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge f [...]
Cyp3a59 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049494Cytochrome P450, family 3, subfamily a, polypeptide 59.
Ccdc113 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049497Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation.
Taar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049527Trace amine-associated receptor 1; Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Un [...]
Rbbp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049528E3 ubiquitin-protein ligase RBBP6; E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome (By similarity). May play a role as a scaffold p [...]
Gja8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049532Gap junction alpha-8 protein; Structural component of eye lens gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking [...]
Spn protein networkhttps://string-db.org/network/10090.ENSMUSP00000049534CD43 cytoplasmic tail; Predominant cell surface sialoprotein of leukocytes which regulates multiple T-cell functions, including T-cell activation, proliferation, differentiation, trafficking and [...]
Ccdc74a protein networkhttps://string-db.org/network/10090.ENSMUSP00000049541Coiled-coil domain-containing 74A.
Mfap1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000049548Microfibrillar-associated protein 1A; Involved in pre-mRNA splicing as a component of the spliceosome.
Prr15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049549Proline-rich protein 15; May have a role in proliferation and/or differentiation.
Bsnd protein networkhttps://string-db.org/network/10090.ENSMUSP00000049563Barttin; Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stri [...]
Itpr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049584Inositol 1,4,5-trisphosphate receptor type 2; Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP b [...]
Gpr150 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049592Probable G-protein coupled receptor 150; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Pycrl protein networkhttps://string-db.org/network/10090.ENSMUSP00000049605Pyrroline-5-carboxylate reductase 3; Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carb [...]
4930451I11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000049614RIKEN cDNA 4930451I11 gene.
Gpat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049619Glycerol-3-phosphate acyltransferase 2, mitochondrial; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Required f [...]
Gtf2i protein networkhttps://string-db.org/network/10090.ENSMUSP00000049625General transcription factor II-I; Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal resp [...]
Grem2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049640Gremlin-2; Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morph [...]
Zfp759 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049650Regulator of sex-limitation candidate 8.
Cpne4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049663Copine-4; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes. Belongs to the copine family.
Slc22a17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049676Solute carrier family 22 member 17; Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo- 24p3), followed by internali [...]
Ucn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049678Urocortin-3; Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress (By similarity); Belon [...]
Ch25h protein networkhttps://string-db.org/network/10090.ENSMUSP00000049683Cholesterol 25-hydroxylase; Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. Plays a key role in cell positioning and moveme [...]
Lrrc25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049686Leucine-rich repeat-containing protein 25; Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting DDX58/RIG-I for autophagic degradation. Interacts specif [...]
Fam243 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049694Protein FAM243A; Belongs to the FAM243 family.
Rexo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049705RNA exonuclease 1 homolog; Seems to have no detectable effect on transcription elongation in vitro.
Gpr158 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049708Probable G-protein coupled receptor 158; Orphan receptor; Belongs to the G-protein coupled receptor 3 family.
Hsfy2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049715Heat shock transcription factor, Y-linked 2.
Nek6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049723Serine/threonine-protein kinase Nek6; Protein kinase which plays an important role in mitotic cell cycle progression. Required for chromosome segregation at metaphase- anaphase transition, robust [...]
Cldn23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049725Claudin-23; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
Masp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049729Mannan-binding lectin serine protease 2 A chain; Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-cataly [...]
Gltpd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049732Glycolipid transfer protein domain-containing protein 2; Belongs to the GLTP family.
Rab9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000049739Ras-related protein Rab-9B; Involved in the transport of proteins between the endosomes and the trans Golgi network; Belongs to the small GTPase superfamily. Rab family.
Tcaim protein networkhttps://string-db.org/network/10090.ENSMUSP00000049759T-cell activation inhibitor, mitochondrial; May regulate T-cell apoptosis.
Mars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049770Methionine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
Ankfn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049776Ankyrin-repeat and fibronectin type III domain-containing 1.
Serpinb9h protein networkhttps://string-db.org/network/10090.ENSMUSP00000049819Serine (or cysteine) peptidase inhibitor, clade B, member 9h; Belongs to the serpin family.
Iba57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049823Putative transferase CAF17 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Belongs to the GcvT fa [...]
1700012B09Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000049826Uncharacterized protein C11orf97 homolog.
Tmem212 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049832Transmembrane protein 212.
Cir1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049834Corepressor interacting with RBPJ 1; Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression [...]
Gm6583 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049839Predicted gene 6583.
Ino80e protein networkhttps://string-db.org/network/10090.ENSMUSP00000049851INO80 complex subunit E.
Fzd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049852Frizzled-4; Receptor for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin (CTNNB1) canonical signaling pathway, which leads to the activation of disheveled proteins, inhibiti [...]
AY074887 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049861Cleft palate-related protein 1.
Ccdc54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049864Coiled-coil domain-containing protein 54.
Nkx2-6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049898Homeobox protein Nkx-2.6; Acts as a transcriptional activator (By similarity). In conjunction with NKX2-5, may play a role in both pharyngeal and cardiac embryonic development.
Trim2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049902Tripartite motif-containing protein 2; UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May p [...]
Ccdc60 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049912Coiled-coil domain-containing protein 60.
Gm6377 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049931Predicted gene, EG622976.
Olfr624 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049938Olfactory receptor.
Hrh3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049963Histamine H3 receptor; The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and dis [...]
Tbc1d8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049967TBC1 domain family member 8; May act as a GTPase-activating protein for Rab family protein(s).
Haus3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049973HAUS augmin-like complex subunit 3; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex; Belongs to [...]
Chst9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049975Carbohydrate sulfotransferase 9; Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Participates in biosynth [...]
Slk protein networkhttps://string-db.org/network/10090.ENSMUSP00000049977STE20-like serine/threonine-protein kinase; Mediates apoptosis and actin stress fiber dissolution.
Zbtb33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049983Transcriptional regulator Kaiso; Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the n [...]
Mettl24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000049997Methyltransferase-like protein 24.
Ccny protein networkhttps://string-db.org/network/10090.ENSMUSP00000050001Cyclin-Y; Positive regulatory subunit of the cyclin-dependent kinase CDK14/PFTK1. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma [...]
Rilpl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050014RILP-like protein 1; Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus (By similarity). Competes with SIAH1 for bi [...]
Teddm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050017Transmembrane epididymal family member 2.
Dclk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050034Serine/threonine-protein kinase DCLK1; Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in function [...]
Cnrip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050036CB1 cannabinoid receptor-interacting protein 1; Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.
Lrfn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050039Leucine-rich repeat and fibronectin type-III domain-containing protein 4; Promotes neurite outgrowth in hippocampal neurons. May play a role in redistributing DLG4 to the cell periphery.
E2f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050047Transcription factor E2F2; Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of gen [...]
Fhl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050054Four and a half LIM domains 4.
Acy3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050056N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acid [...]
Cyb5r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050061NADH-cytochrome b5 reductase 2; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemogl [...]
Adrm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050076Proteasomal ubiquitin receptor ADRM1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in [...]
Oprd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050077Delta-type opioid receptor; G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that tr [...]
Tesk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050087Dual specificity testis-specific protein kinase 1; Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and [...]
Rnf152 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050103E3 ubiquitin-protein ligase RNF152; E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and [...]
Pnpla1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050123Patatin-like phospholipase domain-containing protein 1; Lipid hydrolase.
Aqp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050127Aquaporin-9; Forms a water channel with a broad specificity. Also permeable glycerol and urea. Mediates passage of a wide variety of small, non-charged solutes including carbamides, polyols, puri [...]
2310057M21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000050128ATPase PAAT; ATPase that regulates mitochondrial ABC transporters ABCB7, ABCB8/MITOSUR and ABCB10. Regulates mitochondrial ferric concentration and heme biosynthesis and plays a role in the maint [...]
Tnfsf15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050144Tumor necrosis factor ligand superfamily member 15; Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promot [...]
Timm8a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050156Mitochondrial import inner membrane translocase subunit Tim8 A; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into [...]
Prmt9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050181Protein arginine N-methyltransferase 9; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically m [...]
Olfr745 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050184Olfactory receptor.
Ccni protein networkhttps://string-db.org/network/10090.ENSMUSP00000050189Cyclin-I; Belongs to the cyclin family.
Ubqln1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050191Ubiquilin-1; Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin- proteasome system (UPS), autophagy and endoplasmic reticulum-a [...]
Tafa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050199Chemokine-like protein TAFA-2; Has a role as neurotrophic factor involved in neuronal survival and neurobiological functions.
Mtss2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050211Protein MTSS 2; Involved in plasma membrane dynamics. Potentiated PDGF- mediated formation of membrane ruffles and lamellipodia in fibroblasts, acting via RAC1 activation. May function in actin b [...]
Klhl23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050219Kelch-like protein 23.
Fam221a protein networkhttps://string-db.org/network/10090.ENSMUSP00000050237Protein FAM221A.
Xxylt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050246Xyloside xylosyltransferase 1; Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins b [...]
Nlrp10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050252NACHT, LRR and PYD domains-containing protein 10; Inhibits autoprocessing of CASP1, CASP1-dependent IL1B secretion, PYCARD aggregation and PYCARD-mediated apoptosis but not apoptosis induced by F [...]
Nags protein networkhttps://string-db.org/network/10090.ENSMUSP00000050258N-acetylglutamate synthase conserved domain form; Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate syn [...]
Triml1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050267Probable E3 ubiquitin-protein ligase TRIML1; Probable E3 ubiquitin-protein ligase which plays an important role in blastocyst development. Involved in progression of blastocyst stage and subseque [...]
Gas2l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050275GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plu [...]
Tas2r119 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050277Taste receptor type 2 member 119; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calc [...]
Orai3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050279Protein orai-3; Key regulator or component of store-operated Ca(2+) channel and transcription factor NFAT nuclear import.
Eif5a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050289Eukaryotic translation initiation factor 5A-2; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of deca [...]
Ptges3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050292Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localiz [...]
Cradd protein networkhttps://string-db.org/network/10090.ENSMUSP00000050295Death domain-containing protein CRADD; Adapter protein that associates with PIDD1 and the caspase CASP2 to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis. Also recruits [...]
Cnpy3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050309Protein canopy homolog 3; Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticu [...]
Pilra protein networkhttps://string-db.org/network/10090.ENSMUSP00000050313Paired immunoglobulin-like type 2 receptor alpha; Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. Re [...]
Duox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050314Dual oxidase 2.
Slc25a47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050329Solute carrier family 25 member 47; Uncoupling protein which may catalyze the physiological 'proton leak' in liver; Belongs to the mitochondrial carrier (TC 2.A.29) family.
Gimap9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050330GTPase IMAP family member 9.
Ckap4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050336Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF.
Runx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050353Runt-related transcription factor 3; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the cor [...]
Pcdhb12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050357Protocadherin beta 12.
Selenov protein networkhttps://string-db.org/network/10090.ENSMUSP00000050372Selenoprotein V.
Sfn protein networkhttps://string-db.org/network/10090.ENSMUSP0000005037414-3-3 protein sigma; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognit [...]
Actrt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050377Actin-related protein T2.
Rnf149 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050388E3 ubiquitin-protein ligase RNF149; E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation.
Prss32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050389Protease, serine 32; Belongs to the peptidase S1 family.
Pus10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050395Putative tRNA pseudouridine synthase Pus10; Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formatio [...]
Uckl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050398Uridine-cytidine kinase-like 1; May contribute to UTP accumulation needed for blast transformation and proliferation.
Paip2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000050404Polyadenylate-binding protein-interacting protein 2B; Inhibits translation of capped and polyadenylated mRNAs by displacing PABPC1 from the poly(A) tail. Belongs to the PAIP2 family.
Cmya5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050408Cardiomyopathy-associated protein 5; May serve as an anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) via binding to PRKAR2A. May attenuate calcineurin a [...]
S1pr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050412Sphingosine 1-phosphate receptor 4; Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of [...]
Mettl21a protein networkhttps://string-db.org/network/10090.ENSMUSP00000050424Protein N-lysine methyltransferase METTL21A; Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo t [...]
Myct1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050430Myc target protein 1; May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpressio [...]
Foxe3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050445Forkhead box protein E3; Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle. During lens development, controls the ratio [...]
Irgm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050446Immunity-related GTPase family M protein 1; Putative GTPase which is required for IFNG-mediated clearance of acute protozoan and bacterial infections. Functions in innate immune response probably [...]
Tmem198b protein networkhttps://string-db.org/network/10090.ENSMUSP00000050451Transmembrane protein 198b.
Ush2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000050454Usherin; Involved in hearing and vision as member of the USH2 complex. In the inner ear, required for the maintenance of hair bundle ankle formation, which connects growing stereocilia in develop [...]
Rbm12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050461RNA-binding protein 12.
Cyp2j9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050464Cytochrome P450, family 2, subfamily j, polypeptide 9; Belongs to the cytochrome P450 family.
4933430I17Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000050465RIKEN cDNA 4933430I17 gene.
C1ql1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050469C1q-related factor; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.
Cyp4f14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050478Leukotriene-B4 omega-hydroxylase 3; Cytochromes P450 are a group of heme-thiolate monooxygenases. Catalyzes the omega-hydroxylation of LTB4 (By similarity).
Neurog1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050484Neurogenin-1; Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromati [...]
Lin28a protein networkhttps://string-db.org/network/10090.ENSMUSP00000050488Protein lin-28 homolog A; RNA-binding protein that inhibits processing of pre-let-7 miRNAs and regulates translation of mRNAs that control developmental timing, pluripotency and metabolism. Seems [...]
Sgsm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050496Small G protein signaling modulator 2; Possesses GTPase activator activity towards RAB32, RAB33B and RAB38. Regulates the trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosome [...]
Epx protein networkhttps://string-db.org/network/10090.ENSMUSP00000050497Eosinophil peroxidase heavy chain; Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils; Belongs to the peroxidase family. XPO subfamily.
Spata3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050509Spermatogenesis-associated protein 3.
Bhlha9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050516Class A basic helix-loop-helix protein 9; Transcription factor, which play a role in limb development. Is an essential player in the regulatory network governing transcription of genes implicated [...]
Fam167b protein networkhttps://string-db.org/network/10090.ENSMUSP00000050531Protein FAM167B; Belongs to the FAM167 (SEC) family.
Wdr89 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050532WD repeat-containing protein 89.
Adamts19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050535A disintegrin and metalloproteinase with thrombospondin motifs 19.
Ccer1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050554Coiled-coil domain-containing glutamate-rich protein 1.
Snai1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050581Zinc finger protein SNAI1; Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Bi [...]
Ccdc63 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050582Coiled-coil domain-containing protein 63; Plays a role in spermiogenesis. Involved in the elongation of flagella and the formation of sperm heads.
Kndc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050586Kinase non-catalytic C-lobe domain-containing protein 1; RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pa [...]
Ercc6l protein networkhttps://string-db.org/network/10090.ENSMUSP00000050592DNA excision repair protein ERCC-6-like; DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetocho [...]
Cep112 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050597Centrosomal protein of 112 kDa.
4930539E08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000050646Protein BNIP5.
Pigv protein networkhttps://string-db.org/network/10090.ENSMUSP00000050647GPI mannosyltransferase 2; Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI [...]
Ccnq protein networkhttps://string-db.org/network/10090.ENSMUSP00000050658Cyclin-Q; Activating cyclin for the cyclin-associated kinase CDK10. Belongs to the cyclin family. Cyclin-like FAM58 subfamily.
Lce3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000050666Late cornified envelope 3C.
Kcna3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050680Potassium voltage-gated channel subfamily A member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the [...]
Patz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050684POZ (BTB) and AT hook-containing zinc finger 1.
Kctd19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050687BTB/POZ domain-containing protein KCTD19.
Arf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050689ADP-ribosylation factor 3; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may mo [...]
Efnb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050716Ephrin-B1 intracellular domain; Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, [...]
Adam24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050727Disintegrin and metalloproteinase domain-containing protein 24; Plasma membrane protease present on mature sperm that may be involved in sperm function during epididymal maturation and/or fertili [...]
Zfp81 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050728Zinc finger protein 81.
Tmem18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050729Transmembrane protein 18; Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-s [...]
Svop protein networkhttps://string-db.org/network/10090.ENSMUSP00000050730Synaptic vesicle 2-related protein.
Apol7c protein networkhttps://string-db.org/network/10090.ENSMUSP00000050745Apolipoprotein L 7c.
Zfp867 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050746Zinc finger protein 867.
Peg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050750Paternally-expressed gene 3 protein; Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts sy [...]
Polr2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000050771DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and cataly [...]
Mapk8ip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050773C-Jun-amino-terminal kinase-interacting protein 1; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK c [...]
Supt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050783SPT3, SAGA and STAGA complex component.
Phkb protein networkhttps://string-db.org/network/10090.ENSMUSP00000050788Phosphorylase b kinase regulatory subunit beta; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory uni [...]
Pabpc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050792Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
Zfp235 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050803Zinc finger protein 235.
Epha10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050810Ephrin type-A receptor 10; Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5 (By similarity).
Igbp1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000050818Immunoglobulin-binding protein 1b; Associated to surface IgM-receptor; may be involved in signal transduction (By similarity). May be involved in regulation of the catalytic activity of type 2A-r [...]
Zfp36l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050820mRNA decay activator protein ZFP36L2; Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail remov [...]
Cyp20a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050823Cytochrome P450 20A1; Belongs to the cytochrome P450 family.
Rlf protein networkhttps://string-db.org/network/10090.ENSMUSP00000050825Rearranged L-myc fusion sequence.
Sned1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050832Sushi, nidogen and EGF-like domain-containing protein 1.
Wfdc12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050836WAP four-disulfide core domain protein 12; Antibacterial protein which inhibits the growth of E.coli and S.aureus. Putative acid-stable proteinase inhibitor.
Zfp367 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050854Zinc finger protein 367; Transcriptional activator. Isoform 1 may be involved in transcriptional activation of erythroid genes (By similarity).
Tmem37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050862Voltage-dependent calcium channel gamma-like subunit; Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity). Modulates calcium current when coexpressed with CA [...]
Fam228b protein networkhttps://string-db.org/network/10090.ENSMUSP00000050881Protein FAM228B.
Slfnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050896Schlafen-like protein 1.
S1pr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050897Sphingosine 1-phosphate receptor 1; G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G prot [...]
Sprr2f protein networkhttps://string-db.org/network/10090.ENSMUSP00000050902Small proline-rich protein 2F; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane [...]
Mettl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050907Methyltransferase-like protein 5; Probable methyltransferase.
Nkx2-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050933Homeobox protein Nkx-2.3; Transcriptional regulator essential for normal development and functions of the small intestine and spleen. Activates directly MADCAM1 expression. Required for homing of [...]
Exosc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050940Exosome complex component RRP41; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrad [...]
Pyurf protein networkhttps://string-db.org/network/10090.ENSMUSP00000050958Protein preY, mitochondrial.
Akap4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050962A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility.
Zfp719 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050968Zinc finger protein 719.
Zswim3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050970Zinc finger SWIM domain-containing protein 3.
Trex1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050971Three-prime repair exonuclease 1; Major cellular 3'-to-5' DNA exonuclease which digests single- stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini. Prevents cell-intr [...]
Crebzf protein networkhttps://string-db.org/network/10090.ENSMUSP00000050972CREB/ATF bZIP transcription factor; Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. A [...]
Slc35e4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050978Solute carrier family 35 member E4; Putative transporter; Belongs to the TPT transporter family. SLC35E subfamily.
Man1c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050979alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
Rpp38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050992Ribonuclease P protein subunit p38; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclea [...]
Ccdc57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050996Coiled-coil domain-containing protein 57.
Slc26a11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000050999Sodium-independent sulfate anion transporter; Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high end [...]
Hoxc12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051003Homeobox protein Hox-C12; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posteri [...]
Tuba1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000051033Detyrosinated tubulin alpha-1C chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site [...]
D1Ertd622e protein networkhttps://string-db.org/network/10090.ENSMUSP00000051034Macrophage immunometabolism regulator; Regulates the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages. The regulation of macr [...]
Tssk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051035Testis-specific serine/threonine-protein kinase 2; Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-281' of TSKS and SPAG16. Involved in [...]
Pcdhb7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051041Protocadherin beta 7.
Bag5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051049BAG family molecular chaperone regulator 5; May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. Inhibits both auto-ubiquiti [...]
Zfp473 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051069Zinc finger protein 473 homolog; Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processi [...]
Adgrg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051079Adhesion G protein-coupled receptor G3; Orphan receptor that regulates migration of lymphatic endothelial cells via the small GTPases RhoA and CDC42 (By similarity). Regulates B-cell development. [...]
Eml6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051080Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; Belongs to the WD repeat EMAP fam [...]
Sstr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051085Somatostatin receptor type 5; Receptor for somatostatin-28. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SS [...]
Rfx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051107Transcription factor RFX4; [Isoform 1]: Transcription factor that plays a role in early brain development. May activate transcription by interacting directly with the X-box. May activate transcri [...]
Hes5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051118Transcription factor HES-5; Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator.
Gm10037 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051123Predicted gene 10037.
Oxtr protein networkhttps://string-db.org/network/10090.ENSMUSP00000051132Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein c [...]
Meox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051158Homeobox protein MOX-1; Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome [...]
Iqub protein networkhttps://string-db.org/network/10090.ENSMUSP00000051177IQ and ubiquitin-like domain-containing protein; May play roles in cilia formation and/or maintenance.
Prss48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051199Serine protease 48.
Spem2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051204Uncharacterized protein SPEM2.
Fam180a protein networkhttps://string-db.org/network/10090.ENSMUSP00000051206Protein FAM180A.
Epop protein networkhttps://string-db.org/network/10090.ENSMUSP00000051211Elongin BC and Polycomb repressive complex 2-associated protein; Scaffold protein that serves as a bridging partner between the PRC2/EED-EZH2 complex and the elongin BC complex: required to fine- [...]
Hk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051215Hexokinase-3; Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D- fructose 6-phosphate, respectively). Mediates the init [...]
Styxl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051216Serine/threonine/tyrosine-interacting-like 1.
Msl3l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051220MSL3-like 2.
Atp5k protein networkhttps://string-db.org/network/10090.ENSMUSP00000051222ATP synthase subunit e, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
Ywhag protein networkhttps://string-db.org/network/10090.ENSMUSP0000005122314-3-3 protein gamma, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partn [...]
Pxdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051246PX domain-containing protein 1.
Vcpip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051248Deubiquitinating protein VCIP135; Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitiona [...]
Arxes2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051250Adipocyte-related X-chromosome expressed sequence 1; Plays a role in adipogenesis; Belongs to the SPCS3 family.
Serinc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051261Serine incorporator 4; Incorporates a polar amino acid serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids; Belongs to the TDE1 [...]
Vps35l protein networkhttps://string-db.org/network/10090.ENSMUSP00000051263VPS35 endosomal protein sorting factor-like; Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and es [...]
Echdc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051268Enoyl-CoA hydratase domain-containing protein 2, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.
Kcnk7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051278Potassium channel subfamily K member 7; Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as [...]
Olfr544 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051280Olfactory receptor.
Pip5kl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051282Phosphatidylinositol 4-phosphate 5-kinase-like protein 1; May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4 [...]
Clptm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051293Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development.
Ndnf protein networkhttps://string-db.org/network/10090.ENSMUSP00000051297Protein NDNF; Promotes neuron migration, growth and survival as well as neurite outgrowth (By similarity). Promotes matrix assembly and cell adhesiveness. Promotes endothelial cell survival, vess [...]
Kctd21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051316BTB/POZ domain-containing protein KCTD21; Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal [...]
Axin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051331Axin-2; Inhibitor of the Wnt signaling pathway. Down-regulates beta- catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B.
Acot10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051333Acyl-coenzyme A thioesterase 10, mitochondrial; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing th [...]
Zfpm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051335Zinc finger protein ZFPM2; Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential dur [...]
Ltb4r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051368Leukotriene B4 receptor 1; Receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response; Belongs to the G-protein coupled receptor 1 family.
Fam13c protein networkhttps://string-db.org/network/10090.ENSMUSP00000051375Protein FAM13C; Belongs to the FAM13 family.
Neurod4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051379Neurogenic differentiation factor 4; Probably acts as a transcriptional activator. Mediates neuronal differentiation. Required for the regulation of amacrine cell fate specification in the retina [...]
Akap8l protein networkhttps://string-db.org/network/10090.ENSMUSP00000051389A-kinase anchor protein 8-like; Could play a role in constitutive transport element (CTE)- mediated gene expression by association with DHX9. Increases CTE- dependent nuclear unspliced mRNA expor [...]
Rln3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051392Relaxin-3 A chain; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 and relaxin-3 receptor-2 (By similarity); Belongs to the insulin family.
Palm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051396Paralemmin-3; ATP-binding protein, which may act as a adapter in the Toll- like receptor (TLR) signaling; Belongs to the paralemmin family.
Morn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051408MORN repeat-containing protein 2; Might have a role in spermatogenesis.
Tmem17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051414Transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of tran [...]
Gpr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051417G-protein coupled receptor 1; Receptor for the inflammation-associated leukocyte chemoattractant chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation (By similar [...]
H2ax protein networkhttps://string-db.org/network/10090.ENSMUSP00000051432Histone H2AX; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineri [...]
Pthlh protein networkhttps://string-db.org/network/10090.ENSMUSP00000051433Parathyroid hormone-related protein; Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calc [...]
Tmem136 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051435TLC domain-containing protein 5.
Pisd protein networkhttps://string-db.org/network/10090.ENSMUSP00000051438Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid meta [...]
Agmo protein networkhttps://string-db.org/network/10090.ENSMUSP00000051441Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes (By similarity).
4930503B20Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000051453RIKEN cDNA 4930503B20 gene.
Slurp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051457Secreted Ly-6/uPAR domain-containing protein 2; Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors. May regulate keratinocytes proliferation, dif [...]
Plekha4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051468Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides.
Aff4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051479AF4/FMR2 family member 4; Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausin [...]
Neurl1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000051481E3 ubiquitin-protein ligase NEURL1B; E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands.
Hpcal4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051487Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; Belongs to the recoverin family.
Setx protein networkhttps://string-db.org/network/10090.ENSMUSP00000051492Probable helicase senataxin; Probable RNA/DNA helicase involved in diverse aspects of RNA metabolism and genomic integrity. Plays a role in transcription regulation by its ability to modulate RNA [...]
Alkbh6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051515Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6; Probable dioxygenase that requires molecular oxygen, alpha- ketoglutarate and iron; Belongs to the alkB family.
Vsig4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051521V-set and immunoglobulin domain-containing 4.
Stpg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051539Sperm-tail PG-rich repeat-containing protein 2.
Lrfn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051546Leucine-rich repeat and fibronectin type-III domain-containing protein 5; Cell adhesion molecule that mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgr [...]
Gm12794 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051550Predicted gene 12794.
Fscb protein networkhttps://string-db.org/network/10090.ENSMUSP00000051554Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium.
Sprr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051559Small proline-rich protein 4; Cross-linked envelope protein of keratinocytes. Involved in UV-induced cornification (By similarity).
Mcat protein networkhttps://string-db.org/network/10090.ENSMUSP00000051569Malonyl-CoA-acyl carrier protein transacylase, mitochondrial; Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondria [...]
Calhm6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051575Calcium homeostasis modulator protein 6; Pore-forming subunit of a voltage-gated ion channel. Belongs to the CALHM family.
Col9a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051579Collagen alpha-1(IX) chain; Structural component of hyaline cartilage and vitreous of the eye.
Rai2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051618Retinoic acid-induced protein 2.
Mapk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051619Mitogen-activated protein kinase 3; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which pla [...]
Mmgt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051621Membrane magnesium transporter 1; Mediates Mg(2+) transport.
A730049H05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000051623RIKEN cDNA A730049H05 gene.
Scn3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000051627Sodium channel subunit beta-3; Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its associa [...]
Olfr250 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051631Olfactory receptor.
Dact2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051638Dapper homolog 2; Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation [...]
Dnajc11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051643DnaJ homolog subfamily C member 11; Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane s [...]
Mblac2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051644Metallo-beta-lactamase domain-containing protein 2.
C1qtnf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051652Complement C1q tumor necrosis factor-related protein 2; Involved in the regulation of lipid metabolism in adipose tissue and liver.
Psmd8 protein networkhttps://string-db.org/network/10090.ENSMUSP0000005165726S proteasome non-ATPase regulatory subunit 8; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a k [...]
Zc2hc1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000051664Zinc finger C2HC domain-containing protein 1C; Belongs to the ZC2HC1 family.
Catsper4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051694Cation channel sperm-associated protein 4; Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a [...]
Asrgl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051709Isoaspartyl peptidase/L-asparaginase alpha chain; Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory ne [...]
Adig protein networkhttps://string-db.org/network/10090.ENSMUSP00000051732Adipogenin; Plays a role in stimulating adipocyte differentiation and development; Belongs to the adipogenin family.
Defb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051754Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Bind [...]
Ttc34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051782Tetratricopeptide repeat protein 34.
4930563M21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000051794RIKEN cDNA 4930563M21 gene.
Ensa protein networkhttps://string-db.org/network/10090.ENSMUSP00000051799Alpha-endosulfine; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with [...]
Ggnbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051800Gametogenetin-binding protein 1; Induces mitochondrial fragmentation, possibly by promoting DNM1L-dependent fission and may play a role in mitochondrial morphogenesis during spermatogenesis.
Gprin3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051805G protein-regulated inducer of neurite outgrowth 3; May be involved in neurite outgrowth.
Rictor protein networkhttps://string-db.org/network/10090.ENSMUSP00000051809Rapamycin-insensitive companion of mTOR; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mT [...]
Dnmt3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000051830DNA (cytosine-5)-methyltransferase 3B; Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coord [...]
Pptc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051838Protein phosphatase PTC7 homolog; Protein phosphatase which positively regulates biosynthesis of the ubiquinone, coenzyme Q (By similarity). Dephosphorylates the ubiquinone biosynthesis protein C [...]
Jrk protein networkhttps://string-db.org/network/10090.ENSMUSP00000051842Jerky protein; May bind DNA.
Ino80 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051845Chromatin-remodeling ATPase INO80; ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair. Binds DNA. As part o [...]
Kcnk13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051846Potassium channel subfamily K member 13; Potassium channel displaying weak inward rectification in symmetrical K(+) solution; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
Ccdc9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000051853Coiled-coil domain-containing protein 9B.
Zfp11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051861Zinc finger protein 11.
Atg9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000051864Autophagy-related protein 9B; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore [...]
Pmel protein networkhttps://string-db.org/network/10090.ENSMUSP00000051869Melanocyte protein PMEL; Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II m [...]
Pcare protein networkhttps://string-db.org/network/10090.ENSMUSP00000051871Photoreceptor cilium actin regulator; Plays an essential role for normal photoreceptor cell maintenance and vision.
Cldn8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051887Claudin-8; Tight-junction protein required for paracellular chloride transport in the kidney. Mediates recruitment of CLDN4 to tight junction in the kidney. Claudins play a major role in tight ju [...]
Gp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051895Platelet glycoprotein V; The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces [...]
Gas2l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051907GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracki [...]
Pate5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051917Prostate and testis-expressed 5.
Bst2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051921Bone marrow stromal antigen 2; IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to t [...]
Hectd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051922E3 ubiquitin-protein ligase HECTD3; E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targete [...]
Olfr147 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051933Olfactory receptor 147; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Bzw1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051935Basic leucine zipper and W2 domain-containing protein 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly; Belongs to the BZW family.
Rasd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051959Dexamethasone-induced Ras-related protein 1; Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65 (By similar [...]
Exoc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051965Exocyst complex component 4; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane; Belongs to the SEC8 family.
Tmem123 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051966Porimin; Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability; Belongs to the CD164 family.
Polr2k protein networkhttps://string-db.org/network/10090.ENSMUSP00000051968DNA-directed RNA polymerases I, II, and III subunit RPABC4; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Com [...]
Abra protein networkhttps://string-db.org/network/10090.ENSMUSP00000051973Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanis [...]
Zfp784 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051979Zinc finger protein 784; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Nkx3-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000051990Homeobox protein Nkx-3.2; Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric mor [...]
Krtap24-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052005Keratin-associated protein 24-1.
Prss38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052010Serine protease 38.
Ust protein networkhttps://string-db.org/network/10090.ENSMUSP00000052017Uronyl 2-sulfotransferase; Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weak [...]
Flnb protein networkhttps://string-db.org/network/10090.ENSMUSP00000052020Filamin-B; Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various [...]
H2al3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052025H2A histone family member L3.
Jaml protein networkhttps://string-db.org/network/10090.ENSMUSP00000052033Junctional adhesion molecule-like; Transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane recepto [...]
Akap17b protein networkhttps://string-db.org/network/10090.ENSMUSP00000052042A-kinase anchor protein 17B; Splice factor regulating alternative splice site selection for certain mRNA precursors.
Lrrc8e protein networkhttps://string-db.org/network/10090.ENSMUSP00000052055Volume-regulated anion channel subunit LRRC8E; Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cel [...]
Ankrd16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052056Ankyrin repeat domain-containing protein 16; Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role i [...]
Cdh20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052078Cadherin-20; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the [...]
Daam2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052085Disheveled-associated activator of morphogenesis 2; Key regulator of the Wnt signaling pathway, which is required for various processes during development, such as dorsal patterning, determinatio [...]
Actbl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052086Beta-actin-like protein 2; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin fa [...]
Pou3f3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052088POU domain, class 3, transcription factor 3; Transcription factor that acts synergistically with SOX11 and SOX4 (By similarity). Plays a role in neuronal development. Is implicated in an enhancer [...]
Catsperb protein networkhttps://string-db.org/network/10090.ENSMUSP00000052089Cation channel sperm-associated protein subunit beta; Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility wh [...]
Col26a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052095Collagen alpha-1(XXVI) chain.
Cdr2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000052096Cerebellar degeneration-related protein 2-like; Belongs to the CDR2 family.
Ttc7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000052107Tetratricopeptide repeat protein 7B; Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinosit [...]
Mis18bp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052109Mis18-binding protein 1; Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
Pcdhb18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052113Protocadherin beta-18; Potential calcium-dependent cell-adhesion protein.
Vmn1r45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052123Vomeronasal type-1 receptor 45; Putative pheromone receptor implicated in the regulation of social and reproductive behavior; Belongs to the G-protein coupled receptor 1 family.
Ssc5d protein networkhttps://string-db.org/network/10090.ENSMUSP00000052126Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D; Binds to extracellular matrix proteins. Binds to pathogen- associated molecular patterns (PAMPs) present on the cell wall [...]
Lor protein networkhttps://string-db.org/network/10090.ENSMUSP00000052128Loricrin; Major keratinocyte cell envelope protein.
Tmem215 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052129Transmembrane protein 215.
Ly6g5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000052133Lymphocyte antigen 6 complex locus protein G5b.
Car7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052136Carbonic anhydrase 7; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family.
Csrnp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052144Cysteine/serine-rich nuclear protein 2; Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May play a role in apoptosis. Belongs to the AXUD1 family.
Lancl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052146LanC-like protein 2; Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. Belongs to the LanC-like protein family.
Utp14b protein networkhttps://string-db.org/network/10090.ENSMUSP00000052149U3 small nucleolar RNA-associated protein 14 homolog B; Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis; Belong [...]
Olfr1284 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052153Olfactory receptor.
Prr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052166Proline-rich protein 3.
Terf2ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000052170Telomeric repeat-binding factor 2-interacting protein 1; Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protecti [...]
Slc38a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052172Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of t [...]
Lrrc28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052177Leucine-rich repeat-containing protein 28.
Bbs12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052179Bardet-Biedl syndrome 12 protein homolog; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. As part [...]
Gpr37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052185Prosaposin receptor GPR37; Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade (By similarity).
Zfp770 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052194Zinc finger protein 770; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Foxc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052196Forkhead box protein C1; DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin developm [...]
Zfp260 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052200Zinc finger protein 260; Transcription factor that acts as a cardiac regulator and an effector of alpha1-adrenergic signaling. Binds to PE response elements (PERE) present in the promoter of gene [...]
Frmd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052202FERM domain-containing protein 6.
Fam124b protein networkhttps://string-db.org/network/10090.ENSMUSP00000052208Protein FAM124B; Belongs to the FAM124 family.
Bcl2l15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052210Bcl-2-like protein 15.
Gk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052226Glycerol kinase 2; Key enzyme in the regulation of glycerol uptake and metabolism; Belongs to the FGGY kinase family.
Mrgprb8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052230Mas-related G-protein coupled receptor member B8; Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sen [...]
Tctex1d4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052243Tctex1 domain-containing protein 4.
Kcne1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052248Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates t [...]
Clrn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052254Clarin-1; May have a role in the excitatory ribbon synapse junctions between hair cells and cochlear ganglion cells and presumably also in analogous synapses within the retina.
Amfr protein networkhttps://string-db.org/network/10090.ENSMUSP00000052258E3 ubiquitin-protein ligase AMFR; E3 ubiquitin-protein ligase that mediates the polyubiquitination of a number of proteins such as CD3D, CYP3A4, CFTR and APOB for proteasomal degradation. Compone [...]
Vamp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052262Vesicle-associated membrane protein 7; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. [...]
Catsperg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052285Cation channel sperm-associated protein subunit gamma 2; Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility [...]
Ccdc121 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052294Coiled-coil domain-containing 121.
Chrnb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052297Neuronal acetylcholine receptor subunit beta-3; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-cond [...]
Bptf protein networkhttps://string-db.org/network/10090.ENSMUSP00000052303Bromodomain PHD finger transcription factor.
Plppr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052306Phospholipid phosphatase-related protein type 4; Hydrolyzes lysophosphatidic acid (LPA). Facilitates axonal outgrowth during development and regenerative sprouting. In the outgrowing axons acts a [...]
Klf17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052316Krueppel-like factor 17; Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and me [...]
Tigd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052320Tigger transposable element-derived protein 4.
Ssu2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052328Protein SSUH2 homolog; Plays a role in odontogenesis.
Csl protein networkhttps://string-db.org/network/10090.ENSMUSP00000052373Citrate synthase; Belongs to the citrate synthase family.
Gm5105 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052388Predicted gene 5105.
Gpr183 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052404G-protein coupled receptor 183; G-protein coupled receptor expressed in lymphocytes that acts as a chemotactic receptor for B-cells, T-cells, splenic dendritic cells, monocytes/macrophages and as [...]
Olfr215 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052425Olfactory receptor.
Olfr1325 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052441Olfactory receptor.
Cxcr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052444C-X-C chemokine receptor type 3; Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrim [...]
Thnsl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052452Threonine synthase-like 1.
Scgb2b24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052456Secretoglobin family 2B member 24; Belongs to the secretoglobin family.
Bend7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052458BEN domain-containing protein 7.
Wdr36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052465WD repeat domain 36.
Upk1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000052469Uroplakin-1b; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal blad [...]
Tmem132e protein networkhttps://string-db.org/network/10090.ENSMUSP00000052484Transmembrane protein 132E; Required for normal inner ear hair cell function and hearing.
Hoxb8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052496Homeobox protein Hox-B8; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Frrs1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000052507DOMON domain-containing protein FRRS1L; Important modulator of glutamate signaling pathway.
Hsf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052508Heat shock factor protein 3; DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription of non-classical heat-shock genes such as PDZD2 and PROM2. [...]
Ankrd46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052521Ankyrin repeat domain-containing protein 46.
Pik3r6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052522Phosphoinositide 3-kinase regulatory subunit 6; Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 he [...]
Pdcd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052523Programmed cell death protein 2; May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation.
Zadh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052544Prostaglandin reductase-3; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto [...]
Nr1h5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052557Nuclear receptor subfamily 1, group H, member 5.
Dlx5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052559Homeobox protein DLX-5; Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulat [...]
Lrrk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052584Leucine-rich repeat serine/threonine-protein kinase 2; Serine/threonine-protein kinase which phosphorylates a broad range of proteins involved in multiple processes such as neuronal plasticity, a [...]
Tprg protein networkhttps://string-db.org/network/10090.ENSMUSP00000052585Tumor protein p63-regulated gene 1 protein.
Defb29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052589Beta-defensin 29; Has antibacterial activity.
Tbx20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052591T-box transcription factor TBX20; Acts as a transcriptional activator and repressor required for cardiac development and may have key roles in the maintenance of functional and structural phenoty [...]
Gsto2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052592Glutathione S-transferase omega-2; Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Pa [...]
Ly6k protein networkhttps://string-db.org/network/10090.ENSMUSP00000052599Lymphocyte antigen 6K; Required for sperm migration into the oviduct and male fertility by controlling binding of sperm to zona pellucida. May play a role in cell growth (By similarity).
Ffar2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052600Free fatty acid receptor 2; G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulatio [...]
Wdfy3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052607WD repeat and FYVE domain-containing protein 3; Required for selective macroautophagy (aggrephagy). Acts as an adapter protein by linking specific proteins destined for degradation to the core au [...]
Pard6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000052619Partitioning defective 6 homolog beta; Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Associ [...]
Stxbp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052639Syntaxin-binding protein 6; Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis.
Zfp646 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052641Zinc finger protein 646; May be involved in transcriptional regulation.
Tmem67 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052644Meckelin; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. Involved in centrosome migration to the apical cell s [...]
Ar protein networkhttps://string-db.org/network/10090.ENSMUSP00000052648Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target ti [...]
Pop1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052654Processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae).
Adam5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052661Disintegrin and metalloproteinase domain-containing protein 5; This is a non catalytic metalloprotease-like protein. May play a role in sperm-egg fusion (By similarity).
Skint9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052670Selection and upkeep of intraepithelial T-cells protein 9; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus; Belongs to the SKINT family.
Olfr523 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052678Olfactory receptor.
Olfr982 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052705Olfactory receptor MOR223-4.
Fbxl13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052716Dynein regulatory complex subunit 6; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the dis [...]
Zbtb39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052717Zinc finger and BTB domain-containing 39.
Dcaf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052755DDB1- and CUL4-associated factor 5; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Itsn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052758Intersectin-2; Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs [...]
1110012L19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000052765Uncharacterized protein CXorf40 homolog.
Eps8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052776Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its asso [...]
Pik3ap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052777Phosphoinositide 3-kinase adapter protein 1; Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3- kinase (PI3K)-Akt signa [...]
Nkx1-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052778NK1 transcription factor-related protein 2; May function in cell specification, particularly in the CNS; Belongs to the NK-1 homeobox family.
Frat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052788GSK-3-binding protein FRAT2; Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3; Belongs to the GSK-3-binding protein family.
5430402E10Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000052804RIKEN cDNA 5430402E10 gene; Belongs to the calycin superfamily. Lipocalin family.
Klri2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052805Killer cell lectin-like receptor subfamily I member 2; Lectin-like receptor for natural killer (NK) cells. Heterodimer formation with KLRE1 mediates NK cell cytolytic activity.
Antxrl protein networkhttps://string-db.org/network/10090.ENSMUSP00000052816Anthrax toxin receptor-like.
Fam78a protein networkhttps://string-db.org/network/10090.ENSMUSP00000052826Protein FAM78A; Belongs to the FAM78 family.
Pigm protein networkhttps://string-db.org/network/10090.ENSMUSP00000052838GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly [...]
Slc25a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052849Solute carrier family 25 (Mitochondrial carrier, Ornithine transporter) member 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.
Rnf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052856RING-box protein 2; Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins [...]
Nfib protein networkhttps://string-db.org/network/10090.ENSMUSP00000052863Nuclear factor 1 B-type; Transcriptional activator of GFAP, essential for proper brain development. Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellul [...]
Pgp protein networkhttps://string-db.org/network/10090.ENSMUSP00000052866Glycerol-3-phosphate phosphatase; Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3- phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic inte [...]
Mblac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052869Metallo-beta-lactamase domain-containing protein 1.
Creg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052871Protein CREG2; Belongs to the CREG family.
Fasn protein networkhttps://string-db.org/network/10090.ENSMUSP000000528723-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has [...]
Fpr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052894fMet-Leu-Phe receptor; High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular c [...]
Epm2aip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052904EPM2A-interacting protein 1.
Eny2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052905Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histon [...]
Micos13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052908MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner mem [...]
Pdia6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052912Protein disulfide-isomerase A6; May function as a chaperone that inhibits aggregation of misfolded proteins. Negatively regulates the unfolded protein response (UPR) through binding to UPR sensor [...]
Bend6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052919BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-ren [...]
Tvp23a protein networkhttps://string-db.org/network/10090.ENSMUSP00000052922Golgi apparatus membrane protein TVP23 homolog.
Rhox11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052929Reproductive homeobox on X chromosome 11.
Sugt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052942Protein SGT1 homolog; May play a role in ubiquitination and subsequent proteasomal degradation of target proteins.
Zfp764 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052944Zinc finger protein 764.
Lenep protein networkhttps://string-db.org/network/10090.ENSMUSP00000052968Lens epithelial cell protein LEP503.
Vmn2r13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052977Vomeronasal 2, receptor 13.
Cdc42se1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000052986CDC42 small effector protein 1; Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape ch [...]
Cyp8b1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000529897-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha- dihydrox [...]
4930402K13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000053000RIKEN cDNA 4930402K13 gene.
Zfp691 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053013Zinc finger protein 691; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Klhl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053023Kelch-like protein 6; Involved in B-lymphocyte antigen receptor signaling and germinal center formation.
Fut4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053027Alpha-(1,3)-fucosyltransferase 4; May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
Mrps7 protein networkhttps://string-db.org/network/10090.ENSMUSP0000005303328S ribosomal protein S7, mitochondrial; Belongs to the universal ribosomal protein uS7 family.
1700024P04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000053046Histone H2B subacrosomal variant; May act as an acrosome-nuclear docking protein in sperm.
Ormdl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053056ORM1-like protein 3; Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling (By similarity).
Tnp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053078Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it [...]
Spata21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053080Spermatogenesis-associated protein 21; Involved in the differentiation of haploid spermatids.
Lrrc75b protein networkhttps://string-db.org/network/10090.ENSMUSP00000053085Leucine-rich repeat-containing protein 75B; Belongs to the LRRC75 family.
Mtnr1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000053086Melatonin receptor type 1B; High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By si [...]
Ppp3ca protein networkhttps://string-db.org/network/10090.ENSMUSP00000053101Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracel [...]
Odf3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000053112Outer dense fiber protein 3B; Belongs to the ODF3 family.
Rtel1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053120Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase [...]
Pofut1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053122GDP-fucose protein O-fucosyltransferase 1; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence [...]
Lrrc4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000053123Leucine-rich repeat-containing protein 4B; Synaptic adhesion protein. Regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation [...]
Baiap2l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053129Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganiz [...]
Uqcrq protein networkhttps://string-db.org/network/10090.ENSMUSP00000053145Cytochrome b-c1 complex subunit 8; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which dr [...]
Phf11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000053146PHD finger protein 11A.
Barhl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053147BarH-like 1 homeobox protein; Belongs to the BAR homeobox family.
Scml4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053157Sex comb on midleg-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state [...]
Sdf4 protein networkhttps://string-db.org/network/10090.ENSMUSP0000005317545 kDa calcium-binding protein; May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
Tcf21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053178Transcription factor 21; Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. May be involved in t [...]
Slc30a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053181Zinc transporter 10; Plays a pivotal role in manganese transport. Manganese is an essential cation for the function of several enzymes, including some crucially important for the metabolism of ne [...]
Cfap69 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053206Cilia- and flagella-associated protein 69; Cilium- and flagellum-associated protein. In the olfactory epithelium, regulates the speed of activation and termination of the odor response and thus c [...]
Ccdc84 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053216Coiled-coil domain-containing protein 84.
Slc16a13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053218Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. [...]
Ddi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053223Protein DDI1 homolog 1; Probable aspartic protease (By similarity). Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2. Required, with DDI2, [...]
Stard13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053232StAR-related lipid transfer protein 13; May function as a GTPase-activating protein.
Neurl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053235Neuralized-like protein 4; Promotes CCP110 ubiquitination and proteasome-dependent degradation. By counteracting accumulation of CP110, maintains normal centriolar homeostasis and preventing form [...]
Wfikkn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053238WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2; Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metallopro [...]
Lipa protein networkhttps://string-db.org/network/10090.ENSMUSP00000053270Lysosomal acid lipase/cholesteryl ester hydrolase; Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor- mediated endocytosis [...]
Lypd10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053275Ly6/PLAUR domain-containing 10.
Onecut3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053288One cut domain family member 3; Transcriptional activator. Binds the consensus DNA sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR.
Foxl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053297Forkhead box protein L2; Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Pr [...]
BC024139 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053305cDNA sequence BC024139.
Olfr1030 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053309Olfactory receptor 1030; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Krtap1-5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053312Keratin-associated protein 1-5.
Slc25a46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053325Solute carrier family 25 member 46; May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission.
Pcdhb19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053326Protocadherin beta 19.
Lysmd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053341LysM and putative peptidoglycan-binding domain-containing protein 4.
Emx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053361Homeobox protein EMX2; Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations [...]
Pxt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053366Peroxisomal testis-specific protein 1.
Cltb protein networkhttps://string-db.org/network/10090.ENSMUSP00000053371Clathrin light chain B; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
Trim3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053384Tripartite motif-containing protein 3; Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recyc [...]
Rasl11b protein networkhttps://string-db.org/network/10090.ENSMUSP00000053389Ras-like protein family member 11B.
Il1f9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053391Interleukin-36 gamma; Functions as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2/IL1RL2. Part of the IL-36 signaling system that is thought to be present [...]
S1pr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053394Sphingosine 1-phosphate receptor 2; Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P) (By similarity). S1P is a bioactive lysophospholipid that elicits diverse physiological effects [...]
Ly6g2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053396Lymphocyte antigen 6 complex, locus G2.
Zfp319 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053397Zinc finger protein 319; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Ptprcap protein networkhttps://string-db.org/network/10090.ENSMUSP00000053412Protein tyrosine phosphatase receptor type C-associated protein.
Cldn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053420Claudin-4; Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the k [...]
Vat1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000053431Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Fam186a protein networkhttps://string-db.org/network/10090.ENSMUSP00000053434Protein FAM186A.
Grpel2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053440GrpE protein homolog 2, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mit [...]
Prl2c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053446Prolactin family 2, subfamily c, member 1.
Lipi protein networkhttps://string-db.org/network/10090.ENSMUSP00000053447Lipase, member I.
Fubp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053474Far upstream element (FUSE)-binding protein 3.
Hic1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053483Hypermethylated in cancer 1 protein; Transcriptional repressor. Recognizes and binds to the consensus sequence '5-[CG]NG[CG]GGGCA[CA]CC-3'. May act as a tumor suppressor. May be involved in devel [...]
BB014433 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053487Expressed sequence BB014433.
Cxcr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053489C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involv [...]
Gstz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053540Maleylacetoacetate isomerase; Probable bifunctional enzyme showing minimal glutathione- conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2- oxa-1, 3-diazole and maleylacetoaceta [...]
Meaf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053543Chromatin modification-related protein MEAF6; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of [...]
Bicdl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053547BICD family-like cargo adapter 1; Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by contro [...]
Fzd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053551Frizzled-9; Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulati [...]
Plcxd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053553PI-PLC X domain-containing protein 3.
Abhd12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053558Lysophosphatidylserine lipase ABHD12; Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neur [...]
Zfp526 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053567Zinc finger protein 526; May be involved in transcriptional regulation.
Kcnk12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053595Potassium channel, subfamily K, member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
Lrrc38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053597Leucine-rich repeat-containing protein 38; Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marke [...]
Tk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053616Thymidine kinase 2, mitochondrial; Phosphorylates thymidine, deoxycytidine, and deoxyuridine in the mitochondrial matrix. In non-replicating cells, where cytosolic dNTP synthesis is down-regulate [...]
Aplnr protein networkhttps://string-db.org/network/10090.ENSMUSP00000053638Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early d [...]
Zfp282 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053643Zinc finger protein 282.
Sptssa protein networkhttps://string-db.org/network/10090.ENSMUSP00000053671Serine palmitoyltransferase small subunit A; Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrat [...]
Pygo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053672Pygopus 2.
Hexim2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053678Protein HEXIM2; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP com [...]
Sh2d7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053690SH2 domain-containing protein 7.
Unc80 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053692Protein unc-80 homolog; Component of the NALCN sodium channel complex, required for channel regulation. This complex is a cation channel activated by neuropeptides substance P, neurotensin, and e [...]
Tas2r118 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053700Taste receptor type 2 member 16; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calci [...]
Krtap4-7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053711Keratin associated protein 4-7.
Coa4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053727Cytochrome c oxidase assembly factor 4 homolog, mitochondrial; Putative COX assembly factor; Belongs to the COA4 family.
Marveld1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053733MARVEL domain-containing protein 1; Microtubule-associated protein that exhibits cell cycle- dependent localization and can inhibit cell proliferation and migration.
Pcsk6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053742Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family.
Sprr1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000053751Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transg [...]
Trpv3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053755Transient receptor potential cation channel subfamily V member 3; Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and s [...]
Zfp629 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053760Zinc finger protein 629; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Exoc3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000053766Exocyst complex component 3-like protein; As part of the exocyst, may play a role in regulated exocytosis of insulin granules; Belongs to the SEC6 family.
Gapt protein networkhttps://string-db.org/network/10090.ENSMUSP00000053775Protein GAPT; Negatively regulates B-cell proliferation following stimulation through the B-cell receptor. May play an important role in maintenance of marginal zone (MZ) B-cells.
Tmem202 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053782Transmembrane protein 202.
Ankrd13d protein networkhttps://string-db.org/network/10090.ENSMUSP00000053783Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regul [...]
Fbxw13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053786F-box and WD-40 domain protein 13.
Pomk protein networkhttps://string-db.org/network/10090.ENSMUSP00000053802Protein O-mannose kinase; Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-ace [...]
Nqo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053809Ribosyldihydronicotinamide dehydrogenase [quinone]; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathwa [...]
Krtap4-13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053810Keratin associated protein 4-13.
Gnat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053818Guanine nucleotide-binding protein G(t) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Tra [...]
Cd200r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053822Cell surface glycoprotein CD200 receptor 1; Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules includin [...]
Tmem229b protein networkhttps://string-db.org/network/10090.ENSMUSP00000053835Transmembrane protein 229B.
Gpr85 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053837Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Dnaja3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053842DnaJ homolog subfamily A member 3, mitochondrial; Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria [...]
Sprr2h protein networkhttps://string-db.org/network/10090.ENSMUSP00000053849Small proline-rich protein 2H; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane [...]
Tmem186 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053862Transmembrane protein 186.
Elfn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053869Protein ELFN1; Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitator [...]
Nipa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053871Magnesium transporter NIPA1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+); Belon [...]
Fam120a protein networkhttps://string-db.org/network/10090.ENSMUSP00000053877Constitutive coactivator of PPAR-gamma-like protein 1; Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabli [...]
Zfp457 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053879Zinc finger protein 457.
Itga2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053891Integrin alpha-2; Integrin alpha-2/beta-1 is a collagen receptor, being responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, [...]
Erbb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053897Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential comp [...]
Mafg protein networkhttps://string-db.org/network/10090.ENSMUSP00000053899Transcription factor MafG; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve [...]
Zmpste24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053900CAAX prenyl protease 1 homolog; Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C.
Sprn protein networkhttps://string-db.org/network/10090.ENSMUSP00000053901Shadow of prion protein; Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP.
Ston2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053908Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating (By similarity).
Lipk protein networkhttps://string-db.org/network/10090.ENSMUSP00000053913Lipase member K; Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers (By [...]
Dnajb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053916DnaJ homolog subfamily B member 4; Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro).
Chil3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053923Chitinase-like protein 3; Lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger than binding to mono- or [...]
Defb11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053932Beta-defensin 11; Has antibacterial activity.
Zfp583 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053935Zinc finger protein 583; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Krtap3-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053940Keratin-associated protein 3-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Basp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053943Brain acid soluble protein 1.
Usp42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053955Ubiquitin carboxyl-terminal hydrolase 42; Deubiquitinating enzyme which may play an important role during spermatogenesis; Belongs to the peptidase C19 family.
Lcn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053962Neutrophil gelatinase-associated lipocalin; Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2 [...]
Aasdhppt protein networkhttps://string-db.org/network/10090.ENSMUSP00000053971L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopante [...]
Drc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053972Dynein regulatory complex subunit 7; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the dist [...]
Inhbe protein networkhttps://string-db.org/network/10090.ENSMUSP00000053977Inhibin beta E chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diver [...]
Zfp959 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053979Zinc finger protein 959.
Lpar4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000053986Lysophosphatidic acid receptor 4; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stim [...]
Rprml protein networkhttps://string-db.org/network/10090.ENSMUSP00000053993Reprimo-like protein.
Zfp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054020Zinc finger protein 3; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Fbxo44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054022F-box only protein 44; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Gcc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054033GRIP and coiled-coil domain-containing protein 2; Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the [...]
Pfn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054053Profilin-3; Binds to actin and affects the structure of the cytoskeleton. Binds to poly-L-proline, phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5 [...]
Neurog3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054054Neurogenin-3; Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common [...]
Ankar protein networkhttps://string-db.org/network/10090.ENSMUSP00000054056Ankyrin and armadillo repeat-containing protein.
Galr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054062Galanin receptor type 2; Receptor for the hormone galanin, GALP and spexin-1. The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (v [...]
Spz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054083Spermatogenic leucine zipper protein 1; Transcription factor that binds to the DNA sequence 5'- CANNTG-3'(E box) and the G-box motif. Directly binds to a guanine-rich region of the PCNA promoter [...]
Heatr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054084HEAT repeat-containing 1.
Defb9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054085Beta-defensin 9; Has antibacterial activity.
Hcar2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054104Hydroxycarboxylic acid receptor 2; Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and de [...]
Hepacam protein networkhttps://string-db.org/network/10090.ENSMUSP00000054105Hepatocyte cell adhesion molecule; Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation (By similarity).
Pcdhb14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054111Protocadherin beta-14; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Tgs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054112Trimethylguanosine synthase; Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) [...]
Fbxo43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054125F-box only protein 43; Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyc [...]
Ikbke protein networkhttps://string-db.org/network/10090.ENSMUSP00000054126Inhibitor of nuclear factor kappa-B kinase subunit epsilon; Serine/threonine kinase that plays an essential role in regulating inflammatory responses to viral infection, through the activation of [...]
Ldlrad3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054134Low-density lipoprotein receptor class A domain-containing protein 3; May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide product [...]
Snx21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054137Sorting nexin-21; Binds to membranes enriched in phosphatidylinositol 3- phosphate (PtdIns(P3)) and phosphatidylinositol 4,5-bisphosphate. May be involved in several stages of intracellular traff [...]
Eva1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000054141Protein eva-1 homolog B.
Rapsn protein networkhttps://string-db.org/network/10090.ENSMUSP0000005415043 kDa receptor-associated protein of the synapse; Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the recept [...]
Pwwp2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000054154PWWP domain-containing protein 2A; H2A.Z-specific chromatin binding protein which may play an important role in the neural crest stem cell migration and differentiation during early development. [...]
Mycs protein networkhttps://string-db.org/network/10090.ENSMUSP00000054158Protein S-Myc; Has apoptosis-inducing activity.
Zfp207 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054168BUB3-interacting and GLEBS motif-containing protein ZNF207; Kinetochore- and microtubule-binding protein that plays a key role in spindle assembly. ZNF207/BuGZ is mainly composed of disordered lo [...]
Pnma3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054177Paraneoplastic antigen Ma3 homolog; Belongs to the PNMA family.
Hspb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054193Heat shock protein beta-3; Inhibitor of actin polymerization; Belongs to the small heat shock protein (HSP20) family.
Garem2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054208GRB2-associated and regulator of MAPK protein 2; Probable adapter protein that provides a critical link between cell surface epidermal growth factor receptor and the MAPK/ERK signaling pathway; B [...]
Pnoc protein networkhttps://string-db.org/network/10090.ENSMUSP00000054210Prepronociceptin; [Nociceptin]: Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in ne [...]
Cldn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054219Claudin-2; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
Mafa protein networkhttps://string-db.org/network/10090.ENSMUSP00000054226Transcription factor MafA; Transcriptional factor that activates insulin gene expression. Acts synergistically with NEUROD1/BETA2 and PDX1. Binds the insulin enhancer C1/RIPE3b element. Binds to [...]
P2rx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054233P2X purinoceptor 2; Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) [...]
Brd8dc protein networkhttps://string-db.org/network/10090.ENSMUSP00000054234BRD8 domain-containing.
1700020N01Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000054237RIKEN cDNA 1700020N01 gene.
Hjurp protein networkhttps://string-db.org/network/10090.ENSMUSP00000054263Holliday junction recognition protein; Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chape [...]
Ifnk protein networkhttps://string-db.org/network/10090.ENSMUSP00000054273Interferon kappa; May play a role in the regulation of immune cell function.
Lrp1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000054275Low-density lipoprotein receptor-related protein 1B; Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis; Belongs to the LDLR family.
Iqcf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054276IQ domain-containing protein F3.
Ccdc187 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054283Coiled-coil domain-containing protein 187.
Adam29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054292Disintegrin and metalloproteinase domain-containing protein 29; May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein (By similarity).
Cxxc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054307CXXC-type zinc finger protein 5; May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity i [...]
Stbd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054322Starch-binding domain-containing protein 1; Acts as a cargo receptor for glycogen. Delivers its cargo to an autophagic pathway called glycophagy, resulting in the transport of glycogen to lysosom [...]
Ankrd34b protein networkhttps://string-db.org/network/10090.ENSMUSP00000054330Ankyrin repeat domain-containing protein 34B; Belongs to the ANKRD34 family.
Plpp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054337Inactive phospholipid phosphatase 7; Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity. Knockdown in [...]
Map7d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054338MAP7 domain-containing protein 1; Belongs to the MAP7 family.
Gjb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054343Gap junction beta-2 protein; Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hex [...]
Olfr1352 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054355Olfactory receptor.
Kcnj10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054356ATP-sensitive inward rectifier potassium channel 10; May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a grea [...]
Ttc19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054367Tetratricopeptide repeat protein 19, mitochondrial; Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological [...]
Acad8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054370Isobutyryl-CoA dehydrogenase, mitochondrial; Isobutyryl-CoA dehydrogenase which catalyzes one of the steps of the valine catabolic pathway. To a lesser extent, is also able to catalyze the oxidat [...]
Pcdhb8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054371Protocadherin beta-8; Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination (Probable). Thereby, it is involved in the establishment and maintenan [...]
Ercc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054380General transcription and DNA repair factor IIH helicase subunit XPD; ATP-dependent 5'-3' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, whic [...]
Dpf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054385Zinc finger protein neuro-d4; May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the ne [...]
Ccn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054389CCN family member 3; Immediate-early protein playing a role in various cellular processes including proliferation, adhesion, migration, differentiation and survival. Acts by binding to integrins [...]
Slc5a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054407Sodium/glucose cotransporter 5; High capacity transporter for mannose and fructose and, to a lesser extent, glucose, AMG, and galactose; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) f [...]
Dnd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054412Dead end protein homolog 1; RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression (By similarity). Relieves miRNA repression in germline cell [...]
Fam120b protein networkhttps://string-db.org/network/10090.ENSMUSP00000054420Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation.
Eif3j2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054421Eukaryotic translation initiation factor 3 subunit J-B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of prote [...]
Rbm15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054424RNA-binding protein 15; RNA-binding protein that acts as a key regulator of N6- methyladenosine (m6A) methylation of RNAs, thereby regulating different processes, such as hematopoietic cell homeo [...]
F2rl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054426Proteinase-activated receptor 4; Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation; Belongs to t [...]
Mib1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054428E3 ubiquitin-protein ligase MIB1; E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notc [...]
Tex14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054444Inactive serine/threonine-protein kinase TEX14; Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular br [...]
Clec14a protein networkhttps://string-db.org/network/10090.ENSMUSP00000054451C-type lectin domain family 14 member A.
Mob1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000054452MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apop [...]
Nrl protein networkhttps://string-db.org/network/10090.ENSMUSP00000054457Neural retina-specific leucine zipper protein; Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B. Functions also as a trans [...]
Pqlc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054462Solute carrier family 66 member 3.
Insl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054488Insulin-like peptide INSL6 A chain; May have a role in sperm development and fertilization; Belongs to the insulin family.
Rps23 protein networkhttps://string-db.org/network/10090.ENSMUSP0000005449040S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RN [...]
Fn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054499Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wo [...]
Clca3a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054526Calcium-activated chloride channel regulator 3A-1; Plays a role in modulating chloride current across the plasma membrane in a calcium-dependent manner.
Fut8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054530Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
Rhbdl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054546Rhomboid-related protein 2, C-terminal fragment; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Known substrate [...]
Poldip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054548Polymerase delta-interacting protein 3; Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA trans [...]
Eef1a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054556Elongation factor 1-alpha 2; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation fac [...]
Fbln1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054583Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important fo [...]
Zfp13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054595Zinc finger protein 13; May be involved in transcriptional regulation.
Zkscan4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054604Zinc finger with KRAB and SCAN domains 4.
Tmem251 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054611Transmembrane protein 251.
Cdc42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054634Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In its active state binds to a variety [...]
Il27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054637Interleukin-27 subunit alpha; Associates with EBI3 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, tha [...]
A430005L14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000054638UPF0688 protein C1orf174 homolog.
Ifi27l2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000054698Interferon alpha-inducible protein 27-like protein 2A; May be involved in the interferon-induced negative regulation of the transcriptional activity of NR4A1, NR4A2 and NR4A3 through the enhancem [...]
Prr12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054702Proline-rich protein 12.
Fbxo28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054718F-box only protein 28; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
Npas2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054719Neuronal PAS domain-containing protein 2; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various ph [...]
Krtap7-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054720Keratin-associated protein 7-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Spryd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054731SPRY domain-containing protein 4.
Zc2hc1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000054734Zinc finger C2HC domain-containing protein 1A.
Plekhf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054745Pleckstrin homology domain-containing family F member 2; May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport (By similarity) [...]
Dpy19l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054747Probable C-mannosyltransferase DPY19L3; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins; Belongs to the dpy-19 family.
Amer3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054748APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell [...]
Olfr1414 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054752Olfactory receptor.
Ccdc169 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054771Coiled-coil domain-containing protein 169.
Pcdh20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054774Protocadherin-20; Potential calcium-dependent cell-adhesion protein.
Mc4r protein networkhttps://string-db.org/network/10090.ENSMUSP00000054776Melanocortin receptor 4; Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic [...]
Olfr873 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054778Olfactory receptor.
Pgbd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054788PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements.
Fancm protein networkhttps://string-db.org/network/10090.ENSMUSP00000054797Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination [...]
Dsg1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000054799Desmoglein-1-gamma; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Camta1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054804Calmodulin-binding transcription activator 1; Transcriptional activator; Belongs to the CAMTA family.
Helt protein networkhttps://string-db.org/network/10090.ENSMUSP00000054823Hairy and enhancer of split-related protein HELT; Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGCG-3'. Required for the development of GABAergic neur [...]
Henmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054829Small RNA 2'-O-methyltransferase; Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism [...]
Tmed2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054834Transmembrane emp24 domain-containing protein 2; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as car [...]
Gli2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054837Zinc finger protein GLI2; Functions as transcription regulator in the hedgehog (Hh) pathway. Functions as transcriptional activator. May also function as transcriptional repressor. Requires STK36 [...]
Ccdc69 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054840Coiled-coil domain-containing protein 69; May act as a scaffold to regulate the recruitment and assembly of spindle midzone components. Required for the localization of AURKB and PLK1 to the spin [...]
Xbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054852X-box-binding protein 1, cytoplasmic form; Functions as a transcription factor during endoplasmic reticulum stress by regulating the unfolded protein response (UPR). Required for cardiac myogenes [...]
Uqcr10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054856Cytochrome b-c1 complex subunit 9; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which dr [...]
Isca1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054858Iron-sulfur cluster assembly 1 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved [...]
Pcbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054863Poly(rC)-binding protein 1; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC.
Olfr866 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054864Olfactory receptor MOR145-5.
Higd1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000054881HIG1 domain family member 1A, mitochondrial; Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the [...]
Cd300e protein networkhttps://string-db.org/network/10090.ENSMUSP00000054883CMRF35-like molecule 2; Probably acts as an activating receptor.
B430306N03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000054890Triggering receptor expressed on myeloid cells-like 6.
Txndc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054909Thioredoxin domain-containing protein 2; Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulf [...]
Kcng3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054910Potassium voltage-gated channel subfamily G member 3; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulat [...]
Tnfrsf26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054938Tumor necrosis factor receptor superfamily member 26.
Cep68 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054943Centrosomal protein of 68 kDa; Involved in maintenance of centrosome cohesion, probably as part of a linker structure which prevents centrosome splitting. Required for localization of CDK5RAP2 to [...]
Itgb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054944Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands. ITGAV:ITGB6 acts as a recepto [...]
Cypt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054958Cysteine-rich perinuclear theca protein 4.
Lingo3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054960Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3.
Klhl11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054963Kelch-like protein 11; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their pr [...]
Exd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054980piRNA biogenesis protein EXD1; RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates [...]
Nhlrc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000054990E3 ubiquitin-protein ligase NHLRC1; E3 ubiquitin-protein ligase. Together with the phosphatase EPM2A/laforin, appears to be involved in the clearance of toxic polyglucosan and protein aggregates [...]
Msgn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055001Mesogenin-1; Involved in specifying the paraxial, but not dorsal, mesoderm. May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation.
Vcpkmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000055002Protein-lysine methyltransferase METTL21D; Protein-lysine N-methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity; Belongs to [...]
Usp48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055016Ubiquitin carboxyl-terminal hydrolase 48; Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of [...]
Krtap31-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055035Keratin-associated protein 31-2.
Lsm14b protein networkhttps://string-db.org/network/10090.ENSMUSP00000055036Protein LSM14 homolog B; May play a role in control of mRNA translation. Belongs to the LSM14 family.
Skor1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055037SKI family transcriptional corepressor 1; Inhibits BMP signaling (By similarity). Acts as a transcriptional corepressor of LBX1.
Nrsn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055048Neurensin-1; May play an important role in neural organelle transport, and in transduction of nerve signals or in nerve growth. May play a role in neurite extension.
Olfr938 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055053Olfactory receptor.
Trim34a protein networkhttps://string-db.org/network/10090.ENSMUSP00000055058Tripartite motif-containing protein 34A; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family.
Pcdhb17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055072Protocadherin beta 17.
Irak2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055073Interleukin-1 receptor-associated kinase-like 2; Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation [...]
Fam71b protein networkhttps://string-db.org/network/10090.ENSMUSP00000055079Protein FAM71B; May be involved in RNA biogenesis.
Kcnv2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055091Potassium voltage-gated channel subfamily V member 2; Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values (By s [...]
Sh3tc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055094SH3 domain and tetratricopeptide repeat-containing protein 2.
Ticam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055104TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF- kappa-B and interferon-regula [...]
Aqp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055110Aquaporin-3; Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC [...]
Epb41l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055122Band 4.1-like protein 2; Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase.
Evc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055130Limbin; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Plays a critical role in bone formation and skeletal development. May be involved in early embryoni [...]
Oxgr1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000551372-oxoglutarate receptor 1; Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway.
Vstm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055178V-set and transmembrane domain-containing protein 4; Peptide Lv enhances L-type voltage-gated calcium channel (L- VGCC) currents in retinal photoreceptors.
Pcdh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055199Protocadherin 1.
Tmem161b protein networkhttps://string-db.org/network/10090.ENSMUSP00000055208Transmembrane protein 161B.
Kcna1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055225Potassium voltage-gated channel subfamily A member 1; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the centra [...]
Ubqln3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055229Ubiquilin-3.
Olfr94 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055232Olfactory receptor 94.
Syt12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055237Synaptotagmin-12; Synaptic vesicle phosphoprotein that enhances spontaneous neurotransmitter release but does not effect induced neurotransmitter release (By similarity). Unlike other synaptotagm [...]
Gjd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055246Gap junction delta-3 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a [...]
Proser1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055253Proline and serine-rich protein 1.
Luc7l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055254Putative RNA-binding protein Luc7-like 2; May bind to RNA via its Arg/Ser-rich domain.
Krt9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055255Keratin, type I cytoskeletal 9; May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Play [...]
H2bfm protein networkhttps://string-db.org/network/10090.ENSMUSP00000055261H2B histone family, member M; Belongs to the histone H2B family.
Sowahb protein networkhttps://string-db.org/network/10090.ENSMUSP00000055267Ankyrin repeat domain-containing protein SOWAHB; Belongs to the SOWAH family.
Tmem178b protein networkhttps://string-db.org/network/10090.ENSMUSP00000055268Transmembrane protein 178B.
B230219D22Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000055271UPF0461 protein C5orf24 homolog; Belongs to the UPF0461 family.
Yars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055277Tyrosine--tRNA ligase, mitochondrial; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acc [...]
Foxc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055290Forkhead box protein C2; Transcriptional activator. Might be involved in the formation of special mesenchymal tissues.
Arhgef39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055293Rho guanine nucleotide exchange factor 39; Promotes cell proliferation.
Nhlrc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055295NHL repeat-containing protein 3.
P4ha3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055297Prolyl 4-hydroxylase subunit alpha-3; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family.
Tmem239 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055299Transmembrane protein 239.
Kif13a protein networkhttps://string-db.org/network/10090.ENSMUSP00000055304Kinesin-like protein KIF13A; Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) [...]
Foxo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055308Forkhead box protein O1; Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response eleme [...]
Yod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055318Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. M [...]
Bbs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055321Bardet-Biedl syndrome 1 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is [...]
Kctd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055326BTB/POZ domain-containing protein KCTD8; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter [...]
Kcnrg protein networkhttps://string-db.org/network/10090.ENSMUSP00000055327Potassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes (By similarity).
Il17rc protein networkhttps://string-db.org/network/10090.ENSMUSP00000055343Interleukin-17 receptor C; Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA. Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeri [...]
Myo3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000055362Myosin-IIIb; Probable actin-based motor with a protein kinase activity (By similarity). Required for normal cochlear hair bundle development and hearing. Plays an important role in the early step [...]
Ripply2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055369Protein ripply2; Plays a role in somitogenesis. Required for somite segregation and establishment of rostrocaudal polarity in somites. Belongs to the ripply family.
Vmn1r179 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055372Vomeronasal type-1 receptor.
Zfp768 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055374Zinc finger protein 768; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Saysd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055382SAYSvFN domain-containing protein 1.
Spag11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000055391Sperm associated antigen 11A.
Hamp protein networkhttps://string-db.org/network/10090.ENSMUSP00000055404Hepcidin; Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, [...]
1700019D03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000055413Small membrane A-kinase anchor protein; Binds to type I regulatory subunits of protein kinase A (PKA- RI) and may anchor/target them to the plasma membrane.
Kcne4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055415Potassium voltage-gated channel subfamily E member 4; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates t [...]
Diras2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055416GTP-binding protein Di-Ras2; Displays low GTPase activity and exists predominantly in the GTP-bound form; Belongs to the small GTPase superfamily. Di-Ras family.
Cdc25c protein networkhttps://string-db.org/network/10090.ENSMUSP00000055427M-phase inducer phosphatase 3; Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. Directly dephosphorylates CDK1 [...]
Neurl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055437E3 ubiquitin-protein ligase NEURL3; E3 ubiquitin-protein ligase. Seems to utilize UBE2E1. In vitro, generates polyubiquitin chains via non-canonical lysine residues suggesting that it is not invo [...]
Rp1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055449Retinitis pigmentosa 1-like 1 protein; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors.
Olfr891 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055451Olfactory receptor 891.
3300002I08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000055454RIKEN cDNA 3300002I08 gene.
Cpox protein networkhttps://string-db.org/network/10090.ENSMUSP00000055455Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of copropo [...]
Taok1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055470Serine/threonine-protein kinase TAO1; Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoske [...]
Unc119b protein networkhttps://string-db.org/network/10090.ENSMUSP00000055475Protein unc-119 homolog B; Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for t [...]
Dnajc22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055482DnaJ homolog subfamily C member 22; May function as a co-chaperone.
Pced1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000055485PC-esterase domain-containing protein 1B; Belongs to the PC-esterase family.
Osr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055486Protein odd-skipped-related 1; Transcription factor that plays a role in the regulation of embryonic heart and urogenital development.
Bhlha15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055493Class A basic helix-loop-helix protein 15; Plays a role in controlling the transcriptional activity of MyoD, ensuring that expanding myoblast populations remain undifferentiated. Repression may o [...]
Krtap19-5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055511Keratin-associated protein 19-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Zfp286 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055517Zinc finger protein 286.
Vmn1r76 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055518Vomeronasal type-1 receptor.
Mlkl protein networkhttps://string-db.org/network/10090.ENSMUSP00000055521Mixed lineage kinase domain-like protein; Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to [...]
Tmem88 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055528Transmembrane protein 88; Inhibits the Wnt/beta-catenin signaling pathway. Crucial for heart development and acts downstream of GATA factors in the pre- cardiac mesoderm to specify lineage commit [...]
Ddx17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055535Probable ATP-dependent RNA helicase DDX17; As an RNA helicase, unwinds RNA and alters RNA structures through ATP binding and hydrolysis. Involved in multiple cellular processes, including pre-mRN [...]
Krtap13-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055537Keratin-associated protein 13-1.
Trim16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055542Tripartite motif-containing protein 16; E3 ubiquitin ligase that plays an essential role in the organization of autophagic response and ubiquitination upon lysosomal and phagosomal damages. Plays [...]
Gpr61 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055557G-protein coupled receptor 61; Orphan G-protein coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway (By similarity). Shows a reciprocal regulatory interaction with th [...]
Nccrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055562F-box only protein 50; Promotes cell proliferation.
Ffar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055564Free fatty acid receptor 1; G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding incr [...]
Zfp106 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055602Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Requir [...]
Diras1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055605GTP-binding protein Di-Ras1; Displays low GTPase activity and exists predominantly in the GTP-bound form; Belongs to the small GTPase superfamily. Di-Ras family.
Mrps16 protein networkhttps://string-db.org/network/10090.ENSMUSP0000005561928S ribosomal protein S16, mitochondrial; Belongs to the bacterial ribosomal protein bS16 family.
Marcksl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055637MARCKS-related protein; Involved in the control of cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migra [...]
Tmem232 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055652Transmembrane protein 232.
6030458C11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000055656UPF0489 protein C5orf22 homolog.
Ttll10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055671Protein polyglycylase TTLL10; Polyglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of [...]
Kcna5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055673Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective [...]
Pdss1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055689Decaprenyl-diphosphate synthase subunit 1; Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10. Belongs to the FPP/GGPP synthase family.
Fbxo46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055692F-box only protein 46; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Cavin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055694Caveolae-associated protein 2; Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae (By similarity). Plays a [...]
P2ry6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055697P2Y purinoceptor 6; Receptor for extracellular UTP > ADP = 2-methylthio-ATP > ADP-beta-S > ATP = ATP-gamma-S. The activity of this receptor is mediated by G proteins which activate a phosphatidyl [...]
Tst protein networkhttps://string-db.org/network/10090.ENSMUSP00000055743Thiosulfate sulfurtransferase; Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA (By [...]
Qrfp protein networkhttps://string-db.org/network/10090.ENSMUSP00000055746Orexigenic neuropeptide QRFP; Stimulates feeding and grooming behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone s [...]
Nod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055747Nucleotide-binding oligomerization domain-containing protein 1; Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular [...]
Ranbp3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000055750Ran-binding protein 3-like; Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocki [...]
Pcsk9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055757Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein rece [...]
Rfesd protein networkhttps://string-db.org/network/10090.ENSMUSP00000055763Rieske domain-containing protein.
Secisbp2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000055772Selenocysteine insertion sequence-binding protein 2-like; Binds SECIS (Sec insertion sequence) elements present on selenocysteine (Sec) protein mRNAs, but does not promote Sec incorporation into [...]
Klre1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055779Killer cell lectin-like receptor subfamily E member 1; Lectin-like receptor for natural killer (NK) cells. Can either inhibit or activate NK cell cytotoxic activity, depending on its binding part [...]
Cnr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055797Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycer [...]
Gm5065 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055799Galectin-related protein B; Does not bind lactose, and may not bind carbohydrates.
Glb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055803Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family.
Haspin protein networkhttps://string-db.org/network/10090.ENSMUSP00000055806Serine/threonine-protein kinase haspin; Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate act [...]
Prtg protein networkhttps://string-db.org/network/10090.ENSMUSP00000055815Protogenin; May play a role in anteroposterior axis elongation.
Pstpip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055823Proline-serine-threonine phosphatase-interacting protein 1; Involved in regulation of the actin cytoskeleton. May regulate WAS actin-bundling activity. Bridges the interaction between ABL1 and PT [...]
Fahd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055827Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro (By similarity). Also has oxaloacetate decarboxylase [...]
Arf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055862ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesi [...]
P2ry4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055869P2Y purinoceptor 4; Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system.
Olfr1367 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055870Olfactory receptor.
Syne4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055874Nesprin-4; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic intera [...]
Gm10681 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055886NADPH-dependent 3-keto-steroid reductase Hsd3b4; Responsible for the reduction of the oxo group on the C-3 of 5alpha-androstane steroids. Catalyzes the conversion of dihydrotestosterone to its in [...]
Tmem64 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055892Transmembrane protein 64; Positively regulates TNFSF11-induced osteoclast differentiation. Acts as a regulator of TNFSF11-mediated Ca(2+) signaling pathways via its interaction with SERCA2 which [...]
Abraxas1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055895BRCA1-A complex subunit Abraxas 1; Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the [...]
Gm9789 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055898Predicted gene 9789.
Cracr2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000055899EF-hand calcium-binding domain-containing protein 4A; Plays a role in store-operated Ca(2+) entry (SOCE).
Stx19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055901Syntaxin-19; Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR).
Smcr8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055926Guanine nucleotide exchange protein SMCR8; Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, C9 [...]
Hs3st3a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055930Heparan sulfate glucosamine 3-O-sulfotransferase 3A1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosam [...]
Olfr474 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055931Olfactory receptor 474; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Mosmo protein networkhttps://string-db.org/network/10090.ENSMUSP00000055934Modulator of smoothened protein; Acts as a negative regulator of hedgehog signaling probably by promoting internalization and subsequent degradation of smoothened protein (SMO) present in the cil [...]
A530064D06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000055935Triggering receptor expressed in myeloid cells 4.
Zfp518a protein networkhttps://string-db.org/network/10090.ENSMUSP00000055956Zinc finger protein 518A; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Gpr156 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055958Probable G-protein coupled receptor 156; Orphan receptor; Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
Parn protein networkhttps://string-db.org/network/10090.ENSMUSP00000055969Poly(A)-specific ribonuclease PARN; 3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tai [...]
Ptx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055984Pentraxin-4.
Tmem121 protein networkhttps://string-db.org/network/10090.ENSMUSP00000055994Transmembrane protein 121; May play a role in MAPK signaling.
Irgm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056001Immunity-related GTPase family M member 2.
Il17c protein networkhttps://string-db.org/network/10090.ENSMUSP00000056008Interleukin-17C; Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibac [...]
Tent5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000056015Terminal nucleotidyltransferase 5B; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase.
Thtpa protein networkhttps://string-db.org/network/10090.ENSMUSP00000056026Thiamine-triphosphatase; Hydrolase highly specific for thiamine triphosphate (ThTP). Belongs to the ThTPase family.
Sigmar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056027Sigma non-opioid intracellular receptor 1; Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the bio [...]
Yipf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056039Protein YIPF6; May be required for stable YIPF1 and YIPF2 protein expression.
Dscam protein networkhttps://string-db.org/network/10090.ENSMUSP00000056040Down syndrome cell adhesion molecule homolog; Cell adhesion molecule that plays a role in neuronal self- avoidance. Promotes repulsion between specific neuronal processes of either the same cell [...]
Alkbh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056043DNA oxidative demethylase ALKBH2; Dioxygenase that repairs alkylated DNA and RNA containing 1- methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA contain [...]
Duxbl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056056Double homeodomain protein.
Zfp420 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056077Zinc finger protein.
Gldn protein networkhttps://string-db.org/network/10090.ENSMUSP00000056080Gliomedin shedded ectodomain; Ligand for NRCAM and NFASC/neurofascin that plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Mediates interaction between S [...]
Gm11437 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056084Uncharacterized protein C17orf78 homolog.
Abhd17b protein networkhttps://string-db.org/network/10090.ENSMUSP00000056099Alpha/beta hydrolase domain-containing protein 17B; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards DLG4/PSD95. Has depalmitoylating ac [...]
Zfp668 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056105Zinc finger protein 668; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Wwc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056121Protein WWC2; Belongs to the WWC family.
Acot6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056131Acyl-coenzyme A thioesterase 6; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to r [...]
Ckap2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000056145Cytoskeleton-associated protein 2-like; Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells.
Hivep1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056147Zinc finger protein 40; Transcription factor which binds specifically to the palindromic sequence 5'-GGGAAATCCC-3' in the alpha-A crystallin promoter.
Pcdhb11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056148Protocadherin beta 11.
Otc protein networkhttps://string-db.org/network/10090.ENSMUSP00000056152Ornithine carbamoyltransferase, mitochondrial.
Zfp830 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056154Zinc finger protein 830; May play a role in pre-mRNA splicing as component of the spliceosome (By similarity). Acts as an important regulator of the cell cycle that participates in the maintenanc [...]
Cox8c protein networkhttps://string-db.org/network/10090.ENSMUSP00000056155Cytochrome c oxidase subunit 8C, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The re [...]
Ufsp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056156Ufm1-specific protease 1; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Do [...]
Krtap4-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056162Keratin-associated protein 4-2.
Slc17a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056182Sialin; Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Medi [...]
C1ql3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056188Complement C1q-like protein 3; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Plays a role in glucose homeostasis. Vi [...]
Suox protein networkhttps://string-db.org/network/10090.ENSMUSP00000056195Sulfite oxidase, mitochondrial.
D630023F18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000056196Uncharacterized protein C2orf80 homolog.
Klhdc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056212Kelch domain-containing protein 9.
Nudt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056219Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation. Belongs to the Nudix hydrolase family.
A530016L24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000056220Nutritionally-regulated adipose and cardiac-enriched protein.
Jmjd1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000056227Probable JmjC domain-containing histone demethylation protein 2C; Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code [...]
Clrn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056245Clarin-3.
Krtap19-4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056250Keratin-associated protein 19-4; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Map3k19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056254Mitogen-activated protein kinase kinase kinase 19; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
4933402E13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000056260RIKEN cDNA 4933402E13 gene.
Aldh3b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056276Aldehyde dehydrogenase family 3 member B1; Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde (By similarity). Low activity towards acetaldehyde and [...]
Dpagt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056282UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pat [...]
Sprr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056287Small proline-rich protein 3; Cross-linked envelope protein of keratinocytes; Belongs to the cornifin (SPRR) family.
Ear14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056293Non-secretory ribonuclease; This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Possesses a wide variety of bi [...]
Nyx protein networkhttps://string-db.org/network/10090.ENSMUSP00000056313Nyctalopin; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily.
Hoxb13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056315Homeobox protein Hox-B13; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posteri [...]
Zfp280b protein networkhttps://string-db.org/network/10090.ENSMUSP00000056340Zinc finger protein 280B.
Pcdhb16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056347Protocadherin beta 16.
Tmtc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056353Protein O-mannosyl-transferase TMTC1; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl- transferases dedicated pr [...]
Fbxw21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056358F-box and WD-40 domain protein 21.
Lhfp protein networkhttps://string-db.org/network/10090.ENSMUSP00000056364LHFPL tetraspan subfamily member 6 protein.
Ubqlnl protein networkhttps://string-db.org/network/10090.ENSMUSP00000056365Ubiquilin-like protein.
Pnlip protein networkhttps://string-db.org/network/10090.ENSMUSP00000056377Pancreatic triacylglycerol lipase; Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycer [...]
Ttc12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056378Tetratricopeptide repeat protein 12.
Atat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056383Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynami [...]
Sall2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056401Sal-like protein 2; Probable transcription factor that plays a role in eye development before, during, and after optic fissure closure. Belongs to the sal C2H2-type zinc-finger protein family.
Bod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056417Biorientation of chromosomes in cell division protein 1; Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles. Belongs to t [...]
Rnase2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000056418Ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin); Belongs to the pancreatic ribonuclease family.
Pcdhb10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056420Protocadherin beta 10.
Pcdhb21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056424Protocadherin beta 21.
Npsr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056432Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pa [...]
Rap2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000056433Ras-related protein Rap-2a; Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors incl [...]
Olfr324 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056457Olfactory receptor.
Arhgap15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056461Rho GTPase-activating protein 15; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in a [...]
Rnf112 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056464RING finger protein 112; E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic d [...]
Ftdc protein networkhttps://string-db.org/network/10090.ENSMUSP00000056475Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
9530053A07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000056479RIKEN cDNA 9530053A07 gene.
Mettl21e protein networkhttps://string-db.org/network/10090.ENSMUSP00000056481Protein-lysine methyltransferase METTL21E; Protein-lysine methyltransferase.
Prss27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056483Serine protease 27.
Tcf25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056485Transcription factor 25; May play a role in cell death control. Acts as a transcriptional repressor. Has been shown to repress transcription of SRF in vitro and so may play a role in heart develo [...]
Idh3g protein networkhttps://string-db.org/network/10090.ENSMUSP00000056502Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial; Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) [...]
Zfp41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056510Zinc finger protein 41; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis; Belongs to the krueppel C2H2-type zinc-finger protein family.
Ccdc171 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056520Coiled-coil domain-containing protein 171.
Krt81 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056525Keratin, type II cuticular Hb1.
Btbd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056529BTB/POZ domain-containing protein 8.
Phlpp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056530PH domain leucine-rich repeat-containing protein phosphatase 1; Protein phosphatase involved in regulation of Akt and PKC signaling. Mediates dephosphorylation in the C-terminal domain hydrophobi [...]
Kcng4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056552Potassium voltage-gated channel subfamily G member 4; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulat [...]
Fam43a protein networkhttps://string-db.org/network/10090.ENSMUSP00000056555Protein FAM43A; Belongs to the FAM43 family.
Npy4r protein networkhttps://string-db.org/network/10090.ENSMUSP00000056576Neuropeptide Y receptor type 4; Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP >> PYY >= NPY.
Tas2r126 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056581Taste receptor type 2 member 41; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal [...]
Tssc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056582Protein TSSC4.
Psg23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056586Pregnancy-specific glycoprotein 23.
Dnajb8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056592DnaJ homolog subfamily B member 8; Efficient suppressor of aggregation and toxicity of disease- associated polyglutamine proteins.
H2bc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056604Histone H2B type 1-A; Variant histone specifically required to direct the transformation of dissociating nucleosomes to protamine in male germ cells. Entirely replaces classical histone H2B prior [...]
Zfp689 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056610Zinc finger protein 689; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Lcp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056621Lymphocyte cytosolic protein 2; Involved in T-cell antigen receptor mediated signaling.
Krt34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056622Keratin, type I cuticular Ha4; Belongs to the intermediate filament family.
Clec9a protein networkhttps://string-db.org/network/10090.ENSMUSP00000056625C-type lectin domain family 9 member A; Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes fil [...]
Lrit2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056642Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2.
Pgrmc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056643Membrane-associated progesterone receptor component 2; Receptor for steroids.
Gpank1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056646G patch domain and ankyrin repeat-containing protein 1.
Sun1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056655SUN domain-containing protein 1; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nuc [...]
Prokr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056659Prokineticin receptor 2; Receptor for prokineticin 2. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinosit [...]
Plac9a protein networkhttps://string-db.org/network/10090.ENSMUSP00000056665Placenta-specific protein 9; Belongs to the PLAC9 family.
Cd14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056669Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby me [...]
Catsperz protein networkhttps://string-db.org/network/10090.ENSMUSP00000056681Cation channel sperm-associated protein subunit zeta; Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm [...]
Pp2d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056682Protein phosphatase 2C-like domain-containing protein 1; Belongs to the PP2C family.
C87499 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056691Expressed sequence C87499.
Lamtor4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056693Ragulator complex protein LAMTOR4, N-terminally processed; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growt [...]
Ly6e protein networkhttps://string-db.org/network/10090.ENSMUSP00000056703Lymphocyte antigen 6E; Involved in T-cell development. Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs ma [...]
Galnt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056705Polypeptide N-acetylgalactosaminyltransferase 6; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threon [...]
Atxn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056715Ataxin-2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. Belongs to the ataxin-2 family.
Gtf3c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056719General transcription factor 3C polypeptide 1; Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required fo [...]
Ifnb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056720Interferon beta; Has antiviral, antibacterial and anticancer activities; Belongs to the alpha/beta interferon family.
Rarres1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056728Retinoic acid receptor responder (tazarotene-induced) 1.
Gpr107 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056739Protein GPR107; Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor (By similarity). Involved in blood sugar regulation through the ind [...]
Sfmbt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056744Scm-like with four MBT domains protein 1; Histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by c [...]
Fgf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056752Fibroblast growth factor 4; Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Is essential for survival of the postimplantation mou [...]
Kif1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000056754Kinesin-like protein KIF1B; Motor for anterograde transport of mitochondria. Has a microtubule plus end-directed motility.
Ubtd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056765Ubiquitin domain-containing protein 2.
Pik3r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056774Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p [...]
E2f8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056778Transcription factor E2F8; Atypical E2F transcription factor that participates in various processes such as angiogenesis and polyploidization of specialized cells. Mainly acts as a transcription [...]
1110032F04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000056782Uncharacterized membrane protein C3orf80 homolog.
Nup62 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056785Nuclear pore glycoprotein p62; Essential component of the nuclear pore complex. The N- terminal is probably involved in nucleocytoplasmic transport. The C- terminal is involved in protein-protein [...]
Ankrd34c protein networkhttps://string-db.org/network/10090.ENSMUSP00000056787Ankyrin repeat domain-containing protein 34C; Belongs to the ANKRD34 family.
Tmem259 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056792Membralin; May have a role in the ERAD pathway required for clearance of misfolded proteins in the endoplasmic reticulum (ER). Promotes survival of motor neurons, probably by protecting against E [...]
Tmem104 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056805Transmembrane protein 104.
H2-Eb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056814Histocompatibility 2, class II antigen E beta2.
Gimap5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056820GTPase IMAP family member 5; Plays a role in T lymphocyte development and the optimal generation of CD4/CD8 double-positive thymocytes. Inhibitor of GSK3A. May act by sequestering GSK3A in cytopl [...]
Ankrd37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056828Ankyrin repeat domain-containing protein 37.
Cfd protein networkhttps://string-db.org/network/10090.ENSMUSP00000056836Complement factor D; Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its funct [...]
Olfr735 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056851Olfactory receptor.
Mrps9 protein networkhttps://string-db.org/network/10090.ENSMUSP0000005685528S ribosomal protein S9, mitochondrial; Belongs to the universal ribosomal protein uS9 family.
Cfap70 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056869Cilia and flagella-associated protein 70.
Tent5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000056872Terminal nucleotidyltransferase 5C; Nucleotidyltransferase that act as a non-canonical poly(A) RNA polymerase which enhances mRNA stability and gene expression. Mainly targets mRNAs encoding endo [...]
Fcer1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000056882High affinity immunoglobulin epsilon receptor subunit alpha; Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding o [...]
Ubqln2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056888Ubiquilin-2; Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin- proteasome system (UPS), autophagy and the endoplasmic reticul [...]
Zbtb11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056923Zinc finger and BTB domain-containing protein 11; May be involved in transcriptional regulation.
Klk14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056935Kallikrein-14; Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and [...]
Nrn1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000056940Neuritin-like protein; Belongs to the neuritin family.
Ier5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056948Immediate early response gene 5 protein; Plays a role as a transcription factor. Mediates positive transcriptional regulation of several chaperone gene during the heat shock response in a HSF1-de [...]
Vwce protein networkhttps://string-db.org/network/10090.ENSMUSP00000056958Von Willebrand factor C and EGF domain-containing protein; May be a regulatory element in the beta-catenin signaling pathway and a target for chemoprevention of hapatocellular carcinoma.
Zfp771 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056959Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Sall3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056967Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family.
Ajuba protein networkhttps://string-db.org/network/10090.ENSMUSP00000056977LIM domain-containing protein ajuba; Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate d [...]
Zfp697 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056979Zinc finger protein 697; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Ric3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000056990Protein RIC-3; Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotonin [...]
Oas1f protein networkhttps://string-db.org/network/10090.ENSMUSP000000569932'-5' oligoadenylate synthetase 1F.
Lrrn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057005Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory.
Fam187b protein networkhttps://string-db.org/network/10090.ENSMUSP00000057020Protein FAM187B; Belongs to the FAM187 family.
Ppp1r15b protein networkhttps://string-db.org/network/10090.ENSMUSP00000057062Protein phosphatase 1 regulatory subunit 15B; Maintains low levels of EIF2S1 phosphorylation in unstressed cells by promoting its dephosphorylation by PP1. Belongs to the PPP1R15 family.
Pram1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057065PML-RARA-regulated adapter molecule 1; May be involved in integrin signaling in neutrophils. Binds to PtdIns(4)P.
Spata2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057095Spermatogenesis-associated protein 2; Bridging factor that mediates the recruitment of CYLD to the LUBAC complex, thereby regulating TNF-alpha-induced necroptosis (By similarity). Acts as a direc [...]
Dsg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057096Desmoglein-2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Frmd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057103FERM domain-containing protein 7; Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability.
Olig3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057106Oligodendrocyte transcription factor 3; May determine the distinct specification program of class A neurons in the dorsal part of the spinal cord and suppress specification of class B neurons.
Ctxn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057115Cortexin-1; May mediate extracellular or intracellular signaling of cortical neurons during forebrain development; Belongs to the cortexin family.
Tmem150c protein networkhttps://string-db.org/network/10090.ENSMUSP00000057116Transmembrane protein 150C; Component of a mechanosensitive cation channel. Confers mechanically activated (MA) currents with slow inactivation kinetics. May contribute to proprioception. Belongs [...]
Gimap7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057143GTPase, IMAP family member 7.
Mageh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057157Melanoma-associated antigen H1.
Zfp418 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057159Zinc finger protein 418.
Olfr918 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057210Olfactory receptor.
Htr5b protein networkhttps://string-db.org/network/10090.ENSMUSP000000572125-hydroxytryptamine receptor 5B; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mit [...]
Tigd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057223Tigger transposable element-derived protein 2.
Prop1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057231Homeobox protein prophet of Pit-1; Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.
Lsm8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057238U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatal [...]
Zfp397 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057253Zinc finger protein 397.
Bri3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057263Brain protein I3; Participates in tumor necrosis factor-alpha (TNF)-induced cell death. May be a target of Wnt/beta-catenin signaling in the liver (By similarity).
Champ1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057270Chromosome alignment-maintaining phosphoprotein 1; Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle [...]
Rspry1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057275RING finger and SPRY domain-containing protein 1.
Otud7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000057282OTU domain-containing protein 7A; Has deubiquitinating activity towards 'Lys-11'-linked polyubiquitin chains.
Olfr522 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057288Olfactory receptor.
H1f4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057308Histone H1.4; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucle [...]
Wdr72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057320WD repeat-containing protein 72; Plays a major role in formation of tooth enamel. Specifically required during the maturation phase of amelogenesis for normal formation of the enamel matrix and c [...]
Gpr6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057323G-protein coupled receptor 6; Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity [...]
Naa11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057336N-alpha-acetyltransferase 11; Displays alpha (N-terminal) acetyltransferase activity. Proposed alternative catalytic subunit of the N-terminal acetyltransferase A (NatA) complex.
Hexim1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057339Protein HEXIM1; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP com [...]
Neto1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057340Neuropilin and tolloid-like protein 1; Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for m [...]
Dusp18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057346Dual specificity protein phosphatase 18; Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphoth [...]
Sc5d protein networkhttps://string-db.org/network/10090.ENSMUSP00000057354Lathosterol oxidase; Catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterol.
Slc36a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057355Proton-coupled amino acid transporter 4; Functions as a sodium-independent electroneutral transporter for tryptophan, proline and alanine; Belongs to the amino acid/polyamine transporter 2 family [...]
Msantd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057362Myb/SANT-like DNA-binding domain-containing protein 1.
Npm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057365Nucleoplasmin-2; Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during [...]
Camk2n2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057368Calcium/calmodulin-dependent protein kinase II inhibitor 2; Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2 (By similarity). Belongs to the CAMK2 [...]
Golph3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057375Golgi phosphoprotein 3; Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from [...]
Pudp protein networkhttps://string-db.org/network/10090.ENSMUSP00000057378Pseudouridine-5'-phosphatase; Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine.
Cetn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057392Centrin-1; Plays a fundamental role in microtubule-organizing center structure and function (By similarity). Plays a role in sperm cilia formation ; Belongs to the centrin family.
Fam221b protein networkhttps://string-db.org/network/10090.ENSMUSP00000057398Protein FAM221B.
Loxl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057406Lysyl oxidase homolog 1; Active on elastin and collagen substrates.
Ceacam19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057433Carcinoembryonic antigen-related cell adhesion molecule 19.
Krtap9-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057445Keratin-associated protein 9-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Trhde protein networkhttps://string-db.org/network/10090.ENSMUSP00000057449Thyrotropin-releasing hormone-degrading ectoenzyme; Specific inactivation of TRH after its release.
C87436 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057461Uncharacterized protein C2orf42 homolog.
Vti1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000057462Vesicle transport through interaction with t-SNAREs homolog 1B; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are [...]
Zbtb22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057466Zinc finger and BTB domain-containing protein 22; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Wdr47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057482WD repeat-containing protein 47.
Dmrta1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057488Doublesex- and mab-3-related transcription factor A1; Belongs to the DMRT family.
Nhlh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057489Helix-loop-helix protein 1; May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.
Sema5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000057494Semaphorin-5B; May act as positive axonal guidance cues.
Zfp786 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057495Zinc finger protein 786; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Pigz protein networkhttps://string-db.org/network/10090.ENSMUSP00000057509GPI mannosyltransferase 4; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers a fourth mannose to some trimannosyl- GPIs during GPI precursor assembly. T [...]
Zbtb12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057515Zinc finger and BTB domain-containing 12.
Pcdhb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057519Protocadherin beta 1.
B3galt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057521Beta-1,3-galactosyltransferase 6; Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Has a preference for gala [...]
Tle4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057527Transducin-like enhancer protein 4; Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF fa [...]
Hrk protein networkhttps://string-db.org/network/10090.ENSMUSP00000057532Activator of apoptosis harakiri; Promotes apoptosis.
Gnai2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057543Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The [...]
Wdfy4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057556WD repeat- and FYVE domain-containing protein 4; Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts [...]
Hdgfl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057557Hepatoma derived growth factor-like 1.
Gp1ba protein networkhttps://string-db.org/network/10090.ENSMUSP00000057563Platelet glycoprotein Ib alpha chain; GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to [...]
Fbxo31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057573F-box only protein 31; Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin- [...]
Hcrt protein networkhttps://string-db.org/network/10090.ENSMUSP00000057578Orexin-A; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these com [...]
Tmem174 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057581Transmembrane protein 174.
Trp53i13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057592Tumor protein p53-inducible protein 13; May act as a tumor suppressor. Inhibits tumor cell growth, when overexpressed (By similarity).
Slc27a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057595Very long-chain acyl-CoA synthetase; Acyl CoA synthetase that activates long-chain and very long- chain fatty acids (VLCFAs) by catalyzing the formation of fatty acyl- CoA. Can also activate bran [...]
Rbpms2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057600RNA-binding protein with multiple splicing 2; RNA-binding protein involved in the regulation of smooth muscle cell differentiation and proliferation in the gastrointestinal system (By similarity) [...]
Otol1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057607Otolin-1; Collagen-like protein specifically expressed in the inner ear, which provides an organic scaffold for otoconia, a calcium carbonate structure in the saccule and utricle of the ear. Acts [...]
Lix1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000057623LIX1-like protein; Belongs to the LIX1 family.
Ppip5k1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057632Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphos [...]
Zscan22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057651Zinc finger and SCAN domain-containing 22.
Rab2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000057664Ras-related protein Rab-2A; Required for protein transport from the endoplasmic reticulum to the Golgi complex.
Rhot1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057669Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (B [...]
Fam174a protein networkhttps://string-db.org/network/10090.ENSMUSP00000057670Membrane protein FAM174A.
Dusp28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057690Dual specificity phosphatase 28; Has phosphatase activity with the synthetic substrate 6,8- difluoro-4-methylumbelliferyl phosphate (in vitro). Has almost no detectable activity with phosphotyros [...]
Vtcn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057721V-set domain containing T-cell activation inhibitor 1; Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of [...]
Cpa5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057722Carboxypeptidase A5.
Rtn4rl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057725Reticulon-4 receptor-like 2; Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity). Plays a functionally redundant [...]
Nelfb protein networkhttps://string-db.org/network/10090.ENSMUSP00000057731Negative elongation factor B; Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (Pol II). The NELF complex, which a [...]
Rdh9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057732Cis-retinol/androgen dehydrogenase type 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Tspan31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057751Tetraspanin-31.
Lce1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000057762Late cornified envelope 1L.
Rangap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057771Ran GTPase-activating protein 1; GTPase activator for RAN. Converts cytoplasmic GTP-bound RAN to GDP-bound RAN, which is essential for RAN-mediated nuclear import and export. Mediates dissociatio [...]
Spink14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057781Serine peptidase inhibitor, Kazal type 14.
Adam20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057794A disintegrin and metallopeptidase domain 20.
Adamts12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057796A disintegrin and metalloproteinase with thrombospondin motifs 12; Metalloprotease that plays a role in the degradation of COMP (By similarity). Cleaves also alpha-2 macroglobulin and aggregan. H [...]
Samd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057805Sterile alpha motif domain-containing protein 3.
Zfp36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057815mRNA decay activator protein ZFP36; Zinc-finger RNA-binding protein that destabilizes numerous cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail remova [...]
Tyw3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057828tRNA wybutosine-synthesizing protein 3 homolog; Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper [...]
Olfr1153 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057839Olfactory receptor.
Blnk protein networkhttps://string-db.org/network/10090.ENSMUSP00000057844B-cell linker protein; Functions as a central linker protein, downstream of the B- cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outc [...]
Spsb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057849SPRY domain-containing SOCS box protein 4; Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitina [...]
Zbtb7c protein networkhttps://string-db.org/network/10090.ENSMUSP00000057856Zinc finger and BTB domain-containing protein 7C; May be a tumor suppressor gene.
Phospho1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057858Phosphoethanolamine/phosphocholine phosphatase; Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). Involved in the generation of inorganic phosphate [...]
Dgkq protein networkhttps://string-db.org/network/10090.ENSMUSP00000057859Diacylglycerol kinase theta; Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). May regulate the activity of protein kinase C by controlling the balance between these two sig [...]
Tmem198 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057865Transmembrane protein 198; Promotes LRP6 phosphorylation by casein kinases and thereby plays a role in Wnt signaling. May be a membrane scaffold protein involved in the self-aggregation of LRP6 t [...]
Slc25a44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057871Solute carrier family 25 member 44; Mitochondrial solute transporter which transports branched- chain amino acid (BCAA; valine, leucine and isoleucine) into mitochondria in brown adipose tissue ( [...]
Ccdc71 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057891Coiled-coil domain-containing protein 71.
Otulin protein networkhttps://string-db.org/network/10090.ENSMUSP00000057893Ubiquitin thioesterase otulin; Deubiquitinase that specifically removes linear ('Met-1'- linked) polyubiquitin chains to substrates and acts as a regulator of angiogenesis and innate immune respo [...]
Kif9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057896Kinesin-like protein KIF9.
Fbxo48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057901F-box only protein 48.
Mgat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057905Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; Plays an essential role in protein N-glycosylation. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) onto the free te [...]
Tas2r143 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057910Taste receptor type 2 member 143; Putative taste receptor which may play a role in the perception of bitterness.
Ntf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057916Neurotrophin-4; Could serve as a target-derived trophic factor for sensory and sympathetic neurons; Belongs to the NGF-beta family.
Pcdhb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057921Protocadherin beta 2.
Trim10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057928Tripartite motif-containing protein 10; Seems to play an important role in erythropoiesis; Belongs to the TRIM/RBCC family.
Cenpe protein networkhttps://string-db.org/network/10090.ENSMUSP00000057938Centromere-associated protein E; Microtubule plus-end-directed kinetochore motor which plays an important role in chromosome congression, microtubule-kinetochore conjugation and spindle assembly [...]
Gskip protein networkhttps://string-db.org/network/10090.ENSMUSP00000057939GSK3B-interacting protein; A-kinase anchoring protein for GSK3B and PKA that regulates or facilitates their kinase activity towards their targets. The ternary complex enhances Wnt-induced signali [...]
Tmem72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057942Transmembrane protein 72.
Trpc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057965Short transient receptor potential channel 6; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger s [...]
Cd24a protein networkhttps://string-db.org/network/10090.ENSMUSP00000057983Signal transducer CD24; May have a pivotal role in cell differentiation of different cell types. May have a specific role in early thymocyte development. Signaling could be triggered by the bindi [...]
Riox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057984Ribosomal oxygenase 1; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. [...]
Bdnf protein networkhttps://string-db.org/network/10090.ENSMUSP00000057989Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected ne [...]
Saxo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000057993Stabilizer of axonemal microtubules 2; Belongs to the FAM154 family.
Fem1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000057996Protein fem-1 homolog A-A; Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via [...]
A4galt protein networkhttps://string-db.org/network/10090.ENSMUSP00000057999Lactosylceramide 4-alpha-galactosyltransferase; Catalyzes the transfer of galactose from UDP-alpha-D- galactose to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl- (1<->1)-ceramide(d18: [...]
Mrgpre protein networkhttps://string-db.org/network/10090.ENSMUSP00000058000Mas-related G-protein coupled receptor member E; Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain; Belongs to the G-protein coup [...]
Spata33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058002Spermatogenesis-associated protein 33.
Tas2r105 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058006Taste receptor type 2 member 105; Gustducin-coupled cycloheximide receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB [...]
Crb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058007Protein crumbs homolog 2; Apical polarity protein that plays a central role during the epithelial-to-mesenchymal transition (EMT) at gastrulation, when newly specified mesodermal cells move insid [...]
Vsig8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058008V-set and immunoglobulin domain-containing protein 8.
Onecut1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058020Hepatocyte nuclear factor 6; Transcriptional activator. Binds the consensus sequence 5'- DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes [...]
Timeless protein networkhttps://string-db.org/network/10090.ENSMUSP00000058021Protein timeless homolog; Plays an important role in the control of DNA replication, maintenance of replication fork stability, maintenance of genome stability throughout normal DNA replication, [...]
Slc25a26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058028S-adenosylmethionine mitochondrial carrier protein; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Specifically mediates t [...]
Zfpm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058037Zinc finger protein ZFPM1; Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodim [...]
Sstr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058040Somatostatin receptor type 3; Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
Rab11fip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058042Rab11 family-interacting protein 1; A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and phagoc [...]
Il31ra protein networkhttps://string-db.org/network/10090.ENSMUSP00000058045Interleukin-31 receptor subunit alpha; Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediate [...]
F830045P16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000058047RIKEN cDNA F830045P16 gene.
Lingo4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058050Leucine-rich repeat and immunoglobulin-like domain containing-NOGO receptor-interacting protein 4.
Ccdc126 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058077Coiled-coil domain-containing protein 126.
Kif2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000058084Kinesin-like protein KIF2B; Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement during mitosis. Has microtubule depolymerization activity. Plays a [...]
Olfr829 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058101Olfactory receptor.
Trim56 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058109E3 ubiquitin-protein ligase TRIM56; E3 ubiquitin-protein ligase that plays a key role in innate antiviral immunity. In response to pathogen- and host-derived double- stranded DNA (dsDNA), targets [...]
Vwde protein networkhttps://string-db.org/network/10090.ENSMUSP00000058110Von Willebrand factor D and EGF domain-containing protein.
Ccnjl protein networkhttps://string-db.org/network/10090.ENSMUSP00000058111Cyclin-J-like protein; Belongs to the cyclin family. Cyclin J subfamily.
E130311K13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000058114Protein C3orf33 homolog; May play a role in transcription regulation.
Sprr2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000058131Small proline-rich protein 2B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane [...]
Ephb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058135Ephrin type-B receptor 2; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling [...]
Gm597 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058140Predicted gene 597.
Vwc2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000058142Von Willebrand factor C domain-containing protein 2-like; May play a role in neurogenesis. May promote matrix mineralization , but has been shown to weakly, but significantly inhibit BMP2 and BMP [...]
Fam89a protein networkhttps://string-db.org/network/10090.ENSMUSP00000058156Protein FAM89A.
Zbtb8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000058157Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.
Dcaf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058168DDB1- and CUL4-associated factor 7; Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The acti [...]
Fbxw15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058175F-box/WD repeat-containing protein 15; Substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes KAT7 ubiquitination and subsequent degradatio [...]
Erich5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058182Glutamate-rich protein 5.
Gpr101 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058183Probable G-protein coupled receptor 101; Orphan receptor.
Clrn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058204Clrn2 protein.
Hmx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058205Homeobox protein HMX2; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development.
Lemd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058221LEM domain-containing protein 2; Involved in nuclear structure organization. Required for maintaining the integrity of the nuclear envelope (By similarity).
Hcrtr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058230Orexin receptor type 2; Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding.
Fbxo10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058233F-box only protein 10; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. The SCF(FBXO10) complex mediates ubiquitination and degradation of BC [...]
S100a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058237Protein S100-A1; Probably acts as a Ca(2+) signal transducer. In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers a conformational change. This conformational [...]
Rnf125 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058251E3 ubiquitin-protein ligase RNF125; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, such as DDX58/RIG-I, MAVS/IPS1, IFIH1/MDA5, [...]
B4galnt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058253Beta-1,4-N-acetylgalactosaminyltransferase 3; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediam [...]
Nxph3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058254Neurexophilin-3; May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins; Belongs to the neurexophilin family.
Adam26a protein networkhttps://string-db.org/network/10090.ENSMUSP00000058256Disintegrin and metalloproteinase domain-containing protein 26A; Sperm surface membrane protein that may be involved in spermatogenesis and fertilization.
Myt1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000058264Myelin transcription factor 1-like protein; Transcription factor that plays a key role in neuronal differentiation by specifically repressing expression of non-neuronal genes during neuron differ [...]
Coa6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058279Cytochrome c oxidase assembly factor 6 homolog; Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV a [...]
Timm29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058283Mitochondrial import inner membrane translocase subunit Tim29; Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitoc [...]
C2cd4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000058286C2 calcium-dependent domain-containing 4A.
Zfp119b protein networkhttps://string-db.org/network/10090.ENSMUSP00000058300Zinc finger protein 119b.
Slc4a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058313Sodium bicarbonate cotransporter 3; Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Regulates intracellular pH and may play a role in bicarb [...]
Tmem221 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058317Transmembrane protein 221.
Cavin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058321Caveolae-associated protein 1; Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues. Core component of the CAVIN complex which is [...]
Fam185a protein networkhttps://string-db.org/network/10090.ENSMUSP00000058333Protein FAM185A.
Gal3st1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058348Galactosylceramide sulfotransferase; Catalyzes the sulfation of membrane glycolipids. Seems to prefer beta-glycosides at the non-reducing termini of sugar chains attached to a lipid moiety. Catal [...]
Msx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058354Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis; Belongs to the Msh home [...]
Polr1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000058355DNA-directed RNA polymerases I and III subunit RPAC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common co [...]
Cts3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058359Cts3 protein; Belongs to the peptidase C1 family.
Pcdhga11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058362Protocadherin gamma subfamily A, 11.
B3galnt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058363UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1; Transfers N-acetylgalactosamine onto globotriaosylceramide. Plays a critical role in preimplantation stage embryonic development ; Belongs [...]
Rpl18a protein networkhttps://string-db.org/network/10090.ENSMUSP0000005836860S ribosomal protein L18a.
Tdrp protein networkhttps://string-db.org/network/10090.ENSMUSP00000058371Testis development-related protein; Contributes to normal sperm motility, but not essential for male fertility; Belongs to the TDRP family.
Upf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058375Regulator of nonsense transcripts 2; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by [...]
Rap2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000058391Ras-related protein Rap-2c; Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell sprea [...]
Lmbr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058405Limb region 1 protein; Putative membrane receptor.
Tmem82 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058412Transmembrane protein 82.
Rps21 protein networkhttps://string-db.org/network/10090.ENSMUSP0000005843240S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family.
Teddm1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000058437Transmembrane epididymal protein 1B.
St7l protein networkhttps://string-db.org/network/10090.ENSMUSP00000058455Suppressor of tumorigenicity 7 protein-like.
Zfp536 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058468Zinc finger protein 536; May be involved in transcriptional regulation. Recognizes and binds 2 copies of the core DNA sequence 5'-CCCCCA-3' (By similarity). Belongs to the krueppel C2H2-type zinc [...]
BC048671 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058483Uncharacterized protein C3orf22 homolog.
Ccdc125 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058484Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration.
Hoxd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058490Homeobox protein Hox-D9; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Ubiad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058502UbiA prenyltransferase domain-containing protein 1; Prenyltransferase that mediates the formation of menaquinone- 4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform required for endothelial [...]
Atf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058521Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA dam [...]
Spesp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058522Sperm equatorial segment protein 1; Involved in fertilization ability of sperm.
Serpina9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058535Serpin A9.
Cryga protein networkhttps://string-db.org/network/10090.ENSMUSP00000058548Gamma-crystallin A; Crystallins are the dominant structural components of the vertebrate eye lens.
Ces2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000058567Acylcarnitine hydrolase; Hydrolase with high activity towards palmitoylcarnitine. Is also active with p-nitrophenylacetate and alpha-naphthylacetate. Belongs to the type-B carboxylesterase/lipase [...]
Ptprq protein networkhttps://string-db.org/network/10090.ENSMUSP00000058572Phosphatidylinositol phosphatase PTPRQ; Phosphatidylinositol phosphatase required for auditory function. May act by regulating the level of phosphatidylinositol 4,5- bisphosphate (PIP2) level in [...]
Foxd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058575Forkhead box protein D4.
Zfp146 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058588Zinc finger protein OZF; Belongs to the krueppel C2H2-type zinc-finger protein family.
Pcdhb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058592Protocadherin beta-6; Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination. Thereby, it is involved in the establishment and maintenance of speci [...]
Mlf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058596Myeloid leukemia factor 1; Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-ind [...]
Tmem199 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058599Transmembrane protein 199; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intrace [...]
Zfp507 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058609Zinc finger protein 507; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Naip5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058611Baculoviral IAP repeat-containing protein 1e; Sensor component of the NLRC4 inflammasome that specifically recognizes and binds flagellin from pathogenic bacteria such as Legionella or Salmonella [...]
Sorl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058613Sortilin-related receptor; Sorting receptor that directs several proteins to their correct location within the cell. Along with AP-1 complex, involved Golgi apparatus - endosome sorting. Sorting [...]
Sprr1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000058617Cornifin-B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transg [...]
Bod1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000058618Biorientation of chromosomes in cell division protein 1-like 1; Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2- dependent [...]
Fzd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058629Frizzled-1; Receptor for Wnt proteins. Activated by WNT7B. Activated by WNT3A, WNT3, WNT1 and to a lesser extent WNT2, but apparently not by WNT4, WNT5A, WNT5B, WNT6, WNT7A or WNT7B (By similarit [...]
Rnf24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058630RING finger protein 24; May play a role in TRPCs intracellular trafficking.
Tcim protein networkhttps://string-db.org/network/10090.ENSMUSP00000058631Transcriptional and immune response regulator; Seems to be involved in the regulation of cell growth an differentiation, may play different and opposite roles depending on the tissue or cell type [...]
Lce1h protein networkhttps://string-db.org/network/10090.ENSMUSP00000058647Late cornified envelope 1H.
Foxi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058651Forkhead box protein I1; Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH [...]
Pramef8 protein networkhttps://string-db.org/network/10090.ENSMUSP000000586764732496O08Rik protein.
Slc35f6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058680Solute carrier family 35 member F6; Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PD [...]
H2-M10.4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058686Histocompatibility 2, M region locus 10.4; Belongs to the MHC class I family.
Mc2r protein networkhttps://string-db.org/network/10090.ENSMUSP00000058691Adrenocorticotropic hormone receptor; Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP).
Med26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058697Mediator of RNA polymerase II transcription subunit 26; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Slc6a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058699Sodium- and chloride-dependent glycine transporter 2; Sodium- and chloride-dependent glycine transporter. Terminates the action of glycine by its high affinity sodium-dependent reuptake into pres [...]
Mypop protein networkhttps://string-db.org/network/10090.ENSMUSP00000058718Myb-related transcription factor, partner of profilin; Transcriptional repressor; DNA-binding protein that specifically recognizes the core sequence 5'-YAAC[GT]G-3'. Dimerization with PFN1 reduce [...]
4921504E06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000058720RIKEN cDNA 4921504E06 gene.
Tmed3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058723Transmembrane emp24 domain-containing protein 3; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED1 [...]
Rxfp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058732Relaxin-3 receptor 2; High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation (By similarit [...]
Rabl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058746Rab-like protein 6; May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A (By similarity); Belongs to the small GTPase superfamily. Rab family.
Hoxa6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058755Homeobox protein Hox-A6; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Ptpn11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058757Tyrosine-protein phosphatase non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to [...]
Olfml2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000058761Olfactomedin-like protein 2A.
Gpr135 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058762G-protein coupled receptor 135; Orphan receptor. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR [...]
Fads6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058783Fatty acid desaturase 6.
Rrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058785Ribosomal RNA processing protein 1 homolog A; Plays a critical role in the generation of 28S rRNA.
Olfr1123 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058786Olfactory receptor.
Pcdhb9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058801Protocadherin beta 9.
Olfr77 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058810Olfactory receptor.
Gm9833 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058811Myelin expression factor 2.
Spice1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058832Spindle and centriole-associated protein 1; Regulator required for centriole duplication, for proper bipolar spindle formation and chromosome congression in mitosis.
Skint10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058838Selection and upkeep of intraepithelial T-cells protein 10; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus; Belongs to the SKINT family.
Atp7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000058840Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular co [...]
Aph1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000058846Gamma-secretase subunit APH-1A; Non-catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch [...]
Adam34l protein networkhttps://string-db.org/network/10090.ENSMUSP00000058858A disintegrin and metallopeptidase domain 34-like.
Prss54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058859Inactive serine protease 54.
AU021092 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058860UPF0764 protein C16orf89 homolog.
Siglech protein networkhttps://string-db.org/network/10090.ENSMUSP00000058875Sialic acid-binding Ig-like lectin H.
Slc25a41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058877Solute carrier family 25 member 41; Belongs to the mitochondrial carrier (TC 2.A.29) family.
Hepacam2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058882HEPACAM family member 2; Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosome [...]
Gpr151 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058887G-protein coupled receptor 151 protein; Proton-sensing G-protein coupled receptor.
Ubald2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058894UBA-like domain-containing protein 2; Belongs to the UBALD family.
Ddit4l protein networkhttps://string-db.org/network/10090.ENSMUSP00000058896DNA damage-inducible transcript 4-like protein; Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Belongs to the DDIT4 family.
Cdca4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058901Cell division cycle-associated protein 4; May participate in the regulation of cell proliferation through the E2F/RB pathway (By similarity). May be involved in molecular regulation of hematopoie [...]
Rpl37a protein networkhttps://string-db.org/network/10090.ENSMUSP0000005891960S ribosomal protein L37a; Belongs to the eukaryotic ribosomal protein eL43 family.
Olfr95 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058929Olfactory receptor.
Olfr1445 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058933Olfactory receptor.
Edem3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058941ER degradation-enhancing alpha-mannosidase-like protein 3; Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose [...]
Ddx28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058950Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this [...]
Angptl8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058951Angiopoietin-like protein 8; Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: requi [...]
Trmt10c protein networkhttps://string-db.org/network/10090.ENSMUSP00000058954tRNA methyltransferase 10 homolog C; Mitochondrial tRNA N(1)-methyltransferase involved in mitochondrial tRNA maturation. Component of mitochondrial ribonuclease P, a complex composed of TRMT10C/ [...]
Epb41l5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058966Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells.
Dcun1d3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058968DCN1-like protein 3; Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane.
Fam166b protein networkhttps://string-db.org/network/10090.ENSMUSP00000058980Protein FAM166B.
Cog7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000058990Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function.
Ferd3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000058994Fer3-like protein; Transcription factor that binds to the E-box and functions as inhibitor of transcription. DNA binding requires dimerization with an E protein. Inhibits transcription activation [...]
Rimkla protein networkhttps://string-db.org/network/10090.ENSMUSP00000058996N-acetylaspartylglutamate synthase A; Catalyzes the synthesis of N-acetyl-L-aspartyl-L-glutamate (NAAG) and N-acetyl-L-aspartyl-L-glutamyl-L-glutamate.
Itgbl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059019Integrin beta-like protein 1.
Six1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059026Homeobox protein SIX1; Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several or [...]
Hip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059033Huntingtin-interacting protein 1; Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependen [...]
Myorg protein networkhttps://string-db.org/network/10090.ENSMUSP00000059038Myogenesis-regulating glycosidase; Putative glycosidase. Promotes myogenesis by activating AKT signaling through the maturation and secretion of IGF2.
Ssbp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059039Single stranded DNA-binding protein 4.
Smtnl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059043Smoothelin-like protein 2; Belongs to the smoothelin family.
Spo11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059056Meiotic recombination protein SPO11; [Isoform 1]: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms th [...]
BC048562 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059069cDNA sequence BC048562.
Ube2dnl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059077Ubiquitin-conjugating enzyme E2D N-terminal-like 2; Belongs to the ubiquitin-conjugating enzyme family.
Chd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059079Chromodomain-helicase-DNA-binding protein 7; Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production (By similarity); Belongs to the SNF2/RAD54 helicase family.
Fkrp protein networkhttps://string-db.org/network/10090.ENSMUSP00000059091Fukutin-related protein; Catalyzes the transfer of CDP-ribitol to ribitol 5-phosphate previously attached by FKTN/fukutin of to the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- [...]
1810030O07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000059095Uncharacterized protein CXorf38 homolog.
Gm5414 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059101Type II keratin Kb14; Belongs to the intermediate filament family.
Crebrf protein networkhttps://string-db.org/network/10090.ENSMUSP00000059102CREB3 regulatory factor; Acts as a negative regulator of the endoplasmic reticulum stress response or unfolded protein response (UPR). Represses the transcriptional activity of CREB3 during the U [...]
Slc2a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059106Solute carrier family 2, facilitated glucose transporter member 7; Probable sugar transporter. Its physiological substrate is subject to discussion. Does not transport galactose, 2-deoxy-d-glucos [...]
Socs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059129Suppressor of cytokine signaling 3; SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of [...]
Vkorc1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059139Vitamin K epoxide reductase complex subunit 1-like protein 1; Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K (in vitro), and may contribute to vit [...]
Borcs6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059143BLOC-1-related complex subunit 6; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BO [...]
Mplkip protein networkhttps://string-db.org/network/10090.ENSMUSP00000059154M-phase-specific PLK1-interacting protein; May play a role in maintenance of cell cycle integrity by regulating mitosis or cytokinesis.
Aspm protein networkhttps://string-db.org/network/10090.ENSMUSP00000059159Abnormal spindle-like microcephaly-associated protein homolog; Involved in mitotic spindle regulation and coordination of mitotic processes. The function in regulating microtubule dynamics at spi [...]
Edrf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059166Erythroid differentiation-related factor 1; Transcription factor involved in erythroid differentiation. Involved in transcriptional activation of the globin gene (By similarity).
Ctbs protein networkhttps://string-db.org/network/10090.ENSMUSP00000059167Di-N-acetylchitobiase; Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N- acetylglucosamine chitobiose core from the reducing end of [...]
Lacc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059173Laccase domain-containing protein 1; Central regulator of the metabolic function and bioenergetic state of macrophages. In macrophages, promotes flux through de novo lipogenesis to concomitantly [...]
Pcdhb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059180Protocadherin beta 3.
Mcm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059192DNA replication licensing factor MCM3; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiat [...]
Ifne protein networkhttps://string-db.org/network/10090.ENSMUSP00000059199Interferon epsilon; Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Di [...]
Maml1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059210Mastermind-like protein 1; Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnov [...]
Ercc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059211DNA excision repair protein ERCC-8; Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide e [...]
Mab21l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059212Protein mab-21-like 3; Belongs to the mab-21 family.
C1galt1c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059224C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycop [...]
Pcmtd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059261Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.
Gp1bb protein networkhttps://string-db.org/network/10090.ENSMUSP00000059270Platelet glycoprotein Ib beta chain; Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to [...]
Nup160 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059289Nuclear pore complex protein Nup160; Functions as a component of the nuclear pore complex (NPC). Involved in poly(A)+ RNA transport.
Depdc1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000059291DEP domain-containing protein 1B.
Tefm protein networkhttps://string-db.org/network/10090.ENSMUSP00000059304Transcription elongation factor, mitochondrial; Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, inc [...]
Olfr1022 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059312Olfactory receptor 1022.
Nat8l protein networkhttps://string-db.org/network/10090.ENSMUSP00000059313N-acetylaspartate synthetase; Plays a role in the regulation of lipogenesis by producing N- acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and [...]
Adam6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000059315A disintegrin and metallopeptidase domain 6A.
Tmco4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059320Transmembrane and coiled-coil domain-containing protein 4; Belongs to the TMCO4 family.
Rbm15b protein networkhttps://string-db.org/network/10090.ENSMUSP00000059330Putative RNA-binding protein 15B; RNA-binding protein that acts as a key regulator of N6- methyladenosine (m6A) methylation of RNAs, thereby regulating different processes, such as alternative sp [...]
Lcn10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059353Epididymal-specific lipocalin-10; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis.
Gimap6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059371GTPase IMAP family member 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
Cbfb protein networkhttps://string-db.org/network/10090.ENSMUSP00000059382Core-binding factor subunit beta; Forms the heterodimeric complex core-binding factor (CBF) with RUNX family proteins (RUNX1, RUNX2, and RUNX3). RUNX members modulate the transcription of their t [...]
Nipbl protein networkhttps://string-db.org/network/10090.ENSMUSP00000059385Nipped-B-like protein; Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodimeric complex (also known as cohesin loading complex) with MAU2/SCC4 which mediates [...]
Arhgap30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059389Rho GTPase-activating protein 30; GTPase-activating protein (GAP) for RAC1 and RHOA, but not for CDC42.
Shisa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059391Protein shisa-2 homolog; Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. Belongs to the shisa family.
Eif2s3x protein networkhttps://string-db.org/network/10090.ENSMUSP00000059395Eukaryotic translation initiation factor 2 subunit 3, X-linked; As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eI [...]
Pura protein networkhttps://string-db.org/network/10090.ENSMUSP00000059404Transcriptional activator protein Pur-alpha; This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the c-Myc gene [...]
Sfxn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059419Sideroflexin-3; Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway. Mitochondrial serine is converted to [...]
Foxo4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059420Forkhead box protein O4; Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down [...]
A2ml1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059426Ovostatin homolog; Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism.
C2cd4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000059433C2 calcium-dependent domain-containing protein 4C; Belongs to the C2CD4 family.
Trap1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000059448Tumor rejection antigen P815A.
Spty2d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059457Protein SPT2 homolog; Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin. Required for normal chromatin refolding [...]
Krtap5-4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059461Keratin-associated protein 5-4; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated protein (KRTAP), which a [...]
Lrrc3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000059463Leucine-rich repeat-containing protein 3B.
Mbtps2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059471Membrane-bound transcription factor site-2 protease; Involved in regulated intramembrane proteolysis (RIP) that is the cleavage of membrane-spanning regulatory proteins by proteases within the pl [...]
Prss33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059491Serine protease 33; Serine protease that has amidolytic activity, cleaving its substrates before Arg residues.
Tmem11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059494Transmembrane protein 11, mitochondrial; Plays a role in mitochondrial morphogenesis.
Rhoj protein networkhttps://string-db.org/network/10090.ENSMUSP00000059498Rho-related GTP-binding protein RhoJ; Plasma membrane-associated small GTPase specifically involved in angiogenesis (By similarity). Required for endothelial cell migration during vascular develo [...]
Spin2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000059499Spindlin-2C; May be involved in the regulation of cell cycle progression. Exhibits H3K4me3-binding activity.
Vamp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059501Vesicle-associated membrane protein 8; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on [...]
Mtus1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059503Microtubule-associated tumor suppressor 1 homolog; Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, [...]
Cactin protein networkhttps://string-db.org/network/10090.ENSMUSP00000059533Cactin; Involved in the regulation of innate immune response (By similarity). Acts as negative regulator of Toll-like receptor, interferon-regulatory factor (IRF) and canonical NF-kappa-B signali [...]
Dok7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059538Protein Dok-7; Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor ( [...]
4921511C20Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000059542RIKEN cDNA 4921511C20 gene.
Cyp4x1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059545Cytochrome P450 4X1; A cytochrome P450 monooxygenase that selectively catalyzes the epoxidation of the last double bond of the arachidonoyl moiety of anandamide, potentially modulating endocannab [...]
Zfp943 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059554Zinc finger prtoein 943.
Lrrc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059570Leucine-rich repeat-containing protein 3.
Clec4g protein networkhttps://string-db.org/network/10090.ENSMUSP00000059574C-type lectin domain family 4 member G; Binds mannose, N-acetylglucosamine (GlcNAc) and fucose, but not galactose, in a Ca(2+)-dependent manner.
Defb19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059585Beta-defensin 19; Has antibacterial activity; Belongs to the beta-defensin family.
Gja3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059587Gap junction alpha-3 protein; Structural component of lens fiber gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the dockin [...]
Pcdhb15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059598Protocadherin beta 15.
Hmgb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059625High mobility group protein B4.
Prm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059630Protamine-3; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.
Ccdc96 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059636Coiled-coil domain-containing protein 96.
Nlrc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059637NLR family CARD domain-containing protein 4; Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome [...]
Klhl31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059643Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response elem [...]
Dmrt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059654Doublesex- and mab-3-related transcription factor 2; Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific m [...]
She protein networkhttps://string-db.org/network/10090.ENSMUSP00000059658SH2 domain-containing adapter protein E.
Defb36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059665Beta-defensin 36; Has antibacterial activity; Belongs to the beta-defensin family.
Pde12 protein networkhttps://string-db.org/network/10090.ENSMUSP000000596662',5'-phosphodiesterase 12; Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modula [...]
Prss50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059668Probable threonine protease PRSS50; May be involved in proteolysis through its threonine endopeptidase activity; Belongs to the peptidase S1 family.
Ap1ar protein networkhttps://string-db.org/network/10090.ENSMUSP00000059669Adaptor-related protein complex 1-associated regulatory protein.
Zfp622 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059678Zinc finger protein 622; May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development.
Zfp456 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059686Zinc finger protein 456.
Adra2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000059705Alpha-2C adrenergic receptor; Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins; Belongs to the G-protein coupled re [...]
Ppp1r17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059708Protein phosphatase 1 regulatory subunit 17; Inhibits phosphatase activities of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) complexes.
Cyb5d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059709Cytochrome b5 domain-containing protein 1.
Znrf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059715E3 ubiquitin-protein ligase ZNRF4; E3 ubiquitin-protein ligase which specifically induces ubiquitination and proteasomal degradation of CANX within the endoplasmic reticulum (By similarity). Coul [...]
Samhd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059717Deoxynucleoside triphosphate triphosphohydrolase SAMHD1; [Isoform 1]: Protein that acts both as a host restriction factor involved in defense response to virus and as a regulator of DNA end resec [...]
Nsun3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059720tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial; Mitochondrial tRNA methyltransferase that mediates methylation of cytosine to 5-methylcytosine (m5C) at position 34 of mt- tRNA(Met). mt [...]
Olfr722 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059721Olfactory receptor.
Tceanc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059741Transcription elongation factor A N-terminal and central domain-containing protein 2.
Rbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059749Retinol-binding protein 1; Cytoplasmic retinol-binding protein. Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage and retinoid homeostasis.
Polq protein networkhttps://string-db.org/network/10090.ENSMUSP00000059757DNA polymerase theta; DNA polymerase that promotes microhomology-mediated end- joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand br [...]
Defb15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059763Beta-defensin 15; Has antibacterial activity.
Pcdhb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059770Protocadherin beta 4.
Pqlc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059772Lysosomal amino acid transporter 1 homolog; Amino acid transporter that specifically mediates the pH- dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes.
Ivl protein networkhttps://string-db.org/network/10090.ENSMUSP00000059780Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
Isg20l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059783Interferon-stimulated 20 kDa exonuclease-like 2; 3'-> 5'-exoribonuclease involved in ribosome biogenesis in the processing of the 12S pre-rRNA. Displays a strong specificity for a 3'-end containi [...]
Bricd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059792BRICHOS domain containing 5.
Ube2q2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059798Ubiquitin-conjugating enzyme E2 Q2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination; Belongs [...]
Pfkm protein networkhttps://string-db.org/network/10090.ENSMUSP00000059801ATP-dependent 6-phosphofructokinase, muscle type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
Oog3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059834Oogenesin-3; Belongs to the PRAME family.
Ccdc17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059848Coiled-coil domain-containing protein 17.
Scd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059860Acyl-CoA desaturase 4; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes th [...]
Otud6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000059861OTU domain-containing protein 6A; Deubiquitinating enzyme that hydrolyzes 'Lys-27'-, 'Lys- 29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains ( [...]
Lgsn protein networkhttps://string-db.org/network/10090.ENSMUSP00000059871Lengsin; May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens. Does not seem to have e [...]
Cdc42ep2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059883Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pse [...]
Olfr1443 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059886Olfactory receptor.
Acpp protein networkhttps://string-db.org/network/10090.ENSMUSP00000059889Prostatic acid phosphatase; A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphat [...]
Mtmr9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059894Myotubularin-related protein 9; Acts as an adapter for myotubularin-related phosphatases. Increases lipid phosphatase MTMR6 catalytic activity, specifically towards phosphatidylinositol 3,5-bisph [...]
Slc29a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059896Equilibrative nucleoside transporter 4; Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenyl [...]
Ankrd45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059923Ankyrin repeat domain-containing protein 45.
Stambpl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059927AMSH-like protease; Zinc metalloprotease that specifically cleaves 'Lys-63'- linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity).
Ulk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059947Serine/threonine-protein kinase ULK3; Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in th [...]
Creb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059973Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence prese [...]
Ptgs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059977Prostaglandin G/H synthase 1; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in t [...]
Rab11fip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000059978Rab11 family-interacting protein 2; A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the tran [...]
Nudt1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000599837,8-dihydro-8-oxoguanine triphosphatase; Antimutagenic. Plays a redundant role in sanitizing oxidized nucleotide pools, such as 8-oxo-dGTP pools. Acts as a sanitizing enzyme for oxidized nucleoti [...]
Bex1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060005Protein BEX1; Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to n [...]
Tmem74b protein networkhttps://string-db.org/network/10090.ENSMUSP00000060017Transmembrane protein 74B.
Selenon protein networkhttps://string-db.org/network/10090.ENSMUSP00000060026Selenoprotein N; Plays an important role in cell protection against oxidative stress and in the regulation of redox-related calcium homeostasis. Regulates the calcium level of the ER by protectin [...]
Guca1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000060027Guanylyl cyclase-activating protein 1; Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevat [...]
Crlf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060028Cytokine receptor-like factor 3; May play a role in the negative regulation of cell cycle progression.
Zfp366 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060040Zinc finger protein 366; Has transcriptional repression activity. Acts as corepressor of ESR1; the function seems to involve CTBP1 and histone deacetylases.
Chd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060054Chromodomain-helicase-DNA-binding protein 4; Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.
Jak3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060073Tyrosine-protein kinase JAK3; Non-receptor tyrosine kinase involved in various processes such as cell growth, development, or differentiation. Mediates essential signaling events in both innate a [...]
Tacstd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060099Tumor-associated calcium signal transducer 2; May function as a growth factor receptor.
Trim12c protein networkhttps://string-db.org/network/10090.ENSMUSP00000060100Tripartite motif-containing 12C.
Trim26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060103Tripartite motif-containing protein 26; E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors [...]
Kcnj9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060110G protein-activated inward rectifier potassium channel 3; This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium [...]
Ppp1r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060118Protein phosphatase inhibitor 2; Inhibitor of protein-phosphatase 1.
Spsb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060124SPRY domain-containing SOCS box protein 2; Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitina [...]
Themis protein networkhttps://string-db.org/network/10090.ENSMUSP00000060129Protein THEMIS; Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lin [...]
Fbxl22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060137F-box and leucine-rich protein 22; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes ubiquitination of sarcomeric proteins alpha-acti [...]
Grrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060143Protein FAM110D; Belongs to the FAM110 family.
Gpa33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060147Cell surface A33 antigen; May play a role in cell-cell recognition and signaling.
Tmie protein networkhttps://string-db.org/network/10090.ENSMUSP00000060148Transmembrane inner ear expressed protein; Unknown. The protein may play some role in a cellular membrane location. May reside within an internal membrane compartment and function in pathways suc [...]
Mylk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060149Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Rtl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060157Retrotransposon Gag-like protein 3; May function as a transcriptional regulator (Probable). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal [...]
Ubr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060159E3 ubiquitin-protein ligase UBR3; E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N-terminal residues that are destabilizing [...]
Igfals protein networkhttps://string-db.org/network/10090.ENSMUSP00000060169Insulin-like growth factor-binding protein complex acid labile subunit; May have an important role in regulating the access of circulating IGFs to the tissues.
Fam131a protein networkhttps://string-db.org/network/10090.ENSMUSP00000060194Protein FAM131A; Belongs to the FAM131 family.
4932438A13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000060199Transmembrane protein KIAA1109.
Uck2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060202Uridine-cytidine kinase 2; Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use [...]
Efcab9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060205EF-hand calcium-binding domain-containing protein 9; pH-dependent Ca(2+) sensor required to activate the CatSper channel, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivat [...]
Idnk protein networkhttps://string-db.org/network/10090.ENSMUSP00000060218Probable gluconokinase; Belongs to the gluconokinase GntK/GntV family.
Snx33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060225Sorting nexin-33; Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during i [...]
Hs3st5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060229Heparan sulfate glucosamine 3-O-sulfotransferase 5; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine res [...]
Ppp1r37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060233Protein phosphatase 1 regulatory subunit 37; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Belongs to the PPP1R37 family.
Tmem86b protein networkhttps://string-db.org/network/10090.ENSMUSP00000060237Lysoplasmalogenase; Enzyme catalyzing the degradation of lysoplasmalogen. Lysoplasmalogens are formed by the hydrolysis of the abundant membrane glycerophospholipids plasmalogens. May control the [...]
Tubb2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000060246Tubulin beta-2A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha c [...]
B3gnt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060247N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2; Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elon [...]
Zfp831 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060255Zinc finger protein 831.
Ier2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060275Immediate early response gene 2 protein; DNA-binding protein that seems to act as a transcription factor (By similarity). Involved in the regulation of neuronal differentiation, acts upon JNK-sig [...]
Adgrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060307Adhesion G-protein coupled receptor D1; Orphan receptor. Signals via G(s)-alpha family of G-proteins. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR [...]
Ccdc89 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060309Coiled-coil domain-containing protein 89; Belongs to the CCDC89 family.
Olfr730 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060325Olfactory receptor.
Swsap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060331ATPase SWSAP1; ATPase which is preferentially stimulated by single-stranded DNA and is involved in homologous recombination repair (HRR). Has a DNA-binding activity which is independent of its AT [...]
Dlst protein networkhttps://string-db.org/network/10090.ENSMUSP000000603462-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase); Dihydrolipoamide succinyltransferase (E2) component of the 2- oxoglutarate dehydrogenase complex (By similarity). [...]
Camk2n1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060349Calcium/calmodulin-dependent protein kinase II inhibitor 1; Potent and specific inhibitor of CaM-kinase II (CAMK2).
2510002D24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000060363UPF0545 protein C22orf39 homolog; Belongs to the UPF0545 family.
Pdik1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000060381Serine/threonine-protein kinase PDIK1L.
Rcan1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060394Calcipressin-1; Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. Belongs [...]
Patl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060398Protein PAT1 homolog 1; RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and [...]
Ecm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060402Extracellular matrix protein 2; Promotes matrix assembly and cell adhesiveness. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
Ucn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060405Urocortin-2; Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress (By similarity); Belon [...]
Mrgprg protein networkhttps://string-db.org/network/10090.ENSMUSP00000060411Mas-related G-protein coupled receptor member G; Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain; Belongs to the G-protein coup [...]
Krtcap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060414Keratinocyte-associated protein 3; Belongs to the TMEM54 family.
Odf3l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060418Outer dense fiber protein 3-like protein 1; Belongs to the ODF3 family.
Cdc37l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060421Hsp90 co-chaperone Cdc37-like 1; Co-chaperone that binds to numerous proteins and promotes their interaction with Hsp70 and Hsp90; Belongs to the CDC37 family.
Ube2dnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060423Ubiquitin-conjugating enzyme E2D N-terminal-like 1; Belongs to the ubiquitin-conjugating enzyme family.
Dbx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060424Developing brain homeobox 2.
Shb protein networkhttps://string-db.org/network/10090.ENSMUSP00000060433SH2 domain-containing adapter protein B; Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in [...]
Upp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060437Uridine phosphorylase 2; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as [...]
Dmrta2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060441Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development; Belongs to the DMRT family.
Car5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000060457Carbonic anhydrase 5A, mitochondrial; Reversible hydration of carbon dioxide. Low activity.
Hacd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060462Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, [...]
Shisal2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000060463Protein shisa-like-2A.
Lect2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060495Leukocyte cell-derived chemotaxin-2; Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation.
Samd10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060499Sterile alpha motif domain-containing protein 10.
Adam30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060505A disintegrin and metallopeptidase domain 30.
Fndc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060509Fibronectin type III domain-containing protein 9.
Galr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060517Galanin receptor type 3; Receptor for the hormone galanin and spexin-1.
Rps27rt protein networkhttps://string-db.org/network/10090.ENSMUSP0000006052340S ribosomal protein S27; Component of the small ribosomal subunit (By similarity). Required for proper rRNA processing and maturation of 18S rRNAs (By similarity).
Cyp2d40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060524Cytochrome P450, family 2, subfamily d, polypeptide 40; Belongs to the cytochrome P450 family.
Olfr683 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060527Olfactory receptor MOR40-1.
Cmtr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060558Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2; S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Met [...]
Cyp2c70 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060584Cytochrome P450 2C70; A cytochrome P450 monooxygenase involved in muricholic acid (MCA) synthesis. Hydroxylates at the 6-beta position two major bile acids, chenodeoxycholic acid (CDCA) and ursod [...]
Slc35d3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060589Solute carrier family 35 member D3; May play a role in hemostasis as a regulator of the biosynthesis of platelet-dense granules.
Gpr119 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060591Glucose-dependent insulinotropic receptor; Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulin [...]
Olfr1255 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060602Olfactory receptor.
Wdr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060613WD repeat-containing protein 3.
Prok1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060617Prokineticin-1; Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cell [...]
Aqp12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060622Aquaporin-12; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes; Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
Slc9b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060640Sodium/hydrogen exchanger 9B2; Na(+)/H(+) antiporter that extrudes Na(+) or Li(+) in exchange for external protons across the membrane. Contributes to the regulation of intracellular pH, sodium h [...]
Epha5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060646Ephrin type-A receptor 5; Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling [...]
Apol10a protein networkhttps://string-db.org/network/10090.ENSMUSP00000060650Apolipoprotein L 10A.
Tead1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060671Transcriptional enhancer factor TEF-1; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting pr [...]
Kcns3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060706Potassium voltage-gated channel subfamily S member 3; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulat [...]
Snip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060721Smad nuclear-interacting protein 1; Required for pre-mRNA splicing as component of the spliceosome. Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved i [...]
Lxn protein networkhttps://string-db.org/network/10090.ENSMUSP00000060732Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4 (By similarity). May play a role in inflammation. Belongs to the protease inhibitor I47 (latexin) family.
Vmn1r67 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060746Vomeronasal type-1 receptor.
Olfr70 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060748Olfactory receptor.
Llgl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060749Lethal(2) giant larvae protein homolog 1; Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic sp [...]
H1f10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060761H1 histone family, member X.
Kbtbd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060768Kelch repeat and BTB (POZ) domain-containing 7.
Crb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060769Protein crumbs homolog 1; Plays a role in photoreceptor morphogenesis in the retina. May maintain cell polarization and adhesion. Isoform 3 could play a role in epidermal tissue morphogenesis. Ma [...]
Rin3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060771Ras and Rab interactor 3; Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function [...]
Pdha2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060774Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), an [...]
Cxcr6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060776C-X-C chemokine receptor type 6; Receptor for the C-X-C chemokine CXCL16.
Lyrm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060779LYR motif-containing protein 4; Required for nuclear and mitochondrial iron-sulfur protein biosynthesis; Belongs to the complex I LYR family.
Pnma1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060783Paraneoplastic antigen Ma1 homolog; Belongs to the PNMA family.
Olfr159 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060784Olfactory receptor.
Hilpda protein networkhttps://string-db.org/network/10090.ENSMUSP00000060791Hypoxia-inducible lipid droplet-associated protein; Increases intracellular lipid accumulation. Stimulates expression of cytokines including IL6, MIF and VEGFA. Enhances cell growth and prolifera [...]
Pou4f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060798POU domain, class 4, transcription factor 1; Multifunctional transcription factor with different regions mediating its different effects. Acts by binding (via its C-terminal domain) to sequences [...]
Prr11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060803Proline-rich protein 11; Plays a critical role in cell cycle progression.
Glra2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060827Glycine receptor subunit alpha-2; Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and bet [...]
Gchfr protein networkhttps://string-db.org/network/10090.ENSMUSP00000060835GTP cyclohydrolase 1 feedback regulatory protein; Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine (By similarity).
Defb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060836Beta-defensin 6; Has potent antibacterial activity against E.coli (ATCC 25922); Belongs to the beta-defensin family.
Olfr456 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060839Olfactory receptor.
Irs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060844Insulin receptor substrate-3.
Dleu7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060855Leukemia-associated protein 7 homolog.
9030025P20Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000060857RIKEN cDNA 9030025P20 gene.
Polr1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000060858DNA-directed RNA polymerase I subunit RPA1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalyt [...]
Tmem252 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060863Transmembrane protein 252.
Cox7b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060890Cytochrome c oxidase subunit VIIb2.
Emc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060892ER membrane protein complex subunit 6; Belongs to the EMC6 family.
Gpr149 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060893Probable G-protein coupled receptor 149; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Defb12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060899Beta-defensin 12; Has antibacterial activity.
Trnt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060900CCA tRNA nucleotidyltransferase 1, mitochondrial; Adds and repairs the conserved 3'-CCA sequence necessary for the attachment of amino acids to the 3' terminus of tRNA molecules, using CTP and AT [...]
Sbk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060907Serine/threonine-protein kinase SBK1; May be involved in signal-transduction pathways related to the control of brain development; Belongs to the protein kinase superfamily. Ser/Thr protein kinas [...]
Gulo protein networkhttps://string-db.org/network/10090.ENSMUSP00000060912L-gulonolactone oxidase; Oxidizes L-gulono-1,4-lactone to hydrogen peroxide and L- xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate. Belongs to the oxygen-dependent FAD-linked o [...]
Cdc42ep1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060930Cdc42 effector protein 1; Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts (By similarity); Belongs to the BORG/CEP family.
Rtn4ip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060940Reticulon-4-interacting protein 1, mitochondrial; Plays a role in the regulation of retinal ganglion cell (RGC) neurite outgrowth, and hence in the development of the inner retina and optic nerve [...]
Rnf214 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060941RING finger protein 214.
Olfm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060985Noelin-3.
Defb13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000060997Beta-defensin 13; Has antibacterial activity.
Hmgn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061012Non-histone chromosomal protein HMG-14; Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which [...]
Insm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061046Insulinoma-associated protein 2; May function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.
Gprc5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000061062Retinoic acid-induced protein 3; Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR provides evide [...]
Leng9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061079Leukocyte receptor cluster member 9.
Pcdhb13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061087Protocadherin beta 13.
Mtap protein networkhttps://string-db.org/network/10090.ENSMUSP00000061092S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of M [...]
Kdm5d protein networkhttps://string-db.org/network/10090.ENSMUSP00000061095Lysine-specific demethylase 5D; Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', [...]
Tmem130 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061100Transmembrane protein 130.
Synb protein networkhttps://string-db.org/network/10090.ENSMUSP00000061107Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties. Together with Syna, participates in trophoblast fusion and the formation of a sy [...]
Gm49486 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061125Galectin.
Cyp4a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061126Cytochrome P450 4A10; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a va [...]
Lkaaear1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061134Protein LKAAEAR1.
Ghsr protein networkhttps://string-db.org/network/10090.ENSMUSP00000061153Growth hormone secretagogue receptor type 1; Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) ( [...]
Rps19bp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061167Active regulator of SIRT1; Direct regulator of SIRT1. Enhances SIRT1-mediated deacetylation of p53/TP53, thereby participating in inhibition of p53/TP53-mediated transcriptional activity (By simi [...]
Ankrd23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061168Ankyrin repeat domain-containing protein 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression [...]
Lamp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061180Lysosome-associated membrane glycoprotein 5; Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain; Belongs to the LAMP family.
Crh protein networkhttps://string-db.org/network/10090.ENSMUSP00000061185Corticoliberin; Hormone regulating the release of corticotropin from pituitary gland. Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile.
Olfr1008 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061191Olfactory receptor MOR187-3.
Sirpb1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000061216Signal-regulatory protein beta 1C.
Mindy4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061221Probable ubiquitin carboxyl-terminal hydrolase MINDY-4; Probable hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.
Pgm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061227Phosphoglucomutase-1; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family.
Mettl21c protein networkhttps://string-db.org/network/10090.ENSMUSP00000061229Protein-lysine methyltransferase METTL21C; Protein-lysine methyltransferase.
Irf2bp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061234Interferon regulatory factor 2-binding protein 1; Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as a [...]
Gpr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061243G-protein coupled receptor 4; Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production.
H2bc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061247H2B clustered histone 6.
D17H6S53E protein networkhttps://string-db.org/network/10090.ENSMUSP00000061264Uncharacterized protein C6orf47 homolog.
Ppm1e protein networkhttps://string-db.org/network/10090.ENSMUSP00000061278Protein phosphatase 1E; Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin [...]
Slc35g1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061282Solute carrier family 35 member G1; May play a role in intracellular calcium sensing and homeostasis. May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing ca [...]
P2ry10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061296Putative P2Y purinoceptor 10; Putative receptor for purines coupled to G-proteins.
Fbxl7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061305F-box/LRR-repeat protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex. During mitosis, it mediates the ubiquitination and subsequent p [...]
Tpcn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061308Two pore calcium channel protein 2; Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal [...]
Vps53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061317Vacuolar protein sorting-associated protein 53 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TG [...]
Lca5l protein networkhttps://string-db.org/network/10090.ENSMUSP00000061337Lebercilin-like protein.
Mei4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061341Meiosis-specific protein MEI4; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with IHO1/CCDC36 and R [...]
Brox protein networkhttps://string-db.org/network/10090.ENSMUSP00000061345BRO1 domain-containing protein BROX.
1810024B03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000061355RIKEN cDNA 1810024B03 gene.
Jkamp protein networkhttps://string-db.org/network/10090.ENSMUSP00000061370JNK1/MAPK8-associated membrane protein; May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) [...]
Tob2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061390Protein Tob2; Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases.
Cdcp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061401CUB domain-containing protein 2.
Ppp1r3d protein networkhttps://string-db.org/network/10090.ENSMUSP00000061402Protein phosphatase 1, regulatory subunit 3D.
Olig1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061408Oligodendrocyte transcription factor 1; Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neur [...]
Gpr18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061410N-arachidonyl glycine receptor; Receptor for endocannabinoid N-arachidonyl glycine (NAGly) (By similarity). However, conflicting results about the role of NAGly as an agonist are reported. Can al [...]
Susd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061423Sushi domain-containing protein 3.
Nog protein networkhttps://string-db.org/network/10090.ENSMUSP00000061427Noggin; Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somi [...]
Lyrm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061451LYR motif-containing protein 2; Belongs to the complex I LYR family.
Tmtc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061470Protein O-mannosyl-transferase TMTC3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl- transferases dedicated pr [...]
Srsf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061474Serine/arginine-rich splicing factor 4; Plays a role in alternative splice site selection during pre- mRNA splicing. Represses the splicing of MAPT/Tau exon 10 (By similarity); Belongs to the spl [...]
Gphb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061488Glycoprotein hormone beta-5; Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP prod [...]
Eea1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061493Early endosome antigen 1; Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.
Gal3st3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061517Galactose-3-O-sulfotransferase 3; Transfers a sulfate to position 3 of non-reducing beta- galactosyl residues in N-glycans and core2-branched O-glycans. Has high activity towards Gal-beta-1,4-Glc [...]
Zfp322a protein networkhttps://string-db.org/network/10090.ENSMUSP00000061524Zinc finger protein 322; Transcriptional activator. Important for maintenance of pluripotency in embryonic stem cells. Binds directly to the POU5F1 distal enhancer and the NANOG proximal promoter [...]
Cdcp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061529Putative DMBT1-like protein.
Defb10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061533Beta-defensin 10; Has antibacterial activity.
Kdm6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000061539Lysine-specific demethylase 6A; Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethyla [...]
Cilp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061544Cartilage intermediate layer protein 2 C1; May play a role in cartilage scaffolding.
Nkrf protein networkhttps://string-db.org/network/10090.ENSMUSP00000061546NF-kappa-B-repressing factor; Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK- kappa-B responsive genes. Involved [...]
Glp2r protein networkhttps://string-db.org/network/10090.ENSMUSP00000061560Glucagon-like peptide 2 receptor; This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity).
Olfr685 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061561Olfactory receptor.
Ttc24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061571Tetratricopeptide repeat protein 24.
Lypd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061578Ly6/PLAUR domain-containing protein 6; Acts as a modulator of nicotinic acetylcholine receptors (nAChRs) function in the brain. Enhances nicotine-induced Ca(2+) influx through nAChRs. Acts as a p [...]
Lmod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061597Leiomodin-1; Mediates nucleation of actin filaments.
Mfsd6l protein networkhttps://string-db.org/network/10090.ENSMUSP00000061601Major facilitator superfamily domain-containing protein 6-like.
Eogt protein networkhttps://string-db.org/network/10090.ENSMUSP00000061610EGF domain-specific O-linked N-acetylglucosamine transferase; Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins res [...]
Rabgap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061624Rab GTPase-activating protein 1; May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in [...]
Kdm4d protein networkhttps://string-db.org/network/10090.ENSMUSP00000061632Lysine-specific demethylase 4D; Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', [...]
Trarg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061634Trafficking regulator of GLUT4 1; Regulates insulin-mediated adipose tissue glucose uptake and transport by modulation of SLC2A4 recycling. Not required for SLC2A4 membrane fusion upon an initial [...]
Crppa protein networkhttps://string-db.org/network/10090.ENSMUSP00000061646D-ribitol-5-phosphate cytidylyltransferase; Cytidylyltransferase required for protein O-linked mannosylation (By similarity). Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribito [...]
Olfr1362 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061660Olfactory receptor.
Olfr1302 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061674Olfactory receptor.
Map10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061679Microtubule-associated protein 10; Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization o [...]
Otos protein networkhttps://string-db.org/network/10090.ENSMUSP00000061683Otospiralin; May be essential for the survival of the neurosensory epithelium of the inner ear.
Pskh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061700Serine/threonine-protein kinase H1; May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors [...]
Emid1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061704EMI domain-containing protein 1.
Krtap13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061716Putative keratin-associated protein.
Vill protein networkhttps://string-db.org/network/10090.ENSMUSP00000061731Villin-like protein; Possible tumor suppressor.
Kctd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061734BTB/POZ domain-containing protein KCTD4.
Fastkd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061737FAST kinase domain-containing protein 3, mitochondrial; Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND [...]
Gja10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061742Gap junction alpha-10 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to [...]
F2r protein networkhttps://string-db.org/network/10090.ENSMUSP00000061754Proteinase-activated receptor 1; High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
Gprc5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000061760G-protein coupled receptor family C group 5 member C; This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G- protein signaling [...]
Olfr620 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061764Olfactory receptor.
Rps6kc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061769Ribosomal protein S6 kinase delta-1; May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. Plays a role in the recruitment of PRDX3 to early endosomes.
Chtop protein networkhttps://string-db.org/network/10090.ENSMUSP00000061800Chromatin target of PRMT1 protein; Plays an important role in the ligand-dependent activation of estrogen receptor target genes (By similarity). May play a role in the silencing of fetal globin g [...]
Gdpgp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061808GDP-D-glucose phosphorylase 1; Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.
Lrtm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061828Leucine-rich repeat and transmembrane domain-containing protein 1.
9930012K11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000061834Uncharacterized protein C8orf58 homolog.
N6amt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061835Methyltransferase N6AMT1; Methyltransferase that can methylate both proteins and DNA, and to a lower extent, arsenic. Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5- methylat [...]
Fat4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061836Protocadherin Fat 4; Cadherins are cell-cell interaction molecules. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell pro [...]
Ubn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061843Ubinuclein-1; Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. [...]
Ahcy protein networkhttps://string-db.org/network/10090.ENSMUSP00000061851Adenosylhomocysteinase; Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in [...]
Tceal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061875Transcription elongation factor A protein-like 1; May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. Does not bi [...]
Insig1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061877Insulin-induced gene 1 protein; Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding protein [...]
Mrgprb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061878Mas-related G-protein coupled receptor member B2; Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a bas [...]
Ift43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061891Intraflagellar transport protein 43 homolog; As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPC [...]
Abi3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061893ABI gene family member 3; Inhibits ectopic tumor cell metastasis of SRD cells. In vitro, reduces cell motility; Belongs to the ABI family.
Zbtb40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061899Zinc finger and BTB domain-containing 40.
Ifi209 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061900Pyrin and HIN domain-containing protein 1.
Lrrc24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061906Leucine-rich repeat-containing protein 24.
Lsm10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061913U7 snRNA-associated Sm-like protein LSm10; Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing (By similarity). Increases U7 snRNA levels but not histone 3'- [...]
Tmtc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061919Protein O-mannosyl-transferase TMTC2; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl- transferases dedicated pr [...]
Mcm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061923DNA replication licensing factor MCM2; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiat [...]
D030056L22Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000061933Uncharacterized protein C9orf40 homolog.
Epcam protein networkhttps://string-db.org/network/10090.ENSMUSP00000061935Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epitheliu [...]
Phka1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061991Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha cha [...]
Mfsd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000061997Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily.
Rnf182 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062005E3 ubiquitin-protein ligase RNF182; E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway. Plays also a role i [...]
Fam3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000062006Protein FAM3B; Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner; Belongs to the FAM3 family.
Svs3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000062011Seminal vesicle secretory protein 3B.
B4gat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062016Beta-1,4-glucuronyltransferase 1; Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor [...]
Clec2m protein networkhttps://string-db.org/network/10090.ENSMUSP00000062024C-type lectin domain family 2, member m.
Zrsr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062025U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1; Plays a role in splicing of the U12-type introns. Implicated also in removal of U2 introns positioned adjacen [...]
H1f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062030Histone H1.1; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucle [...]
Acer1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062037Alkaline ceramidase 1; Endoplasmic reticulum ceramidase that catalyzes the hydrolysis of ceramides into sphingosine and free fatty acids at alkaline pH. Ceramides, sphingosine, and its phosphoryl [...]
Ndufaf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062039NADH dehydrogenase (ubiquinone) complex I, assembly factor 6; Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages. May play a role in the [...]
Cldn14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062045Claudin-14; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Cox19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062046Cytochrome c oxidase assembly protein COX19; Required for the transduction of an SCO1-dependent redox signal from the mitochondrion to ATP7A to regulate cellular copper homeostasis. May be requir [...]
Uaca protein networkhttps://string-db.org/network/10090.ENSMUSP00000062047Uveal autoantigen with coiled-coil domains and ankyrin repeats; Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulat [...]
Cit protein networkhttps://string-db.org/network/10090.ENSMUSP00000062049Citron Rho-interacting kinase; Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Probable RHO/RAC effector that binds to the GTP-bound forms of RHO [...]
Ubqln5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062054Ubiquilin 5.
2310061N02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000062074RIKEN cDNA 2310061N02 gene.
Dntt protein networkhttps://string-db.org/network/10090.ENSMUSP00000062078DNA nucleotidylexotransferase; [Isoform TDT-S]: Transferase that catalyzes the nontemplated addition of nucleoside triphosphate to coding ends during V(D)J recombination (N addition). Involved in [...]
Sntn protein networkhttps://string-db.org/network/10090.ENSMUSP00000062092Sentan; May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules.
Tlr6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062096Toll-like receptor 6; Participates in the innate immune response to Gram-positive bacteria and fungi. Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides. In resp [...]
Teddm1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000062098Transmembrane epididymal protein 1A.
Il17re protein networkhttps://string-db.org/network/10090.ENSMUSP00000062103Interleukin-17 receptor E; Specific functional receptor for IL17C, signaling through the NF-kappa-B and MAPK pathways. Requires TRAF3IP2 /ACT1 for signaling. Crucial regulator in innate immunity [...]
Gimap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062108GTPase IMAP family member 1; May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GT [...]
Otop2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062109Proton channel OTOP2; Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellu [...]
Tapt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062110Transmembrane anterior posterior transformation protein 1; Plays a role in primary cilia formation (By similarity). May act as a downstream effector of HOXC8 possibly by transducing or transmitti [...]
9530077C05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000062120Uncharacterized protein KIAA0895.
Tecrl protein networkhttps://string-db.org/network/10090.ENSMUSP00000062122Trans-2,3-enoyl-CoA reductase-like.
Lrrc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062158Leucine-rich repeat-containing protein 4; Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pa [...]
Flrt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062171Leucine-rich repeat transmembrane protein FLRT2; Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also [...]
Wdr37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062174WD repeat-containing protein 37.
Rtp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062178Receptor-transporting protein 2; Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs. Belongs to the TMEM7 family.
Has2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062212Hyaluronan synthase 2; Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most ex [...]
Prodh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062214Hydroxyproline dehydrogenase; Dehydrogenase that converts trans-4-L-hydroxyproline to delta-1-pyrroline-3-hydroxy-5-carboxylate (Hyp) using ubiquinone-10 as the terminal electron acceptor. Can al [...]
Ofcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062217Orofacial cleft 1 candidate gene 1 protein homolog.
Samd14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062231Sterile alpha motif domain-containing protein 14.
Lhfpl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062239LHFPL tetraspan subfamily member 2 protein; Plays a role in female and male fertility. Involved in distal reproductive tract development.
Spata46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062245Spermatogenesis-associated protein 46; Plays a role in spermiogenesis and fertilization.
Adrb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062256Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epin [...]
Trim32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062277E3 ubiquitin-protein ligase TRIM32; Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin). May ubiquitinate BBS2 (By similarity). Ubiquitinates PIAS4/PIASY and promotes its degrad [...]
Casc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062279Protein CASC1; Belongs to the CASC1 family.
Grin2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000062284Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sens [...]
2510009E07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000062303UPF0524 protein C3orf70 homolog; May play a role in neuronal and neurobehavioral development.
Liph protein networkhttps://string-db.org/network/10090.ENSMUSP00000062310Lipase member H; Hydrolyzes specifically phosphatidic acid (PA) to produce lysophosphatidic acid (LPA); Belongs to the AB hydrolase superfamily. Lipase family.
Upk3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000062312Uroplakin-3b; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoske [...]
Gja4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062320Gap junction alpha-4 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a [...]
Mrps27 protein networkhttps://string-db.org/network/10090.ENSMUSP0000006232628S ribosomal protein S27, mitochondrial; RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondria [...]
Hpdl protein networkhttps://string-db.org/network/10090.ENSMUSP000000623274-hydroxyphenylpyruvate dioxygenase-like protein; May have dioxygenase activity; Belongs to the 4HPPD family.
Tgfbr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062333TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokine [...]
Slc12a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062337Solute carrier family 12 member 8; Cation/chloride cotransporter that may play a role in the control of keratinocyte proliferation.
Mtmr11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062341Myotubularin-related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.
E4f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062344Transcription factor E4F1; May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin- associated TP53. Functions in cell survival [...]
Eid2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062345EP300-interacting inhibitor of differentiation 2; Interacts with EP300 and acts as a repressor of MYOD- dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferas [...]
2310057N15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000062370RIKEN cDNA 2310057N15 gene.
Pheta1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062386Sesquipedalian-1; Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
Prkca protein networkhttps://string-db.org/network/10090.ENSMUSP00000062392Protein kinase C alpha type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell prol [...]
C77080 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062395Uncharacterized protein KIAA1522.
Ifi205 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062409Interferon-activable protein 205-A; May act as a transcriptional regulator in the myeloid lineage. Inhibits cell growth via p53/TP53 and RB1-dependent and independent pathways (By similarity); Be [...]
4930430F08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000062410Uncharacterized protein C12orf29 homolog.
Ccdc149 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062411Coiled-coil domain-containing 149.
Hoxd10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062412Homeobox protein Hox-D10; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posteri [...]
Sfswap protein networkhttps://string-db.org/network/10090.ENSMUSP00000062413Splicing factor, suppressor of white-apricot homolog; Plays a role as an alternative splicing regulator. Regulates its own expression at the level of RNA processing. Also regulates the splicing o [...]
Pmf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062420Polyamine-modulated factor 1; Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis (By similarity). May act as [...]
Rasip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062429Ras-interacting protein 1; Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GT [...]
Cep120 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062433Centrosomal protein of 120 kDa; Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nucl [...]
Clec4a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062441C-type lectin domain family 4, member a1.
Rbm33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062449RNA-binding protein 33.
Ppp1r13b protein networkhttps://string-db.org/network/10090.ENSMUSP00000062464Apoptosis-stimulating of p53 protein 1; Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53 (By similarity). Regulates TP53 by enhancing the DNA bindi [...]
Zc3hav1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000062475Zinc finger CCCH-type antiviral protein 1-like.
Mrpl50 protein networkhttps://string-db.org/network/10090.ENSMUSP0000006247639S ribosomal protein L50, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL50 family.
Lrrc75a protein networkhttps://string-db.org/network/10090.ENSMUSP00000062489Leucine-rich repeat-containing protein 75A.
E130308A19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000062493RIKEN cDNA E130308A19 gene.
Ccndbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062496Cyclin-D1-binding protein 1; May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and b [...]
Scn4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000062507Sodium channel subunit beta-4; Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage [...]
Gm43302 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062528Predicted gene 43302.
Gpr82 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062535Probable G-protein coupled receptor 82; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Pcp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062539Calmodulin regulator protein PCP4; Functions as a modulator of calcium-binding by calmodulin. Thereby, regulates calmodulin activity and the different processes it controls. For instance, may pla [...]
Ccdc137 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062540Coiled-coil domain-containing protein 137.
Scg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062556Secretogranin-2; Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
Actrt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062570Actin-related protein T1; Negatively regulates the Hedgehog (SHH) signaling. Binds to the promoter of the SHH signaling mediator, GLI1, and inhibits its expression; Belongs to the actin family.
Nucks1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062576Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1.
Ccr10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062588C-C chemokine receptor type 10; Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level.
Phf13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062590PHD finger protein 13; Modulates chromatin structure. Required for normal chromosome condensation during the early stages of mitosis. Required for normal chromosome separation during mitosis (By [...]
Ing1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062593Inhibitor of growth protein 1; Isoform 1 inhibits p53-dependent transcriptional activation and may function as an oncoprotein. Isoform 2 acts as a negative growth regulator by cooperating with p5 [...]
Cldn34c4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062601Claudin 34C4.
Pla2g4f protein networkhttps://string-db.org/network/10090.ENSMUSP00000062607Cytosolic phospholipase A2 zeta; Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Has higher enzyme activity for phosphatidylethanolamine [...]
Ppp1r16b protein networkhttps://string-db.org/network/10090.ENSMUSP00000062615Protein phosphatase 1 regulatory inhibitor subunit 16B; Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Protects th [...]
Dhx30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062622ATP-dependent RNA helicase DHX30; RNA-dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit (By similarity). Required for optimal function of th [...]
Lurap1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000062628Leucine rich adaptor protein 1-like.
Exph5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062632Exophilin-5; May act as Rab effector protein and play a role in vesicle trafficking.
Tram1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062635Translocating chain-associated membrane protein 1-like 1; Stimulatory or required for the translocation of secretory proteins across the ER membrane; Belongs to the TRAM family.
C2cd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062637C2 domain-containing protein 3; Component of the centrioles that acts as a positive regulator of centriole elongation. Promotes assembly of centriolar distal appendage, a structure at the distal [...]
Gabra3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062638Gamma-aminobutyric acid receptor subunit alpha-3; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor [...]
Fam76b protein networkhttps://string-db.org/network/10090.ENSMUSP00000062642Protein FAM76B.
Arxes1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062660Adipocyte-related X-chromosome expressed sequence 1.
Gfod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062662Glucose-fructose oxidoreductase domain-containing protein 1.
Pon2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062670Serum paraoxonase/arylesterase 2; Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters; Belongs to the paraoxonase family.
Ccr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062677C-C chemokine receptor type 4; High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidy [...]
Fam171b protein networkhttps://string-db.org/network/10090.ENSMUSP00000062702Protein FAM171B; Belongs to the FAM171 family.
Taar8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000062719Trace amine-associated receptor 8a; Orphan olfactory receptor specific for trace amines. Belongs to the G-protein coupled receptor 1 family.
Fam110b protein networkhttps://string-db.org/network/10090.ENSMUSP00000062734Protein FAM110B.
Rxfp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062741Relaxin-3 receptor 1; Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation (By similarity); Belongs to the G-protein coupled receptor 1 family.
Hnmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000062747Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
Irf2bp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062753Interferon regulatory factor 2-binding protein 2; Acts as a transcriptional corepressor in a IRF2-dependent manner, this repression is not mediated by histone deacetylase activities. Represses th [...]
Bmerb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062758bMERB domain-containing protein 1.
Sox18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062759Transcription factor SOX-18; Transcriptional activator that binds to the consensus sequence 5'-AACAAAG-3' in the promoter of target genes and plays an essential role in embryonic cardiovascular d [...]
Mterf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062762Transcription termination factor 2, mitochondrial; Binds mitochondrial DNA and plays a role in the regulation of transcription of mitochondrial mRNA and rRNA species.
Nupl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062766Nucleoporin NUP42; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm.
Rasef protein networkhttps://string-db.org/network/10090.ENSMUSP00000062771Ras and EF-hand domain-containing protein homolog; Binds predominantly GDP, and also GTP; Belongs to the small GTPase superfamily. Rab family.
Nap1l5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062780Nucleosome assembly protein 1-like 5.
Defb14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062781Beta-defensin 14; Has antibacterial activity; Belongs to the beta-defensin family.
Vav2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062782Guanine nucleotide exchange factor VAV2; Guanine nucleotide exchange factor for the Rho family of Ras- related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated [...]
Tssk6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062783Testis-specific serine/threonine-protein kinase 6; Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling.
Phxr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062790Putative per-hexamer repeat protein 2.
Sptssb protein networkhttps://string-db.org/network/10090.ENSMUSP00000062794Serine palmitoyltransferase small subunit B; Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrat [...]
Ttll13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062795Tubulin polyglutamylase TTLL13; Polyglutamylase which preferentially modifies alpha-tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initia [...]
Hscb protein networkhttps://string-db.org/network/10090.ENSMUSP00000062811Iron-sulfur cluster co-chaperone protein HscB, mitochondrial; Acts as a co-chaperone in iron-sulfur cluster assembly in both mitochondria and the cytoplasm. Required for incorporation of iron-sul [...]
Olfr645 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062821Olfactory receptor Olfr645.
Dppa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062832Developmental pluripotency-associated protein 3; Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA [...]
Lao1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062834Amine oxidase.
Erich3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062837Glutamate-rich 3.
Them4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062841Acyl-coenzyme A thioesterase THEM4; Has acyl-CoA thioesterase activity towards medium and long- chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid [...]
Mcmbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000062843Mini-chromosome maintenance complex-binding protein; Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes [...]
Pik3cg protein networkhttps://string-db.org/network/10090.ENSMUSP00000062864Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to gener [...]
Oc90 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062865Otoconin-90; Major protein of the otoconia, a calcium carbonate structure in the saccule and utricle of the ear. Together with OTOL1, acts as a scaffold for otoconia biomineralization: sequesters [...]
Gdf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062884Growth/differentiation factor 6; Growth factor that controls proliferation and cellular differentiation in the retina and bone formation. Plays a key role in regulating apoptosis during retinal d [...]
Morn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062887MORN repeat-containing protein 4; Plays a role in promoting axonal degeneration following neuronal injury by toxic insult or trauma.
Speer4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000062903Spermatogenesis associated glutamate (E)-rich protein 4b.
Tmprss11c protein networkhttps://string-db.org/network/10090.ENSMUSP00000062915Transmembrane protease serine 11C non-catalytic chain; Serine protease which has a preference for Arg or Lys in position P1 and uncharged residues in positions P2 and P3. Shows specificity toward [...]
Tas2r139 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062919Taste receptor type 2 member 39; Putative taste receptor which may play a role in the perception of bitterness.
Rtn4r protein networkhttps://string-db.org/network/10090.ENSMUSP00000062924Reticulon-4 receptor; Receptor for RTN4, OMG and MAG. Functions as receptor for the sialylated gangliosides GT1b and GM1. Besides, functions as receptor for chondroitin sulfate proteoglycans. Can [...]
Slbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000062930Histone RNA hairpin-binding protein; RNA-binding protein involved in the histone pre-mRNA processing. Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to e [...]
Olfr710 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062956Olfactory receptor.
Stkld1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062967Serine/threonine kinase-like domain-containing protein STKLD1.
Spink10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062976Serine protease inhibitor Kazal-type 10; Probable serine protease inhibitor.
Dcaf12l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062991DDB1- and CUL4-associated factor 12-like protein 1; Belongs to the WD repeat DCAF12 family.
Npas4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062992Neuronal PAS domain-containing protein 4; Transcription factor expressed in neurons of the brain that regulates the excitatory-inhibitory balance within neural circuits and is required for contex [...]
Dnah10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000062995Dynein, axonemal, heavy chain 10.
Il1f10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063004Interleukin-1 family member 10; Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T- cells in response to heat-killed C [...]
Ces2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000063005Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
AI467606 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063016Transmembrane protein C16orf54 homolog.
Mrgprd protein networkhttps://string-db.org/network/10090.ENSMUSP00000063021Mas-related G-protein coupled receptor member D; May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for [...]
Serpinb6d protein networkhttps://string-db.org/network/10090.ENSMUSP00000063025Serine (or cysteine) peptidase inhibitor, clade B, member 6d; Belongs to the serpin family.
Zfp459 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063027Zinc finger protein 459.
Tpra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063042Transmembrane protein adipocyte-associated 1.
Ccdc158 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063050Coiled-coil domain-containing protein 158.
Tspyl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063051Testis-specific Y-encoded-like protein 1.
Rab33b protein networkhttps://string-db.org/network/10090.ENSMUSP00000063054Ras-related protein Rab-33B; Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking (By similarity). It is involved in autophagy, acting as a modulato [...]
Pnma5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063061Paraneoplastic antigen-like protein 5.
Dlk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063104Protein delta homolog 1; May have a role in neuroendocrine differentiation. Inhibits adipocyte differentiation.
Bpifc protein networkhttps://string-db.org/network/10090.ENSMUSP00000063107BPI fold-containing family C protein.
Myoz3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063108Myozenin-3; Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin [...]
Prlhr protein networkhttps://string-db.org/network/10090.ENSMUSP00000063114Prolactin-releasing peptide receptor; Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing. Belongs to the G-protein coup [...]
Htr1f protein networkhttps://string-db.org/network/10090.ENSMUSP000000631365-hydroxytryptamine receptor 1F; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding cau [...]
Fam25c protein networkhttps://string-db.org/network/10090.ENSMUSP00000063140Protein FAM25C; Belongs to the FAM25 family.
Tmem125 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063157Transmembrane protein 125.
Zfand3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063158AN1-type zinc finger protein 3.
Prkaa1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000631665'-AMP-activated protein kinase catalytic subunit alpha-1; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular e [...]
March10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063198Membrane-associated ring-CH-type finger 10.
Taf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063201Transcription initiation factor TFIID subunit 8; Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. Mediates both basal [...]
Asap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063217Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive [...]
Lrrc29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063248Leucine-rich repeat-containing 29.
Tmcc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063264Transmembrane and coiled-coil domain protein 3; Belongs to the TEX28 family.
Ascc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063272Activating signal cointegrator 1 complex subunit 2; Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquiti [...]
Gabra5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063276Gamma-aminobutyric acid receptor subunit alpha-5; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor [...]
Cemip protein networkhttps://string-db.org/network/10090.ENSMUSP00000063277Cell migration-inducing and hyaluronan-binding protein; Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluron [...]
Arhgef33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063284Rho guanine nucleotide exchange factor 33.
Sprr2k protein networkhttps://string-db.org/network/10090.ENSMUSP00000063287Small proline-rich protein 2K; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane [...]
Akr1cl protein networkhttps://string-db.org/network/10090.ENSMUSP00000063309Aldo-keto reductase family 1, member C-like.
Acox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063325Peroxisomal acyl-CoA oxidase 1, A chain; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs (By similarity). Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and a [...]
Kcnj3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063329G protein-activated inward rectifier potassium channel 1; This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow [...]
Cgas protein networkhttps://string-db.org/network/10090.ENSMUSP00000063331Cyclic GMP-AMP synthase; Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP and plays a key role in innate immunity. Catalysis involves both the format [...]
Rcor2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063335REST corepressor 2; May act as a component of a corepressor complex that represses transcription.
Them7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063340Novel Thioesterase superfamily domain and Saposin A-type domain containing protein (0610012H03Rik).
Slc2a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063352Solute carrier family 2, facilitated glucose transporter member 9; Urate transporter, which may play a role in the urate reabsorption by proximal tubules. Does not transport glucose, fructose or [...]
1700016K19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000063358Protein LIAT1; May be involved in ATE1-mediated N-terminal arginylation.
Spinkl protein networkhttps://string-db.org/network/10090.ENSMUSP00000063376Serine protease inhibitor kazal-like protein, major form; Does not function as an inhibitor of trypsin, chymotrypsin, subtilisin or elastase. Binds sperm and enhances sperm motility. May act as a [...]
Kcnq3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063380Potassium voltage-gated channel subfamily KQT member 3; Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-cur [...]
Nrk protein networkhttps://string-db.org/network/10090.ENSMUSP00000063397Nik-related protein kinase; May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling [...]
Mtif3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063398Translation initiation factor IF-3, mitochondrial; IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subu [...]
Trim65 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063410Tripartite motif-containing protein 65.
Acox3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063412Peroxisomal acyl-coenzyme A oxidase 3; Oxidizes the CoA-esters of 2-methyl-branched fatty acids.
Acsm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063416Acyl-coenzyme A synthetase ACSM5, mitochondrial; Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism.
Cfap300 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063450Cilia- and flagella-associated protein 300; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm [...]
Slc35c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063461GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily.
Ncam2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063468Neural cell adhesion molecule 2; May play important roles in selective fasciculation and zone- to-zone projection of the primary olfactory axons.
1700013H16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000063474RIKEN cDNA 1700013H16 gene.
Fam229b protein networkhttps://string-db.org/network/10090.ENSMUSP00000063508Protein FAM229B; Belongs to the FAM229 family.
Dram2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063510DNA damage-regulated autophagy modulator protein 2; Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to pr [...]
Car8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063511Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family.
Opn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063542Opsin-5; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Abat protein networkhttps://string-db.org/network/10090.ENSMUSP000000635484-aminobutyrate aminotransferase, mitochondrial; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respective [...]
Gemin6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063554Gem-associated protein 6; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important r [...]
Nup107 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063590Nuclear pore complex protein Nup107; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to [...]
Mocos protein networkhttps://string-db.org/network/10090.ENSMUSP00000063609Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cof [...]
Clec12a protein networkhttps://string-db.org/network/10090.ENSMUSP00000063627C-type lectin domain family 12 member A; Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
Impg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063648Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and [...]
Dcdc2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000063650Doublecortin domain-containing protein 2; Protein that plays a role in the inhibition of canonical Wnt signaling pathway (By similarity). May be involved in neuronal migration during development [...]
Neo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063656Neogenin; Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. [...]
Ffar4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063660Free fatty acid receptor 4; Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega- 3 fatty acids and mediates robust a [...]
Lypd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063665LY6/PLAUR domain-containing 9.
Gpr17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063670Uracil nucleotide/cysteinyl leukotriene receptor; Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. Ma [...]
Plekho2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063677Pleckstrin homology domain-containing family O member 2.
C1ra protein networkhttps://string-db.org/network/10090.ENSMUSP00000063707Complement C1r-A subcomponent heavy chain; C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system; Belon [...]
Arhgdia protein networkhttps://string-db.org/network/10090.ENSMUSP00000063714Rho GDP-dissociation inhibitor 1; Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequen [...]
Fut2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063719Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a [...]
Ezr protein networkhttps://string-db.org/network/10090.ENSMUSP00000063734Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical p [...]
Tas2r137 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063743Taste receptor type 2 member 3; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calciu [...]
Vps37d protein networkhttps://string-db.org/network/10090.ENSMUSP00000063762Vacuolar protein sorting-associated protein 37D; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into mu [...]
Adcyap1r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063784Pituitary adenylate cyclase-activating polypeptide type I receptor; This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl c [...]
Irs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063795Insulin receptor substrate 1; May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins contain [...]
Ifng protein networkhttps://string-db.org/network/10090.ENSMUSP00000063800Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent [...]
Rab39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063804Ras-related protein Rab-39A; Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Play [...]
Gabrg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063812Gamma-aminobutyric acid receptor subunit gamma-2; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. [...]
Pcx protein networkhttps://string-db.org/network/10090.ENSMUSP00000063825Pyruvate carboxylase, mitochondrial; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transf [...]
Adam10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063839Disintegrin and metalloproteinase domain-containing protein 10; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble [...]
Bcl2a1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000063842B-cell leukemia/lymphoma 2 related protein A1c.
Kansl1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000063843KAT8 regulatory NSL complex subunit 1-like protein.
Fbrsl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063879Fibrosin-like 1.
Lrtm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063882Leucine-rich repeat and transmembrane domain-containing protein 2.
Glrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063883Glutamine repeat protein 1.
Slc24a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063887Sodium/potassium/calcium exchanger 5; Cation exchanger involved in pigmentation, possibly by participating in ion transport in melanosomes. Predominant sodium- Calcium exchanger in melanocytes. P [...]
Eif2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000063894Eukaryotic translation initiation factor 2D; Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tR [...]
Nanp protein networkhttps://string-db.org/network/10090.ENSMUSP00000063895N-acylneuraminate-9-phosphatase; Belongs to the HAD-like hydrolase superfamily. NANP family.
Gpr20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063910G-protein coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP.
Lrrc56 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063912Leucine-rich repeat-containing protein 56; Required for the assembly of dynein arms.
Fam204a protein networkhttps://string-db.org/network/10090.ENSMUSP00000063913Protein FAM204A.
Chl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063933Processed neural cell adhesion molecule L1-like protein; Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble an [...]
Tas2r130 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063954Taste receptor type 2 member 7; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calciu [...]
Mbd3l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063957Methyl-CpG-binding domain protein 3-like 1; Transcriptional repressor.
Tmem150a protein networkhttps://string-db.org/network/10090.ENSMUSP00000063977Transmembrane protein 150A; Regulates localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane, possibly by reducing the association of TTC7 (TTC7A or TTC7B) with the PI4K comp [...]
Kidins220 protein networkhttps://string-db.org/network/10090.ENSMUSP00000063999Kinase D-interacting substrate 220.
Mogat2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000640412-acylglycerol O-acyltransferase 2; Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty a [...]
Ptprn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064046Receptor-type tyrosine-protein phosphatase N2; Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreati [...]
Ptprs protein networkhttps://string-db.org/network/10090.ENSMUSP00000064048Receptor-type tyrosine-protein phosphatase S; Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to cho [...]
Tcaf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064060TRPM8 channel-associated factor 3; May play a role in the regulation of the cation channel TRPM8 activity.
Tmem200a protein networkhttps://string-db.org/network/10090.ENSMUSP00000064080Transmembrane protein 200A.
Vmn1r236 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064103Vomeronasal type-1 receptor.
Vmac protein networkhttps://string-db.org/network/10090.ENSMUSP00000064120Vimentin-type intermediate filament-associated coiled-coil protein.
Ppp1r14b protein networkhttps://string-db.org/network/10090.ENSMUSP00000064129Protein phosphatase 1 regulatory subunit 14B; Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated.
Gpc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064131Glypican-3 alpha subunit; Cell surface proteoglycan that bears heparan sulfate (By similarity). Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell su [...]
Tescl protein networkhttps://string-db.org/network/10090.ENSMUSP00000064132Tescalcin-like.
Rft1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064153Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmi [...]
Rpia protein networkhttps://string-db.org/network/10090.ENSMUSP00000064158Ribose-5-phosphate isomerase.
Btnl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064161Butyrophilin, subfamily 3, member A3.
Flnc protein networkhttps://string-db.org/network/10090.ENSMUSP00000064163Filamin-C; Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskele [...]
Rbm12b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064195RNA-binding protein 12B-A.
Lypla2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064204Acyl-protein thioesterase 2; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoyla [...]
1700024B05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000064211RIKEN cDNA 1700024B05 gene.
Dmrtb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064220Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family.
Zfp277 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064226Zinc finger protein 277.
Apol8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064237Apolipoprotein L 8.
Cd48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064241CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.
Chst1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064246Carbohydrate sulfotransferase 1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of galactose (Gal) resid [...]
Kif2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000064261Kinesin-like protein KIF2C; In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore [...]
Dlg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064280Disks large homolog 1; Essential multidomain scaffolding protein required for normal development. Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polar [...]
Atpif1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064282ATPase inhibitor, mitochondrial; Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts [...]
Spata18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064308Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochond [...]
Tmem62 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064310Transmembrane protein 62.
Pank4 protein networkhttps://string-db.org/network/10090.ENSMUSP000000643304'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively da [...]
Exoc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064332Exocyst complex component 6; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Together with RAB11A, RAB3IP, RAB8A, PARD3, PR [...]
Wnt11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064333Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete r [...]
Tnrc6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000064336Trinucleotide repeat-containing gene 6B protein; Plays a role in RNA-mediated gene silencing by both micro- RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA- dependent transl [...]
Klf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064366Krueppel-like factor 1; Transcription regulator of erythrocyte development. Binds to the CACCC box in the beta-globin gene promoter and activates transcription. Probably serves as a general switc [...]
S100a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064385Protein S100-A8; S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis an [...]
Ptprr protein networkhttps://string-db.org/network/10090.ENSMUSP00000064392Receptor-type tyrosine-protein phosphatase R; Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephos [...]
Dach2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064393Dachshund homolog 2; Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating prolifera [...]
Jak2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064394Tyrosine-protein kinase JAK2; Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling e [...]
Grm7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064404Metabotropic glutamate receptor 7; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G protein [...]
Kcmf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064410E3 ubiquitin-protein ligase KCMF1; Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination; Belongs to the KCMF1 family.
Arl13a protein networkhttps://string-db.org/network/10090.ENSMUSP00000064416ADP-ribosylation factor-like protein 13A; Belongs to the small GTPase superfamily.
Zfp395 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064422Zinc finger protein 395.
Slitrk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064443SLIT and NTRK-like protein 4; It is involved in synaptogenesis and promotes synapse differentiation (By similarity). Suppresses neurite outgrowth.
Calhm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064462Calcium homeostasis modulator protein 5; Pore-forming subunit of a voltage-gated ion channel. Belongs to the CALHM family.
Espl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064465Separin; Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cel [...]
Rimklb protein networkhttps://string-db.org/network/10090.ENSMUSP00000064467Beta-citrylglutamate synthase B; Catalyzes the synthesis of beta-citryl-L-glutamate and N- acetyl-L-aspartyl-L-glutamate. Beta-citryl-L-glutamate is synthesized more efficiently than N-acetyl-L-a [...]
Unc93a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064469Unc-93 homolog A (C. elegans).
Wfdc21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064479Protein Wfdc21; May promote activation of the metalloproteinase MMP2.
Slc51b protein networkhttps://string-db.org/network/10090.ENSMUSP00000064494Organic solute transporter subunit beta; Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export [...]
Try5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064498Trypsinogen 9; Belongs to the peptidase S1 family.
Poglut2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064500Protein O-glucosyltransferase 2; Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. [...]
Tmem255a protein networkhttps://string-db.org/network/10090.ENSMUSP00000064511Transmembrane protein 255A; Belongs to the TMEM255 family.
Usp39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064515U4/U6.U5 tri-snRNP-associated protein 2; Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the precatalytic spliceosome. Regulates AURKB mR [...]
Lancl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064516LanC-like protein 3.
Ctnnd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064518Catenin delta-1; Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Be [...]
Artn protein networkhttps://string-db.org/network/10090.ENSMUSP00000064521Artemin; Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture [...]
Fam216b protein networkhttps://string-db.org/network/10090.ENSMUSP00000064524Protein FAM216B; Belongs to the FAM216 family.
Tmprss5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064527Transmembrane protease serine 5; May play a role in hearing.
Dnm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064538Dynamin-3; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, [...]
Pdlim1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064545PDZ and LIM domain protein 1; Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (By similarity). Involved in assembly, disassembly and [...]
Pigw protein networkhttps://string-db.org/network/10090.ENSMUSP00000064547Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol rin [...]
Defb34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064554Beta-defensin 34; Has antibacterial activity.
Angel2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064556Protein angel homolog 2.
Dnajc5g protein networkhttps://string-db.org/network/10090.ENSMUSP00000064587DnaJ heat shock protein family (Hsp40) member C5 gamma.
Gpr50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064608Melatonin-related receptor; Does not bind melatonin; Belongs to the G-protein coupled receptor 1 family.
Zfp180 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064611Zinc finger protein 180.
Gm5072 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064613Predicted gene 5072.
4930502E18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000064619Cancer/testis antigen 55.
Wdyhv1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064622Protein N-terminal glutamine amidohydrolase; Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Con [...]
Zfp24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064637Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinatin [...]
Sprr2e protein networkhttps://string-db.org/network/10090.ENSMUSP00000064652Small proline-rich protein 2E; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane [...]
Fabp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064655Fatty acid-binding protein, liver; Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, a [...]
Tas2r134 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064657Taste receptor type 2 member 134; Putative taste receptor which may play a role in the perception of bitterness.
Dcpp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064663Demilune cell and parotid protein 1.
Slc39a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064667Zinc transporter ZIP6; May act as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family.
Nudcd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064668NudC domain-containing protein 3.
Junb protein networkhttps://string-db.org/network/10090.ENSMUSP00000064680Transcription factor jun-B; Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'; Belongs to the bZIP [...]
Gfap protein networkhttps://string-db.org/network/10090.ENSMUSP00000064691Glial fibrillary acidic protein; GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other [...]
Vapb protein networkhttps://string-db.org/network/10090.ENSMUSP00000064699Vesicle-associated membrane protein-associated protein B; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium ho [...]
Cadps protein networkhttps://string-db.org/network/10090.ENSMUSP00000064706Calcium-dependent secretion activator 1; Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogen [...]
Slc8b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064714Mitochondrial sodium/calcium exchanger protein; Mitochondrial sodium/calcium antiporter that mediates sodium- dependent calcium efflux from mitochondrion, by mediating the exchange of 3 sodium io [...]
Dsg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064718Desmoglein-3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Efemp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064719EGF-containing fibulin-like extracellular matrix protein 2; Belongs to the fibulin family.
Phgdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000064755D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Doe [...]
Atl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064758Atlastin-2; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular netw [...]
Adm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064761Adrenomedullin-2; [Adrenomedullin-2]: May play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the [...]
Adarb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064775Double-stranded RNA-specific editase B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of bindi [...]
Wdr86 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064785WD repeat domain 86.
Tafa5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064808Chemokine-like protein TAFA-5; Acts as a chemokine-like protein by regulating cell proliferation and migration through activation of G protein-coupled receptors (GPCRs), such as S1PR2 and FPR2. S [...]
Slc22a26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064809Solute carrier family 22 (organic cation transporter), member 26.
Slfn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064819Schlafen family member 5; May have a role in hematopoietic cell differentiation.
Klf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064823Krueppel-like factor 2; Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription. Might be involved in tra [...]
Sytl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064826Synaptotagmin-like protein 5; May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids (By similarity).
Ttk protein networkhttps://string-db.org/network/10090.ENSMUSP00000064839Dual specificity protein kinase TTK; Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint (By simila [...]
Cnot10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064840CCR4-NOT transcription complex subunit 10; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA d [...]
Hbb-bh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064865Hemoglobin subunit beta-H1; This is an embryonic beta-type chain.
Sertm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064870Serine-rich and transmembrane domain-containing protein 1.
Wnt5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000064878Protein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4 [...]
Prrc2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000064892Protein PRRC2B.
Arfgap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064893ADP-ribosylation factor GTPase-activating protein 3; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from G [...]
Chst13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064897Carbohydrate sulfotransferase.
Sec31b protein networkhttps://string-db.org/network/10090.ENSMUSP00000064900Protein transport protein Sec31B; As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum.
Oosp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064913Oocyte-secreted protein 3; Belongs to the PLAC1 family.
Gid4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064926Glucose-induced degradation protein 4 homolog; Substrate-recognition subunit of the CTLH E3 ubiquitin- protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitina [...]
Socs6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064929Suppressor of cytokine signaling 6; SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of [...]
Cd177 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064934CD177 antigen; In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18, mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production (B [...]
Mlxip protein networkhttps://string-db.org/network/10090.ENSMUSP00000064943MLX-interacting protein; Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycoly [...]
Cwc22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064947Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding [...]
Susd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064961Sushi domain-containing protein 6; May play a role in growth-suppressive activity and cell death. May be involved in the production of chemokine molecules in umbilical vein endothelial cells (HUV [...]
Tm2d3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000064967TM2 domain-containing protein 3; Belongs to the TM2 family.
Synpr protein networkhttps://string-db.org/network/10090.ENSMUSP00000064986Synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity).
Purg protein networkhttps://string-db.org/network/10090.ENSMUSP00000065002Purine-rich element-binding protein gamma.
Gpatch2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065009G patch domain-containing protein 2; Enhances the ATPase activity of DHX15 in vitro.
Sec14l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065084SEC14-like 3 (S. cerevisiae).
Aldh7a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065089Alpha-aminoadipic semialdehyde dehydrogenase; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl don [...]
Rhobtb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065095Rho-related BTB domain-containing protein 1.
Galnt10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065096Polypeptide N-acetylgalactosaminyltransferase 10; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threo [...]
Defb21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065102Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
Suclg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065113Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of [...]
4930503L19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000065118Lung adenoma susceptibility protein 2; Might play a role in cell proliferation.
Lrguk protein networkhttps://string-db.org/network/10090.ENSMUSP00000065146Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspect [...]
Npy5r protein networkhttps://string-db.org/network/10090.ENSMUSP00000065157Neuropeptide Y receptor type 5; Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated [...]
Kif1bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000065160KIF-binding protein; Required for neuronal development and differentiation. Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central ne [...]
Nkapl protein networkhttps://string-db.org/network/10090.ENSMUSP00000065168NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis; Belongs to the NKAP family.
Ddx10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065198Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase.
Mepe protein networkhttps://string-db.org/network/10090.ENSMUSP00000065200Matrix extracellular phosphoglycoprotein; Regulates renal phosphate and uric acid excretion. Regulates bone mineralization by osteoblasts and cartilage mineralization by chondrocytes. Regulates t [...]
Adam12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065213Disintegrin and metalloproteinase domain-containing protein 12; Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells [...]
March2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065225E3 ubiquitin-protein ligase MARCHF2; E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesic [...]
Gtf2h2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065228General transcription factor IIH subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotid [...]
C2cd2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000065233Phospholipid transfer protein C2CD2L; Lipid-binding protein that transports phosphatidylinositol, the precursor of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), from its site of synthesis in [...]
Slc30a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065254Zinc transporter 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requi [...]
Mettl7a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065271Methyltransferase-like 7A1.
Cast protein networkhttps://string-db.org/network/10090.ENSMUSP00000065275Calpastatin; Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein deg [...]
Serpinb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065277Plasminogen activator inhibitor 2, macrophage; Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. Not required for norm [...]
P3h4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065278Endoplasmic reticulum protein SC65; Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly [...]
Abhd10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065282Mycophenolic acid acyl-glucuronide esterase, mitochondrial.
Ocln protein networkhttps://string-db.org/network/10090.ENSMUSP00000065284Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier; Belongs to the ELL/occludin family.
Klk13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065308Kallikrein-related-peptidase 13; Belongs to the peptidase S1 family.
Asna1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065337ATPase Asna1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA pro [...]
Krt73 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065349Keratin, type II cytoskeletal 73; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (By similarity).
Ndufa8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065352NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved [...]
Nfil3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065363Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and vi [...]
Kcnmb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065384Calcium-activated potassium channel subunit beta-4; Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, [...]
Prss2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065393Anionic trypsin-2.
Tceal5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065397Transcription elongation factor A protein-like 5; May be involved in transcriptional regulation; Belongs to the TFS-II family. TFA subfamily.
Tmem9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065409Transmembrane protein 9; May be involved in intracellular transport; Belongs to the TMEM9 family.
Clec16a protein networkhttps://string-db.org/network/10090.ENSMUSP00000065423Protein CLEC16A; Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PRKN pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. Th [...]
Rab7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000065456Ras-related protein Rab-7b; Controls vesicular trafficking from endosomes to the trans- Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, I [...]
Nyap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065468Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2; Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesi [...]
Dcst1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065502E3 ubiquitin-protein ligase DCST1; E3 ubiquitin-protein ligase which mediates 'Lys-48'-linked ubiquitination of STAT2 and induces its proteosomal degradation thereby negatively regulating type-I- [...]
Rgs9bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000065511Regulator of G-protein signaling 9-binding protein; Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via it [...]
Adam6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000065529A disintegrin and metallopeptidase domain 6B.
Gpr173 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065533Probable G-protein coupled receptor 173; Is a receptor for the SMIM20 derived peptides Phoenixin-14 and Phoenixin-20. It mediates the Phoenixin-14 and Phoenixin-20 augmentation of gonadotropin-re [...]
Chdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000065542Choline dehydrogenase, mitochondrial; Belongs to the GMC oxidoreductase family.
Azin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065544Antizyme inhibitor 1; Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that cou [...]
Rtkn protein networkhttps://string-db.org/network/10090.ENSMUSP00000065571Rhotekin; Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin str [...]
Cyp3a25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065585Cytochrome P450 3A25; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a va [...]
Bcl2a1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000065612B-cell leukemia/lymphoma 2 related protein A1b.
Fam49a protein networkhttps://string-db.org/network/10090.ENSMUSP00000065613Protein FAM49A; Belongs to the FAM49 family.
Rasgef1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000065619Ras-GEF domain-containing family member 1C; Guanine nucleotide exchange factor (GEF).
Zfp560 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065620Zinc finger protein 560.
Olfr284 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065626Olfactory receptor.
Slc16a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065628Monocarboxylate transporter 7; Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-cha [...]
Tpk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065631Thiamin pyrophosphokinase 1; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate.
Arhgap20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065633Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Taf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065645Transcription initiation factor TFIID subunit 7; Functions as a component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in [...]
Art2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000065658T-cell ecto-ADP-ribosyltransferase 2; Has both NAD(+) glycohydrolase and ADP-ribosyltransferase activity.
Foxi3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065664Forkhead box I3.
Kcnk18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065713Potassium channel subfamily K member 18; Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. May function as background potassium channel that sets [...]
Fate1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065715Fetal and adult testis-expressed transcript protein homolog; Involved in the regulation of endoplasmic reticulum (ER)- mitochondria coupling. Negatively regulates the ER-mitochondria distance and [...]
Plpp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065719Phospholipid phosphatase 3; Magnesium-independent phospholipid phosphatase of the plasma membrane that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate este [...]
Tbc1d22a protein networkhttps://string-db.org/network/10090.ENSMUSP00000065721TBC1 domain family member 22A; May act as a GTPase-activating protein for Rab family protein(s).
Cept1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065743Choline/ethanolaminephosphotransferase 1; Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP- ethanolamine, respectively. Involved in protein-de [...]
D430042O09Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000065744Protein KIAA0556; May influence the stability of microtubules (MT), possibly through interaction with the MT-severing katanin complex.
Sp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065746Transcription factor Sp8; Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgro [...]
Msra protein networkhttps://string-db.org/network/10090.ENSMUSP00000065754Mitochondrial peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reducti [...]
Slc30a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065764Zinc transporter 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 [...]
Ilf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065770Interleukin enhancer-binding factor 3; RNA-binding protein that plays an essential role in the biogenesis of circular RNAs (circRNAs) which are produced by back- splicing circularization of pre-m [...]
Adam39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065783A disintegrin and metallopeptidase domain 39.
Astn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065786Astrotactin-2; Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular tra [...]
Dnaic2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065787Dynein intermediate chain 2, axonemal; Part of the dynein complex of respiratory cilia.
Cyp2c67 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065796Cytochrome P450, family 2, subfamily c, polypeptide 67; Belongs to the cytochrome P450 family.
Smad5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065798Mothers against decapentaplegic homolog 5; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor- regulated SMAD (R-SMAD) (By simila [...]
Fpr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065799Formyl peptide receptor 2; High affinity receptor for N-formyl-methionyl peptides (FMLP), which are powerful neutrophil chemotactic factors. Stimulates chemotaxis in immune cells to site of infec [...]
Rtn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065810Reticulon-3; May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. [...]
Thoc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065819THO complex subunit 7 homolog; Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, proc [...]
Rgs17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065825Regulator of G-protein signaling 17; Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2 (By simila [...]
Cdkn1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000065832Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SP [...]
Nup188 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065836Nucleoporin NUP188 homolog; May function as a component of the nuclear pore complex (NPC).
Cggbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065845CGG triplet repeat-binding protein 1; Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter (By similarity).
Zfp580 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065861Zinc finger protein 580; Involved in the regulation of endothelial cell proliferation and migration. Mediates H(2)O(2)-induced leukocyte chemotaxis by elevating interleukin-8 production and may p [...]
Sdc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065877Syndecan-3; Cell surface proteoglycan that may bear heparan sulfate. May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from t [...]
Krt72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065922Keratin, type II cytoskeletal 72; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (By similarity).
Slc20a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065935Sodium-dependent phosphate transporter 2; Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for [...]
Hmgb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065940High mobility group protein B2; Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associa [...]
Amelx protein networkhttps://string-db.org/network/10090.ENSMUSP00000065966Amelogenin, X isoform; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a ma [...]
Mapk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065983Mitogen-activated protein kinase 1; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which pla [...]
Ddx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000065987ATP-dependent RNA helicase DDX1; Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. Possesses AT [...]
Maneal protein networkhttps://string-db.org/network/10090.ENSMUSP00000066000Glycoprotein endo-alpha-1,2-mannosidase-like protein.
Cdh24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066005Cadherin-24; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the [...]
Lrrc8c protein networkhttps://string-db.org/network/10090.ENSMUSP00000066015Volume-regulated anion channel subunit LRRC8C; Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cel [...]
Socs4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066031Suppressor of cytokine signaling 4; SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate- recognition component of a SCF-l [...]
Anxa7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066035Annexin A7; Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis; Belongs to the annexin family.
Eif3k protein networkhttps://string-db.org/network/10090.ENSMUSP00000066038Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein [...]
Alas2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000660405-aminolevulinate synthase, erythroid-specific, mitochondrial.
Epm2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000066050Laforin; Plays an important role in preventing glycogen hyperphosphorylation and the formation of insoluble aggregates, via its activity as glycogen phosphatase, and by promoting the ubiquitinati [...]
Actn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066068Alpha-actinin-4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking vi [...]
Ech1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066092Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA; Belongs to the enoyl-CoA hydratase/isomerase family.
Slc39a14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066108Zinc transporter ZIP14; Broad-scope metal ion transporter with a preference for zinc uptake. Also mediates cellular uptake of nontransferrin-bound iron.
Rnf181 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066128E3 ubiquitin-protein ligase RNF181; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquiti [...]
Smagp protein networkhttps://string-db.org/network/10090.ENSMUSP00000066137Small cell adhesion glycoprotein; May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation (By similarity).
Ubap2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000066138Ubiquitin-associated protein 2-like; Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs).
Xlr4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000066171X-linked lymphocyte regulated gene 4.
Immt protein networkhttps://string-db.org/network/10090.ENSMUSP00000066181MICOS complex subunit Mic60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner mem [...]
Elob protein networkhttps://string-db.org/network/10090.ENSMUSP00000066210Elongin-B; SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A [...]
Spink5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066214Serine peptidase inhibitor, Kazal type 5.
Cib4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066222Calcium and integrin-binding family member 4.
Smco3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066235Single-pass membrane and coiled-coil domain-containing protein 3.
Rap1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000066238Ras-related protein Rap-1b; GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct [...]
Ticam2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066239TIR domain-containing adapter molecule 2; Functions as sorting adapter in different signaling pathways to facilitate downstream signaling leading to type I interferon induction. In TLR4 signaling [...]
Eya2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066244Eyes absent homolog 2; Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Ty [...]
Ercc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066256DNA excision repair protein ERCC-6; Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the tr [...]
Scrt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066280Transcriptional repressor scratch 2; May be involved in transcriptional regulation; Belongs to the snail C2H2-type zinc-finger protein family.
Nlgn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066304Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and pro [...]
Rbm12b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066311RNA-binding protein 12B-B.
Ppp4r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066314Serine/threonine-protein phosphatase 4 regulatory subunit 2; Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule orga [...]
Rnf103 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066324E3 ubiquitin-protein ligase RNF103; Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway.
Rab3gap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066325Rab3 GTPase-activating protein non-catalytic subunit; Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are [...]
Chrna4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066338Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-con [...]
Magea8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066341Melanoma antigen, family A, 8.
Fam49b protein networkhttps://string-db.org/network/10090.ENSMUSP00000066359Protein FAM49B.
A930004D18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000066378RIKEN cDNA A930004D18 gene.
Galr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066381Galanin receptor type 1; Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity; Belongs to the G-protein coupled recept [...]
Prr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066396Proline-rich protein 5; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be [...]
Sp100 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066399Nuclear autoantigen Sp-100; Together with PML, this tumor suppressor is a major constituent of the PML bodies, a subnuclear organelle involved in a large number of physiological processes includi [...]
Lonrf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066403LON peptidase N-terminal domain and RING finger protein 1.
Setd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066413Actin-histidine N-methyltransferase; Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscl [...]
Pfkfb2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000664266-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; Synthesis and degradation of fructose 2,6-bisphosphate.
Cldn17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066427Claudin-17; Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tub [...]
Mllt11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066448Protein AF1q; Cofactor for the transcription factor TCF7. Involved in regulation of lymphoid development by driving multipotent hematopoietic progenitor cells towards a T-cell fate; Belongs to th [...]
Gpr21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066449Probable G-protein coupled receptor 21; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Lgals4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066461Galectin-4; Galectin that binds lactose and a related range of sugars.
Defb40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066465Beta-defensin 40; Has antibacterial activity.
Lce3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000066468Late cornified envelope 3A.
Agt protein networkhttps://string-db.org/network/10090.ENSMUSP00000066488Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone r [...]
Nup214 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066492Nuclear pore complex protein Nup214; Has a critical role in nucleocytoplasmic transport (By similarity). May serve as a docking site in the receptor-mediated import of substrates across the nucle [...]
Mrpl35 protein networkhttps://string-db.org/network/10090.ENSMUSP0000006649339S ribosomal protein L35, mitochondrial.
Zscan4d protein networkhttps://string-db.org/network/10090.ENSMUSP00000066504Zinc finger and SCAN domain containing protein 4D; Transcription factor required to regulate early development. Binds telomeres and plays a key role in genomic stability by regulating telomere el [...]
B4galt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066515Beta-1,4-galactosyltransferase 6; Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point [...]
Khdrbs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066516KH domain-containing, RNA-binding, signal transduction-associated protein 1; Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptor [...]
Abhd16b protein networkhttps://string-db.org/network/10090.ENSMUSP00000066520Protein ABHD16B; Belongs to the AB hydrolase superfamily. ABHD16 family.
Lipg protein networkhttps://string-db.org/network/10090.ENSMUSP00000066536Endothelial lipase; Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin (By similarity).
Gabre protein networkhttps://string-db.org/network/10090.ENSMUSP00000066543Gamma-aminobutyric acid (GABA) A receptor, subunit epsilon; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
Plekha2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066546Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins t [...]
Epha3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066554Ephrin type-A receptor 3; Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling [...]
Soga1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066556C-terminal 80 kDa form; Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner. Belongs to the SOGA family.
Ppm1h protein networkhttps://string-db.org/network/10090.ENSMUSP00000066561Protein phosphatase 1H; Dephosphorylates CDKN1B at 'Thr-187', thus removing a signal for proteasomal degradation.
B3gat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066582Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins; Belongs to the glycosyltr [...]
Phtf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066607Putative homeodomain transcription factor 1; May play a role in transcription regulation.
Rgs7bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000066614Regulator of G-protein signaling 7-binding protein; Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellula [...]
Per2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066620Period circadian protein homolog 2; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiolo [...]
Glrx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066621Glutaredoxin-3; Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins (By similarity) [...]
Ago3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066633Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Propos [...]
Rnase9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066637Inactive ribonuclease-like protein 9; Does not exhibit any ribonuclease activity; Belongs to the pancreatic ribonuclease family.
Pabpc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066639Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
Trim50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066662E3 ubiquitin-protein ligase TRIM50; E3 ubiquitin-protein ligase that ubiquitinates Beclin-1/BECN1 in a 'Lys-63'-dependent manner enhancing its binding to ULK1. In turn, promotes starvation-induce [...]
Chek2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066679Serine/threonine-protein kinase Chk2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presen [...]
Nkx2-4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066690Homeobox protein Nkx-2.4; Probable transcription factor; Belongs to the NK-2 homeobox family.
Nab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066696NGFI-A-binding protein 1; Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2.
Mpz protein networkhttps://string-db.org/network/10090.ENSMUSP00000066701Myelin protein P0; Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compa [...]
Smim10l2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000066705Protein Smim10l2a.
Marc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066715Mitochondrial amidoxime reducing component 2; Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycle [...]
Epha6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066734Ephrin type-A receptor 6; Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling [...]
Ppp6r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066736Serine/threonine-protein phosphatase 6 regulatory subunit 1; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphory [...]
Npr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066737Atrial natriuretic peptide receptor 3; Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and [...]
Lrrc15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066777Leucine-rich repeat-containing protein 15.
Slc6a13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066779Sodium- and chloride-dependent GABA transporter 2; Sodium-dependent GABA and taurine transporter. In presynaptic terminals, regulates GABA signaling termination through GABA uptake. In the liver, [...]
Tex37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066786Testis-expressed sequence 37 protein.
Ep300 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066789Histone acetyltransferase p300; Functions as histone acetyltransferase and regulates transcription via chromatin remodeling (By similarity). Acetylates all four core histones in nucleosomes (By s [...]
Rsrc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066797Serine/Arginine-related protein 53; Plays a role in pre-mRNA splicing. Involved in both constitutive and alternative pre-mRNA splicing. May have a role in the recognition of the 3' splice site du [...]
Ddx19b protein networkhttps://string-db.org/network/10090.ENSMUSP00000066806DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b.
Zmat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066815Zinc finger matrin-type protein 1.
Penk protein networkhttps://string-db.org/network/10090.ENSMUSP00000066822Met-enkephalin-Arg-Ser-Leu; Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and respo [...]
Nlrp4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000066841NACHT, LRR and PYD domains-containing protein 4A; May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound rec [...]
Slit3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066857Slit homolog 3 protein; May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.
Isoc2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000066859Isochorismatase domain-containing protein 2B.
Hspa12a protein networkhttps://string-db.org/network/10090.ENSMUSP00000066860Heat shock 70 kDa protein 12A; Adapter protein for SORL1, but not SORT1. Delays SORL1 internalization and affects SORL1 subcellular localization. Belongs to the heat shock protein 70 family.
Cdh22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066864Cadherin-22; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the [...]
Foxd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066868Forkhead box protein D2; Probable transcription factor involved in embryogenesis and somatogenesis.
Cadm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066880Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity.
Lnpk protein networkhttps://string-db.org/network/10090.ENSMUSP00000066891Endoplasmic reticulum junction formation protein lunapark; Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology. Involved in the stabilization of nas [...]
Ngef protein networkhttps://string-db.org/network/10090.ENSMUSP00000066894Ephexin-1; Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone [...]
Sult2a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066897Sulfotransferase; Belongs to the sulfotransferase 1 family.
Rnf133 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066906E3 ubiquitin-protein ligase RNF133; Has E3 ubiquitin-protein ligase activity.
Amacr protein networkhttps://string-db.org/network/10090.ENSMUSP00000066915Alpha-methylacyl-CoA racemase; Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters (By similarity). Acts only on coenzyme A thioesters [...]
Gpr141 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066921Probable G-protein coupled receptor 141; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Gata4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066927Transcription factor GATA-4; Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development (By similarity). In cooperation with TBX5, it [...]
Ms4a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066960Membrane-spanning 4-domains, subfamily A, member 5.
Klk15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066969Kallikrein-related-peptidase 15; Belongs to the peptidase S1 family.
Olfr378 protein networkhttps://string-db.org/network/10090.ENSMUSP00000066971Olfactory receptor.
Rad54b protein networkhttps://string-db.org/network/10090.ENSMUSP00000066977DNA repair and recombination protein RAD54B; Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epista [...]
Mrps21 protein networkhttps://string-db.org/network/10090.ENSMUSP0000006699028S ribosomal protein S21, mitochondrial; Belongs to the bacterial ribosomal protein bS21 family.
Pld4 protein networkhttps://string-db.org/network/10090.ENSMUSP000000670025'-3' exonuclease PLD4; 5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentra [...]
Ang5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067008Angiogenin-3; May promote vascularization of normal and malignant tissues (By similarity). Has low ribonuclease activity (in vitro).
Rhob protein networkhttps://string-db.org/network/10090.ENSMUSP00000067013Rho-related GTP-binding protein RhoB; Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling [...]
Adamts15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067022A disintegrin and metalloproteinase with thrombospondin motifs 15.
Ston1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067027Stonin-1; May be involved in the endocytic machinery.
Ankrd33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067028Photoreceptor ankyrin repeat protein; [Isoform 1]: Acts as a transcriptional repressor for CRX- activated photoreceptor gene regulation.
Gm5142 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067031Predicted gene, EG380907.
Plpp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067035Phospholipid phosphatase 5; Magnesium-independent phospholipid phosphatase with broad substrate specificity. Preferentially catalyzes the conversion of diacylglycerol pyrophosphate into phosphati [...]
Lep protein networkhttps://string-db.org/network/10090.ENSMUSP00000067046Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, whic [...]
Zfp438 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067049Zinc finger protein 438.
Rnf185 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067053E3 ubiquitin-protein ligase RNF185; E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1. Acts in the endoplasmic [...]
Adcyap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067057Pituitary adenylate cyclase-activating polypeptide 27; Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells (By similarity). Promotes neuron projection [...]
Lif protein networkhttps://string-db.org/network/10090.ENSMUSP00000067066Leukemia inhibitory factor; LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid [...]
Tas2r107 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067082Taste receptor type 2 member 107; Putative taste receptor which may play a role in the perception of bitterness.
Irs4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067085Insulin receptor substrate 4; Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity, such as insulin receptor, IGF1R and FGFR1, and a complex network o [...]
Daw1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067102Dynein assembly factor with WDR repeat domains 1.
Usp45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067109Ubiquitin carboxyl-terminal hydrolase 45; May be involved in the maintenance of photoreceptor function. Belongs to the peptidase C19 family.
Slc22a28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067114Solute carrier family 22, member 28.
Spink2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067117Serine protease inhibitor Kazal-type 2; As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thu [...]
Mrfap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067135MORF4 family-associated protein 1; Belongs to the MORF4 family-associated protein family.
Aatk protein networkhttps://string-db.org/network/10090.ENSMUSP00000067181Serine/threonine-protein kinase LMTK1; May be involved in neuronal differentiation; Belongs to the protein kinase superfamily. Tyr protein kinase family.
Rhox2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000067190Reproductive homeobox on X chromosome 2.
Defb37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067193Beta-defensin 37; Has antibacterial activity.
Zfp365 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067197Protein ZNF365; Contributes to genomic stability by preventing telomere dysfunction. Involved in the morphogenesis of basket cells in the somatosensory cortex during embryogenesis. Involved in th [...]
Snupn protein networkhttps://string-db.org/network/10090.ENSMUSP00000067200Snurportin-1; Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-ca [...]
Cdc42ep3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067217Cdc42 effector protein 3; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pse [...]
Nav1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067241Neuron navigator 1; May be involved in neuronal migration. Belongs to the Nav/unc-53 family.
Acvr2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000067305Activin receptor type-2A; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate [...]
A430033K04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000067316RIKEN cDNA A430033K04 gene.
Terb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067324Telomere repeats-binding bouquet formation protein 1; Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homolo [...]
Rspo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067325R-spondin-2; Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 an [...]
Zfp217 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067334Zinc finger protein 217.
Supt7l protein networkhttps://string-db.org/network/10090.ENSMUSP00000067337STAGA complex 65 subunit gamma.
Clk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067341Dual specificity protein kinase CLK3; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the sp [...]
Rnf222 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067364RING finger protein 222.
Nanos3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067385Nanos homolog 3; Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell pro [...]
Ang protein networkhttps://string-db.org/network/10090.ENSMUSP00000067434Angiogenin; Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing [...]
Stfa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067445Stefin-3; This is an intracellular thiol proteinase inhibitor; Belongs to the cystatin family.
Arhgap4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067477Rho GTPase-activating protein p115 splice form 1.
Siah2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067496E3 ubiquitin-protein ligase SIAH2; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from a [...]
Tmem248 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067501Transmembrane protein 248.
Swt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067516Transcriptional protein SWT1.
Zbtb48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067521Telomere zinc finger-associated protein; Telomere-binding protein that acts as a regulator of telomere length. Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. Preferentially bin [...]
Slamf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067527SLAM family member 8; May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
Ostn protein networkhttps://string-db.org/network/10090.ENSMUSP00000067539Processed Osteocrin; Hormone that acts as a ligand for natriuretic peptide receptor NPR3/NPR-C and promotes bone growth and physical endurance in muscle. Acts as a regulator of osteoblast differe [...]
C8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000067541Complement component C8 alpha chain; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of t [...]
Srr protein networkhttps://string-db.org/network/10090.ENSMUSP00000067552Serine racemase; Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
Defb38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067553Beta-defensin 38; Synthetic Defb38 kills both Gram-negative (E.coli and P.aeruginosa) and Gram-positive (E.faecium) bacteria.
Fat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067556Protocadherin Fat 2; Involved in the regulation of cell migration (By similarity). May be involved in mediating the organization of the parallel fibers of granule cells during cerebellar developm [...]
Rcl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067579RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 tha [...]
Sh3bp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067581SH3 domain-binding protein 4; May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act [...]
Dgkk protein networkhttps://string-db.org/network/10090.ENSMUSP00000067591Diacylglycerol kinase.
Gykl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067598Glycerol kinase-like 1; Belongs to the FGGY kinase family.
Lcor protein networkhttps://string-db.org/network/10090.ENSMUSP00000067603Ligand-dependent corepressor; Repressor of ligand-dependent transcription activation by various nuclear repressors. Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PG [...]
Slc25a40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067611Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family.
Ptpn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067614Tyrosine-protein phosphatase non-receptor type 4; Phosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis. Regulates neuronal cell homeostasis by protecting n [...]
Gabrg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067632Gamma-aminobutyric acid receptor subunit gamma-3; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor [...]
Tas2r129 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067640Taste receptor type 2 member 129; Putative taste receptor which may play a role in the perception of bitterness.
Stpg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067647O(6)-methylguanine-induced apoptosis 2; May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine.
Rdh8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067662Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Klf13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067680Krueppel-like factor 13; Transcription factor that activates expression from GC-rich minimal promoter regions, including genes in the cells of the erythroid lineage.
Sec61b protein networkhttps://string-db.org/network/10090.ENSMUSP00000067681Protein transport protein Sec61 subunit beta; Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic [...]
Dgcr6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067682Protein DGCR6; May have a role in early embryogenesis; Belongs to the gonadal family.
Iqgap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067685Ras GTPase-activating-like protein IQGAP2; Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.
Ano9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067689Anoctamin-9; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide. Does not exhibit calcium- activated chloride channel [...]
Obox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067691Oocyte-specific homeobox 1.
Rarb protein networkhttps://string-db.org/network/10090.ENSMUSP00000067694Retinoic acid receptor beta; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic a [...]
Thsd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067701Thrombospondin type-1 domain-containing protein 1.
Actn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067708Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity).
Serpinb9d protein networkhttps://string-db.org/network/10090.ENSMUSP00000067710Serine (Or cysteine) peptidase inhibitor, clade B, member 9D; Belongs to the serpin family.
Pcdhga8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067728Protocadherin gamma subfamily A, 8.
Tas2r144 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067734Taste receptor type 2 member 40; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calci [...]
Ldb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067737LIM domain-binding protein 2; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors.
Hook2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067752Protein Hook homolog 2; Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting [...]
Cpne8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067774Copine-8; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.
Afap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067779Actin filament-associated protein 1; Can cross-link actin filaments into both network and bundle structures. May modulate changes in actin filament integrity and induce lamellipodia formation. Ma [...]
Fzd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067783Frizzled-5; Receptor for Wnt proteins. Can activate WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 (in vitro); the in vivo situation may be different since not all of these are known to be coexpresse [...]
Sos1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067786Son of sevenless homolog 1; Promotes the exchange of Ras-bound GDP by GTP. Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (By similarity). [...]
Lysmd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067811LysM and putative peptidoglycan-binding domain-containing protein 1.
Dglucy protein networkhttps://string-db.org/network/10090.ENSMUSP00000067830D-glutamate cyclase, mitochondrial; D-glutamate cyclase that converts D-glutamate to 5-oxo-D- proline.
Bpi protein networkhttps://string-db.org/network/10090.ENSMUSP00000067837Bactericidal permeability-increasing protein; The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very [...]
Tfg protein networkhttps://string-db.org/network/10090.ENSMUSP00000067867Trk-fused protein.
Btla protein networkhttps://string-db.org/network/10090.ENSMUSP00000067877B- and T-lymphocyte attenuator; Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. May interact in cis (on the same cell) or [...]
Tbcel protein networkhttps://string-db.org/network/10090.ENSMUSP00000067882Tubulin-specific chaperone cofactor E-like protein; Acts as a regulator of tubulin stability.
Rxfp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067897Relaxin receptor 2; Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for L [...]
Wls protein networkhttps://string-db.org/network/10090.ENSMUSP00000067898Protein wntless homolog; Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular [...]
Aarsd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067912Alanyl-tRNA editing protein Aarsd1; Functions in trans to edit the amino acid moiety from incorrectly charged Ser-tRNA(Ala); Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfa [...]
Srsf12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067939Serine/arginine-rich splicing factor 12; Splicing factor that seems to antagonize SR proteins in pre- mRNA splicing regulation.
Gpsm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000067964G-protein-signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha sub [...]
Eef2kmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000068003Protein-lysine N-methyltransferase EEF2KMT; Catalyzes the trimethylation of eukaryotic elongation factor 2 (EEF2) on 'Lys-525'; Belongs to the class I-like SAM-binding methyltransferase superfami [...]
Tmem179 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068004Transmembrane protein 179.
Hunk protein networkhttps://string-db.org/network/10090.ENSMUSP00000068007Hormonally up-regulated neu tumor-associated kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Xlr protein networkhttps://string-db.org/network/10090.ENSMUSP00000068044X-linked lymphocyte-regulated protein PM1.
Klhdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068046Kelch domain-containing protein 1.
Dmp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068053Dentin matrix acidic phosphoprotein 1; May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional [...]
Bsx protein networkhttps://string-db.org/network/10090.ENSMUSP00000068057Brain-specific homeobox protein homolog; DNA binding protein that function as transcriptional activator. Is essential for normal postnatal growth and nursing. Is an essential factor for neuronal [...]
Bhlhb9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068067Protein BHLHb9; May play a role in the control of cellular aging and survival; Belongs to the GPRASP family.
Ldhd protein networkhttps://string-db.org/network/10090.ENSMUSP00000068086Probable D-lactate dehydrogenase, mitochondrial; Involved in D-lactate, but not L-lactate catabolic process. Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
Utp18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068103U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.
Fam72a protein networkhttps://string-db.org/network/10090.ENSMUSP00000068111Protein FAM72A; May play a role in the regulation of cellular reactive oxygen species metabolism. May participate in cell growth regulation (By similarity); Belongs to the FAM72 family.
Ghrhr protein networkhttps://string-db.org/network/10090.ENSMUSP00000068120Growth hormone-releasing hormone receptor; Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growt [...]
Cd8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000068123T-cell surface glycoprotein CD8 alpha chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external an [...]
Cpsf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068148Cleavage and polyadenylation specificity factor subunit 3; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recog [...]
Gtsf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068158Gametocyte-specific factor 2.
Impa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068174Inositol monophosphatase 1; Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological targe [...]
Rims3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068178Regulating synaptic membrane exocytosis protein 3; Regulates synaptic membrane exocytosis.
Sertad3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068187SERTA domain-containing protein 3; Strong transcriptional coactivator.
Zfp608 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068192Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription.
Rab31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068195Ras-related protein Rab-31; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle bet [...]
Zmym3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068197Zinc finger MYM-type protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization.
Dcbld1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068203Discoidin, CUB and LCCL domain-containing protein 1.
1700001K19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000068238RIKEN cDNA 1700001K19 gene.
Gucy2g protein networkhttps://string-db.org/network/10090.ENSMUSP00000068253Guanylate cyclase 2G; Probably plays a specific functional role in the testis by binding to yet not identified ligand.
Bcl11b protein networkhttps://string-db.org/network/10090.ENSMUSP00000068258B-cell lymphoma/leukemia 11B; Key regulator of both differentiation and survival of T- lymphocytes during thymocyte development in mammals. Essential in controlling the responsiveness of hematopo [...]
Strap protein networkhttps://string-db.org/network/10090.ENSMUSP00000068267Serine-threonine kinase receptor-associated protein; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Th [...]
Thra protein networkhttps://string-db.org/network/10090.ENSMUSP00000068281Thyroid hormone receptor alpha; Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thy [...]
Ugt2b5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068282UDP-glucuronosyltransferase 2B17; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
Agtr1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000068298Type-1B angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to [...]
Trmt1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000068309TRMT1-like protein; May play a role in motor coordination and exploratory behavior; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Nadk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068318NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor (By similarity).
Kbtbd11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068321Kelch repeat and BTB domain-containing protein 11.
Tas2r102 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068332Taste receptor type 2 member 102; Putative taste receptor which may play a role in the perception of bitterness.
Map1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000068374Microtubule-associated protein 1B; Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the [...]
Fto protein networkhttps://string-db.org/network/10090.ENSMUSP00000068380Alpha-ketoglutarate-dependent dioxygenase FTO; RNA demethylase that mediates oxidative demethylation of different RNA species, such as mRNAs, tRNAs and snRNAs, and acts as a regulator of fat mass [...]
C1ql4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068402Complement C1q-like protein 4; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. May inhibit adipocyte differentiation a [...]
Alg13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068403Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13; [Isoform 1]: Possible multifunctional enzyme with both glycosyltransferase and deubiquitinase activities.
Aym1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068426Activator of yeast meiotic promoters 1.
Atg4d protein networkhttps://string-db.org/network/10090.ENSMUSP00000068450Cysteine protease ATG4D, mitochondrial; [Cysteine protease ATG4D]: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C- terminal amino acid of ATG [...]
Itgam protein networkhttps://string-db.org/network/10090.ENSMUSP00000068468Integrin alpha-M; Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles [...]
Prr9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068470Proline-rich protein 9.
Ldlrad4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068471Low-density lipoprotein receptor class A domain-containing protein 4; Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiat [...]
Ak1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068479Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also possesses broad nucleoside diphosphate kinase activity. Plays an importan [...]
Tgoln1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068487Trans-Golgi network integral membrane protein 1; May be involved in regulating membrane traffic to and from trans-Golgi network.
Dph3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068491DPH3 homolog; Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2; Belongs to the DPH3 family.
Serp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068508Stress-associated endoplasmic reticulum protein 2; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against [...]
Tsr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068511Ribosome biogenesis protein TSR3 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis.
Mapkbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068516Mitogen-activated protein kinase-binding protein 1; Negative regulator of NOD2 function. It down-regulates NOD2- induced processes such as activation of NF-kappa-B signaling, IL8 secretion and an [...]
B4galt7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068532Beta-1,4-galactosyltransferase 7; Required for the biosynthesis of the tetrasaccharide linkage region of proteoglycans, especially for small proteoglycans in skin fibroblasts; Belongs to the glyc [...]
Ccser2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068550Serine-rich coiled-coil domain-containing protein 2; Microtubule-binding protein which might play a role in microtubule bundling; Belongs to the CCSER family.
Tmem120b protein networkhttps://string-db.org/network/10090.ENSMUSP00000068551Transmembrane protein 120B; Necessary for efficient adipogenesis. Belongs to the TMEM120 family.
Adnp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068560Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Retsat protein networkhttps://string-db.org/network/10090.ENSMUSP00000068568All-trans-retinol 13,14-reductase; Catalyzes the saturation of all-trans-retinol to all-trans- 13,14-dihydroretinol. Does not exhibit any activity toward all-trans- retinoic acid, nor 9-cis, 11-c [...]
Strip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068587Striatin-interacting protein 1; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape (By similarity); B [...]
B3gntl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068590UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1; Putative glycosyltransferase; Belongs to the glycosyltransferase 2 family.
Tmem175 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068607Endosomal/lysosomal potassium channel TMEM175; Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak [...]
Emc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068610ER membrane protein complex subunit 7; Belongs to the EMC7 family.
Ccdc88c protein networkhttps://string-db.org/network/10090.ENSMUSP00000068629Protein Daple; Required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Binds to ligand-activated Wnt receptor FZD7, displacing DVL1 from th [...]
Osbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068652Oxysterol-binding protein 2; Binds 7-ketocholesterol; Belongs to the OSBP family.
Mdm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068661Protein Mdm4; Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted de [...]
Zcchc24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068677Zinc finger CCHC domain-containing protein 24.
Lclat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068690Lysocardiolipin acyltransferase 1; Exhibits acyl-CoA:lysocardiolipin acyltransferase (ALCAT) activity; catalyzes the reacylation of lyso-cardiolipin to cardiolipin (CL), a key step in CL remodeli [...]
Pla2g3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068699Phospholipase A2, group III.
Nusap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068713Nucleolar and spindle-associated protein 1; Microtubule-associated protein with the capacity to bundle and stabilize microtubules. May associate with chromosomes and promote the organization of m [...]
Vps13a protein networkhttps://string-db.org/network/10090.ENSMUSP00000068716Vacuolar protein sorting-associated protein 13A; May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane.
Rgs14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068731Regulator of G-protein signaling 14; Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby d [...]
Dnah7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000068738Dynein, axonemal, heavy chain 7B.
AV320801 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068753Expressed sequence AV320801.
Dnah6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068758Dynein, axonemal, heavy chain 6.
4931417E11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000068770RIKEN cDNA 4931417E11 gene.
Cebpzos protein networkhttps://string-db.org/network/10090.ENSMUSP00000068772Protein CEBPZOS.
Zzef1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068790Zinc finger ZZ-type and EF-hand domain-containing protein 1.
Khdc1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000068792KH homology domain-containing protein 1C; Belongs to the KHDC1 family.
Cspp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068804Centrosome and spindle pole associated protein 1; May play a role in cell-cycle-dependent microtubule organization.
Zfp248 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068807Zinc finger protein 248.
Pcdha1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068828Protocadherin alpha 1.
Trib1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068834Tribbles homolog 1; Adapter protein involved in protein degradation by interacting with COP1 ubiquitin ligase. Promotes CEBPA degradation and inhibits its function. Controls macrophage, eosinophi [...]
Pcdhgc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068846Protocadherin gamma subfamily C, 4.
Ptrh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068850Probable peptidyl-tRNA hydrolase.
Pfn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068890Profilin-2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By b [...]
Capn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068895Calpain-2 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteoly [...]
Top2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000068896DNA topoisomerase 2-alpha; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. Essential during mitos [...]
Mok protein networkhttps://string-db.org/network/10090.ENSMUSP00000068904MAPK/MAK/MRK overlapping kinase; Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent [...]
Cebpe protein networkhttps://string-db.org/network/10090.ENSMUSP00000068927CCAAT/enhancer-binding protein epsilon; Transcriptional activator. C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced [...]
Mta3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068931Metastasis-associated protein MTA3; Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and [...]
D630039A03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000068932RIKEN cDNA D630039A03 gene.
Fpgt protein networkhttps://string-db.org/network/10090.ENSMUSP00000068939Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L-fucose arising from the turnover [...]
Abcd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068940ATP-binding cassette sub-family D member 2; Probable transporter.
Nkg7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068946Protein NKG7.
Serpinc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068971Antithrombin-III; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and X [...]
Ccdc172 protein networkhttps://string-db.org/network/10090.ENSMUSP00000068972Coiled-coil domain-containing protein 172.
Usp17la protein networkhttps://string-db.org/network/10090.ENSMUSP00000068997Ubiquitin carboxyl-terminal hydrolase 17-like protein A; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Has deubiquitin [...]
Rps15 protein networkhttps://string-db.org/network/10090.ENSMUSP0000006900440S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
Pde5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000069011cGMP-specific 3',5'-cyclic phosphodiesterase; Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specifi [...]
Fank1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069013Fibronectin type 3 and ankyrin repeat domains 1 protein; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis.
Prr18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069019Proline-rich protein 18.
Sema5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000069024Semaphorin-5A; Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory e [...]
Gbp10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069042Guanylate-binding protein 10.
Capn12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069055Calpain-12; Calcium-regulated non-lysosomal thiol-protease.
Klhl26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069077Kelch-like protein 26.
Commd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069078COMM domain-containing protein 4; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Down-regulates activation of NF-kappa-B.
Casr protein networkhttps://string-db.org/network/10090.ENSMUSP00000069080Extracellular calcium-sensing receptor; G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis ( [...]
Gnpda1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069081Glucosamine-6-phosphate isomerase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the emb [...]
Mill1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069083MHC I-like leukocyte 1; Belongs to the MHC class I family.
Lamb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069087Laminin subunit beta-2; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development [...]
Fam122b protein networkhttps://string-db.org/network/10090.ENSMUSP00000069112Protein FAM122B.
Ackr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069114Atypical chemokine receptor 3; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal [...]
Babam2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069133BRISC and BRCA1-A complex member 2; Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to t [...]
Commd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069159COMM domain-containing protein 5; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase tra [...]
Tmem158 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069161Transmembrane protein 158; Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide; Belongs to the TMEM158 family.
9330182L06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000069165UPF0577 protein KIAA1324-like homolog; Belongs to the UPF0577 family.
Pard6g protein networkhttps://string-db.org/network/10090.ENSMUSP00000069182Partitioning defective 6 homolog gamma; Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The [...]
Gja6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069187Gap junction alpha-6 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a [...]
Ephx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069209Bifunctional epoxide hydrolase 2; Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobi [...]
Inka2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069212PAK4-inhibitor INKA2; Inhibitor of the serine/threonine-protein kinase PAK4. Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity.
3110082I17Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000069230Uncharacterized protein C7orf50 homolog.
Tnfaip6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069231Tumor necrosis factor-inducible gene 6 protein; Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.
Cers3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069238Ceramide synthase 3; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very- long (C22:0-C24:0) and ultra long chain (m [...]
Rsbn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069246Lysine-specific demethylase 9; Histone demethylase that specifically demethylates dimethylated 'Lys-20' of histone H4 (H4K20me2), thereby modulating chromosome architecture; Belongs to the round [...]
Spink6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069247Serine protease inhibitor Kazal-type 6; Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK5 and human KLK2, KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhi [...]
Smpd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069255Sphingomyelin phosphodiesterase 3; Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arres [...]
Ppp1r12a protein networkhttps://string-db.org/network/10090.ENSMUSP00000069257Protein phosphatase 1 regulatory subunit 12A; Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Cap [...]
Pias3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069259E3 SUMO-protein ligase PIAS3; Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Pla [...]
Zfp618 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069275Zinc finger protein 618; May be involved in transcriptional regulation.
Pi4k2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000069284Phosphatidylinositol 4-kinase type 2-alpha; Membrane-bound phosphatidylinositol-4 kinase (PI4-kinase) that catalyzes the phosphorylation of phosphatidylinositol (PI) to phosphatidylinositol 4-pho [...]
Tas2r109 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069300Taste receptor type 2 member 109; Putative taste receptor which may play a role in the perception of bitterness.
Cpn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069318Carboxypeptidase N subunit 2; The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric mod [...]
Ly9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069319T-lymphocyte surface antigen Ly-9; Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are [...]
Pld5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069326Inactive phospholipase D5; Belongs to the phospholipase D family.
Madd protein networkhttps://string-db.org/network/10090.ENSMUSP00000069350MAP kinase-activating death domain protein; Plays a significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Converts GDP- bound inactive form of R [...]
Nat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069359Arylamine N-acetyltransferase 3; Participates in the detoxification of a plethora of hydrazine and arylamine drugs.
Trim23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069371E3 ubiquitin-protein ligase TRIM23; Acts as an E3 ubiquitin-protein ligase. Plays an essential role in autophagy activation during viral infection. Mechanistically, activates TANK-binding kinase [...]
Itgb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069416Integrin beta-5; Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
C4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000069418Complement C4 alpha chain; Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and imm [...]
Nt5c1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000069422Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ische [...]
Syp protein networkhttps://string-db.org/network/10090.ENSMUSP00000069429Synaptophysin; Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane (By similarity). Involved in the regulation of [...]
Gcn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069432eIF-2-alpha kinase activator GCN1; Acts as a positive activator of the GCN2 protein kinase activity in response to amino acid starvation. Forms a complex with EIF2AK4/GCN2 on translating ribosome [...]
Wiz protein networkhttps://string-db.org/network/10090.ENSMUSP00000069443Protein Wiz; May link EHMT1 and EHMT2 histone methyltransferases to the CTBP corepressor machinery. May be involved in EHMT1-EHMT2 heterodimer formation and stabilization; Belongs to the krueppel [...]
Glcci1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069444Glucocorticoid-induced transcript 1 protein.
Timd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069456T-cell immunoglobulin and mucin domain-containing protein 4; Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotox [...]
Ghr protein networkhttps://string-db.org/network/10090.ENSMUSP00000069457Growth hormone-binding protein; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By s [...]
Adam11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069466Disintegrin and metalloproteinase domain-containing protein 11; Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein.
Atp6v1g2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069482V-type proton ATPase subunit G 2; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in e [...]
Ercc6l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069488DNA excision repair protein ERCC-6-like 2; May be involved in early DNA damage response.
Abcg5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069495ATP-binding cassette sub-family G member 5; ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role [...]
Nr1d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069505Nuclear receptor subfamily 1 group D member 1; Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex tr [...]
Tchh protein networkhttps://string-db.org/network/10090.ENSMUSP00000069525Trichohyalin.
Stx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069529Syntaxin-3; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family.
Cpt1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000069539Carnitine O-palmitoyltransferase 1, brain isoform; May play a role in lipid metabolic process. Belongs to the carnitine/choline acetyltransferase family.
Iqcj protein networkhttps://string-db.org/network/10090.ENSMUSP00000069544IQ domain-containing protein J.
Rock1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069549Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organizat [...]
Yap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069554Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway t [...]
D930048N14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000069562RIKEN cDNA D930048N14 gene.
Npm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069578Nucleoplasmin-3; Plays a role in the regulation of diverse cellular processes such as ribosome biogenesis, chromatin remodeling or protein chaperoning. Modulates the histone chaperone function an [...]
Egr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069616Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'- GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded t [...]
Dhrs9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069631Dehydrogenase/reductase SDR family member 9; 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha- tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstaned [...]
Acot11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069636Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoy [...]
Adamts8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069644A disintegrin and metalloproteinase with thrombospondin motifs 8; Has anti-angiogenic properties.
Vmn2r43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069647EC2-V2R pheromone receptor protein.
Tusc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069652Tumor suppressor candidate gene 1 protein homolog.
Nkx2-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069666Homeobox protein Nkx-2.2; Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas. May also be involved in specifying diencephalic neurome [...]
Klhdc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069669Kelch domain-containing protein 10; Participates in the oxidative stress-induced cell death through MAP3K5 activation. Inhibits PPP5C phosphatase activity on MAP3K5.
Plpp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069670Phospholipid phosphatase 2; Magnesium-independent phospholipid phosphatase that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatid [...]
Klhl18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069674Kelch-like protein 18; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis (By similarity). The BCR(KLHL18) E3 [...]
Fgf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069681Fibroblast growth factor 7; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth fa [...]
Them6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069692Protein THEM6.
5031410I06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000069697RIKEN cDNA 5031410I06 gene.
Cndp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069699Beta-Ala-His dipeptidase; Belongs to the peptidase M20A family.
Apobec4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069723Putative C->U-editing enzyme APOBEC-4; Putative C to U editing enzyme whose physiological substrate is not yet known.
Gsx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069728GS homeobox 1; Probable transcription factor that binds to the DNA sequence 5'-GC[TA][AC]ATTA[GA]-3'. Activates the transcription of the GHRH gene. Plays an important role in pituitary developmen [...]
Rara protein networkhttps://string-db.org/network/10090.ENSMUSP00000069744Retinoic acid receptor alpha; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic [...]
Dnah5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069751Dynein heavy chain 5, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke [...]
Rras2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069752Ras-related protein R-Ras2; It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect th [...]
Tmem106c protein networkhttps://string-db.org/network/10090.ENSMUSP00000069764Transmembrane protein 106C.
Nanos2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069765Nanos homolog 2; Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis [...]
Tas2r117 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069768Taste receptor type 2 member 117; Putative taste receptor which may play a role in the perception of bitterness.
Mthfr protein networkhttps://string-db.org/network/10090.ENSMUSP00000069774Methylenetetrahydrofolate reductase; Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine.
9130008F23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000069779RIKEN cDNA 9130008F23 gene.
4933400A11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000069798F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subun [...]
Spag16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069821Sperm-associated antigen 16 protein; Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit STK36 to the cilium or apical surface of the cell to initiate [...]
Magea2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069832Melanoma antigen, family A, 2.
Prss58 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069833Putative inactive serine protease 58; Belongs to the peptidase S1 family.
Mipep protein networkhttps://string-db.org/network/10090.ENSMUSP00000069840Mitochondrial intermediate peptidase; Cleaves proteins, imported into the mitochondrion, to their mature size; Belongs to the peptidase M3 family.
Ppp1r36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069849Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
Cebpb protein networkhttps://string-db.org/network/10090.ENSMUSP00000069850CCAAT/enhancer-binding protein beta; Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Plays also a significant role in adipogenesis [...]
Itpkb protein networkhttps://string-db.org/network/10090.ENSMUSP00000069851Kinase; Belongs to the inositol phosphokinase (IPK) family.
Ydjc protein networkhttps://string-db.org/network/10090.ENSMUSP00000069864Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.
Mtnr1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000069872Melatonin receptor type 1A; High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis tox [...]
Krt7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069900Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells.
Rtl8c protein networkhttps://string-db.org/network/10090.ENSMUSP00000069901Retrotransposon Gag-like 8C.
A830005F24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000069912RIKEN cDNA A830005F24 gene.
Tgtp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069914T cell specific GTPase 1.
Mdfi protein networkhttps://string-db.org/network/10090.ENSMUSP00000069915MyoD family inhibitor; Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in th [...]
Cyp3a44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069932Cytochrome P450, family 3, subfamily a, polypeptide 44.
Rtl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069947Retrotransposon Gag-like protein 6.
Tmod2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069956Tropomodulin-2; Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in t [...]
Opa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000069965Optic atrophy 3 protein homolog; May play some role in mitochondrial processes; Belongs to the OPA3 family.
Uty protein networkhttps://string-db.org/network/10090.ENSMUSP00000070012Histone demethylase UTY; Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low KDM activity.
Cthrc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070018Collagen triple helix repeat-containing protein 1; May act as a negative regulator of collagen matrix deposition.
Prkcb protein networkhttps://string-db.org/network/10090.ENSMUSP00000070019Protein kinase C beta type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B [...]
Alkal2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070037ALK and LTK ligand 2; Ligand for receptor tyrosine kinases LTK and ALK. Stimulation of ALK signaling may be involved in regulation of cell proliferation and transformation; Belongs to the FAM150 [...]
Ndrg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070052Protein NDRG3; Belongs to the NDRG family.
Dand5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070057DAN domain family member 5; Seems to play a role in the correct specification of the left-right axis. May antagonize NODAL and BMP4 signaling. Cystine knot- containing proteins play important rol [...]
Zbtb26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070071Zinc finger and BTB domain-containing 26.
Gm14548 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070073Predicted gene 14548.
Ggcx protein networkhttps://string-db.org/network/10090.ENSMUSP00000070109Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversio [...]
Yy2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070112Transcription factor YY2; Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes. May antagonize YY1 and function in develop [...]
Nrgn protein networkhttps://string-db.org/network/10090.ENSMUSP00000070113NEUG(55-78); Regulates the affinity of calmodulin for calcium. Involved in synaptic plasticity and spatial learning. Belongs to the neurogranin family.
Xlr4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000070117X-linked lymphocyte-regulated 4C.
Doc2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000070119Double C2-like domain-containing protein alpha; Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium depende [...]
Nepn protein networkhttps://string-db.org/network/10090.ENSMUSP00000070130Nephrocan; May inhibit TGF-beta signaling.
Cd8b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070131T-cell surface glycoprotein CD8 beta chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and [...]
Tmem45a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070137Transmembrane protein 45A2.
9830107B12Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000070138RIKEN cDNA 9830107B12 gene.
Chchd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070149MICOS complex subunit Mic19; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner mem [...]
Gan protein networkhttps://string-db.org/network/10090.ENSMUSP00000070168Gigaxonin; Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein li [...]
B430305J03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000070175RIKEN cDNA B430305J03 gene.
Adra1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000070200Alpha-1B adrenergic receptor; This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect i [...]
Depp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070203Protein DEPP1; Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS.
Rpap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070209Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2; Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphoryl [...]
Zfp46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070216Zinc finger protein 436; May be involved in transcriptional regulation.
Gatad2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000070229Transcriptional repressor p66 alpha; Transcriptional repressor (By similarity). Enhances MBD2- mediated repression. Efficient repression requires the presence of GATAD2B (By similarity).
Retnlg protein networkhttps://string-db.org/network/10090.ENSMUSP00000070238Resistin-like gamma; Probable hormone (Probable). Promotes chemotaxis in myeloid cells ; Belongs to the resistin/FIZZ family.
Tg protein networkhttps://string-db.org/network/10090.ENSMUSP00000070239Thyroglobulin; Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) (By similarity). The synthesis of T3 and T4 involves iodination of sel [...]
Micu3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070241Calcium uptake protein 3, mitochondrial; May play a role in mitochondrial calcium uptake. Belongs to the MICU1 family. MICU3 subfamily.
Tas2r135 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070247Taste receptor type 2 member 135; Putative taste receptor which may play a role in the perception of bitterness.
Csnk1g3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070259Casein kinase I isoform gamma-3; Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It c [...]
B630019K06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000070261RIKEN cDNA B630019K06 gene.
Col8a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070270Collagen alpha-2(VIII) chain; Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the en [...]
Ddx55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070279ATP-dependent RNA helicase DDX55; Probable ATP-binding RNA helicase.
4933402N03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000070291RIKEN cDNA 4933402N03 gene.
Meig1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070310Meiosis-expressed gene 1 protein; Essential for spermiogenesis; Belongs to the MEIG1 family.
Cmbl protein networkhttps://string-db.org/network/10090.ENSMUSP00000070314Carboxymethylenebutenolidase homolog; Cysteine hydrolase; Belongs to the dienelactone hydrolase family.
Syt5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070322Synaptotagmin-5; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of ves [...]
Jmy protein networkhttps://string-db.org/network/10090.ENSMUSP00000070339Junction-mediating and -regulatory protein; Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that inc [...]
Bckdk protein networkhttps://string-db.org/network/10090.ENSMUSP00000070345[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regul [...]
Cdk17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070355Cyclin-dependent kinase 17; May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity).
Amy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070368Alpha-amylase 1.
Tmem171 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070369Transmembrane protein 171.
Togaram1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070382TOG array regulator of axonemal microtubules protein 1; Required for normal structure and function of primary cilia. Plays a role in the organization of axoneme microtubule bundles in primary cil [...]
Hs6st3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070394Heparan-sulfate 6-O-sulfotransferase 3; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine resi [...]
Tmem143 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070405Transmembrane protein 143.
Dnaja4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070413DnaJ homolog subfamily A member 4.
St3gal5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070414Lactosylceramide alpha-2,3-sialyltransferase; Catalyzes the formation of ganglioside GM3 (alpha-N- acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D-glucosylceramide), which is a precursor for m [...]
Grk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070445Beta-adrenergic receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.
Zfp37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070463Zinc finger protein 37; May have a role in regulating spermiogenesis.
Tagap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070466T-cell activation GTPase-activating protein 1.
Tbc1d30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070488TBC1 domain family member 30; GTPase-activating protein (GAP) with broad specificity. Acts as a GAP for RAB3A. Also exhibits significant GAP activity toward RAB22A, RAB27A, and RAB35 in vitro (By [...]
Cbln3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070494Cerebellin-3; May be involved in synaptic functions in the CNS.
Haus6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070504HAUS augmin-like complex, subunit 6.
Cfap58 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070533Cilia- and flagella-associated protein 58.
Fra10ac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070534Protein FRA10AC1 homolog.
Cgrrf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070548Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines.
Spats2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070549Spermatogenesis-associated serine-rich protein 2; Belongs to the SPATS2 family.
9430038I01Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000070550Uncharacterized protein C10orf143 homolog.
Tmem119 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070551Transmembrane protein 119; Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts. May induce the commitment and diff [...]
Usp46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070554Ubiquitin carboxyl-terminal hydrolase 46; Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has a [...]
Rtbdn protein networkhttps://string-db.org/network/10090.ENSMUSP00000070558Retbindin; Riboflavin-binding protein which might have a role in retinal flavin transport; Belongs to the folate receptor family.
Tll1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070560Tolloid-like protein 1; Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development, especially heart developme [...]
Tnni3k protein networkhttps://string-db.org/network/10090.ENSMUSP00000070561Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Mia2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070572Melanoma inhibitory activity protein 2; Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membra [...]
Cdkn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070575Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. D [...]
Lpin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070583Phosphatidate phosphatase LPIN1; Plays important roles in controlling the metabolism of fatty acids at different levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catal [...]
Rab13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070588Ras-related protein Rab-13; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle bet [...]
Slain1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070592SLAIN motif-containing protein 1; Microtubule plus-end tracking protein that might be involved in the regulation of cytoplasmic microtubule dynamics, microtubule organization and microtubule elon [...]
Pfdn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070596Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which the [...]
1700030J22Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000070601Uncharacterized protein C16orf46 homolog.
Lrrc49 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070606Leucine-rich repeat-containing protein 49.
Sh3tc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070610SH3 domain and tetratricopeptide repeats 1.
Rad18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070619E3 ubiquitin-protein ligase RAD18; E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap- filling of a daughter strand on repli [...]
Defb42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070629Beta-defensin 42; Has bactericidal activity (By similarity). May play a role in the antimicrobial protection of sperm and urogenital tract epithelia ; Belongs to the beta-defensin family.
Xkr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070648XK-related protein 4.
Zfp747 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070685Zinc finger protein 747.
Fabp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070709Fatty acid-binding protein, heart; FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
Wfdc15a protein networkhttps://string-db.org/network/10090.ENSMUSP00000070718WAP four-disulfide core domain protein 15A; Antibacterial protein.
Hhipl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070719HHIP-like protein 2; Belongs to the HHIP family.
Cdc42se2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070725CDC42 small effector protein 2; Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape ch [...]
Ppp2r5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000070726Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the lo [...]
Zdhhc19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070727Palmitoyltransferase ZDHHC19; Palmitoyltransferase that mediates palmitoylation of STAT3 and RRAS. Palmitoylation of STAT3 induces the homodimerization and transcriptional activation of STAT3, th [...]
Btrc protein networkhttps://string-db.org/network/10090.ENSMUSP00000070728F-box/WD repeat-containing protein 1A; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent prot [...]
Ddx60 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070741DEAD (Asp-Glu-Ala-Asp) box polypeptide 60.
Tmem74 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070748Transmembrane protein 74; Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction (By similarity). Belongs to the TMEM74 family.
Bsg protein networkhttps://string-db.org/network/10090.ENSMUSP00000070751Basigin; Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3, SLC16A8, SLC16A11 and SLC16A12 to the plasma membrane. Plays pivotal roles in spermatogenesis, emb [...]
Sugct protein networkhttps://string-db.org/network/10090.ENSMUSP00000070759Succinate--hydroxymethylglutarate CoA-transferase; Catalyzes the succinyl-CoA-dependent conversion of glutarate to glutaryl-CoA. Can use different dicarboxylic acids as CoA acceptors, the preferr [...]
Pgpep1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070778Pyroglutamyl-peptidase 1; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
Tas2r136 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070791Taste receptor type 2 member 136; Putative taste receptor which may play a role in the perception of bitterness.
Sh2d4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000070825SH2 domain-containing protein 4A; Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced [...]
BC048403 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070834KICSTOR complex protein C12orf66 homolog; As part of the KICSTOR complex functions in the amino acid- sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, [...]
Gypa protein networkhttps://string-db.org/network/10090.ENSMUSP00000070836Glycophorin-A; Glycophorin A is the major intrinsic membrane sialoglycoprotein of the erythrocyte. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. [...]
Uts2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000070840Urotensin-2B; Potent vasoconstrictor; Belongs to the urotensin-2 family.
Cd248 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070847Endosialin; May play a role in angiogenesis or vascular function.
Chat protein networkhttps://string-db.org/network/10090.ENSMUSP00000070865Choline O-acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses; Belongs to the carnitine/choline acetyltransferase fami [...]
Pla2g4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000070868Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the [...]
Pgm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070871Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylati [...]
Stambp protein networkhttps://string-db.org/network/10090.ENSMUSP00000070876STAM-binding protein; Zinc metalloprotease that specifically cleaves 'Lys-63'- linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in s [...]
Fev protein networkhttps://string-db.org/network/10090.ENSMUSP00000070878Protein FEV; Functions as a transcriptional regulator. May function as a transcriptional repressor. Functions in the differentiation and the maintenance of the central serotonergic neurons. May p [...]
Rai1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070896Retinoic acid-induced protein 1; Transcriptional regulator of the circadian clock components: CLOCK, ARNTL/BMAL1, ARNTL2/BMAL2, PER1/3, CRY1/2, NR1D1/2 and RORA/C. Positively regulates the transc [...]
Cib1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070901Calcium and integrin-binding protein 1; Calcium-binding protein that plays a role in the regulation of numerous cellular processes, such as cell differentiation, cell division, cell proliferation [...]
Ube2ql1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070906Ubiquitin-conjugating enzyme E2Q-like protein 1; Probable E2 ubiquitin-protein ligase that catalyzes the covalent attachment of ubiquitin to target proteins. May facilitate the monoubiquitination [...]
Snx32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070915Sorting nexin-32; May be involved in several stages of intracellular trafficking.
Ptafr protein networkhttps://string-db.org/network/10090.ENSMUSP00000070925Platelet-activating factor receptor; Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive act [...]
Wdr6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070927WD repeat-containing protein 6; Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy.
Ash2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000070957Set1/Ash2 histone methyltransferase complex subunit ASH2; Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not [...]
Agtr1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000070958Type-1A angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
Srsf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070983Serine/arginine-rich splicing factor 7; Required for pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histo [...]
Dbr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000070991Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently deg [...]
Ywhae protein networkhttps://string-db.org/network/10090.ENSMUSP0000007099314-3-3 protein epsilon; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recogn [...]
Rnf144b protein networkhttps://string-db.org/network/10090.ENSMUSP00000071017E3 ubiquitin-protein ligase RNF144B; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly trans [...]
Shisa6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071025Protein shisa-6; Involved in maintenance of high-frequency synaptic transmission at hippocampal CA3-CA1 synapses. Regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic den [...]
Smad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071035Mothers against decapentaplegic homolog 1; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor- regulated SMAD (R-SMAD) (By simila [...]
Psmc3 protein networkhttps://string-db.org/network/10090.ENSMUSP0000007105426S proteasome regulatory subunit 6A; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in [...]
Cyp2d12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071064Cytochrome P450, family 2, subfamily d, polypeptide 12; Belongs to the cytochrome P450 family.
Cope protein networkhttps://string-db.org/network/10090.ENSMUSP00000071078Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosy [...]
Mobp protein networkhttps://string-db.org/network/10090.ENSMUSP00000071084Myelin-associated oligodendrocyte basic protein; May play a role in compacting or stabilizing the myelin sheath possibly by binding the negatively charged acidic phospholipids of the cytoplasmic [...]
Tssk5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071120Testis-specific serine/threonine-protein kinase 5; May be involved in a signaling pathway during male germ cell development or mature sperm function; Belongs to the protein kinase superfamily. CA [...]
Alox5ap protein networkhttps://string-db.org/network/10090.ENSMUSP00000071130Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essentia [...]
Tubb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071134Tubulin beta-3 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha ch [...]
Tubb4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000071135Tubulin beta-4A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha c [...]
Klrc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071147Killer cell lectin-like receptor subfamily C, member 3.
Rffl protein networkhttps://string-db.org/network/10090.ENSMUSP00000071150E3 ubiquitin-protein ligase rififylin; E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. M [...]
Rcc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071163Protein RCC2; Multifunctional protein that may effect its functions by regulating the activity of small GTPases, such as RAC1 and RALA. Required for normal progress through the cell cycle, both d [...]
Fpr-rs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071179Formyl peptide receptor-related sequence 3; May have an olfactory function associated with the identification of pathogens or of pathogenic states.
Arl9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071188ADP-ribosylation factor-like 9.
Ppef1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071191Serine/threonine-protein phosphatase with EF-hands 1; May have a role in the recovery or adaptation response of photoreceptors. May have a role in diverse sensory neurons and in development; Belo [...]
Fuz protein networkhttps://string-db.org/network/10090.ENSMUSP00000071194Protein fuzzy homolog; Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. Proposed to function as core component of t [...]
Chchd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071202Coiled-coil-helix-coiled-coil-helix domain-containing protein 1; Belongs to the mitochondrion-specific ribosomal protein mS37 family.
Eif2s1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071214Eukaryotic translation initiation factor 2 subunit 1; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribos [...]
Pygl protein networkhttps://string-db.org/network/10090.ENSMUSP00000071231Glycogen phosphorylase, liver form; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their n [...]
2410002F23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000071265RIKEN cDNA 2410002F23 gene.
Nf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071289Neurofibromin; Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.
Bckdha protein networkhttps://string-db.org/network/10090.ENSMUSP000000712922-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It con [...]
Pcdh17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071325Protocadherin 17.
Ifnab protein networkhttps://string-db.org/network/10090.ENSMUSP00000071333Interferon alpha B.
Olfr566 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071344Olfactory receptor.
Psg16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071348Pregnancy-specific glycoprotein 16.
Elovl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071351Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endopla [...]
Ccr1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071353C-C chemokine receptor 1-like protein 1; Probable receptor for a C-C type chemokine.
Mroh5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071366Maestro heat-like repeat family member 5.
Nhlrc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071370NHL repeat-containing protein 2; Required for normal embryonic development.
Olfr919 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071372Olfactory receptor.
2310039H08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000071378Uncharacterized protein C6orf226 homolog.
Npdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071387Neural proliferation differentiation and control protein 1; Suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell proliferation. Might be involved in t [...]
Olfr25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071393Olfactory receptor.
Fam136a protein networkhttps://string-db.org/network/10090.ENSMUSP00000071426Protein FAM136A; Belongs to the FAM136 family.
Ctsj protein networkhttps://string-db.org/network/10090.ENSMUSP00000071457Cathepsin J; Belongs to the peptidase C1 family.
Dach1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071464Dachshund homolog 1; Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in [...]
Mgam protein networkhttps://string-db.org/network/10090.ENSMUSP00000071466Maltase-glucoamylase.
Ifitm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071470Interferon-induced transmembrane protein 2; IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral f [...]
Actg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071486Actin, cytoplasmic 2, N-terminally processed; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Olfr815 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071488Olfactory receptor.
Ovca2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071493Esterase OVCA2; Belongs to the LovG family.
Cracr2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000071494EF-hand calcium-binding domain-containing protein 4B; Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as [...]
Fbh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071495F-box DNA helicase 1; 3'-5' DNA helicase and substrate-recognition component of the SCF(FBH1) E3 ubiquitin ligase complex that plays a key role in response to stalled/damaged replication forks (B [...]
Gm10436 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071508Predicted gene 10436.
Oprl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071513Nociceptin receptor; G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling v [...]
Nkx6-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071517Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas.
Prmt7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071521Protein arginine N-methyltransferase 7; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a prefere [...]
Olfr943 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071545Olfactory receptor.
Rdh16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071573Retinol dehydrogenase 16; Oxidoreductase with a preference for NAD. Oxidizes all-trans- retinol, 9-cis-retinol, 11-cis-retinol and 13-cis-retinol to the corresponding aldehydes. Has higher activi [...]
Idua protein networkhttps://string-db.org/network/10090.ENSMUSP00000071577Alpha-L-iduronidase.
Mthfd2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000071578Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2.
Olfr480 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071583Olfactory receptor 480; Probable odorant receptor, which recognizes only aliphatic alcohols, suggesting that it may convey a 'woody' or 'sweet' sour. Belongs to the G-protein coupled receptor 1 f [...]
Psmd4 protein networkhttps://string-db.org/network/10090.ENSMUSP0000007158926S proteasome non-ATPase regulatory subunit 4; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a k [...]
Taar7f protein networkhttps://string-db.org/network/10090.ENSMUSP00000071611Trace amine-associated receptor 7f; Olfactory receptor activated by trace amine N- methylpiperidine. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cy [...]
Tas2r123 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071615Taste receptor type 2 member 123; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calc [...]
Rpl7 protein networkhttps://string-db.org/network/10090.ENSMUSP0000007161660S ribosomal protein L7; Component of the large ribosomal subunit (By similarity). Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhi [...]
Erlin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071618Erlin-1; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5- trisphosphate receptors (IP3Rs). Involved in regulation o [...]
Tut7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071623Terminal uridylyltransferase 7; Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay. Esse [...]
Tas2r120 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071626Taste receptor type 2 member 120; Putative taste receptor which may play a role in the perception of bitterness.
Frem1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071627FRAS1-related extracellular matrix protein 1; Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development; Belo [...]
Zfp36l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071630mRNA decay activator protein ZFP36L3; Placenta-specific zinc-finger RNA-binding protein that destabilizes cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) [...]
Prdx6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071636Peroxiredoxin-6; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H(2)O(2) and short chain or [...]
Olfr39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071641Olfactory receptor.
Gsk3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000071654Glycogen synthase kinase-3 alpha; Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcript [...]
Col12a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071662Collagen alpha-1(XII) chain; Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains [...]
Gm14496 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071670Predicted gene 14496.
Nptx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071687Neuronal pentraxin-2; Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner (By similarity).
Zkscan7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071695Zinc finger with KRAB and SCAN domains 7.
1110038F14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000071698UPF0488 protein C8orf33 homolog.
AI987944 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071708Expressed sequence AI987944.
Iqgap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071715IQ motif-containing GTPase-activating protein 3.
Ficd protein networkhttps://string-db.org/network/10090.ENSMUSP00000071719Protein adenylyltransferase FICD; Protein that can both mediate the addition of adenosine 5'- monophosphate (AMP) to specific residues of target proteins (AMPylation), and the removal of the same [...]
Camk2g protein networkhttps://string-db.org/network/10090.ENSMUSP00000071720Calcium/calmodulin-dependent protein kinase type II subunit gamma; Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, [...]
Klhdc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071743Kelch domain-containing protein 3; May be involved in meiotic recombination process.
Fmr1nb protein networkhttps://string-db.org/network/10090.ENSMUSP00000071748Fragile X mental retardation 1 neighbor protein.
Commd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071752COMM domain-containing protein 7; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Associates with the NF-kappa-B complex and suppresses its transcriptional activity.
Hpcal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071756Hippocalcin-like protein 1; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.
Serpinb9e protein networkhttps://string-db.org/network/10090.ENSMUSP00000071769Serine (Or cysteine) peptidase inhibitor, clade B, member 9e; Belongs to the serpin family.
Ano6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071770Anoctamin-6; Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets, osteoblasts and fetal thymocytes. Phospholip [...]
Cdpf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071772Cysteine-rich DPF motif domain-containing protein 1; Belongs to the CDPF1 family.
Myo15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071777Unconventional myosin-XV; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind [...]
Rhox8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071782Reproductive homeobox 8.
Defa39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071783Defensin, alpha, 39.
Car12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071786Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family.
Elac2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071788Zinc phosphodiesterase ELAC protein 2; Zinc phosphodiesterase, which displays mitochondrial tRNA 3'- processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from p [...]
Cpsf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071794Cleavage and polyadenylation specificity factor subunit 1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, reco [...]
Adra2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000071798Alpha-2B adrenergic receptor; Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins; Belongs to the G-protein coupled re [...]
Fbxw26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071811F-box and WD-40 domain protein 26.
Dmtf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071815Cyclin-D-binding Myb-like transcription factor 1; Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53- dependent growth arr [...]
Nol7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071818Nucleolar protein 7.
Kcnj14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071829ATP-sensitive inward rectifier potassium channel 14; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Th [...]
Tec protein networkhttps://string-db.org/network/10090.ENSMUSP00000071836Tyrosine-protein kinase Tec; Non-receptor tyrosine kinase that contributes to signaling from many receptors and participates as a signal transducer in multiple downstream pathways, including regu [...]
Bloc1s4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071840Biogenesis of lysosome-related organelles complex 1 subunit 4; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as plat [...]
H2-Q7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071843H-2 class I histocompatibility antigen, Q7 alpha chain; Involved in the presentation of foreign antigens to the immune system.
Trpv4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071859Transient receptor potential cation channel subfamily V member 4; Non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to h [...]
Cfap57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071863Cilia- and flagella-associated protein 57.
Ero1lb protein networkhttps://string-db.org/network/10090.ENSMUSP00000071864ERO1-like protein beta; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in or [...]
Mfap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071868Microfibrillar-associated protein 2; Component of the elastin-associated microfibrils.
Olfr1329 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071870Olfactory receptor 1329.
Bmper protein networkhttps://string-db.org/network/10090.ENSMUSP00000071872BMP-binding endothelial regulator protein; Inhibitor of bone morphogenetic protein (BMP) function, it may regulate BMP responsiveness of osteoblasts and chondrocytes.
Slco4c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071875Solute carrier organic anion transporter family member 4C1; Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAM [...]
Mia protein networkhttps://string-db.org/network/10090.ENSMUSP00000071876Melanoma-derived growth regulatory protein; Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
Dppa5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000071881Developmental pluripotency-associated protein 5A; Involved in the maintenance of embryonic stem (ES) cell pluripotency. Dispensable for self-renewal of pluripotent ES cells and establishment of g [...]
Sh3rf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071896E3 ubiquitin-protein ligase SH3RF2; Has E3 ubiquitin-protein ligase activity. Acts as an anti- apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a [...]
Adtrp protein networkhttps://string-db.org/network/10090.ENSMUSP00000071899Androgen-dependent TFPI-regulating protein; Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids (By similarity). Shows a preference for F [...]
Alms1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071904Alstrom syndrome protein 1 homolog; Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. Requir [...]
Tle6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071905Transducin-like enhancer protein 6; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.
Mprip protein networkhttps://string-db.org/network/10090.ENSMUSP00000071914Myosin phosphatase Rho-interacting protein; Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an in [...]
Olfr486 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071918Olfactory receptor 486; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Entpd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071939Ectonucleoside triphosphate diphosphohydrolase 5; Uridine diphosphatase (UDPase) that promotes protein N- glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation a [...]
Rrs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071955Ribosome biogenesis regulatory protein homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.
Lrrc40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071956Leucine-rich repeat-containing protein 40.
Plxnb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071966Plexin-B1; Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent [...]
Hsh2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000071970Hematopoietic SH2 domain-containing protein; Adapter protein involved in tyrosine kinase and CD28 signaling (By similarity). May be a modulator of the apoptotic response through its ability to af [...]
Try10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071976Trypsinogen 10; Belongs to the peptidase S1 family.
Tmem65 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071984Transmembrane protein 65; May play an important role in cardiac development and function. May regulate cardiac conduction and the function of the gap junction protein GJA1. May contribute to the [...]
Olfr338 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071985Olfactory receptor.
Ccnb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000071989G2/mitotic-specific cyclin-B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily.
Gm10226 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072002Predicted gene 10226.
Pdcd11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072008Protein RRP5 homolog; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA (By simila [...]
Pigh protein networkhttps://string-db.org/network/10090.ENSMUSP00000072018Phosphatidylinositol N-acetylglucosaminyltransferase subunit H; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first [...]
Ccdc189 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072019Coiled-coil domain-containing protein 189.
Tiam2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072020T-lymphoma invasion and metastasis-inducing protein 2; Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimu [...]
Rhox2e protein networkhttps://string-db.org/network/10090.ENSMUSP00000072030Reproductive homeobox 2E.
Nuak2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072039NUAK family SNF1-like kinase 2; Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induce [...]
Sim2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072043Single-minded homolog 2; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development.
Klk1b8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072063Kallikrein 1-related peptidase b8; Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin; Belongs to the peptidase S1 family. Kallikrein subfamily.
Poc1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000072064POC1 centriolar protein homolog A; Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps [...]
Ggt5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072074Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4).
Zfp329 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072079Zinc finger protein 329; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Gckr protein networkhttps://string-db.org/network/10090.ENSMUSP00000072084Glucokinase regulatory protein; Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK [...]
Tmod3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072087Tropomodulin-3; Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in t [...]
1700019A02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000072089RIKEN cDNA 1700019A02 gene.
Mink1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072091Misshapen-like kinase 1; Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. R [...]
Grik1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072107Glutamate receptor ionotropic, kainate 1; Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitato [...]
Mageb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072119Melanoma antigen, family B, 1.
Etnppl protein networkhttps://string-db.org/network/10090.ENSMUSP00000072121Ethanolamine-phosphate phospho-lyase; Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde.
Krtap8-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072129Keratin-associated protein 8-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Gm5862 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072133Predicted gene 5862.
Flot2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072136Flotillin-2; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion [...]
Vsnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072145Visinin-like protein 1; Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner; Belongs to the recoverin family.
Gm11938 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072150Keratin-associated protein 2-4.
Yes1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072154Tyrosine-protein kinase Yes; Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and diffe [...]
Usp13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072155Ubiquitin carboxyl-terminal hydrolase 13; Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autopha [...]
Dtnbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072170Dysbindin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with [...]
Dnajc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072175DnaJ homolog subfamily C member 5; Acts as a co-chaperone for the SNARE protein SNAP-25. Involved in the calcium-mediated control of a late stage of exocytosis. Acts as a general chaperone in reg [...]
Tpm3-rs7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072197Tropomyosin 3, related sequence 7; Belongs to the tropomyosin family.
Kprp protein networkhttps://string-db.org/network/10090.ENSMUSP00000072200Keratinocyte proline-rich protein.
Washc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072220WASH complex subunit 1; Acts as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in [...]
H2ac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072227Histone H2A; Belongs to the histone H2A family.
Ugt3a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072236UDP-glucuronosyltransferase 3A2; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water so [...]
Tas2r104 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072237Taste receptor type 2 member 104; Putative taste receptor which may play a role in the perception of bitterness.
Olfr854 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072248Olfactory receptor.
Cyp2b10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072264Cytochrome P450 2B10; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a va [...]
Slc9a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072274Sodium/hydrogen exchanger 7; Mediates electroneutral exchange of protons for Na(+) and K(+) across endomembranes. May contribute to the regulation of Golgi apparatus volume and pH.
Lhb protein networkhttps://string-db.org/network/10090.ENSMUSP00000072276Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
Zfp809 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072286Zinc finger protein 809; Transcription factor specifically required to repress retrotransposons in embryonic stem cells. Recognizes and binds retroviral DNA sequences from a large subset of mamma [...]
Vmn2r30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072296Vomeronasal 2, receptor 30.
Oas1h protein networkhttps://string-db.org/network/10090.ENSMUSP000000722972',5'-oligoadenylate synthetase-like 6.
Myod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072330Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 an [...]
Tgif2lx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072333TGFB-induced factor homeobox 2-like, X-linked 1.
Elmo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072334Engulfment and cell motility protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initial [...]
Adgrl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072336Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays [...]
Csn1s2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000072352Alpha-S2-casein-like B; Important role in the capacity of milk to transport calcium phosphate.
Alg11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072382GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic [...]
Srp19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072386Signal recognition particle 19 kDa protein; Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
Ube2d2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000072387Ubiquitin-conjugating enzyme E2 D2B; Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6 [...]
Gps2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072389G protein pathway suppressor 2; Key regulator of inflammation, lipid metabolism and mitochondrion homeostasis that acts by inhibiting the activity of the ubiquitin-conjugating enzyme UBE2N/Ubc13, [...]
Ssxa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072395Protein SSXA1; Could act as a modulator of transcription.
Ntng1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072397Netrin-G1; Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites.
Nkx2-9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072425Homeobox protein Nkx-2.8; Possible role in the specification of a distinct subset of neurons.
Aplp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072428Amyloid-like protein 2; May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signalin [...]
Olfr46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072445Olfactory receptor.
Zscan5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000072449Zinc finger and SCAN domain-containing 5B.
Mup13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072466Major urinary protein 11; Belongs to the calycin superfamily. Lipocalin family.
Tle1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072481Transducin-like enhancer protein 1; Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activa [...]
Acadm protein networkhttps://string-db.org/network/10090.ENSMUSP00000072483Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utiliz [...]
Wdr7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072509WD repeat-containing protein 7.
Ms4a4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000072512Membrane-spanning 4-domains, subfamily A, member 4C.
Olfr251 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072514Olfactory receptor.
Fam173a protein networkhttps://string-db.org/network/10090.ENSMUSP00000072518Adenine nucleotide translocase lysine N-methyltransferase; Mitochondrial protein-lysine N-methyltransferase that trimethylates adenine nucleotide translocases ANT2/SLC25A5 and ANT3/SLC25A6, there [...]
Vipas39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072527Spermatogenesis-defective protein 39 homolog; Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the ap [...]
Ms4a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072531Membrane-spanning 4-domains subfamily A member 10; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family.
Dohh protein networkhttps://string-db.org/network/10090.ENSMUSP00000072534Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation [...]
Cyp2d10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072555Cytochrome P450 2D10; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a va [...]
Vmn2r37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072566Vomeronasal 2, receptor 37.
Sox6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072583Transcription factor SOX-6; Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleto [...]
Zfp954 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072585Zinc finger protein 954.
Ugt2b38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072598UDP glucuronosyltransferase 2 family, polypeptide B38.
Ccdc112 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072614Coiled-coil domain-containing protein 112.
Foxk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072616Forkhead box protein K1; Transcriptional regulator involved in different processes such as glucose metabolism, aerobic glycolysis, muscle cell differentiation and autophagy. Recognizes and binds [...]
Hsf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072617Heat shock factor protein 1; Functions as a stress-inducible and DNA-binding transcription factor that plays a central role in the transcriptional activation of the heat shock response (HSR), lea [...]
Olfr340 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072632Olfactory receptor.
Scfd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072636Sec1 family domain-containing protein 2; May be involved in protein transport; Belongs to the STXBP/unc-18/SEC1 family.
Ubap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072643Ubiquitin-associated protein 1; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic [...]
Kcns2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072645Potassium voltage-gated channel subfamily S member 2; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB [...]
Serpina1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000072652Alpha-1-antitrypsin 1-1; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Belongs to the serpin family.
Sctr protein networkhttps://string-db.org/network/10090.ENSMUSP00000072660Secretin receptor; Receptor for secretin (SCT), which is involved in different processes such as regulation of the pH of the duodenal content, food intake and water homeostasis. The activity of t [...]
Carmil1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072662F-actin-uncapping protein LRRC16A; Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin [...]
Armc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072669Armadillo repeat-containing protein 10; May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53 (By similarity).
Cgnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072672Cingulin-like protein 1; May be involved in anchoring the apical junctional complex, especially tight junctions, to actin-based cytoskeletons. Belongs to the cingulin family.
Chadl protein networkhttps://string-db.org/network/10090.ENSMUSP00000072682Chondroadherin-like protein; Potential negative modulator of chondrocyte differentiation. Inhibits collagen fibrillogenesis in vitro. May influence chondrocyte's differentiation by acting on its [...]
Olfr508 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072686Olfactory receptor 508; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Foxb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072687Forkhead box protein B2; Transcription factor.
Zswim7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072688Zinc finger SWIM domain-containing protein 7; Involved in early stages of the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced [...]
Tmem40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072704Transmembrane protein 40.
Slc6a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072709Sodium-dependent noradrenaline transporter; Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals. Belongs to the sod [...]
Prl7c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072712Prolactin-7C1.
Vps41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072729Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pa [...]
Sirt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072732NAD-dependent protein deacetylase sirtuin-2; NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcr [...]
Olfr883 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072741Olfactory receptor MOR162-6.
Olfr773 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072743Olfactory receptor.
Postn protein networkhttps://string-db.org/network/10090.ENSMUSP00000072773Periostin; Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic acti [...]
Cxcl12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072800Stromal cell-derived factor 1; Chemoattractant active on T-lymphocytes and monocytes but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the [...]
Ugt1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072803UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
Mppe1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072808Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation [...]
Gm10053 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072829Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. [...]
1700010B08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000072830RIKEN cDNA 1700010B08 gene.
Miga1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072836Mitoguardin 1; Regulator of mitochondrial fusion. Acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regu [...]
Olfr675 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072847Olfactory receptor.
Ppp4r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072848Serine/threonine-protein phosphatase 4 regulatory subunit 1; Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The P [...]
Ctdspl protein networkhttps://string-db.org/network/10090.ENSMUSP00000072852CTD small phosphatase-like protein; Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II s [...]
Gm10061 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072854Predicted gene 10061.
H2ac21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072858Histone H2A type 2-B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
Ppox protein networkhttps://string-db.org/network/10090.ENSMUSP00000072863Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
Olfr871 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072865Olfactory receptor.
Zfp746 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072868Zinc finger protein 746; Transcription repressor that specifically binds to the 5'- TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby pla [...]
Ncapd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072871Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid ax [...]
Ndrg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072883Protein NDRG4; Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell [...]
Slc9a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072893Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
Peli2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072894E3 ubiquitin-protein ligase pellino homolog 2; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL- 1 signaling pathwa [...]
Nlrp9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000072895NACHT, LRR and PYD domains-containing protein 9B; As the sensor component of the NLRP9 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens, including [...]
Fastkd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072896FAST kinase domain-containing protein 1, mitochondrial; Involved in the down-regulation of mitochondrial MT-ND3 mRNA levels which leads to decreased respiratory complex I abundance and activity.
Zfp65 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072900Zinc finger protein 65.
Ppp1r14bl protein networkhttps://string-db.org/network/10090.ENSMUSP00000072920Protein phosphatase 1, regulatory inhibitor subunit 14B-like.
Erlec1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072929Endoplasmic reticulum lectin 1; Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-assoc [...]
H2-Q1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072942Histocompatibility 2, Q region locus 1; Belongs to the MHC class I family.
Myom1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072945Myomesin-1; May link the intermediate filament cytoskeleton to the M-disk of the myofibrils in striated muscle. May also contact myosin filaments. Also binds beta-integrins.
Slc52a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072961Solute carrier family 52, riboflavin transporter, member 3; Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemic [...]
Olfr1537 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072979Olfactory receptor 1537; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Ccdc177 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072982Coiled-coil domain-containing protein 177.
Chrnd protein networkhttps://string-db.org/network/10090.ENSMUSP00000072983Acetylcholine receptor subunit delta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting cha [...]
H2ac10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000072989Histone H2A type 1-F; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
Gsdma3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073022Gasdermin-A3; May play a role in the transition from catagen to telogen at the end of hair follicle morphogenesis. May promote pyroptosis. Upon cleavage in vitro of genetically engineered Gsdma3, [...]
Zfp760 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073038Zinc finger protein 760.
Foxm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073041Forkhead box protein M1; Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays a [...]
Pgrmc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073061Membrane-associated progesterone receptor component 1; Component of a progesterone-binding protein complex. Binds progesterone. Has many reported cellular functions (heme homeostasis, interaction [...]
Ctse protein networkhttps://string-db.org/network/10090.ENSMUSP00000073072Cathepsin E; May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced [...]
Amtn protein networkhttps://string-db.org/network/10090.ENSMUSP00000073081Amelotin; Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of a [...]
Fam120c protein networkhttps://string-db.org/network/10090.ENSMUSP00000073082Constitutive coactivator of PPAR-gamma-like protein 2.
Ms4a13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073095Membrane-spanning 4-domains subfamily A member 13; May be involved in signal transduction as a component of a multimeric receptor complex.
Epha1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073099Ephrin type-A receptor 1; Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signali [...]
Afmid protein networkhttps://string-db.org/network/10090.ENSMUSP00000073102Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized [...]
Cyp26c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073105Cytochrome P450, family 26, subfamily c, polypeptide 1; Belongs to the cytochrome P450 family.
Usp17ld protein networkhttps://string-db.org/network/10090.ENSMUSP00000073107Ubiquitin carboxyl-terminal hydrolase 17-like protein D; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include [...]
Plec protein networkhttps://string-db.org/network/10090.ENSMUSP00000073124Plectin; Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. May be involved not only in the cross-linking a [...]
Pcdhga3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073150Protocadherin gamma subfamily A, 3.
Nsa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073161Ribosome biogenesis protein NSA2 homolog; Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity).
Syt9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073164Synaptotagmin-9; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of ves [...]
Cryzl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073171Quinone oxidoreductase-like protein 1.
Olfr290 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073172Olfactory receptor.
Nr1h2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073188Oxysterols receptor LXR-beta; Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity. Binds preferentially to double-stranded oligonucleotide direct repeats having [...]
Lct protein networkhttps://string-db.org/network/10090.ENSMUSP00000073190Lactase.
Thsd7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000073220Thrombospondin type-1 domain-containing protein 7B.
Zar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073221Zygote arrest protein 1; Essential for female fertility. May play a role in the oocyte-to-embryo transition; Belongs to the ZAR1 family.
Gm13089 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073224Predicted gene 13089.
Zfp523 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073226Zinc finger protein 76; May be involved in transcriptional regulation.
Nrap protein networkhttps://string-db.org/network/10090.ENSMUSP00000073228Nebulin-related-anchoring protein; May be involved in anchoring the terminal actin filaments in the myofibril to the membrane and in transmitting tension from the myofibrils to the extracellular [...]
H2-M10.3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073236Major histocompatibility complex class Ib M10.3; Belongs to the MHC class I family.
Cytl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073244Cytokine-like protein C17.
Mdga1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073246MAM domain-containing glycosylphosphatidylinositol anchor protein 1; Required for radial migration of cortical neurons in the superficial layer of the neocortex. Plays a role in the formation or [...]
Zfp414 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073259Zinc finger protein 414; May be involved in transcriptional regulation.
Mtx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073261Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development.
Prkg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073268cGMP-dependent protein kinase 1; Serine/threonine protein kinase that acts as key mediator of the nitric oxide (NO)/cGMP signaling pathway. GMP binding activates PRKG1, which phosphorylates serin [...]
Prl3d3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073286Prolactin family 3, subfamily d, member 3.
Glipr1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073302GLIPR1-like protein 1; Plays a role in the binding between sperm and oocytes. Component of epididymosomes, one type of membranous microvesicules which mediate the transfer of lipids and proteins [...]
Inca1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073311Protein INCA1; Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor. Inhibits cell growth and proliferation and m [...]
Rdh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073322Retinol dehydrogenase 1 (All trans); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Oog4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073325Oog4 protein.
Tmsb15a protein networkhttps://string-db.org/network/10090.ENSMUSP00000073355Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymos [...]
Lima1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073371LIM domain and actin-binding protein 1; Actin-binding protein involved in actin cytoskeleton regulation and dynamics. Increases the number and size of actin stress fibers and inhibits membrane ru [...]
Klk1b24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073392Kallikrein 1-related peptidase b24; Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin; Belongs to the peptidase S1 family. Kallikrein subfamily.
1700001J03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000073399RIKEN cDNA 1700001J03 gene.
Phf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073402PHD finger protein 1; Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Involved in DNA damage response and is recruited [...]
Ugt1a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073444UDP-glucuronosyltransferase 1-9; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
E2f7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073453Transcription factor E2F7; Atypical E2F transcription factor that participates in various processes such as angiogenesis, polyploidization of specialized cells and DNA damage response. Mainly act [...]
Akr7a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073459Aflatoxin B1 aldehyde reductase member 2; Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gam [...]
Mon2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073462Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Belongs to the MON2 family.
Mrgpra6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073463Mas-related G-protein coupled receptor member A6; Orphan receptor. May be a receptor for RFamide-family neuropeptides such as NPFF and NPAF, which are analgesic in vivo. May regulate nociceptor f [...]
Lrrc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073502Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.
Pou6f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073504POU domain, class 6, transcription factor 1; Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3').
Gm11562 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073519Predicted gene 11562.
Tgif2lx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073522TGFB-induced factor homeobox 2-like, X-linked 1.
Ang4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073525Angiogenin-4; Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). P [...]
Dupd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073534Dual specificity phosphatase DUPD1; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a s [...]
Dhcr7 protein networkhttps://string-db.org/network/10090.ENSMUSP000000735417-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).
Nrg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073546Neuregulin-1 type III beta1-a.
Polg protein networkhttps://string-db.org/network/10090.ENSMUSP00000073551DNA polymerase subunit gamma-1; Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA (By similarity); Belongs to the DNA polymerase type-A family.
Krt33b protein networkhttps://string-db.org/network/10090.ENSMUSP00000073552Keratin, type I cuticular Ha3-II; Belongs to the intermediate filament family.
Fxyd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073555FXYD domain-containing ion transport regulator 7.
Olfr952 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073558Olfactory receptor MOR171-21.
2810021J22Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000073579RIKEN cDNA 2810021J22 gene.
Gsg1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000073591Germ cell-specific gene 1-like protein; As a component of the inner core of AMPAR complexes, modifies AMPA receptor (AMPAR) gating; Belongs to the GSG1 family.
Vmn2r19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073604Vomeronasal 2, receptor 19.
H2al1m protein networkhttps://string-db.org/network/10090.ENSMUSP00000073605Histone H2A; Belongs to the histone H2A family.
Sema3e protein networkhttps://string-db.org/network/10090.ENSMUSP00000073612Semaphorin-3E; Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promote [...]
Fbxw24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073617F-box and WD-40 domain protein 24.
Sipa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073618Signal-induced proliferation-associated protein 1; GTPase activator for the nuclear Ras-related regulatory proteins Rap1, Rsr1 and Ran in vitro, converting them to the putatively inactive GDP-bou [...]
Vmn1r177 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073621Vomeronasal type-1 receptor.
Ube3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000073652Ubiquitin-protein ligase E3B; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to t [...]
Negr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073664Neuronal growth regulator 1; May be involved in cell-adhesion. May function as a trans- neural growth-promoting factor in regenerative axon sprouting in the mammalian brain.
Mup20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073667Major urinary protein 20; Male pheromone which stimulates female sexual attraction to male urinary scent and promotes a strong learned attraction to the airborne urinary odor of an individual mal [...]
Klf10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073690Krueppel-like factor 10; Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. May play a role in the cell cycle regulation (By similarity). Plays a role in the regulation [...]
Elmo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073691Engulfment and cell motility protein 2; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initial [...]
Serpina1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000073695Alpha-1-antitrypsin 1-3; Inhibitor of serine proteases. Can inhibit trypsin and chymotrypsin; relatively ineffective against elastase. Belongs to the serpin family.
Sap18b protein networkhttps://string-db.org/network/10090.ENSMUSP00000073697Histone deacetylase complex subunit SAP18; Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can [...]
Klra6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073700Killer cell lectin-like receptor 6; Receptor on natural killer (NK) cells for class I MHC.
Mbd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073701Methyl-CpG-binding domain protein 2; Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits hist [...]
4930516K23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000073707Olfactory receptor.
Bmp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073720Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicl [...]
Prom1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073751Prominin-1; May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization [...]
Aldh3a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073764Aldehyde dehydrogenase family 3 member A2; Catalyzes the oxidation of medium and long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehyde [...]
Lce1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073776Late cornified envelope 1A1.
Dcaf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073778DDB1- and CUL4-associated factor 8; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat DCAF8 family.
Gm7361 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073781Predicted gene 7361.
Ak8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073789Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest a [...]
Myo5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000073790Unconventional myosin-Vb; May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not fo [...]
Otof protein networkhttps://string-db.org/network/10090.ENSMUSP00000073803Otoferlin; Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion and in the control of neurotransmitter release at these output synapses. Interacts in a [...]
Spatc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073805Speriolin; Belongs to the speriolin family.
Slc6a15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073829Sodium-dependent neutral amino acid transporter B(0)AT2; Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for methionine and for the branched- chain amino acids [...]
Ndufaf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073832NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3; Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
Olfr1502 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073843Olfactory receptor.
Cpne6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073847Copine-6; Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Binds phospholipid membranes in a calcium-dependent manner. Plays a role in [...]
Etd protein networkhttps://string-db.org/network/10090.ENSMUSP00000073854Embryonic testis differentiation protein.
Synm protein networkhttps://string-db.org/network/10090.ENSMUSP00000073855Synemin; Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its i [...]
Dipk1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000073860Divergent protein kinase domain 1B.
Sh2d3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000073866SH2 domain-containing protein 3C; Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 is required to induce membrane ruffling and promote EGF-depende [...]
Krt40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073869Keratin, type I cytoskeletal 40; May play a role in late hair differentiation.
Nrm protein networkhttps://string-db.org/network/10090.ENSMUSP00000073873Nurim.
Calcrl protein networkhttps://string-db.org/network/10090.ENSMUSP00000073875Calcitonin gene-related peptide type 1 receptor; Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity [...]
Rps7 protein networkhttps://string-db.org/network/10090.ENSMUSP0000007388040S ribosomal protein S7; Required for rRNA maturation.
Smyd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073911Histone-lysine N-methyltransferase Smyd1; Methylates histone H3 at 'Lys-4' (H3K4me). Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.
Defa26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073950Alpha-defensin 26; May have microbicidal activities; Belongs to the alpha-defensin family.
Osbpl1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000073957Oxysterol-binding protein-related protein 1; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Stabilizes GTP-bound RAB7A on [...]
Klk1b5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073964Kallikrein 1-related peptidase b5; Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin; Belongs to the peptidase S1 family. Kallikrein subfamily.
Slc35f4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073972Solute carrier family 35 member F4; Putative solute transporter.
Axin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073974Axin-1; Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling (By similarity). Controls [...]
Pdcd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073975Programmed cell death protein 4; Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicas [...]
Irx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073976Iroquois-class homeodomain protein IRX-2.
Tex33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000073984Testis-expressed protein 33.
Ifnlr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074009Interferon lambda receptor 1; The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activ [...]
Prima1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074017Proline-rich membrane anchor 1; Required to anchor acetylcholinesterase (ACHE) to the basal lamina of the neuromuscular junction and to the membrane of neuronal synapses in brain. Also able to or [...]
Efcab14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074025EF-hand calcium-binding domain-containing protein 14.
Zfp772 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074055Zinc finger protein 772.
Prdm10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074104PR domain zinc finger protein 10; May be involved in transcriptional regulation.
Gulp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074115PTB domain-containing engulfment adapter protein 1; Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization of various LRP1 ligands, such as PSAP (B [...]
Jazf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074129Juxtaposed with another zinc finger protein 1; Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2 (By similarity). Inhibits expression of the gluconeogenesis enzyme PCK2 throu [...]
H2aj protein networkhttps://string-db.org/network/10090.ENSMUSP00000074142Histone H2A.J; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones ther [...]
Unc5cl protein networkhttps://string-db.org/network/10090.ENSMUSP00000074159UNC5C-like protein; Inhibits NF-kappa-B-dependent transcription by impairing NF- kappa-B binding to its targets; Belongs to the unc-5 family.
Snrnp70 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074160U1 small nuclear ribonucleoprotein 70 kDa; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome [...]
Cd302 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074188CD302 antigen; Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration.
1700029P11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000074190RIKEN cDNA 1700029P11 gene.
Olfr881 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074193Olfactory receptor MOR162-7.
Acyp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074195Acylphosphatase-2.
Nfatc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074198Nuclear factor of activated T-cells, cytoplasmic 2; Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF [...]
Xlr3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000074199X-linked lymphocyte-regulated protein 3A.
Brinp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074201BMP/retinoic acid-inducible neural-specific protein 3; Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, [...]
Wbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074204WW domain-binding protein 2; Acts as transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation. In presence of estrogen, binds to ESR1-responsive p [...]
Krtap6-5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074211Keratin-associated protein 6-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
8030462N17Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000074225Uncharacterized protein C18orf25 homolog.
T protein networkhttps://string-db.org/network/10090.ENSMUSP00000074236T-box transcription factor T; Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates ge [...]
Ubxn11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074255UBX domain-containing protein 11; May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13 (By similarity) [...]
Serpina11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074258Serpin A11.
Gnai1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074259Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous sig [...]
Esx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074262Extraembryonic, spermatogenesis, homeobox 1.
Mup2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074264Major urinary protein 2; Belongs to the calycin superfamily. Lipocalin family.
Dgkh protein networkhttps://string-db.org/network/10090.ENSMUSP00000074290Diacylglycerol kinase.
Olfr512 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074291Olfactory receptor.
Olfr920 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074300Olfactory receptor.
H2ac15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074310Histone H2A type 1-K; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
Hmcn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074340Hemicentin-1; Promotes cleavage furrow maturation during cytokinesis in preimplantation embryos. May play a role in the architecture of adhesive and flexible epithelial cell junctions. May play a [...]
Mtfmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000074347Methionyl-tRNA formyltransferase, mitochondrial; Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechani [...]
Lrig3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074360Leucine-rich repeats and immunoglobulin-like domains protein 3; Plays a role in craniofacial and inner ear morphogenesis during embryonic development. Acts within the otic vesicle epithelium to c [...]
Tlr12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074381Toll-like receptor 12; Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response [...]
Ear2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074386Eosinophil cationic protein 2; Cytotoxin and helminthotoxin with ribonuclease activity. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.
Preb protein networkhttps://string-db.org/network/10090.ENSMUSP00000074387Prolactin regulatory element-binding protein; Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat compone [...]
Tacc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074394Transforming acidic coiled-coil-containing protein 3; Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-medi [...]
Bcas3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074416Breast carcinoma-amplified sequence 3 homolog; Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase ac [...]
Gfral protein networkhttps://string-db.org/network/10090.ENSMUSP00000074421GDNF family receptor alpha-like; Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon [...]
Gm6812 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074433Predicted gene 6812.
Hp protein networkhttps://string-db.org/network/10090.ENSMUSP00000074436Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to [...]
Borcs7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074447BLOC-1-related complex subunit 7; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BO [...]
Lamp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074448Lysosome-associated membrane glycoprotein 2; Plays an important role in chaperone-mediated autophagy, a process that mediates lysosomal degradation of proteins in response to various stresses and [...]
Krtap2-4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074461Keratin associated protein 2-4.
Irak4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074471Interleukin-1 receptor-associated kinase 4; Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like recept [...]
Zfp35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074475Zinc finger protein 271; May act to control gene activity during the pachytene stage of meiotic prophase. May function as a transcription activator.
Vmn2r50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074476Vomeronasal 2, receptor 50.
Tmem140 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074482Transmembrane protein 140.
Bud13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074490BUD13 homolog; Involved in pre-mRNA splicing as component of the activated spliceosome; Belongs to the CWC26 family.
Bbs5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074494Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is [...]
Olfr836 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074514Olfactory receptor.
Tmem184b protein networkhttps://string-db.org/network/10090.ENSMUSP00000074518Transmembrane protein 184B; May activate the MAP kinase signaling pathway; Belongs to the TMEM184 family.
Helz protein networkhttps://string-db.org/network/10090.ENSMUSP00000074533Probable helicase with zinc finger domain; May act as a helicase that plays a role in RNA metabolism in multiple tissues and organs within the developing embryo.
Vpreb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074537Immunoglobulin iota chain; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in [...]
Olfr1185-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074542Olfactory receptor.
Unc13d protein networkhttps://string-db.org/network/10090.ENSMUSP00000074549Protein unc-13 homolog D; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates a [...]
Gm13084 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074557Predicted gene 13084.
Kcnh7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074563Potassium voltage-gated channel subfamily H member 7; Pore-forming (alpha) subunit of voltage-gated potassium channel (By similarity). Channel properties may be modulated by cAMP and subunit asse [...]
Hcst protein networkhttps://string-db.org/network/10090.ENSMUSP00000074573Hematopoietic cell signal transducer; Transmembrane adapter protein which associates with KLRK1 to form an activation receptor KLRK1-HCST in lymphoid and myeloid cells; this receptor plays a majo [...]
Ntm protein networkhttps://string-db.org/network/10090.ENSMUSP00000074578Neurotrimin; Neural cell adhesion molecule; Belongs to the immunoglobulin superfamily. IgLON family.
Gpr65 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074581Psychosine receptor; Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids (By similarity). Plays a role in immune response by maintaining lysosome function a [...]
Trim58 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074594E3 ubiquitin-protein ligase TRIM58; E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1 [...]
Vmn2r24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074602Vomeronasal 2, receptor 24.
Vmn2r31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074613Vomeronasal 2, receptor 31.
Zxdc protein networkhttps://string-db.org/network/10090.ENSMUSP00000074619Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
Smtn protein networkhttps://string-db.org/network/10090.ENSMUSP00000074621Smoothelin; Structural protein of the cytoskeleton.
Trim17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074639E3 ubiquitin-protein ligase TRIM17; May function as a ubiquitin E3 ligase. Belongs to the TRIM/RBCC family.
Actg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074658Actin, gamma-enteric smooth muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic ce [...]
Klk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074659Kallikrein-1; Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin; Belongs to the peptidase S1 family. Kallikrein subfamily.
Kif21b protein networkhttps://string-db.org/network/10090.ENSMUSP00000074661Kinesin-like protein KIF21B; Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neur [...]
Rex1bd protein networkhttps://string-db.org/network/10090.ENSMUSP00000074670Required for excision 1-B domain-containing protein.
Plekha1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074675Pleckstrin homology domain-containing family A member 1; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins t [...]
Cdh11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074681Cadherin-11; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the [...]
Mup14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074696Major urinary protein 12; Belongs to the calycin superfamily. Lipocalin family.
Dsc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074702Desmocollin-2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal [...]
Cdyl protein networkhttps://string-db.org/network/10090.ENSMUSP00000074707Chromodomain Y-like protein; [Isoform 2]: Chromatin reader protein that recognizes and binds histone H3 trimethylated at 'Lys-9', dimethylated at 'Lys-27' and trimethylated at 'Lys-27' (H3K9me3, [...]
Osm protein networkhttps://string-db.org/network/10090.ENSMUSP00000074708Oncostatin-M; Growth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G- CSF and GM-CSF from endothelial cells (By similari [...]
Olfr888 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074713Olfactory receptor MOR162-4.
Hspe1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000007472410 kDa heat shock protein, mitochondrial; Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported pr [...]
Plekhg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074729Pleckstrin homology domain-containing family G member 3.
Cyp4f13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074733Cytochrome P450, family 4, subfamily f, polypeptide 13; Belongs to the cytochrome P450 family.
Zfp874a protein networkhttps://string-db.org/network/10090.ENSMUSP00000074735Regulator of sex-limitation candidate 15.
Pitpnm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074737Membrane-associated phosphatidylinositol transfer protein 3; Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions (By similarity [...]
Defa34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074745Defensin, alpha, 34.
Exosc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074756Exosome complex component CSL4; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrada [...]
Unc5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000074758Netrin receptor UNC5C; Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. NTN1/Netrin-1 binding [...]
St8sia5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074764Alpha-2,8-sialyltransferase 8E; May be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively.
Mrgprh protein networkhttps://string-db.org/network/10090.ENSMUSP00000074768Mas-related G-protein coupled receptor member H; Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity); Belongs to th [...]
Ppargc1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000074771Peroxisome proliferator-activated receptor gamma coactivator 1-beta; Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of es [...]
Hdhd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074775Haloacid dehalogenase-like hydrolase domain-containing 5; Belongs to the HAD-like hydrolase superfamily.
Ttr protein networkhttps://string-db.org/network/10090.ENSMUSP00000074783Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Gria2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074787Glutamate receptor 2; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate [...]
Pdzd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074788PDZ domain-containing 2.
Olfr248 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074799Olfactory receptor.
Orm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074810Alpha-1-acid glycoprotein 2; Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain (By similarity). Appears to function in modulating [...]
Pip protein networkhttps://string-db.org/network/10090.ENSMUSP00000074818Prolactin-inducible protein homolog.
Vpreb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074835Immunoglobulin omega chain; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements i [...]
Pard3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000074837Partitioning defective 3 homolog B; Putative adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions [...]
Gm10147 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074848Predicted gene, ENSMUSG00000073257.
Olfr1287 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074850Olfactory receptor.
Szt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074862KICSTOR complex protein SZT2; As part of the KICSTOR complex functions in the amino acid- sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 [...]
Btbd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074864BTB/POZ domain-containing protein 3; Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopica [...]
Stard5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074872StAR-related lipid transfer protein 5; May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.
Mettl7a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074875Methyltransferase-like 7A3.
Gm10024 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074876Keratin-associated protein 12-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Mab21l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074878Putative nucleotidyltransferase MAB21L1; Required for several aspects of embryonic development including normal development of the eye, notochord, neural tube and other organ tissues, and for emb [...]
Cxcl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074885C-X-C motif chemokine 2; Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst.
Ddn protein networkhttps://string-db.org/network/10090.ENSMUSP00000074895Dendrin; Promotes apoptosis of kidney glomerular podocytes. Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retentio [...]
Nectin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074898Nectin-2; Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell prolife [...]
Nfia protein networkhttps://string-db.org/network/10090.ENSMUSP00000074899Nuclear factor 1 A-type; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These [...]
Cr1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000074902Complement component receptor 1-like protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and [...]
Chic2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074903Cysteine-rich hydrophobic domain-containing protein 2; Belongs to the CHIC family.
Cav3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074922Caveolin-3; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-ga [...]
Btnl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074927Butyrophilin-like 6.
Defb39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074947Beta-defensin 39; Has antibacterial activity.
Safb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074953Scaffold attachment factor B2; Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation (By similarity).
Serpinb9f protein networkhttps://string-db.org/network/10090.ENSMUSP00000074958Serine (Or cysteine) peptidase inhibitor, clade B, member 9f; Belongs to the serpin family.
Brsk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074969Serine/threonine-protein kinase BRSK2; Serine/threonine-protein kinase that plays a key role in polarization of neurons and axonogenesis, cell cycle progress and insulin secretion. Phosphorylates [...]
Mcm9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074978DNA helicase MCM9; Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross- links (ICLs) by homologous recombination (H [...]
Cenph protein networkhttps://string-db.org/network/10090.ENSMUSP00000074988Centromere protein H; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segre [...]
Cyp2a12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074990Cytochrome P450 2A12; Highly active in the 7-alpha-hydroxylation of testosterone.
H3c7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000074994Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones there [...]
Sult2b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075005Sulfotransferase 2B1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Preferentially sulfonates cholesterol. Catalyzes [...]
Abcb10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075011ATP-binding cassette sub-family B member 10, mitochondrial; May mediate critical mitochondrial transport functions related to heme biosynthesis; Belongs to the ABC transporter superfamily. ABCB f [...]
Tnfrsf22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075018Tumor necrosis factor receptor superfamily member 22; Receptor for the cytotoxic ligand TNFSF10/TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects ce [...]
Olfr504 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075025Olfactory receptor Olfr504.
Gm10282 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075031Non-histone chromosomal protein HMG-17; Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which [...]
Glra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075032Glycine receptor subunit alpha-1; Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and bet [...]
Pstk protein networkhttps://string-db.org/network/10090.ENSMUSP00000075037L-seryl-tRNA(Sec) kinase; Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis. No activity with other tRNAs has bee [...]
Ttc41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075059Tetratricopeptide repeat protein 41.
Ptpn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075063Tyrosine-protein phosphatase non-receptor type 3; May act at junctions between the membrane and the cytoskeleton.
Lrmda protein networkhttps://string-db.org/network/10090.ENSMUSP00000075065Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation.
Npm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075067Nucleophosmin; Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppr [...]
Calcr protein networkhttps://string-db.org/network/10090.ENSMUSP00000075070Calcitonin receptor; This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to th [...]
Rnase2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000075074Ribonuclease 2B; This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Possesses a wide variety of biological ac [...]
1700020N15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000075079RIKEN cDNA 1700020N15 gene.
Ap3s2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075082AP-3 complex subunit sigma-2; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral str [...]
Upf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075089Regulator of nonsense transcripts 1; RNA-dependent helicase and ATPase required for nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translatio [...]
Nfatc2ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000075094NFATC2-interacting protein; In T-helper 2 (Th2) cells, regulates the magnitude of NFAT- driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. [...]
Methig1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075098HIG1 domain family member 1C.
Ado protein networkhttps://string-db.org/network/10090.ENSMUSP000000751072-aminoethanethiol dioxygenase.
Yipf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075113Protein YIPF1; Belongs to the YIP1 family.
Cox6b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075150Cytochrome c oxidase subunit 6B1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chai [...]
Olfr212 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075164Olfactory receptor Olfr212.
Abl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075167Tyrosine-protein kinase ABL1; Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extrac [...]
Drd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075170D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family.
Megf10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075174Multiple epidermal growth factor-like domains protein 10; Membrane receptor involved in phagocytosis by macrophages and astrocytes of apoptotic cells. Receptor for C1q, an eat-me signal, that bin [...]
Tubb2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000075178Tubulin beta-2B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha c [...]
Rex2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075179Reduced expression 2.
Fthl17c protein networkhttps://string-db.org/network/10090.ENSMUSP00000075195Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Atp13a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075204Probable cation-transporting ATPase 13A5; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
Nsd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075210Histone-lysine N-methyltransferase NSD2; Histone methyltransferase with histone H3 'Lys-27' (H3K27me) methyltransferase activity forming trimethylated 'Lys-27' (H3K27me3).
Jag2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075224Protein jagged-2; Putative Notch ligand involved in the mediation of Notch signaling. Plays an essential role during limb, craniofacial and thymic development. May be involved in myogenesis and i [...]
Mrpl42 protein networkhttps://string-db.org/network/10090.ENSMUSP0000007522639S ribosomal protein L42, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL42 family.
Cyp3a41b protein networkhttps://string-db.org/network/10090.ENSMUSP00000075234Cytochrome P450 3A41.
A1cf protein networkhttps://string-db.org/network/10090.ENSMUSP00000075235APOBEC1 complementation factor; Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA cod [...]
Adgre5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075240CD97 antigen subunit alpha; Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration.
Olfr1371 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075241Olfactory receptor.
Arhgap35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075242Rho GTPase-activating protein 35; Rho GTPase-activating protein (GAP). Binds several acidic phospholipids which inhibits the Rho GAP activity to promote the Rac GAP activity. This binding is inhi [...]
Cks2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075250Cyclin-dependent kinases regulatory subunit 2; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function; Belongs to the CKS family.
Ugt2b37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075255UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
Fbxo40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075266F-box only protein 40; Probable substrate-recognition component of the SCF (SKP1- CUL1-F-box protein)-type E3 ubiquitin ligase complex that may function in myogenesis.
Mysm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075269Histone H2A deubiquitinase MYSM1; Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a co [...]
Zic2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075283Zinc finger protein ZIC 2; Acts as a transcriptional activator or repressor. Plays important roles in the early stage of organogenesis of the CNS. Activates the transcription of the serotonin tra [...]
Pex19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075289Peroxisomal biogenesis factor 19; Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stab [...]
Tsnax protein networkhttps://string-db.org/network/10090.ENSMUSP00000075290Translin-associated protein X; Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis (By similar [...]
Psg29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075320Pregnancy-specific glycoprotein 29.
Ppp2r3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000075327Protein phosphatase 2, regulatory subunit B'', alpha.
Tdpoz4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075338TD and POZ domain-containing protein 4.
Taf1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000075339TATA box-binding protein-associated factor RNA polymerase I subunit B; Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple st [...]
Mup4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075356Major urinary protein 4; Binds pheromones, likely to displace pheromones complexed to urinary MUPs and transport them to the vomeronasal organ (VNO) where they associate with their neuronal recep [...]
Ldoc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075366Protein LDOC1; May have an important role in the development and/or progression of some cancers.
Pdzrn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075376E3 ubiquitin-protein ligase PDZRN3; E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its en [...]
Cand2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075377Cullin-associated NEDD8-dissociated protein 2; Probable assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate- recognition F-b [...]
Gm12800 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075380Predicted gene 12800.
Olfr1333 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075398Olfactory receptor Olfr1333.
Cntnap5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000075416Contactin-associated protein like 5-3; May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercel [...]
Csf2ra protein networkhttps://string-db.org/network/10090.ENSMUSP00000075423Granulocyte-macrophage colony-stimulating factor receptor subunit alpha; Low affinity receptor for granulocyte-macrophage colony- stimulating factor. Transduces a signal that results in the proli [...]
Bglap protein networkhttps://string-db.org/network/10090.ENSMUSP00000075425Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family.
Prcp protein networkhttps://string-db.org/network/10090.ENSMUSP00000075429Lysosomal Pro-X carboxypeptidase; Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymati [...]
Prp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075435Proline-rich protein 2.
Zcrb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075441Zinc finger CCHC-type and RNA-binding motif-containing protein 1.
Vmn1r53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075455Vomeronasal type-1 receptor 53; Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
Ctf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075459Cardiotrophin-2; Increases the platelet count associated with splenomegaly. May have an important role in neuronal precursor development and maturation.
Pdgfa protein networkhttps://string-db.org/network/10090.ENSMUSP00000075463Platelet-derived growth factor subunit A; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Poten [...]
Rnase11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075472Putative inactive ribonuclease 11.
Tas2r125 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075483Taste receptor type 2 member 125; Putative taste receptor which may play a role in the perception of bitterness.
Zfp58 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075487Zinc finger protein 58; May have a role during differentiation processes. Belongs to the krueppel C2H2-type zinc-finger protein family.
Srrm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075488Serine/arginine repetitive matrix protein 4; Splicing factor specifically required for neural cell differentiation. Acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target [...]
Fnip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075497Folliculin-interacting protein 2; Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client pr [...]
Ackr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075507Atypical chemokine receptor 4; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal [...]
Tas2r124 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075509Taste receptor type 2 member 124; Putative taste receptor which may play a role in the perception of bitterness.
Eno1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000075513Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypox [...]
Mtx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075526Metaxin.
Rnf207 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075540RING finger protein 207; Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export f [...]
Krtap19-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075543Keratin-associated protein 19-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Spink7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075551Serine protease inhibitor Kazal-type 7; Probable serine protease inhibitor.
Zfp935 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075552Zinc finger protein 935.
Abtb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075566Ankyrin repeat and BTB/POZ domain-containing protein 2; May be involved in the initiation of hepatocyte growth.
Pum3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075573Pumilio homolog 3; Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence spe [...]
Rcc1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000075581RCC1-like G exchanging factor-like protein; Guanine nucleotide exchange factor (GEF) for mitochondrial dynamin-related GTPase OPA1. Activates OPA1, by exchanging bound GDP for free GTP, and drive [...]
Carmil3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075587Capping protein, Arp2/3 and myosin-I linker protein 3; Belongs to the CARMIL family.
Ifit3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000075599Interferon-induced protein with tetratricopeptide repeats 3B.
Zfp865 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075601Zinc finger protein 865; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Itgb1bp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075609Integrin beta-1-binding protein 1; Key regulator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alph [...]
Olfr1076 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075612Olfactory receptor 1076.
Zfp512 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075613Zinc finger protein 512; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Upf3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000075614UPF3 regulator of nonsense transcripts homolog B (yeast).
Rabep1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075619Rab GTPase-binding effector protein 1; Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling en [...]
Abca15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075621ATP-binding cassette transporter sub-family A member 15.
Prpf40a protein networkhttps://string-db.org/network/10090.ENSMUSP00000075655Pre-mRNA-processing factor 40 homolog A; Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. Plays a role in the [...]
Arhgap10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075658Rho GTPase-activating protein 10; GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organizat [...]
Phldb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075672Pleckstrin homology-like domain family B member 2; Seems to be involved in the assembly of the postsynaptic apparatus. May play a role in acetyl-choline receptor (AChR) aggregation in the postsyn [...]
Pepd protein networkhttps://string-db.org/network/10090.ENSMUSP00000075683Xaa-Pro dipeptidase; Splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position. Plays an important role in collagen metabolism because of the high level of iminoacids in [...]
Gria3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075687Glutamate receptor 3; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate [...]
Serpinb1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000075690Leukocyte elastase inhibitor A; Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. Acts prim [...]
Tspan7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075692Tetraspanin-7; May be involved in cell proliferation and cell motility; Belongs to the tetraspanin (TM4SF) family.
Sf3b4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075709Splicing factor 3B subunit 4; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U [...]
Csn1s2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000075716Alpha-S2-casein-like A; Important role in the capacity of milk to transport calcium phosphate.
Fbxw11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075721F-box/WD repeat-containing protein 11; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent prot [...]
Ces2f protein networkhttps://string-db.org/network/10090.ENSMUSP00000075722Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
Pmpca protein networkhttps://string-db.org/network/10090.ENSMUSP00000075762Mitochondrial-processing peptidase subunit alpha; Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off [...]
Ggt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075773Glutathione hydrolase 6 heavy chain; Cleaves glutathione conjugates; Belongs to the gamma-glutamyltransferase family.
Gpr155 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075788G protein-coupled receptor 155.
Nlrp4e protein networkhttps://string-db.org/network/10090.ENSMUSP00000075794NACHT, LRR and PYD domains-containing protein 4E; May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound rec [...]
Slc22a21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075814Solute carrier family 22 member 21; Sodium-ion independent, medium affinity carnitine transporter. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodi [...]
Speer2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075821Spermatogenesis-associated glutamate (E)-rich protein 2.
Usp17lb protein networkhttps://string-db.org/network/10090.ENSMUSP00000075822Ubiquitin carboxyl-terminal hydrolase 17-like protein B; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the [...]
Olfr898 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075824Olfactory receptor.
Pyroxd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075825Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase.
Irf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075839Interferon regulatory factor 6; Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal developm [...]
Olfr917 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075857Olfactory receptor.
Tas2r138 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075876Taste receptor type 2 member 38; Putative taste receptor which may play a role in the perception of bitterness; Belongs to the G-protein coupled receptor T2R family.
Sult2a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075884Sulfotransferase; Belongs to the sulfotransferase 1 family.
Ccdc36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075898Interactor of HORMAD1 protein 1; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114 [...]
Crtc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075916CREB-regulated transcription coactivator 1; Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coa [...]
Fbxw19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075918F-box and WD-40 domain protein 19.
Stmnd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075923Stathmin domain-containing protein 1.
Arap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075924Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2; Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase- activating protein that modulates actin cytoskeleton remodel [...]
Zfp280c protein networkhttps://string-db.org/network/10090.ENSMUSP00000075933Zinc finger protein 280C; May function as a transcription factor.
1810009J06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000075935RIKEN cDNA 1810009J06 gene; Belongs to the peptidase S1 family.
Fcgbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000075945Fc fragment of IgG-binding protein.
Ndufa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075953NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved [...]
Etaa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075957Ewing's tumor-associated antigen 1 homolog; Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity. Recruited to stalled [...]
Plppr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075966Phospholipid phosphatase-related protein type 1; Belongs to the PA-phosphatase related phosphoesterase family.
Cldn34b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075967Claudin 34B2.
Slc25a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075987Phosphate carrier protein, mitochondrial; Transport of phosphate groups from the cytosol to mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochond [...]
Sypl protein networkhttps://string-db.org/network/10090.ENSMUSP00000075990Synaptophysin-like protein 1.
Ikzf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000075992DNA-binding protein Ikaros; Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the developm [...]
Ccn6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076003Cellular communication network factor 6; Plays a role in mitochondrial electron transport and mitochondrial respiration.
Slc39a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076012Zinc transporter ZIP1; Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body (By similarity). Belongs to the ZIP transporter (TC 2.A.5) family [...]
Gm1123 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076020CAR-like soluble protein.
Scaf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076024SR-related and CTD-associated factor 8; Anti-terminator protein required to prevent early mRNA termination during transcription. Together with SCAF4, acts by suppressing the use of early, alterna [...]
Dsg1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000076026Desmoglein-1-beta; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Defa21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076041Alpha-defensin 21; May have microbicidal activities; Belongs to the alpha-defensin family.
Tas2r106 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076043Taste receptor type 2 member 106; Putative taste receptor which may play a role in the perception of bitterness.
Defb35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076067Beta-defensin 35; Has antibacterial activity.
Atg13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076081Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the p [...]
Pcdhgc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076085Protocadherin gamma subfamily C, 3.
Iah1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076090Isoamyl acetate-hydrolyzing esterase 1 homolog; Probable lipase.
Utrn protein networkhttps://string-db.org/network/10090.ENSMUSP00000076093Utrophin.
Efna5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076115Ephrin-A5; Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial [...]
Il34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076120Interleukin-34; Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an impor [...]
Olfr345 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076122Olfactory receptor.
Plk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076130Serine/threonine-protein kinase PLK3; Serine/threonine-protein kinase involved in cell cycle regulation, response to stress and Golgi disassembly. Polo-like kinases act by binding and phosphoryla [...]
Zdhhc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076157Palmitoyltransferase ZDHHC6; Endoplasmic reticulum palmitoyl acyltransferase that mediates palmitoylation of proteins such as AMFR, CALX, ITPR1 and TFRC. Palmitoylates calnexin (CALX), which is r [...]
Cop1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076160E3 ubiquitin-protein ligase COP1; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an [...]
Olfr945 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076169Olfactory receptor.
Krtap6-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076172Glycine tyrosine-rich hair keratin protein.
Gpkow protein networkhttps://string-db.org/network/10090.ENSMUSP00000076178G-patch domain and KOW motifs-containing protein; RNA-binding protein involved in pre-mRNA splicing. Belongs to the MOS2 family.
Arl16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076188ADP-ribosylation factor-like 16.
Trim30a protein networkhttps://string-db.org/network/10090.ENSMUSP00000076189Tripartite motif-containing protein 30A; Trans-acting factor that regulates gene expression of interleukin 2 receptor alpha chain. May affect IL2R-alpha expression through cis-acting negative reg [...]
Olfr115 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076203Olfactory receptor 115.
C1qtnf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076206Complement C1q tumor necrosis factor-related protein 7.
Ttf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076208Transcription termination factor 2; DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May [...]
Piwil4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076213Piwi-like protein 4; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the [...]
Gpn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076217GPN-loop GTPase 1; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. Forms an interface between the RNA poly [...]
Spry3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076219Sprouty RTK signaling antagonist 3.
Zdhhc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076224Probable palmitoyltransferase ZDHHC8; Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1; Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 s [...]
Rabac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076227Prenylated Rab acceptor protein 1; General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPas [...]
Sohlh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076253Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1; Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermat [...]
4930453N24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000076255Uncharacterized protein C3orf38 homolog; May be involved in apoptosis regulation.
Ly6m protein networkhttps://string-db.org/network/10090.ENSMUSP00000076264Lymphocyte antigen 6 complex, locus M.
Olfr960 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076315Olfactory receptor MOR224-12.
Tmem151a protein networkhttps://string-db.org/network/10090.ENSMUSP00000076321Transmembrane protein 151A.
Olfr996 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076330Olfactory receptor.
Ptpro protein networkhttps://string-db.org/network/10090.ENSMUSP00000076364Receptor-type tyrosine-protein phosphatase O; Possesses tyrosine phosphatase activity. Plays a role in regulating the glomerular pressure/filtration rate relationship through an effect on podocyt [...]
Gjc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076367Gap junction gamma-3 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a [...]
Sftpd protein networkhttps://string-db.org/network/10090.ENSMUSP00000076383Pulmonary surfactant-associated protein D; Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccha [...]
Dsg1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000076393Desmoglein-1-alpha; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
H2bu2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076397Histone H2B type 3-A; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
Dppa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076416Developmental pluripotency-associated 1.
Polr3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000076418DNA-directed RNA polymerase III subunit RPC2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest co [...]
Ethe1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076433Persulfide dioxygenase ETHE1, mitochondrial; First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcripti [...]
Tpte protein networkhttps://string-db.org/network/10090.ENSMUSP00000076435Transmembrane phosphatase with tensin homology.
Krt80 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076437Keratin, type II cytoskeletal 80; Belongs to the intermediate filament family.
Olfr304 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076449Olfactory receptor.
Gtpbp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076458Putative GTP-binding protein 6.
Sgcd protein networkhttps://string-db.org/network/10090.ENSMUSP00000076459Delta-sarcoglycan; Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Dhrsx protein networkhttps://string-db.org/network/10090.ENSMUSP00000076472Dehydrogenase/reductase SDR family member on chromosome X homolog; Involved in the positive regulation of starvation-induced autophagy.
Olfr1337 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076483Olfactory receptor 1337.
Rxra protein networkhttps://string-db.org/network/10090.ENSMUSP00000076491Retinoic acid receptor RXR-alpha; Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (RARs) and binds to target response elem [...]
Gfm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076503Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from t [...]
Ext1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076505Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Requ [...]
Atrnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076514Attractin-like protein 1; May play a role in melanocortin signaling pathways that regulate energy homeostasis.
Pdia4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076521Protein disulfide-isomerase A4.
Ptpra protein networkhttps://string-db.org/network/10090.ENSMUSP00000076533Receptor-type tyrosine-protein phosphatase alpha; Tyrosine protein phosphatase which is involved in integrin- mediated focal adhesion formation. Following integrin engagement, specifically recrui [...]
Irx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076562Iroquois-class homeodomain protein IRX-1.
Dmac2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076563Distal membrane-arm assembly complex protein 2; Required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of [...]
Rnpep protein networkhttps://string-db.org/network/10090.ENSMUSP00000076564Aminopeptidase B; Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin a [...]
Olfr850 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076569Olfactory receptor.
Hmbs protein networkhttps://string-db.org/network/10090.ENSMUSP00000076575Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps; Belongs to the HMBS family.
Klk1b4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076576Kallikrein 1-related peptidase-like b4.
Cyp2b23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076578Cytochrome P450, family 2, subfamily b, polypeptide 23; Belongs to the cytochrome P450 family.
2810006K23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000076594Probable peptide chain release factor C12orf65 homolog, mitochondrial; May act as a codon-independent translation release factor that has lost all stop codon specificity and directs the terminati [...]
Bloc1s3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076624Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as plat [...]
Defa38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076665Defensin, alpha, 38.
Dapk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076666Death-associated protein kinase 1; Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regu [...]
Olfr763 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076671Olfactory receptor.
Olfr1136 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076681Olfactory receptor.
Chst15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076682Carbohydrate sulfotransferase 15; Sulfotransferase that transfers sulfate from 3'- phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroit [...]
Stk19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076686Serine/threonine-protein kinase 19; Serine/threonine-protein kinase that acts as a key regulator of NRAS signaling by mediating phosphorylation of NRAS at 'Ser-89', thereby enhancing NRAS-binding [...]
Zfp953 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076700Zinc finger protein 953.
Dqx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076708ATP-dependent RNA helicase DQX1.
Tmem236 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076722Transmembrane protein 236.
Mab21l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076729Protein mab-21-like 2; Required for several aspects of embryonic development including normal development of the eye, notochord, neural tube and other organ tissues, and for embryonic turning. Be [...]
Klk1b22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076733Kallikrein 1-related peptidase b22; Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin; Belongs to the peptidase S1 family. Kallikrein subfamily.
Rdh19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076735Retinol dehydrogenase 19; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Cttnbp2nl protein networkhttps://string-db.org/network/10090.ENSMUSP00000076751CTTNBP2 N-terminal-like protein.
Prss43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076752Putative inactive serine protease 43; Plays a role in spermatogenesis. Involved in germ cell survival during meiosis; Belongs to the peptidase S1 family.
Tuba1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000076777Detyrosinated tubulin alpha-1B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site [...]
Porcn protein networkhttps://string-db.org/network/10090.ENSMUSP00000076790Protein-serine O-palmitoleoyltransferase porcupine; Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, [...]
Pigu protein networkhttps://string-db.org/network/10090.ENSMUSP00000076816Phosphatidylinositol glycan anchor biosynthesis class U protein; Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid por [...]
Cyp4f37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076827Cytochrome P450, family 4, subfamily f, polypeptide 37; Belongs to the cytochrome P450 family.
Atp10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000076844Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
Obp2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000076851Odorant-binding protein 2a; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis.
Col4a3bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000076856Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicula [...]
Tfe3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076864Transcription factor E3; Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TF [...]
Ccdc148 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076871Coiled-coil domain-containing protein 148.
Calml3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076880Calmodulin-like protein 3; May function as a specific light chain of unconventional myosin-10 (MYO10), also enhances MYO10 translation, possibly by acting as a chaperone for the emerging MYO10 he [...]
Lyzl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076887Lysozyme-like protein 4; May be involved in fertilization. Has no detectable bacteriolytic in vitro. Has no lysozyme activity in vitro (By similarity).
Tmem268 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076891Transmembrane protein 268.
Krtap19-9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000076896Keratin-associated protein 19-9b; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), whic [...]
Mup21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076899Major urinary protein 21; Belongs to the calycin superfamily. Lipocalin family.
Pik3c2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000076911Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.
Slc9a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076922Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
Arpc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076933Actin-related protein 2/3 complex subunit 5; Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The [...]
Olfr44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076935Olfactory receptor.
Sag protein networkhttps://string-db.org/network/10090.ENSMUSP00000076948S-arrestin; Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO. May play a role in preventing li [...]
Zfp61 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076954Zinc finger protein 61.
Tnfaip8l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076961Tumor necrosis factor alpha-induced protein 8-like protein 1; Acts as a negative regulator of mTOR activity.
Zfp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076964Zinc finger protein 1; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Ssrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076971FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a [...]
Hnrnph1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000076989Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the [...]
Prpf4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000077019Serine/threonine-protein kinase PRP4 homolog; Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
Cyp2b19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077021Cytochrome P450 2B19; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a va [...]
Vps13c protein networkhttps://string-db.org/network/10090.ENSMUSP00000077040Vacuolar protein sorting-associated protein 13C; Necessary for proper mitochondrial function and maintenance of mitochondrial transmembrane potential. Involved in the regulation of PINK1/PRKN-med [...]
St5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077067DENN domain-containing protein 2B; [Isoform 1]: May be involved in cytoskeletal organization and tumorogenicity. Seems to be involved in a signaling transduction pathway leading to activation of [...]
Cfi protein networkhttps://string-db.org/network/10090.ENSMUSP00000077074Complement factor I heavy chain; Trypsin-like serine protease that plays an essential role in regulating the immune response by controlling all complement pathways. Inhibits these pathways by cle [...]
Unc5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000077080Netrin receptor UNC5B; Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in gro [...]
Haghl protein networkhttps://string-db.org/network/10090.ENSMUSP00000077091Hydroxyacylglutathione hydrolase-like protein; Hydrolase acting on ester bonds.
Dock10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077099Dedicator of cytokinesis protein 10; Guanine nucleotide-exchange factor (GEF) that activates CDC42 and RAC1 by exchanging bound GDP for free GTP. Essential for dendritic spine morphogenesis in Pu [...]
Sgcg protein networkhttps://string-db.org/network/10090.ENSMUSP00000077106Gamma-sarcoglycan; Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Ccdc102a protein networkhttps://string-db.org/network/10090.ENSMUSP00000077107Coiled-coil domain-containing protein 102A.
Vmn2r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077109Vomeronasal 2, receptor 2.
Kcng2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077112Potassium voltage-gated channel, subfamily G, member 2; Belongs to the potassium channel family.
Fam71d protein networkhttps://string-db.org/network/10090.ENSMUSP00000077119Family with sequence similarity 71, member D.
Osbpl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077123Oxysterol-binding protein-related protein 6; Regulates cellular transport and efflux of cholesterol (By similarity). Plays a role in phosphatidylinositol-4-phophate (PI4P) turnover at the neurona [...]
Itga1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077132Integrin alpha-1; Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negativ [...]
Gpbar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077135G-protein coupled bile acid receptor 1; Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP productio [...]
Mettl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077138tRNA N(3)-methylcytidine methyltransferase METTL6; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of t [...]
Tmc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077139Transmembrane channel-like protein 2; Probable ion channel required for the normal function of cochlear hair cells (By similarity). Component of the hair cell's mechanotransduction (MET) machiner [...]
Tex101 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077150Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct probably through molecule adhesion ADAM [...]
Glmn protein networkhttps://string-db.org/network/10090.ENSMUSP00000077168Glomulin; Regulatory component of cullin-RING-based SCF (SKP1-Cullin-F- box protein) E3 ubiquitin-protein ligase complexes. Inhibits E3 ubiquitin ligase activity by binding to the RING domain of [...]
Ipcef1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077215Interactor protein for cytohesin exchange factors 1; Enhances the promotion of guanine-nucleotide exchange by PSCD2 on ARF6 in a concentration-dependent manner.
Tank protein networkhttps://string-db.org/network/10090.ENSMUSP00000077219TRAF family member-associated NF-kappa-B activator; Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immu [...]
Eif1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000077223Eukaryotic translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiato [...]
Rsrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077226Arginine/serine-rich protein 1; Belongs to the RSRP family.
Mllt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077232Protein AF-9; Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausi [...]
Defa35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077259Alpha-defensin 5; Probably contributes to the antimicrobial barrier function of the small bowel mucosa; Belongs to the alpha-defensin family.
Cfl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077262Cofilin-2; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major co [...]
Asph protein networkhttps://string-db.org/network/10090.ENSMUSP00000077273Aspartyl/asparaginyl beta-hydroxylase; [Isoform 1]: specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins; Belongs to the a [...]
Olfr503 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077296Olfactory receptor Olfr503.
Dynlrb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077301Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and [...]
Gng8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077314Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling sy [...]
Magea1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077323Melanoma antigen, family A, 1.
Serhl protein networkhttps://string-db.org/network/10090.ENSMUSP00000077345Serine hydrolase-like protein; Probable serine hydrolase. May be related to cell muscle hypertrophy.
Pou3f4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077354POU domain, class 3, transcription factor 4; Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature [...]
Nsl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077380Kinetochore-associated protein NSL1 homolog; Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis.
Olfr1373 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077384Olfactory receptor.
Pcdhb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077389Protocadherin beta 5.
Gm4787 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077390Predicted gene, EG214321.
Olfr926 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077405Olfactory receptor.
Lyg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077422Lysozyme g-like protein 2; May act as a potent antibacterial protein that may play a role in the innate immunity; Belongs to the glycosyl hydrolase 23 family.
Rasal2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077423RAS protein activator-like 2.
Slc22a16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077428Solute carrier family 22 member 16; High affinity carnitine transporter; the uptake is partially sodium-ion dependent. Thought to mediate the L-carnitine secretion mechanism from testis epididyma [...]
Cacnb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077438Voltage-dependent L-type calcium channel subunit beta-4; The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium curre [...]
Mff protein networkhttps://string-db.org/network/10090.ENSMUSP00000077446Mitochondrial fission factor; Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mito [...]
Csgalnact1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077459Chondroitin sulfate N-acetylgalactosaminyltransferase 1; Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of [...]
Emp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077466Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell mi [...]
Vrk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077471Serine/threonine-protein kinase VRK2; Serine/threonine kinase that regulates several signal transduction pathways. Isoform 1 modulates the stress response to hypoxia and cytokines, such as interl [...]
Ifnl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077473Interferon lambda-3; Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a l [...]
H2ac4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077477Histone H2A type 1-B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
Slitrk6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077492SLIT and NTRK-like protein 6; Regulator of neurite outgrowth required for normal hearing and vision.
Pcbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077509Poly(rC)-binding protein 2; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates [...]
Trim61 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077513Tripartite motif-containing 61.
Olfr1355 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077517Olfactory receptor.
Krtap21-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077524Keratin-associated protein 21-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Ppp3cc protein networkhttps://string-db.org/network/10090.ENSMUSP00000077532Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform; Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracel [...]
Trim31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077535E3 ubiquitin-protein ligase TRIM31; May have E3 ubiquitin-protein ligase activity (By similarity). Regulator of Src-induced anchorage independent cell growth.
Lrrc51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077543Leucine-rich repeat-containing protein 51.
Pirb protein networkhttps://string-db.org/network/10090.ENSMUSP00000077546Leukocyte immunoglobulin-like receptor subfamily B member 3; May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the [...]
Gm14781 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077562Predicted gene 14781.
Kcnh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077563Potassium voltage-gated channel subfamily H member 1; Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel. Channel properties are modulated by subunit assembly. Me [...]
BC048507 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077564Dynein light chain.
Vmn1r64 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077568Vomeronasal type-1 receptor.
Dchs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077574Protocadherin-16; Calcium-dependent cell-adhesion protein. Mediates functions in neuroprogenitor cell proliferation and differentiation. In the heart, has a critical role for proper morphogenesis [...]
Rag1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077584V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assem [...]
Cacna1h protein networkhttps://string-db.org/network/10090.ENSMUSP00000077586Voltage-dependent T-type calcium channel subunit alpha-1H; Voltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activat [...]
Rtn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077594Reticulon-1; May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells.
Sp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077596Transcription factor Sp7; Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences. Belongs to the Sp1 C2H2-ty [...]
Dyrk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077606Dual specificity tyrosine-phosphorylation-regulated kinase 4; Possible non-essential role in spermiogenesis.
Rnf150 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077610RING finger protein 150.
Rxfp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077611Relaxin receptor 1; Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may a [...]
C1qbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000077612Complement component 1 Q subcomponent-binding protein, mitochondrial; Is believed to be a multifunctional and multicompartmental protein involved in inflammation and infection processes, ribosome [...]
Olfr951 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077615Odorant receptor K4h17.
Taar7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000077616Trace amine-associated receptor 7a; Orphan olfactory receptor specific for trace amines. Belongs to the G-protein coupled receptor 1 family.
Sec22c protein networkhttps://string-db.org/network/10090.ENSMUSP00000077628Vesicle-trafficking protein SEC22c; May be involved in vesicle transport between the ER and the Golgi complex; Belongs to the synaptobrevin family.
Clec4b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077636Dendritic cell immuno-activating receptor alpha isoform.
Slc9b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077644Sodium/hydrogen exchanger 9B1; Sperm-specific Na(+)/H(+) exchanger involved in intracellular pH regulation of spermatozoa. Involved in sperm motility and fertility.
Xlr5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000077650X-linked lymphocyte-regulated 5A.
Olfr294 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077662Olfactory receptor.
Tcp11x2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077676T-complex 11 family, X-linked 2.
BC051142 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077685Testis specific basic protein.
Aldoart1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077687Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.
Cryba1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077693Beta-crystallin A1; Crystallins are the dominant structural components of the vertebrate eye lens.
Gadl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077694Acidic amino acid decarboxylase GADL1; Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L- alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respec [...]
Trank1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077697TPR and ankyrin repeat-containing protein 1.
Rab43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077716Ras-related protein Rab-43; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle bet [...]
Dhps protein networkhttps://string-db.org/network/10090.ENSMUSP00000077733Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical ly [...]
Samd12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077741Sterile alpha motif domain-containing protein 12.
Uqcrh protein networkhttps://string-db.org/network/10090.ENSMUSP00000077744Cytochrome b-c1 complex subunit 6, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport [...]
Gid8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077753Glucose-induced degradation protein 8 homolog; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequ [...]
Bak1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077757Bcl-2 homologous antagonist/killer; In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2.
Ppp1r1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000077760Protein phosphatase 1 regulatory subunit 1B; Inhibitor of protein-phosphatase 1.
Gm13078 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077761Predicted gene 13078.
Olfr671 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077774Olfactory receptor.
Lrrc58 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077779Leucine-rich repeat-containing protein 58.
Enah protein networkhttps://string-db.org/network/10090.ENSMUSP00000077781Protein enabled homolog; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellip [...]
Slc10a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077808Sodium/bile acid cotransporter 5.
Casc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077811Protein CASC4; Belongs to the GOLM1/CASC4 family.
H2ac18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077814Histone H2A type 2-A; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
Ms4a19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077828Membrane-spanning 4-domains, subfamily A, member 19.
Xlr4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000077831X-linked lymphocyte-regulated 4A.
Lilrb4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000077833Leukocyte immunoglobulin-like receptor subfamily B member 4; Receptor for class I MHC antigens. Involved in the down- regulation of the immune response and the development of tolerance. Interfere [...]
Vps28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077856Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex, a regulator of vesicular trafficking process; Belongs to the VPS28 family.
9130023H24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000077867RIKEN cDNA 9130023H24 gene.
Fcgr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077873Low affinity immunoglobulin gamma Fc region receptor IV; Receptor for the Fc region of immunoglobulin gamma. Also acts as a receptor for the Fc region of immunoglobulin epsilon. Binds with interm [...]
Il15ra protein networkhttps://string-db.org/network/10090.ENSMUSP00000077878Soluble interleukin-15 receptor subunit alpha; High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG- [...]
Klk1b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077879Kallikrein 1-related peptidase b1; Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin; Belongs to the peptidase S1 family. Kallikrein subfamily.
Tom1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077891Target of Myb protein 1; May be involved in intracellular trafficking. Probable association with membranes.
Kl protein networkhttps://string-db.org/network/10090.ENSMUSP00000077899Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as [...]
Olfr830 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077903Olfactory receptor.
Serpina1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000077909Alpha-1-antitrypsin 1-4; Inhibitor of serine proteases. Can inhibit trypsin and chymotrypsin; relatively ineffective against elastase. Belongs to the serpin family.
Defb50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077918Beta-defensin 50; Has bactericidal activity.
Sorcs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077919VPS10 domain-containing receptor SorCS3.
Ampd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077946AMP deaminase 2; AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle (By similarity); Belo [...]
Phf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077971PHD finger protein 6; Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.
Grsf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077972G-rich sequence factor 1; Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. Binds RNAs c [...]
Olfr376 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077977Olfactory receptor.
Dennd6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000077978Protein DENND6B; Guanine nucleotide exchange factor (GEF) for RAB14. Also has some, lesser GEF activity towards RAB35 (By similarity); Belongs to the DENND6 family.
Kifc5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000077984Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Olfr539 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077990Olfactory receptor.
G6pc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077995Glucose-6-phosphatase 3; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex [...]
Zfp706 protein networkhttps://string-db.org/network/10090.ENSMUSP00000077996Zinc finger protein 706; Transcription repressor involved in the exit of embryonic stem cells (ESCs) from self-renewal. Acts by repressing expression of KLF4.
Tdrd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078022ATP-dependent RNA helicase TDRD9; ATP-binding RNA helicase which plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essent [...]
Bloc1s2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078042Biogenesis of lysosome-related organelles complex 1 subunit 2; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as plat [...]
Tas2r113 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078044Taste receptor type 2 member 113; Putative taste receptor which may play a role in the perception of bitterness.
Hhip protein networkhttps://string-db.org/network/10090.ENSMUSP00000078047Hedgehog-interacting protein; Modulates hedgehog signaling in several cell types, including brain and lung through direct interaction with members of the hedgehog family. Soluble forms inhibit Sh [...]
Slc35e3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078050Solute carrier family 35 member E3; Putative transporter; Belongs to the TPT transporter family. SLC35E subfamily.
Sox11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078070Transcription factor SOX-11; Transcriptional factor involved in the embryonic neurogenesis. May also have a role in tissue modeling during development.
Tmem220 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078084Transmembrane protein 220.
Mapk7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078087Mitogen-activated protein kinase 7; Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. [...]
Aqp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078088Aquaporin-4; Forms a water-specific channel. Plays an important role in brain water homeostasis and in glymphatic solute transport. Required for a normal rate of water exchange across the blood b [...]
Homer1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078093Homer protein homolog 1; Postsynaptic density scaffolding protein. Binds and cross- links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 [...]
Vmn1r240 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078103Vomeronasal type-1 receptor.
Mrpl18 protein networkhttps://string-db.org/network/10090.ENSMUSP0000007812339S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperon [...]
AY358078 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078129cDNA sequence AY358078.
Nmral1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078132NmrA-like family domain-containing protein 1; Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NAD [...]
Chia1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078134Acidic mammalian chitinase; Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune respons [...]
Taar2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078137Trace amine-associated receptor 2; Orphan olfactory receptor specific for trace amines. Belongs to the G-protein coupled receptor 1 family.
H2-Q2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078138Histocompatibility 2, Q region locus 2; Belongs to the MHC class I family.
Ttc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078148Tetratricopeptide repeat protein 8; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is requ [...]
Abcc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078158Multidrug resistance-associated protein 5; Acts as a multispecific organic anion pump which can transport nucleotide analogs; Belongs to the ABC transporter superfamily. ABCC family. Conjugate tr [...]
Letm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078160LETM1 domain-containing protein LETM2, mitochondrial.
Vmn2r10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078162Vomeronasal 2, receptor 10.
Plekhb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078175Pleckstrin homology domain-containing family B member 1.
Stfa2l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078181Stefin-2; This is an intracellular thiol proteinase inhibitor.
Stox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078190Storkhead-box protein 2.
Rph3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000078198Rabphilin-3A; Plays an essential role in docking and fusion steps of regulated exocytosis (By similarity). At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane i [...]
Chpf protein networkhttps://string-db.org/network/10090.ENSMUSP00000078199Chondroitin sulfate synthase 2; Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosam [...]
Vmn2r93 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078200Vomeronasal 2, receptor 93.
Prpf38a protein networkhttps://string-db.org/network/10090.ENSMUSP00000078207Pre-mRNA-splicing factor 38A; Involved in pre-mRNA splicing as a component of the spliceosome; Belongs to the PRP38 family.
Fggy protein networkhttps://string-db.org/network/10090.ENSMUSP00000078216FGGY carbohydrate kinase domain-containing protein.
H2bc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078239H2B clustered histone 8.
Numbl protein networkhttps://string-db.org/network/10090.ENSMUSP00000078245Numb-like protein; Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing [...]
Cyp3a57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078251Cytochrome P450, family 3, subfamily a, polypeptide 57.
Nrsn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078260Neurensin-2; May play a role in maintenance and/or transport of vesicles. Belongs to the VMP family.
S100a7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000078268Protein S100-A15A; Belongs to the S-100 family.
Nme5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078269Nucleoside diphosphate kinase homolog 5; Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes includi [...]
Olfr1032 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078279Olfactory receptor.
Arhgef26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078281Rho guanine nucleotide exchange factor (GEF) 26.
Lypd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078287Ly6/PLAUR domain-containing protein 4.
Mctp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078302Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family.
Ubl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078303Ubiquitin-like protein 3.
Usp17lc protein networkhttps://string-db.org/network/10090.ENSMUSP00000078323Ubiquitin carboxyl-terminal hydrolase 17-like protein C; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Important for p [...]
Ablim1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078336Actin-binding LIM protein 1; May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance.
Apc protein networkhttps://string-db.org/network/10090.ENSMUSP00000078337Adenomatous polyposis coli protein; Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphory [...]
Adam1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000078343Disintegrin and metalloproteinase domain-containing protein 1b; May play a role in spermatogenesis and sperm maturation.
Clec4a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078351C-type lectin domain family 4, member a4.
Lin28b protein networkhttps://string-db.org/network/10090.ENSMUSP00000078361Protein lin-28 homolog B; Suppressor of microRNA (miRNA) biogenesis, including that of let-7 and possibly of miR107, miR-143 and miR-200c. Binds primary let-7 transcripts (pri-let-7), including p [...]
Aspg protein networkhttps://string-db.org/network/10090.ENSMUSP000000783691-alkyl-2-acetylglycerophosphocholine esterase; Exhibits lysophospholipase, transacylase, PAF acetylhydrolase and asparaginase activities (By similarity). Can catalyze three types of transacylati [...]
Pgghg protein networkhttps://string-db.org/network/10090.ENSMUSP00000078372Protein-glucosylgalactosylhydroxylysine glucosidase; Catalyzes the hydrolysis of glucose from the disaccharide unit linked to hydroxylysine residues of collagen and collagen-like proteins.
Zfp239 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078374Zinc finger protein 239; May be involved in transcriptional regulation.
Cep89 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078383Centrosomal protein of 89 kDa; Required for ciliogenesis. Also plays a role in mitochondrial metabolism where it may modulate complex IV activity (By similarity).
Ttyh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078384Protein tweety homolog 1; Probable chloride channel. May be involved in cell adhesion (By similarity); Belongs to the tweety family.
Fam57b protein networkhttps://string-db.org/network/10090.ENSMUSP00000078392Ceramide synthase; Involved in ceramide synthesis. In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides [...]
Tmem91 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078407Transmembrane protein 91.
Speer4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000078415Spermatogenesis-associated glutamate (E)-rich protein 4A.
Wdr90 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078426WD repeat-containing protein 90; Required for efficient primary cilium formation.
Nuggc protein networkhttps://string-db.org/network/10090.ENSMUSP00000078434Nuclear GTPase SLIP-GC; Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA (By similarity). Reduces somatic hypermut [...]
Aadat protein networkhttps://string-db.org/network/10090.ENSMUSP00000078436Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. [...]
Nap1l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078453Nucleosome assembly protein 1-like 3; Belongs to the nucleosome assembly protein (NAP) family.
Sez6l protein networkhttps://string-db.org/network/10090.ENSMUSP00000078454Seizure 6-like protein; Candidate tumor suppressor gene. May contribute to specialized endoplasmic reticulum functions in neurons.
Ube2s protein networkhttps://string-db.org/network/10090.ENSMUSP00000078459Ubiquitin-conjugating enzyme E2 S; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes 'Lys-11'-linked polyubiquitination. Acts as an essentia [...]
Defa17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078485Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.
Rad51b protein networkhttps://string-db.org/network/10090.ENSMUSP00000078490DNA repair protein RAD51 homolog 2; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. M [...]
St6galnac2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078501Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; Catalyzes the transfer of N-acetylneuraminyl groups onto glycan chains in glycoproteins.
Fbxw20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078503F-box and WD-40 domain protein 12.
Vmn1r32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078536Vomeronasal type-1 receptor.
Myo1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000078540Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Paqr9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078547Membrane progesterone receptor epsilon; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(s) mediated pathway. May be involved in regulating rapid P4 sign [...]
Etv5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078551ETS translocation variant 5; Binds to DNA sequences containing the consensus nucleotide core sequence 5'-GGAA.-3'; Belongs to the ETS family.
Frg2f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078560FSHD region gene 2 family member 1.
Tor3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000078572Torsin-3A.
Cldn24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078584Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
Zfp119a protein networkhttps://string-db.org/network/10090.ENSMUSP00000078587KRAB zinc finger protein.
Ybx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078589Y-box-binding protein 1; DNA- and RNA-binding protein involved in various processes, such as translational repression, RNA stabilization, mRNA splicing, DNA repair and transcription regulation. P [...]
1190007I07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000078593Uncharacterized protein C12orf73 homolog.
Sox7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078597Transcription factor SOX-7; Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further diffe [...]
U2surp protein networkhttps://string-db.org/network/10090.ENSMUSP00000078602U2 snRNP-associated SURP motif-containing protein.
Olfr862 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078603Olfactory receptor.
Cyb5d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078623Neuferricin; Heme-binding protein which promotes neuronal but not astrocyte differentiation.
Gss protein networkhttps://string-db.org/network/10090.ENSMUSP00000078630Glutathione synthetase; Belongs to the eukaryotic GSH synthase family.
Gpatch1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078632G patch domain-containing protein 1; Belongs to the GPATCH1 family.
Mup7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078636Novel member of the major urinary protein (Mup) gene family; Belongs to the calycin superfamily. Lipocalin family.
Nsmce2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078641E3 SUMO-protein ligase NSE2; E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required fo [...]
En1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078659Homeobox protein engrailed-1.
Hax1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078661HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. [...]
Ccdc192 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078674Coiled-coil domain-containing 192.
Ctbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078682C-terminal-binding protein 1; Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and [...]
Zfp422 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078685Zinc finger protein 22; Binds DNA through the consensus sequence 5'-CAATG-3'. May be involved in transcriptional regulation and may play a role in tooth formation; Belongs to the krueppel C2H2-ty [...]
Cpeb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078690Cytoplasmic polyadenylation element-binding protein 3; Sequence-specific RNA-binding protein which acts as a translational repressor in the basal unstimulated state but, following neuronal stimul [...]
Gm5591 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078695Predicted gene 5591.
Wdr83os protein networkhttps://string-db.org/network/10090.ENSMUSP00000078697Protein Asterix.
Tnfrsf11b protein networkhttps://string-db.org/network/10090.ENSMUSP00000078705Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts [...]
Csnk1g2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078706Casein kinase I isoform gamma-2; Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It c [...]
Myl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078715Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium.
Mkx protein networkhttps://string-db.org/network/10090.ENSMUSP00000078718Homeobox protein Mohawk; May act as a morphogenetic regulator of cell adhesion. Participates in the early events that lead to differentiation.
Pcyt1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000078721Choline-phosphate cytidylyltransferase A; Controls phosphatidylcholine synthesis; Belongs to the cytidylyltransferase family.
Pth protein networkhttps://string-db.org/network/10090.ENSMUSP00000078723Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.
Gm10058 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078727Predicted gene 10058.
Olfr890 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078733Olfactory receptor Olfr890.
Ugt2a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078740UDP-glucuronosyltransferase 2A2; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
Notch2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078741Neurogenic locus notch homolog protein 2; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand a [...]
Stk24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078746Serine/threonine-protein kinase 24 12 kDa subunit; Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase [...]
Gpr84 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078753G-protein coupled receptor 84; Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the [...]
Ntrk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078757BDNF/NT-3 growth factors receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, [...]
Hsf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078761Heat shock factor protein 2; DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unl [...]
Klk1b27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078786Kallikrein 1-related peptidase b27; Serine protease with chymotrypsin-like cleavage specificity. Shows activity towards casein, gelatin, IGFBP3 and fibronectin but not towards laminin or collagen [...]
Magea3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078793Melanoma antigen, family A, 3.
Znrf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078795E3 ubiquitin-protein ligase ZNRF2; May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiq [...]
Zfp398 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078806Zinc finger protein 398.
Scamp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078808Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family.
Olfr171 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078814Olfactory receptor.
Phex protein networkhttps://string-db.org/network/10090.ENSMUSP00000078863Phosphate-regulating neutral endopeptidase PHEX; Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological act [...]
Ewsr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078867RNA-binding protein EWS; Might function as a transcriptional repressor.
H2al1o protein networkhttps://string-db.org/network/10090.ENSMUSP00000078870Histone H2A; Belongs to the histone H2A family.
Fcer1g protein networkhttps://string-db.org/network/10090.ENSMUSP00000078875High affinity immunoglobulin epsilon receptor subunit gamma; Adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various im [...]
Hspbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078886Hsp70-binding protein 1; Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination media [...]
Las1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000078901Ribosomal biogenesis protein LAS1L; Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA (By similarity). Functions as a component of the Five Friends [...]
Zfand2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000078910AN1-type zinc finger protein 2A.
Ufc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078914Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage; Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
Olfr507 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078926Olfactory receptor 507; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
H2-T22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078927Histocompatibility 2, T region locus 22; Belongs to the MHC class I family.
Gspt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078940Eukaryotic peptide chain release factor GTP-binding subunit ERF3A; Involved in translation termination in response to the termination codons UAA, UAG and UGA (By similarity). Stimulates the activ [...]
Htt protein networkhttps://string-db.org/network/10090.ENSMUSP00000078945Huntingtin, myristoylated N-terminal fragment; [Huntingtin]: May play a role in microtubule-mediated transport or vesicle function.
Egln2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078966Egl nine homolog 2; Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydrox [...]
Slc27a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078971Long-chain fatty acid transport protein 4; Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intes [...]
Slc4a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078972Anion exchange protein 2; Plasma membrane anion exchange protein of wide distribution; Belongs to the anion exchanger (TC 2.A.31) family.
4930595M18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000078984RIKEN cDNA 4930595M18 gene.
Krit1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078985Krev interaction trapped protein 1; Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. Negative regulator of angiogenesis. Inhibits e [...]
Aifm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000078998Ferroptosis suppressor protein 1; A NAD(P)H-dependent oxidoreductase involved in cellular oxidative stress response. At the plasma membrane, catalyzes reduction of coenzyme Q/ubiquinone-10 to ubi [...]
Olfr493 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079005Olfactory receptor 493; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Aldoart2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079022Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.
Rnase1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079025Ribonuclease pancreatic; Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double- stranded RNA (By similarity); Belongs to the [...]
4921509C19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000079030Sperm motility kinase X; May play a role in sperm motility, especially in the regulation of flagellar function.
Adam26b protein networkhttps://string-db.org/network/10090.ENSMUSP00000079032A disintegrin and metallopeptidase domain 26B.
Tmem117 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079038Transmembrane protein 117; Involved in endoplasmic reticulum (ER) stress-induced cell death pathway; Belongs to the TMEM117 family.
Adamts16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079041A disintegrin and metalloproteinase with thrombospondin motifs 16.
Olfr1490 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079057Olfactory receptor.
Olfr292 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079060Olfactory receptor 292.
Cyp2c50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079065Cytochrome P450 2C50; Metabolizes arachidonic acid to several midchain and omega- terminal hydroxyeicosatetraenoic acids (HETE).
Pabpc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079070Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
Sirt7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079093NAD-dependent protein deacetylase sirtuin-7; NAD-dependent protein-lysine deacylase that can act both as a deacetylase or deacylase (desuccinylase, depropionylase and deglutarylase), depending on [...]
Sp140 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079095Sp140 nuclear body protein.
Epb41l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079098Band 4.1-like protein 3, N-terminally processed; Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N- methyltransferases, includ [...]
Slc1a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079100Excitatory amino acid transporter 2; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter [...]
Klk11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079101Kallikrein-11; Possible multifunctional protease. Efficiently cleaves 'bz- Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsi [...]
Ppm1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000079107Protein phosphatase 1B; Enzyme with a broad specificity. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important ro [...]
Birc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079124Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex ( [...]
Zfp947 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079137Predicted gene, EG210853.
Vmn1r216 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079139Vomeronasal type-1 receptor.
Btnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079140Butyrophilin-like protein 1.
Rpl15 protein networkhttps://string-db.org/network/10090.ENSMUSP0000007916360S ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.
Cd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079172T-cell differentiation antigen CD6; Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166. Contributes to signaling cascades [...]
Yaf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079179YY1-associated factor 2; Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysi [...]
Rps25 protein networkhttps://string-db.org/network/10090.ENSMUSP0000007918040S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.
Oas1a protein networkhttps://string-db.org/network/10090.ENSMUSP000000791982'-5'-oligoadenylate synthase 1A; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in o [...]
DXBay18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079200Predicted gene, OTTMUSG00000017677.
Olfr954 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079205Olfactory receptor.
Cfap299 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079208Cilia- and flagella-associated protein 299; May be involved in spermatogenesis.
Col25a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079210Collagen-like Alzheimer amyloid plaque component; Inhibits fibrillization of amyloid-beta peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resist [...]
Zfp551 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079222Zinc finger protein 551; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Ing2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079226Inhibitor of growth protein 2; Seems to be involved in p53/TP53 activation and p53/TP53- dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like co [...]
Snrpa protein networkhttps://string-db.org/network/10090.ENSMUSP00000079228U1 small nuclear ribonucleoprotein A; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 [...]
Rest protein networkhttps://string-db.org/network/10090.ENSMUSP00000079231RE1-silencing transcription factor; Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the [...]
Akr1c20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079232Aldo-keto reductase family 1, member C20.
Atp8a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079238Phospholipid-transporting ATPase IB; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the [...]
Mtss1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079239Protein MTSS 1; Inhibits the nucleation of actin filaments in vitro.
Magel2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079265MAGE-like protein 2; Probably enhances ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases, possibly through recruitment and/or stabilization of the Ubl-con [...]
Oog2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079267Oogenesin-2.
Zfp251 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079268Zinc finger protein 251.
Zfp735 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079269Zinc finger protein 735.
Opn1sw protein networkhttps://string-db.org/network/10090.ENSMUSP00000079289Short-wave-sensitive opsin 1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal (By similarity). Requir [...]
Dennd5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000079295DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound R [...]
Tbpl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079309TATA box-binding protein-like protein 2; Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at [...]
Rpl36 protein networkhttps://string-db.org/network/10090.ENSMUSP0000007934060S ribosomal protein L36; Component of the large ribosomal subunit.
H1f5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079356Histone H1.5; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucle [...]
Rpp25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079358Ribonuclease P protein subunit p25; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclea [...]
2610301B20Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000079361Protein C8orf37 homolog; May be involved in photoreceptor outer segment disk morphogenesis.
Sbsn protein networkhttps://string-db.org/network/10090.ENSMUSP00000079362Suprabasin.
Defa24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079376Alpha-defensin 24; May have microbicidal activities; Belongs to the alpha-defensin family.
Abce1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079379ATP-binding cassette sub-family E member 1; Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'- linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhi [...]
Deaf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079395Deformed epidermal autoregulatory factor 1 homolog; Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. D [...]
Prl7b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079431Prolactin-7B1.
Mup19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079442Major urinary protein 6; Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females.
Tas2r114 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079453Taste receptor type 2 member 114; Putative taste receptor which may play a role in the perception of bitterness.
Fbxw22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079460F-box and WD-40 domain protein 22.
Scgb1b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079468Lacrimal androgen-binding protein eta.
Dnah9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079494Dynein, axonemal, heavy chain 9.
Gm4559 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079498ENSMUSG00000056885 protein.
Olfr1028 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079522Olfactory receptor.
Utp14a protein networkhttps://string-db.org/network/10090.ENSMUSP00000079538U3 small nucleolar RNA-associated protein 14 homolog A; May be required for ribosome biogenesis; Belongs to the UTP14 family.
Lypd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079543Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in tumor progression (By similarity).
Chsy3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079546Chondroitin sulfate synthase 3; Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosam [...]
Tax1bp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079548Tax1-binding protein 1 homolog; Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti- apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also p [...]
Sgip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079553SH3-containing GRB2-like protein 3-interacting protein 1; May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essent [...]
Sval3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079566Seminal vesicle autoantigen like protein 3.
Prl3d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079579Prolactin family 3, subfamily d, member 1.
Tpbpb protein networkhttps://string-db.org/network/10090.ENSMUSP00000079588Trophoblast-specific protein beta.
Zbtb24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079592Zinc finger and BTB domain-containing protein 24; May be involved in BMP2-induced transcription.
Cdh3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079613Cadherin-3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the s [...]
Olfr1475 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079616Olfactory receptor.
Zc3hc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079627Nuclear-interacting partner of ALK; Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of [...]
Rps17 protein networkhttps://string-db.org/network/10090.ENSMUSP0000007962840S ribosomal protein S17; Belongs to the eukaryotic ribosomal protein eS17 family.
Rnf169 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079631E3 ubiquitin-protein ligase RNF169; Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair site [...]
Zfp82 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079647Zinc finger protein 82; May be involved in transcriptional regulation.
Xlr3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000079651X-linked lymphocyte-regulated protein 3C.
Gm8882 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079660Predicted gene 8882.
Ipo11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079667Importin-11; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the [...]
H3c8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079670Histone H3.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones there [...]
Ccdc28a protein networkhttps://string-db.org/network/10090.ENSMUSP00000079671Coiled-coil domain-containing 28A.
Rpl35 protein networkhttps://string-db.org/network/10090.ENSMUSP0000007967260S ribosomal protein L35; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL29 family.
Dab2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079689Disabled homolog 2; Adapter protein that functions as clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Can bind and assemble clat [...]
Atp1a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079691Sodium/potassium-transporting ATPase subunit alpha-3; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium [...]
Pfkfb1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000796926-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; Synthesis and degradation of fructose 2,6-bisphosphate.
Dbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000079693D site-binding protein; This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential [...]
Krt17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079699Keratin, type I cytoskeletal 17; Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the c [...]
Amd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079703S-adenosylmethionine decarboxylase 2 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaini [...]
Thrap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079722Thyroid hormone receptor-associated protein 3; Involved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction compl [...]
Olfr704 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079726Olfactory receptor Olfr704.
Eno1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079727Enolase 1, alpha non-neuron.
Nxf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079730Nuclear RNA export factor 3.
Fes protein networkhttps://string-db.org/network/10090.ENSMUSP00000079733Tyrosine-protein kinase Fes/Fps; Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell at [...]
Lrp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079752Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor. Acts together with CUBN to mediate endocytosis of high-density lipoproteins. Mediates receptor-mediated uptake [...]
Tmem26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079789Transmembrane protein 26.
Krtap4-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079799Keratin associated protein 4-1.
Defb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079808Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) [...]
Zfp28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079812Zinc finger protein 28; May be involved in transcriptional regulation. May have a role in embryonic development.
Etv6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079818Transcription factor ETV6; Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation.
Zfp105 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079840Zinc finger protein 105.
Cenpi protein networkhttps://string-db.org/network/10090.ENSMUSP00000079851Centromere protein I; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chr [...]
Entpd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079864Ectonucleoside triphosphate diphosphohydrolase 7; Preferentially hydrolyzes nucleoside 5'-triphosphates. The order of activity with respect to possible substrates is UTP > GTP > CTP (By similarit [...]
Olfr913 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079876Olfactory receptor.
Timm17a protein networkhttps://string-db.org/network/10090.ENSMUSP00000079883Mitochondrial import inner membrane translocase subunit Tim17-A; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across [...]
Impdh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079888Inosine-5'-monophosphate dehydrogenase 2; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthe [...]
Slc24a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079897Sodium/potassium/calcium exchanger 3; Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
Myt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079900Myelin transcription factor 1; Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia [...]
Gm648 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079908Gene model 648, (NCBI).
Sycp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079909Synaptonemal complex protein 2; Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes. Requ [...]
Homez protein networkhttps://string-db.org/network/10090.ENSMUSP00000079929Homeobox and leucine zipper protein Homez; May function as a transcriptional regulator.
Sgcb protein networkhttps://string-db.org/network/10090.ENSMUSP00000079937Beta-sarcoglycan; Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Manbal protein networkhttps://string-db.org/network/10090.ENSMUSP00000079965Protein MANBAL.
Wdr91 protein networkhttps://string-db.org/network/10090.ENSMUSP00000079974WD repeat-containing protein 91; Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying [...]
Plcg2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000799911-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by acti [...]
Spink12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080025Serine protease inhibitor Kazal-type 12; Inhibits trypsin.
Serpinb12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080030Serpin B12; Inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator; Belongs to the serpin family. Ov-serpin subfamily.
Sfi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080066Protein SFI1 homolog; Plays a role in the dynamic structure of centrosome- associated contractile fibers via its interaction with CETN2.
Poteg protein networkhttps://string-db.org/network/10090.ENSMUSP00000080069POTE ankyrin domain family, member G.
Fxn protein networkhttps://string-db.org/network/10090.ENSMUSP00000080081Frataxin intermediate form; Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the p [...]
Rrp1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000080085Ribosomal RNA processing protein 1 homolog B; Positively regulates DNA damage-induced apoptosis by acting as a transcriptional coactivator of proapoptotic target genes of the transcriptional acti [...]
Hist1h2ap protein networkhttps://string-db.org/network/10090.ENSMUSP00000080088Histone cluster 1, H2ap.
Plac8l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080111PLAC8-like protein 1; Belongs to the cornifelin family.
Tcl1b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080115Protein TCL1B2; Belongs to the TCL1 family.
Nphp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080128Nephrocystin-4; Involved in the organization of apical junctions; the function is proposed to implicate a NPHP1-4-8 module. Does not seem to be strictly required for ciliogenesis (By similarity). [...]
Klk1b9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080133Kallikrein 1-related peptidase b9; Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin; Belongs to the peptidase S1 family. Kallikrein subfamily.
H2-Q4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080159Histocompatibility 2, Q region locus 4; Belongs to the MHC class I family.
Adrb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080162Beta-3 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta- 3 is involved in the regulation of [...]
Scnn1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000080164Amiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and [...]
Lgals7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080179Galectin-7; Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and [...]
Oas2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000802092'-5'-oligoadenylate synthase 2; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. Activated by detection of double stranded [...]
Ltbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080214Latent-transforming growth factor beta-binding protein 3; Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent [...]
Pop5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080215Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease co [...]
Pbx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080219Pre-B-cell leukemia transcription factor 4; Belongs to the TALE/PBX homeobox family.
Scoc protein networkhttps://string-db.org/network/10090.ENSMUSP00000080221Short coiled-coil protein; Positive regulator of amino acid starvation-induced autophagy; Belongs to the SCOC family.
Mgmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000080224Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the [...]
Alyref2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080242Aly/REF export factor 2; Export adapter involved in spliced and unspliced mRNA nuclear export. Binds mRNA which is transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway); enhances [...]
Acnat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080256Acyl-coenzyme A amino acid N-acyltransferase 2; Acyltransferase which efficiently conjugates very long-chain and long-chain fatty acids to taurine. Shows no conjugation activity in the presence o [...]
Kcnd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080257Potassium voltage-gated channel subfamily D member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in r [...]
Mtf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080278Metal-response element-binding transcription factor 2; Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Acts by binding [...]
Syt17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080284Synaptotagmin-17; Plays a role in dendrite formation by melanocytes. Belongs to the synaptotagmin family.
Zc3h15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080301Zinc finger CCCH domain-containing protein 15; Protects DRG1 from proteolytic degradation. Stimulates DRG1 GTPase activity likely by increasing the affinity for the potassium ions (By similarity) [...]
Pgk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080302Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition t [...]
Sh3pxd2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000080325SH3 and PX domain-containing protein 2A; Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metal [...]
Mettl15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080337Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase.
St7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080341Suppressor of tumorigenicity 7 protein; Belongs to the ST7 family.
Pramef6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080350PRAME family member 6.
Rpl3 protein networkhttps://string-db.org/network/10090.ENSMUSP0000008035460S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
Lypd11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080361Ly6/PLAUR domain-containing 11.
Gper1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080370G-protein coupled estrogen receptor 1; G-protein coupled estrogen receptor that binds to 17-beta- estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracel [...]
Ifnl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080384Interferon lambda-2; Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a l [...]
Srgap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080389SLIT-ROBO Rho GTPase-activating protein 1; GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of [...]
Olfr1193 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080399Olfactory receptor.
Trabd protein networkhttps://string-db.org/network/10090.ENSMUSP00000080403TraB domain-containing protein.
Hoga1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000804144-hydroxy-2-oxoglutarate aldolase, mitochondrial; Catalyzes the final step in the metabolic pathway of hydroxyproline.
Ezh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080419Histone-lysine N-methyltransferase EZH2; Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to t [...]
Eya3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080425Eyes absent homolog 3; Tyrosine phosphatase that specifically dephosphorylates 'Tyr- 142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repai [...]
Ctnnd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080427Catenin delta-2; Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses. Involved in the regulation of canonical Wnt signal [...]
Zfp985 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080438Zinc finger protein 985.
Olfr331 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080440Olfactory receptor 331.
Fam214a protein networkhttps://string-db.org/network/10090.ENSMUSP00000080442Protein FAM214A.
0610040J01Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000080443Uncharacterized protein C4orf19 homolog.
Olfr64 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080444Olfactory receptor.
Edil3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080462EGF-like repeat and discoidin I-like domain-containing protein 3; Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascu [...]
Nfe2l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080467Endoplasmic reticulum membrane sensor NFE2L1; [Endoplasmic reticulum membrane sensor NFE2L1]: Endoplasmic reticulum membrane sensor that translocates into the nucleus in response to various stres [...]
Apol9a protein networkhttps://string-db.org/network/10090.ENSMUSP00000080468Apolipoprotein L 9a.
Mug2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080469Murinoglobulin-2; A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester [...]
Tdpoz3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080472TD and POZ domain-containing protein 3.
Cacul1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080480CDK2-associated and cullin domain-containing protein 1; Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition.
Bpifb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080501BPI fold-containing family B member 1; May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS. May be in [...]
Bbof1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080512Basal body-orientation factor 1; Basal body protein required in multiciliate cells to align and maintain cilia orientation in response to flow. May act by mediating a maturation step that stabili [...]
Zdhhc12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080521Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family.
Tmeff2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080533Tomoregulin-2; May be a survival factor for hippocampal and mesencephalic neurons. The shedded form may up-regulate cell proliferation (By similarity).
Myh6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080538Myosin-6; Muscle contraction.
Tor4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000080548Torsin-4A.
Nell1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080550Protein kinase C-binding protein NELL1; Plays a role in the control of cell growth and differentiation. Promotes osteoblast cell differentiation and terminal mineralization.
Lamp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080556Lysosome-associated membrane glycoprotein 3; May play a role in dendritic cell function and in adaptive immunity.
Syn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080568Synapsin-1; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. Regulation of neurotransmit [...]
4930512M02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000080571RIKEN cDNA 4930512M02 gene.
Dysf protein networkhttps://string-db.org/network/10090.ENSMUSP00000080579Dysferlin; Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocy [...]
Ceacam5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080582Carcinoembryonic antigen-related cell adhesion molecule 5; Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and het [...]
Zfp341 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080596Zinc finger protein 341.
Serpinb9g protein networkhttps://string-db.org/network/10090.ENSMUSP00000080597Serine (Or cysteine) peptidase inhibitor, clade B, member 9g; Belongs to the serpin family.
Nmt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080600Glycylpeptide N-tetradecanoyltransferase 2; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.
Dtx3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000080601E3 ubiquitin-protein ligase DTX3L; E3 ubiquitin-protein ligase which, in association with ADP- ribosyltransferase PARP9, plays a role in DNA damage repair and in interferon-mediated antiviral res [...]
Krt87 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080613Keratin, type II cuticular 87; Belongs to the intermediate filament family.
Timm50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080614Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across th [...]
Olfr1328 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080626Olfactory receptor 1328.
Hopx protein networkhttps://string-db.org/network/10090.ENSMUSP00000080630Homeodomain-only protein; Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating th [...]
Odf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080632Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of [...]
Med9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080641Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Me [...]
Dzank1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080643Double zinc ribbon and ankyrin repeat-containing protein 1.
Olfr885 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080646Olfactory receptor Olfr885.
Rnf217 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080650Probable E3 ubiquitin-protein ligase RNF217; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the u [...]
Tas2r110 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080674Taste receptor type 2 member 110; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calc [...]
Mpp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080683MAGUK p55 subfamily member 5; Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells (By similarity). Also involved in adherens junction biogenesi [...]
Rps6ka6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080694Ribosomal protein S6 kinase alpha-6; Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent c [...]
Mageb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080706Melanoma antigen, family B, 5.
Erbb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080716Receptor tyrosine-protein kinase erbB-3; Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand [...]
Chil1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080717Chitinase-3-like protein 1; Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to an [...]
Tas2r131 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080736Taste receptor type 2.
Mamld1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080737Mastermind-like domain-containing protein 1; Transactivates the HES3 promoter independently of NOTCH proteins. HES3 is a non-canonical NOTCH target gene which lacks binding sites for RBPJ (By sim [...]
Ap3b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080739AP-3 complex subunit beta-2; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and [...]
Gzmd protein networkhttps://string-db.org/network/10090.ENSMUSP00000080742Granzyme D; This enzyme is probably necessary for target cell lysis in cell-mediated immune responses; Belongs to the peptidase S1 family. Granzyme subfamily.
Ptcd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080743Pentatricopeptide repeat domain-containing protein 3, mitochondrial; Mitochondrial RNA-binding protein that has a role in mitochondrial translation.
Csmd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080751CUB and sushi domain-containing protein 1; Belongs to the CSMD family.
Dut protein networkhttps://string-db.org/network/10090.ENSMUSP00000080767Deoxyuridine triphosphatase.
Ube2o protein networkhttps://string-db.org/network/10090.ENSMUSP00000080791(E3-independent) E2 ubiquitin-conjugating enzyme UBE2O; E2/E3 hybrid ubiquitin-protein ligase that displays both E2 and E3 ligase activities and mediates monoubiquitination of target proteins. Ne [...]
Fat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080808Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development.
Trim68 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080813E3 ubiquitin-protein ligase TRIM68; Functions as a ubiquitin E3 ligase. Acts as a coactivator of androgen receptor (AR) depending on its ubiquitin ligase activity.
Zc3h12b protein networkhttps://string-db.org/network/10090.ENSMUSP00000080820Zinc finger CCCH-type-containing 12B.
Hdac10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080832Polyamine deacetylase HDAC10; Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine. Exhibits attenuated catalytic ac [...]
Scn8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000080842Sodium channel protein type 8 subunit alpha; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage diff [...]
Cyp2b9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080846Cytochrome P450 2B9; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a var [...]
Chil4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080851Chitinase-like protein 4; Has low chemotactic activity for eosinophils. May play a role in inflammation and allergy. Has no chitinase activity. Belongs to the glycosyl hydrolase 18 family. Chitin [...]
Rpl5 protein networkhttps://string-db.org/network/10090.ENSMUSP0000008085460S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNA [...]
Mep1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000080866Meprin A subunit beta; Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1' position. Known substrates include: FGF19, [...]
Jakmip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080881Janus kinase and microtubule-interacting protein 2.
Mup5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080908Major urinary protein 5; Major urinary proteins (Mups) bind pheromones, and thus stabilize them to allow slow release into the air from urine marks. May protect pheromones from oxidation. May als [...]
Slc39a12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080911Zinc transporter ZIP12; Acts as a zinc-influx transporter.
Cr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080938Complement receptor type 2; Receptor for complement C3d and for HNRNPU. Participates in B lymphocytes activation; Belongs to the receptors of complement activation (RCA) family.
Mdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080949Mediator of DNA damage checkpoint protein 1; Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a [...]
Sult4a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080973Sulfotransferase 4A1; Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxin [...]
Luzp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080979Leucine zipper protein 2.
mt-Nd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080991NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for [...]
mt-Nd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080992NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for [...]
mt-Co1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080993Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain [...]
mt-Co2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080994Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain [...]
mt-Atp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080995ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated [...]
mt-Atp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080996ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated [...]
mt-Co3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080997Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain [...]
mt-Nd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000080998NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for [...]
mt-Nd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081000NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for [...]
mt-Nd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081001NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for [...]
mt-Nd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081002NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for [...]
mt-Cytb protein networkhttps://string-db.org/network/10090.ENSMUSP00000081003Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates ele [...]
Dio1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081007Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).
Sephs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081009Selenide, water dikinase 2; Synthesizes selenophosphate from selenide and ATP; Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Gpx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081010Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown.
Gpx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081011Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
Gpx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081012Glutathione peroxidase 2.
Dio2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081013Type II iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate leve [...]
Selenoo protein networkhttps://string-db.org/network/10090.ENSMUSP00000081020Protein adenylyltransferase SelO, mitochondrial; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr and Tyr residues of target proteins (AMPylation). May be a redox-active mit [...]
mt-Nd4l protein networkhttps://string-db.org/network/10090.ENSMUSP00000081021NADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required fo [...]
Fgfr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081041Fibroblast growth factor receptor 1; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic developmen [...]
Tacc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081043Transforming acidic coiled-coil-containing protein 1; Involved in transcription regulation induced by nuclear receptors, including in T3 thyroid hormone and all-trans retinoic acid pathways. Migh [...]
Htra4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081044Serine protease HTRA4; Serine protease; Belongs to the peptidase S1C family.
Defa37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081053Defensin, alpha, 36.
Defa32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081054Alpha-defensin 20; May have microbicidal activities; Belongs to the alpha-defensin family.
Defa20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081055Defensin, alpha, 20.
Gm15319 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081059Predicted gene 15319.
Cd209b protein networkhttps://string-db.org/network/10090.ENSMUSP00000081104CD209 antigen-like protein B; Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calciu [...]
Aurkaip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081114Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down- regulation through proteasome-dependent degradation; Belongs to the mitochondrion-specific riboso [...]
Plch1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000811221-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calciu [...]
Nol9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081133Polynucleotide 5'-hydroxyl-kinase NOL9; Polynucleotide 5'-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more [...]
Pgd protein networkhttps://string-db.org/network/10090.ENSMUSP000000811416-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
Tardbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000081142TAR DNA-binding protein 43; RNA-binding protein that is involved in various steps of RNA biogenesis and processing. Preferentially binds, via its two RNA recognition motifs RRM1 and RRM2, to GU-r [...]
Zfp820 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081158Zinc finger protein 820.
Zfp991 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081167Predicted gene, OTTMUSG00000010657.
Plekhm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081221Pleckstrin homology domain-containing family M member 2; May play a role in the regulation of conventional kinesin activity. Required for maintenance of the Golgi apparatus organization. May play [...]
Arhgef10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081225Rho guanine nucleotide exchange factor 10; May play a role in developmental myelination of peripheral nerves.
Eif4g3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081232Eukaryotic translation initiation factor 4 gamma 3; Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal s [...]
Zdhhc18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081260Palmitoyltransferase ZDHHC18; Has palmitoyltransferase activity towards HRAS and LCK.
Wasf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081263Wiskott-Aldrich syndrome protein family member 2; Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. [...]
Spocd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081284SPOC domain-containing 1.
Txlna protein networkhttps://string-db.org/network/10090.ENSMUSP00000081285Alpha-taxilin; May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.
Ago4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081312Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks [...]
Cdca8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081319Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct ch [...]
Akirin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081322Akirin-2; Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity). Required for embryonic development and the innate immune response. Downstream effector of the Tol [...]
Cldn19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081334Claudin-19; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Cyp4a32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081369Cytochrome P450, family 4, subfamily a, polypeptide 32; Belongs to the cytochrome P450 family.
Cyp4a12a protein networkhttps://string-db.org/network/10090.ENSMUSP00000081370Cytochrome P450 4A12A; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids and their oxygenated derivatives (oxylipins). Mechanistically, uses molecular oxygen inserting one [...]
Kif19a protein networkhttps://string-db.org/network/10090.ENSMUSP00000081398Kinesin-like protein KIF19; Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips; Belongs [...]
Mob2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081455MOB kinase activator 2; Stimulates the autophosphorylation and kinase activity of STK38 and STK38L.
Rplp2 protein networkhttps://string-db.org/network/10090.ENSMUSP0000008147460S acidic ribosomal protein P2; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family.
Olfr53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081494Olfactory receptor.
Cd163l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081497Scavenger receptor cysteine-rich type 1 protein CD163c-alpha.
Frmd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081514FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer.
Gm428 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081515Predicted gene 428.
Gm11238 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081519Predicted gene 11238.
Gm11487 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081520Predicted gene 11487.
Dock1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081531Dedicator of cytokinesis protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epith [...]
Abraxas2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081541BRISC complex subunit Abraxas 2; Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked polyubiquitin, leaving the last ubiquitin chain attached to its s [...]
Oat protein networkhttps://string-db.org/network/10090.ENSMUSP00000081544Ornithine aminotransferase, mitochondrial.
Pappa protein networkhttps://string-db.org/network/10090.ENSMUSP00000081545Pappalysin-1; Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cle [...]
Bub3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081547Mitotic checkpoint protein BUB3; Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes th [...]
Whrn protein networkhttps://string-db.org/network/10090.ENSMUSP00000081557Whirlin; Involved in hearing and vision as member of the USH2 complex. Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear. In [...]
Tacc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081561Transforming acidic coiled-coil-containing protein 2; Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-medi [...]
Wdr11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081567WD repeat-containing protein 11; Involved in the Hedgehog (Hh) signaling pathway, is essential for normal ciliogenesis. Regulates the proteolytic processing of GLI3 and cooperates with the transc [...]
Rgs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081569Regulator of G-protein signaling 3; Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-b [...]
Prpf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081572U4/U6 small nuclear ribonucleoprotein Prp4; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precat [...]
Cdc26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081573Anaphase-promoting complex subunit CDC26; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and t [...]
Slc31a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081574High affinity copper uptake protein 1; High-affinity, saturable copper transporter involved in dietary copper uptake.
Fkbp15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081575FK506-binding protein 15; Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement (By similarity). May be involved in th [...]
Slc31a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081578Probable low affinity copper uptake protein 2; Involved in low-affinity copper uptake; Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
Mup1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081596Major urinary protein 1; Belongs to the calycin superfamily. Lipocalin family.
Cln3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081636Battenin; Involved in microtubule-dependent, anterograde transport of late endosomes and lysosomes.
Cacng3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081664Voltage-dependent calcium channel gamma-3 subunit; Regulates the trafficking to the somatodendritic compartment and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes thei [...]
Anks6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081665Ankyrin repeat and SAM domain-containing protein 6; Required for renal function.
Tbc1d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081670TBC1 domain family member 2A; Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of ca [...]
Hs3st2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081678Heparan sulfate glucosamine 3-O-sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamin [...]
Abca14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081690ATP-binding cassette, sub-family A (ABC1), member 14.
Spag8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081696Sperm-associated antigen 8; Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5- regulated transcriptional activation of C [...]
Gpr139 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081700Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway.
Dnajb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081712DnaJ homolog subfamily B member 5.
Galt protein networkhttps://string-db.org/network/10090.ENSMUSP00000081745Galactose-1-phosphate uridylyltransferase; Plays an important role in galactose metabolism.
Fyco1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081764FYVE and coiled-coil domain-containing protein 1; May mediate microtubule plus end-directed vesicle transport.
Ak6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081772Transcription initiation factor TFIID subunit 9; Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of [...]
Ipo7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081782Importin-7; Functions in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Actin [...]
Tmem42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081784Transmembrane protein 42.
Olfr514 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081807Olfactory receptor.
Nlrp14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081819NACHT, LRR and PYD domains-containing protein 14; May be involved in inflammation and spermatogenesis. Belongs to the NLRP family.
Fut9 protein networkhttps://string-db.org/network/10090.ENSMUSP000000818264-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9; Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal [...]
Scn10a protein networkhttps://string-db.org/network/10090.ENSMUSP00000081845Sodium channel protein type 10 subunit alpha; Tetrodotoxin-resistant channel that mediates the voltage- dependent sodium ion permeability of excitable membranes. Assuming opened or closed conform [...]
Slc22a13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081855Solute carrier family 22 member 13.
Dnah17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081864Dynein heavy chain 17, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke [...]
Dnah11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081867Dynein, axonemal, heavy chain 11.
Olfr586 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081872Olfactory receptor.
Olfr575 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081873Olfactory receptor.
Golga4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081880Golgin subfamily A member 4; Involved in vesicular trafficking at the Golgi apparatus level. May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi [...]
Ncapg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081889Condensin-2 complex subunit G2; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid ax [...]
Chrna10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081891Cholinergic receptor, nicotinic, alpha polypeptide 10.
Xntrpc protein networkhttps://string-db.org/network/10090.ENSMUSP00000081903Short transient receptor potential channel 2; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger s [...]
Numa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081912Nuclear mitotic apparatus protein 1; Microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignement and the segregation of chromosomes [...]
Crtap protein networkhttps://string-db.org/network/10090.ENSMUSP00000081941Cartilage-associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues; Belongs to the leprecan family.
Crip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081943Cysteine-rich protein 2.
Ubp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081946Upstream-binding protein 1; Functions as a transcriptional activator in a promoter context-dependent manner. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the [...]
Gxylt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081947Glucoside xylosyltransferase 1; Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of x [...]
Pacs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081953Phosphofurin acidic cluster sorting protein 2; Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria wi [...]
Dpy19l4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081954Probable C-mannosyltransferase DPY19L4; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.
Gm45837 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081956Phosphodiesterase.
Pgm2l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000081998Glucose 1,6-bisphosphate synthase; Glucose 1,6-bisphosphate synthase using 1,3- bisphosphoglycerate as a phosphate donor and a series of 1-phosphate sugars as acceptors, including glucose 1-phosp [...]
Klc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082004Kinesin light chain 1; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chai [...]
Trmt61a protein networkhttps://string-db.org/network/10090.ENSMUSP00000082011tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 5 [...]
Impad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082013Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase; Exhibits 3'-nucleotidase activity toward adenosine 3',5'- bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adeno [...]
Mark3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082017MAP/microtubule affinity-regulating kinase 3; Serine/threonine-protein kinase. Involved in the specific phosphorylation of microtubule-associated proteins for MAPT/TAU, MAP2 and MAP4. Phosphoryla [...]
Fbxw16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082051F-box and WD-40 domain protein 16.
Ppp2r5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000082053Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the lo [...]
Rpl10 protein networkhttps://string-db.org/network/10090.ENSMUSP0000008205560S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development.
Ip6k2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082091Inositol hexakisphosphate kinase 2; Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5) (By similarity). May play a role in the regulation of Na(+)- [...]
Nhlrc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082102NHL-repeat-containing protein 4.
Gpr171 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082115Probable G-protein coupled receptor 171; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Tcl1b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082118Protein TCL1B1; Belongs to the TCL1 family.
Serpina3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000082125Serine protease inhibitor A3C.
Serpina3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000082127Serine protease inhibitor A3B.
Amigo3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082137Amphoterin-induced protein 3; May mediate heterophilic cell-cell interaction. May contribute to signal transduction through its intracellular domain (By similarity); Belongs to the immunoglobulin [...]
Ifi27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082142Interferon, alpha-inducible protein 27 like 1.
Actl11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082150Actin-like 11; Belongs to the actin family.
Arnt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082154Aryl hydrocarbon receptor nuclear translocator 2; Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal functio [...]
Mex3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000082168RNA-binding protein MEX3B; RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms (By similarity).
Cish protein networkhttps://string-db.org/network/10090.ENSMUSP00000082183Cytokine-inducible SH2-containing protein; SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regu [...]
Iqcf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082192Testis-specific IQ motif containing protein 1.
Iqcf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082194IQ domain-containing protein F5.
Iqcf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082195IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction.
Ptpn21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082197Tyrosine-protein phosphatase non-receptor type 21; May be involved in the regulation of growth and differentiation of liver cells; Belongs to the protein-tyrosine phosphatase family. Non- recepto [...]
Tlr9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082207Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific [...]
Atp2c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082220Calcium-transporting ATPase type 2C member 1; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium.
Gm13023 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082232Predicted gene 13023.
Msl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082270E3 ubiquitin-protein ligase MSL2; Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher [...]
Aldh6a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082288Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA (By similarity).
Slc25a36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082302Solute carrier family 25 member 36; Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Transports preferentially cytosine and uracil (deoxy)nucleosi [...]
Trpm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082318Transient receptor potential cation channel subfamily M member 1; Cation channel essential for the depolarizing photoresponse of retinal ON bipolar cells. It is part of the GRM6 signaling cascade [...]
Slc39a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082343Zinc transporter ZIP9; May act as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family.
Morf4l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082346Mortality factor 4-like protein 1; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosoma [...]
Mthfs protein networkhttps://string-db.org/network/10090.ENSMUSP000000823545-formyltetrahydrofolate cyclo-ligase; Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for th [...]
Daam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082406Disheveled-associated activator of morphogenesis 1; Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho- [...]
Adam4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082427A disintegrin and metallopeptidase domain 4.
Ccpg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082458Cell cycle progression protein 1; Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibitio [...]
Hrc protein networkhttps://string-db.org/network/10090.ENSMUSP00000082459Histidine-rich calcium-binding protein.
Slc17a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082489Vesicular glutamate transporter 1; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic p [...]
Pih1d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082490PIH1 domain-containing protein 1; Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (By similarity). Recruits the SWI/SNF complex to the core promoter of rR [...]
Brms1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000082500Breast cancer metastasis-suppressor 1-like protein; Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity. When overexpressed in lung cancer cell line that lac [...]
Scaf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082501Splicing factor, arginine/serine-rich 19; May function in pre-mRNA splicing; Belongs to the splicing factor SR family.
Ralgapa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082503Ral GTPase-activating protein subunit alpha-1; Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB (By similarity) [...]
Izumo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082543Izumo sperm-egg fusion protein 2.
Isg15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082548Ubiquitin-like protein ISG15; Ubiquitin-like protein which plays a key role in the innate immune response to viral infection either via its conjugation to a target protein (ISGylation) or via its [...]
Klk1b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082577Kallikrein 1-related peptidase b3; 7S NGF alpha chain stabilizes the 7S complex. The beta dimer promotes neurite growth. The gamma chain is an arginine-specific protease; it may also have plasmin [...]
Rasl12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082580Ras-like protein family member 12; Belongs to the small GTPase superfamily. Ras family.
Klk1b21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082582Kallikrein 1-related peptidase b21; Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Displays trypsin-like substrate specificity and shows activity t [...]
Klk8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082588Kallikrein-8; Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increas [...]
Uri1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082646Unconventional prefoldin RPB5 interactor; Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) tra [...]
Anp32a protein networkhttps://string-db.org/network/10090.ENSMUSP00000082652Acidic leucine-rich nuclear phosphoprotein 32 family member A; Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent a [...]
Hmgb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082682High mobility group protein B1; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone [...]
Grhl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082689Grainyhead-like protein 1 homolog; Transcription factor involved in epithelial development. Binds directly to the consensus DNA sequence 5'-AACCGGTT-3'. Important regulator of DSG1 in the context [...]
Utp25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082691Digestive organ expansion factor homolog; Regulates the p53 pathway to control the expansion growth of digestive organs; Belongs to the def family.
Mtus2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082694Microtubule-associated tumor suppressor candidate 2 homolog; Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate t [...]
Traf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082710TNF receptor-associated factor 5; Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the rec [...]
Lsm14a protein networkhttps://string-db.org/network/10090.ENSMUSP00000082723Protein LSM14 homolog A; Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs. Belongs to the LSM14 family.
Pdx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082729Pancreas/duodenum homeobox protein 1; Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the panc [...]
Usp12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082754Ubiquitin carboxyl-terminal hydrolase 12; Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved [...]
Scgb1b27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082758Secretoglobin, family 1B, member 27.
Scgb2b27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082760Secretoglobin, family 2B, member 27.
Scgb2b26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082763Salivary androgen-binding protein gamma subunit.
Flvcr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082777Feline leukemia virus subgroup C receptor-related protein 1; [Isoform 1]: Heme transporter that exports cytoplasmic heme. It can also export coproporphyrin and protoporphyrin IX, which are both i [...]
Nptn protein networkhttps://string-db.org/network/10090.ENSMUSP00000082793Neuroplastin.
Insyn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082800Inhibitory synaptic factor 1; Component of the protein machinery at the inhibitory synapses, probably acting as a scaffold. Inhibitory synapses dampen neuronal activity through postsynaptic hyper [...]
Zkscan5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082814Zinc finger protein with KRAB and SCAN domains 5; May be involved in transcriptional regulation.
Pml protein networkhttps://string-db.org/network/10090.ENSMUSP00000082816Protein PML; Functions via its association with PML-nuclear bodies (PML- NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, [...]
Kctd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082821BTB/POZ domain-containing protein KCTD3; Accessory subunit of potassium/sodium hyperpolarization- activated cyclic nucleotide-gated channel 3 (HCN3) upregulating its cell-surface expression and c [...]
Arpc1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000082822Actin-related protein 2/3 complex subunit 1B; Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The [...]
Smurf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082827E3 ubiquitin-protein ligase SMURF1; E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway (By similarity). Mediates ubiquitination and degradation of SMAD1 and SM [...]
Tecpr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082844Tectonin beta-propeller repeat-containing protein 1; Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by ass [...]
Stat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082855Signal transducer and activator of transcription 2; Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding [...]
Ppcdc protein networkhttps://string-db.org/network/10090.ENSMUSP00000082856Phosphopantothenoylcysteine decarboxylase; Necessary for the biosynthesis of coenzyme A. Catalyzes the decarboxylation of 4-phosphopantothenoylcysteine to form 4'- phosphopantotheine (By similari [...]
Mark4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082862MAP/microtubule affinity-regulating kinase 4; Serine/threonine-protein kinase (By similarity). Phosphorylates the microtubule-associated protein MAPT/TAU (By similarity). Also phosphorylates the [...]
Susd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082873Sushi domain-containing protein 4; Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bou [...]
Spdye4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000082882Speedy protein E4A; Promotes progression through the cell cycle via binding and activation of CDK1; Belongs to the Speedy/Ringo family.
Ttc32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082891Tetratricopeptide repeat protein 32.
Wdr35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082895WD repeat-containing protein 35; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it i [...]
Radil protein networkhttps://string-db.org/network/10090.ENSMUSP00000082910Ras-associating and dilute domain-containing protein; Downstream effector of Rap required for cell adhesion and migration of neural crest precursors during development.
Sdk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082928Protein sidekick-1; Adhesion molecule that promotes lamina-specific synaptic connections in the retina. Expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promote [...]
Card11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082941Caspase recruitment domain-containing protein 11; Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell prolifera [...]
Zfp940 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082947Zinc finger protein 940.
Lefty2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082952Left-right determination factor 2; Required for left-right asymmetry determination of organ systems in mammals; Belongs to the TGF-beta family.
Sipa1l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082965Signal-induced proliferation-associated 1-like protein 3; Plays a critical role in epithelial cell morphogenesis, polarity, adhesion and cytoskeletal organization in the lens.
Ncoa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082971Nuclear receptor coactivator 1; Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone- dependent fashion. Involved in the c [...]
Kcnk6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082975Potassium channel subfamily K member.
Map4k1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000082995Mitogen-activated protein kinase kinase kinase kinase 1; Serine/threonine-protein kinase, which may play a role in the response to environmental stress (By similarity). Appears to act upstream of [...]
Zfp157 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083018Zinc finger protein 157.
Ifi208 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083039Pyrin domain-containing protein 3; Belongs to the HIN-200 family.
Smok3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000083049Sperm motility kinase 3A; May play a role in sperm motility, especially in the regulation of flagellar function; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Smo [...]
Cfap45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083057Cilia and flagella-associated protein 45.
Atp1a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083077Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium [...]
Fxyd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083101FXYD domain-containing ion transport regulator 6; Belongs to the FXYD family.
Nlrp9c protein networkhttps://string-db.org/network/10090.ENSMUSP00000083106NACHT, LRR and PYD domains-containing protein 9C; May be involved in inflammation; Belongs to the NLRP family.
Bud23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083146Probable 18S rRNA (guanine-N(7))-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA. Requires the methy [...]
Galnt17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083187Polypeptide N-acetylgalactosaminyltransferase 17; May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or th [...]
Caln1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083193Calcium-binding protein 8; Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of ne [...]
F5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083204Coagulation factor V heavy chain; Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to t [...]
Clasrp protein networkhttps://string-db.org/network/10090.ENSMUSP00000083205CLK4-associating serine/arginine rich protein; Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the [...]
Olfr983 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083206Olfactory receptor MOR162-1.
Nipsnap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083211Protein NipSnap homolog 2; May act as a positive regulator of L-type calcium channels.
Gm6502 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083215Predicted gene 6502.
Piwil1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083222Piwi-like protein 1; Endoribonuclease that plays a central role in postnatal germ cells by repressing transposable elements and preventing their mobilization, which is essential for the germline [...]
Olfr878 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083228Olfactory receptor.
Olfr145 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083229Olfactory receptor 145; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Scarb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083242Scavenger receptor class B member 1; Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (By similarity). Both isoform 1 [...]
Ncor2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083250Nuclear receptor corepressor 2; Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access [...]
Tnfsf18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083251Tumor necrosis factor ligand superfamily member 18; Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activati [...]
Prkd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083273Serine/threonine-protein kinase D2; Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in [...]
Ap2s1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083281AP-2 complex subunit sigma; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via Transport vesicles in different membrane traffic pathway [...]
Sec16b protein networkhttps://string-db.org/network/10090.ENSMUSP00000083300Protein transport protein Sec16B; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory c [...]
Sult2a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083317Sulfotransferase; Belongs to the sulfotransferase 1 family.
Sprr2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083330Small proline-rich protein 2A3; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membran [...]
Nfrkb protein networkhttps://string-db.org/network/10090.ENSMUSP00000083341Nuclear factor related to kappa-B-binding protein; Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.
Zfp648 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083370Zinc finger protein 648.
Glul protein networkhttps://string-db.org/network/10090.ENSMUSP00000083375Glutamine synthetase; Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity). Its role depends on tissue localization: in the brain [...]
Rnasel protein networkhttps://string-db.org/network/10090.ENSMUSP000000833852-5A-dependent ribonuclease; Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects th [...]
Vmn2r54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083386Vomeronasal 2, receptor 54.
Anapc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083393Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G [...]
Vmn1r84 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083405Vomeronasal type-1 receptor.
Aurkc protein networkhttps://string-db.org/network/10090.ENSMUSP00000083426Aurora kinase C; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions a [...]
Zfp810 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083459Zinc finger protein 810.
Zfp599 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083462Zinc finger protein 599.
Vmn2r42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083463Putative pheromone receptor.
Vmn2r28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083477Vomeronasal 2, receptor 28.
Sh2b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083490SH2B adapter protein 3; Links T-cell receptor activation signal to phospholipase C- gamma-1, GRB2 and phosphatidylinositol 3-kinase; Belongs to the SH2B adapter family.
Vmn1r65 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083520Vomeronasal type-1 receptor.
Milr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083538Allergin-1; Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate [...]
AB124611 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083547Protein HIDE1.
Tmem150b protein networkhttps://string-db.org/network/10090.ENSMUSP00000083549Modulator of macroautophagy TMEM150B; Modulator of macroautophagy that causes accumulation of autophagosomes under basal conditions and enhances autophagic flux (By similarity). Represses cell de [...]
Oas1g protein networkhttps://string-db.org/network/10090.ENSMUSP000000835552'-5' oligoadenylate synthetase 1G.
1700007K13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000083557UPF0691 protein C9orf116 homolog.
Gpr25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083583Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Icam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083587Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement pro [...]
Lair1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083589Leukocyte-associated immunoglobulin-like receptor 1; Functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-c [...]
Nck2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083611Cytoplasmic protein NCK2; Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by pro [...]
Col5a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083620Collagen alpha-2(V) chain; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collag [...]
Rfc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083652Replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) [...]
Adora1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083656Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family.
Olfr18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083664Olfactory receptor 18; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr872 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083665Olfactory receptor.
Olfr834 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083680Olfactory receptor.
Rplp0 protein networkhttps://string-db.org/network/10090.ENSMUSP0000008370560S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
Cntn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083707Contactin-2; In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at t [...]
Pxn protein networkhttps://string-db.org/network/10090.ENSMUSP00000083709Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
Rpl31 protein networkhttps://string-db.org/network/10090.ENSMUSP0000008372260S ribosomal protein L31; Belongs to the eukaryotic ribosomal protein eL31 family.
Gm10188 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083731Predicted gene 10188.
Dhx57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083742Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase.
Elk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083743ETS domain-containing protein Elk-4; Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and stabilization of SIRT7 at promoters, followed by d [...]
Slc41a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083747Solute carrier family 41 member 1; Acts as a magnesium transporter that is responsive to magnesium balance; Belongs to the SLC41A transporter family.
Trmo protein networkhttps://string-db.org/network/10090.ENSMUSP00000083752tRNA (adenine(37)-N6)-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoylade [...]
Git2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083754ARF GTPase-activating protein GIT2; GTPase-activating protein for the ADP ribosylation factor family.
Tmem211 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083808Transmembrane protein 211.
Myo18b protein networkhttps://string-db.org/network/10090.ENSMUSP00000083810Myosin XVIIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Alk protein networkhttps://string-db.org/network/10090.ENSMUSP00000083840ALK tyrosine kinase receptor; Neuronal receptor tyrosine kinase that is essentially and transiently expressed in specific regions of the central and peripheral nervous systems and plays an import [...]
Pus1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083844tRNA pseudouridine synthase A; Converts specific uridines to PSI in a number of tRNA substrates. Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an [...]
Plcxd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083892PI-PLC X domain-containing protein 1.
Serpinb7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083896Serpin B7; Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin (By similarity); Belongs to the serpin family. Ov- [...]
Mtcl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083899Microtubule cross-linking factor 1; Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation. Plays a role in the development and ma [...]
Serpinb3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000083901Serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B; Belongs to the serpin family.
Man2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083928Alpha-mannosidase 2; Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N- glycans; the final hydrolytic step in the N- [...]
Cntnap5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000083944Contactin-associated protein like 5-2; May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercel [...]
Adgre1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000083971Adhesion G protein-coupled receptor E1; Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regu [...]
Barhl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084005BarH-like 2 homeobox protein; Potential regulator of neural basic helix-loop-helix genes. It may down-regulate expression of ASCL1 and, within the thalamus, up- regulate NGN2, thereby regulating [...]
Bicd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084039Protein bicaudal D homolog 1; Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex; Belongs to the Bi [...]
Pkd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084041Polycystin-2; Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Can [...]
Spp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084043Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction; Belongs to the osteopontin family.
Asb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084054Ankyrin repeat and SOCS box protein 1; May play a role in testis development. Probable substrate- recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ligase complex which [...]
Tcf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084055Transcription factor 7; Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal C [...]
Hes6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084062Transcription cofactor HES-6; Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-me [...]
Erfe protein networkhttps://string-db.org/network/10090.ENSMUSP00000084073Erythroferrone; Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression [...]
Yju2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084082Splicing factor YJU2; Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the [...]
Pot1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000084089Protection of telomeres 1B.
Asb18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084095Ankyrin repeat and SOCS box protein 18; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquit [...]
Armcx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084097Armadillo repeat-containing X-linked protein 3; Regulates mitochondrial aggregation and transport in axons in living neurons. May link mitochondria to the Trak2-kinesin motor complex via its inte [...]
Gm7971 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084169Predicted gene 16429.
Mfsd13a protein networkhttps://string-db.org/network/10090.ENSMUSP00000084189Transmembrane protein 180.
Gpr55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084196G-protein coupled receptor 55; Receptor for L-alpha-lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA (By simila [...]
Cdkl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084199Cyclin-dependent kinase-like 2; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Slc22a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084234Solute carrier family 22 member 7; Mediates sodium-independent multispecific organic anion transport. High affinity transport of glutarate and prostaglandin E2 in a sodium-independent manner. Med [...]
Polr1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000084252DNA-directed RNA polymerases I and III subunit RPAC1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common co [...]
Xpo5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084257Exportin-5; Mediates the nuclear export of proteins bearing a double- stranded RNA binding domain (dsRBD) and double-stranded RNAs (cargos). XPO5 in the nucleus binds cooperatively to the RNA and [...]
Jchain protein networkhttps://string-db.org/network/10090.ENSMUSP00000084259Immunoglobulin J chain; Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it in [...]
Col4a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084282Collagen alpha-4(IV) chain; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and [...]
Nhs protein networkhttps://string-db.org/network/10090.ENSMUSP00000084319NHS actin-remodeling regulator.
Mrgpra4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084327Mas-related G-protein coupled receptor member A4; Orphan receptor. May be a receptor for RFamide-family neuropeptides such as NPFF and NPAF, which are analgesic in vivo. May regulate nociceptor f [...]
Cdkl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084342Cyclin-dependent kinase-like 5; Mediates phosphorylation of MECP2. May regulate ciliogenesis.
Cenpq protein networkhttps://string-db.org/network/10090.ENSMUSP00000084353Centromere protein Q; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chr [...]
Speg protein networkhttps://string-db.org/network/10090.ENSMUSP00000084361Striated muscle-specific serine/threonine-protein kinase; Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells.
Eif1ax protein networkhttps://string-db.org/network/10090.ENSMUSP00000084387Eukaryotic translation initiation factor 1A, X-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding [...]
Klhl34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084399Kelch-like 34.
Trim40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084400Tripartite motif-containing protein 40; May function as an E3 ubiquitin-protein ligase of the NEDD8 conjugation pathway. Promotes neddylation of IKBKG/NEMO, stabilizing NFKBIA, and inhibiting of [...]
Lnx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084405E3 ubiquitin-protein ligase LNX; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquiti [...]
H2-M9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084411Histocompatibility 2, M region locus 9; Belongs to the MHC class I family.
Gemin8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084414Gem-associated protein 8; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important r [...]
Opalin protein networkhttps://string-db.org/network/10090.ENSMUSP00000084422Opalin; Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
Lrrc66 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084423Leucine-rich repeat-containing protein 66.
Dcun1d4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084427DCN1-like protein 4.
Stk36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084430Serine/threonine-protein kinase 36; Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Cont [...]
Ociad2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084445OCIA domain-containing protein 2.
Gnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084450Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster.
Fry protein networkhttps://string-db.org/network/10090.ENSMUSP00000084454Protein furry homolog; Plays a crucial role in the structural integrity of mitotic centrosomes and in the maintenance of spindle bipolarity by promoting PLK1 activity at the spindle poles in earl [...]
Ppp1r10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084461Serine/threonine-protein phosphatase 1 regulatory subunit 10; Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of [...]
Nipal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084462Magnesium transporter NIPA3; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+ [...]
Cnga1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084464cGMP-gated cation channel alpha-1; Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, c [...]
Cnot9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084466CCR4-NOT transcription complex subunit 9; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA de [...]
Nfxl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084467Nuclear transcription factor, X-box-binding-like 1.
Guf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084480Translation factor Guf1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRN [...]
Cyp2c66 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084487Cytochrome P450, family 2, subfamily c, polypeptide 66; Belongs to the cytochrome P450 family.
Cyp2c65 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084489Cytochrome P450, family 2, subfamily c, polypeptide 65; Belongs to the cytochrome P450 family.
Shisa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084494Protein shisa-3 homolog; Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. Belongs to the shisa family.
Abca12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084523ATP-binding cassette, sub-family A (ABC1), member 12.
Foxd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084541Forkhead box protein D3; Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural [...]
Vars protein networkhttps://string-db.org/network/10090.ENSMUSP00000084572Valine--tRNA ligase.
Capn6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084573Calpain-6; Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interactio [...]
Ddhd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084577Phospholipase DDHD1; Phospholipase that hydrolyzes phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid. The different isoforms may change the substrate specificity (By similarity). Req [...]
Ppp1r3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000084578Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limi [...]
Pgm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084582Phosphoglucomutase-2; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5- phosphopentoses. May also catalyze the i [...]
Hspa1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000084586Heat shock 70 kDa protein 1A; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized [...]
Gm16223 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084590Predicted gene 16223.
Kif20b protein networkhttps://string-db.org/network/10090.ENSMUSP00000084599Kinesin-like protein KIF20B; Plus-end-directed motor enzyme that is required for completion of cytokinesis (By similarity). Required for proper midbody organization and abscission in polarized co [...]
Cryge protein networkhttps://string-db.org/network/10090.ENSMUSP00000084617Gamma-crystallin E; Crystallins are the dominant structural components of the vertebrate eye lens.
Adam23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084633Disintegrin and metalloproteinase domain-containing protein 23; May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein (By similarity).
Kcnip4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084656Kv channel-interacting protein 4; Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels, such as KCND2/Kv4.2 and KCND3/Kv4.3. Modulates channel expr [...]
Morc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084663MORC family CW-type zinc finger protein 4.
Bmpr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084701Bone morphogenetic protein receptor type-2; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphor [...]
Tuba3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000084713Detyrosinated tubulin alpha-3 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site [...]
Col11a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084772Collagen alpha-2(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils; Belongs to the fibrillar collagen family.
Tmem128 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084788Transmembrane protein 128.
Lyar protein networkhttps://string-db.org/network/10090.ENSMUSP00000084791Cell growth-regulating nucleolar protein; Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and [...]
Dido1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084794Death-inducer obliterator 1; Required for early embryonic stem cell development (By similarity). Putative transcription factor, weakly pro-apoptotic when overexpressed.
Nif3l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084799NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
B3galt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084823Beta-1,3-galactosyltransferase 4; Involved in GM1/GD1B/GA1 ganglioside biosynthesis. Belongs to the glycosyltransferase 31 family.
Tspan6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084838Tetraspanin-6.
Aldoa protein networkhttps://string-db.org/network/10090.ENSMUSP00000084846Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity). Belongs to the class I fructose-bispho [...]
Trpm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084857Transient receptor potential cation channel, subfamily M, member 3.
Boll protein networkhttps://string-db.org/network/10090.ENSMUSP00000084868Protein boule-like; Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation (By similarity); Belongs [...]
Gda protein networkhttps://string-db.org/network/10090.ENSMUSP00000084882Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
Myo1f protein networkhttps://string-db.org/network/10090.ENSMUSP00000084887Unconventional myosin-If; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind [...]
Plekha5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084904Pleckstrin homology domain-containing, family A member 5.
Adamts10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084905A disintegrin and metalloproteinase with thrombospondin motifs 10; Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independen [...]
Htra3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084910Serine protease HTRA3; Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits si [...]
Zfp763 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084936Zinc finger protein 763.
Zfp952 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084949Zinc finger protein 952.
Hmx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084958Homeobox protein HMX1; DNA-binding protein that binds to the 5'-CAAG-3' core sequence. May function as a transcriptional repressor. Seems to act as a transcriptional antagonist of NKX2-5. May pla [...]
Dera protein networkhttps://string-db.org/network/10090.ENSMUSP00000084959Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. Participates in stress granu [...]
Prune2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000084977Protein prune homolog 2; May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells.
H4c11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085006Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby [...]
Ephx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085013Epoxide hydrolase 3; Catalyzes the hydrolysis of epoxide-containing fatty acids. Active in vitro against epoxyeicosatrienoic acids (EETs) including 8,9- EET, 9,10-EET, 11,12-EET and 14,15-EET and [...]
Notch3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085016Neurogenic locus notch homolog protein 3; Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the re [...]
Gsg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085022Germ cell-specific gene 1 protein; May cause the redistribution of PAPOLB from the cytosol to the endoplasmic reticulum; Belongs to the GSG1 family.
Tnip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085030TNFAIP3-interacting protein 2; Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appea [...]
Olfr1453 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085071Olfactory receptor.
Olfr1436 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085113Olfactory receptor.
Olfr262 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085120Olfactory receptor.
Prb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085159Proline-rich protein BstNI subfamily 1.
Uvssa protein networkhttps://string-db.org/network/10090.ENSMUSP00000085170UV-stimulated scaffold protein A; Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rap [...]
Uprt protein networkhttps://string-db.org/network/10090.ENSMUSP00000085175Uracil phosphoribosyltransferase homolog.
Nexmif protein networkhttps://string-db.org/network/10090.ENSMUSP00000085187Neurite extension and migration factor; Involved in neurite outgrowth by regulating cell-cell adhesion via the N-cadherin signaling pathway. May act by regulating expression of protein-coding gen [...]
Col3a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085192Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in [...]
Stx16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085218Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family.
Hdac8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085226Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic rep [...]
Ms4a15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085234Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family.
Tpp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085244Tripeptidyl-peptidase 2; Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to [...]
Rab44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085253Ras-related protein Rab-44.
Med12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085260Mediator of RNA polymerase II transcription subunit 12; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Cbln4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085263Cerebellin-4; Acts as a synaptic organizer in specific subsets of neurons in the brain. Essential for the formation and maintenance of inhibitory GABAergic synapses. Promotes the development of d [...]
Zfp64 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085285Zinc finger protein 64; May be involved in transcriptional regulation.
S1pr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085293Sphingosine 1-phosphate receptor 3; Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of [...]
Dlg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085299Disks large homolog 3; Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling.
Krt77 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085311Keratin, type II cytoskeletal 1b.
Adnp protein networkhttps://string-db.org/network/10090.ENSMUSP00000085316Activity-dependent neuroprotector homeobox protein; Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proli [...]
Gtf3c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085325General transcription factor 3C polypeptide 2; Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required fo [...]
Nms protein networkhttps://string-db.org/network/10090.ENSMUSP00000085346Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions; Belongs to the NmU family.
Klri1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085362Killer cell lectin-like receptor subfamily I member 1; Lectin-like receptor for natural killer (NK) cells. Heterodimer formation with KLRE1 mediates inhibition of NK cell cytolytic activity.
Krt86 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085365Keratin, type II cuticular Hb6; Belongs to the intermediate filament family.
Ncoa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085416Nuclear receptor coactivator 3; Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone- dependent fashion. Plays a central r [...]
Zfx protein networkhttps://string-db.org/network/10090.ENSMUSP00000085423Zinc finger X-chromosomal protein; Probable transcriptional activator; Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily.
Adgrf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085440Adhesion G-protein coupled receptor F3; Orphan receptor.
Mettl7a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085467Methyltransferase-like 7A2.
4930415L06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000085471Protein PPP4R3C; Belongs to the SMEK family.
Hs6st2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085497Heparan-sulfate 6-O-sulfotransferase 2; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine resi [...]
Hs6st1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085499Heparan-sulfate 6-O-sulfotransferase 1; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine resi [...]
Obp1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000085528Odorant-binding protein 1b; Binds the chemical odorant 2-isobutyl-3-methoxypyrazine.
Obp1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000085531Odorant-binding protein 1a; Binds the chemical odorant 2-isobutyl-3-methoxypyrazine.
Tbl1x protein networkhttps://string-db.org/network/10090.ENSMUSP00000085549F-box-like/WD repeat-containing protein TBL1X; F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an e [...]
Trpt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085555tRNA 2'-phosphotransferase 1; Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP- ribose 1''-2'' cyclic phosphate; [...]
Fmnl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085566Formin-like protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. Required for developmental angiogenesi [...]
Gm10220 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085569Predicted gene 10220.
Actr3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000085578Actin-related protein 3B; Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymeri [...]
Tuba3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000085580Tubulin, alpha 3A.
Ube2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000085581Ubiquitin-conjugating enzyme E2 C; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitinati [...]
Wfdc13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085594WAP four-disulfide core domain protein 13; Putative acid-stable proteinase inhibitor.
Rab23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085625Ras-related protein Rab-23; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle bet [...]
Acrbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000085632Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin.
Chpf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085633Hexosyltransferase.
Iqca1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000085642IQ and AAA domain-containing protein 1-like.
Gbx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085651Homeobox protein GBX-1.
Mapk8ip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085683C-Jun-amino-terminal kinase-interacting protein 3; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK c [...]
Atn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085695Atrophin-1; Transcriptional corepressor. Corepressor of MTG8 transcriptional repression. Has some intrinsic repression activity which is independent of the number of the poly-Q repeats (By simila [...]
Srgap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085712SLIT-ROBO Rho GTPase-activating protein 3; GTPase-activating protein for RAC1 and perhaps CDC42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons (By similarity).
Slc15a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085728Solute carrier family 15 member 1; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digest [...]
Srpk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085734SRSF protein kinase 2 C-terminal; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipep [...]
Khdc1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000085749KH homology domain-containing protein 1A; Has pro-apoptotic activity.
Mbnl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085763Muscleblind-like protein 2; Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) [...]
Atp2b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085775Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
Pkhd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085794Polycystic kidney and hepatic disease 1.
Xlr5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000085796X-linked lymphocyte-regulated protein 5C.
Slc38a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085799Sodium-coupled neutral amino acid transporter 1; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium [...]
Clec4b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085802Antigen presenting cell lectin-like receptor A1.
Gm14685 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085806Predicted gene 14685.
Clec4a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085816C-type lectin domain family 4, member a3.
Pi15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085826Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin (By similarity). May play a role in facial patterning during embryonic development (By si [...]
Magea10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085832Melanoma antigen family A, 10.
Nnat protein networkhttps://string-db.org/network/10090.ENSMUSP00000085836Neuronatin; May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system; Belong [...]
Blcap protein networkhttps://string-db.org/network/10090.ENSMUSP00000085849Bladder cancer-associated protein; May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B; Belongs t [...]
Dnase1l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085862Deoxyribonuclease-1-like 2; Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune rol [...]
Magi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085872Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2; Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion pr [...]
Xkr9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085900XK-related protein 9.
Fmr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085906Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of [...]
Myl9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085913Myosin regulatory light polypeptide 9; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. [...]
Smgc protein networkhttps://string-db.org/network/10090.ENSMUSP00000085915Submandibular gland protein C.
Pex26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085921Peroxisome assembly protein 26; Probably required for protein import into peroxisomes. Anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required fo [...]
Romo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085981Reactive oxygen species modulator 1; Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage (By [...]
Kif21a protein networkhttps://string-db.org/network/10090.ENSMUSP00000085985Kinesin-like protein KIF21A; Microtubule-binding motor protein probably involved in neuronal axonal transport. In vitro, has a plus-end directed motor activity; Belongs to the TRAFAC class myosin [...]
Arfgef1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085986Brefeldin A-inhibited guanine nucleotide-exchange protein 1; Promotes guanine-nucleotide exchange on ARF1 and ARF3. Promotes the activation of ARF1/ARF3 through replacement of GDP with GTP. Invol [...]
Srrm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085993Serine/arginine repetitive matrix protein 2; Required for pre-mRNA splicing as component of the spliceosome; Belongs to the CWC21 family.
Zic3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000085999Zinc finger protein ZIC 3; Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal G [...]
Wnk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086017Serine/threonine-protein kinase WNK1; Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an a [...]
Proca1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086022Protein PROCA1; Belongs to the PROCA1 family.
Htatsf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086027HIV Tat-specific factor 1 homolog; Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splici [...]
Ccdc87 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086028Coiled-coil domain-containing protein 87; Plays a role in spermatogenesis, where it is important for normal sperm head morphology. Also required for the acrosome reaction and thus normal male fer [...]
Mybl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086034Myb-related protein A; Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3'. Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expr [...]
Vxn protein networkhttps://string-db.org/network/10090.ENSMUSP00000086041Vexin; Required for neurogenesis in the neural plate and retina. Strongly cooperates with neural bHLH factors to promote neurogenesis ; Belongs to the vexin family.
Htr1d protein networkhttps://string-db.org/network/10090.ENSMUSP000000860525-hydroxytryptamine receptor 1D; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding cau [...]
Zfp945 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086074Zinc finger protein 945.
Smarcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086094SWI/SNF complex subunit SMARCC1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chroma [...]
Ncaph2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086095Condensin-2 complex subunit H2; Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishin [...]
Olfm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086112Olfactomedin-4; May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell dif [...]
Grk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086114Beta-adrenergic receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key reg [...]
Slxl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086118Slx-like 1.
Adam22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086139Disintegrin and metalloproteinase domain-containing protein 22; Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adh [...]
Zfp946 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086141Zinc finger protein 946.
Rtl8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000086157CAAX box 1 homolog A (Human).
Rtl8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000086158Retrotransposon Gag like 8A.
Zfp566 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086164Zinc finger protein 566.
Zfp948 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086166Zinc finger protein 948.
Zfp160 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086191Zinc finger protein 160.
Mapk11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086204Mitogen-activated protein kinase 11; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK11 is one of the four p38 MAPKs which play an [...]
Mapk12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086207Mitogen-activated protein kinase 12; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an [...]
Klra2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086252Killer cell lectin-like receptor 2; Receptor on natural killer (NK) cells for class I MHC.
Tmcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086285Transmembrane and coiled-coil domains protein 1; Endoplasmic reticulum membrane protein that promotes endoplasmic reticulum-associated endosome fission. Localizes to contact sites between the end [...]
Espnl protein networkhttps://string-db.org/network/10090.ENSMUSP00000086294Espin-like protein; Binds to but does not cross-link actin. Required for the formation and maintenance of inner ear hair cell stereocilia and staircase formation. Essential for normal hearing.
Bpifb9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000086311BPI fold-containing family B, member 9B.
Gtf2f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086312General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration w [...]
Bpifb9a protein networkhttps://string-db.org/network/10090.ENSMUSP00000086314Vomeromodulin.
Gramd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086321GRAM domain-containing protein 4; Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53 (By similarity). Inhibits TLR9 response to nucelic acids and regulates TLR9-media [...]
Tmem181a protein networkhttps://string-db.org/network/10090.ENSMUSP00000086333Transmembrane protein 181A.
Bpifb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086342BPI fold-containing family B member 3; May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to acc [...]
Bpifb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086347BPI fold-containing family B member 6.
Pkdrej protein networkhttps://string-db.org/network/10090.ENSMUSP00000086352Polycystic kidney disease and receptor for egg jelly-related protein; May have a central role in fertilization. May generate a Ca(2+) transporting channel directly involved in initiating the acro [...]
Lrch1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086363Leucine-rich repeat and calponin homology domain-containing protein 1; Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC [...]
Hrh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086383Histamine H1 receptor; In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal [...]
Snn protein networkhttps://string-db.org/network/10090.ENSMUSP00000086405Stannin; Plays a role in the toxic effects of organotins (By similarity). Plays a role in endosomal maturation.
Mas1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086409Proto-oncogene Mas; Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occu [...]
Fndc3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000086411Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis.
Tm9sf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086422Transmembrane 9 superfamily member 4; Associates with proteins harboring glycine-rich transmembrane domains and ensures their efficient localization to the cell surface. Belongs to the nonaspanin [...]
Nudt18 protein networkhttps://string-db.org/network/10090.ENSMUSP000000864508-oxo-dGDP phosphatase NUDT18; Mediates the hydrolysis of oxidized nucleoside diphosphate derivatives. Hydrolyzes 8-oxo-7,8-dihydroguanine (8-oxo-Gua)-containing deoxyribo- and ribonucleoside dip [...]
Map3k4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086459Mitogen-activated protein kinase kinase kinase 4; Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically [...]
H13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086460Minor histocompatibility antigen H13; Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the [...]
Rhox9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086462Reproductive homeobox on X chromosome 9.
Rhox4e protein networkhttps://string-db.org/network/10090.ENSMUSP00000086475Reproductive homeobox 4E.
Pde10a protein networkhttps://string-db.org/network/10090.ENSMUSP00000086485cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP a [...]
1110057P08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000086498RIKEN cDNA 1110057P08 gene.
Gm7735 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086499Predicted gene 7735.
1110025L11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000086505RIKEN cDNA 1110025L11 gene.
Gm10228 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086506Predicted gene 10228.
Gm10229 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086507Glycine tyrosine-rich hair keratin protein.
Tcf15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086511Transcription factor 15; May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm.
Cyp2d9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086530Cytochrome P450 2D9; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a var [...]
Nsfl1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000086542NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a ro [...]
Cenpm protein networkhttps://string-db.org/network/10090.ENSMUSP00000086560Centromere protein M; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segre [...]
Tnfrsf13c protein networkhttps://string-db.org/network/10090.ENSMUSP00000086564Tumor necrosis factor receptor superfamily member 13C; B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
Edem1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086565ER degradation-enhancing alpha-mannosidase-like protein 1; Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved [...]
Ccdc134 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086578Coiled-coil domain-containing protein 134; In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tu [...]
Zdhhc14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086589Probable palmitoyltransferase ZDHHC14; Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
Agtr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086592Type-2 angiotensin II receptor; Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
Cst7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086606Cystatin-F; Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system.
Rpl34 protein networkhttps://string-db.org/network/10090.ENSMUSP0000008661460S ribosomal protein L34; Component of the large ribosomal subunit.
Zfp120 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086615Zinc finger protein 120; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Cntn6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086623Contactin-6; Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTC [...]
Ppp2r2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000086640Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the [...]
Pnma2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086646Paraneoplastic antigen Ma2 homolog; Belongs to the PNMA family.
Csnka2ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000086692Casein kinase II subunit alpha'-interacting protein; May play a role in chromatin regulation of male germ cells.
Uba3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086701NEDD8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter lin [...]
Arl13b protein networkhttps://string-db.org/network/10090.ENSMUSP00000086703ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomp [...]
Tafa4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086710Chemokine-like protein TAFA-4; Modulates injury-induced and chemical pain hypersensitivity. Ligand of FPR1, can chemoattract macrophages, promote phagocytosis and increase ROS release.
Olfr658 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086711Olfactory receptor.
Npcd protein networkhttps://string-db.org/network/10090.ENSMUSP00000086714Neuronal pentraxin chromo domain.
Usp9x protein networkhttps://string-db.org/network/10090.ENSMUSP00000086716Probable ubiquitin carboxyl-terminal hydrolase FAF-X; Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulat [...]
Magi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086730Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1; May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating [...]
Gpr15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086731G-protein coupled receptor 15; Probable chemokine receptor; Belongs to the G-protein coupled receptor 1 family.
Col8a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086745Collagen alpha-1(VIII) chain; Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the en [...]
Fgd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086748FYVE, RhoGEF and PH domain-containing protein 5; Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF- induced CDC42 acti [...]
Prss55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086752Serine protease 55; Probable serine protease; Belongs to the peptidase S1 family.
Senp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086779Sentrin-specific protease 7; Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low effici [...]
Ssxb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086792Synovial sarcoma, X member B, breakpoint 3.
Lgals1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086795Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein [...]
Pdxp protein networkhttps://string-db.org/network/10090.ENSMUSP00000086796Pyridoxal phosphate phosphatase; Protein serine phosphatase that dephosphorylates 'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependen [...]
Sacs protein networkhttps://string-db.org/network/10090.ENSMUSP00000086816Sacsin; Co-chaperone which acts as a regulator of the Hsp70 chaperone machinery and may be involved in the processing of other ataxia-linked proteins.
Il2rb protein networkhttps://string-db.org/network/10090.ENSMUSP00000086820Interleukin-2 receptor subunit beta; Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in associatio [...]
Gm11808 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086852Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an iso [...]
Apol10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000086890Apolipoprotein L 10B.
Apol7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000086894Apolipoprotein L 7b.
Zdhhc20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086900Palmitoyltransferase ZDHHC20; Catalyzes palmitoylation of Cys residues on target proteins. Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the durati [...]
Il17d protein networkhttps://string-db.org/network/10090.ENSMUSP00000086921Interleukin 17D.
Isy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086923Pre-mRNA-splicing factor ISY1 homolog; Component of the spliceosome C complex required for the selective processing of microRNAs (miRNAs) during embryonic stem cell differentiation. Required for [...]
Ap5s1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086933AP-5 complex subunit sigma-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport.
Cenpb protein networkhttps://string-db.org/network/10090.ENSMUSP00000086938Major centromere autoantigen B; Interacts with centromeric heterochromatin in chromosomes and binds to a specific 17 bp subset of alphoid satellite DNA, called the CENP-B box. May organize arrays [...]
Aak1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086948AP2-associated protein kinase 1; Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP [...]
Gzme protein networkhttps://string-db.org/network/10090.ENSMUSP00000086978Granzyme E; This enzyme is probably necessary for target cell lysis in cell-mediated immune responses; Belongs to the peptidase S1 family. Granzyme subfamily.
Cma2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086984Mast cell protease 10; Belongs to the peptidase S1 family.
Snrpg protein networkhttps://string-db.org/network/10090.ENSMUSP00000086987Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, [...]
Ddrgk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000086988DDRGK domain-containing protein 1; Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may [...]
Noto protein networkhttps://string-db.org/network/10090.ENSMUSP00000087006Homeobox protein notochord; Transcription factor that controls node morphogenesis. Acts downstream of both FOXA2 and Brachyury (T) during notochord development. Is essential for cilia formation i [...]
Pced1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000087009PC-esterase domain-containing protein 1A; Belongs to the PC-esterase family.
Cd86 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087047T-lymphocyte activation antigen CD86; Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a cr [...]
Csta3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087054Cystatin A family member 3.
Tlx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087069T-cell leukemia homeobox protein 2; Transcription activator that binds DNA elements with the consensus sequence 5'-CGGTAATTGG-3'. Binds DNA via its homeobox. Required for normal cell death of ent [...]
Htra2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087073Serine protease HTRA2, mitochondrial; Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and [...]
Dok1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087079Docking protein 1; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be [...]
Reg3d protein networkhttps://string-db.org/network/10090.ENSMUSP00000087096Regenerating islet-derived 3 delta.
Mapk15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087098Mitogen-activated protein kinase 15; Atypical MAPK protein that regulates several process such as autophagy, ciliogenesis, protein trafficking/secretion and genome integrity, in a kinase activity [...]
Astl protein networkhttps://string-db.org/network/10090.ENSMUSP00000087102Astacin-like metalloendopeptidase; Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease f [...]
Rubcn protein networkhttps://string-db.org/network/10090.ENSMUSP00000087114Run domain Beclin-1-interacting and cysteine-rich domain-containing protein; Inhibits PIK3C3 activity; under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophag [...]
Mat2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000087118S-adenosylmethionine synthase isoform type-2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: [...]
Mmp14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087119Matrix metalloproteinase-14; Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and [...]
Chrac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087197Chromatin accessibility complex protein 1; Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remode [...]
Trappc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087202Trafficking protein particle complex subunit 9; Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May p [...]
Rnase13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087203Probable inactive ribonuclease-like protein 13; Does not exhibit any ribonuclease activity; Belongs to the pancreatic ribonuclease family.
Cep152 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087208Centrosomal protein of 152 kDa; Necessary for centrosome duplication; the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recr [...]
Plaat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087257Phospholipase A and acyltransferase 1; Exhibits both phospholipase A1/2 and acyltransferase activities (By similarity). Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calciu [...]
Gmnc protein networkhttps://string-db.org/network/10090.ENSMUSP00000087269Geminin coiled-coil domain-containing protein 1; Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2-dependent recruitment of CDC45L ont [...]
Mageb16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087292Melanoma-associated antigen B16.
Fam13a protein networkhttps://string-db.org/network/10090.ENSMUSP00000087304Protein FAM13A.
Mcc protein networkhttps://string-db.org/network/10090.ENSMUSP00000087318Mutated in colorectal cancers.
Masp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087327Mannan-binding lectin serine protease 1 heavy chain; Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar [...]
Dgkg protein networkhttps://string-db.org/network/10090.ENSMUSP00000087371Diacylglycerol kinase gamma.
Mfap1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000087372Microfibrillar-associated protein 1A.
Slc44a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087394Choline transporter-like protein 5.
Gch1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087405GTP cyclohydrolase 1; May positively regulate nitric oxide synthesis in endothelial cells. May be involved in dopamine synthesis. May modify pain sensitivity and persistence.
Calcoco2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087407Calcium-binding and coiled-coil domain-containing protein 2; Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation (By similarity). Acts as an effector pr [...]
Hnrnpa2b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087453Heterogeneous nuclear ribonucleoproteins A2/B1; Heterogeneous nuclear ribonucleoprotein (hnRNP) that associates with nascent pre-mRNAs, packaging them into hnRNP particles. The hnRNP particle arr [...]
Itgb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087457Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydrox [...]
Osbpl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087473Oxysterol-binding protein-related protein 3; Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes. Can bind to the ER membrane protein VAPA an [...]
Aard protein networkhttps://string-db.org/network/10090.ENSMUSP00000087479Alanine and arginine-rich domain-containing protein.
Tmem87a protein networkhttps://string-db.org/network/10090.ENSMUSP00000087500Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN).
Sybu protein networkhttps://string-db.org/network/10090.ENSMUSP00000087511Syntabulin; Part of a kinesin motor-adapter complex that is critical for the anterograde axonal transport of active zone components and contributes to activity-dependent presynaptic assembly duri [...]
1700123L14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000087515RIKEN cDNA 1700123L14 gene.
Gimap4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087524GTPase IMAP family member 4; During thymocyte development, may play a role in the regulation of apoptosis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc3 [...]
Pla2g4e protein networkhttps://string-db.org/network/10090.ENSMUSP00000087525Cytosolic phospholipase A2 epsilon; Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position.
Gnb1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000087544Guanine nucleotide-binding protein subunit beta-like protein 1.
Arvcf protein networkhttps://string-db.org/network/10090.ENSMUSP00000087562Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog; Involved in protein-protein interactions at adherens junctions.
Gbp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087587Guanylate-binding protein 5; As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microb [...]
Btd protein networkhttps://string-db.org/network/10090.ENSMUSP00000087608Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.
Ncald protein networkhttps://string-db.org/network/10090.ENSMUSP00000087611Neurocalcin-delta; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions (By similarity). Belongs to the recoverin family.
Adh7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087633All-trans-retinol dehydrogenase [NAD(+)] ADH7; Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, aldehyde and omega-hydroxy fatty acids and their derivatives. Oxidizes preferen [...]
Zfyve19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087636Abscission/NoCut checkpoint regulator; Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolu [...]
Dnajb14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087641DnaJ homolog subfamily B member 14; Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded prot [...]
Sema3g protein networkhttps://string-db.org/network/10090.ENSMUSP00000087643Semaphorin-3G; Has chemorepulsive activities for sympathetic axons. Ligand of NRP2.
Hic2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087656Hypermethylated in cancer 2 protein; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family. Hic subfamily.
Nt5dc2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000876805'-nucleotidase domain-containing 2.
Bmf protein networkhttps://string-db.org/network/10090.ENSMUSP00000087686Bcl-2-modifying factor; May play a role in apoptosis; Belongs to the Bcl-2 family.
March6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087694E3 ubiquitin-protein ligase MARCHF6; E3 ubiquitin-protein ligase that promotes 'Lys-48'-linked ubiquitination of target proteins, leading to their proteasomal degradation. Promotes ubiquitination [...]
Slc37a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087709Sugar phosphate exchanger 3.
Sgms2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087713Phosphatidylcholine:ceramide cholinephosphotransferase 2; Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, [...]
Trio protein networkhttps://string-db.org/network/10090.ENSMUSP00000087714Triple functional domain protein; Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases. Involved in coordinating actin remodeling, which is necessary for cell migration and growth ( [...]
Gm4841 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087727Interferon-gamma-inducible GTPase Ifgga3 protein.
Actc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087736Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; [...]
Gjd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087742Gap junction delta-2 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a [...]
Efcab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087744EF-hand calcium-binding domain-containing protein 1.
Marf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087770Meiosis regulator and mRNA stability factor 1; Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which i [...]
Erc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087773ERC protein 2; Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May [...]
Dytn protein networkhttps://string-db.org/network/10090.ENSMUSP00000087787Dystrotelin.
Olfr1279 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087801Olfactory receptor.
Asb14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087810Ankyrin repeat and SOCS box protein 14; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquit [...]
Rai14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087815Ankycorbin; Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhe [...]
Usp53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087857Inactive ubiquitin carboxyl-terminal hydrolase 53; Tight junction-associated protein that is involved in the survival of auditory hair cells and hearing. Maybe by modulating the barrier propertie [...]
Pax6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087870Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic is [...]
Dlg5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087879Disks large homolog 5; Acts as a regulator of the Hippo signaling pathway. Negatively regulates the Hippo signaling pathway by mediating the interaction of MARK3 with STK3/4, bringing them togeth [...]
Utp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087896Something about silencing protein 10; Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain. Belongs to the SAS10 family.
Cd59b protein networkhttps://string-db.org/network/10090.ENSMUSP00000087912CD59B glycoprotein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporatio [...]
Camk2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000087925Calcium/calmodulin-dependent protein kinase type II subunit beta; Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, [...]
Fyb protein networkhttps://string-db.org/network/10090.ENSMUSP00000087947FYN-binding protein 1; Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton (By simila [...]
Cdc14a protein networkhttps://string-db.org/network/10090.ENSMUSP00000087950Dual specificity protein phosphatase CDC14A; Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early [...]
Myoz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087955Myozenin-1; Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin [...]
Gpr88 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087959Probable G-protein coupled receptor 88; Probable G-protein coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional [...]
Ehf protein networkhttps://string-db.org/network/10090.ENSMUSP00000087961ETS homologous factor; Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation. May act as a repressor for a specific subset of ETS/AP-1-res [...]
Fam149b protein networkhttps://string-db.org/network/10090.ENSMUSP00000087985Protein FAM149B1.
Gcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000087997GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure.
Zfp597 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088009Zinc finger protein 597.
Atp5g1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088029ATP synthase F(0) complex subunit C1, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the [...]
Nr1d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088031Nuclear receptor subfamily 1 group D member 2; Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex tr [...]
Tmem167b protein networkhttps://string-db.org/network/10090.ENSMUSP00000088035Protein kish-B; Involved in the early part of the secretory pathway. Belongs to the KISH family.
Celsr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088046Cadherin EGF LAG seven-pass G-type receptor 2; Receptor that may have an important role in cell/cell signaling during nervous system formation.
Cry2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088047Cryptochrome-2; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes thro [...]
Mybphl protein networkhttps://string-db.org/network/10090.ENSMUSP00000088051Myosin-binding protein H-like; Belongs to the immunoglobulin superfamily. MyBP family.
Ptprz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088056Receptor-type tyrosine-protein phosphatase zeta; Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal d [...]
Psma5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088057Proteasome subunit alpha type-5; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles w [...]
Phf21a protein networkhttps://string-db.org/network/10090.ENSMUSP00000088074PHD finger protein 21A; Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE s [...]
Atxn7l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088085Ataxin-7-like protein 1.
Cttnbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088089Cortactin-binding protein 2; Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance.
Harbi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088098Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity (By similarity). Belongs to the HARBI1 family.
Kcna10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088118Potassium voltage-gated channel subfamily A member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the vol [...]
Rap1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000088174Ras-related protein Rap-1A; Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with R [...]
Ddx20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088176Probable ATP-dependent RNA helicase DDX20; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, pla [...]
Syt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088196Synaptotagmin-6; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of ves [...]
Olfr1188 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088202Olfactory receptor.
Olfr1145 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088209Olfactory receptor 1145.
Olfr1143 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088210Olfactory receptor.
Olfr152 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088211Olfactory receptor.
Ampd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088217AMP deaminase 1; AMP deaminase plays a critical role in energy metabolism.
Slc43a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088227Solute carrier family 43 member 3; Putative transporter.
Ypel4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088231Protein yippee-like 4; Belongs to the yippee family.
Hmgcs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088249Hydroxymethylglutaryl-CoA synthase, mitochondrial; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Pde4dip protein networkhttps://string-db.org/network/10090.ENSMUSP00000088254Myomegalin; Functions as an anchor sequestering components of the cAMP- dependent pathway to Golgi and/or centrosomes (By similarity).
Acp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088263Lysophosphatidic acid phosphatase type 6; Hydrolyzes lysophosphatidic acid (LPA) containing a medium length fatty acid chain to the corresponding monoacylglycerol. Has highest activity with lysop [...]
Gja5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088264Gap junction alpha-5 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a [...]
Ppp1r1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000088265Protein phosphatase 1 regulatory subunit 1C; May increase cell susceptibility to TNF-induced apoptosis.
Zfp385b protein networkhttps://string-db.org/network/10090.ENSMUSP00000088271Zinc finger protein 385B; May play a role in p53/TP53-mediated apoptosis.
H2ac7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088281H2A clustered histone 7.
H2ac13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088285H2A clustered histone 13.
H2bc21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088287Histone H2B type 2-E; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
H2ac20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088288Histone H2A type 2-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
Otud7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000088291OTU domain-containing protein 7B; Negative regulator of the non-canonical NF-kappa-B pathway that acts by mediating deubiquitination of TRAF3, an inhibitor of the NF-kappa-B pathway, thereby acti [...]
Rprd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088297Regulation of nuclear pre-mRNA domain-containing protein 2.
Scrn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088320Secernin-3; Belongs to the peptidase C69 family. Secernin subfamily.
Sp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088322Transcription factor Sp9; Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgro [...]
Gm128 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088324Protein MENT; Involved in control of cellular proliferation. Onconcogenic modifier contributing to the tumor suppressor function of DNMT3B.
Sema6c protein networkhttps://string-db.org/network/10090.ENSMUSP00000088333Semaphorin-6C; May be a stop signal for the dorsal root ganglion neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neur [...]
Map3k20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088334Mitogen-activated protein kinase kinase kinase 20; Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Part of a signaling cascade that [...]
Rapgef4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088336Rap guanine nucleotide exchange factor 4; Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involve [...]
Pgap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088337Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 [...]
Selenbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088349Methanethiol oxidase; Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved [...]
Selenbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088358Selenium-binding protein 2; Selenium- and acetaminophen-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein trans [...]
Gm5773 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088366TD and POZ domain-containing protein 2.
Hrnr protein networkhttps://string-db.org/network/10090.ENSMUSP00000088369Hornerin; Component of the epidermal cornified cell envelopes; Belongs to the S100-fused protein family.
Lce3f protein networkhttps://string-db.org/network/10090.ENSMUSP00000088375Late cornified envelope 3F.
Lce1i protein networkhttps://string-db.org/network/10090.ENSMUSP00000088379Late cornified envelope 1I.
Lce1e protein networkhttps://string-db.org/network/10090.ENSMUSP00000088380Late cornified envelope 1E.
Rusc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088447RUN and SH3 domain-containing protein 1; Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed t [...]
Acvr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088453Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate [...]
Dap3 protein networkhttps://string-db.org/network/10090.ENSMUSP0000008845628S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death. Belongs to the mitochondrion-specific ribosomal protein mS29 family.
Ermn protein networkhttps://string-db.org/network/10090.ENSMUSP00000088458Ermin; Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May p [...]
Bcan protein networkhttps://string-db.org/network/10090.ENSMUSP00000088491Brevican core protein; May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain [...]
Nes protein networkhttps://string-db.org/network/10090.ENSMUSP00000088493Nestin; Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribut [...]
Fcrls protein networkhttps://string-db.org/network/10090.ENSMUSP00000088508Fc receptor-like S, scavenger receptor.
Tcl1b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088512Protein TCL1B3; Belongs to the TCL1 family.
Dab2ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000088532Disabled homolog 2-interacting protein; Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several pr [...]
Map9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088535Microtubule-associated protein 9; Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing inter [...]
Ralgps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088563Ras-specific guanine nucleotide-releasing factor RalGPS1; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeleton organization.
Rraga protein networkhttps://string-db.org/network/10090.ENSMUSP00000088591Ras-related GTP-binding protein A; Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling casc [...]
Dnm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088618Dynamin-1; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. [...]
Phyhd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088663Phytanoyl-CoA dioxygenase domain-containing protein 1; Has alpha-ketoglutarate-dependent dioxygenase activity. Does not show detectable activity towards fatty acid CoA thioesters. Is not expected [...]
Frem2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088670FRAS1-related extracellular matrix protein 2; Extracellular matrix protein required for maintenance of the integrity of the skin epithelium and for maintenance of renal epithelia (By similarity). [...]
Urm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088676Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in [...]
Sry protein networkhttps://string-db.org/network/10090.ENSMUSP00000088717Sex-determining region Y protein; Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing t [...]
H2al1j protein networkhttps://string-db.org/network/10090.ENSMUSP00000088719Histone H2A; Belongs to the histone H2A family.
Slc25a31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088723ADP/ATP translocase 4; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming proces [...]
Intu protein networkhttps://string-db.org/network/10090.ENSMUSP00000088725Protein inturned; Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of [...]
Usp9y protein networkhttps://string-db.org/network/10090.ENSMUSP00000088727Ubiquitin-specific peptidase 9, Y chromosome; Belongs to the peptidase C19 family.
Ddx3y protein networkhttps://string-db.org/network/10090.ENSMUSP00000088729ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway.
Eif2s3y protein networkhttps://string-db.org/network/10090.ENSMUSP00000088736Eukaryotic translation initiation factor 2 subunit 3, Y-linked; As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eI [...]
Arl15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088740ADP-ribosylation factor-like protein 15; Belongs to the small GTPase superfamily. Arf family.
Qrfpr protein networkhttps://string-db.org/network/10090.ENSMUSP00000088768Pyroglutamylated RF-amide peptide receptor; Receptor for the orexigenic neuropeptide QRFP. The activity of this receptor is mediated by G proteins that modulate adenylate cyclase activity and int [...]
Adamtsl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088774ADAMTS-like protein 2.
Atp11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000088779Probable phospholipid-transporting ATPase IH; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the out [...]
Sec16a protein networkhttps://string-db.org/network/10090.ENSMUSP00000088796Protein transport protein Sec16A; Acts as a molecular scaffold that plays a key role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic ret [...]
Mfn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088801Mitofusin-1; Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Membrane clustering requires GTPase activity (By similarity). It may involve a major rearrangem [...]
Slc7a14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088803Probable cationic amino acid transporter; May be involved in arginine transport.
Lcn11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088822Lipocalin 11; Belongs to the calycin superfamily. Lipocalin family.
Prnp protein networkhttps://string-db.org/network/10090.ENSMUSP00000088833Major prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May pr [...]
Insr protein networkhttps://string-db.org/network/10090.ENSMUSP00000088837Insulin receptor subunit alpha; Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, includ [...]
Cdk7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088845Cyclin-dependent kinase 7; Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. Cyclin-dependent kinases (CDKs) are activated by the binding [...]
Sirpb1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000088869Signal-regulatory protein beta 1B.
1700008P02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000088923RIKEN cDNA 1700008P02 gene.
Sumo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088935Small ubiquitin-related modifier 1; Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its s [...]
Arsb protein networkhttps://string-db.org/network/10090.ENSMUSP00000088964Arylsulfatase B; Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (By similarity). Involved in the regulation of cell adhesion, cell migration and invasion in [...]
Skida1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000088982SKI/DACH domain-containing protein 1; Belongs to the DACH/dachshund family.
Cubn protein networkhttps://string-db.org/network/10090.ENSMUSP00000089009Cubilin; Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake. Acts together with LRP2 to mediate endocytosis of high-density lipoprotein [...]
Zscan4-ps2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089014Zinc finger and SCAN domain containing 4, pseudogene 2.
Nr2f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089036COUP transcription factor 1; Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiati [...]
Stxbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089051Syntaxin-binding protein 1; Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins (By similarity). Essential for neurotransmission an [...]
Zdhhc11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089075Probable palmitoyltransferase ZDHHC11.
Frmd4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000089079FERM domain-containing protein 4A; Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4B in epithelia [...]
Srd5a1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000890973-oxo-5-alpha-steroid 4-dehydrogenase 1; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a cent [...]
Rslcan18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089111Regulator of sex-limitation candidate 18.
Cntnap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089140Contactin-associated protein-like 3.
Aopep protein networkhttps://string-db.org/network/10090.ENSMUSP00000089148Aminopeptidase O; Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a [...]
4930486L24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000089157Testin-1; Belongs to the peptidase C1 family.
Gkap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089169G kinase-anchoring protein 1; Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is re [...]
Wnk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089212Serine/threonine-protein kinase WNK2; Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an a [...]
Lrrtm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089225Leucine-rich repeat transmembrane neuronal protein 2; Involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA rece [...]
Snrnp48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089230U11/U12 small nuclear ribonucleoprotein 48 kDa protein; Likely involved in U12-type 5' splice site recognition.
Gpr31b protein networkhttps://string-db.org/network/10090.ENSMUSP0000008923712-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor; High-affinity receptor for 12-(S)-hydroxy-5,8,10,14- eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secr [...]
Pramel4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089265Preferentially-expressed antigen in melanoma-like 4.
Prl6a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089269Prolactin-6A1.
Tdpoz7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089284TD and POZ domain-containing protein 5.
H3c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089293H3 clustered histone 1.
H3c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089295H3 clustered histone 2.
Hfe protein networkhttps://string-db.org/network/10090.ENSMUSP00000089298Hereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.
H2bc15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089301Histone H2B type 1-F/J/L; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Hi [...]
Vmn1r194 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089331Vomeronasal type-1 receptor.
H2ac11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089335H2A clustered histone 11.
H2ac12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089336H2A clustered histone 12.
Hist1h2ao protein networkhttps://string-db.org/network/10090.ENSMUSP00000089339Histone cluster 1, H2ao.
Hist1h2bq protein networkhttps://string-db.org/network/10090.ENSMUSP00000089343Histone H2B; Belongs to the histone H2B family.
Hist1h2an protein networkhttps://string-db.org/network/10090.ENSMUSP00000089345Histone cluster 1, H2an.
H3c3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089346H3 clustered histone 3.
H2bc13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089350H2B clustered histone 13.
Nme8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089358Thioredoxin domain-containing protein 3; Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (F [...]
Tshz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089388Teashirt homolog 1; Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential).
A630073D07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000089395RIKEN cDNA A630073D07 gene.
Akr1e1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000894591,5-anhydro-D-fructose reductase; Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D- fructose (AF) to 1,5-anhydro-D-glucitol; Belongs to the aldo/keto reductase family.
Mapk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089462Mitogen-activated protein kinase 4; Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still uncle [...]
Mex3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000089463RNA-binding E3 ubiquitin-protein ligase MEX3C; RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms, modulating levels of some mRNAs by promoting their degradation i [...]
Net1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089464Neuroepithelial cell-transforming gene 1 protein; Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway. Stimulates genotoxic str [...]
Zfp987 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089493Predicted gene, OTTMUSG00000010173.
Zfp942 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089494Zinc finger protein 942.
Hmgxb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089498HMG box domain-containing 3.
Ctxn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089507Cortexin-3.
Prdm6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089513Putative histone-lysine N-methyltransferase PRDM6; Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from diffe [...]
Sh3bp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089517SH3 domain-binding protein 5; Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25 (By similarity). Inhibits the auto- and transphosphorylation activity of [...]
Rbm27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089540RNA-binding protein 27.
Polr3gl protein networkhttps://string-db.org/network/10090.ENSMUSP00000089544DNA-directed RNA polymerase III subunit RPC7-like; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific per [...]
Pcdhga9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089555Protocadherin gamma subfamily A, 9.
Olfr768 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089619Olfactory receptor.
Olfr9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089622Olfactory receptor 9; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Rbms2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089664RNA-binding motif, single-stranded-interacting protein 2.
Naca protein networkhttps://string-db.org/network/10090.ENSMUSP00000089680Nascent polypeptide-associated complex subunit alpha, muscle-specific form; Cardiac- and muscle-specific transcription factor. May act to regulate the expression of genes involved in the developm [...]
Rdh16f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089691Cis-retinol/3alpha hydroxysterol short-chain dehydrogenase-like protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Lama3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089703Laminin subunit alpha-3; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development [...]
Stat6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089708Signal transducer and transcription activator 6; Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated si [...]
Mcidas protein networkhttps://string-db.org/network/10090.ENSMUSP00000089721Multicilin; Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required fo [...]
Usp14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089728Ubiquitin carboxyl-terminal hydrolase 14; Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin [...]
Epc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089758Enhancer of polycomb homolog 2; May play a role in transcription or DNA repair. Belongs to the enhancer of polycomb family.
Piezo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089777Piezo-type mechanosensitive ion channel component 1; Pore-forming subunit of a mechanosensitive non-specific cation channel. Generates currents characterized by a linear current- voltage relation [...]
Msrb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089781Methionine-R-sulfoxide reductase B3, mitochondrial; Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine.
Rnpc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089792RNA-binding region-containing protein 3; Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1 [...]
Col11a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089793Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils; Belongs to the fibrillar collagen family.
Lyz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089800Lysozyme C-1; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Lyz1 [...]
Lyz2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089801Lysozyme C-2; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Lyz2 [...]
Ptprb protein networkhttps://string-db.org/network/10090.ENSMUSP00000089805Receptor-type tyrosine-protein phosphatase beta; Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential fo [...]
Tmem19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089808Transmembrane protein 19; Belongs to the TMEM19 family.
Ccdc38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089860Coiled-coil domain-containing protein 38.
Mbd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089948Methyl-CpG-binding domain protein 3; Acts as transcriptional repressor and plays a role in gene silencing. Does not bind DNA by itself. Binds to DNA with a preference for sites containing methyla [...]
Zfp750 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089951Zinc finger protein 750; Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late [...]
Dazap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089958DAZ-associated protein 1; RNA-binding protein, which may be required during spermatogenesis.
Plppr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000089979Phospholipid phosphatase-related protein type 3.
Tspear protein networkhttps://string-db.org/network/10090.ENSMUSP00000090020Thrombospondin-type laminin G domain and EAR repeat-containing protein; Plays a critical role in tooth and hair follicle morphogenesis through regulation of the Notch signaling pathway. May play [...]
Krtap12-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090024Keratin associated protein 12-1.
Gm10272 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090025Predicted gene 10272.
Enpp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090027Ectonucleotide pyrophosphatase/phosphodiesterase 7.
Srsf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090059Serine/arginine-rich splicing factor 2; Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal compone [...]
2610028H24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000090061RIKEN cDNA 2610028H24 gene.
Ccdc153 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090082Coiled-coil domain-containing protein 153; Belongs to the UPF0610 family.
Tfam protein networkhttps://string-db.org/network/10090.ENSMUSP00000090086Transcription factor A, mitochondrial; Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Component of the mitochondrial transcription initi [...]
Slc16a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090102Monocarboxylate transporter 6; Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-cha [...]
Cd300ld3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090116CMRF35-like molecule 3; Acts as an activating receptor inducing cytokine production in mast cells. Can act as a positive regulator of TLR9 signaling in macrophages, leading to enhanced production [...]
Cd300c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090121CMRF-35-like molecule 4; Acts as an activating receptor in mast cells and macrophages. Belongs to the CD300 family.
Cd300c protein networkhttps://string-db.org/network/10090.ENSMUSP00000090123CMRF35-like molecule 6.
Vps26a protein networkhttps://string-db.org/network/10090.ENSMUSP00000090130Vacuolar protein sorting-associated protein 26A; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective [...]
Adamts14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090143A Disintegrin-like and metallopeptidase (Reprolysin type) with thrombospondin type 1 motif, 14.
Vmn2r111 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090148Vomeronasal 2, receptor 111.
Smurf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090177E3 ubiquitin-protein ligase SMURF2; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquiti [...]
Gm10324 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090190Predicted gene 10324.
Slc16a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090227Monocarboxylate transporter 10; Sodium-independent transporter that mediates the uptake of aromatic acids. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epith [...]
Ccdc43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090230Coiled-coil domain-containing protein 43.
Src protein networkhttps://string-db.org/network/10090.ENSMUSP00000090237Neuronal proto-oncogene tyrosine-protein kinase Src; Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune [...]
Marcks protein networkhttps://string-db.org/network/10090.ENSMUSP00000090245Myristoylated alanine-rich C-kinase substrate; MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F [...]
Pcgf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090277Polycomb group RING finger protein 1; Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as [...]
Aup1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090281Ancient ubiquitous protein 1; May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome; [...]
Rspo3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090287R-spondin-3; Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors, which acts as a key regulator of angiogenesis. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6 [...]
9330159F19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000090291RIKEN cDNA 9330159F19 gene.
Soga3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090293Protein SOGA3.
Lama2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090304Laminin subunit alpha-2; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development [...]
Med23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090316Mediator of RNA polymerase II transcription subunit 23; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Taar8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000090324Trace amine-associated receptor 8b; Orphan olfactory receptor specific for trace amines. Belongs to the G-protein coupled receptor 1 family.
Taar7e protein networkhttps://string-db.org/network/10090.ENSMUSP00000090326Trace amine-associated receptor 7e; Orphan olfactory receptor specific for trace amines. Belongs to the G-protein coupled receptor 1 family.
Taar7d protein networkhttps://string-db.org/network/10090.ENSMUSP00000090327Trace amine-associated receptor 7d; Orphan olfactory receptor specific for trace amines. Belongs to the G-protein coupled receptor 1 family.
Taar7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000090328Trace amine-associated receptor 7b; Orphan olfactory receptor specific for trace amines. Belongs to the G-protein coupled receptor 1 family.
Taar5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090329Trace amine-associated receptor 5; Olfactory receptor specific for trimethylamine, a trace amine enriched in the urine of male mice, playing a role in social behavior. Trimethylamine is present a [...]
Taar4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090330Trace amine-associated receptor 4; Olfactory receptor specific for 2-phenylethylamine, a trace amine present at high concentration in the urine of carnivore species, playing a key role in fear an [...]
Eya4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090335Eyes absent homolog 4; Tyrosine phosphatase that specifically dephosphorylates 'Tyr- 142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repai [...]
Ttc25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090355Tetratricopeptide repeat protein 25; Required for the docking of the outer dynein arm to cilia, hence plays an essential role in cilia motility.
Nt5c3b protein networkhttps://string-db.org/network/10090.ENSMUSP000000903607-methylguanosine phosphate-specific 5'-nucleotidase; Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate. The specific activity for m(7 [...]
Gm11559 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090367Predicted gene 11559.
4930572O03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000090370RIKEN cDNA 4930572O03 gene.
Krtap3-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090373Keratin-associated protein 3-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Krtap3-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090374Keratin associated protein 3-3.
5430403G16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000090395RIKEN cDNA 5430403G16 gene.
Dlx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090443Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less home [...]
Tmem100 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090464Transmembrane protein 100; Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor- dependent signaling pathway upon stimulation [...]
Msi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090470RNA-binding protein Musashi homolog 2; RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cel [...]
Synrg protein networkhttps://string-db.org/network/10090.ENSMUSP00000090510Synergin gamma; May play a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN). May act by linking the adapter protein complex AP-1 to other proteins (By similarity).
Wfdc17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090511Activated macrophage/microglia WAP domain protein.
Fbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090564Fructose-1,6-bisphosphatase 1; Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenes [...]
Cacng7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090567Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and ga [...]
Ankrd13b protein networkhttps://string-db.org/network/10090.ENSMUSP00000090568Ankyrin repeat domain-containing protein 13B; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regul [...]
Cluh protein networkhttps://string-db.org/network/10090.ENSMUSP00000090593Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in th [...]
Spata22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090602Spermatogenesis-associated protein 22; Meiosis-specific protein required for homologous recombination in meiosis I.
Gm4952 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090607Glycine N-acyltransferase-like protein; Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Can conjugate a multitude of substrates to form a variety of N-a [...]
Camkk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090613Calcium/calmodulin-dependent protein kinase kinase 1; Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular p [...]
Spns3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090617Protein spinster homolog 3; Sphingolipid transporter.
Ahnak protein networkhttps://string-db.org/network/10090.ENSMUSP00000090633AHNAK nucleoprotein (desmoyokin).
Asgr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090637Asialoglycoprotein receptor 1; Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor rec [...]
Dynlt1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000090644Dynein light chain Tctex-type 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to a [...]
Cntrob protein networkhttps://string-db.org/network/10090.ENSMUSP00000090651Centrobin; Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis (By similarity).
Myh7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000090672Myosin-7B; Involved in muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Sco1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090673Protein SCO1 homolog, mitochondrial; Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Not required for the synthesis of MT-CO2/COX2 but plays [...]
Fam83g protein networkhttps://string-db.org/network/10090.ENSMUSP00000090697Protein FAM83G; May regulate the bone morphogenetic proteins (BMP) pathway. Belongs to the FAM83 family.
Slc47a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090710Multidrug and toxin extrusion protein 2; Solute transporter for tetraethylammonium (TEA), cimetidine, choline, procainamide, cimetidine, quinidine, guanidine, N- methylnicotinamide (NMN). Respons [...]
Capn9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090717Calpain-9; Calcium-regulated non-lysosomal thiol-protease.
Rab4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000090727Ras-related protein Rab-4B; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.
Gas8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090730Dynein regulatory complex subunit 4; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the dis [...]
Pabpn1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000090747Embryonic polyadenylate-binding protein 2; Binds the poly(A) tail of mRNA.
Taf1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000090789TATA box-binding protein-associated factor RNA polymerase I subunit C; Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation comple [...]
Dnaaf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090790Dynein assembly factor 1, axonemal; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms (By similarity). Involve [...]
Medag protein networkhttps://string-db.org/network/10090.ENSMUSP00000090798Mesenteric estrogen-dependent adipogenesis protein; Involved in processes that promote adipocyte differentiation, lipid accumulation, and glucose uptake in mature adipocytes.
Adamts18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090801A disintegrin and metalloproteinase with thrombospondin motifs 18.
Clk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090820Dual specificity protein kinase CLK4; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the sp [...]
9930111J21Rik2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090839Interferon-gamma-inducible GTPase Ifggb1 protein.
Ap1g1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090844AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP co [...]
Atxn1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000090850Ataxin-1-like; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, alon [...]
Gm12166 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090857Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.
Smco1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090873Single-pass membrane and coiled-coil domain-containing protein 1.
Spdl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090882Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle [...]
Dock2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090884Dedicator of cytokinesis protein 2; Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as [...]
Pard6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000090886Partitioning defective 6 homolog alpha; Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. A [...]
Hba-a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090895Hemoglobin subunit alpha; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family.
Hba-a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090897Hemoglobin alpha, adult chain 1.
Ces3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000090909Carboxylesterase 3B; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family.
Ces3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000090910Carboxylesterase 3A; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family.
Mtif2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090926Translation initiation factor IF-2, mitochondrial; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes [...]
Sertad2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090981SERTA domain-containing protein 2; Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivato [...]
Spred2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000090987Sprouty-related, EVH1 domain-containing protein 2; Negatively regulates Ras signaling pathways and downstream activation of MAP kinases.
Irx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091002Iroquois-class homeodomain protein IRX-3; Transcription factor involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the [...]
Grb10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091011Growth factor receptor-bound protein 10; Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals fro [...]
2610318N02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000091026RIKEN cDNA 2610318N02 gene.
4933402J07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000091033RIKEN cDNA 4933402J07 gene.
Ogdh protein networkhttps://string-db.org/network/10090.ENSMUSP000000910412-oxoglutarate dehydrogenase, mitochondrial; 2-oxoglutarate dehydrogenase (E1) component of the 2- oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate. T [...]
Wdr83 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091048WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha [...]
Urgcp protein networkhttps://string-db.org/network/10090.ENSMUSP00000091053Up-regulator of cell proliferation; May be involved in cell cycle progression through the regulation of cyclin D1 expression.
Nefh protein networkhttps://string-db.org/network/10090.ENSMUSP00000091061Neurofilament heavy polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important [...]
Podnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091073Podocan-like protein 1.
Ccdc157 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091074Coiled-coil domain-containing protein 157.
Tbc1d9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091093TBC1 domain family member 9; May act as a GTPase-activating protein for Rab family protein(s).
Fcho1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091151F-BAR domain only protein 1; Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formati [...]
Ano8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091157Anoctamin-8; Does not exhibit calcium-activated chloride channel (CaCC) activity.
Ell protein networkhttps://string-db.org/network/10090.ENSMUSP00000091163RNA polymerase II elongation factor ELL; Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by [...]
Kxd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091165KxDL motif-containing protein 1; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BOR [...]
Csprs protein networkhttps://string-db.org/network/10090.ENSMUSP00000091219Component of Sp100-rs.
C130026I21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000091224RIKEN cDNA C130026I21 gene.
Sp110 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091226Sp110 nuclear body protein; May act as a transcription factor. Plays a role in the innate immunity against intracellular pathogens. Required for resistance to M.tuberculosis and L.monocytogenes. [...]
Fam149a protein networkhttps://string-db.org/network/10090.ENSMUSP00000091245Protein FAM149A; Belongs to the FAM149 family.
Zfp651 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091286Zinc finger protein 651.
Slc22a14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091289Solute carrier family 22 (Organic cation transporter), member 14.
Naa80 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091300N-alpha-acetyltransferase 80; N-alpha-acetyltransferase that specifically mediates the acetylation of the acidic amino terminus of processed forms of beta- and gamma-actin (ACTB and ACTG, respect [...]
Rassf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091301Ras association domain-containing protein 1; Potential tumor suppressor. Required for death receptor- dependent apoptosis. Mediates activation of Mediates activation of STK3/MST2 and STK4/MST1 du [...]
Cep63 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091306Centrosomal protein of 63 kDa; Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and [...]
Slc35g2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091308Solute carrier family 35 member G2.
Sox14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091310Transcription factor SOX-14; Acts as a negative regulator of transcription.
Cep70 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091312Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of [...]
Pls1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091317Plastin-1; Actin-bundling protein in the absence of calcium.
Plscr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091318Phospholipid scramblase 1; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry [...]
Cep162 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091319Centrosomal protein of 162 kDa; Required to promote assembly of the transition zone in primary cilia. Acts by specifically recognizing and binding the axonemal microtubule. Localizes to the dista [...]
Filip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091329Filamin-A-interacting protein 1; By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation o [...]
Cd109 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091330CD109 antigen; Modulates negatively TGFB1 signaling in keratinocytes.
Arhgef40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091331Rho guanine nucleotide exchange factor 40; May act as a guanine nucleotide exchange factor (GEF).
Myzap protein networkhttps://string-db.org/network/10090.ENSMUSP00000091342Myocardial zonula adherens protein; Plays a role in cellular signaling via Rho-related GTP- binding proteins and activation of transcription factor SRF. Targets TJP1 to cell junctions (By similar [...]
Lman1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000091352Protein ERGIC-53-like.
Trcg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091357Taste receptor cell protein 1.
Chrna5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091365Neuronal acetylcholine receptor subunit alpha-5; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-con [...]
Zbtb16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091374Zinc finger and BTB domain-containing 16.
Grin3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000091381Glutamate receptor ionotropic, NMDA3A.
Olfr895 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091387Olfactory receptor.
Olfr143 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091388Olfactory receptor 143; Odorant receptor.
Olfr894 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091389Olfactory receptor.
Olfr893 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091390Olfactory receptor.
Pate14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091391Secreted seminal-vesicle Ly-6 protein 1.
Arhgap42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091419Rho GTPase-activating protein 42; May influence blood pressure by functioning as a GTPase- activating protein for RHOA in vascular smooth muscle.
Tepsin protein networkhttps://string-db.org/network/10090.ENSMUSP00000091428AP-4 complex accessory subunit Tepsin; Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network.
Rnf213 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091429E3 ubiquitin-protein ligase RNF213; E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitina [...]
Tmem235 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091432Transmembrane protein 235; Belongs to the PMP-22/EMP/MP20 family.
Sept9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091435Septin-9; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin G [...]
Qrich2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091437Glutamine-rich protein 2; Has an essential role in the formation of sperm flagella and flagellar structure maintainance. It acts as a suppressor of ubiquitination and degradation of proteins invo [...]
Myo15b protein networkhttps://string-db.org/network/10090.ENSMUSP00000091439Myosin XVB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Tmem94 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091440Transmembrane protein 94.
Trim80 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091442Tripartite motif-containing 80.
Cdc27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091452Cell division cycle protein 27 homolog; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the [...]
Crhr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091455Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conf [...]
Fzd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091463Frizzled-2; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of [...]
Krtap31-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091467Keratin-associated protein 31-1.
Krtap9-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091468Keratin-associated protein 9-1.
Cdc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091469Cell division control protein 6 homolog; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiat [...]
Gsdma2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091470Gasdermin-A2; May promote pyroptosis. Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol ( [...]
Fbxo47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091471F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
Gpr179 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091474G protein-coupled receptor 179.
Cbx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091475Chromobox protein homolog 1; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) c [...]
Hoxb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091476Homeobox protein Hox-B3; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Mycbpap protein networkhttps://string-db.org/network/10090.ENSMUSP00000091477MYCBP-associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity).
Supt4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000091487Transcription elongation factor SPT4-A; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. [...]
Hsf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091488Heat shock factor protein 5; May act as a transcriptional factor.
Ccnd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091495G1/S-specific cyclin-D1; Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the [...]
Myo19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091502Unconventional myosin-XIX; Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane. Motor protein that moves towards the plus-end of actin filaments. Re [...]
Npnt protein networkhttps://string-db.org/network/10090.ENSMUSP00000091505Nephronectin; Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha- 8/beta-1 which is essential for kidney development. May als [...]
Arsj protein networkhttps://string-db.org/network/10090.ENSMUSP00000091511Arylsulfatase J.
Sez6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091532Seizure protein 6; May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and [...]
Abhd15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091541Protein ABHD15.
Abr protein networkhttps://string-db.org/network/10090.ENSMUSP00000091551Active breakpoint cluster region-related protein; Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activatin [...]
Fam57a protein networkhttps://string-db.org/network/10090.ENSMUSP00000091553TLC domain-containing protein 3A.
Plpp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091557Phospholipid phosphatase 4; Magnesium-independent phospholipid phosphatase with broad substrate specificity. Preferentially catalyzes the conversion of diacylglycerol pyrophosphate into phosphati [...]
Olfr382 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091575Olfactory receptor.
Tbx6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091579T-box transcription factor TBX6; T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulatin [...]
Tnrc6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000091595Trinucleotide repeat-containing gene 6A protein; Plays a role in RNA-mediated gene silencing by both micro- RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repress [...]
Tmem256 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091608Transmembrane protein 256.
Kdm6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000091620Lysine-specific demethylase 6B; Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethyla [...]
Tmem107 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091624Transmembrane protein 107; Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GL [...]
Tmem41b protein networkhttps://string-db.org/network/10090.ENSMUSP00000091641Transmembrane protein 41B; Required for normal motor neuron development. Required for autophagosome formation; Belongs to the TMEM41 family.
Hs3st3b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091647Heparan sulfate glucosamine 3-O-sulfotransferase 3B1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosam [...]
Cyp3a41a protein networkhttps://string-db.org/network/10090.ENSMUSP00000091659Cytochrome P450, family 3, subfamily a, polypeptide 41A.
Zscan25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091664Zinc finger and SCAN domain-containing 25.
Olfr558 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091674Olfactory receptor.
Rnf187 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091703E3 ubiquitin-protein ligase RNF187; E3 ubiquitin-protein ligase that acts as a coactivator of JUN-mediated gene activation in response to growth factor signaling via the MAP3K1 pathway, independe [...]
Tsku protein networkhttps://string-db.org/network/10090.ENSMUSP00000091713Tsukushin.
Meikin protein networkhttps://string-db.org/network/10090.ENSMUSP00000091745Meiosis-specific kinetochore protein; Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeri [...]
Mesd protein networkhttps://string-db.org/network/10090.ENSMUSP00000091768LRP chaperone MESD; Chaperone specifically assisting the folding of beta- propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt path [...]
Tlnrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091769Talin rod domain-containing protein 1; Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells.
Slc17a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091771Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and syna [...]
Ccl26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091779Chemokine (C-C motif) ligand 26.
Cldn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091799Claudin-3; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
Fam217b protein networkhttps://string-db.org/network/10090.ENSMUSP00000091805Family with sequence similarity 217, member B.
Catspere2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091828Cation channel sperm-associated protein subunit epsilon-like protein.
Zbtb18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091831Zinc finger and BTB domain-containing protein 18; Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Specifically binds the c [...]
Chchd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091835Coiled-coil-helix-coiled-coil-helix domain-containing protein 2; Transcription factor. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4 [...]
Snu13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091840NHP2-like protein 1, N-terminally processed; Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. [...]
Ctcfl protein networkhttps://string-db.org/network/10090.ENSMUSP00000091845Transcriptional repressor CTCFL; Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigen [...]
Wdr64 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091846WD repeat-containing protein 64.
Fcrl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091861Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic [...]
Rgma protein networkhttps://string-db.org/network/10090.ENSMUSP00000091870Repulsive guidance molecule A; Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube cl [...]
Ccdc62 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091878Coiled-coil domain-containing protein 62; Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocort [...]
Cdc25a protein networkhttps://string-db.org/network/10090.ENSMUSP00000091882M-phase inducer phosphatase 1; Tyrosine protein phosphatase which functions as a dosage- dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activit [...]
Lrrc43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091885Leucine-rich repeat-containing protein 43.
Nsmce3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091889Non-structural maintenance of chromosomes element 3 homolog; Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex [...]
Fcrlb protein networkhttps://string-db.org/network/10090.ENSMUSP00000091895Fc receptor-like B.
Peg12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091897Paternally-expressed 12.
Mkrn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091898Probable E3 ubiquitin-protein ligase makorin-3; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
Wfdc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091904WAP four-disulfide core domain 10.
Wfdc6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000091906WAP four-disulfide core domain protein 6B.
Tmem116 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091917Transmembrane protein 116.
Hsp90aa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091921Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle con [...]
Shc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091940SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and [...]
Tpd52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091943Tumor protein D52; Belongs to the TPD52 family.
Mrgprb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091945Mas-related G-protein coupled receptor member B3; Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sen [...]
Mrgprb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091946Mas-related G-protein coupled receptor member B1; Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sen [...]
Mrgprb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091952Mas-related G-protein coupled receptor member B4; Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sen [...]
Mrgprb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091953Mas-related G-protein coupled receptor member B5; Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sen [...]
Mrgprx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091954Mas-related G-protein coupled receptor member X1; Orphan receptor activated by neuropeptides terminating in Arg-Phe or Arg-Phe-amide. Mediates its action by association with G proteins that activ [...]
Iqcd protein networkhttps://string-db.org/network/10090.ENSMUSP00000091955Dynein regulatory complex protein 10; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the di [...]
Uevld protein networkhttps://string-db.org/network/10090.ENSMUSP00000091964Ubiquitin-conjugating enzyme E2 variant 3; Possible negative regulator of polyubiquitination. In the C-terminal section; belongs to the LDH/MDH superfamily.
Spaca4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000091991Sperm acrosome membrane-associated protein 4; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Belongs to the SPACA4/bou [...]
Ftl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092002Ferritin light chain 1; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after [...]
Hes3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092006Transcription factor HES-3; Transcriptional repressor of genes that require a bHLH protein for their transcription.
Tchp protein networkhttps://string-db.org/network/10090.ENSMUSP00000092009Trichoplein keratin filament-binding protein; Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. May act as a 'capping' or 'branching' protein [...]
Id1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092019DNA-binding protein inhibitor ID-1; Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming he [...]
Gpr157 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092020G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activat [...]
Wscd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092021WSC domain-containing protein 2.
Mn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092034Transcriptional activator MN1; Transcriptional activator which specifically regulates expression of TBX22 in the posterior region of the developing palate. Required during later stages of palate [...]
Entpd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092038Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family.
Selenom protein networkhttps://string-db.org/network/10090.ENSMUSP00000092041Selenoprotein M; May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation.
Insm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092048Insulinoma-associated protein 1; Sequence-specific DNA-binding transcriptional regulator that plays a key role in neurogenesis and neuroendocrine cell differentiation during embryonic and/or feta [...]
Gm12185 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092049Predicted gene 12185.
Rin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092053Ras and Rab interactor 2; Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF [...]
Fv1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092054Friend virus susceptibility protein 1; Retroviral restriction factor that prevents infection by gammaretroviruses. Acts by interacting with the capsid protein ca after entry of the virus into the [...]
Cfhr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092065Putative complement factor H-related protein B.
Vmn2r121 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092067Vomeronasal 2, receptor 121.
Vmn2r84 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092079Vomeronasal 2, receptor 84.
Aadacl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092087Arylacetamide deacetylase-like 4.
Gm13103 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092099Predicted gene, OTTMUSG00000010433.
Gm13119 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092103Predicted gene 13119.
Srarp protein networkhttps://string-db.org/network/10090.ENSMUSP00000092122Steroid receptor-associated and regulated protein; May regulate the transcriptional function of androgen and estrogen receptors.
Ren1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092135Renin-1; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an ele [...]
Golt1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000092136Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex; Belongs to the GOT1 family.
Arhgap24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092138Rho GTPase-activating protein 24; Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by con [...]
Nfasc protein networkhttps://string-db.org/network/10090.ENSMUSP00000092148Neurofascin; Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions; Belongs to the imm [...]
Sec31a protein networkhttps://string-db.org/network/10090.ENSMUSP00000092157Protein transport protein Sec31A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (By similarity). The coat [...]
Ffar3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092163Free fatty acid receptor 3; G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulatio [...]
BC061212 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092168cDNA sequence BC061212.
Galk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092186N-acetylgalactosamine kinase; Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations (By similarity).
Albfm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092198Albumin superfamily member 1.
Cdh19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092210Cadherin 19, type 2; Cadherins are calcium-dependent cell adhesion proteins.
Sars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092216Serine--tRNA ligase, mitochondrial; Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), w [...]
Map1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000092223Microtubule-associated protein 1A; Structural protein involved in the filamentous cross-bridging between microtubules and other skeletal elements; Belongs to the MAP1 family.
Csn1s1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092225Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate.
Plekhg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092228Pleckstrin homology domain-containing family G member 2; May be a transforming oncogene with exchange activity for CDC42. May be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42. Act [...]
Vps4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000092230Vacuolar protein sorting-associated protein 4B; Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes thei [...]
Ugt2b36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092233UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
Eid2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000092235EP300-interacting inhibitor of differentiation 2B.
Gtsf1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000092237Gametocyte-specific factor 1-like; Belongs to the UPF0224 (FAM112) family.
Dnajc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092242DnaJ homolog subfamily C member 8; Suppresses polyglutamine (polyQ) aggregation of ATXN3 in neuronal cells.
Gal3st2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092250Galactose-3-O-sulfotransferase 2.
Pla2g4d protein networkhttps://string-db.org/network/10090.ENSMUSP00000092252Cytosolic phospholipase A2 delta; Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Compared to its human ortholog, may have no preference [...]
Tmem200b protein networkhttps://string-db.org/network/10090.ENSMUSP00000092253Transmembrane protein 200B.
Wipf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092268WAS/WASL-interacting protein family member 1; Plays a role in the reorganization of the actin cytoskeleton. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participa [...]
B3gnt8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092277UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8; Beta-1,3-N-acetylglucosaminyltransferase that plays a role in the elongation of specific branch structures of multiantennary N- glyc [...]
Rmdn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092283Regulator of microtubule dynamics protein 3; Involved in cellular calcium homeostasis regulation (By similarity). May participate in differentiation and apoptosis of keratinocytes. Overexpression [...]
Rbm44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092286RNA-binding protein 44; Component of intercellular bridges during meiosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells. Not required for [...]
Zfp575 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092294Zinc finger protein 575; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Tmem35b protein networkhttps://string-db.org/network/10090.ENSMUSP00000092302Transmembrane protein 35B.
Grxcr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092305Glutaredoxin domain-containing cysteine-rich protein 1; May play a role in actin filament architecture in developing stereocilia of sensory cells; Belongs to the GRXCR1 family.
Ceacam20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092344Carcinoembryonic antigen-related cell adhesion molecule 20; Together with the tyrosine-protein kinase SYK, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a [...]
Relb protein networkhttps://string-db.org/network/10090.ENSMUSP00000092355Transcription factor RelB; NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, [...]
Inpp5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000092375Type II inositol 1,4,5-trisphosphate 5-phosphatase; Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5- trisphosphate (PtIns(1,4 [...]
Slc34a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092380Sodium-dependent phosphate transport protein 2B; May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intesti [...]
Gipr protein networkhttps://string-db.org/network/10090.ENSMUSP00000092384Gastric inhibitory polypeptide receptor; This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity).
Psg21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092387Pregnancy-specific glycoprotein 21.
Psg27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092388Pregnancy-specific glycoprotein 27.
Psg25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092389Pregnancy-specific glycoprotein 25.
Psg26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092392Pregnancy-specific glycoprotein 26.
Ceacam11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092393Carcinoembryonic antigen-related cell adhesion molecule 11.
Ccdc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092399Coiled-coil domain-containing protein 8 homolog; Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regul [...]
Pnmal2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092401PNMA-like 2.
Cited4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092408Cbp/p300-interacting transactivator 4; Acts as transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated by estrogen receptors. May function as an inhibitor [...]
Sae1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092409SUMO-activating enzyme subunit 1, N-terminally processed; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins f [...]
Dhx34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092410Probable ATP-dependent RNA helicase DHX34; Probable ATP-binding RNA helicase; Belongs to the DEAD box helicase family. DEAH subfamily.
Zmynd12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092414Zinc finger, MYND domain-containing 12.
Olfr1338 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092427Olfactory receptor 1338.
Zbtb49 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092429Zinc finger and BTB domain-containing protein 49; Transcription factor. Inhibits cell proliferation by activating either CDKN1A/p21 transcription or RB1 transcription.
Stk32b protein networkhttps://string-db.org/network/10090.ENSMUSP00000092432Serine/threonine-protein kinase 32B.
Cfap65 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092440Cilia- and flagella-associated protein 65; May play a role in sperm motility. Belongs to the CFAP65 family.
Vmn2r32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092462Vomeronasal 2, receptor 32.
Zfyve28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092464Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By [...]
Zfp787 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092468Zinc finger protein 787; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Cyp4a12b protein networkhttps://string-db.org/network/10090.ENSMUSP00000092487Cytochrome P450 4A12B; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids and their oxygenated derivatives (oxylipins). Mechanistically, uses molecular oxygen inserting one [...]
Il11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092492Interleukin-11; Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet prod [...]
Trabd2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000092494Metalloprotease TIKI2; Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following [...]
Dnaaf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092498Dynein assembly factor 3, axonemal; Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia (By simi [...]
Ccnyl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092499Cyclin Y-like 1.
Rps2 protein networkhttps://string-db.org/network/10090.ENSMUSP0000009250240S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
Cdc42ep5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092508Cdc42 effector protein 5; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pse [...]
Ldlrad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092521Low density lipoprotein receptor class A domain-containing 1.
Tmem237 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092522Transmembrane protein 237; Component of the transition zone in primary cilia. Required for ciliogenesis; Belongs to the TMEM237 family.
Usp24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092538Ubiquitin carboxyl-terminal hydrolase 24; Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Deubiquitinates DDB2, preventing its proteasomal degradation [...]
Gad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092539Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family.
Ccdc173 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092548Coiled-coil domain-containing protein 173.
Gm10471 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092553Predicted gene 10471.
Gm12689 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092562Predicted gene 12689.
Dnah7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000092571Dynein, axonemal, heavy chain 7A.
Ifna1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092580Interferon alpha-1; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Ifna4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092581Interferon alpha-4; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs t [...]
Gm13288 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092585Predicted gene 13277.
Gm13271 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092600Predicted gene 13271.
Klhl9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092602Kelch-like protein 9; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin [...]
Gm7347 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092613Predicted gene 7347.
Speer4d protein networkhttps://string-db.org/network/10090.ENSMUSP00000092615Spermatogenesis-associated glutamate (E)-rich protein 4D.
Tgfbrap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092624Transforming growth factor-beta receptor-associated protein 1; Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor comple [...]
Olfr356 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092631Olfactory receptor MOR134-1.
2310002L09Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000092633RIKEN cDNA 2310002L09 gene.
Aff3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092637AF4/FMR2 family member 3; Putative transcription activator that may function in lymphoid development and oncogenesis.
Zbtb43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092645Zinc finger and BTB domain-containing protein 43; May be involved in transcriptional regulation.
St6galnac6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092654Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; Alpha-2,6-sialyltransferase involved in the synthesis of alpha-series gangliosides. Has activity toward GD1a, GT1b and GM1b. Has no ac [...]
Mup15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092659Major urinary protein 15; Belongs to the calycin superfamily. Lipocalin family.
Mup8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092668Major urinary protein 5; Belongs to the calycin superfamily. Lipocalin family.
Inip protein networkhttps://string-db.org/network/10090.ENSMUSP00000092673SOSS complex subunit C; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates w [...]
Dnajc25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092680DnaJ homolog subfamily C member 25; Belongs to the DNAJC25 family.
Crispld1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092686Cysteine-rich secretory protein LCCL domain-containing 1.
Lrrc8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000092690Volume-regulated anion channel subunit LRRC8A; Essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell vo [...]
Actl7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000092692Actin-like protein 7A.
Actl7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000092693Actin-like protein 7B; Belongs to the actin family.
Olfr275 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092700Olfactory receptor.
Acnat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092702Acyl-coenzyme A amino acid N-acyltransferase 1; Acyltransferase which efficiently conjugates very long-chain and long-chain fatty acids to taurine. Shows no conjugation activity in the presence o [...]
Rapgef1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092703Rap guanine nucleotide exchange factor (GEF) 1.
Foxe1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092715Forkhead box protein E1; Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably throug [...]
Ccin protein networkhttps://string-db.org/network/10090.ENSMUSP00000092725Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation.
Hrct1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092727Histidine-rich carboxyl terminus protein 1.
Ccl21a protein networkhttps://string-db.org/network/10090.ENSMUSP00000092732C-C motif chemokine 21a; Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesang [...]
Mamdc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092735Apical endosomal glycoprotein; Probably involved in the sorting and selective transport of receptors and ligands across polarized epithelia.
Ndufb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092746NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved [...]
Gm136 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092748Uncharacterized protein C6orf163 homolog.
Spag6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092751Sperm-associated antigen 6.
Prdm13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092761PR domain zinc finger protein 13; May be involved in transcriptional regulation.
Dhtkd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092769Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It [...]
Phf11d protein networkhttps://string-db.org/network/10090.ENSMUSP00000092779PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression.
Ccdc7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000092780Coiled-coil domain-containing protein 7; May play a role in tumorigenesis.
Atp2c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092794Calcium-transporting ATPase type 2C member 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
Syce1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000092796Synaptonemal complex central element protein 1-like; May be involved in meiosis. Isoform 1 may be involved in meiosis during spermatogenesis while isoform 2 is probably related to a later stage o [...]
Srbd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092810S1 RNA-binding domain-containing protein 1.
Camkmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000092811Calmodulin-lysine N-methyltransferase; Catalyzes the trimethylation of 'Lys-116' in calmodulin.
Pdp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092821Pyruvate dehyrogenase phosphatase catalytic subunit 2.
Rasgrp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092828RAS, guanyl-releasing protein 3.
Capn13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092832Calpain-13; Probable non-lysosomal thiol-protease.
Ces1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000092836Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
Cnep1r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092839Nuclear envelope phosphatase-regulatory subunit 1; Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and [...]
Fbxw9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092845F-box and WD-40 domain protein 9.
Safb protein networkhttps://string-db.org/network/10090.ENSMUSP00000092849Scaffold attachment factor B1; Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR [...]
Samd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092853Atherin; May play a role in atherogenesis by immobilizing LDL in the atherial wall.
Gm10310 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092867Olfactory receptor.
Rpl7l1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000009288860S ribosomal protein L7-like 1; Belongs to the universal ribosomal protein uL30 family.
Yipf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092897Protein YIPF3, N-terminally processed; Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis (By similarity); Belongs to the YIP1 family.
Nxph4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092900Neurexophilin; May be signaling molecules that resemble neuropeptides.
Jund protein networkhttps://string-db.org/network/10090.ENSMUSP00000092901Transcription factor jun-D; Transcription factor binding AP-1 sites.
Slc26a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092904Solute carrier family 26 member 10; Chloride/bicarbonate exchanger; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
Nr2c2ap protein networkhttps://string-db.org/network/10090.ENSMUSP00000092907Nuclear receptor 2C2-associated protein; May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes.
Olfr761 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092917Olfactory receptor.
Trim75 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092932Tripartite motif-containing protein 75; Belongs to the TRIM/RBCC family.
Pawr protein networkhttps://string-db.org/network/10090.ENSMUSP00000092951PRKC apoptosis WT1 regulator protein; Pro-apoptotic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of [...]
1700029J07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000092961UPF0602 protein C4orf47 homolog.
Ccdc110 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092964Coiled-coil domain-containing protein 110.
Cyp4v3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092966Cytochrome P450 4V2; Omega-hydroxylase that oxidizes medium-chain saturated fatty acids and polyunsaturated omega-3 fatty acids, and which plays a role in fatty acid and steroid metabolism in the [...]
H2-Ob protein networkhttps://string-db.org/network/10090.ENSMUSP00000092985Histocompatibility 2, O region beta locus.
Mboat4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092988Ghrelin O-acyltransferase; Mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid; Belongs [...]
Ubxn8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092992UBX domain-containing protein 8; Involved in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins, possibly by tethering VCP to the endoplasmic reticulum membrane. M [...]
Aebp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000092993Zinc finger protein AEBP2; May interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3 (By similarity). DNA-binding transcriptio [...]
Tex24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093021Protein Tex24; Nuclear factor which might have a role in spermatogenesis.
Tmem263 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093030Transmembrane protein 263.
Tas2r140 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093040Taste receptor type 2 member 140; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestina [...]
Tas2r115 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093043Taste receptor type 2.
Tas2r121 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093044Taste receptor type 2 member 13; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal [...]
Klrh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093058Killer cell lectin-like receptor subfamily H, member 1.
Wdr20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093059WD repeat-containing protein 20.
Defa25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093075Alpha-defensin 25; May have microbicidal activities; Belongs to the alpha-defensin family.
Mtch1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093077Mitochondrial carrier homolog 1; Potential mitochondrial transporter. May play a role in apoptosis (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family.
Gm6040 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093080Predicted gene, EG574083.
Defb46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093087Beta-defensin 50.
Xkr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093089XK-related protein 5.
Syne3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093090Nesprin-3; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interac [...]
Akap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093091A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Belongs to the AKAP110 family.
Adamtsl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093097ADAMTS-like 5.
Odf3l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093117Outer dense fiber protein 3-like protein 2; Belongs to the ODF3 family.
Mucl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093120Mucin-like protein 3; May modulate NF-kappaB signaling and play a role in cell growth.
Lig4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093130DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-st [...]
Gm9507 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093145Predicted gene 9507.
Ccdc78 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093155Coiled-coil domain-containing protein 78; Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles [...]
Oog1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093165Oogenesin-1; May act as a Ras-mediated signaling protein in early embryogenesis; Belongs to the PRAME family.
Cog8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093173Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function.
Lrrc74a protein networkhttps://string-db.org/network/10090.ENSMUSP00000093183Leucine-rich repeat-containing 74A.
Fgf14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093185Fibroblast growth factor 14; Probably involved in nervous system development and function.
Susd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093197Sushi domain-containing protein 2; May be a cytokine receptor for C10ORF99. May be a tumor suppressor; together with C10ORF99 has a growth inhibitory effect on colon cancer cells which includes G [...]
Npw protein networkhttps://string-db.org/network/10090.ENSMUSP00000093200Neuropeptide W.
Syndig1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000093206Synapse differentiation-inducing gene protein 1-like; Belongs to the CD225/Dispanin family.
Scel protein networkhttps://string-db.org/network/10090.ENSMUSP00000093233Sciellin; May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sc [...]
Cldn9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093236Claudin-9; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Mypn protein networkhttps://string-db.org/network/10090.ENSMUSP00000093240Myopalladin; Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines.
Adgrv1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093245Adhesion G-protein coupled receptor V1; G-protein coupled receptor which has an essential role in the development of hearing and vision. Couples to G-alpha(i)-proteins, GNAI1/2/3, G-alpha(q)-prot [...]
Zscan10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093255Zinc finger and SCAN domain-containing protein 10; Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Can both activate and /or repress expression o [...]
Zfp213 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093266Zinc finger protein 213.
Fpr-rs6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093296Formyl peptide receptor-related sequence 6; May have an olfactory function associated with the identification of pathogens or of pathogenic states.
Fpr-rs7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093297Formyl peptide receptor-related sequence 7; May have an olfactory function associated with the identification of pathogens or of pathogenic states.
Fpr-rs4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093311Formyl peptide receptor-related sequence 4; May have an olfactory function associated with the identification of pathogens or of pathogenic states.
Lmod3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093315Leiomodin-3; Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization (By similarity). Belongs to the tropomodulin family.
Fpr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093316Formyl peptide receptor-related sequence 1; Low affinity receptor for N-formyl-methionyl peptides. Receptor for lipoxin A4. May have an olfactory function associated with the identification of pa [...]
Tmf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093325TATA element modulatory factor; Potential coactivator of the androgen receptor. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and t [...]
Pkib protein networkhttps://string-db.org/network/10090.ENSMUSP00000093329cAMP-dependent protein kinase inhibitor beta; Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme aft [...]
Slc5a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093379High affinity choline transporter 1; Transmembrane transporter that imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acet [...]
Bves protein networkhttps://string-db.org/network/10090.ENSMUSP00000093382Blood vessel epicardial substance; Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) p [...]
Pdss2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093393Decaprenyl-diphosphate synthase subunit 2; Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10. Belongs to the FPP/GGPP synthase family.
Akap6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093406A kinase (PRKA) anchor protein 6.
Tia1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093425Nucleolysin TIA-1; Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses n [...]
Usp51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093427Ubiquitin carboxyl-terminal hydrolase 51; Deubiquitinates histone H2A at 'Lys-13' and 'Lys-15' and regulates DNA damage response. USP51 is recruited to chromatin after DNA damage and regulates th [...]
Nat8f4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093430N-acetyltransferase 8 (GCN5-related) family member 4.
Nat8f3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093431N-acetyltransferase family 8 member 3.
Trappc3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000093432Trafficking protein particle complex subunit 3-like protein; May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Egr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093433Early growth response protein 4; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCGGGGGCG-3' (GSG). Activates the transcription of target genes whose products are required [...]
Lsmem1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093434Leucine-rich single-pass membrane protein 1.
Trdn protein networkhttps://string-db.org/network/10090.ENSMUSP00000093436Triadin; Contributes to the regulation of lumenal Ca2+ release via the sarcoplasmic reticulum calcium release channels RYR1 and RYR2, a key step in triggering skeletal and heart muscle contractio [...]
Etv1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093442ETS translocation variant 1; Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
Cdhr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093449Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may th [...]
Moxd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093460DBH-like monooxygenase protein 1; Belongs to the copper type II ascorbate-dependent monooxygenase family.
Pole4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093462DNA polymerase epsilon subunit 4; Accessory component of the DNA polymerase epsilon complex (By similarity). Participates in DNA repair and in chromosomal DNA replication (By similarity).
Rnf17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093469RING finger protein 17; Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad-MAX heterodimers. Can recruit Mad transcriptional rep [...]
Spin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093473Spindlin-1; Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activ [...]
Mcpt9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093476Mast cell protease 9.
Map3k5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093485Mitogen-activated protein kinase kinase kinase 5; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascad [...]
Ect2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000093497Epithelial cell-transforming sequence 2 oncogene-like.
Prdm15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093533PR domain zinc finger protein 15; Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell [...]
Grid2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093536Glutamate receptor ionotropic, delta-2; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu [...]
Slc7a15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093548Solute carrier family 7 (cationic amino acid transporter, y+ system), member 15.
Armt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093581Damage-control phosphatase ARMT1; Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate (By similarity). [...]
Dusp22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093603Dual specificity protein phosphatase 22; Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK).
Vmn2r12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093612Vomeronasal 2, receptor 12.
Prl7a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093614Prolactin-7A1; Belongs to the somatotropin/prolactin family.
Pnp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093615Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formati [...]
Ccnb1ip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093622E3 ubiquitin-protein ligase CCNB1IP1; Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS [...]
Krtap26-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093626Keratin-associated protein 26-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Habp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093641Hyaluronan-binding protein 2 27 kDa light chain alternate form; Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen an [...]
Vti1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000093644Vesicle transport through interaction with t-SNAREs homolog 1A; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are [...]
Ptgdr protein networkhttps://string-db.org/network/10090.ENSMUSP00000093653Prostaglandin D2 receptor; Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of i [...]
Gm8165 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093679Predicted gene 8165.
Itprip protein networkhttps://string-db.org/network/10090.ENSMUSP00000093697Inositol 1,4,5-trisphosphate receptor-interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release. Belongs to the ITPRIP family.
Gm10334 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093698Predicted gene 10334; Belongs to the peptidase S1 family.
Sh2d4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000093699SH2 domain-containing protein 4B.
Prss3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093702Protease, serine 3; Belongs to the peptidase S1 family.
Psd protein networkhttps://string-db.org/network/10090.ENSMUSP00000093729PH and SEC7 domain-containing protein 1; Guanine nucleotide exchange factor for ARF6 (By similarity). Isoform 2 and isoform 3 induce cytoskeletal remodeling, but lead to distinct morphological ch [...]
Klrg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093732Killer cell lectin-like receptor subfamily G member 2.
3425401B19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000093741Cardiac-enriched FHL2-interacting protein; Plays an important role in cardiomyocyte hypertrophy via activation of the calcineurin/NFAT signaling pathway.
Svopl protein networkhttps://string-db.org/network/10090.ENSMUSP00000093743Putative transporter SVOPL; Belongs to the major facilitator superfamily.
Dppa4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093749Developmental pluripotency-associated protein 4; May be involved in the maintenance of active epigenetic status of target genes. May inhibit differentiation of embryonic stem (ES) cells into a pr [...]
Slf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093758SMC5-SMC6 complex localization factor protein 2; Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance. Th [...]
Tagln3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093762Transgelin-3; Belongs to the calponin family.
Tigit protein networkhttps://string-db.org/network/10090.ENSMUSP00000093770T-cell immunoreceptor with Ig and ITIM domains; Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses [...]
Cpa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093771Carboxypeptidase A2.
Tasor2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093774Protein TASOR 2; Belongs to the TASOR family.
Ccdc136 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093789Coiled-coil domain-containing protein 136; May play a role in acrosome formation in spermatogenesis and in fertilization.
Cstdc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093794Cystatin domain-containing 5.
Csta1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093795Cystatin-A; This is an intracellular thiol proteinase inhibitor. Belongs to the cystatin family.
Muc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093813Mucin-4.
Ifit1bl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093816Interferon-induced protein with tetratricopeptide repeats 1B-like 2.
Pigx protein networkhttps://string-db.org/network/10090.ENSMUSP00000093819Phosphatidylinositol-glycan biosynthesis class X protein; Essential component of glycosylphosphatidylinositol- mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor [...]
Cstf2t protein networkhttps://string-db.org/network/10090.ENSMUSP00000093831Cleavage stimulation factor subunit 2 tau variant; May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre- mRNAs.
Gm5458 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093833Predicted gene 5458.
Il1rap protein networkhttps://string-db.org/network/10090.ENSMUSP00000093843Interleukin-1 receptor accessory protein; Coreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the [...]
Fam189a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093878Protein FAM189A2; Belongs to the FAM189 family.
Gm10408 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093882Predicted gene 10408.
Cemip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093908Cell surface hyaluronidase; Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate- size hyaluronan of approximately 5 k [...]
Vwa5b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093911Von Willebrand factor A domain-containing protein 5B2.
Tmprss12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093914Transmembrane protease serine 12.
Olfr1472 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093915Olfactory receptor.
Adcy6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093939Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors. Functions in signaling cascades downstream of beta- adrenergic receptor [...]
Eef1g protein networkhttps://string-db.org/network/10090.ENSMUSP00000093955Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.
Tut1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093958Speckle targeted PIP5K1A-regulated poly(A) polymerase; Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates [...]
Mta2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093959Metastasis-associated protein MTA2; May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.
Eml3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093960Echinoderm microtubule-associated protein-like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; Belongs to the WD repeat EMAP fam [...]
Rom1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093961Rod outer segment membrane protein 1; Plays a role in rod outer segment (ROS) morphogenesis. May play a role with PRPH2 in the maintenance of the structure of ROS curved disks (By similarity). Pl [...]
B3gat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093962Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3; Glycosaminoglycans biosynthesis. Involved in forming the linkage tetrasaccharide present in heparan sulfate and chondroitin su [...]
Ganab protein networkhttps://string-db.org/network/10090.ENSMUSP00000093965Neutral alpha-glucosidase AB; Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precur [...]
Ints5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093968Integrator complex subunit 5; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The [...]
Arid2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093969AT-rich interactive domain-containing protein 2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required fo [...]
1810009A15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000093970Uncharacterized protein C11orf98 homolog.
Uqcc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093972Ubiquinol-cytochrome-c reductase complex assembly factor 3; Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b- [...]
Lrrn4cl protein networkhttps://string-db.org/network/10090.ENSMUSP00000093976LRRN4 C-terminal-like protein.
Gng3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093978Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling sy [...]
Polr2g protein networkhttps://string-db.org/network/10090.ENSMUSP00000093980DNA-directed RNA polymerase II subunit RPB7; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
Foxr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093984Forkhead box protein R2.
Slc22a30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093988Solute carrier family 22, member 30.
Slc22a27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093991Solute carrier family 22 member 27; [Isoform 1]: Does not appear to have transporter activity. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) fa [...]
Cpped1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000093992Serine/threonine-protein phosphatase CPPED1; Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. M [...]
Htr2c protein networkhttps://string-db.org/network/10090.ENSMUSP000000940215-hydroxytryptamine receptor 2C; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkalo [...]
Tbc1d8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000094036TBC1 domain family member 8B; Involved in vesicular recycling, probably as a RAB11B GTPase- activating protein.
Tex13a protein networkhttps://string-db.org/network/10090.ENSMUSP00000094038Testis-expressed 13A.
Ap5b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094042AP-5 complex subunit beta-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport.
Armcx5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094045Armadillo repeat-containing X-linked protein 5.
Gm382 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094056Predicted gene 382.
Gpr152 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094062Probable G-protein coupled receptor 152; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Kcnj4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094075Inward rectifier potassium channel 4; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dep [...]
Maff protein networkhttps://string-db.org/network/10090.ENSMUSP00000094076Transcription factor MafF; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve [...]
Magee1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094078Melanoma-associated antigen E1; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of [...]
Csf2rb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094083Interleukin-3 receptor class 2 subunit beta; In mouse, there are two classes of high-affinity IL3 receptors. One contains this IL3-specific beta subunit and the other contains the beta subunit al [...]
Ncf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094084Neutrophil cytosol factor 4; Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, [...]
Apol7e protein networkhttps://string-db.org/network/10090.ENSMUSP00000094085Apolipoprotein L 7e.
Awat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094088Acyl-CoA wax alcohol acyltransferase 1; Acyltransferase that catalyzes the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters (By similarity). Shows a stro [...]
Tmem28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094090Transmembrane protein FAM155B.
Scrt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094093Transcriptional repressor scratch 1; Transcriptional repressor that binds E-box motif CAGGTG (By similarity). Appears to function downstream of proneural bHLH proteins in promoting neural differe [...]
Spin4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094095Spindlin-4; Exhibits H3K4me3-binding activity. Belongs to the SPIN/STSY family.
Mroh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094115Maestro heat-like repeat family member 1.
Gml2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094130Glycosylphosphatidylinositol-anchored molecule-like 2.
Gml protein networkhttps://string-db.org/network/10090.ENSMUSP00000094131Glycosylphosphatidylinositol-anchored molecule-like.
A1bg protein networkhttps://string-db.org/network/10090.ENSMUSP00000094151Alpha-1B-glycoprotein.
Gm14698 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094153Serine/threonine/tyrosine-interacting protein; Catalytically inactive phosphatase. Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2) (By similarity). Modulates cell-fate decisions and cell mig [...]
4933412E24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000094154Uncharacterized protein CXorf49 homolog.
Zhx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094164Zinc fingers and homeoboxes protein 2; Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA (By similarity). May play a role in retinal devel [...]
Adgrg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094165Adhesion G-protein coupled receptor G4; Orphan receptor.
Deptor protein networkhttps://string-db.org/network/10090.ENSMUSP00000094167DEP domain-containing mTOR-interacting protein; Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes (By similarity).
Morc2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000094176ATPase MORC2A; Essential for epigenetic silencing by the HUSH complex. Recruited by HUSH to target site in heterochromatin, the ATPase activity and homodimerization are critical for HUSH-mediated [...]
Rhox12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094191Reproductive homeobox on X chromosome 12.
Btg1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000094192BTG anti-proliferation factor 1C.
Rhox7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000094193Reproductive homeobox 7A.
Rhox3h protein networkhttps://string-db.org/network/10090.ENSMUSP00000094196Reproductive homeobox 3H.
Rhox4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000094197Reproductive homeobox 4B.
Rhox3a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094198Reproductive homeobox on X chromosome 3.
Gm5169 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094211Predicted gene, 382277.
Skp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094225S-phase kinase-associated protein 2; Substrate recognition component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent prot [...]
Egflam protein networkhttps://string-db.org/network/10090.ENSMUSP00000094238Pikachurin; Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Necessary for proper bipolar dendritic tip apposition to the phot [...]
Med14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094239Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Fthl17e protein networkhttps://string-db.org/network/10090.ENSMUSP00000094254Ferritin heavy polypeptide-like 17.
Loxhd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094294Lipoxygenase homology domain-containing protein 1; Required for normal function of hair cells in the inner ear.
Dnajc30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094318DnaJ homolog subfamily C member 30, mitochondrial; Mitochondrial protein enriched in neurons that acts as a regulator of mitochondrial respiration. Associates with the ATP synthase complex and fa [...]
Gm94 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094321Uncharacterized protein C5orf46 homolog.
Map3k2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094326Mitogen-activated protein kinase kinase kinase 2; Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K [...]
Mroh9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094365Maestro heat-like repeat family member 9.
Nutm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094390NUT family member 2; Belongs to the NUT family.
Rnf121 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094396RING finger protein 121; Belongs to the RNF121 family.
Adam25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094420Disintegrin and metalloproteinase domain-containing protein 25; Sperm surface membrane protein that may be involved in spermatogenesis and fertilization.
Smok2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000094432Sperm motility kinase 2A; May play a role in sperm motility, especially in the regulation of flagellar function.
Il22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094449Interleukin-22; Cytokine that contributes to the inflammatory response in vivo; Belongs to the IL-10 family.
Ttc9c protein networkhttps://string-db.org/network/10090.ENSMUSP00000094513Tetratricopeptide repeat protein 9C; Belongs to the TTC9 family.
Hnrnpul2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094515Heterogeneous nuclear ribonucleoprotein U-like protein 2.
Eml4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094528Echinoderm microtubule-associated protein-like 4; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
Vmn2r122 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094553Vomeronasal 2, receptor, 122.
Ang6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094632Angiogenin, ribonuclease A family, member 6; Belongs to the pancreatic ribonuclease family.
Reg3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000094667Regenerating islet-derived protein 3-beta 16.5 kDa form; Bactericidal C-type lectin which acts against several intestinal Gram-positive and Gram-negative bacteria. Lacks antibacterial activity ag [...]
Slx protein networkhttps://string-db.org/network/10090.ENSMUSP00000094676Sycp3-like X-linked.
Gm10354 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094716Predicted gene 10354.
Sept5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094750Septin-5; Filament-forming cytoskeletal GTPase (By similarity). Involved in cytokinesis (Potential). May play a role in platelet secretion; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-l [...]
Tuba1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000094778Detyrosinated tubulin alpha-1A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site [...]
Fthl17f protein networkhttps://string-db.org/network/10090.ENSMUSP00000094793Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Taf1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000094808TATA box-binding protein-associated factor RNA polymerase I subunit A; Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation compl [...]
Gm5592 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094809Uncharacterized protein C2orf78 homolog.
C2cd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094845C2 calcium-dependent domain-containing 6.
Gpx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094863Phospholipid hydroperoxide glutathione peroxidase; Essential antioxidant peroxidase that directly reduces phospholipid hydroperoxide even if they are incorporated in membranes and lipoproteins. C [...]
Prkce protein networkhttps://string-db.org/network/10090.ENSMUSP00000094874Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cell [...]
Heatr5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000094882HEAT repeat-containing protein 5B.
Togaram2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094886TOG array regulator of axonemal microtubules protein 2.
L3mbtl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094892Lethal(3)malignant brain tumor-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromat [...]
Lrrc30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094893Leucine-rich repeat-containing protein 30.
Arrdc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094906Arrestin domain-containing protein 5; Belongs to the arrestin family.
Foxp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094916Forkhead box protein P4; Transcriptional repressor that represses lung-specific expression.
Esp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094930Exocrine gland-secreting peptide 6.
Olfr120 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094931Olfactory receptor.
Olfr98 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094936Olfactory receptor.
Gm6034 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094943Predicted gene 6034.
Lst1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094949Leukocyte-specific transcript 1 protein; Possible role in modulating immune responses. Has an inhibitory effect on lymphocyte proliferation. Induces morphological changes including production of [...]
Nelfe protein networkhttps://string-db.org/network/10090.ENSMUSP00000094956Negative elongation factor E; Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (By similarity). The NELF complex, [...]
Pknox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094966Homeobox protein PKNOX1; Activates transcription in the presence of PBX1A and HOXA1. Belongs to the TALE/MEIS homeobox family.
Pigq protein networkhttps://string-db.org/network/10090.ENSMUSP00000094981Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first [...]
Tsc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094986Tuberin; In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By [...]
Tbc1d24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094989TBC1 domain family member 24; May act as a GTPase-activating protein for Rab family protein(s). Involved in neuronal projections development, probably through a negative modulation of ARF6 functi [...]
Vmn2r112 protein networkhttps://string-db.org/network/10090.ENSMUSP00000094994Vomeronasal 2, receptor 112.
Ermard protein networkhttps://string-db.org/network/10090.ENSMUSP00000095005ER membrane-associated RNA degradation.
Gm3435 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095007Predicted gene 3435.
Gm3417 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095011Tctex1 domain-containing protein 3; May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility.
Tcp10c protein networkhttps://string-db.org/network/10090.ENSMUSP00000095015T-complex protein 10c.
Ccr6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095029C-C chemokine receptor type 6; Receptor for the C-C type chemokine CCL20. Binds to CCL20 and subsequently transduces a signal by increasing the intracellular calcium ion levels. Although CCL20 is [...]
Fgfr1op protein networkhttps://string-db.org/network/10090.ENSMUSP00000095030FGFR1 oncogene partner; Required for anchoring microtubules to the centrosomes. Required for ciliation; Belongs to the FGFR1OP family.
Gm1604b protein networkhttps://string-db.org/network/10090.ENSMUSP00000095033Gene model 1604B, (NCBI).
Rsph3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000095034Radial spoke head protein 3 homolog A; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK [...]
Fndc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095036Fibronectin type III domain-containing 1.
Sytl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095041Synaptotagmin-like protein 3; May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions.
Serac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095043Protein SERAC1; Plays an important role in the phosphatidylglycerol remodeling that is essential for both mitochondrial function and intracellular cholesterol trafficking. May catalyze the remode [...]
Ptpn14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095051Tyrosine-protein phosphatase non-receptor type 14; Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migrat [...]
Ccdc185 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095053Coiled-coil domain-containing 185.
Ifi213 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095070Interferon-activated gene 213.
Gm10521 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095074Predicted gene 10521.
9930111J21Rik1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095102RIKEN cDNA 9930111J21 gene 1.
Dok6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095103Docking protein 6; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret- [...]
Hdhd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095129Haloacid dehalogenase-like hydrolase domain-containing protein 2; Belongs to the HAD-like hydrolase superfamily.
Tor1aip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095134Torsin-1A-interacting protein 1; Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-typ [...]
Mbd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095137Methyl-CpG-binding domain protein 1; Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is aboli [...]
Cep76 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095149Centrosomal protein of 76 kDa; Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplic [...]
Spink13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095165Serine protease inhibitor Kazal-type 13; May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from [...]
Csrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095169Cysteine and glycine-rich protein 1; Could play a role in neuronal development.
Cd74 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095171H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after [...]
Synpo protein networkhttps://string-db.org/network/10090.ENSMUSP00000095174Synaptopodin; Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the forma [...]
Spink11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095194Serine protease inhibitor Kazal-type 11; Probable serine protease inhibitor.
Srgap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095195SLIT-ROBO Rho GTPase-activating protein 2; RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Play [...]
Lars protein networkhttps://string-db.org/network/10090.ENSMUSP00000095197Leucine--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and [...]
Grxcr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095198Glutaredoxin domain-containing cysteine-rich protein 2; Could play a role in maintaining cochlear stereocilia bundles that are involved in sound detection; Belongs to the GRXCR1 family.
Arhgap26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095200Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42.
1700066B19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000095222Small integral membrane protein 33.
Ecscr protein networkhttps://string-db.org/network/10090.ENSMUSP00000095223Endothelial cell-specific chemotaxis regulator; Regulates endothelial chemotaxis and tube formation (By similarity). Has a role in angiogenesis and apoptosis via modulation of the actin cytoskele [...]
Pam protein networkhttps://string-db.org/network/10090.ENSMUSP00000095228Peptidyl-alpha-hydroxyglycine alpha-amidating lyase; Bifunctional enzyme that catalyzes the post-translational modification of inactive peptidylglycine precursors to the corresponding bioactive a [...]
Gal3st2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000095234Galactose-3-O-sulfotransferase 2C.
Cops9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095247COP9 signalosome complex subunit 9; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator [...]
AW554918 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095248Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes.
Hdac4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095249Histone deacetylase 4; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic rep [...]
2700062C07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000095251UPF0711 protein C18orf21 homolog; Belongs to the UPF0711 family.
Ramp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095253Receptor activity-modifying protein 1; Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP [...]
Lrrfip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095254Leucine-rich repeat flightless-interacting protein 1; Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF [...]
Asxl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095260Putative Polycomb group protein ASXL3; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive s [...]
Ugt1a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095263UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
Fbxo36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095276F-box only protein 36; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Retreg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095300Reticulophagy regulator 2.
Catip protein networkhttps://string-db.org/network/10090.ENSMUSP00000095303Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization; Belongs to the CATIP family.
Pikfyve protein networkhttps://string-db.org/network/10090.ENSMUSP000000953141-phosphatidylinositol 3-phosphate 5-kinase; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the pho [...]
Idh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095316Isocitrate dehydrogenase [NADP] cytoplasmic; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Plekhm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095320Pleckstrin homology domain-containing family M member 3; Involved in skeletal muscle differentiation. May act as a scaffold protein for AKT1 during muscle differentiation.
Mrpl43 protein networkhttps://string-db.org/network/10090.ENSMUSP0000009532239S ribosomal protein L43, mitochondrial.
Fam126b protein networkhttps://string-db.org/network/10090.ENSMUSP00000095331Protein FAM126B; Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane.
Pusl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095344tRNA pseudouridine synthase-like 1; Belongs to the tRNA pseudouridine synthase TruA family.
Pgap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095346GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic re [...]
Tmem88b protein networkhttps://string-db.org/network/10090.ENSMUSP00000095349Transmembrane protein 88B.
Il1rl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095379Interleukin-1 receptor-like 1; Receptor for interleukin-33 (IL-33); signaling requires association of the coreceptor IL1RAP. Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by p [...]
Klhl21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095380Kelch-like protein 21; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiq [...]
Arid5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000095385AT-rich interactive domain-containing protein 5A; DNA-binding protein that may regulate transcription and act as a repressor by binding to AT-rich stretches in the promoter region of target genes [...]
4931408C20Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000095410RIKEN cDNA 4931408C20 gene.
Rims1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095420Regulating synaptic membrane exocytosis protein 1; Rab effector involved in exocytosis. May act as scaffold protein that regulates neurotransmitter release at the active zone. Essential for maint [...]
Cplane2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095422Ciliogenesis and planar polarity effector 2; Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle [...]
Defb41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095426Beta-defensin 41; Has bactericidal activity; Belongs to the beta-defensin family.
Defb18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095427Beta-defensin 18; Has antibacterial activity; Belongs to the beta-defensin family.
Ubr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095433E3 ubiquitin-protein ligase UBR4; E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are desta [...]
Otud3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095441OTU domain-containing protein 3; Deubiquitinating enzyme that hydrolyzes 'Lys-6'- and 'Lys- 11'-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains (By sim [...]
Cnr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095454Cannabinoid receptor 2; Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, noci [...]
Zpld2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095461Zona pellucida-like domain-containing 2.
Zscan20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095487Zinc finger and SCAN domain-containing protein 20; May be involved in transcriptional regulation.
Ago1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095498Protein argonaute-1; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs whi [...]
Sh3d21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095501SH3 domain-containing protein 21.
Macf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095507Microtubule-actin cross-linking factor 1; [Isoform 2]: F-actin-binding protein which plays a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an im [...]
Svbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000095518Small vasohibin-binding protein; Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin. Also requir [...]
Kncn protein networkhttps://string-db.org/network/10090.ENSMUSP00000095531Kinocilin; May play a role in stabilizing dense microtubular networks or in vesicular trafficking.
Agbl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095533Cytosolic carboxypeptidase 6; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational [...]
Cdkn2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000095534Cyclin-dependent kinase 4 inhibitor C; Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB; [...]
Krtap5-5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095555Keratin-associated protein 5-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated protein (KRTAP), which a [...]
Mier1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095558Mesoderm induction early response protein 1; Transcriptional repressor regulating the expression of a number of genes including SP1 target genes. Probably functions through recruitment of HDAC1 a [...]
Sigirr protein networkhttps://string-db.org/network/10090.ENSMUSP00000095571Single Ig IL-1-related receptor; Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor- proximal signaling components to the [...]
Efcab7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095572EF-hand calcium-binding domain-containing protein 7; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Required for the localization of the EVC2:EVC subcompl [...]
Alg6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095574Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from d [...]
Spef1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000095584Sperm flagellar 1-like.
Cdkn2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000095595Cyclin-dependent kinase 4 inhibitor B; Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest (By similarity); Belongs to the CDKN2 cycl [...]
Nps protein networkhttps://string-db.org/network/10090.ENSMUSP00000095597Neuropeptide S; May play an important anorexigenic role. Modulates arousal and anxiety as well as increases locomotor activity. Binds to its receptor NPSR1 with nanomolar affinity to increase int [...]
Focad protein networkhttps://string-db.org/network/10090.ENSMUSP00000095602Focadhesin; Potential tumor suppressor in gliomas.
Fam53b protein networkhttps://string-db.org/network/10090.ENSMUSP00000095608Protein FAM53B; Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) nuclear localization. Belongs to the FAM53 family.
Gm49368 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095625Predicted gene, 49368; Belongs to the integrin alpha chain family.
Mup18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095648Major urinary protein 11; Major urinary proteins (Mups) bind pheromones, and thus stabilize them to allow slow release into the air from urine marks. May protect pheromones from oxidation. May al [...]
Mup11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095654Major urinary protein 11.
Mup10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095655Major urinary protein 2; Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females.
Tufm protein networkhttps://string-db.org/network/10090.ENSMUSP00000095656Elongation factor Tu, mitochondrial; Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy [...]
Aqp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095664Aquaporin-8; Forms a water-specific channel; mercury-sensitive. Also permeable to urea but not to glycerol; Belongs to the MIP/aquaporin (TC 1.A.8) family.
Musk protein networkhttps://string-db.org/network/10090.ENSMUSP00000095665Muscle, skeletal receptor tyrosine-protein kinase; Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse betwee [...]
Palb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095675Partner and localizer of BRCA2; Plays a critical role in homologous recombination repair (HRR) through its ability to recruit BRCA2 and RAD51 to DNA breaks. Strongly stimulates the DNA strand-inv [...]
Zfp462 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095677Zinc finger protein 462; Zinc finger nuclear factor involved in transcription by regulating chromatin structure and organization. Involved in the pluripotency and differentiation of embryonic ste [...]
Acsm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095690Acyl-coenzyme A synthetase ACSM2, mitochondrial; Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (By similarity). Capable of activat [...]
Coq7 protein networkhttps://string-db.org/network/10090.ENSMUSP000000956955-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural rol [...]
Rnf38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095702E3 ubiquitin-protein ligase RNF38; Acts as an E3 ubiquitin-protein ligase able to ubiquitinate p53/TP53 which promotes its relocalization to discrete foci associated with PML nuclear bodies. Exhi [...]
Rusc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095710Iporin.
Pigo protein networkhttps://string-db.org/network/10090.ENSMUSP00000095713GPI ethanolamine phosphate transferase 3; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannos [...]
Gm13305 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095725Interleukin-11 receptor subunit alpha-2; Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL1 [...]
Gm13304 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095727C-C motif chemokine 21b; Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesang [...]
Gm21541 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095732Predicted gene, 21541.
Il11ra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095736Interleukin-11 receptor subunit alpha-1; Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL1 [...]
Ppfibp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095738Liprin-beta-2; May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A (By similarity).
Rbmxl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095739RNA-binding motif protein, X-linked-like 2.
Olfr713 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095743Olfactory receptor.
Nfx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095747Transcriptional repressor NF-X1; Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response b [...]
Rrp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095752Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy [...]
Olfr688 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095758Olfactory receptor 688; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr656 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095774Olfactory receptor.
Olfr654 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095775Olfactory receptor MOR38-2.
Trim5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095781Tripartite motif-containing 5.
Trim6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095782Tripartite motif-containing protein 6; E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells [...]
Pm20d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095783Peptidase M20 domain-containing protein 2.
Olfr635 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095788Olfactory receptor.
Rragd protein networkhttps://string-db.org/network/10090.ENSMUSP00000095792Ras-related GTP-binding protein D; Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its sub [...]
Hbb-bt protein networkhttps://string-db.org/network/10090.ENSMUSP00000095794Hemoglobin, beta adult t chain.
Olfr628 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095795Olfactory receptor.
Olfr593 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095807Olfactory receptor MOR24-2.
Olfr584 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095811Olfactory receptor.
Olfr583 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095812Olfactory receptor.
Olfr582 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095813Olfactory receptor.
Olfr574 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095815Olfactory receptor.
Olfr568 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095818Olfactory receptor.
Olfr555 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095823Olfactory receptor.
Olfr547 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095831Olfactory receptor.
Ggh protein networkhttps://string-db.org/network/10090.ENSMUSP00000095843Gamma-glutamyl hydrolase; Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-g [...]
Ttpa protein networkhttps://string-db.org/network/10090.ENSMUSP00000095845Alpha-tocopherol transfer protein; Binds alpha-tocopherol, enhances its transfer between separate membranes, and stimulates its release from liver cells. Binds both phosphatidylinol 3,4-bisphosph [...]
Arrb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095866Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous d [...]
Klhl40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095873Kelch-like protein 40; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The BCR(KLHL40) complex acts by [...]
B3gnt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095879Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase; Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important [...]
Omp protein networkhttps://string-db.org/network/10090.ENSMUSP00000095882Olfactory marker protein; May act as a modulator of the olfactory signal-transduction cascade; Belongs to the olfactory marker protein family.
Alg8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095901Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers [...]
Exoc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095915Exocyst complex component 8; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Mc1r protein networkhttps://string-db.org/network/10090.ENSMUSP00000095929Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to th [...]
Ankrd11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095939Ankyrin repeat domain-containing protein 11; Chromatin regulator which modulates histone acetylation and gene expression in neural precursor cells. May recruit histone deacetylases (HDACs) to the [...]
Prss44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095948Serine protease 44; Belongs to the peptidase S1 family.
Man2a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095949Alpha-mannosidase 2x; Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N- glycans; the final hydrolytic step in the N [...]
Scap protein networkhttps://string-db.org/network/10090.ENSMUSP00000095953Sterol regulatory element-binding protein cleavage-activating protein; Escort protein required for cholesterol as well as lipid homeostasis. Regulates export of the SCAP/SREBF complex from the ER [...]
Fbxw18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095962F-box and WD-40 domain protein 18.
Adad2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095964Adenosine deaminase domain-containing protein 2; Belongs to the ADAD family.
Mbtps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095965Membrane-bound transcription factor site-1 protease; Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other [...]
Necab2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095966N-terminal EF-hand calcium-binding protein 2; May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling effici [...]
Mlycd protein networkhttps://string-db.org/network/10090.ENSMUSP00000095970Malonyl-CoA decarboxylase, mitochondrial; Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-ma [...]
Pkd1l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095977Polycystic kidney disease protein 1-like 2; May function as an ion-channel regulator. May function as a G-protein-coupled receptor (By similarity).
Slc26a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095979Solute carrier family 26 member 6; Apical membrane anion-exchanger with wide epithelial distribution that plays a role as a component of the pH buffering system for maintaining acid-base homeosta [...]
Adamts17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000095984A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17.
Snrpn protein networkhttps://string-db.org/network/10090.ENSMUSP00000096003Small nuclear ribonucleoprotein-associated protein N; May be involved in tissue-specific alternative RNA processing events.
Svip protein networkhttps://string-db.org/network/10090.ENSMUSP00000096014Small VCP/p97-interacting protein; Belongs to the SVIP family.
Col6a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096040Collagen alpha-6(VI) chain; Collagen VI acts as a cell-binding protein; Belongs to the type VI collagen family.
Il20rb protein networkhttps://string-db.org/network/10090.ENSMUSP00000096057Interleukin 20 receptor beta.
1700057G04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000096077Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry i [...]
Bcl2a1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000096086Bcl-2-related protein A1; Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infec [...]
Bcl2a1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000096087B-cell leukemia/lymphoma 2 related protein A1d.
Snap91 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096096Clathrin coat assembly protein AP180; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to i [...]
AW146154 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096109Expressed sequence AW146154.
Plekhf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096113Pleckstrin homology domain-containing family F member 1; May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosoma [...]
Cebpa protein networkhttps://string-db.org/network/10090.ENSMUSP00000096129CCAAT/enhancer-binding protein alpha; Transcription factor that coordinates proliferation arrest and the differentiation of myeloid progenitors, adipocytes, hepatocytes, and cells of the lung and [...]
Znhit6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096136Box C/D snoRNA protein 1; Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.
Gsta1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096139Glutathione S-transferase A1, N-terminally processed; Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide rang [...]
Odf2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000096140Protein BCAP; Acts as a suppressor of ciliogenesis, specifically, the initiation of ciliogenesis.
Scn1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000096148Sodium channel subunit beta-1; Regulatory subunit of multiple voltage-gated sodium channel complexes that play important roles in excitable membranes in brain, heart and skeletal muscle. Enhances [...]
Clca4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000096149Chloride channel calcium activated 7.
Krtdap protein networkhttps://string-db.org/network/10090.ENSMUSP00000096159Keratinocyte differentiation-associated protein; May act as a soluble regulator of keratinocyte differentiation. May play an important role in embryonic skin morphogenesis (By similarity).
Rap1gds1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096173RAP1, GTP-GDP dissociation stimulator 1.
Zfp280d protein networkhttps://string-db.org/network/10090.ENSMUSP00000096175Zinc finger protein 280D; May function as a transcription factor.
Ccdc130 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096177Coiled-coil domain-containing protein 130.
Mttp protein networkhttps://string-db.org/network/10090.ENSMUSP00000096179Microsomal triglyceride transfer protein large subunit; Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of p [...]
Sdhaf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096185Succinate dehydrogenase assembly factor 1, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) [...]
Cox7a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096193Cytochrome c oxidase subunit 7A1, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The r [...]
Zfp382 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096196Zinc finger protein 382; Functions as a sequence-specific transcriptional repressor.
Foxb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096197Forkhead box protein B1.
Spint2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096204Kunitz-type protease inhibitor 2; Inhibitor of HGF activator.
Ggn protein networkhttps://string-db.org/network/10090.ENSMUSP00000096209Gametogenetin; May be involved in spermatogenesis.
Zfp827 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096214Zinc finger protein 827; May be involved in transcriptional regulation.
Cib3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096231Calcium and integrin-binding family member 3.
Zfp974 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096238Zinc finger protein 974.
Prx protein networkhttps://string-db.org/network/10090.ENSMUSP00000096241Periaxin; Scaffolding protein that functions as part of a dystroglycan complex in Schwann cells, and as part of EZR and AHNAK-containing complexes in eye lens fiber cells. Required for the mainte [...]
Pias1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096248E3 SUMO-protein ligase PIAS1; Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Pla [...]
Cyp2a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096254Cytochrome P450 2A4; Highly active in the 15-alpha-hydroxylation of testosterone. Also active in the 15-alpha-hydroxylation of progesterone and androstenedione. Little or no activity on corticost [...]
Thsd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096257Thrombospondin type-1 domain-containing protein 4; Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active [...]
Gramd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096258GRAM domain-containing protein 2A; Participates in the organization ofendoplasmic reticulum- plasma membrane contact sites (EPCS) with pleiotropic functions including STIM1 recruitment and calciu [...]
Amy2a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096264Pancreatic alpha-amylase.
Ceacam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096266Carcinoembryonic antigen-related cell adhesion molecule 1; [Isoform 1]: Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner (By similarity). Plays a role [...]
Amy2a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096270Amylase 2a5.
Rec114 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096271Meiotic recombination protein REC114; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with IHO1/CCDC3 [...]
Ccdc33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096279Coiled-coil domain-containing protein 33.
Arhgef1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096280Rho guanine nucleotide exchange factor 1; Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activa [...]
Psd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096293PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.
Gm10663 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096312Predicted gene 10663.
Gm10665 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096316Vomeronasal type-1 receptor.
Vmn1r250 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096318Vomeronasal type-1 receptor.
Vmn1r114 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096333Taste receptor type 2.
Gm10670 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096340Predicted gene 10670.
Vmn1r93 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096343Vomeronasal 1 receptor 93.
Lrif1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096346Ligand-dependent nuclear receptor-interacting factor 1; Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin. Also able to repress [...]
I830077J02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000096354Transmembrane protein C1orf162 homolog.
Tnfaip8l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096356Tumor necrosis factor alpha-induced protein 8-like protein 3; Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- b [...]
Ccdc61 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096377Coiled-coil domain-containing protein 61.
Layn protein networkhttps://string-db.org/network/10090.ENSMUSP00000096379Layilin; Receptor for hyaluronate.
Zc3h4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096386Zinc finger CCCH domain-containing protein 4.
Ehd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096397EH domain-containing protein 2; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in membrane trafficking between the plasma mem [...]
Crxos protein networkhttps://string-db.org/network/10090.ENSMUSP00000096399Cone-rod homeobox, opposite strand.
Obox5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096400Oocyte-specific homeobox 5.
Sult2a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096407Sulfotransferase; Belongs to the sulfotransferase 1 family.
Bsph1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096408Binder of sperm protein homolog 1; Binds sperm in vitro and promotes sperm capacitation. Specifically promotes capacitation induced by high density lipoproteins (HDLs). Also binds heparin, phosph [...]
Vps37a protein networkhttps://string-db.org/network/10090.ENSMUSP00000096415Vacuolar protein sorting-associated protein 37A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into mu [...]
Zfp606 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096421Zinc finger protein 606.
Foxr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096436Forkhead box protein R1.
H3c13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096442H3 clustered histone 13.
Epn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096445Epsin-1; Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By simi [...]
Kcnu1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096457Potassium channel subfamily U member 1; Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). Represents the primary spermatozoan [...]
Tnni3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096458Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Gm21750 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096471Predicted gene, 21750.
Spopfm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096477Speckle-type BTB/POZ protein family member 1.
Tdpoz5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096478TD and POZ domain containing 5.
Flg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096482Filaggrin-2; Essential for normal cell-cell adhesion in the cornified cell layers. Important for proper integrity and mechanical strength of the stratum corneum of the epidermis; Belongs to the S [...]
Lce3e protein networkhttps://string-db.org/network/10090.ENSMUSP00000096484Late cornified envelope 3E.
Defa28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096486Defensin, alpha, 28.
Smcp protein networkhttps://string-db.org/network/10090.ENSMUSP00000096487Sperm mitochondrial-associated cysteine-rich protein; Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced s [...]
Defa29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096489Alpha-defensin-related sequence 1; Apparent precursor of a secreted, cationic, proline- and cysteine-rich peptide that contains Cys-Pro-Xaa repeats. Unlike cryptdin, the proposed mature peptide r [...]
Defa5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096491Alpha-defensin 5.
Defa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096492Defensin, alpha, 3.
Defa40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096494Defensin, alpha, 40.
Defa31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096495Alpha-defensin 23; May have microbicidal activities; Belongs to the alpha-defensin family.
Defa22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096496Alpha-defensin 22.
Defa30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096497Defensin, alpha, 30.
Defa23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096498Defensin, alpha, 23.
Pate9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096499Prostate and testis-expressed 9.
Defb33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096507Beta-defensin 33; Has antibacterial activity; Belongs to the beta-defensin family.
4930467E23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000096508RIKEN cDNA 4930467E23 gene.
S100a16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096510Protein S100-A16; Calcium-binding protein. Binds one calcium ion per monomer. Can promote differentiation of adipocytes (in vitro). Overexpression in 3T3-L1 preadipocytes increases their prolifer [...]
Dennd4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000096514DENN domain-containing protein 4B; Guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP- bound Rab proteins into their a [...]
AF366264 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096518cDNA sequence AF366264.
Spc24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096541Kinetochore protein Spc24; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for ki [...]
Smarca4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096547Transcription activator BRG1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin [...]
Elavl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096549ELAV-like protein 1; RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability. Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNA [...]
Bglap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096555Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family.
Cep295 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096578Centrosomal protein of 295 kDa; Centriole-enriched microtubule-binding protein involved in centriole biogenesis. Essential for the generation of the distal portion of new-born centrioles in a CEN [...]
Gm14296 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096605RIKEN cDNA 2210418O10 gene.
2210418O10Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000096607RIKEN cDNA 2210418O10 gene.
Gm10717 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096644Predicted gene 10717.
Gm10718 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096645Predicted gene 10718.
Gm10719 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096646Predicted gene 10719.
Gm10720 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096649Predicted gene 10720.
Gcnt7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096659Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7; Glycosyltransferase; Belongs to the glycosyltransferase 14 family.
Mocs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096670Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential durin [...]
Ripor3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096672RIPOR family member 3; Belongs to the RIPOR family.
Lekr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096674Leucine, glutamate and lysine-rich 1.
Arfgef2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096677Brefeldin A-inhibited guanine nucleotide-exchange protein 2; Promotes guanine-nucleotide exchange on ARF1 and ARF3 and to a lower extent on ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF [...]
Mbnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096686Muscleblind-like protein 1; Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) [...]
Tsc22d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096688TSC22 domain family, member 2.
Ankub1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096689Protein ANKUB1.
Slc12a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096690Solute carrier family 12 member 5; Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chlo [...]
Wfdc6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000096694WAP four-disulfide core domain protein 6A.
Spint3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096695Serine peptidase inhibitor, Kunitz type, 3.
Pabpc1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000096701Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
Mgst2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096705Microsomal glutathione S-transferase 2.
Itga7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096712Integrin alpha-7 heavy chain; Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shap [...]
Mafb protein networkhttps://string-db.org/network/10090.ENSMUSP00000096728Transcription factor MafB; Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythro [...]
Tgif2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096745Homeobox protein TGIF2; Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. [...]
Tmem267 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096751Transmembrane protein 267.
Nnt protein networkhttps://string-db.org/network/10090.ENSMUSP00000096753NAD(P) transhydrogenase, mitochondrial; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity [...]
Sox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096755Transcription factor SOX-2; Transcription factor that forms a trimeric complex with POU5F1 (OCT3/4) on DNA and controls the expression of a number of genes involved in embryonic development such [...]
Ddx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096769ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline [...]
Gm1527 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096773Predicted gene 1527.
Kif5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000096775Kinesin heavy chain isoform 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusi [...]
Eif2s2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096777Eukaryotic translation initiation factor 2 subunit 2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S [...]
Tspyl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096799TSPY-like 3; Belongs to the nucleosome assembly protein (NAP) family.
Pde7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000096800High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle [...]
Foxs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096806Forkhead box protein S1; Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature.
Defb25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096809Beta-defensin 25; Has antibacterial activity; Belongs to the beta-defensin family.
Defb26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096811Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
Defb23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096812Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
Zcchc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096813Zinc finger CCHC domain-containing protein 3; Nucleic acid-binding protein involved in innate immune response to DNA and RNA viruses. Binds DNA and RNA in the cytoplasm and acts by promoting reco [...]
Csnk2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096829Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C- [...]
Ccl28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096847C-C motif chemokine 28; Chemotactic for resting CD4, CD8 T-cells and eosinophils (By similarity). Binds to CCR10 and induces calcium mobilization in a dose- dependent manner.
Taf7l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096867Taf7l2.
Fndc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096871Fibronectin type III domain-containing protein 10.
Nanos1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096874Nanos homolog 1; May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of inte [...]
Cd93 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096876Complement component C1q receptor; Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement [...]
Thbd protein networkhttps://string-db.org/network/10090.ENSMUSP00000096877Thrombomodulin; Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the ac [...]
Pdzd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096880PDZ domain-containing protein 8; Molecular tethering protein that connects endoplasmic reticulum and mitochondria membranes. PDZD8-dependent endoplasmic reticulum-mitochondria membrane tethering [...]
Atxn7l3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000096882Ataxin-7-like protein 3B; By binding to ENY2, interferes with the nuclear functions of the deubiquitinase (DUB) module of the SAGA complex which consists of ENY2, ATXN7, ATXN7L3 and the histone d [...]
Kiz protein networkhttps://string-db.org/network/10090.ENSMUSP00000096884Centrosomal protein kizuna; Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle forma [...]
Poc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096898Centrosomal protein POC5; Essential for the assembly of the distal half of centrioles, required for centriole elongation.
Bfsp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096899Filensin C-terminal fragment; Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA (By similarity). Involved in altering the c [...]
Bhmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000096912Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reactio [...]
Slx4ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000096914Protein SLX4IP; Belongs to the SLX4IP family.
Rasgrf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096930Ras-specific guanine nucleotide-releasing factor 2; Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentia [...]
Anapc15-ps protein networkhttps://string-db.org/network/10090.ENSMUSP00000096931Anaphase prompoting complex C subunit 15, pseudogene.
Ube2n protein networkhttps://string-db.org/network/10090.ENSMUSP00000096932Ubiquitin-conjugating enzyme E2 N; The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination doe [...]
Plxnc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096939Plexin-C1; Receptor for SEMA7A, for vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoske [...]
Hspa12b protein networkhttps://string-db.org/network/10090.ENSMUSP00000096950Heat shock 70 kDa protein 12B.
Sfr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096954Swi5-dependent recombination DNA repair protein 1 homolog; Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. Acts as a transcript [...]
Arrdc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096957Arrestin domain-containing protein 3; Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein- coupled receptors. Plays a [...]
Slc4a11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096963Sodium bicarbonate transporter-like protein 11; Transporter which plays an important role in sodium-mediated fluid transport in different organs. Prevents severe morphological changes of the corn [...]
Cnnm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096972Metal transporter CNNM2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+); Belongs to th [...]
Gas2l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096973GAS2-like protein 3; Cytoskeletal linker protein. May promote and stabilize the formation of the actin and microtubule network (By similarity). Belongs to the GAS2 family.
Wbp1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000096975WW domain binding protein 1-like.
Brd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096982Bromodomain-containing protein 9; Plays a role in chromatin remodeling and regulation of transcription. Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that [...]
Hps6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096991Hermansky-Pudlak syndrome 6 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules (By similar [...]
Nt5dc3 protein networkhttps://string-db.org/network/10090.ENSMUSP000000969945'-nucleotidase domain-containing protein 3.
Lbx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000096997Transcription factor LBX1; Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial musc [...]
Zfp955b protein networkhttps://string-db.org/network/10090.ENSMUSP00000097011Zinc finger protein 955B.
Spata31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097025Spermatogenesis-associated protein 31; May play a role in spermatogenesis.
Hpse2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097026Inactive heparanase-2; Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro) (By similarity).
Slc35d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097040UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Ma [...]
BC025920 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097041cDNA sequence BC025920.
Zfp808 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097048Zinc finger protein 808.
Ctxn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097051Cortexin-2.
Duox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097060Dual oxidase 1.
Gng7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097061Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling sy [...]
Cyp2c68 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097071Cytochrome P450, family 2, subfamily c, polypeptide 68; Belongs to the cytochrome P450 family.
Serf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097074Small EDRK-rich factor 2; Positive regulator of amyloid protein aggregation and proteotoxicity (By similarity). Induces conformational changes in amyloid proteins, such as HTT, driving them into [...]
Nsd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097089Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that dimethylates Lys-36 of histone H3 (H3K36me2). Transcriptional intermediary factor capable of negatively i [...]
Btaf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097093B-TFIID TATA-box-binding protein-associated factor 1.
Ccdc80 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097097Coiled-coil domain-containing protein 80; Promotes cell adhesion and matrix assembly.
Brwd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097101Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling. Plays a role in the regulation of cell morphology and cytoskeletal org [...]
Htr7 protein networkhttps://string-db.org/network/10090.ENSMUSP000000971055-hydroxytryptamine receptor 7; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mito [...]
Kcnj6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097108G protein-activated inward rectifier potassium channel 2; This potassium channel is controlled by G proteins. It plays a role in granule cell differentiation, possibly via membrane hyperpolarizat [...]
Hcn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097113Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2; Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to [...]
Fam8a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097144Family with sequence similarity 8, member A1.
Mis18a protein networkhttps://string-db.org/network/10090.ENSMUSP00000097150Protein Mis18-alpha; Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
Fam122a protein networkhttps://string-db.org/network/10090.ENSMUSP00000097152Protein FAM122A; Acts as an inhibitor of serine/threonine-protein phosphatase 2A (PP2A) activity. Potentiates ubiquitin-mediated proteasomal degradation of serine/threonine-protein phosphatase 2A [...]
Pak6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097153Serine/threonine-protein kinase PAK 6; Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR [...]
Prmt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097167Protein arginine N-methyltransferase 2; Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. May inhibit NF-kappa-B t [...]
Grem1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097170Gremlin-1; Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining [...]
Gm5134 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097172Predicted gene 5134; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Chrm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097185Muscarinic acetylcholine receptor M5; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modu [...]
Olfr1316 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097191Olfactory receptor.
Olfr1307 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097199Olfactory receptor.
Olfr1282 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097213Olfactory receptor.
Ano3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097219Anoctamin-3; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylcholine and galactosylceramide. Does not exhibit calcium-activated chloride channel (CaCC) activity. See [...]
Fibin protein networkhttps://string-db.org/network/10090.ENSMUSP00000097221Fin bud initiation factor homolog.
Arl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097238ADP-ribosylation factor-like protein 6; Involved in membrane protein trafficking at the base of the ciliary organelle (By similarity). Mediates recruitment onto plasma membrane of the BBSome comp [...]
Nrbf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097254Nuclear receptor-binding factor 2; May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro) (By similarity). Involved in the induction [...]
Gm813 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097255Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Gm7075 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097258Predicted gene 7075.
Fjx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097270Four-jointed box protein 1; Acts as an inhibitor of dendrite extension and branching. Belongs to the FJX1/FJ family.
Gm10800 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097275Predicted gene 10800.
Gm10801 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097276Predicted gene 10801.
Accsl protein networkhttps://string-db.org/network/10090.ENSMUSP00000097281Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2.
H2bc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097294Histone H2B type 1-B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
Nxpe3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097296Neurexophilin and PC-esterase domain family, member 3.
Zfp408 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097301Zinc finger protein 408.
Pgbd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097307PiggyBac transposable element-derived 1.
Gm4981 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097314Predicted gene, EG245263.
Lgals12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097318Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes.
Yae1d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097324Yae1 domain-containing 1.
Tbc1d32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097328Protein broad-minded; Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliar [...]
Cfap44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097331Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP44 family.
B3galnt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097336UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2; Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O- glycans. [...]
Lsamp protein networkhttps://string-db.org/network/10090.ENSMUSP00000097349Limbic system-associated membrane protein; Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic s [...]
Olfr1230 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097375Olfactory receptor MOR237-1.
Prl2c3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097393Prolactin-2C3; May have a role in embryonic development. It is likely to provide a growth stimulus to target cells in maternal and fetal tissues during the development of the embryo at mid-gestat [...]
Olfr1164 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097422Olfactory receptor.
Olfr1160 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097427Olfactory receptor.
Olfr74 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097428Olfactory receptor.
Olfr1157 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097429Olfactory receptor.
Olfr1141 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097433Olfactory receptor MOR177-10; Belongs to the G-protein coupled receptor 1 family.
Mtr protein networkhttps://string-db.org/network/10090.ENSMUSP00000097442Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor us [...]
Prep protein networkhttps://string-db.org/network/10090.ENSMUSP00000097444Prolyl endopeptidase; Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.
Olfr1095 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097459Olfactory receptor.
Olfr1079 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097467Olfactory receptor.
Olfr1066 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097470Olfactory receptor 1066.
Olfr1061 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097474Olfactory receptor.
Olfr1053 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097481Olfactory receptor.
Olfr1048 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097484Olfactory receptor.
Olfr1040 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097493Olfactory receptor.
Olfr1024 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097496Olfactory receptor.
Olfr154 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097502Olfactory receptor 154; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Fads2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000097507Fatty acid desaturase 2-like protein FADS2P1.
Olfr993 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097510Olfactory receptor.
Sesn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097515Sestrin-1; Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 a [...]
Gm13691 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097530Predicted gene 13691.
Gm13697 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097531Predicted gene 13697.
Gm13695 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097534Predicted gene 13695.
Fam89b protein networkhttps://string-db.org/network/10090.ENSMUSP00000097538Leucine repeat adapter protein 25; Negatively regulates TGF-beta-induced signaling; in cooperation with SKI prevents the translocation of SMAD2 from the nucleus to the cytoplasm in response to TG [...]
Fyn protein networkhttps://string-db.org/network/10090.ENSMUSP00000097547Tyrosine-protein kinase Fyn; Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated [...]
Cenpw protein networkhttps://string-db.org/network/10090.ENSMUSP00000097565Centromere protein W; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segre [...]
Pjvk protein networkhttps://string-db.org/network/10090.ENSMUSP00000097566Pejvakin; Essential in the activity of auditory pathway neurons; Belongs to the gasdermin family.
Pde11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000097572Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A; Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolys [...]
Ttc30a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097574Tetratricopeptide repeat protein 30A1; Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are tr [...]
Ttc30a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097575Tetratricopeptide repeat protein 30A2; Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are tr [...]
Ttc30b protein networkhttps://string-db.org/network/10090.ENSMUSP00000097576Tetratricopeptide repeat protein 30B; Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are tra [...]
Pitpnm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097599Membrane-associated phosphatidylinositol transfer protein 1; Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in [...]
Mb21d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097600Protein MB21D2; Belongs to the mab-21 family.
Fgf12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097601Fibroblast growth factor 12; Involved in nervous system development and function. Promote neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivat [...]
Taar6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097603Trace amine-associated receptor 6; Orphan olfactory receptor specific for trace amines. Belongs to the G-protein coupled receptor 1 family.
Ccdc50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097604Coiled-coil domain-containing protein 50; Involved in EGFR signaling.
4930444G20Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000097613RIKEN cDNA 4930444G20 gene.
Erich2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097619Glutamate-rich 2.
Sp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097620Transcription factor Sp5; Binds to GC boxes promoters elements. Probable transcriptional activator that has a role in the coordination of changes in transcription required to generate pattern in [...]
Kng2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097623HMW kininogen-II.
Klhl41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097627Kelch-like protein 41; Involved in skeletal muscle development and differentiation. Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting la [...]
Igf2bp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097629Insulin-like growth factor 2 mRNA-binding protein 2; RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows m [...]
Scn9a protein networkhttps://string-db.org/network/10090.ENSMUSP00000097642Sodium channel protein type 9 subunit alpha; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage diff [...]
Scn3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000097647Sodium channel protein type 3 subunit alpha; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage diff [...]
Samd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097648Sterile alpha motif domain-containing protein 5.
Zbtb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097656Zinc finger and BTB domain-containing 2.
Rprm protein networkhttps://string-db.org/network/10090.ENSMUSP00000097667Protein reprimo; May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC [...]
Lrrc74b protein networkhttps://string-db.org/network/10090.ENSMUSP00000097699Leucine-rich repeat-containing protein 74B.
Thap7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097701THAP domain-containing protein 7; Chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressors.
Igll1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097713Immunoglobulin lambda-like polypeptide 1; Critical for B-cell development.
Rc3h2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097721Roquin-2; Post-transcriptional repressor of mRNAs containing a conserved stem loop motif, called constitutive decay element (CDE), which is often located in the 3'-UTR, as in HMGXB3, ICOS, IER3, [...]
Copz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097738Coatomer subunit zeta-1; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosyn [...]
Hoxc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097740Homeobox protein Hox-C4; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Abcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097743Multidrug resistance-associated protein 1; Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene [...]
Krt76 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097754Keratin, type II cytoskeletal 2 oral; Probably contributes to terminal cornification.
Golga2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097768Golgin subfamily A member 2; Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether th [...]
Alg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097770Chitobiosyldiphosphodolichol beta-mannosyltransferase; Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyropho [...]
Rnf157 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097776E3 ubiquitin ligase Rnf157; E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the proteasome and thus prevents apoptosis and promotes survival of neurons. Has a dual role in neu [...]
Dip2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000097777Disco-interacting protein 2 homolog B.
Larp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097780La-related protein 4; RNA binding protein that binds to the poly-A tract of mRNA molecules. Associates with the 40S ribosomal subunit and with polysomes. Plays a role in the regulation of mRNA tr [...]
4930562C15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000097784Uncharacterized protein C16orf96 homolog.
Miga2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097787Mitoguardin 2; Regulator of mitochondrial fusion. Acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regu [...]
Dolk protein networkhttps://string-db.org/network/10090.ENSMUSP00000097792Dolichol kinase; Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors.
Spout1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097793Putative methyltransferase C9orf114 homolog; Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase. Also involved in chromosome alignment. May [...]
Mefv protein networkhttps://string-db.org/network/10090.ENSMUSP00000097795Pyrin; Involved in the regulation of innate immunity and the inflammatory response in response to IFNG/IFN-gamma. Organizes autophagic machinery by serving as a platform for the assembly of ULK1, [...]
Ttf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097809Transcription termination factor 1; Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription o [...]
Cd300ld5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097810CD300 molecule-like family member D4.
Cd300ld4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097811CD300 molecule like family member D4.
Ralgds protein networkhttps://string-db.org/network/10090.ENSMUSP00000097812Ral guanine nucleotide dissociation stimulator; Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the GTPases. Interacts and [...]
Cpsf4l protein networkhttps://string-db.org/network/10090.ENSMUSP00000097819Cleavage and polyadenylation-specific factor 4-like.
Zfp788 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097847Zinc finger protein 788.
Prkcg protein networkhttps://string-db.org/network/10090.ENSMUSP00000097874Protein kinase C gamma type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such [...]
Card9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097876Caspase recruitment domain-containing protein 9; Adapter protein that plays a key role in innate immune response to a number of intracellular pathogens, such as C.albicans and L.monocytogenes. Is [...]
Alg10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000097882Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase; Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide pre [...]
Bmyc protein networkhttps://string-db.org/network/10090.ENSMUSP00000097885Protein B-Myc; Seems to act as an inhibitor of cellular proliferation.
Cldn10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097889Claudin-10; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in the regulation of paracellular e [...]
Fut7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097895Alpha-(1,3)-fucosyltransferase 7; Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal alpha2,3 sialylated lactosamine [...]
Slitrk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097897SLIT and NTRK-like protein 1; It is involved in synaptogenesis and promotes excitatory synapse differentiation (By similarity). Enhances neuronal dendrite outgrowth ; Belongs to the SLITRK family [...]
Rbm26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097901RNA-binding protein 26.
Tanc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097904Protein TANC2; Scaffolding protein in the dendritic spines which acts as immobile postsynaptic posts able to recruit KIF1A-driven dense core vesicles to dendritic spines; Belongs to the TANC fami [...]
Nsmf protein networkhttps://string-db.org/network/10090.ENSMUSP00000097908NMDA receptor synaptonuclear signaling and neuronal migration factor; Couples NMDA-sensitive glutamate receptor signaling to the nucleus and triggers long-lasting changes in the cytoarchitecture [...]
Mrc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097909C-type mannose receptor 2; May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release [...]
Lmo7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097910LIM domain only 7.
Commd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097912COMM domain-containing protein 6; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Inhibits TNF-induced NFKB1 activation.
Mapt protein networkhttps://string-db.org/network/10090.ENSMUSP00000097919Microtubule-associated protein.
Rbmy protein networkhttps://string-db.org/network/10090.ENSMUSP00000097930RNA-binding motif protein, Y chromosome, family 1 member A1; RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclus [...]
Fam187a protein networkhttps://string-db.org/network/10090.ENSMUSP00000097938Ig-like V-type domain-containing protein FAM187A.
Meioc protein networkhttps://string-db.org/network/10090.ENSMUSP00000097947Meiosis-specific coiled-coil domain-containing protein MEIOC; Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing [...]
BC030867 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097961Uncharacterized protein C17orf53 homolog.
4930407I10Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000097965RIKEN cDNA 4930407I10 gene.
Xrcc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000097968X-ray repair cross-complementing protein 6; Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork- [...]
Tmem106a protein networkhttps://string-db.org/network/10090.ENSMUSP00000097971Transmembrane protein 106A; Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway. Upon activation, upregulates the [...]
B3glct protein networkhttps://string-db.org/network/10090.ENSMUSP00000097972Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of protein [...]
Urad protein networkhttps://string-db.org/network/10090.ENSMUSP000000980002-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; Catalyzes the stereoselective decarboxylation of 2-oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.
Trrap protein networkhttps://string-db.org/network/10090.ENSMUSP00000098035Transformation/transcription domain-associated protein; Adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a sp [...]
Kif13b protein networkhttps://string-db.org/network/10090.ENSMUSP00000098041Kinesin family member 13B.
Gm11567 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098043Predicted gene 11567.
Krtap4-6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098045Keratin associated protein 4-6.
Krtap1-4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098048Keratin-associated protein 1-4.
Krt26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098051Keratin, type I cytoskeletal 26; Belongs to the intermediate filament family.
Eif3d protein networkhttps://string-db.org/network/10090.ENSMUSP00000098053Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the ini [...]
Eif2ak1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098056Eukaryotic translation initiation factor 2-alpha kinase 1; Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, he [...]
Rac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098058Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of [...]
Defb43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098060Beta-defensin 43; Has bactericidal activity; Belongs to the beta-defensin family.
Defb47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098061Predicted gene, EG654465.
Defb48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098062Predicted gene, EG432867.
Actb protein networkhttps://string-db.org/network/10090.ENSMUSP00000098066Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (By similarity). [...]
Brat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098074BRCA1-associated ATM activator 1; Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress. Play [...]
Eif3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000098076Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiatio [...]
Gpr146 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098083Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Hoxb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098092Homeobox protein Hox-B2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Puf60 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098096Poly(U)-binding-splicing factor PUF60; DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with F [...]
Ube2z protein networkhttps://string-db.org/network/10090.ENSMUSP00000098097Ubiquitin-conjugating enzyme E2 Z; Catalyzes the covalent attachment of ubiquitin to other proteins. Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis [...]
Gal3st4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098099Galactose-3-O-sulfotransferase 4.
Smok3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000098105Sperm motility kinase 3B.
Zc3h3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098106Zinc finger CCCH domain-containing protein 3; Required for the export of polyadenylated mRNAs from the nucleus (By similarity). Enhances ACVR1B-induced SMAD-dependent transcription. Binds to sing [...]
Tsc22d4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098108TSC22 domain family protein 4; Transcriptional repressor; Belongs to the TSC-22/Dip/Bun family.
Ly6c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098110Lymphocyte antigen 6C2.
Agfg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098112Arf-GAP domain and FG repeat-containing protein 2.
Cacna1g protein networkhttps://string-db.org/network/10090.ENSMUSP00000098127Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calc [...]
Hhla1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098149HERV-H LTR-associating protein 1 homolog.
Gm525 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098184Uncharacterized protein C17orf67 homolog.
Lratd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098200LRAT domain-containing 1.
Tmem253 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098203Transmembrane protein 253.
Gm6526 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098208Predicted gene 6526.
Eddm3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000098210Epididymal protein 3B.
Clip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098212CAP-Gly domain-containing linker protein 2; Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons li [...]
Gtf2ird1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098217General transcription factor II-I repeat domain-containing protein 1; May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I tr [...]
9130401M01Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000098220Uncharacterized protein C8orf76 homolog.
Csmd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098235CUB and sushi domain-containing protein 3; Involved in dendrite development.
4930503E14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000098254RIKEN cDNA 4930503E14 gene.
Ear1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098256Eosinophil cationic protein 1; Cytotoxin and helminthotoxin with ribonuclease activity. Possesses a wide variety of biological activities (By similarity). Belongs to the pancreatic ribonuclease f [...]
Gm10377 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098260Predicted gene 10376.
Gm3633 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098262Predicted gene 3633.
Kmt5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000098275N-lysine methyltransferase KMT5A; Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K [...]
Gdf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098286Growth/differentiation factor 2; Potent circulating inhibitor of angiogenesis (By similarity). Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in en [...]
1700024G13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000098289UPF0728 protein C10orf53 homolog; Belongs to the UPF0728 family.
Psmd9 protein networkhttps://string-db.org/network/10090.ENSMUSP0000009829526S proteasome non-ATPase regulatory subunit 9; Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). During [...]
P2rx7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098303P2X purinoceptor 7; Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecul [...]
Otulinl protein networkhttps://string-db.org/network/10090.ENSMUSP00000098305Inactive ubiquitin thioesterase OTULINL; Lacks deubiquitinase activity.
Hvcn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098312Voltage-gated hydrogen channel 1; Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with the [...]
Adam1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000098320Disintegrin and metalloproteinase domain-containing protein 1a; May be involved in sperm-egg fusion.
Mansc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098343MANSC domain-containing protein 4.
Nufip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098365Nuclear fragile X mental retardation-interacting protein 2; Binds RNA.
Duxbl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098367Double homeobox B-like 3.
Tmem254b protein networkhttps://string-db.org/network/10090.ENSMUSP00000098369Transmembrane protein 254.
Duxbl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098373Double homeobox B-like 2.
Tmem254a protein networkhttps://string-db.org/network/10090.ENSMUSP00000098374Transmembrane protein 254a.
Tmem254c protein networkhttps://string-db.org/network/10090.ENSMUSP00000098381Transmembrane protein 254c.
Abcc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098390ATP-binding cassette sub-family C member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore wh [...]
1500011B03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000098411RIKEN cDNA 1500011B03 gene.
Pbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098414Phosphatidylethanolamine-binding protein 2; May bind to phospholipids. May act as serine protease inhibitor (By similarity).
Dusp16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098419Dual-specificity phosphatase 16.
Ccdc92b protein networkhttps://string-db.org/network/10090.ENSMUSP00000098429Coiled-coil domain-containing 92B.
Selplg protein networkhttps://string-db.org/network/10090.ENSMUSP00000098436P-selectin glycoprotein ligand 1; A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E- and P-selectins, mediates rapid rolling of leukocytes over vascul [...]
Gm6588 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098441Predicted gene 6588.
Gm16434 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098448Predicted gene 16434.
Tex52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098486Testis-expressed protein 52.
Gbp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098522Guanylate binding protein 4.1.
Vmn2r27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098528Vomeronasal 2, receptor27.
Esyt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098548Extended synaptotagmin-2; Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glyceroph [...]
Gm3259 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098577Predicted gene 3259.
Cep170b protein networkhttps://string-db.org/network/10090.ENSMUSP00000098580Centrosomal protein of 170 kDa protein B; Plays a role in microtubule organization.
Gm16513 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098585Predicted gene, Gm16513.
Inf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098591Inverted formin-2; Severs actin filaments and accelerates their polymerization and depolymerization; Belongs to the formin homology family.
March8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098594E3 ubiquitin-protein ligase MARCHF8; E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endoc [...]
Atp2b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098605Plasma membrane calcium-transporting ATPase 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell. Plays a role in maintaining b [...]
Prr27 protein networkhttps://string-db.org/network/10090.ENSMUSP000000986174930432K09Rik protein.
Jagn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098631Protein jagunal homolog 1; Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function. Required for vesicle-mediated transport; [...]
Tcl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098632T-cell leukemia/lymphoma protein 1A; Enhances the phosphorylation and activation of AKT1 and AKT2. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survi [...]
Tmprss11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000098634Transmembrane protease serine 11A; Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest; Belongs to the pepti [...]
Srp72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098648Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP7 [...]
Otub2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098655Ubiquitin thioesterase OTUB2; Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by prevent [...]
Unc79 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098659Protein unc-79 homolog; Component of the NALCN sodium channel complex, a cation channel activated either by neuropeptides substance P or neurotensin that controls neuronal excitability.
Reps2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098661RalBP1-associated Eps domain-containing protein 2; Involved in growth factor signaling through its influence on the Ral signaling pathway (By similarity). Interaction with ASAP1 may regulate cell [...]
Rybp protein networkhttps://string-db.org/network/10090.ENSMUSP00000098677RING1 and YY1-binding protein; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, inclu [...]
Gpr27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098680Probable G-protein coupled receptor 27; Orphan receptor. Possible candidate for amine-like G-protein coupled receptor (By similarity).
Lrig1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098686Leucine-rich repeats and immunoglobulin-like domains protein 1; Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of r [...]
Fryl protein networkhttps://string-db.org/network/10090.ENSMUSP00000098687FRY-like transcription coactivator.
Shroom2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098701Protein Shroom2; May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their asso [...]
Nlrp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098707NACHT, LRR and PYD domains-containing protein 3; As the sensor component of the NLRP3 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens and other da [...]
Iqsec1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098710IQ motif and SEC7 domain-containing protein 1; Guanine nucleotide exchange factor for ARF1 and ARF6. Guanine nucleotide exchange factor activity is enhanced by lipid binding. Accelerates GTP bind [...]
Limch1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098723LIM and calponin homology domains-containing protein 1; Actin stress fibers-associated protein that activates non- muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the [...]
Gm5662 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098728Predicted gene, EG435337; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 [...]
Gm15097 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098740Predicted gene 15097.
Gm10439 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098741Predicted gene 10439.
Gm15127 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098746Predicted gene 15127.
Klhl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098752Klhl5 protein.
Col4a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098765Collagen, type IV, alpha 6.
Sod3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098768Extracellular superoxide dismutase [Cu-Zn]; Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
Nup62cl protein networkhttps://string-db.org/network/10090.ENSMUSP00000098772Nucleoporin 62 C-terminal-like.
Ripply1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098778Protein ripply1; Plays a role in somitogenesis. Essential for transcriptional repression of the segmental patterning genes, thus terminating the segmentation program in the presomitic mesoderm, a [...]
Psen1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098786Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors [...]
Bst1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098796ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits ca [...]
Ccdc142 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098812Coiled-coil domain-containing protein 142.
Cpxcr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098827CPX chromosomal region candidate gene 1 protein homolog.
Tbc1d9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000098828TBC1 domain family member 9B; May act as a GTPase-activating protein for Rab family protein(s).
Reg3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000098829Regenerating islet-derived protein 3-alpha 16.5 kDa form; Bactericidal C-type lectin (By similarity). Regulates keratinocyte proliferation and differentiation after skin injury via activation of [...]
Cylc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098840Cylicin, basic protein of sperm head cytoskeleton 1.
Vamp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098843Vesicle-associated membrane protein 5; May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking; Belongs to the synaptobrevin fa [...]
Gm732 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098848Gene model 732, (NCBI).
Gm5127 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098855Predicted gene, EG331493.
Cited1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098890Cbp/p300-interacting transactivator 1; Transcriptional coactivator of the p300/CBP-mediated transcription complex. Enhances SMAD-mediated transcription by strengthening the functional link betwee [...]
Nhsl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098893NHS-like protein 2; Belongs to the NHS family.
Atoh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098903Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator o [...]
Gm614 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098910Uncharacterized protein CXorf65 homolog.
Hbq1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000098936Hemoglobin, theta 1B; Belongs to the globin family.
Chac2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098942Putative glutathione-specific gamma-glutamylcyclotransferase 2; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on ot [...]
Hoxa4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098943Homeobox protein Hox-A4; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Gm8914 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098944Predicted gene 8914.
Gm29609 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098957Predicted gene 29609.
Tmem176a protein networkhttps://string-db.org/network/10090.ENSMUSP00000098969Transmembrane protein 176A.
Npas3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098975Neuronal PAS domain-containing protein 3; May play a broad role in neurogenesis. May control regulatory pathways relevant to schizophrenia and to psychotic illness.
Smim9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098976Small integral membrane protein 9.
Kcnk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098987Potassium channel subfamily K member 3; pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of [...]
Zfp956 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098989Zinc finger protein 956.
Drc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000098992Dynein regulatory complex protein 1; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the dist [...]
Serpinb9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099002Serine (Or cysteine) peptidase inhibitor, clade B, member 9; Belongs to the serpin family.
Peli1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099018E3 ubiquitin-protein ligase pellino homolog 1; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity). Involved in the TLR and IL-1 s [...]
Xlr3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000099026X-linked lymphocyte-regulated protein 3B; Belongs to the XLR/SYCP3 family.
Gm1141 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099034Predicted gene 1141.
Cbll1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099038E3 ubiquitin-protein ligase Hakai; E3 ubiquitin-protein ligase that mediates ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endo [...]
Tmem185a protein networkhttps://string-db.org/network/10090.ENSMUSP00000099043Transmembrane protein 185A.
Ids protein networkhttps://string-db.org/network/10090.ENSMUSP00000099046Iduronate 2-sulfatase; Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate.
Atp11c protein networkhttps://string-db.org/network/10090.ENSMUSP00000099066Phospholipid-transporting ATPase 11C; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to th [...]
Dgki protein networkhttps://string-db.org/network/10090.ENSMUSP00000099071Diacylglycerol kinase.
Ptn protein networkhttps://string-db.org/network/10090.ENSMUSP00000099073Pleiotrophin; Secreted growth factor that mediates its signal through cell- surface proteoglycan and non-proteoglycan receptors (By similarity). Binds cell-surface proteoglycan receptor via their [...]
9030624G23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000099077RIKEN cDNA 9030624G23 gene.
Zfp934 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099083Zinc finger protein 934.
Adam17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099087Disintegrin and metalloproteinase domain-containing protein 17; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble [...]
Zfp449 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099096Zinc finger protein 449.
Gm773 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099097Gene model 773, (NCBI).
Ccdc160 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099121Coiled-coil domain-containing protein 160; Belongs to the CCDC160 family.
Klf14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099122Krueppel-like factor 14.
Rhbdd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099131Rhomboid domain-containing protein 3.
Kcp protein networkhttps://string-db.org/network/10090.ENSMUSP00000099135Kielin/chordin-like protein; Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways.
Smarca1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099138Probable global transcription activator SNF2L1; Energy-transducing component of the NURF (nucleosome- remodeling factor) and CERF (CECR2-containing-remodeling factor) complexes, which facilitate [...]
Gm9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099160Predicted gene 9.
Limk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099162LIM domain kinase 2; Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pa [...]
Gm14819 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099168Predicted gene 14819.
Gm14632 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099177Predicted gene 14632.
Gm10491 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099217Predicted gene 10491.
Msrb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099300Methionine-R-sulfoxide reductase B1; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result [...]
Selenos protein networkhttps://string-db.org/network/10090.ENSMUSP00000099301Selenoprotein S; Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where [...]
Tbcd protein networkhttps://string-db.org/network/10090.ENSMUSP00000099302Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtub [...]
Narf protein networkhttps://string-db.org/network/10090.ENSMUSP00000099304Nuclear prelamin A recognition factor; Belongs to the NARF family.
Slc38a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099307Putative sodium-coupled neutral amino acid transporter 10; Putative sodium-dependent amino acid/proton antiporter.
Cep295nl protein networkhttps://string-db.org/network/10090.ENSMUSP00000099313CEP295 N-terminal-like protein.
Mgat5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000099316Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B; Glycosyltransferase that acts on alpha-linked mannose of N- glycans and O-mannosyl glycans. Catalyzes the transfer of N- a [...]
Rhbdf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099317Inactive rhomboid protein 2; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migr [...]
Fbf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099320Fas-binding factor 1; Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenes [...]
Kctd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099324BTB/POZ domain-containing protein KCTD2.
Ush1g protein networkhttps://string-db.org/network/10090.ENSMUSP00000099326Usher syndrome type-1G protein homolog; Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network forme [...]
Nat9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099329N-acetyltransferase 9; Belongs to the acetyltransferase family. GNAT subfamily.
Tcea2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099331Transcription elongation factor A protein 2; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property [...]
Stmn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099334Stathmin-3; Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.
Nkain4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099342Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4; Belongs to the NKAIN family.
Wipi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099349WD repeat domain phosphoinositide-interacting protein 1; Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged [...]
Pitpnc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099353Cytoplasmic phosphatidylinositol transfer protein 1; Phosphatidylinositol transfer proteins mediate the monomeric transport of lipids by shielding a lipid from the aqueous environment and binding [...]
Gh protein networkhttps://string-db.org/network/10090.ENSMUSP00000099360Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentia [...]
Nsf protein networkhttps://string-db.org/network/10090.ENSMUSP00000099364Vesicle-fusing ATPase; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulu [...]
Spata32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099365Spermatogenesis-associated protein 32.
Plcd3 protein networkhttps://string-db.org/network/10090.ENSMUSP000000993661-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and in [...]
Cttn protein networkhttps://string-db.org/network/10090.ENSMUSP00000099368Src substrate cortactin; Contributes to the organization of the actin cytoskeleton and cell shape. Plays a role in the formation of lamellipodia and in cell migration (By similarity). Plays a rol [...]
Zfp334 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099373Zinc finger protein 334.
Zfp663 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099374Gene model 1008, (NCBI).
Itga2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000099375Integrin alpha-IIb heavy chain; Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in [...]
Ctsa protein networkhttps://string-db.org/network/10090.ENSMUSP00000099381Lysosomal protective protein 20 kDa chain; Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a [...]
Acot8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099383Acyl-coenzyme A thioesterase 8; Acyl-coenzyme A (acyl-CoA) thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing [...]
Tnnc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099384Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T whi [...]
Wfdc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099385WAP four-disulfide core domain protein 3.
Spint5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099386Serine protease inhibitor, Kunitz type 5.
Nbr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099388Next to BRCA1 gene 1 protein; Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.
Eppin protein networkhttps://string-db.org/network/10090.ENSMUSP00000099389Eppin; Serine protease inhibitor that plays an essential role in male reproduction and fertility. Modulates the hydrolysis of SEMG1 by KLK3/PSA (a serine protease), provides antimicrobial protect [...]
Pigt protein networkhttps://string-db.org/network/10090.ENSMUSP00000099390GPI transamidase component PIG-T; Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates (By similarity).
Ptges3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000099391Putative protein PTGES3L.
Matn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099392Matrilin-4; Major component of the extracellular matrix of cartilage.
Aoc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099394Membrane primary amine oxidase; Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in [...]
Cntd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099396Cyclin N-terminal domain-containing protein 1.
Wnk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099397Serine/threonine-protein kinase WNK4; Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an ac [...]
Cntnap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099398Contactin-associated protein 1; Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for sal [...]
Atp6v0a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099399V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific o [...]
Zhx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099400Zinc fingers and homeoboxes protein 3; Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene [...]
Plcg1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000994041-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an [...]
Kat2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000099407Histone acetyltransferase KAT2A; Protein lysine acyltransferase that can act as a acetyltransferase, glutaryltransferase or succinyltransferase, depending on the context. Acts as a histone lysine [...]
Zfp385c protein networkhttps://string-db.org/network/10090.ENSMUSP00000099408Zinc finger protein 385C.
Cnp protein networkhttps://string-db.org/network/10090.ENSMUSP000000994092',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
Tgm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099411Protein-glutamine gamma-glutamyltransferase 2; Catalyzes the cross-linking of proteins, such as WDR54, and the conjugation of polyamines to proteins. Belongs to the transglutaminase superfamily. [...]
Krt35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099416Keratin, type I cuticular Ha5.
Dsn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099419Kinetochore-associated protein DSN1 homolog; Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis.
Krt10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099420Keratin, type I cytoskeletal 10; Plays a role in the establishment of the epidermal barrier on plantar skin. (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to [...]
Krt222 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099421Keratin-like protein KRT222.
Smarce1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099422SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alter [...]
Ccr7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099423C-C chemokine receptor type 7; Receptor for the MIP-3-beta chemokine.
Ikzf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099430Zinc finger protein Aiolos; Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Binds to GGGAA. Plays an essential role in regulation of B-cell diff [...]
Fbxl20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099432F-box/LRR-repeat protein 20; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Isoform 3 regulates neural transmission by binding and ubiquiti [...]
E2f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099434Transcription factor E2F1; Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of gen [...]
Rpl23 protein networkhttps://string-db.org/network/10090.ENSMUSP0000009943560S ribosomal protein L23.
Psmb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099436Proteasome subunit beta type-3; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles wi [...]
Cdk5rap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099441CDK5 regulatory subunit-associated protein 3; Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell proliferation. Negatively regulates NF- kappa-B-mediated gene [...]
Skap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099443Src kinase-associated phosphoprotein 1; Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway (By similarity). Required for optimal conjugation between T-cells and an [...]
Ttll9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099444Probable tubulin polyglutamylase TTLL9; Probable tubulin polyglutamylase that forms polyglutamate side chains on tubulin. Acts when complexed with other proteins (Probable). By mediating tubulin [...]
Gip protein networkhttps://string-db.org/network/10090.ENSMUSP00000099446Gastric inhibitory polypeptide; Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion; Belongs to the glucagon family.
Sgca protein networkhttps://string-db.org/network/10090.ENSMUSP00000099451Alpha-sarcoglycan; Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Acsf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099453Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-ch [...]
Dstn protein networkhttps://string-db.org/network/10090.ENSMUSP00000099461Destrin; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner; Belongs to the actin-binding proteins ADF family.
Tnfrsf18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099462Tumor necrosis factor receptor superfamily member 18; Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-c [...]
Mib2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099465E3 ubiquitin-protein ligase MIB2; E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notc [...]
Lpo protein networkhttps://string-db.org/network/10090.ENSMUSP00000099466Lactoperoxidase.
Mtmr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099468Myotubularin-related protein 4; Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para- nitrophenylphosphate. Phosphorylates ph [...]
Pex10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099469Peroxisome biogenesis factor 10; Somewhat implicated in the biogenesis of peroxisomes.
Cds2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099470Phosphatidate cytidylyltransferase 2; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin; Belongs to the CDS fami [...]
Adra1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000099473Alpha-1D adrenergic receptor; This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.
Cltc protein networkhttps://string-db.org/network/10090.ENSMUSP00000099475Clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma me [...]
Itpa protein networkhttps://string-db.org/network/10090.ENSMUSP00000099482Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hyd [...]
Car4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099483Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity).
Znhit3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099484Zinc finger HIT domain-containing protein 3.
Nop56 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099487Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the [...]
Snrpb protein networkhttps://string-db.org/network/10090.ENSMUSP00000099488Small nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the sp [...]
Acaca protein networkhttps://string-db.org/network/10090.ENSMUSP00000099490Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps r [...]
Per3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099493Period circadian protein homolog 3; Originally described as a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processe [...]
Polr1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000099494DNA-directed RNA polymerase I subunit RPA2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core [...]
Ube4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000099501Ubiquitin conjugation factor E4 B; Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the [...]
Nle1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099502Notchless protein homolog 1; Plays a role in regulating Notch activity (Probable). Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its eff [...]
Pex14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099506Peroxisomal membrane protein PEX14; Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic [...]
Snrnp200 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099509U5 small nuclear ribonucleoprotein 200 kDa helicase; Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Involved in spliceosome [...]
Mtor protein networkhttps://string-db.org/network/10090.ENSMUSP00000099510Serine/threonine-protein kinase mTOR; Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, [...]
Spaca3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099512Sperm acrosome membrane-associated protein 3, processed form; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. It could [...]
Trpm7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099513Transient receptor potential cation channel subfamily M member 7; Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a cent [...]
Cdk5r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099514Cyclin-dependent kinase 5 activator 1, p25; p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine [...]
5730455P16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000099515Protein Njmu-R1; May have a role in spermatogenesis.
Nppa protein networkhttps://string-db.org/network/10090.ENSMUSP00000099520Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoti [...]
Nppb protein networkhttps://string-db.org/network/10090.ENSMUSP00000099521Brain natriuretic peptide; Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, v [...]
2510039O18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000099522Uncharacterized protein KIAA2013.
Fbn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099524Fibrillin-1; [Fibrillin-1]: Structural component of the 10-12 nm diameter microfibrils of the extracellular matrix, which conveys both structural and regulatory properties to load-bearing connect [...]
Sema6d protein networkhttps://string-db.org/network/10090.ENSMUSP00000099529Semaphorin-6D; Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other ne [...]
Tmem97 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099532Sigma intracellular receptor 2; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is [...]
B2m protein networkhttps://string-db.org/network/10090.ENSMUSP00000099534Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin f [...]
Cela2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000099539Chymotrypsin-like elastase family member 2A; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily.
Rpl23a protein networkhttps://string-db.org/network/10090.ENSMUSP0000009954160S ribosomal protein L23a; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA (By similar [...]
Hspb7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099544Heat shock protein beta-7.
Szrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099545SUZ domain-containing protein 1.
Epb42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099548Erythrocyte membrane protein band 4.2; Probably plays an important role in the regulation of erythrocyte shape and mechanical properties; Belongs to the transglutaminase superfamily. Transglutami [...]
Crocc protein networkhttps://string-db.org/network/10090.ENSMUSP00000099549Rootletin; Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends prox [...]
Coro6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099551Coronin-6.
Nsrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099552Nuclear speckle splicing regulatory protein 1; RNA-binding protein that mediates pre-mRNA alternative splicing regulation; Belongs to the NSRP1 family.
Tmigd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099553Transmembrane and immunoglobulin domain-containing protein 1; May control cell-cell adhesion, cell migration and proliferation, cell morphology, and protects renal epithelial cells from oxidative [...]
Lrrc57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099555Leucine-rich repeat-containing protein 57.
Gemin4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099558Gem (Nuclear organelle) associated protein 4.
Vps39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099559Vam6/Vps39-like protein; May play a role in clustering and fusion of late endosomes and lysosomes (By similarity). Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2- [...]
Mrto4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099561mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolu [...]
Pla2g5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099571Calcium-dependent phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. This isozyme hydrolyzes L-alpha- palmitoyl-2-oleoyl phosphatidyl [...]
Rtn4rl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099572Reticulon-4 receptor-like 1; Cell surface receptor that plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. [...]
Dll4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099575Delta-like protein 4; Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migra [...]
Ece1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099576Endothelin-converting enzyme 1; Converts big endothelin-1 to endothelin-1.
Chst14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099579Carbohydrate sulfotransferase 14; Catalyzes the transfer of sulfate to position 4 of the N- acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0- [...]
Rap1gap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099580Rap1 GTPase-activating protein 2; GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP- bound state.
Cela3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000099581Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity; Belongs to the peptidase S1 family. Elastase subfamily.
Plcb2 protein networkhttps://string-db.org/network/10090.ENSMUSP000000995831-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activ [...]
Arpc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099584Actin-related protein 2/3 complex subunit 3; Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The [...]
Trpv1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099585Transient receptor potential cation channel subfamily V member 1; Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. See [...]
Ppp1cc protein networkhttps://string-db.org/network/10090.ENSMUSP00000099587Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate h [...]
Sema3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000099589Semaphorin-3B; Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
Tcea3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099592Transcription elongation factor A protein 3; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property [...]
Rasgrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099593RAS guanyl-releasing protein 1; Functions as a calcium- and diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. Activa [...]
Rpl11 protein networkhttps://string-db.org/network/10090.ENSMUSP0000009959560S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RN [...]
Gale protein networkhttps://string-db.org/network/10090.ENSMUSP00000099599UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine t [...]
Dph6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099601Diphthine--ammonia ligase; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP. Diphthamide biosynthesis consists in the conversion of an L-histidine residue i [...]
Arhgap11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000099604Rho GTPase-activating protein 11A.
Il22ra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099605Interleukin-22 receptor subunit alpha-1; Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. [...]
Fmn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099606Formin-1; Plays a role in the formation of adherens junction and the polymerization of linear actin cables.
Mtfr1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000099609Mitochondrial fission regulator 1-like.
Hmgn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099613High mobility group nucleosomal binding domain 2.
Kif1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000099614Kinesin-like protein KIF1C; Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility (By similarity).
Dnajc24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099615DnaJ homolog subfamily C member 24; The iron-bound form is redox-active and can function as electron carrier (By similarity). Stimulates the ATPase activity of several Hsp70-type chaperones. This [...]
Chrne protein networkhttps://string-db.org/network/10090.ENSMUSP00000099616Acetylcholine receptor subunit epsilon; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting c [...]
Rpa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099621Replication protein A 32 kDa subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replicat [...]
Med18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099627Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Phactr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099628Phosphatase and actin regulator 4; Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. [...]
Asgr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099632Asialoglycoprotein receptor 2; Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor rec [...]
Trim44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099633Tripartite motif-containing protein 44; May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17 (By similarity). Is [...]
Acadvl protein networkhttps://string-db.org/network/10090.ENSMUSP00000099634Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, myristoyl-CoA and stearoyl-CoA. Can accom [...]
Matn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099636Cartilage matrix protein; Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage. It binds to collagen.
Ankrd13a protein networkhttps://string-db.org/network/10090.ENSMUSP00000099638Ankyrin repeat domain-containing protein 13A; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regul [...]
Acacb protein networkhttps://string-db.org/network/10090.ENSMUSP00000099642Acetyl-CoA carboxylase 2; Mitochondrial enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA and plays a central role in fatty acid metabolism (By similarity). Catalyzes a 2 steps [...]
Fgf11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099645Fibroblast growth factor 11; Probably involved in nervous system development and function.
Tmem39b protein networkhttps://string-db.org/network/10090.ENSMUSP00000099648Transmembrane protein 39B.
Kpna6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099650Importin subunit alpha-7; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or biparti [...]
Tmem234 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099651Transmembrane protein 234.
Tjp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099652Tight junction protein ZO-1; Tjp1, TjpP2, and Tjp3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, a [...]
Eif3i protein networkhttps://string-db.org/network/10090.ENSMUSP00000099653Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein [...]
1110051M20Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000099654UPF0705 protein C11orf49 homolog.
Hdac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099657Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic rep [...]
Rbbp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099658Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a mann [...]
Sync protein networkhttps://string-db.org/network/10090.ENSMUSP00000099659Syncoilin; Atypical type III intermediate filament (IF) protein that may play a supportive role in the efficient coupling of mechanical stress between the myofibril and fiber exterior. May facili [...]
Fndc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099660Fibronectin type III domain-containing protein 5; [Irisin]: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in [...]
Trappc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099661Trafficking protein particle complex subunit 1; May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Slc25a35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099666Solute carrier family 25 member 35.
AU040320 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099667Dyslexia-associated protein KIAA0319-like protein; Possible role in axon guidance through interaction with RTN4R.
Myh10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099671Myosin-10; Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts for [...]
Tekt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099676Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. [...]
Adprhl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099677ADP-ribose glycohydrolase ARH3; ADP-ribose glycohydrolase that preferentially hydrolyzes the scissile alpha-O-linkage attached to the anomeric C1'' position of ADP- ribose and acts on different s [...]
Fndc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099680Fibronectin type III domain-containing protein 7.
Stxbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099681Syntaxin-binding protein 3; Together with STX4 and VAMP2, may play a role in insulin- dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell su [...]
Olfr1158 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099682Olfactory receptor.
Olfr1128 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099684Olfactory receptor Olfr1128.
Sars protein networkhttps://string-db.org/network/10090.ENSMUSP00000099685Serine--tRNA ligase, cytoplasmic; Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end [...]
Yrdc protein networkhttps://string-db.org/network/10090.ENSMUSP00000099688YrdC domain-containing protein, mitochondrial; May regulate the activity of some transporters.
Psrc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099689Proline/serine-rich coiled-coil protein 1; Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal [...]
Atxn7l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099693Ataxin 7-like 2.
Akirin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099696Akirin-1; Functions as signal transducer for MSTN during skeletal muscle regeneration and myogenesis. May regulate chemotaxis of both macrophages and myoblasts by reorganising actin cytoskeleton, [...]
Oxct2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000099700Succinyl-CoA:3-ketoacid coenzyme A transferase 2A, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA inter [...]
Ube2l6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099702Ubiquitin/ISG15-conjugating enzyme E2 L6; Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquit [...]
Med19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099705Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Selenoh protein networkhttps://string-db.org/network/10090.ENSMUSP00000099706Selenoprotein H; May be involved in a redox-related process.
Oxct2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000099708Succinyl-CoA:3-ketoacid coenzyme A transferase 2B, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA inter [...]
Trit1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099709tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethyla [...]
Akap10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099710A-kinase anchor protein 10, mitochondrial; Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma m [...]
Pde1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000099715Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regul [...]
Foxo6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099716Forkhead box protein O6; Transcriptional activator.
B9d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099717B9 domain-containing protein 1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembran [...]
Itga4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099718Integrin alpha-4; Integrins alpha-4/beta-1 (VLA-4 or LPAM-2) and alpha-4/beta-7 (LPAM-1) are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 an [...]
Sestd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099721SEC14 domain and spectrin repeat-containing protein 1; May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5 [...]
P3h1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099723Prolyl 3-hydroxylase 1; Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post- translational formation of 3-hydroxyproline in [...]
Mog protein networkhttps://string-db.org/network/10090.ENSMUSP00000099726Myelin-oligodendrocyte glycoprotein; Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophili [...]
Nfe2l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099733Nuclear factor erythroid 2-related factor 2; Transcription factor that plays a key role in the response to oxidative stress: binds to antioxidant response (ARE) elements present in the promoter r [...]
H2-T3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099736H-2 class I histocompatibility antigen, TLA(B) alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family.
H2-T23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099739H-2 class I histocompatibility antigen, D-37 alpha chain; Involved in the presentation of foreign antigens to the immune system.
Tom1l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099744TOM1-like protein 2; Probable role in protein transport. May regulate growth factor-induced mitogenic signaling (By similarity); Belongs to the TOM1 family.
Dmap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099748DNA methyltransferase 1-associated protein 1; Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin [...]
Sp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099750Transcription factor Sp3; Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements [...]
Cdca7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099752Cell division cycle-associated protein 7; Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insuffici [...]
Pemt protein networkhttps://string-db.org/network/10090.ENSMUSP00000099754Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidyleth [...]
Ptgfrn protein networkhttps://string-db.org/network/10090.ENSMUSP00000099755Prostaglandin F2 receptor negative regulator; Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity c [...]
Nt5m protein networkhttps://string-db.org/network/10090.ENSMUSP000000997565'(3')-deoxyribonucleotidase, mitochondrial; Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication f [...]
Rps8 protein networkhttps://string-db.org/network/10090.ENSMUSP0000009975740S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family.
Flcn protein networkhttps://string-db.org/network/10090.ENSMUSP00000099758Folliculin; May be a tumor suppressor. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1; Belongs to the foll [...]
Mutyh protein networkhttps://string-db.org/network/10090.ENSMUSP00000099760Adenine DNA glycosylase; Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adeni [...]
Zfp39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099764Zinc finger protein 39; A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis.
Rad54l protein networkhttps://string-db.org/network/10090.ENSMUSP00000099765DNA repair and recombination protein RAD54-like; Involved in DNA repair and mitotic recombination. Functions in the recombinational DNA repair (RAD52) pathway. Dissociates RAD51 from nucleoprotei [...]
Cyp4b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099768Cytochrome P450 4B1; Responsible for mutagenic activation of 3-methoxy-4- aminoazobenzene (3-MeO-AAB); a potent procarcinogen. Also active on 2- aminofluorene and 2-aminoanthracene; Belongs to th [...]
Abcb11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099770Bile salt export pump; Catalyzes the secretion of conjugated bile salts across the canalicular membrane of hepatocytes in an ATP-dependent manner. Transports taurine-conjugated bile salts more ra [...]
4933409G03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000099774RIKEN cDNA 4933409G03 gene.
Stk39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099776STE20/SPS1-related proline-alanine-rich protein kinase; May act as a mediator of stress-activated signals. Mediates the inhibition of SLC4A4, SLC26A6 as well as CFTR activities by the WNK scaffol [...]
Ttc21b protein networkhttps://string-db.org/network/10090.ENSMUSP00000099779Tetratricopeptide repeat protein 21B; Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPCRs). Ess [...]
Slc5a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099782Sodium/glucose cotransporter 4; Involved in sodium-dependent transport of D-mannose, D- glucose and D-fructose; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Faf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099785FAS-associated factor 1; Ubiquitin-binding protein (By similarity). Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation (By si [...]
4930522H14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000099786Uncharacterized protein C1orf185 homolog.
Cobll1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099787Cordon-bleu protein-like 1.
Eps15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099790Epidermal growth factor receptor substrate 15; Involved in cell growth regulation. May be involved in the regulation of mitogenic signals and control of cell proliferation. Involved in the intern [...]
Tnip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099792TNFAIP3-interacting protein 1; Inhibits NF-kappa-B activation and TNF-induced NF-kappa-B- dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link [...]
Fap protein networkhttps://string-db.org/network/10090.ENSMUSP00000099793Antiplasmin-cleaving enzyme FAP, soluble form; Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including ti [...]
Gcg protein networkhttps://string-db.org/network/10090.ENSMUSP00000099794Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulator [...]
Kti12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099799Protein KTI12 homolog; Belongs to the KTI12 family.
Btf3l4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099803Transcription factor BTF3 homolog 4; Belongs to the NAC-beta family.
Orc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099805Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define ori [...]
Tnfaip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099806Tumor necrosis factor alpha-induced protein 2; May play a role as a mediator of inflammation and angiogenesis; Belongs to the SEC6 family.
Uba2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099807SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of [...]
March7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099809E3 ubiquitin-protein ligase MARCHF7; E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enz [...]
Arnt protein networkhttps://string-db.org/network/10090.ENSMUSP00000099810Aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the n [...]
Pkp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099815Plakophilin-4; Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques (By similarity). Belongs to the beta-catenin family.
Vdac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099819Voltage-dependent anion-selective channel protein 1; Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows [...]
Stam2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099820Signal transducing adapter molecule 2; Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leadi [...]
Cdkn2aipnl protein networkhttps://string-db.org/network/10090.ENSMUSP00000099824CDKN2AIP N-terminal-like protein.
Col23a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099826Collagen alpha-1(XXIII) chain.
Rbm43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099829RNA-binding protein 43.
Mmadhc protein networkhttps://string-db.org/network/10090.ENSMUSP00000099830Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial; Involved in cobalamin metabolism. Plays a role in regulating the biosynthesis of two coenzymes, methylcobalamin and adenos [...]
Ltc4s protein networkhttps://string-db.org/network/10090.ENSMUSP00000099833Leukotriene C4 synthase; Catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4.
Sqstm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099835Sequestosome-1; Autophagy receptor required for selective macroautophagy (aggrephagy). Functions as a bridge between polyubiquitinated cargo and autophagosomes. Interacts directly with both the c [...]
Rnf130 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099837E3 ubiquitin-protein ligase RNF130; Acts as an E3 ubiquitin-protein ligase (By similarity). May have a role during the programmed cell death of hematopoietic cells.
Jak1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099842Tyrosine-protein kinase JAK1; Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleu [...]
Gm2000 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099843Predicted gene 2000.
Dennd1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000099848DENN domain-containing protein 1A; Guanine nucleotide exchange factor (GEF) regulating clathrin- mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting ina [...]
Kank4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099851KN motif and ankyrin repeat domain-containing protein 4; May be involved in the control of cytoskeleton formation by regulating actin polymerization.
Cd47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099853Leukocyte surface antigen CD47; Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory fo [...]
Tm2d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099855TM2 domain-containing protein 1; May participate in amyloid-beta-induced apoptosis via its interaction with beta-APP42.
Ebf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099857Transcription factor COE1; Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Belongs to the COE family.
Ggta1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099858N-acetyllactosaminide alpha-1,3-galactosyltransferase; Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on termin [...]
Ublcp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099859Ubiquitin-like domain-containing CTD phosphatase 1; Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core [...]
Tek protein networkhttps://string-db.org/network/10090.ENSMUSP00000099862Angiopoietin-1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, [...]
Gapvd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099864GTPase-activating protein and VPS9 domain-containing protein 1; Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in various processe [...]
Tenm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099865Ten-2 intracellular domain; Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Acts as a ligand of the ADGRL1 receptor. Promotes the fo [...]
Ifna5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099868Interferon alpha-5; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs t [...]
Cd200r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099869Cell surface glycoprotein CD200 receptor 2; According to it is a receptor for the CD200 cell surface glycoprotein. According to it is not a receptor for the CD200/OX2 cell surface glycoprotein. I [...]
Ifna12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099870Interferon alpha-12; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase (By simil [...]
Ifna9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099871Interferon alpha-9; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs t [...]
Ifna14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099872Interferon, alpha 14.
Ifna15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099873Predicted gene, OTTMUSG00000007655.
Garnl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099874GTPase-activating Rap/Ran-GAP domain-like protein 3.
Cfap157 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099877Cilia- and flagella-associated protein 157; Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility. May be required to suppress the formation of supernumerary [...]
Rps6 protein networkhttps://string-db.org/network/10090.ENSMUSP0000009987840S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.
Ranbp17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099879Ran-binding protein 17; May function as a nuclear transport receptor; Belongs to the exportin family.
Gap43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099881Neuromodulin; This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filop [...]
St6galnac4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099882N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7D); Involved in the biosynthesis of ganglioside GD1A from GM1B. Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc res [...]
Stk10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099885Serine/threonine-protein kinase 10; Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte mig [...]
Ttc39b protein networkhttps://string-db.org/network/10090.ENSMUSP00000099887Tetratricopeptide repeat protein 39B; Regulates high density lipoprotein (HDL) cholesterol metabolism by promoting the ubiquitination and degradation of the oxysterols receptors LXR (NR1H2 and NR [...]
Ifit1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099888Interferon-induced protein with tetratricopeptide repeats 1; Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA) [...]
Ifit3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099889Interferon-induced protein with tetratricopeptide repeats 3; IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signal [...]
Ifit2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099890Interferon-induced protein with tetratricopeptide repeats 2; IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'- [...]
Icos protein networkhttps://string-db.org/network/10090.ENSMUSP00000099891Inducible T-cell costimulator; Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interact [...]
4930524B15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000099893Uncharacterized protein C5orf47 homolog.
Mpdz protein networkhttps://string-db.org/network/10090.ENSMUSP00000099894Multiple PDZ domain protein; Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and [...]
Cd3e protein networkhttps://string-db.org/network/10090.ENSMUSP00000099896T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting c [...]
Ass1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099904Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic [...]
Rtn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099907Reticulon-4; Required to induce the formation and stabilization of endoplasmic reticulum (ER) tubules. They regulate membrane morphogenesis in the ER by promoting tubular ER production. They infl [...]
Rps27a protein networkhttps://string-db.org/network/10090.ENSMUSP00000099909Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an is [...]
Usp20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099913Ubiquitin carboxyl-terminal hydrolase 20; Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by m [...]
Ptges protein networkhttps://string-db.org/network/10090.ENSMUSP00000099916Prostaglandin E synthase; Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).
Cstad protein networkhttps://string-db.org/network/10090.ENSMUSP00000099917CSA-conditional, T cell activation-dependent protein.
Crat protein networkhttps://string-db.org/network/10090.ENSMUSP00000099919Carnitine O-acetyltransferase; Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport [...]
Tex48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099925Testis-expressed 48.
Rel protein networkhttps://string-db.org/network/10090.ENSMUSP00000099928Proto-oncogene c-Rel; Proto-oncogene that may play a role in differentiation and lymphopoiesis. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is i [...]
Set protein networkhttps://string-db.org/network/10090.ENSMUSP00000099930Protein SET; Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone chaperoning. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activ [...]
Xpo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099933Exportin-1; Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperative [...]
L1cam protein networkhttps://string-db.org/network/10090.ENSMUSP00000099935Neural cell adhesion molecule L1; Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain [...]
Mdh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099938Malate dehydrogenase, cytoplasmic.
Ugp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099939UTP--glucose-1-phosphate uridylyltransferase; Plays a central role as a glucosyl donor in cellular metabolic pathways.
Ppp3r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099944Calcineurin subunit B type 1; Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
Plek protein networkhttps://string-db.org/network/10090.ENSMUSP00000099945Pleckstrin; Major protein kinase C substrate of platelets.
Ptbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099947Polypyrimidine tract-binding protein 3; RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migra [...]
Sardh protein networkhttps://string-db.org/network/10090.ENSMUSP00000099950Sarcosine dehydrogenase, mitochondrial; Belongs to the GcvT family.
Camk2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000099952Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, [...]
Ecpas protein networkhttps://string-db.org/network/10090.ENSMUSP00000099953Proteasome adapter and scaffold protein ECM29; Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment specific proteins. May couple the proteasome to d [...]
Adamts13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099955A disintegrin and metalloproteinase with thrombospondin motifs 13; Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation.
Lilr4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000099958Mast cell surface glycoprotein Gp49A; May play a role in cell-cell or cell-cytokine interactions during the development of mast cells.
Txndc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099961Thioredoxin domain-containing protein 8; May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm ( [...]
Rpl7a protein networkhttps://string-db.org/network/10090.ENSMUSP0000009996260S ribosomal protein L7a.
Abo protein networkhttps://string-db.org/network/10090.ENSMUSP00000099964Histo-blood group ABO system transferase.
Pakap-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099969Paralemmin-2.
Wap protein networkhttps://string-db.org/network/10090.ENSMUSP00000099974Whey acidic protein; Could be a protease inhibitor. May play an important role in mammary gland development and tissue remodeling.
Slc44a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099975Choline transporter-like protein 1; Choline transporter. May be involved in membrane synthesis and myelin production; Belongs to the CTL (choline transporter-like) family.
March3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099976E3 ubiquitin-protein ligase MARCHF3; E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in t [...]
Smc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099979Structural maintenance of chromosomes protein 2; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The [...]
Col15a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099981Collagen alpha-1(XV) chain; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle; Belongs to the multiplexin collagen family.
Abca2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099983ATP-binding cassette sub-family A member 2; Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development; Belongs to t [...]
Gck protein networkhttps://string-db.org/network/10090.ENSMUSP00000099984Hexokinase-4; Catalyzes the phosphorylation of hexose, such as D-glucose, D-fructose and D-mannose, to hexose 6-phosphate (D-glucose 6-phosphate, D-fructose 6-phosphate and D-mannose 6-phosphate, [...]
Myl7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099985Myosin regulatory light chain 2, atrial isoform.
Pold2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099986DNA polymerase delta subunit 2; Accessory component of both the DNA polymerase delta complex and the DNA polymerase zeta complex. As a component of the trimeric and tetrameric DNA polymerase delt [...]
Aebp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099987Adipocyte enhancer-binding protein 1; [Isoform 1]: As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix; Bel [...]
Uap1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000099989UDP-N-acetylhexosamine pyrophosphorylase-like protein 1.
Anp32b protein networkhttps://string-db.org/network/10090.ENSMUSP00000099990Acidic leucine-rich nuclear phosphoprotein 32 family member B; Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression f [...]
Pdpk1 protein networkhttps://string-db.org/network/10090.ENSMUSP000000999913-phosphoinositide-dependent protein kinase 1; Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets i [...]
Psd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100006PH and SEC7 domain-containing protein 4; Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II- containing vesicles along the [...]
Hus1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000100007Checkpoint protein HUS1B.
Creb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100008Processed cyclic AMP-responsive element-binding protein 3; Endoplasmic reticulum (ER)-bound sequence-specific transcription factor that directly binds DNA and activates transcription. Plays a rol [...]
Nxph2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100009Neurexophilin-2; May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors. Belongs to the neurexophilin family.
Exoc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100010Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
E2f3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100012Transcription factor E2F3; Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of gen [...]
Sox4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100013Transcription factor SOX-4; Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.
Prl2b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100019Prolactin-2B1; Belongs to the somatotropin/prolactin family.
Cetn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100020Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis.
Ccl19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100022C-C motif chemokine 19; Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a r [...]
Stam protein networkhttps://string-db.org/network/10090.ENSMUSP00000100025Signal transducing adapter molecule 1; Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leadi [...]
Cntfr protein networkhttps://string-db.org/network/10090.ENSMUSP00000100026Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity); Belongs to the type I cytokine receptor family. Type 3 subf [...]
Dnaic1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100028Dynein intermediate chain 1, axonemal; Part of the dynein complex of respiratory cilia.
H4c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100029H4 clustered histone 1.
H4c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100030H4 clustered histone 2.
H4c3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100032H4 clustered histone 3.
H4c4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100033H4 clustered histone 4.
H2ac8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100034H2A clustered histone 8.
H4c6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100036H4 clustered histone 6.
H4c8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100037H4 clustered histone 8.
Aco1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100038Cytoplasmic aconitate hydratase; Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, seques [...]
Mob3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000100040MOB kinase activator 3B; Modulates LATS1 expression in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promotin [...]
Gata3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100041Trans-acting T-cell-specific transcription factor GATA-3; Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AG [...]
H4c9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100042H4 clustered histone 9.
Zfp184 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100043Zinc finger protein 184; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Hist1h4n protein networkhttps://string-db.org/network/10090.ENSMUSP00000100044Histone cluster 1, H4n.
Akr1b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100045Aldo-keto reductase family 1 member B1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity tow [...]
Sec61a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100046Protein transport protein Sec61 subunit alpha isoform 2; Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membran [...]
H4c12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100048H4 clustered histone 12.
Mcm10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100050Protein MCM10 homolog; Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Addition [...]
Dclre1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000100053Protein artemis; Required for V(D)J recombination, the process by which exons encoding the antigen-binding domains of immunoglobulins and T-cell receptor proteins are assembled from individual V, [...]
Ube2h protein networkhttps://string-db.org/network/10090.ENSMUSP00000100058Ubiquitin-conjugating enzyme E2 H; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. E2 ubiquitin conjugating enzyme that transfers ubiquitin to MAEA, [...]
Ufl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100059E3 UFM1-protein ligase 1; E3 protein ligase that mediates ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, a post-translational modification on lysin [...]
4930452B06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000100061Uncharacterized protein C3orf67 homolog.
Ccnc protein networkhttps://string-db.org/network/10090.ENSMUSP00000100062Cyclin-C; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey infor [...]
Cngb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100064Cyclic nucleotide-gated cation channel beta-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which le [...]
Ssx9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100066Synovial sarcoma, X 9.
Ssxb10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100068Synovial sarcoma, X member B10.
Shroom4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100070Protein Shroom4; Probable regulator of cytoskeletal architecture that plays an important role in development. May regulate cellular and cytoskeletal architecture by modulating the spatial distrib [...]
Nudt10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100071Diphosphoinositol polyphosphate phosphohydrolase 3-alpha; Cleaves a beta-phosphate from the diphosphate groups in PP- InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a ro [...]
Nudt11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100072Nudix (nucleoside diphosphate linked moiety X)-type motif 11.
Iglc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100464Ig lambda-2 chain C region.
Olfr26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100467Olfactory receptor.
Olfr585 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100476Olfactory receptor.
Ranbp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100503Ran-binding protein 6; May function in nuclear protein import as nuclear transport receptor; Belongs to the importin beta family.
Zxdb protein networkhttps://string-db.org/network/10090.ENSMUSP00000100524Zinc finger X-linked protein ZXDB; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
Fam170b protein networkhttps://string-db.org/network/10090.ENSMUSP00000100529Protein FAM170B; Plays a role in fertilization through the acrosome reaction. Belongs to the FAM170 family.
Actl10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100532Actin-like protein 10; Belongs to the actin family.
Gm11555 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100533Predicted gene 11555.
Mcts2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100534Malignant T-cell-amplified sequence 2.
Krtap1-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100535Keratin-associated protein 1-3.
Gm11939 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100536Predicted gene 11939.
Mageb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100541Melanoma antigen, family B, 3.
Ankrd63 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100542Ankyrin repeat domain-containing protein 63.
Hist1h4m protein networkhttps://string-db.org/network/10090.ENSMUSP00000100546Histone cluster 1, H4m.
AK157302 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100547cDNA sequence AK157302.
Capns2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100553Calpain small subunit 2; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small s [...]
Sowaha protein networkhttps://string-db.org/network/10090.ENSMUSP00000100561Ankyrin repeat domain-containing protein SOWAHA; Belongs to the SOWAH family.
Psme2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000100564Proteasome activator complex subunit 2; Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I bindin [...]
Gm12184 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100565Predicted gene 12184.
Fem1al protein networkhttps://string-db.org/network/10090.ENSMUSP00000100568Protein fem-1 homolog A-B; Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via [...]
Igkv4-71 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100575Ig kappa chain V-VI region NQ2-17.4.1; Anti-2-phenyl oxazolone (PHOX) Antibody.
Ubl4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000100577Ubiquitin-like protein 4B.
H2ac19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100581H2A clustered histone 19.
Tmem139 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100590Transmembrane protein 139.
Rnf148 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100592RING finger protein 148.
Psapl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100594Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids.
Papolb protein networkhttps://string-db.org/network/10090.ENSMUSP00000100595Poly(A) polymerase beta.
Rbm8a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100599RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
Chml protein networkhttps://string-db.org/network/10090.ENSMUSP00000100600Rab proteins geranylgeranyltransferase component A 2; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents t [...]
Tmem203 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100614Transmembrane protein 203; Involved in the regulation of cellular calcium homeotasis. Required for spermatogenesis.
Nrarp protein networkhttps://string-db.org/network/10090.ENSMUSP00000100615Notch-regulated ankyrin repeat-containing protein; Downstream effector of Notch signaling. Involved in the regulation of liver cancer cells self-renewal (By similarity). Involved in the regulatio [...]
Otud1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100617OTU domain-containing protein 1; Deubiquitinating enzyme that specifically hydrolyzes 'Lys- 63'-linked polyubiquitin to monoubiquitin.
H2al2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000100618Histone H2A-Bbd type 1; Atypical histone H2A which replaces conventional H2A during late spermatogenesis and is involved in the replacement of histones to protamine in male germ cells. Core compo [...]
Fthl17d protein networkhttps://string-db.org/network/10090.ENSMUSP00000100621Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Btbd35f7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100624BTB domain-containing 35, family member 7.
Btbd35f21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100634BTB domain-containing 35, family member 21.
Btbd35f18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100636BTB domain-containing 35, family member 18.
Btbd35f11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100637BTB domain-containing 35, family member 11.
Klhdc7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000100648Kelch domain-containing protein 7A.
Fam43b protein networkhttps://string-db.org/network/10090.ENSMUSP00000100649Family with sequence similarity 43, member B.
Gm3550 protein networkhttps://string-db.org/network/10090.ENSMUSP0000010065560S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family.
Sft2d3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100656Vesicle transport protein SFT2C; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.
Hmga1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000100667High mobility group protein HMG-I/HMG-Y; HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleoso [...]
Krtap17-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100670Keratin-associated protein 17-1.
Krtap16-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100671Keratin-associated protein 16-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Krtap29-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100672Keratin-associated protein 29-1; Belongs to the KRTAP type 10 family.
Krtap9-5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100673Keratin-associated protein 9-5.
Gm11565 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100674Predicted gene 11565.
2300003K06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000100675RIKEN cDNA 2300003K06 gene.
Gm11564 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100676Predicted gene 11564.
Gm11554 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100677Predicted gene 11554.
Gm11569 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100678Predicted gene 11569.
Gm11596 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100679Predicted gene 11596.
Krtap4-9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100680Keratin associated protein 4-9.
Tas2r122 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100699Taste receptor type 2.
Dnajb7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100712DnaJ homolog subfamily B member 7; Probably acts as a co-chaperone.
Foxd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100725Forkhead box protein D1; Transcription factor involved in regulation of gene expression in a variety of processes including formation of positional identity in the developing retina, regionalizat [...]
H3c4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100737H3 clustered histone 4.
H2bc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100738H2B clustered histone 7.
H3c6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100739H3 clustered histone 6.
F8a protein networkhttps://string-db.org/network/10090.ENSMUSP0000010074340-kDa huntingtin-associated protein; RAB5A effector molecule that is involved in vesicular trafficking of early endosomes. Mediates the recruitment of HTT by RAB5A onto early endosomes (By simil [...]
Tex13c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100745Testis-expressed protein 13C-1; Belongs to the TEX13 family.
Btbd35f14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100749BTB domain-containing 35, family member 14.
Gm21637 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100756Predicted gene, 21637.
H2al1n protein networkhttps://string-db.org/network/10090.ENSMUSP00000100769Histone H2A; Belongs to the histone H2A family.
Sf3b5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100771Splicing factor 3B subunit 5; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly [...]
Ifna7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100774Interferon alpha-7.
Ifnz protein networkhttps://string-db.org/network/10090.ENSMUSP00000100775Interferon zeta.
Ifna6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100777Interferon alpha-6; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Ifna2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100778Interferon alpha-2; Produced by macrophages, IFN-alpha have antiviral activities.
Ifna16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100779Interferon alpha 16.
Ifna13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100780Interferon alpha-13; Exhibits antiviral activity against Theiler's virus, Mengo virus and vesicular stomatitis virus. Interferons alpha stimulate the production of two enzymes: a protein kinase a [...]
Mos protein networkhttps://string-db.org/network/10090.ENSMUSP00000100789Proto-oncogene serine/threonine-protein kinase mos.
Vmn1r3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100790Vomeronasal type-1 receptor.
Rpl10l protein networkhttps://string-db.org/network/10090.ENSMUSP0000010079560S ribosomal protein L10-like; Belongs to the universal ribosomal protein uL16 family.
Vmn1r254 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100822Taste receptor type 2.
Vmn1r249 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100830Vomeronasal type-1 receptor.
Vmn1r248 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100831Taste receptor type 2.
Vmn1r244 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100844Vomeronasal 1 receptor 244.
Sarnp protein networkhttps://string-db.org/network/10090.ENSMUSP00000100863SAP domain-containing ribonucleoprotein; Binds both single-stranded and double-stranded DNA with higher affinity for the single-stranded form. Specifically binds to scaffold/matrix attachment reg [...]
Smarcc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100868SWI/SNF complex subunit SMARCC2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chroma [...]
Gpr182 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100882G-protein coupled receptor 182; Orphan receptor.
Ctdsp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100891Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain [...]
Cnot2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100902CCR4-NOT transcription complex subunit 2; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA de [...]
Osbpl8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100911Oxysterol-binding protein-related protein 8; Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylser [...]
Syt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100912Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic ves [...]
Kitl protein networkhttps://string-db.org/network/10090.ENSMUSP00000100920Soluble KIT ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, g [...]
Epyc protein networkhttps://string-db.org/network/10090.ENSMUSP00000100922Epiphycan; May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization.
Kera protein networkhttps://string-db.org/network/10090.ENSMUSP00000100923Keratocan; May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP clas [...]
Dcn protein networkhttps://string-db.org/network/10090.ENSMUSP00000100924Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
Nr2c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100927Nuclear receptor subfamily 2 group C member 1; Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor [...]
Nr1h4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100933Bile acid receptor; Ligand-activated transcription factor. Receptor for bile acids (BAs) such as chenodeoxycholic acid (CDCA), lithocholic acid, deoxycholic acid (DCA) and allocholic acid (ACA). [...]
Igf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100937Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be [...]
Btbd11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100944Ankyrin repeat and BTB/POZ domain-containing protein BTBD11.
Smim24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100959Small integral membrane protein 24.
Dot1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000100973Histone-lysine N-methyltransferase, H3 lysine-79 specific.
Tcf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100979Transcription factor E2-alpha; Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) prote [...]
Mex3d protein networkhttps://string-db.org/network/10090.ENSMUSP00000100987RNA-binding protein MEX3D; RNA binding protein, may be involved in post-transcriptional regulatory mechanisms.
Reep6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000100991Receptor expression-enhancing protein 6; Required for correct function and survival of retinal photoreceptors. Required for retinal development. In rod photoreceptors, facilitates stability and/o [...]
Ndufs7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101003NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the [...]
Cirbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000101004Cold-inducible RNA-binding protein; Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival [...]
Atp5d protein networkhttps://string-db.org/network/10090.ENSMUSP00000101006ATP synthase subunit delta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane [...]
Cbarp protein networkhttps://string-db.org/network/10090.ENSMUSP00000101008Voltage-dependent calcium channel beta subunit-associated regulatory protein; Negatively regulates voltage-gated calcium channels by preventing the interaction between their alpha and beta subuni [...]
Arhgap45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101012Rho GTPase-activating protein 45; Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. [...]
Ccdc105 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101022Coiled-coil domain-containing protein 105.
Ilvbl protein networkhttps://string-db.org/network/10090.ENSMUSP00000101023Acetolactate synthase-like protein; Belongs to the TPP enzyme family.
Icosl protein networkhttps://string-db.org/network/10090.ENSMUSP00000101032ICOS ligand; Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and diffe [...]
Cfap410 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101036Cilia- and flagella-associated protein 410; Plays a role in cilia formation and/or maintenance. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). In [...]
Trpm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101040Transient receptor potential cation channel subfamily M member 2; Nonselective, voltage-independent cation channel that mediates Na(+) and Ca(2+) influx, leading to increased cytoplasmic Ca(2+) l [...]
Adarb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101046Double-stranded RNA-specific editase 1; Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene express [...]
Col18a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101049Collagen alpha-1(XVIII) chain; Probably plays a major role in determining the retinal structure as well as in the closure of the neural tube. Endostatin: Potently inhibits endothelial cell proli [...]
Slc19a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101050Reduced folate transporter; Transporter that mediates the import of reduced folates. Has high affinity for N5-methyltetrahydrofolate, the predominant circulating form of folate. Also able to medi [...]
Adora2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000101060Adenosine receptor A2a; Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity).
Specc1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000101061Cytospin-A; Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migr [...]
Zwint protein networkhttps://string-db.org/network/10090.ENSMUSP00000101071ZW10 interactor; Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase (By similarity) [...]
Lrrtm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101079Leucine-rich repeat transmembrane neuronal protein 3; May play a role in the development and maintenance of the vertebrate nervous system. Exhibits a limited synaptogenic activity in vitro, restr [...]
Ctnna3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101080Catenin alpha-3; May be involved in formation of stretch-resistant cell-cell adhesion complexes.
Col13a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101094Collagen alpha-1(XIII) chain; Involved in cell-matrix and cell-cell adhesion interactions that are required for normal development. May participate in the linkage between muscle fiber and basemen [...]
Cdh23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101104Cadherin-23; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing an [...]
Slc35f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101113Solute carrier family 35 member F1; Putative solute transporter; Belongs to the SLC35F solute transporter family.
Prdm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101129PR domain zinc finger protein 1; Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident [...]
Foxo3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101141Forkhead box protein O3; Transcriptional activator that recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' and regulates different processes, such as apoptosis and autophagy. Acts as a [...]
Ppil6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101146Probable inactive peptidyl-prolyl cis-trans isomerase-like 6; Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
Wasf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101148Wiskott-Aldrich syndrome protein family member 1; Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. [...]
Col10a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101150Collagen alpha-1(X) chain; Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage.
Ahi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101164Jouberin; Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tec [...]
Phactr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101182Phosphatase and actin regulator.
Plekhn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101194Kelch-like protein 17; Substrate-recognition component of some cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(KLHL17) mediates the ubiquitination and subsequen [...]
Perm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101197PGC-1 and ERR-induced regulator in muscle protein 1; Regulates the expression of selective PPARGC1A/B and ESRRA/B/G target genes with roles in glucose and lipid metabolism, energy transfer, contr [...]
Acap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101209ArfGAP with coiled-coil, ankyrin repeat and PH domains 3.
Esr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101215Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differenti [...]
Gm10945 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101221Predicted gene 10945.
Cdk11b protein networkhttps://string-db.org/network/10090.ENSMUSP00000101225Cyclin-dependent kinase 11B; Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity- dependent manner. May act as a negative [...]
Slc35e2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101233Solute carrier family 35 member E2A; Putative transporter; Belongs to the TPT transporter family. SLC35E subfamily.
Oprm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101236Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, [...]
Nadk protein networkhttps://string-db.org/network/10090.ENSMUSP00000101238NAD kinase; Belongs to the NAD kinase family.
Plch2 protein networkhttps://string-db.org/network/10090.ENSMUSP000001012561-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activa [...]
Trp73 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101269Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block [...]
Ajap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101271Adherens junction-associated protein 1; Plays a role in cell adhesion and cell migration.
Gpr153 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101276Probable G-protein coupled receptor 153; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Plekhg5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101286Pleckstrin homology domain-containing family G member 5; Functions as a guanine exchange factor (GEF) for RAB26 and thus regulates autophagy of synaptic vesicles in axon terminal of motoneurons. [...]
Park7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101299Protein/nucleic acid deglycase DJ-1; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive ca [...]
Rere protein networkhttps://string-db.org/network/10090.ENSMUSP00000101307Arginine-glutamic acid dipeptide repeats protein; Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival.
Slc25a33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101311Solute carrier family 25 member 33; Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Transports preferentially uracil, thymine, and cytosine (deox [...]
Tmem201 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101312Transmembrane protein 201; Involved in nuclear movement during fibroblast polarization and migration. May recruit Ran GTPase to the nuclear periphery (By similarity). [Isoform 3]: Proposed to be [...]
Pik3cd protein networkhttps://string-db.org/network/10090.ENSMUSP00000101315Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to gener [...]
Nmnat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101318Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic aci [...]
Gm572 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101323Predicted gene 572.
Fbxo6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101331F-box only protein 6; Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complexes. Involved in DNA damage response by specifically recognizing activat [...]
Zfp933 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101343Zinc finger protein 933.
Zfp979 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101345Zinc finger protein 979.
Zfp982 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101346Zinc finger protein 982.
Zfp992 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101359Zinc finger protein 992.
Zfp984 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101360Zinc finger protein 984.
Zfp981 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101361Zinc finger protein 981.
Zfp980 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101364Zinc finger protein 980.
Gm13212 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101365Predicted gene 13212.
Zfp990 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101367Zinc finger protein 990.
Aadacl4fm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101372AADACL4 family member 5.
Aadacl4fm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101373AADACL4 family member 4.
Aadacl4fm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101374AADACL4 family member 2.
Aadacl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101375Arylacetamide deacetylase-like 3.
Gm13128 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101377Predicted gene 13128.
C87977 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101383Expressed sequence C87977.
Gm13102 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101387Predicted gene 13102.
Pramef17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101388PRAME family member 17.
Gm13101 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101389Predicted gene 13101.
BC080695 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101391cDNA sequence BC080695.
Pramef25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101392PRAME family member 25.
Gm13088 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101397Predicted gene 13088.
Gm13083 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101399Predicted gene 13083.
Gm13057 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101402Predicted gene 13040.
Prdm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101404PR domain-containing 2, with ZNF domain.
Fhad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101406Forkhead-associated domain-containing protein 1.
Rsc1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101408Regulatory solute carrier protein family 1 member 1; Mediates transcriptional and post-transcriptional regulation of SLC5A1. Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1. Als [...]
Spen protein networkhttps://string-db.org/network/10090.ENSMUSP00000101412Msx2-interacting protein; May serve as a nuclear matrix platform that organizes and integrates transcriptional responses. In osteoblasts, supports transcription activation: synergizes with RUNX2 [...]
Clcnka protein networkhttps://string-db.org/network/10090.ENSMUSP00000101416Chloride channel protein ClC-Ka; Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transdu [...]
Arhgef10l protein networkhttps://string-db.org/network/10090.ENSMUSP00000101425Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC.
Htr6 protein networkhttps://string-db.org/network/10090.ENSMUSP000001014285-hydroxytryptamine receptor 6; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that function as a neurotransmitter, a hormone, and a mitog [...]
Gm13030 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101431Predicted gene 13030.
Pla2g2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000101434Group IIC secretory phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Testis PA2 may be important in the production of prostaglandin [...]
Ubxn10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101436UBX domain-containing protein 10; VCP/p97-binding protein required for ciliogenesis. Acts as a tethering factor that facilitates recruitment of VCP/p97 to the intraflagellar transport complex B ( [...]
Sh2d5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101449SH2 domain-containing protein 5; May be involved in synaptic plasticity regulation through the control of Rac-GTP levels.
Rap1gap protein networkhttps://string-db.org/network/10090.ENSMUSP00000101461Rap1 GTPase-activating protein 1; GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP- bound state.
Kdm1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000101473Lysine-specific histone demethylase 1A; Histone demethylase that can demethylate both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depend [...]
Pithd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101477PITH domain-containing protein 1; Promotes megakaryocyte differentiation by up-regulating RUNX1 expression. Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by [...]
Srsf10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101479Serine/arginine-rich splicing factor 10; Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. Seems to interfere with the U1 snRNP 5'-splice recogni [...]
Myom3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101480Myomesin-3; May link the intermediate filament cytoskeleton to the M-disk of the myofibrils in striated muscle.
Grhl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101481Grainyhead-like protein 3 homolog; Transcription factor playing important roles in primary neurulation and in the differentiation of stratified epithelia of both ectodermal and endodermal origin. [...]
Nipal3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101482NIPA-like protein 3.
Ncmap protein networkhttps://string-db.org/network/10090.ENSMUSP00000101486Noncompact myelin-associated protein; Plays a role in myelin formation.
Aunip protein networkhttps://string-db.org/network/10090.ENSMUSP00000101492Aurora kinase A and ninein-interacting protein; DNA-binding protein that accumulates at DNA double-strand breaks (DSBs) following DNA damage and promotes DNA resection and homologous recombinatio [...]
Pafah2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101496Platelet-activating factor acetylhydrolase 2, cytoplasmic; Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the [...]
Slc30a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101500Zinc transporter 2; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
Trim63 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101501E3 ubiquitin-protein ligase TRIM63; E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of musc [...]
Zfp683 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101508Tissue-resident T-cell transcription regulator protein ZNF683; Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T-cell [...]
Rps6ka1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101514Ribosomal protein S6 kinase alpha-1; Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the [...]
LTO1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101515Protein LTO1 homolog; The complex LTO1:YAE1 functions as a target specific adapter that probably recruits apo-ABCE1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be r [...]
Arid1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000101517AT-rich interactive domain-containing protein 1A; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component [...]
Fgf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101518Fibroblast growth factor 3; Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal ear development (By similarity); [...]
Shank2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101520SH3 and multiple ankyrin repeat domains protein 2; Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membran [...]
Tmem222 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101527Transmembrane protein 222.
Cd164l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101530CD164 sialomucin-like 2 protein.
Gpr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101531G-protein coupled receptor 3; Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Has a potential role in modulating a number of brain functions, including behavio [...]
Ahdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101536AT-hook DNA-binding motif-containing protein 1.
Slc22a18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101537Solute carrier family 22 member 18; May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related [...]
Lsp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101588Lymphocyte-specific protein 1; May play a role in mediating neutrophil activation and chemotaxis.
Ifitm10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101608Interferon-induced transmembrane protein 10; Belongs to the CD225/Dispanin family.
Nkain1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101614Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1.
Snrnp40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101616U5 small nuclear ribonucleoprotein 40 kDa protein; Required for pre-mRNA splicing as component of the activated spliceosome. Component of the U5 small nuclear ribonucleoprotein (snRNP) complex an [...]
Serinc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101618Serine incorporator 2.
Tinagl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101620Tubulointerstitial nephritis antigen-like; May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells. This is a non cat [...]
Cd151 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101622CD151 antigen; Essential for the proper assembly of the glomerular and tubular basement membranes in kidney; Belongs to the tetraspanin (TM4SF) family.
Gatd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101630Glutamine amidotransferase-like class 1 domain-containing protein 1.
Adgrb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101636Adhesion G protein-coupled receptor B2; Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription facto [...]
Phrf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101648PHD and RING finger domain-containing protein 1.
Pkp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101654Plakophilin-3; May play a role in junctional plaques.
Ifitm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101657Interferon-induced transmembrane protein 1; IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral f [...]
Fam229a protein networkhttps://string-db.org/network/10090.ENSMUSP00000101658Protein FAM229A; Belongs to the FAM229 family.
Urah protein networkhttps://string-db.org/network/10090.ENSMUSP000001016655-hydroxyisourate hydrolase; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate h [...]
Zfp941 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101667Zinc finger protein 941.
Yars protein networkhttps://string-db.org/network/10090.ENSMUSP00000101669Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then [...]
Zranb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101673Zinc finger Ran-binding domain-containing protein 2; Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection (By simi [...]
S100pbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000101676S100P-binding protein.
Tmem54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101679Transmembrane protein 54.
Adam8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101684Disintegrin and metalloproteinase domain-containing protein 8; Possible involvement in extravasation of leukocytes.
Zfp362 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101686Zinc finger protein 362.
Gjb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101696Gap junction beta-4 protein; Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hex [...]
Dlgap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101700Disks large-associated protein 3; May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoske [...]
Nkx6-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101701NK6 homeobox 2.
Zzz3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101706ZZ-type zinc finger-containing protein 3; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Zmym1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101708Zinc finger, MYM domain-containing 1.
Rab40b protein networkhttps://string-db.org/network/10090.ENSMUSP00000101713Ras-related protein Rab-40B; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequ [...]
Zmym4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101714Zinc finger MYM-type protein 4; Plays a role in the regulation of cell morphology and cytoskeletal organization.
Bnip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101718BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellu [...]
Foxk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101719Forkhead box protein K2; Transcriptional regulator involved in different processes such as glucose metabolism, aerobic glycolysis and autophagy. Recognizes and binds the forkhead DNA sequence mot [...]
Hexdc protein networkhttps://string-db.org/network/10090.ENSMUSP00000101723Hexosaminidase D; Has hexosaminidase activity. Responsible for the cleavage of the monosaccharides N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc) from cellular substrates. Has a [...]
Ssx2ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000101759Afadin- and alpha-actinin-binding protein; Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Ma [...]
Cenpx protein networkhttps://string-db.org/network/10090.ENSMUSP00000101760Centromere protein X; DNA-binding component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 comple [...]
Zranb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101763Ubiquitin thioesterase Zranb1; Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'- [...]
Csf3r protein networkhttps://string-db.org/network/10090.ENSMUSP00000101768Granulocyte colony-stimulating factor receptor; Receptor for granulocyte colony-stimulating factor (CSF3). In addition it may function in some adhesion or recognition events at the cell surface.
Notum protein networkhttps://string-db.org/network/10090.ENSMUSP00000101783Palmitoleoyl-protein carboxylesterase NOTUM; Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Ser [...]
Npb protein networkhttps://string-db.org/network/10090.ENSMUSP00000101801Neuropeptide B-29; Has an effect in food intake, on locomotor activity and has an analgesic effect, (in vivo pharmacological studies). May be involved in the regulation of neuroendocrine system, [...]
Hgs protein networkhttps://string-db.org/network/10090.ENSMUSP00000101809Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA [...]
Ndufs5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101813NADH dehydrogenase [ubiquinone] iron-sulfur protein 5; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in cat [...]
Kyat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101825Kynurenine--oxoglutarate transaminase 3; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S- [...]
Gbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101828Guanylate-binding protein 4; Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation.
Ndufaf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101830NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8; Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I, MT-ND1). Required to stabilize N [...]
Tial1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101833Nucleolysin TIAR; RNA-binding protein. Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis (By similarity).
Cep131 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101834Centrosomal protein of 131 kDa; Component of centriolar satellites contributing to the building of a complex and dynamic network required to regulate cilia/flagellum formation. In proliferating c [...]
Endov protein networkhttps://string-db.org/network/10090.ENSMUSP00000101851Endonuclease V; Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine. Has strong preference for single-stranded RNAs (ss [...]
Adh6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000101854Alcohol dehydrogenase 6A (class V).
Trim72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101855Tripartite motif-containing protein 72; Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically [...]
Card14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101857Caspase recruitment domain-containing protein 14; Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms [...]
Fus protein networkhttps://string-db.org/network/10090.ENSMUSP00000101858RNA-binding protein FUS; DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response. Bin [...]
Cap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101864Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization a [...]
Gaa protein networkhttps://string-db.org/network/10090.ENSMUSP00000101866Lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans.
Gm12887 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101872Predicted gene 12887.
Stx1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000101874Syntaxin-1B; Potentially involved in docking of synaptic vesicles at presynaptic active zones (By similarity). May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm; Belongs to [...]
Tmco2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101875Transmembrane and coiled-coil domain-containing protein 2.
Zfp69 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101887Zinc finger protein 69; Putative transcription factor that appears to regulate lipid metabolism.
Cant1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101896Soluble calcium-activated nucleotidase 1; Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > IDP >> UTP > CDP = GTP = ITP. Ha [...]
Usp36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101903Ubiquitin carboxyl-terminal hydrolase 36; Deubiquitinase essential for the regulation of nucleolar structure and function. Required for cell and organism viability. Plays an important role in rib [...]
Zfp688 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101907Zinc finger protein 688.
Scmh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101908Polycomb protein SCMH1; Associates with Polycomb group (PcG) multiprotein complexes; the complex class is required to maintain the transcriptionally repressive state of some genes; Belongs to the [...]
Cyth1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101909Cytohesin-1; Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficki [...]
Itgal protein networkhttps://string-db.org/network/10090.ENSMUSP00000101913Integrin alpha-L; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is a receptor for F11R (By similarity). Integrin ITGAL/ITGB2 is a receptor for the sec [...]
Hivep3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101914Transcription factor HIVEP3; Plays a role of transcription factor; binds to recognition signal sequences (Rss heptamer) for somatic recombination of immunoglobulin and T-cell receptor gene segmen [...]
Zfp553 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101919Zinc finger protein 48; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Sept1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101921Septin-1; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Ppih protein networkhttps://string-db.org/network/10090.ENSMUSP00000101924Peptidyl-prolyl cis-trans isomerase H; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Participates in [...]
6030468B19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000101938Protein IL-40; Probable B cell-associated cytokine that plays a role in the regulation of humoral immune responses. Involved in lymphocyte B cell development and immunoglobulin/IgA production.
Sez6l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101940Seizure 6-like protein 2; May contribute to specialized endoplasmic reticulum functions in neurons.
Cyp2u1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101944Cytochrome P450 2U1; A cytochrome P450 monooxygenase involved in the metabolism of arachidonic acid and its conjugates. Mechanistically, uses molecular oxygen inserting one oxygen atom into a sub [...]
Asphd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101947Aspartate beta-hydroxylase domain-containing protein 1; Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
Tnrc6c protein networkhttps://string-db.org/network/10090.ENSMUSP00000101951Trinucleotide repeat-containing gene 6C protein; Plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs). Required for miRNA-dependent translational repression of complementary mRNAs b [...]
Ypel3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101964Protein yippee-like 3; Involved in proliferation and apoptosis in myeloid precursor cells.
Olfr1331 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101967Olfactory receptor 1331.
Olfr1330 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101968Olfactory receptor MOR259-8.
Coro1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000101972Coronin-1A; May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of th [...]
Mettl23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101978Methyltransferase-like protein 23; Probable methyltransferase.
Sult1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101980Sulfotransferase 1A1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransm [...]
Prpsap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000101999Phosphoribosyl pyrophosphate synthase-associated protein 1; Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis; Belongs to the ribose-phosphate pyrophosphokinase [...]
Kdm4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000102014Lysine-specific demethylase 4A; Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylat [...]
Rabep2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102015Rab GTPase-binding effector protein 2; Plays a role in membrane trafficking and in homotypic early endosome fusion. Participates in arteriogenesis by regulating vascular endothelial growth factor [...]
Synpo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102034Synaptopodin-2; Has an actin-binding and actin-bundling activity. Can induce the formation of F-actin networks. At the sarcomeric Z lines is proposed to act as adapter protein that links nascent [...]
1810037I17Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000102037Uncharacterized protein C4orf3 homolog.
Gm10959 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102039Predicted gene 10959.
Tmem53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102042Transmembrane protein 53; Belongs to the TMEM53 family.
Hs3st4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102045Sulfotransferase; Belongs to the sulfotransferase 1 family.
Mrpl38 protein networkhttps://string-db.org/network/10090.ENSMUSP0000010204739S ribosomal protein L38, mitochondrial.
Arhgap17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102050Rho GTPase-activating protein 17; Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarit [...]
Eif2b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102056Eukaryotic translation initiation factor 2B, subunit 3.
H3f3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000102062Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorpo [...]
Ccdc163 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102072Coiled-coil domain-containing 163.
Rwdd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102075RWD domain-containing protein 3; Enhancer of SUMO conjugation. Via its interaction with UBE2I/UBC9, increases SUMO conjugation to proteins by promoting the binding of E1 and E2 enzymes, thioester [...]
Plppr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102081Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory-mediated axonal retractio [...]
Tmem69 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102087Transmembrane protein 69.
Ipp protein networkhttps://string-db.org/network/10090.ENSMUSP00000102088Actin-binding protein IPP; May play a role in organizing the actin cytoskeleton.
Mast2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102095Microtubule-associated serine/threonine-protein kinase 2; Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modula [...]
1700042G07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000102101PIK3R3 upstream open reading frame protein.
Mif4gd protein networkhttps://string-db.org/network/10090.ENSMUSP00000102116MIF4G domain-containing protein; Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loo [...]
Mknk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102123MAP kinase-interacting serine/threonine-protein kinase 1; May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus inc [...]
Tex38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102131Testis-expressed protein 38.
Acsm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102138Acyl-coenzyme A synthetase ACSM3, mitochondrial; Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain [...]
Atp5h protein networkhttps://string-db.org/network/10090.ENSMUSP00000102147ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
Hid1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102152Protein HID1; Belongs to the hid-1 family.
Iqck protein networkhttps://string-db.org/network/10090.ENSMUSP00000102157IQ motif-containing K.
Knop1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102160Lysine-rich nucleolar protein 1.
Grin2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000102164Glutamate receptor ionotropic, NMDA 2C; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sens [...]
Ccp110 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102167Centriolar coiled-coil protein of 110 kDa; Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration wi [...]
Cd300lf protein networkhttps://string-db.org/network/10090.ENSMUSP00000102171CMRF35-like molecule 1; Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recog [...]
Skint4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102176Selection and upkeep of intraepithelial T-cells protein 4; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus.
Cd300lb protein networkhttps://string-db.org/network/10090.ENSMUSP00000102191CMRF35-like molecule 7; Acts as an activating immune receptor in mast cells through its interaction with ITAM-bearing adapter TYROBP.
Cd300a protein networkhttps://string-db.org/network/10090.ENSMUSP00000102192CMRF35-like molecule 8; Inhibitory receptor which may contribute to the down- regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. [...]
Gpr142 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102194Probable G-protein coupled receptor 142; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Elavl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102207ELAV-like protein 4; RNA-binding protein that is involved in the post- transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. [...]
Rpl38 protein networkhttps://string-db.org/network/10090.ENSMUSP0000010220960S ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.
Clcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102224Chloride channel CLIC-like protein 1; Seems to act as a chloride ion channel (By similarity). Plays a role in retina development. Belongs to the chloride channel MCLC family.
Cdc42ep4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102227Cdc42 effector protein 4; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pse [...]
Ttc39a protein networkhttps://string-db.org/network/10090.ENSMUSP00000102229Tetratricopeptide repeat protein 39A.
5330417C22Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000102236UPF0577 protein KIAA1324; May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway.
Slc39a11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102244Zinc transporter ZIP11; Functions as a cellular zinc transporter.
Nrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102255Nardilysin; Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.
Rab3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000102261Ras-related protein Rab-3B; Protein transport. Probably involved in vesicular traffic (By similarity).
Cyb561d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102266Cytochrome b561 domain-containing protein 1.
Amigo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102267Amphoterin-induced protein 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. [...]
Zfyve9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102268Zinc finger FYVE domain-containing protein.
Prkar1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000102288cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
Gstm6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102296Glutathione S-transferase Mu 6; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Podn protein networkhttps://string-db.org/network/10090.ENSMUSP00000102320Podocan; Negatively regulates cell proliferation and cell migration, especially in smooth muscle cells.
Scube2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102340Signal peptide, CUB and EGF-like domain-containing protein 2; Lipid-binding protein required for SHH long-range signaling by binding to the dually lipid-modified SHH (ShhNp) and by promoting ShhN [...]
Lrp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102342Low-density lipoprotein receptor-related protein 8; Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Ree [...]
Trim66 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102352Tripartite motif-containing protein 66; May function as transcription repressor; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as [...]
Stk33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102356Serine/threonine-protein kinase 33; Serine/threonine protein kinase which phosphorylates VIME. May play a specific role in the dynamic behavior of the intermediate filament cytoskeleton by phosph [...]
Ovch2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102366Ovochymase-2; Belongs to the peptidase S1 family.
Cyb5rl protein networkhttps://string-db.org/network/10090.ENSMUSP00000102369NADH-cytochrome b5 reductase-like; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methem [...]
Capza1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102381F-actin-capping protein subunit alpha-1; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of sub [...]
Mroh7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102382Maestro heat-like repeat-containing protein family member 7.
Pars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102393Probable proline--tRNA ligase, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family.
Timm10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000102395Mitochondrial import inner membrane translocase subunit Tim10 B; Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mit [...]
Lexm protein networkhttps://string-db.org/network/10090.ENSMUSP00000102400Lymphocyte expansion molecule.
Pecam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102408Platelet endothelial cell adhesion molecule; Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (By similarity). Tyr-679 pl [...]
Fyb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102415FYN-binding protein 2; Adapter protein that plays a role in T-cell receptor (TCR)- mediated activation of signaling pathways. Required for T-cell activation and integrin-mediated T-cell adhesion [...]
Gm5901 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102417Predicted gene 5901.
Trim30c protein networkhttps://string-db.org/network/10090.ENSMUSP00000102441Tripartite motif-containing 30C.
Dab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102443Disabled homolog 1; Adapter molecule functioning in neural development. May regulate SIAH1 activity.
Trim12a protein networkhttps://string-db.org/network/10090.ENSMUSP00000102452Tripartite motif-containing protein 12A; Belongs to the TRIM/RBCC family.
Trim34b protein networkhttps://string-db.org/network/10090.ENSMUSP00000102460Tripartite motif-containing 34B.
Olfr649 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102472Olfactory receptor.
Olfr631 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102476Olfactory receptor.
Hbb-bh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102479Predicted gene, EG436003; Belongs to the globin family.
Wdr78 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102481WD repeat-containing protein 78.
Insl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102482Insulin-like peptide INSL5 A chain; May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for thi [...]
Olfr69 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102491Olfactory receptor.
Olfr630 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102493Olfactory receptor.
Olfr613 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102501Olfactory receptor 613.
Olfr592 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102506Olfactory receptor.
Cxcr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102512C-X-C chemokine receptor type 2; Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is m [...]
Pde4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000102521Phosphodiesterase.
Gm12789 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102527Predicted gene 12789.
B020004J07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000102532RIKEN cDNA B020004J07 gene.
Rhog protein networkhttps://string-db.org/network/10090.ENSMUSP00000102536Rho-related GTP-binding protein RhoG; Required for the formation of membrane ruffles during macropinocytosis. Plays a role in cell migration and is required for the formation of cup-like structur [...]
Ngf protein networkhttps://string-db.org/network/10090.ENSMUSP00000102538Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptor [...]
Slc22a15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102541Solute carrier family 22 member 15; Probably transports organic cations. Appears not to be the agmatine transporter.
Dnajc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102546Putative tyrosine-protein phosphatase auxilin; Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles. Plays a role in clathrin- mediated endocytosis [...]
Art5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102550Ecto-ADP-ribosyltransferase 5; Belongs to the Arg-specific ADP-ribosyltransferase family.
Tlk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102554Serine/threonine-protein kinase tousled-like 2; Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromos [...]
Ak4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102559Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates (By similarity). Efficiently phosphor [...]
Xndc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102563Xndc1-transient receptor potential cation channel, subfamily C, member 2 readthrough.
Myl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102570Myosin light chain 4; Regulatory light chain of myosin. Does not bind calcium.
Tomt protein networkhttps://string-db.org/network/10090.ENSMUSP00000102582Transmembrane O-methyltransferase homolog; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Required for auditory function. Com [...]
Kansl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102590KAT8 regulatory NSL complex subunit 1; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulatio [...]
Folr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102598Folate receptor alpha; Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for fo [...]
Sppl2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000102613Signal peptide peptidase-like 2C; Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane.
Arf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102622ADP-ribosylation factor 2; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may mo [...]
Arap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102624Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase- activating protein that modulates actin cytoskeleton remodel [...]
Hsd3b1 protein networkhttps://string-db.org/network/10090.ENSMUSP000001026303 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; A bifunctional enzyme responsible for the oxidation and isomerization of 3beta-hydroxy-Delta(5)-steroid precursors to 3-oxo- Delt [...]
Hsd3b3 protein networkhttps://string-db.org/network/10090.ENSMUSP000001026333 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 3; 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxid [...]
Hsd3b2 protein networkhttps://string-db.org/network/10090.ENSMUSP000001026363 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2; 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxid [...]
Arhgap27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102639Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an ina [...]
Arhgef17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102647Rho guanine nucleotide exchange factor 17; Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases.
Fmo5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102665Dimethylaniline monooxygenase [N-oxide-forming] 5; In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme.
Pdzk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102685Na(+)/H(+) exchange regulatory cofactor NHE-RF3; A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apica [...]
Gm12695 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102686Uncharacterized protein C1orf87 homolog.
Cd160 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102689CD160 antigen, soluble form; [CD160 antigen]: Receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anch [...]
Gjc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102690Gap junction gamma-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a [...]
Gm11627 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102696Predicted gene 11627.
Chrdl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102699Chordin-like protein 2; Implicated in tumor angiogenesis (By similarity). May inhibits BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the car [...]
Slco2b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102703Solute carrier organic anion transporter family member 2B1; Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, t [...]
Ankrd34a protein networkhttps://string-db.org/network/10090.ENSMUSP00000102707Ankyrin repeat domain 34A.
Txnip protein networkhttps://string-db.org/network/10090.ENSMUSP00000102710Thioredoxin-interacting protein; May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced sup [...]
Jun protein networkhttps://string-db.org/network/10090.ENSMUSP00000102711Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to incre [...]
Bola1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102716BolA-like protein 1; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably [...]
Lrrc19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102718Leucine-rich repeat-containing protein 19.
Plaa protein networkhttps://string-db.org/network/10090.ENSMUSP00000102724Phospholipase A-2-activating protein; Plays a role in protein ubiquitination, sorting and degradation through its association with VCP (By similarity). Involved in ubiquitin-mediated membrane pro [...]
Izumo3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102725Izumo sperm-egg fusion protein 3.
Elavl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102737ELAV-like protein 2; RNA-binding protein that binds to the 3' untranslated region (3'UTR) of target mRNAs. Seems to recognize a GAAA motif. Can bind to its own 3'UTR, the FOS 3'UTR and the ID 3'U [...]
Myo7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000102745Unconventional myosin-VIIa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous [...]
Zfp352 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102746Zinc finger protein 352.
Cdkn2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000102748Tumor suppressor ARF; Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nuc [...]
BC028528 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102749Uncharacterized protein C1orf54 homolog.
Atxn7l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102750Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediatin [...]
Rsf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102771Remodeling and spacing factor 1.
Slc24a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102776Solute carrier family 24 (sodium/potassium/calcium exchanger), member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
Cd300lg protein networkhttps://string-db.org/network/10090.ENSMUSP00000102782CMRF35-like molecule 9; Receptor which may mediate L-selectin-dependent lymphocyte rollings. Binds SELL in a calcium dependent manner. Binds lymphocyte. Belongs to the CD300 family.
Tenm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102783Teneurin-4; Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Plays a role in the establishment of the anterior-posterior axis during [...]
Mpp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102786MAGUK p55 subfamily member 3; Belongs to the MAGUK family.
Dusp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102790Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dep [...]
Adamtsl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102796ADAMTS-like protein 1.
Anxa9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102801Annexin A9; May act as a low affinity receptor for acetylcholine. Belongs to the annexin family.
Mindy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102805Ubiquitin carboxyl-terminal hydrolase MINDY-1; Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for l [...]
Bnipl protein networkhttps://string-db.org/network/10090.ENSMUSP00000102813Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein; May be a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death.
Dlg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102814Disks large homolog 2; Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts [...]
Ccdc83 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102839Coiled-coil domain-containing protein 83.
Tmod4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102846Tropomodulin-4; Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in t [...]
Pip5k1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000102852Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; Catalyzes the phosphorylation of phosphatidylinositol 4- phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) [...]
Eed protein networkhttps://string-db.org/network/10090.ENSMUSP00000102853Polycomb protein EED; Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affec [...]
Rpl27 protein networkhttps://string-db.org/network/10090.ENSMUSP0000010287060S ribosomal protein L27; Component of the large ribosomal subunit (By similarity). Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (By similarity).
Pi4kb protein networkhttps://string-db.org/network/10090.ENSMUSP00000102872Phosphatidylinositol 4-kinase beta; Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regula [...]
Rab38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102877Ras-related protein Rab-38; Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and Mycobacterium (By similarity). May be involved in melanosomal transport and do [...]
Gm27029 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102880Predicted gene, 27029.
Pogz protein networkhttps://string-db.org/network/10090.ENSMUSP00000102891Pogo transposable element with ZNF domain; Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its assoc [...]
Vps25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102901Vacuolar protein-sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation [...]
Snx27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102904Sorting nexin-27; Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following intern [...]
Ezh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102906Histone-lysine N-methyltransferase EZH1; Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repressi [...]
Hdgfl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102926Hepatoma-derived growth factor-related protein 3; Enhances DNA synthesis and may play a role in cell proliferation.
Coasy protein networkhttps://string-db.org/network/10090.ENSMUSP00000102929Phosphopantetheine adenylyltransferase; Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantet [...]
Gm13871 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102940Predicted gene, OTTMUSG00000014862.
Sprr2a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102950Small proline-rich protein 2A2.
S100a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102952Protein S100-A5; Binds calcium, zinc and copper. One subunit can simultaneously bind 2 calcium ions or 2 copper ions plus 1 zinc ion. Calcium and copper ions compete for the same binding sites (B [...]
Alpk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102971Alpha-protein kinase 3; Involved in cardiomyocyte differentiation.
Zfp592 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102976Zinc finger protein 592; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Stat5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000102980Signal transducer and activator of transcription.
Stat5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000102981Signal transducer and activator of transcription 5B; Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and ot [...]
Megf9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102982Multiple epidermal growth factor-like domains protein 9.
Kcnh4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000102986Potassium Voltage-gated channel, subfamily H (Eag-related), member 4.
Tnc protein networkhttps://string-db.org/network/10090.ENSMUSP00000103000Tenascin; Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outg [...]
Idh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103007Isocitrate dehydrogenase [NADP], mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex; Belong [...]
Acly protein networkhttps://string-db.org/network/10090.ENSMUSP00000103012ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the C-termina [...]
Anpep protein networkhttps://string-db.org/network/10090.ENSMUSP00000103015Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved i [...]
Mesp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103017Mesoderm posterior protein 2.
Adar protein networkhttps://string-db.org/network/10090.ENSMUSP00000103028Double-stranded RNA-specific adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect ge [...]
Krt15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103034Keratin, type I cytoskeletal 15; In the absence of KRT14, makes a bona fide, but ultrastructurally distinct keratin filament network with KRT5. Belongs to the intermediate filament family.
Krt36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103039Keratin, type I cuticular Ha6; Belongs to the intermediate filament family.
Krt32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103042Keratin, type I cuticular Ha2; Belongs to the intermediate filament family.
Aen protein networkhttps://string-db.org/network/10090.ENSMUSP00000103048Apoptosis-enhancing nuclease; Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-s [...]
Gm11568 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103057Predicted gene 11568.
Zbtb7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000103058Zinc finger and BTB domain-containing protein 7B; Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Exerts distinct biological functions in [...]
Krtap4-16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103060Keratin associated protein 4-16.
Krtap4-8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103063Keratin associated protein 4-8.
Gm11595 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103064Predicted gene 11595.
Alad protein networkhttps://string-db.org/network/10090.ENSMUSP00000103068Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes t [...]
Krt39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103069Keratin, type I cytoskeletal 39; May play a role in late hair differentiation.
Rnf183 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103079E3 ubiquitin-protein ligase RNF183; Acts as a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Triggers apoptosis in response to prolonged ER [...]
Fam174b protein networkhttps://string-db.org/network/10090.ENSMUSP00000103080Membrane protein FAM174B; Essential for Golgi structural integrity. Belongs to the FAM174 family.
Dpm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103086Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit DPM1 to the ER. Belongs to the DPM3 family [...]
Rapgefl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103103Rap guanine nucleotide exchange factor-like 1; Probable guanine nucleotide exchange factor (GEF).
Mup16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103107Major urinary protein 16.
Mup17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103108Major urinary protein 17; Major urinary proteins (Mups) bind pheromones, thus stabilize them and allow slow release into the air from urine marks. May protect pheromones from oxidation. May also [...]
Mup3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103112Major urinary protein 3; Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females; Belongs to the calycin superfamily. Lipocalin famil [...]
Gon4l protein networkhttps://string-db.org/network/10090.ENSMUSP00000103122GON-4-like protein; Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A AND HDAC1. Required for B cell lymphopoiesis.
Syt11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103129Synaptotagmin-11; Synaptotagmin family member involved in vesicular and membrane trafficking which does not bind Ca(2+) (Probable). Inhibits clathrin-mediated and bulk endocytosis, functions to e [...]
Mup6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103141Novel member of the major urinary protein (Mup) gene family; Belongs to the calycin superfamily. Lipocalin family.
Cdk12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103162Cyclin-dependent kinase 12; Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transc [...]
Bglap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103166Osteocalcin-related protein; Binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family.
Med1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103169Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Me [...]
Shoc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103171Protein shortage in chiasmata 1 ortholog; ATPase required during meiosis for the formation of crossover recombination intermediates. Binds DNA: preferentially binds to single-stranded DNA and DNA [...]
Zkscan16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103178Zinc finger with KRAB and SCAN domains 16.
Tsacc protein networkhttps://string-db.org/network/10090.ENSMUSP00000103180TSSK6-activating co-chaperone protein; Co-chaperone that facilitates HSP-mediated activation of TSSK6.
Mef2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000103184Myocyte-specific enhancer factor 2D; Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-indu [...]
Plxdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103191Plexin domain-containing protein 1; Plays a critical role in endothelial cell capillary morphogenesis.
Lpar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103197Lysophosphatidic acid receptor 1; Receptor for lysophosphatidic acid (LPA). Plays a role in the reorganization of the actin cytoskeleton, cell migration, differentiation and proliferation, and th [...]
1700001P01Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000103202Uncharacterized protein C17orf98 homolog.
Sh2d2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000103207SH2 domain-containing protein 2A; Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in p56-LCK-mediated T- cell signaling. Could be involved [...]
Cisd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103209CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maint [...]
Gas2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103217Growth arrest-specific protein 2; May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements o [...]
Srcin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103222SRC kinase signaling inhibitor 1; Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Reg [...]
Arhgap23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103227Rho GTPase-activating protein 23; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Tmem245 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103234Transmembrane protein 245.
Tbkbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103240TANK-binding kinase 1-binding protein 1; Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Essential for the efficient induction of IRF-depend [...]
Kirrel protein networkhttps://string-db.org/network/10090.ENSMUSP00000103243Kin of IRRE-like protein 1; Plays a significant role in the normal development and function of the glomerular permeability. Is a signaling protein that needs the presence of TEC kinases to fully [...]
Klf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103245Krueppel-like factor 4; Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its ow [...]
Sp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103248Transcription factor Sp6; Promotes cell proliferation; Belongs to the Sp1 C2H2-type zinc-finger protein family.
Sp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103250Transcription factor Sp2; Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Belongs to the Sp1 C2H2-type zinc-finge [...]
Lrba protein networkhttps://string-db.org/network/10090.ENSMUSP00000103261Lipopolysaccharide-responsive and beige-like anchor protein; May be involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of im [...]
Prr15l protein networkhttps://string-db.org/network/10090.ENSMUSP00000103262Proline-rich protein 15-like protein; Belongs to the PRR15 family.
Gtf2h1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103271General transcription factor IIH subunit 1; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotid [...]
Olfr273 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103297Olfactory receptor.
Toporsl protein networkhttps://string-db.org/network/10090.ENSMUSP00000103298Topoisomerase I-binding, arginine/serine-rich-like.
Fbxw7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103306F-box/WD repeat-containing protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent prote [...]
Tmem154 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103310Transmembrane protein 154.
Fhdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103317FH2 domain-containing protein 1; Microtubule-associated formin which regulates both actin and microtubule dynamics. Induces microtubule acetylation and stabilization and actin stress fiber format [...]
Zfp189 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103324Zinc finger protein 189.
Msantd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103332Myb/SANT-like DNA-binding domain-containing protein 3; Belongs to the MSANTD3 family.
Zfp652 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103345Zinc finger protein 652; Functions as a transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family.
Stx17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103348Syntaxin-17; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemb [...]
Spop protein networkhttps://string-db.org/network/10090.ENSMUSP00000103350Speckle-type POZ protein; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their [...]
Cyth2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103357Cytohesin-2; Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Activates ARF factors through replacement of GDP with GTP. The cell m [...]
Kat7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103362Histone acetyltransferase KAT7; Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of h [...]
Sphk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103366Sphingosine kinase 2; Catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dih [...]
Ntn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103371Netrin-5; Plays a role in neurogenesis. Prevents motor neuron cell body migration out of the neural tube.
Gabbr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103378Gamma-aminobutyric acid type B receptor subunit 2; Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABB [...]
Hsd17b14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103381Hydroxysteroid (17-beta) dehydrogenase 14.
Coro2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000103386Coronin-2A.
Tulp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103391Tubby-related protein 2.
Hemgn protein networkhttps://string-db.org/network/10090.ENSMUSP00000103393Hemogen; Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell [...]
Tstd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103401Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2.
Tmod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103402Tropomodulin-1; Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in t [...]
Kcna7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103403Potassium voltage-gated channel subfamily A member 7; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the [...]
Tdrd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103406Tudor domain-containing protein 7; Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and reg [...]
Zbbx protein networkhttps://string-db.org/network/10090.ENSMUSP00000103407Zinc finger B-box domain-containing protein 1.
Stra6l protein networkhttps://string-db.org/network/10090.ENSMUSP00000103412Stimulated by retinoic acid gene 6 protein-like; Acts as a high-affinity cell-surface receptor for retinol- binding protein RBP4 and mediates RBP4-dependent retinol uptake in the liver.
Tead2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103431Transcriptional enhancer factor TEF-4; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting pr [...]
Trim59 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103432Tripartite motif-containing protein 59; May serve as a multifunctional regulator for innate immune signaling pathways; Belongs to the TRIM/RBCC family.
Frmpd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103434FERM and PDZ domain-containing protein 1; Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1.
Tomm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103438Mitochondrial import receptor subunit TOM5 homolog.
Ift80 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103442Intraflagellar transport protein 80 homolog; Component of the intraflagellar transport (IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia.
Il12a protein networkhttps://string-db.org/network/10090.ENSMUSP00000103446Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the producti [...]
Ankrd40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103448Ankyrin repeat domain-containing protein 40.
Zcchc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103454Zinc finger CCHC domain-containing protein 7.
Prmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103474Protein arginine N-methyltransferase 1; Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1 [...]
Clta protein networkhttps://string-db.org/network/10090.ENSMUSP00000103483Clathrin light chain A; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Acts as component of the TACC3/ch- TOG/clathrin complex proposed to contribute to stabili [...]
Mbtd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103485MBT domain-containing protein 1; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering [...]
Olfr155 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103492Olfactory receptor.
Car10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103495Carbonic anhydrase-related protein 10; Does not have a catalytic activity.
Tmem8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000103497Transmembrane protein 8B; May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion (By similarity); Belongs to the [...]
Tom1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103500TOM1-like protein 1; Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activ [...]
Akt1s1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103514Proline-rich AKT1 substrate 1; Subunit of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino [...]
Msmp protein networkhttps://string-db.org/network/10090.ENSMUSP00000103516Prostate-associated microseminoprotein; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response [...]
Rgp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103518RAB6A-GEF complex partner protein 2; The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required [...]
Dgke protein networkhttps://string-db.org/network/10090.ENSMUSP00000103526Diacylglycerol kinase epsilon; Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the sy [...]
Trim25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103528E3 ubiquitin/ISG15 ligase TRIM25; Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58 and IFIH1. M [...]
Elobl protein networkhttps://string-db.org/network/10090.ENSMUSP00000103534Elongin B-like.
Kcnc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103540Potassium voltage-gated channel subfamily C member 3; Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in r [...]
Tpm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103546Tropomyosin beta chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate [...]
Selenot protein networkhttps://string-db.org/network/10090.ENSMUSP00000103557Thioredoxin reductase-like selenoprotein T; Selenoprotein with thioredoxin reductase-like oxidoreductase activity (By similarity). Protects dopaminergic neurons against oxidative stress ans cell [...]
Fam71e1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103560Protein FAM71E1.
Shank1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103571SH3 and multiple ankyrin repeat domains protein 1; Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membran [...]
Atp8b5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103575Phospholipid-transporting ATPase FetA; P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membr [...]
Unc13b protein networkhttps://string-db.org/network/10090.ENSMUSP00000103586Protein unc-13 homolog B; Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in syn [...]
Fam214b protein networkhttps://string-db.org/network/10090.ENSMUSP00000103592Protein FAM214B; Belongs to the FAM214 family.
Klk6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103602Kallikrein-related-peptidase 6; Belongs to the peptidase S1 family.
Klk12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103604Kallikrein-related-peptidase 12; Belongs to the peptidase S1 family.
Zfp658 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103606Zinc finger protein 658.
Iglon5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103608IgLON family member 5.
Phf24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103609PHD finger protein 24.
Fam205a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103613Family with sequence similarity 205, member A1.
Gm12394 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103615Predicted gene 12394.
4930578G10Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000103618RIKEN cDNA 4930578G10 gene.
Ccl27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103621Predicted 2506.
Zfp975 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103626Zinc finger protein.
Zfp619 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103650Zinc finger protein 619.
Gm5114 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103652Predicted gene 5114.
Gm13306 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103653Predicted gene 13306.
Ptrh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103656Peptidyl-tRNA hydrolase 2, mitochondrial; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
Ccne1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103658G1/S-specific cyclin-E1; Essential for the control of the cell cycle at the G1/S (start) transition.
Fam205a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103661Protein FAM205A-2.
Ccl27a protein networkhttps://string-db.org/network/10090.ENSMUSP00000103671Chemokine (C-C motif) ligand 27A.
Il18r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103679Interleukin-18 receptor 1; Within the IL18 receptor complex, responsible for the binding of the proinflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from [...]
Tbx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103682T-box transcription factor TBX4; Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.
Fam219a protein networkhttps://string-db.org/network/10090.ENSMUSP00000103687Protein FAM219A; Belongs to the FAM219 family.
Kif24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103690Kinesin-like protein KIF24; Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading [...]
4931406P16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000103709RIKEN cDNA 4931406P16 gene.
Usp32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103710Ubiquitin-specific peptidase 32; Belongs to the peptidase C19 family.
Abhd18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103712Protein ABHD18; Belongs to the AB hydrolase superfamily.
Ggnbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103716Gametogenetin-binding protein 2; May be involved in spermatogenesis.
Scgb1b30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103718Secretoglobin, family 1B, member 30.
Scgb1b24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103722Secretoglobin, family 1B, member 24.
Scgb2b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103725Secretoglobin, family 2B, member 3.
Scgb1b29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103729Secretoglobin, family 1B, member 29.
Scgb1b7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103732Secretoglobin, family 1B, member 7.
Gm5148 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103740Predicted gene, EG381438.
Spry1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103742Protein sprouty homolog 1; May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis; Belongs to the sprouty family.
Spata5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103747ATPase family protein 2 homolog; ATP-dependent chaperone which uses the energy provided by ATP hydrolysis to generate mechanical force to disassemble protein complexes (By similarity). May be inv [...]
C9orf72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103762Guanine nucleotide exchange C9orf72 homolog; Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, [...]
Smim8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103768Small integral membrane protein 8.
Mmp28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103772Matrix metallopeptidase 28 (epilysin).
Etv2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103782ETS translocation variant 2; Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
Zbtb32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103786Zinc finger and BTB domain-containing protein 32; DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional r [...]
Rngtt protein networkhttps://string-db.org/network/10090.ENSMUSP00000103788Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. [...]
Kmt2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000103789Histone-lysine N-methyltransferase 2B; Histone methyltransferase that methylates 'Lys-4' of histone H3 (By similarity). H3 'Lys-4' methylation represents a specific tag for epigenetic transcripti [...]
Bbs7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103791Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is [...]
Proser3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103800Proline and serine-rich protein 3.
Bach2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103815Transcription regulator protein BACH2; Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Plays an important role in coordinating transcripti [...]
Dcun1d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103817DCN1-like protein 1; Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 [...]
Ccl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103824C-C motif chemokine 1; Cytokine that is chemotactic for neutrophils; Belongs to the intercrine beta (chemokine CC) family.
Wdr62 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103825WD repeat-containing protein 62; Required for cerebral cortical development. Plays a role in neuronal proliferation and migration (By similarity). Plays a role in mother-centriole-dependent centr [...]
Fhl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103839Four and a half LIM domains protein 5; May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation- independent manner (By similarity).
Zfp74 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103840Zinc finger protein 569; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Ttc14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103845Tetratricopeptide repeat protein 14.
Klhl32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103853Kelch-like 32.
Mms22l protein networkhttps://string-db.org/network/10090.ENSMUSP00000103857Protein MMS22-like; Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is requ [...]
Wwp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103881NEDD4-like E3 ubiquitin-protein ligase WWP1; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the [...]
Prkci protein networkhttps://string-db.org/network/10090.ENSMUSP00000103884Protein kinase C iota type; Calcium- and diacylglycerol-independent serine/ threonine- protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B act [...]
Gpr160 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103896Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Samd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103897Sterile alpha motif domain-containing protein 7; Involved in the regulation of gene expression in the retina. It functions as a negative regulator of CRX-controlled genes.
Lrriq4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103902Leucine-rich repeat and IQ domain-containing protein 4.
Lgals9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103904Galectin-9; Binds galactosides (By similarity). Has high affinity for the Forssman pentasaccharide (By similarity). Ligand for HAVCR2/TIM3 (By similarity). Binding to HAVCR2 induces T-helper type [...]
Tnfaip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103912BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of c [...]
Fbxo27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103916F-box only protein 27; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind complex-type oligosaccharides.
Pak4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103918Serine/threonine-protein kinase PAK 4; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, growth, pr [...]
Fam92a protein networkhttps://string-db.org/network/10090.ENSMUSP00000103920Protein FAM92A; Acts as a positive regulator of ciliary hedgehog signaling. Probable regulator of ciliogenesis involved in limb morphogenesis. In cooperation with CBY1 it is involved in the recru [...]
Sarm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103922NAD(+) hydrolase SARM1; NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism. Acts as a negative regulator of MYD88- and TRIF-dependent [...]
Lrfn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103923Leucine-rich repeat and fibronectin type III domain-containing protein 1; Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Ind [...]
Gmfg protein networkhttps://string-db.org/network/10090.ENSMUSP00000103927Glia maturation factor gamma; Belongs to the actin-binding proteins ADF family. GMF subfamily.
Foxn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103929Forkhead box protein N1; Transcriptional regulator which regulates the development, differentiation, and function of thymic epithelial cells (TECs) both in the prenatal and postnatal thymus. Acts [...]
Unc119 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103930Protein unc-119 homolog A; Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacte [...]
Ect2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103935Protein ECT2; Guanine nucleotide exchange factor (GEF) that catalyzes the exchange of GDP for GTP. Promotes guanine nucleotide exchange on the Rho family members of small GTPases, like RHOA, RHOC [...]
Pdp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103937[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate [...]
Gem protein networkhttps://string-db.org/network/10090.ENSMUSP00000103939GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetec [...]
Rps16 protein networkhttps://string-db.org/network/10090.ENSMUSP0000010394040S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.
Virma protein networkhttps://string-db.org/network/10090.ENSMUSP00000103943Protein virilizer homolog; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRN [...]
Esrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103947Epithelial splicing regulatory protein 1; mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelia [...]
Dll3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103951Delta-like protein 3; Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmenta [...]
Rab34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103958Ras-related protein Rab-34; Protein transport. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and Mycobacterium. Plays a role in the fusion of phagosomes wit [...]
Cp protein networkhttps://string-db.org/network/10090.ENSMUSP00000103964Ceruloplasmin; Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It i [...]
Zfp60 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103973Zinc finger protein 60; May have a role during differentiation processes; Belongs to the krueppel C2H2-type zinc-finger protein family.
Akt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103981RAC-beta serine/threonine-protein kinase; AKT2 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinases, and which regulate many processes includi [...]
Ythdf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103983YTH domain-containing family protein 3; Specifically recognizes and binds N6-methyladenosine (m6A)- containing RNAs and promotes RNA translation efficiency (By similarity). M6A is a modification [...]
Hipk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103990Homeodomain-interacting protein kinase 4; Protein kinase that phosphorylates murine TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter. May act as a corepressor of transcription fa [...]
Gm9733 protein networkhttps://string-db.org/network/10090.ENSMUSP00000103998SIRP beta 1 like 2 protein.
Rbis protein networkhttps://string-db.org/network/10090.ENSMUSP00000104002Ribosomal biogenesis factor; Trans-acting factor in ribosome biogenesis required for efficient 40S and 60S subunit production.
Coq8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000104015Atypical kinase COQ8B, mitochondrial; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respi [...]
Sdr16c6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104020Short-chain dehydrogenase/reductase family 16C member 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Nlrp9a protein networkhttps://string-db.org/network/10090.ENSMUSP00000104024NACHT, LRR and PYD domains-containing protein 9A; May be involved in inflammation; Belongs to the NLRP family.
Hnf4g protein networkhttps://string-db.org/network/10090.ENSMUSP00000104030Hepatocyte nuclear factor 4-gamma; Transcription factor. Has a lower transcription activation potential than HNF4-alpha (By similarity); Belongs to the nuclear hormone receptor family. NR2 subfam [...]
Efcab5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104037EF-hand calcium-binding domain-containing protein 5.
Slc6a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104039Sodium-dependent serotonin transporter; Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin mol [...]
B9d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104040B9 domain-containing protein 2; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembran [...]
Tmem145 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104046Transmembrane protein 145.
Prr19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104047Proline-rich 19.
Pou2f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104056POU domain, class 2, transcription factor 2; Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to acti [...]
Rps19 protein networkhttps://string-db.org/network/10090.ENSMUSP0000010406840S ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS19 family.
Myo1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000104069Unconventional myosin-Ic; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous co [...]
Zfp94 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104075Zinc finger protein 94.
Zfp93 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104077Zinc finger protein 235; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Apoc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104091Truncated apolipoprotein C-I; Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Assoc [...]
Zfp296 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104093Zinc finger protein 296; May be a transcriptional corepressor with KLF4.
Ctns protein networkhttps://string-db.org/network/10090.ENSMUSP00000104116Cystinosin; Cystine/H(+) symporter thought to transport cystine out of lysosomes. Plays an important role in melanin synthesis, possibly by preventing melanosome acidification and subsequent degr [...]
Ceacam13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104128Carcinoembryonic antigen-related cell adhesion molecule 13.
Ceacam3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104131Carcinoembryonic antigen-related cell adhesion molecule 3.
Hif3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000104132Hypoxia-inducible factor 3-alpha; Acts as a transcriptional regulator in adaptive response to low oxygen tension. Acts as a regulator of hypoxia-inducible gene expression. Plays a role in the dev [...]
Dact3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104133Dapper homolog 3; May be involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathway [...]
Slc1a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104136Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all [...]
Ceacam15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104138Carcinoembryonic antigen-related cell adhesion molecule 15.
Fbxo39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104144F-box only protein 39; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Gm43951 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104146Protein moonraker; Involved in centriole duplication. Positively regulates CEP63 centrosomal localization. Required for WDR62 centrosomal localization and promotes the centrosomal localization of [...]
Wscd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104150WSC domain-containing protein 1; Belongs to the WSCD family.
Obox6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104153Oocyte-specific homeobox 6.
Nlrp1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000104155NACHT, LRR and PYD domains-containing protein 1b allele 2; As the sensor component of the NLRP1 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens an [...]
Nlrp1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000104158NACHT, LRR and PYD domains-containing protein 1a; As a potential sensor component of the NLRP1 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens and [...]
Sult2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104162Bile salt sulfotransferase 1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze sulfonation of hydroxysteroids and xenobiotics; Belongs to the su [...]
Sult2a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104164Sulfotransferase; Belongs to the sulfotransferase 1 family.
Sult2a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104165Sulfotransferase; Belongs to the sulfotransferase 1 family.
Bsph2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104166Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes.
Dhx33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104167ATP-dependent RNA helicase DHX33; Implicated in nucleolar organization, ribosome biogenesis, protein synthesis and cytoplasmic dsRNA sensing (By similarity). Stimulates RNA polymerase I transcrip [...]
Pla2g4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000104168Cytosolic phospholipase A2 gamma; Has a preference for arachidonic acid at the sn-2 position of phosphatidylcholine as compared with palmitic acid.
Zswim9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104172Uncharacterized protein ZSWIM9.
Scimp protein networkhttps://string-db.org/network/10090.ENSMUSP00000104174SLP adapter and CSK-interacting membrane protein; Lipid tetraspanin-associated transmembrane adapter/mediator that acts as a scaffold for Src-family kinases and other signaling proteins in immune [...]
Rps5 protein networkhttps://string-db.org/network/10090.ENSMUSP0000010417940S ribosomal protein S5, N-terminally processed; Belongs to the universal ribosomal protein uS7 family.
Eno3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104188Beta-enolase; Appears to have a function in striated muscle development and regeneration.
Pld2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104197Phospholipase D2; May have a role in signal-induced cytoskeletal regulation and/or endocytosis.
Zfp444 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104207Zinc finger protein 444.
Arrb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104208Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous d [...]
Vmn1r58 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104209Vomeronasal type-1 receptor.
Ccdc106 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104211Coiled-coil domain-containing protein 106; Promotes the degradation of p53/TP53 protein and inhibits its transactivity.
0610010K14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000104216Chromatin complexes subunit BAP18; Component of chromatin complexes such as the MLL1/MLL and NURF complexes.
Kmt5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000104223Histone-lysine N-methyltransferase KMT5C; Histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20' (H4K20me2) of histone H4 to produce r [...]
Tnnt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104228Troponin T, slow skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin A [...]
Dlg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104229Disks large homolog 4; Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. [...]
Ctdnep1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104234CTD nuclear envelope phosphatase 1; Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 [...]
Elp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104235Elongator complex protein 5; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in trans [...]
Pira2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104255Paired-Ig-like receptor A2.
Rps9 protein networkhttps://string-db.org/network/10090.ENSMUSP0000010426540S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family.
Tsen34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104270tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the spl [...]
Plscr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104273Phospholipid scramblase 3; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry [...]
Nlgn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104274Neuroligin-2; Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members. Mediates cell-cell interactions both in neurons and in other [...]
Zbtb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104279Zinc finger and BTB domain-containing protein 4; Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affi [...]
Tfpt protein networkhttps://string-db.org/network/10090.ENSMUSP00000104281TCF3 fusion partner homolog; Appears to promote apoptosis in a p53/TP53-independent manner.
Nlrp12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104293NACHT, LRR and PYD domains-containing protein 12; Plays an essential role as an potent mitigator of inflammation. Primarily expressed in dendritic cells and macrophages, inhibits both canonical a [...]
Sat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104296Diamine acetyltransferase 2; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine > spermidine = spermine >> N(1)acetylspermine = putrescine (By similarity).
Trp53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104298Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle r [...]
Dnah2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104299Dynein heavy chain 2, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke [...]
Chd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104301Chromodomain helicase DNA-binding protein 3.
Arhgef15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104311Rho guanine nucleotide exchange factor 15; Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synap [...]
Ntn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104314Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectiv [...]
Gas7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104322Growth arrest-specific protein 7; May play a role in promoting maturation and morphological differentiation of cerebellar neurons.
Myh13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104324Myosin, heavy polypeptide 13, skeletal muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Myh3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104329Myosin-3; Muscle contraction.
Myocd protein networkhttps://string-db.org/network/10090.ENSMUSP00000104335Myocardin; Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum respo [...]
Pmp22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104342Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system.
Drc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104363Dynein regulatory complex subunit 3; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the dist [...]
Slc35f3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104390Putative thiamine transporter SLC35F3; May be a thiamine transporter. Belongs to the SLC35F solute transporter family.
Jmjd4 protein networkhttps://string-db.org/network/10090.ENSMUSP000001044072-oxoglutarate and iron-dependent oxygenase JMJD4; Catalyzes the 2-oxoglutarate and iron-dependent C4-lysyl hydroxylation of ETF1 at 'Lys-63' thereby promoting the translational termination effic [...]
Rgs19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104408Regulator of G-protein signaling 19; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G [...]
Wnt9a protein networkhttps://string-db.org/network/10090.ENSMUSP00000104411Protein Wnt-9a; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Required for [...]
Mrpl55 protein networkhttps://string-db.org/network/10090.ENSMUSP0000010441439S ribosomal protein L55, mitochondrial.
Zfp512b protein networkhttps://string-db.org/network/10090.ENSMUSP00000104417Zinc finger protein 512B.
Gjc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104421Gap junction gamma-2 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a [...]
Trim11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104438E3 ubiquitin-protein ligase TRIM11; E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly- [...]
H2aw protein networkhttps://string-db.org/network/10090.ENSMUSP00000104445Histone H2A type 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones [...]
2210407C18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000104449RIKEN cDNA 2210407C18 gene.
Gm12253 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104453Predicted gene 12253.
Lypd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104454Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the larg [...]
Zfp672 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104457Zinc finger protein 672; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Helz2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104459Helicase with zinc finger domain 2; Helicase that acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA.
Def8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104460Differentially expressed in FDCP 8; Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption.
4930438A08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000104462Amine oxidase.
Cnot8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104471CCR4-NOT transcription complex subunit 8; Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalyti [...]
Fam114a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104478Protein FAM114A2.
Atox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104485Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family.
Slc36a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104500Proton-coupled amino acid transporter 1; Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Beside [...]
Birc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104503Baculoviral IAP repeat-containing protein 7 30 kDa subunit; Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell prolifera [...]
Bhlhe23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104506Class E basic helix-loop-helix protein 23; May function as transcriptional repressor. May modulate the expression of genes required for the differentiation and/or maintenance of pancreatic and ne [...]
Anxa6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104511Annexin A6; May associate with CD21. May regulate the release of Ca(2+) from intracellular stores; Belongs to the annexin family.
Cables2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104519CDK5 and ABL1 enzyme substrate 2; Unknown. Probably involved in G1-S cell cycle transition.
Mtg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104529Mitochondrial ribosome-associated GTPase 2.
Acsl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104533Long-chain-fatty-acid--CoA ligase 6; Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (By [...]
Phactr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104543Phosphatase and actin regulator 3.
Irf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104548Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-ind [...]
Zfp931 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104552Zinc finger protein 931.
Zfp971 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104554Zinc finger protein 971.
Gm14326 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104558Zinc finger protein.
Gm14327 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104563Predicted gene 14327.
Gm14325 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104567Predicted gene 14325.
Gm14406 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104573Predicted gene 14406.
Gm14403 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104575Predicted gene 14403.
Zfp966 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104577Zinc finger protein 966.
Gm14412 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104587Predicted gene 14412.
Gm14409 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104591Predicted gene 14409.
Gm14305 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104609Novel KRAB box and zinc finger, C2H2 type domain containing protein.
Zfp973 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104613Novel KRAB box and zinc finger, C2H2 type domain containing protein.
Gm14308 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104618Predicted gene 14308.
Zfp965 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104630Zinc finger protein 965.
Gm2026 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104636Predicted gene 2026.
Gm6710 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104640Predicted gene 14391.
Shroom1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104641Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation.
Gm4724 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104673Predicted gene 4724.
Zfp968 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104675Zinc finger protein 968.
Gm2004 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104677Predicted gene 14419.
Gm14391 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104686Predicted gene 14391.
Gm14399 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104688Predicted gene 14399.
Gm14444 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104698Predicted gene 14444.
Skp1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000104700S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progre [...]
Nelfcd protein networkhttps://string-db.org/network/10090.ENSMUSP00000104703Negative elongation factor D; Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (By similarity). The NELF complex, [...]
Sec24a protein networkhttps://string-db.org/network/10090.ENSMUSP00000104725Protein transport protein Sec24A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main fu [...]
0610009B22Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000104726RIKEN cDNA 0610009B22 gene.
Atmin protein networkhttps://string-db.org/network/10090.ENSMUSP00000104727ATM interactor; Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absen [...]
Fam186b protein networkhttps://string-db.org/network/10090.ENSMUSP00000104728Family with sequence similarity 186, member B.
Cdyl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104730Chromodomain Y-like protein 2.
Hnrnpab protein networkhttps://string-db.org/network/10090.ENSMUSP00000104731Heterogeneous nuclear ribonucleoprotein A/B; Transcriptional repressor. Binds to CArG box motifs, single- stranded and double-stranded DNA, and RNA. It may be that repression by CBF-A is a result [...]
Maf protein networkhttps://string-db.org/network/10090.ENSMUSP00000104732Transcription factor Maf; Acts as a transcriptional activator or repressor. When overexpressed, represses anti-oxidant response element (ARE)-mediated transcription. Involved either as an oncogen [...]
Nudt7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104737Peroxisomal coenzyme A diphosphatase NUDT7; Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3',5'- ADP and the corresp [...]
Zfp354a protein networkhttps://string-db.org/network/10090.ENSMUSP00000104747Zinc finger protein 354A; It may play a role in renal development and may also be involved in the repair of the kidney after ischemia-reperfusion or folic acid administration.
4933414I15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000104751RIKEN cDNA 4933414I15 gene.
Zfp354b protein networkhttps://string-db.org/network/10090.ENSMUSP00000104752Zinc finger protein 354B; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Zfp879 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104762Zinc finger protein 879; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Zfp354c protein networkhttps://string-db.org/network/10090.ENSMUSP00000104763Zinc finger protein 354C; May function as a transcription repressor. Binds to 5'-CCACA- 3' core sequence. Suppresses osteogenic effects of RUNX2. May be involved in osteoblastic differentiation ( [...]
Cass4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104764Cas scaffolding protein family member 4; Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhe [...]
Tshz2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104785Teashirt homolog 2; Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential).
Aida protein networkhttps://string-db.org/network/10090.ENSMUSP00000104795Axin interactor, dorsalization-associated protein; Acts as a ventralizing factor during embryogenesis (By similarity). Inhibits axin-mediated JNK activation by binding axin and disrupting axin ho [...]
Kcng1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104815Potassium voltage-gated channel subfamily G member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulat [...]
Zfp62 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104820Zinc finger protein 62; May play a role in differentiating skeletal muscle.
Ifi47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104825Interferon-gamma-inducible GTPase Ifggc1 protein.
Gm5431 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104833Predicted gene 5431.
Rnf114 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104837E3 ubiquitin-protein ligase RNF114; E3 ubiquitin-protein ligase that promotes the ubiquitination of various substrates. In turn, participates in the regulation of many biological processes includ [...]
B4galt5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104844Beta-1,4-galactosyltransferase 5; Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point [...]
Chst4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104845Carbohydrate sulfotransferase 4; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetyl [...]
Pelo protein networkhttps://string-db.org/network/10090.ENSMUSP00000104849Protein pelota homolog; Required for normal chromosome segregation during cell division and genomic stability. May function in recognizing stalled ribosomes and triggering endonucleolytic cleavag [...]
Med7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104855Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Me [...]
Itk protein networkhttps://string-db.org/network/10090.ENSMUSP00000104860Tyrosine-protein kinase ITK/TSK; Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventiona [...]
Stau1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104861Double-stranded RNA-binding protein Staufen homolog 1; Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the c [...]
Snx18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104864Sorting nexin-18; Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. [...]
Pkd1l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104865Polycystic kidney disease protein 1-like 3; Component of a calcium channel. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution [...]
Cdc20b protein networkhttps://string-db.org/network/10090.ENSMUSP00000104867Cell division cycle 20B.
Sulf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104872Extracellular sulfatase Sulf-2; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specif [...]
Prickle1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104878Prickle-like protein 1; Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure (By similarity). Convergent extension is a comp [...]
Clint1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104884Clathrin interactor 1; Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi networ [...]
Map3k1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104890Mitogen-activated protein kinase kinase kinase 1; Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. May [...]
Zmynd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104892Zinc finger, MYND-type-containing 8.
Mier3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104895Mesoderm induction early response protein 3; Transcriptional repressor.
Slc2a13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104906Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.
Slc35c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104923Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a f [...]
1700025C18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000104927RIKEN cDNA 1700025C18 gene.
Nfatc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104931Nuclear factor of activated T-cells, cytoplasmic 3; Acts as a regulator of transcriptional activation. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the ind [...]
Shank3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104932SH3 and multiple ankyrin repeat domains protein 3; Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse [...]
Cpt1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000104936Carnitine O-palmitoyltransferase 1, muscle isoform.
Nln protein networkhttps://string-db.org/network/10090.ENSMUSP00000104938Neurolysin, mitochondrial; Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A; Belongs to the peptidase M3 family.
Pltp protein networkhttps://string-db.org/network/10090.ENSMUSP00000104939Phospholipid transfer protein; Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylgl [...]
Plxnb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104955Plexin-B2; Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Plays a role in glutamatergic synapse development and is required for SEMA4A- m [...]
Wfdc11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104956Protein WFDC11.
Mrps36 protein networkhttps://string-db.org/network/10090.ENSMUSP0000010495728S ribosomal protein S36, mitochondrial.
Wfdc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104959Protein WFDC9.
Wfdc16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104960WAP four-disulfide core domain 16.
Wfdc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104963WAP four-disulfide core domain protein 8.
Kcnip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104964Kv channel-interacting protein 1; Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate o [...]
Dbndd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104973Dysbindin domain-containing protein 2; May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro) (By similarity); Belongs to the dysbindin family.
Sys1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104976Protein SYS1 homolog; Involved in protein trafficking. May serve as a receptor for ARFRP1 (By similarity).
Tubgcp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104977Gamma-tubulin complex component 6; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
Lrrc36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104979Leucine-rich repeat-containing protein 36.
Slpi protein networkhttps://string-db.org/network/10090.ENSMUSP00000104992Antileukoproteinase; Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. Modulates the innate immune response after bacterial infection. [...]
Ttll8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000104996Protein monoglycylase TTLL8; Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of t [...]
Elmo3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105000Engulfment and cell motility protein 3; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initial [...]
Wfdc15b protein networkhttps://string-db.org/network/10090.ENSMUSP00000105001WAP four-disulfide core domain protein 15B; Antibacterial protein which inhibits the growth of E.coli and S.aureus.
Brd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105007Bromodomain-containing 1.
Pkig protein networkhttps://string-db.org/network/10090.ENSMUSP00000105027cAMP-dependent protein kinase inhibitor gamma; Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme af [...]
Tnpo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105028Transportin-1; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of t [...]
R3hdml protein networkhttps://string-db.org/network/10090.ENSMUSP00000105043Peptidase inhibitor R3HDML; Putative serine protease inhibitor; Belongs to the CRISP family.
Fitm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105045Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Gdap1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105047Ganglioside-induced differentiation-associated protein 1-like 1; Belongs to the GST superfamily.
Ppara protein networkhttps://string-db.org/network/10090.ENSMUSP00000105049Peroxisome proliferator-activated receptor alpha; Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn- glycerol-3- [...]
Arhgef28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105053Rho guanine nucleotide exchange factor 28; Functions as a RHOA-specific guanine nucleotide exchange factor regulating signaling pathways downstream of integrins and growth factor receptors. Funct [...]
Gpr75 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105057Probable G-protein coupled receptor 75; G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosp [...]
Ptprt protein networkhttps://string-db.org/network/10090.ENSMUSP00000105067Receptor-type tyrosine-protein phosphatase T; May be involved in both signal transduction and cellular adhesion in the CNS. May have specific signaling roles in the tyrosine phosphorylation/depho [...]
Lpin3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105082Phosphatidate phosphatase LPIN3; Regulates fatty acid metabolism. Magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during [...]
Top1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105094DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA dup [...]
Mpped1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105096Metallophosphoesterase domain-containing protein 1; May have metallophosphoesterase activity (in vitro).
Ralgapb protein networkhttps://string-db.org/network/10090.ENSMUSP00000105111Ral GTPase-activating protein subunit beta; Non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators for the Ras-like small GTPases RALA and RALB.
Snhg11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105114Small nucleolar RNA host gene 11 (Non-protein coding).
Tcf20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105136Transcription factor 20; Transcriptional activator that binds to the regulatory region of MMP3 and thereby controls stromelysin expression. It stimulates the activity of various transcriptional a [...]
5730522E02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000105137RIKEN cDNA 5730522E02 gene.
Bcl11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000105140B-cell lymphoma/leukemia 11A; May play a role in hematopoiesis. Essential factor in lymphopoiesis, required for B-cell formation in fetal liver. May function as a modulator of the transcriptional [...]
Cyp2d34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105141Cytochrome P450, family 2, subfamily d, polypeptide 34; Belongs to the cytochrome P450 family.
Polr2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000105147DNA-directed RNA polymerase II subunit RPB3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
Vstm2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000105149V-set and transmembrane domain-containing protein 2-like protein.
Atp6ap1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000105168ATPase, H+-transporting, lysosomal accessory protein 1-like.
Vcan protein networkhttps://string-db.org/network/10090.ENSMUSP00000105173Versican core protein; May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiati [...]
Rasa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105179RAS p21 protein activator 1.
Zc3h7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000105181Zinc finger CCCH type-containing 7B.
Ogfod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105183Prolyl 3-hydroxylase OGFOD1; Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro- 62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficienc [...]
Ehbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105191EH domain-binding protein 1; May play a role in actin reorganization. Links clathrin- mediated endocytosis to the actin cytoskeleton. May act as Rab effector protein and play a role in vesicle tr [...]
Mrtfa protein networkhttps://string-db.org/network/10090.ENSMUSP00000105207Myocardin-related transcription factor A; Transcription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoske [...]
Ces1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000105210Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
Scand1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105211SCAN domain-containing 1.
Mctp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105212Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term [...]
Rbm39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105216RNA-binding protein 39; Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1. May be involved in pre- mRNA splicing process; Belongs to the splic [...]
Slc1a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105223Neutral amino acid transporter A; Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence (By similarity); Belongs to the dicarboxylate/amino acid:cation symporter (D [...]
Atf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105234Cyclic AMP-dependent transcription factor ATF-4; Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular [...]
Cpne1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105237Copine-1; Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF- alpha receptor signaling pathway in a calcium-dependen [...]
Fer1l4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105240Fer-1-like protein 4.
Chd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105243Chromodomain-helicase-DNA-binding protein 9; Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has [...]
Cbx7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105245Chromobox protein homolog 7; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, includi [...]
6430550D23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000105246RIKEN cDNA 6430550D23 gene.
Cep250 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105248Centrosome-associated protein CEP250; May be involved in ciliogenesis. Probably plays an important role in centrosome cohesion during interphase.
Apobec3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105249DNA dC->dU-editing enzyme APOBEC-3; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent [...]
Tox3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105250TOX high mobility group box family member 3; Transcriptional coactivator of the p300/CBP-mediated transcription complex. Activates transactivation through cAMP response element (CRE) sites. Prote [...]
Cbx6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105255Chromobox protein homolog 6; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, includi [...]
Uqcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105264Ubiquinol-cytochrome-c reductase complex assembly factor 1; Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b- [...]
Vstm2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000105272V-set and transmembrane domain-containing protein 2A; Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of pre [...]
Zfp423 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105282Zinc finger protein 423; Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associat [...]
Ncoa6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105295Nuclear receptor coactivator 6; Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone- dependent fashion. Coactivates expre [...]
Spata48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105300Spermatogenesis-associated protein 48.
Vwc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105303Brorin; BMP antagonist which may play a role in neural development. Promotes cell adhesion.
Itch protein networkhttps://string-db.org/network/10090.ENSMUSP00000105307E3 ubiquitin-protein ligase Itchy; Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers th [...]
Neto2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105308Neuropilin and tolloid-like protein 2; Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetic [...]
Triobp protein networkhttps://string-db.org/network/10090.ENSMUSP00000105312TRIO and F-actin-binding protein; May regulate actin cytoskeletal organization, cell spreading and cell contraction by directly binding and stabilizing filamentous F- actin. The localized formati [...]
Rapgef5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105313Rap guanine nucleotide exchange factor 5; Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation (By similarity).
Nsun2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105321RNA cytosine C(5)-methyltransferase NSUN2; RNA cytosine C(5)-methyltransferase that methylates cytosine to 5-methylcytosine (m5C) in various RNAs, such as tRNAs, mRNAs and some long non-coding RN [...]
Mta1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105349Metastasis-associated protein MTA1; Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator. As a part of the histone- deacetylase multiprotein complex (Nu [...]
Snta1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105350Alpha-1-syntrophin; Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and t [...]
Cdk5rap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105353CDK5 regulatory subunit-associated protein 1; Probable regulator of CDK5 activity. May inhibit CDK5 function via its interaction with CDK5R1 (By similarity).
Zfp429 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105354Regulator of sex-limitation 2.
Prdx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105356Peroxiredoxin-2; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection agains [...]
Rnaseh2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000105358Ribonuclease H2 subunit A; Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the remova [...]
H2az2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105359Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machiner [...]
Mast1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105363Microtubule-associated serine/threonine-protein kinase 1; Microtubule-associated protein essential for correct brain development. Appears to link the dystrophin/utrophin network with microtubule [...]
Zfp708 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105364Zinc finger protein 708.
Txn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105370Thioredoxin, mitochondrial; Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity; Belongs [...]
Bpifa6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105375BPI fold-containing family A, member 6.
Bpifb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105379BPI fold-containing family B member 4; May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to acc [...]
Rad23a protein networkhttps://string-db.org/network/10090.ENSMUSP00000105383UV excision repair protein RAD23 homolog A; Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent ma [...]
Nfix protein networkhttps://string-db.org/network/10090.ENSMUSP00000105386Nuclear factor 1 X-type; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These [...]
Apol9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000105397Apolipoprotein L 9b.
4930404H24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000105406RIKEN cDNA 4930404H24 gene.
Zmiz2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105409Zinc finger MIZ domain-containing protein 2; Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors.
Asxl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105413Polycomb group protein ASXL1; Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound retinoic acid receptors (RARs) and peroxisome proliferator-acti [...]
Plagl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105419Pleiomorphic adenoma gene-like 2.
Ccm2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000105425Cerebral cavernous malformations 2 protein-like.
Bcl2l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105445Bcl-2-like protein 1; Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and [...]
Cox4i2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105446Cytochrome c oxidase subunit 4 isoform 2, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylatio [...]
Defb45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105460Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
Defb20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105462Beta-defensin 20; Has antibacterial activity; Belongs to the beta-defensin family.
Rbck1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105473RanBP-type and C3HC4-type zinc finger-containing protein 1; E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then tra [...]
Ankrd36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105482Ankyrin repeat domain 36.
Eml1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105486Echinoderm microtubule-associated protein-like 1; Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic s [...]
Fam110a protein networkhttps://string-db.org/network/10090.ENSMUSP00000105491Protein FAM110A; Belongs to the FAM110 family.
Znrf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105493E3 ubiquitin-protein ligase ZNRF3; E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt rec [...]
Snph protein networkhttps://string-db.org/network/10090.ENSMUSP00000105501Syntaphilin; Inhibits SNARE complex formation by absorbing free syntaxin- 1.
Ninl protein networkhttps://string-db.org/network/10090.ENSMUSP00000105522Ninein-like protein; Involved in the microtubule organization in interphase cells. Overexpression induces the fragmentation of the Golgi, and causes lysosomes to disperse toward the cell peripher [...]
Papola protein networkhttps://string-db.org/network/10090.ENSMUSP00000105527Poly(A) polymerase alpha; Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity [...]
Tmed9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105531Transmembrane emp24 domain-containing protein 9; Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport invo [...]
Nf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105536Merlin; Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosi [...]
Nr3c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105539Mineralocorticoid receptor; Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements [...]
Zfp345 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105540Zinc finger protein 345.
Zfp442 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105542Zinc-finger protein in podocyte II.
Syndig1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105560Synapse differentiation-inducing gene protein 1; May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation.
Clmn protein networkhttps://string-db.org/network/10090.ENSMUSP00000105563Calmin.
Gm11032 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105567Predicted gene 11032.
Gm1330 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105568Predicted gene 1330.
Mtmr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105569Myotubularin-related protein 3; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3- phosphate and phosphatidylinositol 3,5-b [...]
Cst8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105573Cystatin-8; Performs a specialized role during sperm development and maturation; Belongs to the cystatin family.
Hormad2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105574HORMA domain-containing protein 2; Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid- pachytene checkpoint and the [...]
Cstl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105581Cystatin-like 1; Belongs to the cystatin family.
Serpina3j protein networkhttps://string-db.org/network/10090.ENSMUSP00000105583Serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3J; Belongs to the serpin family.
Serpina3i protein networkhttps://string-db.org/network/10090.ENSMUSP00000105584Serine (or cysteine) peptidase inhibitor, clade A, member 3I; Belongs to the serpin family.
Nxt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105587NTF2-related export protein 1; Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved [...]
Sstr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105588Somatostatin receptor type 4; Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibit [...]
Foxa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105590Hepatocyte nuclear factor 3-beta; Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentia [...]
Zfp707 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105592Zinc finger protein 707.
Pax1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105594Paired box protein Pax-1; This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal developm [...]
Eef1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000105602Elongation factor 1-delta; [Isoform 1]: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs [...]
Ralgapa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105613Ral GTPase-activating protein subunit alpha-2; Catalytic subunit of the heterodimeric RalGAP2 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB.
Tcn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105620Transcobalamin-2; Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells.
Zfp961 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105623Zinc finger protein 961.
Ddx24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105628ATP-dependent RNA helicase DDX24; ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
Zfp882 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105629Zinc finger protein 882.
Snx5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105657Sorting nexin-5; Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol lipids. Acts in part as component of the retromer membrane-defor [...]
Ptk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105663Focal adhesion kinase 1; Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation a [...]
Use1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105680Vesicle transport protein USE1; SNARE that may be involved in targeting and fusion of Golgi- derived retrograde transport vesicles with the ER; Belongs to the USE1 family.
Flrt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105684Leucine-rich repeat transmembrane protein FLRT3; Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. [...]
Macrod2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105691ADP-ribose glycohydrolase MACROD2; Removes ADP-ribose from asparatate and glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Dea [...]
Gpr68 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105693Ovarian cancer G-protein coupled receptor 1; Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. M [...]
Kcnn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105705Small conductance calcium-activated potassium channel protein 1; Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolariza [...]
Fgd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105714FYVE, RhoGEF and PH domain-containing protein 3; Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for fre [...]
Mkks protein networkhttps://string-db.org/network/10090.ENSMUSP00000105716McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin; Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis (By similarity). Plays a role in the assembly of [...]
Rab3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000105719Ras-related protein Rab-3A; Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the [...]
Pde4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000105722cAMP-specific 3',5'-cyclic phosphodiesterase 4C; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes; Belongs to the cyclic nucleotide phospho [...]
Gm21961 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105727Predicted gene, 21961.
Zc3h14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105732Zinc finger CCCH domain-containing protein 14; Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
Plcb4 protein networkhttps://string-db.org/network/10090.ENSMUSP000001057361-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated ph [...]
Plcb1 protein networkhttps://string-db.org/network/10090.ENSMUSP000001057431-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activ [...]
Homer3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105751Homer protein homolog 3; Postsynaptic density scaffolding protein. Binds and cross- links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 [...]
Gsdmc protein networkhttps://string-db.org/network/10090.ENSMUSP00000105752Gasdermin-C; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family.
Slc25a42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105754Mitochondrial coenzyme A transporter SLC25A42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and [...]
Shld1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105759Shieldin complex subunit 1; Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex f [...]
Gpcpd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105769Glycerophosphocholine phosphodiesterase GPCPD1; May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activit [...]
Gm2042 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105772Predicted gene 2042.
Mef2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000105773Myocyte-specific enhancer factor 2B; Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription [...]
Gm2016 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105774Predicted gene 2016; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ri [...]
BB287469 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105776Expressed sequence BB287469; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to [...]
Gm8300 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105780Predicted pseudogene 8332; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 4 [...]
Tatdn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105783Putative deoxyribonuclease TATDN1; Putative deoxyribonuclease; Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
Tm6sf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105788Transmembrane 6 superfamily member 2; Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content. May function as sterol isomerase; Belongs to the TM6S [...]
Tmem230 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105793Transmembrane protein 230; Involved in trafficking and recycling of synaptic vesicles.
Ndufa13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105796NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involve [...]
Zhx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105797Zinc fingers and homeoboxes protein 1; Acts as a transcriptional repressor. Increases DNMT3B- mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule betwee [...]
Prnd protein networkhttps://string-db.org/network/10090.ENSMUSP00000105801Prion-like protein doppel; Required for normal acrosome reaction and for normal male fertility. Can bind Cu(2+) (By similarity).
Ngb protein networkhttps://string-db.org/network/10090.ENSMUSP00000105806Neuroglobin; Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell [...]
Smox protein networkhttps://string-db.org/network/10090.ENSMUSP00000105815Spermine oxidase; Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isof [...]
Gcnt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105820N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase; Branching enzyme that converts linear into branched poly-N- acetyllactosaminoglycans. Introduces the blood group I antigen during [...]
Tfap2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000105822Transcription factor AP-2-alpha; Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors [...]
Slc22a22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105825Solute carrier family 22 member 22; Sodium-independent organic anion transporter which exhibits high specificity for a subset of prostaglandins including prostaglandin E2 (PGE2), prostaglandin E1 [...]
Mavs protein networkhttps://string-db.org/network/10090.ENSMUSP00000105828Mitochondrial antiviral-signaling protein; Required for innate immune defense against viruses. Acts downstream of DHX33, DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced duri [...]
Esrrb protein networkhttps://string-db.org/network/10090.ENSMUSP00000105833Steroid hormone receptor ERR2; Transcription factor that binds a canonical ESRRB recognition (ERRE) sequence 5'TCAAGGTCA-3' localized on promoter and enhancer of targets genes regulating their ex [...]
Gm6871 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105843Predicted gene 6871.
Spef1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105847Sperm flagellar protein 1; Microtubule-associated protein that promotes microtubule bundling and stabilizes microtubules against depolymerization in response to cold shock. Microtubule-associated [...]
Col14a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105850Collagen alpha-1(XIV) chain; Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then [...]
Adam33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105861Disintegrin and metalloproteinase domain-containing protein 33.
Cage1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105862Cancer-associated gene 1 protein homolog.
Ints10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105871Integrator complex subunit 10; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. Th [...]
Ltbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105883Latent-transforming growth factor beta-binding protein 2; May play an integral structural role in elastic-fiber architectural organization and/or assembly. Belongs to the LTBP family.
Serpinb6e protein networkhttps://string-db.org/network/10090.ENSMUSP00000105904Serine (or cysteine) peptidase inhibitor, clade B, member 6e; Belongs to the serpin family.
Coq6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105905Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-poly [...]
Ebf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105915Transcription factor COE4; Seems to weakly activate transcription. Binds an Olf-1 consensus site in vitro; Belongs to the COE family.
Serpinb6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000105922Serine (Or cysteine) peptidase inhibitor, clade B, member 6B; Belongs to the serpin family.
Elmsan1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105923ELM2 and Myb/SANT-like domain-containing 1.
Oxr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105926Oxidation resistance protein 1; May be involved in protection from oxidative damage; Belongs to the OXR1 family.
Tgm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105928Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain; Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various prot [...]
Zc3h6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105949Zinc finger CCCH domain-containing protein 6.
Fbln7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105953Fibulin-7; An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as i [...]
Tmem87b protein networkhttps://string-db.org/network/10090.ENSMUSP00000105954Transmembrane protein 87B; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN).
Bcl2l11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105970Bcl-2-like protein 11; Induces apoptosis and anoikis. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent; Belongs to the Bcl-2 fami [...]
Smoc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105976SPARC-related modular calcium-binding protein 1; Probable regulator of osteoblast differentiation. Plays essential roles in both eye and limb development.
Prl8a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105979Prolactin-8A8; Belongs to the somatotropin/prolactin family.
Srsf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105980Serine/arginine-rich splicing factor 5; May be required for progression through G1 and entry into S phase of cell growth. May play a regulatory role in pre-mRNA splicing. Autoregulates its own ex [...]
Prl8a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105984Prolactin-8A6; Belongs to the somatotropin/prolactin family.
Zfp661 protein networkhttps://string-db.org/network/10090.ENSMUSP00000105995Zinc finger protein 2; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Prl protein networkhttps://string-db.org/network/10090.ENSMUSP00000105998Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.
Stard7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106004StAR-related lipid transfer protein 7, mitochondrial; May play a protective role in mucosal tissues by preventing exaggerated allergic responses.
Lrp2bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000106010LRP2-binding protein; May act as an adapter that regulates LRP2 function.
Ripor2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106013Rho family-interacting cell polarization regulator 2; Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte [...]
Rpl30 protein networkhttps://string-db.org/network/10090.ENSMUSP0000010601460S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family.
Itpripl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106016Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1.
Ncaph protein networkhttps://string-db.org/network/10090.ENSMUSP00000106017Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex p [...]
Gphn protein networkhttps://string-db.org/network/10090.ENSMUSP00000106018Molybdopterin molybdenumtransferase; Microtubule-associated protein involved in membrane protein- cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subs [...]
Cmah protein networkhttps://string-db.org/network/10090.ENSMUSP00000106021Cytidine monophosphate-N-acetylneuraminic acid hydroxylase; Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell- pathogen inte [...]
Max protein networkhttps://string-db.org/network/10090.ENSMUSP00000106025Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcrip [...]
Ropn1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000106038Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermato [...]
Adam34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106041A disintegrin and metallopeptidase domain 34.
Usp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106046Ubiquitin carboxyl-terminal hydrolase 8; Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventi [...]
Gabpb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106055GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes.
Btn2a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106063Butyrophilin subfamily 2 member A2; Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Fam227b protein networkhttps://string-db.org/network/10090.ENSMUSP00000106076Protein FAM227B; Belongs to the FAM227 family.
H2bc11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106082H2B clustered histone 11.
H2bc12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106085Histone H2B type 1-K; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
Myo10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106087Unconventional myosin-X; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles an [...]
Cops2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106090COP9 signalosome complex subunit 2; Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential [...]
Hist1h2bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000106099Histone H2B type 1-P; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
Zscan26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106111Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation.
Gpx5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106117Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glut [...]
Prag1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106118Inactive tyrosine-protein kinase PRAG1; Catalytically inactive protein kinase that acts as a scaffold protein (By similarity). Functions as an effector of the small GTPase RND2, which stimulates [...]
Wdr95 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106128WD40 repeat domain 95.
Sqor protein networkhttps://string-db.org/network/10090.ENSMUSP00000106133Sulfide:quinone oxidoreductase, mitochondrial; Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone, giving rise to thiosulfate and ultimately to sulfane (mo [...]
Gli3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106137Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 [...]
Hecw1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106145E3 ubiquitin-protein ligase HECW1; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1.
Slc28a2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000106150Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
Trim9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106151E3 ubiquitin-protein ligase TRIM9; E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation [...]
C1qtnf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106152Complement C1q tumor necrosis factor-related protein 3.
Slc28a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106154Sodium/nucleoside cotransporter 2; Sodium-dependent and purine-selective. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purin [...]
Shf protein networkhttps://string-db.org/network/10090.ENSMUSP00000106160SH2 domain-containing adapter protein F; Adapter protein which may play a role in the regulation of apoptosis in response to PDGF.
Arid4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000106163AT-rich interactive domain-containing protein 4B; Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating inte [...]
Duoxa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106166Dual oxidase maturation factor 1; May be required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX1.
Sord protein networkhttps://string-db.org/network/10090.ENSMUSP00000106180Sorbitol dehydrogenase; Polyol dehydrogenase that catalyzes the reversible NAD(+)- dependent oxidation of various sugar alcohols (By similarity). Is active with D-sorbitol (D-glucitol) leading to [...]
Lyst protein networkhttps://string-db.org/network/10090.ENSMUSP00000106188Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules.
Map4k5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106199Mitogen-activated protein kinase kinase kinase kinase 5; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway (By similarity).
LOC108168681 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106205Predicted gene 6509.
Prl2c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106224Prolactin-2C2; May have a role in embryonic development. It is likely to provide a growth stimulus to target cells in maternal and fetal tissues during the development of the embryo at mid-gestat [...]
Gm3404 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106226Predicted gene 3404.
Wdr76 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106232WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
Gm6370 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106241Predicted gene 6370.
Hypk protein networkhttps://string-db.org/network/10090.ENSMUSP00000106242Huntingtin-interacting protein K; Has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. Protects against HTT polyQ-mediated apoptosis in neuronal cells (By similarity [...]
Cplane1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106247Ciliogenesis and planar polarity effector 1; Involved in ciliogenesis. Involved in the establishment of cell polarity required for directional cell migration. Proposed to act in association with [...]
Rpl36al protein networkhttps://string-db.org/network/10090.ENSMUSP0000010624960S ribosomal protein L36a.
Lrr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106251Leucine-rich repeat protein 1.
Zmynd11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106268Zinc finger MYND domain-containing protein 11; Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongati [...]
Trp53bp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106278TP53-binding protein 1; Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis. Plays a key ro [...]
Zscan29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106289Zinc finger SCAN domains 29.
Kpna7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106301Importin subunit alpha-8; Functions in nuclear protein import.
Lcmt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106302tRNA wybutosine-synthesizing protein 4; Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modifie [...]
Tgm7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106303Transglutaminase 7.
C7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106317Complement component 7.
Oxct1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106318Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA interm [...]
Cdan1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106329Codanin-1; May act as a negative regulator of ASF1 in chromatin assembly.
Srp54b protein networkhttps://string-db.org/network/10090.ENSMUSP00000106336Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating me [...]
Ankrd61 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106345Ankyrin repeat domain-containing protein 61.
Nek3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106358Serine/threonine-protein kinase Nek3; Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contribute [...]
Kdelr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106359ER lumen protein-retaining receptor 2; Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Gol [...]
Grid2ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000106361Delphilin; Postsynaptic scaffolding protein at the Purkinje cell synapse, where it may serve to link GRID2 with actin cytoskeleton and various signaling molecules.
Fam90a1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000106369Family with sequence similarity 90, member A1A.
Gm43517 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106374Predicted gene 43517.
Defa43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106377Defensin, alpha, 42.
Defa42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106380Defensin, alpha, 42.
Defa41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106382Defensin, alpha, 41.
AY761185 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106386cDNA sequence AY761185.
Defb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106391Beta-defensin 5; Has antibacterial activity; Belongs to the beta-defensin family.
Mga protein networkhttps://string-db.org/network/10090.ENSMUSP00000106401MAX gene-associated protein; Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an acti [...]
Rpap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106420RNA polymerase II-associated protein 1; Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to r [...]
Erich1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106436Glutamate-rich 1.
Spint1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106441Kunitz-type protease inhibitor 1; Inhibitor of HGF activator.
Hdac9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106443Histone deacetylase 9; Devoided of intrinsic deacetylase activity, promotes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) by recruiting HD [...]
Ppp1r14d protein networkhttps://string-db.org/network/10090.ENSMUSP00000106444Protein phosphatase 1 regulatory subunit 14D; Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1C [...]
Mafk protein networkhttps://string-db.org/network/10090.ENSMUSP00000106460Transcription factor MafK; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (By similarity). However, the [...]
Lpgat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106480Acyl-CoA:lysophosphatidylglycerol acyltransferase 1; Lysophosphatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear pref [...]
Dld protein networkhttps://string-db.org/network/10090.ENSMUSP00000106481Dihydrolipoyl dehydrogenase, mitochondrial; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruv [...]
Adap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106489ArfGAP with dual PH domains 1.
Mcf2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000106500Guanine nucleotide exchange factor DBS; Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC4 [...]
Acp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106509Low molecular weight phosphotyrosine protein phosphatase; Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
Tatdn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106518Putative deoxyribonuclease TATDN3; Putative deoxyribonuclease; Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
Tpt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106519Translationally-controlled tumor protein; Involved in calcium binding and microtubule stabilization.
Zfp68 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106530KRAB-containing zinc-finger protein KRAZ2.
Arhgef7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106534Rho guanine nucleotide exchange factor 7; Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. May function as a positive regulator of apoptosis. Functions in [...]
Cnpy4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106559Protein canopy homolog 4; Plays a role in the regulation of the cell surface expression of TLR4; Belongs to the canopy family.
Taf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106561Transcription initiation factor TFIID subunit 6; TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is mu [...]
Mboat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106567Lysophospholipid acyltransferase 2; Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-gl [...]
Zscan21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106584Zinc finger and SCAN domain-containing protein 21; Strong transcriptional activator. Associated with meiosis in both male and female gametogenesis. May have different functions in somatic cells; [...]
Fam155a protein networkhttps://string-db.org/network/10090.ENSMUSP00000106596Transmembrane protein FAM155A; Belongs to the FAM155 family.
Pilrb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106606Paired immunoglobulin-like type 2 receptor beta; Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PIL [...]
Dmtn protein networkhttps://string-db.org/network/10090.ENSMUSP00000106612Dematin; Membrane-cytoskeleton-associated protein with F-actin-binding activity that induces F-actin bundles formation and stabilization. Its F-actin-bundling activity is reversibly regulated upo [...]
Tgfbr3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000106621Transforming growth factor, beta receptor III-like.
Tlr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106625Toll-like receptor 5; Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response. Recognizes small molecular m [...]
Muc15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106645Mucin-15.
Pop7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106664Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclea [...]
Epo protein networkhttps://string-db.org/network/10090.ENSMUSP00000106667Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR lea [...]
Ephb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106684Ephrin type-B receptor 4; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling [...]
Mpped2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106692Metallophosphoesterase MPPED2; Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system. Belongs to the UPF0046 family.
Ntsr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106693Neurotensin receptor type 2; Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-p [...]
Ap1s1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106709AP-1 complex subunit sigma-1A; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP c [...]
Znhit1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106720Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction (By similarity). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription [...]
Cldn15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106722Claudin-15; Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members function as impermeable barriers [...]
Gnrh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106724Prolactin release-inhibiting factor 1; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Belongs to the GnRH family.
Psen2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106735Presenilin-2 CTF subunit; Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch [...]
Ccdc73 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106743Coiled-coil domain-containing protein 73.
Cdc42bpa protein networkhttps://string-db.org/network/10090.ENSMUSP00000106746Serine/threonine-protein kinase MRCK alpha; Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization an [...]
Tcp11l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106747T-complex protein 11-like protein 1; Belongs to the TCP11 family.
D430041D05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000106756RIKEN cDNA D430041D05 gene.
Lmo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106770Rhombotin-2; Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.
Dtx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106772Probable E3 ubiquitin-protein ligase DTX2; Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Prob [...]
Ssc4d protein networkhttps://string-db.org/network/10090.ENSMUSP00000106782Scavenger receptor cysteine-rich domain-containing group B protein.
Akt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106789RAC-gamma serine/threonine-protein kinase; AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes includi [...]
Pom121 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106801Nuclear envelope pore membrane protein POM 121; Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to [...]
Efr3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000106809Protein EFR3 homolog B; Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphat [...]
Defb30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106838Beta-defensin 30; Has antibacterial activity; Belongs to the beta-defensin family.
Ifi204 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106845Interferon-activable protein 204; Inhibits the transcription of ribosomal RNA. May inhibit DNA binding by UBTF. Inhibits cell growth via p53/TP53 and RB1-dependent and independent pathways. Acts [...]
Cadm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106851Cell adhesion molecule 3; Involved in the cell-cell adhesion. Has both calcium- independent homophilic cell-cell adhesion activity and calcium- independent heterophilic cell-cell adhesion activit [...]
Mptx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106855Pentaxin.
Tagln2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106861Transgelin-2; Belongs to the calponin family.
B230118H07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000106862Protein C11orf74 homolog; Seems to play a role in ciliary BBSome localization, maybe through interaction with IFT-A complex.
Tnfrsf19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106865Tumor necrosis factor receptor superfamily member 19; Can mediate activation of c-Jun and NF-kappa-B. May promote caspase-independent cell death (By similarity). Isoform 2 and isoform 3 may act a [...]
Igsf9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106866Protein turtle homolog A; Functions in dendrite outgrowth and synapse maturation.
Ttc17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106869Tetratricopeptide repeat protein 17; Plays a role in primary ciliogenesis by modulating actin polymerization; Belongs to the TTC17 family.
Atp1a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106874Sodium/potassium-transporting ATPase subunit alpha-4; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium [...]
Accs protein networkhttps://string-db.org/network/10090.ENSMUSP000001068771-aminocyclopropane-1-carboxylate synthase-like protein 1; Does not catalyze the synthesis of 1-aminocyclopropane-1- carboxylate but is capable of catalyzing the deamination of L- vinylglycine; B [...]
Vangl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106894Vang-like protein 2; Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar c [...]
Tspan18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106896Tetraspanin-18.
Trp53i11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106897Tumor protein p53-inducible protein 11.
Prdm11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106905PR domain-containing protein 11; May be involved in transcription regulation. Belongs to the class V-like SAM-binding methyltransferase superfamily.
Nit1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106926Deaminated glutathione amidase; Catalyzes the hydrolysis of the amide bond in N-(4- oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmf [...]
Dedd protein networkhttps://string-db.org/network/10090.ENSMUSP00000106931Death effector domain-containing protein; A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating [...]
Dgkz protein networkhttps://string-db.org/network/10090.ENSMUSP00000106934Diacylglycerol kinase zeta; Displays a strong preference for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. R [...]
Usp21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106936Ubiquitin carboxyl-terminal hydrolase 21; Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A r [...]
B4galt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106945Beta-1,4-galactosyltransferase 3; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the [...]
Apoa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106953Proapolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism; Belongs to the apolipoprotein A2 family.
Sdr39u1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106957Epimerase family protein SDR39U1; Putative NADP-dependent oxidoreductase.
Arhgap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106963Rho GTPase-activating protein 1; GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate (By si [...]
Pcp4l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106964Purkinje cell protein 4-like protein 1; Belongs to the PCP4 family.
Sdhc protein networkhttps://string-db.org/network/10090.ENSMUSP00000106968Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport [...]
Ckap5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106970Cytoskeleton-associated protein 5; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as processive microtubule polymerase. Promotes cytop [...]
Ran protein networkhttps://string-db.org/network/10090.ENSMUSP00000106975GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplas [...]
Pacsin3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106981Protein kinase C and casein kinase II substrate protein 3; Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/ [...]
Uap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106983UDP-N-acetylgalactosamine pyrophosphorylase; Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, [...]
Nr1h3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106988Oxysterols receptor LXR-alpha; Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity. Interaction with retinoic acid receptor (RXR) shifts RXR from its role as a s [...]
LOC100041057 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106991RIKEN cDNA C130026I21 gene.
Nuf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000106999Kinetochore protein Nuf2; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kin [...]
Ildr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107047Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways.
Zfp664 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107048Zinc finger protein 664; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Creg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107060Protein CREG1; May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. [...]
Mpzl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107062Myelin protein zero-like protein 1; Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP [...]
Slc39a13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107063Zinc transporter ZIP13; Acts as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family.
Ccr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107069C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellula [...]
Celf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107079CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability [...]
Snrnp35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107080U11/U12 small nuclear ribonucleoprotein 35 kDa protein.
Kbtbd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107089Kelch repeat and BTB domain-containing protein 4.
C1qtnf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107091Complement C1q tumor necrosis factor-related protein 4; May be involved in the regulation of the inflammatory network. The role as pro- or anti-inflammatory seems to be context dependent (By simi [...]
Olfr1262 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107133Olfactory receptor.
Olfr1260 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107137Olfactory receptor.
Olfr1257 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107144Olfactory receptor.
Olfr1254 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107148Olfactory receptor.
Fmo4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107150Dimethylaniline monooxygenase [N-oxide-forming] 4; This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides; Belongs to the FMO family.
Olfr1247 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107157Olfactory receptor.
Amn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107160Antagonist of mitotic exit network 1.
Dennd5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000107182DENN domain-containing protein 5B; Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab protein [...]
Clip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107192CAP-Gly domain-containing linker protein 1; Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. [...]
Caprin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107195Caprin-2; Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway (By similarity). Facilitates constitutive LRP6 phosphorylation [...]
Pramel6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107198Preferentially-expressed antigen in melanoma-like 6.
Olfr1098 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107200Olfactory receptor.
Olfr1097 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107202Olfactory receptor.
Afap1l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107210Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity).
Diablo protein networkhttps://string-db.org/network/10090.ENSMUSP00000107214Diablo homolog, mitochondrial; Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins [...]
Lrrc55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107228Leucine-rich repeat-containing protein 55; Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marke [...]
Rpgrip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107230X-linked retinitis pigmentosa GTPase regulator-interacting protein 1; May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Re [...]
Tdrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107231Tudor domain-containing protein 1; Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for t [...]
Tnks1bp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107232182 kDa tankyrase-1-binding protein.
Hnrnpc protein networkhttps://string-db.org/network/10090.ENSMUSP00000107237Heterogeneous nuclear ribonucleoproteins C1/C2; Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the st [...]
Klhl20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107238Kelch-like protein 20; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response and anterograde Golgi to endosome transport. The BCR [...]
Cenpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000107245Centromere protein L; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chr [...]
Ppfibp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107250Liprin-beta-1; May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A (By similarity). Belongs to the liprin family. Liprin-beta subfamily.
Xirp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107262Xin actin-binding repeat-containing protein 1; Protects actin filaments from depolymerization.
Arntl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107266Aryl hydrocarbon receptor nuclear translocator-like protein 2; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, [...]
Tcf7l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107284Transcription factor 7-like 2; Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of [...]
Fgfr1op2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107292FGFR1 oncogene partner 2 homolog; May be involved in wound healing pathway.
Tmx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107294Thioredoxin-related transmembrane protein 2.
Camkk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107297Calcium/calmodulin-dependent protein kinase kinase 2; Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular proc [...]
Rassf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107333Ras association domain-containing protein 8.
Lmntd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107337Lamin tail domain-containing protein 1; Belongs to the intermediate filament family.
Tfpi protein networkhttps://string-db.org/network/10090.ENSMUSP00000107347Tissue factor pathway inhibitor; Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It [...]
Tmem260 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107364Transmembrane protein 260; Belongs to the TMEM260 family.
Tctn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107367Tectonic-1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between t [...]
Myl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107380Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function. Following phosphorylation, plays a role in cross-brid [...]
Cux2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107381Homeobox protein cut-like 2; Transcription factor involved in the control of neuronal proliferation and differentiation in the brain. Regulates dendrite development and branching, dendritic spine [...]
Tor1aip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107387Torsin-1A-interacting protein 2; Required for endoplasmic reticulum integrity. Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope as well as induces TO [...]
Nckap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107390Nck-associated protein 1; Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Act [...]
Itprid2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107415Protein ITPRID2.
Recql protein networkhttps://string-db.org/network/10090.ENSMUSP00000107434ATP-dependent DNA helicase Q1; Isoform alpha is a DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Isoform beta may have important ro [...]
Neurl1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000107439E3 ubiquitin-protein ligase NEURL1; Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulat [...]
Calhm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107444Calcium homeostasis modulator protein 1; Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP, required for sensory perception of sweet, bitter an [...]
Trim71 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107447E3 ubiquitin-protein ligase TRIM71; E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miR [...]
Gmfb protein networkhttps://string-db.org/network/10090.ENSMUSP00000107448Glia maturation factor beta; This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells; Belongs to the actin-binding p [...]
Tmppe protein networkhttps://string-db.org/network/10090.ENSMUSP00000107451Transmembrane protein with metallophosphoesterase domain.
Gm15217 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107457Predicted gene 15217.
Slco1a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107458Solute carrier organic anion transporter family member 1A6; May mediate the Na(+)-independent transport of organic anions; Belongs to the organo anion transporter (TC 2.A.60) family.
Ttn protein networkhttps://string-db.org/network/10090.ENSMUSP00000107477Titin; Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forc [...]
Pdcd6ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000107492Programmed cell death 6-interacting protein; Multifunctional protein involved in endocytosis, multivesicular body biogenesis, membrane repair, cytokinesis, apoptosis and maintenance of tight junc [...]
Sufu protein networkhttps://string-db.org/network/10090.ENSMUSP00000107498Suppressor of fused homolog; Negative regulator in the hedgehog/smoothened signaling pathway. Down-regulates GLI1- mediated transactivation of target genes. Part of a corepressor complex that act [...]
Pik3c2g protein networkhttps://string-db.org/network/10090.ENSMUSP00000107499Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that [...]
Gm3543 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107501Predicted gene 3543.
Arpp21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107503cAMP-regulated phosphoprotein 21; Isoform 2 may act as a competitive inhibitor of calmodulin- dependent enzymes such as calcineurin in neurons.
Dclk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107510Serine/threonine-protein kinase DCLK3.
Nfkb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107512Nuclear factor NF-kappa-B p100 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are in [...]
Ccrl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107519C-C chemokine receptor-like 2; Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine- triggered immune responses by capt [...]
Pprc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107530Peroxisome proliferator-activated receptor gamma coactivator-related protein 1; Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and ce [...]
Mmrn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107539Multimerin-2; Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA.
Odr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107544Protein odr-4 homolog; May play a role in the trafficking of a subset of G-protein coupled receptors; Belongs to the ODR-4 family.
Fam234b protein networkhttps://string-db.org/network/10090.ENSMUSP00000107546Protein FAM234B; Belongs to the FAM234 family.
Shld2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107548Shieldin complex subunit 2; Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex f [...]
Plekha3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107551Pleckstrin homology domain-containing family A member 3; Involved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4- phosphate [...]
Rgs13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107572Regulator of G-protein signaling 13; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to b [...]
Kazald1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107579Kazal-type serine protease inhibitor domain-containing protein 1; Involved in the proliferation of osteoblasts during bone formation and bone regeneration. Promotes matrix assembly.
Arhgap22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107587Rho GTPase-activating protein 22; Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a [...]
Hnrnpa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107595Heterogeneous nuclear ribonucleoprotein A3; Plays a role in cytoplasmic trafficking of RNA. Binds to the cis-acting response element, A2RE. May be involved in pre-mRNA splicing (By similarity).
Vsig10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107598V-set and immunoglobulin domain-containing protein 10.
Cfh protein networkhttps://string-db.org/network/10090.ENSMUSP00000107607Complement factor H; Glycoprotein that plays an essential role in maintaining a well-balanced immune response by modulating complement activation. Acts as a soluble inhibitor of complement, where [...]
Taok3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107609Serine/threonine-protein kinase TAO3; Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator o [...]
Hoxd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107614Homeobox protein Hox-D3; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Gm4788 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107620Predicted gene 4788.
Atp5g3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107627ATP synthase F(0) complex subunit C3, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the [...]
Tmem233 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107628Transmembrane protein 233.
Klra3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107629Killer cell lectin-like receptor 3; Receptor on natural killer (NK) cells for class I MHC.
Klra7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107644Killer cell lectin-like receptor 7; Receptor on natural killer (NK) cells for class I MHC.
Klra10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107651Killer cell lectin-like receptor subfamily A, member 10.
Camp protein networkhttps://string-db.org/network/10090.ENSMUSP00000107653Cathelin-related antimicrobial peptide; Acts as a potent antimicrobial peptide.
Chn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107655N-chimaerin; GTPase-activating protein for p21-rac and a phorbol ester receptor. May play an important role in neuronal signal-transduction mechanisms (By similarity). Involved in the assembly of [...]
Lhx9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107657LIM/homeobox protein Lhx9; Involved in gonadal development.
Colq protein networkhttps://string-db.org/network/10090.ENSMUSP00000107658Acetylcholinesterase collagenic tail peptide; Anchors the catalytic subunits of asymmetric AChE to the synaptic basal lamina.
Klra9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107663Killer cell lectin-like receptor subfamily A, member 9.
Fbxw28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107670F-box and WD-40 domain protein 28.
Zfp281 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107677Zinc finger protein 281; Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepres [...]
Cutc protein networkhttps://string-db.org/network/10090.ENSMUSP00000107678Copper homeostasis protein cutC homolog; May play a role in copper homeostasis. Can bind one Cu(1+) per subunit (By similarity).
Klrc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107688Killer cell lectin-like receptor subfamily C, member 2.
Shisa5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107690Protein shisa-5; Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.
Klrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107694Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
Cacna1s protein networkhttps://string-db.org/network/10090.ENSMUSP00000107695Voltage-dependent L-type calcium channel subunit alpha-1S; Pore-forming, alpha-1S subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Calci [...]
Sirt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107697NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and b [...]
Col7a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107701Collagen alpha-1(VII) chain; Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence [...]
Rnf10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107726RING finger protein 10; Transcriptional factor involved in the regulation of MAG (Myelin-associated glycoprotein) expression and myelin formation in Schwann cells; Belongs to the RNF10 family.
Pbrm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107727Protein polybromo-1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/S [...]
Itga6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107729Integrin alpha-6 heavy chain; Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-eg [...]
Mid1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107733E3 ubiquitin-protein ligase Midline-1; Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphat [...]
Klrb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107738Killer cell lectin-like receptor subfamily B member 1.
Cabp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107741Calcium-binding protein 1; Modulates calcium-dependent activity of inositol 1,4,5- triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation [...]
Hccs protein networkhttps://string-db.org/network/10090.ENSMUSP00000107743Cytochrome c-type heme lyase; Links covalently the heme group to the apoprotein of cytochrome c.
Mlec protein networkhttps://string-db.org/network/10090.ENSMUSP00000107749Malectin; Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N- glycosylation (By similarity); Belongs to the malectin f [...]
Pzp protein networkhttps://string-db.org/network/10090.ENSMUSP00000107760Alpha-2-macroglobulin 165 kDa subunit; Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which cont [...]
Msl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107765Male-specific lethal 3 homolog; Has a role in chromatin remodeling and transcriptional regulation. Has a role in X inactivation. Component of the MSL complex which is responsible for the majority [...]
Dync1i2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107768Cytoplasmic dynein 1 intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargo [...]
Oasl1 protein networkhttps://string-db.org/network/10090.ENSMUSP000001077712'-5'-oligoadenylate synthase-like protein 1; Does not have 2'-5'-OAS activity, but can bind double- stranded RNA. Displays antiviral activity via an alternative antiviral pathway independent of [...]
Frmpd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107773FERM and PDZ domain-containing protein 4; Positive regulator of dendritic spine morphogenesis and density. Required for the maintenance of excitatory synaptic transmission. Binds phosphatidylinos [...]
Rhno1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107779RAD9, HUS1, RAD1-interacting nuclear orphan protein 1; Plays a role in DNA damage response (DDR) signaling upon genotoxic stresses such as ionizing radiation (IR) during the S phase. Recruited to [...]
Tlr7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107787Toll-like receptor 7; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific [...]
Tlr8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107793Toll-like receptor 8; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific [...]
Tmsb4x protein networkhttps://string-db.org/network/10090.ENSMUSP00000107795Hematopoietic system regulatory peptide; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerizat [...]
Tspan9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107796Tetraspanin-9; Belongs to the tetraspanin (TM4SF) family.
Mettl8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107804mRNA N(3)-methylcytidine methyltransferase METTL8; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of mRNAs. [Isoform 4]: Stimulates adipogenes [...]
Tceanc protein networkhttps://string-db.org/network/10090.ENSMUSP00000107806Transcription elongation factor A N-terminal and central domain-containing protein.
Prkcd protein networkhttps://string-db.org/network/10090.ENSMUSP00000107830Protein kinase C delta type regulatory subunit; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death a [...]
Rad51ap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107841RAD51-associated protein 1; May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double- strand break repair. Functionally cooper [...]
Gpm6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000107848Neuronal membrane glycoprotein M6-b; May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; th [...]
Adipor1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107856Adiponectin receptor protein 1; Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal glucose and fat homeostasis and f [...]
Foxn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107857Forkhead box N2.
Mvk protein networkhttps://string-db.org/network/10090.ENSMUSP00000107858Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kin [...]
Ntf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107863Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons.
Cacna1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000107869Voltage-dependent L-type calcium channel subunit alpha-1D; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of c [...]
Vwf protein networkhttps://string-db.org/network/10090.ENSMUSP00000107873Von Willebrand antigen 2; Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial colla [...]
Piga protein networkhttps://string-db.org/network/10090.ENSMUSP00000107874N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein; Necessary for the synthesis of N-acetylglucosaminyl- phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis; [...]
Bmx protein networkhttps://string-db.org/network/10090.ENSMUSP00000107884Cytoplasmic tyrosine-protein kinase BMX; Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganiza [...]
Selenok protein networkhttps://string-db.org/network/10090.ENSMUSP00000107887Selenoprotein K; Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration. Involved in endoplasmic reticulum-associated degradation [...]
Ace2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107890Processed angiotensin-converting enzyme 2; Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator (B [...]
Cltrn protein networkhttps://string-db.org/network/10090.ENSMUSP00000107899Collectrin; Plays an important role in amino acid transport by acting as binding partner of amino acid transporters SLC6A18 and SLC6A19, regulating their trafficking on the cell surface and their [...]
Zrsr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107908U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2; Pre-mRNA-binding protein required for splicing of both U2- and U12-type introns. Selectively interacts with t [...]
Dao protein networkhttps://string-db.org/network/10090.ENSMUSP00000107911D-amino-acid oxidase; Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent whi [...]
Ap1s2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107913AP-1 complex subunit sigma-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP co [...]
Gmppb protein networkhttps://string-db.org/network/10090.ENSMUSP00000107914Mannose-1-phosphate guanyltransferase beta; Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids.
Lrpprc protein networkhttps://string-db.org/network/10090.ENSMUSP00000107927Leucine-rich PPR motif-containing protein, mitochondrial; May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of [...]
Spc25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107939Kinetochore protein Spc25; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for ki [...]
Crybb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107955Beta-crystallin B2; Crystallins are the dominant structural components of the vertebrate eye lens.
B3galt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107965Beta-1,3-galactosyltransferase 1; Beta-1,3-galactosyltransferase that transfers galactose from UDP-alpha-D-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. [...]
Hps4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000107978Hermansky-Pudlak syndrome 4 protein homolog; Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, conv [...]
Scn1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000107985Sodium channel protein type 1 subunit alpha; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage diff [...]
Cryba4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108004Beta-crystallin A4; Crystallins are the dominant structural components of the vertebrate eye lens.
Pm20d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108012N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endoge [...]
Adgrg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108019Adhesion G-protein coupled receptor G2; Orphan receptor. Could be involved in a signal transduction pathway controlling epididymal function and male fertility. May regulate fluid exchange within [...]
Slc38a11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108039Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter.
Zfp384 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108046Zinc finger protein 384.
Cops7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000108058COP9 signalosome complex subunit 7a; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator [...]
Sh3kbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108075SH3 domain-containing kinase-binding protein 1; Adapter protein involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of [...]
Bclaf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108083BCLAF1 and THRAP3 family member 3; Belongs to the BCLAF1/THRAP3 family.
Map7d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108090MAP7 domain-containing protein 2.
Fcamr protein networkhttps://string-db.org/network/10090.ENSMUSP00000108096High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor; Functions as a receptor for the Fc fragment of IgA and IgM. Binds IgA and IgM with high affinity and mediates their endocytos [...]
Parp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108098Protein mono-ADP-ribosyltransferase PARP3; Mono-ADP-ribosyltransferase that mediates mono-ADP- ribosylation of target proteins and plays a key role in the response to DNA damage. Mediates mono-AD [...]
Slc4a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108099Sodium-driven chloride bicarbonate exchanger; Sodium/bicarbonate cotransporter which plays an important role in regulating intracellular pH. Has been shown to act as a sodium/bicarbonate cotransp [...]
Fez2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108106Fasciculation and elongation protein zeta-2; Involved in axonal outgrowth and fasciculation. Belongs to the zygin family.
Cd55b protein networkhttps://string-db.org/network/10090.ENSMUSP00000108107Complement decay-accelerating factor transmembrane isoform; This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are loc [...]
Crim1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108117Cysteine-rich motor neuron 1 protein; May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary f [...]
Pgam5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108124Serine/threonine-protein phosphatase PGAM5, mitochondrial; Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosph [...]
Fam98a protein networkhttps://string-db.org/network/10090.ENSMUSP00000108126Protein FAM98A; Positively stimulates PRMT1-induced protein arginine methylation (By similarity). Involved in skeletal homeostasis. Positively regulates lysosome peripheral distribution and ruffl [...]
Lipo3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108127Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
Chfr protein networkhttps://string-db.org/network/10090.ENSMUSP00000108138E3 ubiquitin-protein ligase CHFR; E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons. Acts in earl [...]
Pla2r1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108144Soluble secretory phospholipase A2 receptor; Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phospholipases sPLA2-IB/PLA2G1B, sPLA2-X/PLA2G10 and, with lower affinity, sPL [...]
Zfp605 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108147Zinc finger protein 605.
Sms protein networkhttps://string-db.org/network/10090.ENSMUSP00000108148Spermine synthase; Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM) (By similarity). Required for normal viability, growth and fertility; Belon [...]
Pex5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108151Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
Zranb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108157DNA annealing helicase and endonuclease ZRANB3; DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restar [...]
Zfp932 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108159Zinc finger protein 431; Sequence-specific DNA binding transcriptional repressor. Represses target gene transcription by recruiting HDAC1 and HDAC2 histone deacetylases. Acts as a specific transc [...]
Cd163 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108160Scavenger receptor cysteine-rich type 1 protein M130; Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin [...]
Gm15446 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108163Zinc finger protein.
4930522L14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000108166RIKEN cDNA 4930522L14 gene.
Baz2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000108169Bromodomain adjacent to zinc finger domain, 2B.
Magea6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108181Melanoma antigen, family A, 6.
Kctd12b protein networkhttps://string-db.org/network/10090.ENSMUSP00000108191Potassium channel tetramerisation domain-containing 12b.
Cypt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108192Cysteine-rich perinuclear theca 3.
Klf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108193Krueppel-like factor 8; Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) ph [...]
Nckap5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108202NCK-associated protein 5.
Apobec1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108205C->U-editing enzyme APOBEC-1; Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon [...]
Kdm5c protein networkhttps://string-db.org/network/10090.ENSMUSP00000108207Lysine-specific demethylase 5C; Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', [...]
Dpp10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108225Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipepti [...]
M6pr protein networkhttps://string-db.org/network/10090.ENSMUSP00000108229Cation-dependent mannose-6-phosphate receptor; Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl re [...]
Galnt5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108235Polypeptide N-acetylgalactosaminyltransferase 5; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threon [...]
Galnt13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108254Polypeptide N-acetylgalactosaminyltransferase 13; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threo [...]
Steap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108260Metalloreductase STEAP3; Endosomal ferrireductase required for efficient transferrin- dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe [...]
Evi5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108261Ecotropic viral integration site 5 protein; Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. May play a r [...]
3110009E18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000108263UPF0538 protein C2orf76 homolog.
Zbtb14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108296Zinc finger and BTB domain-containing protein 14; Transcriptional activator of the dopamine transporter (DAT), binding it's promoter at the consensus sequence 5'-CCTGCACAGTTCACGGA- 3'. Binds to 5 [...]
Slc25a18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108302Mitochondrial glutamate carrier 2; Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+) (By similarity); Belongs to the mitochondri [...]
Cecr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108306Cat eye syndrome critical region protein 2 homolog; Chromatin reader component of histone-modifying complexes, such as the CERF (CECR2-containing-remodeling factor) complex and ISWI- type complex [...]
Hfm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108310Probable ATP-dependent DNA helicase HFM1; Required for crossover formation and complete synapsis of homologous chromosomes during meiosis.
Gnl3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000108311Guanine nucleotide-binding protein-like 3-like protein; Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination an [...]
Rif1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108313Telomere-associated protein RIF1; Key regulator of TP53BP1 that plays a key role in the repair of double-strand DNA breaks (DSBs) in response to DNA damage: acts by promoting non-homologous end j [...]
Zfp644 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108318Zinc finger protein 644.
Cdh7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108321Cadherin-7; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the s [...]
Serpinb8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108326Serpin B8; Has an important role in epithelial desmosome-mediated cell- cell adhesion; Belongs to the serpin family. Ov-serpin subfamily.
Lrrc8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000108327Volume-regulated anion channel subunit LRRC8B; Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cel [...]
Tro protein networkhttps://string-db.org/network/10090.ENSMUSP00000108329Tro protein.
Ninj2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108331Ninjurin-2; Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues; Belongs to the ninjurin family [...]
Apex2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108340DNA-(apurinic or apyrimidinic site) lyase 2; Functions as a weak apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative [...]
Gm10413 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108348Predicted gene 10413.
Serpinb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108350Serpin B5; Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characte [...]
Gm15091 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108360Predicted gene 15091.
Bcl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108371Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial [...]
Gm8334 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108375Predicted gene 8334.
Dspp protein networkhttps://string-db.org/network/10090.ENSMUSP00000108391Dentin sialophosphoprotein; DSP may be an important factor in dentinogenesis. DPP may bind high amount of calcium and facilitate initial mineralization of dentin matrix collagen as well as regula [...]
Dcp1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000108397mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA m [...]
Gm15114 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108408Predicted gene 15114.
Cacna1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000108413Voltage-dependent L-type calcium channel subunit alpha-1C; Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calci [...]
Gm15107 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108416Predicted gene 15107.
Gm3012 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108421Predicted gene 3012.
Gm15080 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108423Predicted gene 15080.
Gtdc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108429Glycosyltransferase-like domain-containing protein 1.
Gm15128 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108433Predicted gene 15128.
Lrch2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108438Leucine-rich repeat and calponin homology domain-containing protein 2; May play a role in the organization of the cytoskeleton.
Ankrd26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108449Ankyrin repeat domain-containing protein 26; Acts as a regulator of adipogenesis. Involved in the regulation of the feeding behavior.
Amot protein networkhttps://string-db.org/network/10090.ENSMUSP00000108455Angiomotin; Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regula [...]
Rtl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108462Retrotransposon Gag-like protein 4; Involved in cognitive function in the brain, possibly via the noradrenergic system.
Gin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108464Gypsy retrotransposon integrase-like protein 1.
Zfp637 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108481Zinc finger protein 32; May be involved in transcriptional regulation.
Arpc5l protein networkhttps://string-db.org/network/10090.ENSMUSP00000108483Actin-related protein 2/3 complex subunit 5-like protein; May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating n [...]
Pak3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108484Serine/threonine-protein kinase PAK 3; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cy [...]
Wdr38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108493WD repeat-containing protein 38.
Nr6a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108498Nuclear receptor subfamily 6 group A member 1; Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression i [...]
Chrdl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108499Chordin-like protein 1; Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis t [...]
D2hgdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000108502D-2-hydroxyglutarate dehydrogenase, mitochondrial; Catalyzes the oxidation of D-2-hydroxyglutarate to alpha- ketoglutarate.
Nr5a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108504Steroidogenic factor 1; Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter [...]
Dzip1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000108506Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane (By similar [...]
Gpat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108508Glycerol-3-phosphate acyltransferase 3; Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3- phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the [...]
Tmem164 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108517Transmembrane protein 164.
Zfand4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108521AN1-type zinc finger protein 4.
Plac8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108531Placenta-specific gene 8 protein; Belongs to the cornifelin family.
Faim protein networkhttps://string-db.org/network/10090.ENSMUSP00000108532Fas apoptotic inhibitory molecule 1; Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells.
Nxt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108538NTF2-related export protein 2; Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export (By similarity).
Col4a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108553Collagen, type IV, alpha 5.
Zbtb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108554Zinc finger and BTB domain-containing protein 6; May be involved in transcriptional regulation.
Cntf protein networkhttps://string-db.org/network/10090.ENSMUSP00000108555Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
Nmnat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108557Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic aci [...]
Pdcl protein networkhttps://string-db.org/network/10090.ENSMUSP00000108562Phosducin-like protein; Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers. Acts [...]
Mpeg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108573Macrophage-expressed gene 1 protein; Plays a key role in the innate immune response following bacterial infection by polymerizing and inserting into the bacterial surface to form pores. By breach [...]
Gm11111 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108579Predicted gene 11111.
Kif1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000108582Kinesin-like protein KIF1A; Motor for anterograde axonal transport of synaptic vesicle precursors (Probable). Also required for neuronal dense core vesicles (DCVs) transport to the dendritic spin [...]
Prdm8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108583PR domain zinc finger protein 8; Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3. Histone methyltransferase activity has not been confirmed in other species. In [...]
Lhx6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108584LIM/homeobox protein Lhx6; Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cor [...]
Paqr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108593Progestin and adipoQ receptor family member 3; Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi; Belongs to the ADIPOR family.
Atg4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000108595Cysteine protease ATG4A; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal gl [...]
Catsperd protein networkhttps://string-db.org/network/10090.ENSMUSP00000108603Cation channel sperm-associated protein subunit delta; Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm [...]
Ms4a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108608Membrane-spanning 4-domains subfamily A member 3; Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2) through it [...]
Mid2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108617Probable E3 ubiquitin-protein ligase MID2; May play a role in microtubule stabilization. Belongs to the TRIM/RBCC family.
Tsc22d3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108620TSC22 domain family protein 3; Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apopt [...]
Cnot6l protein networkhttps://string-db.org/network/10090.ENSMUSP00000108629CCR4-NOT transcription complex subunit 6-like; Poly(A) nuclease with 3'-5' RNase activity. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is [...]
4930402F06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000108633RIKEN cDNA 4930402F06 gene.
Rbm41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108634RNA-binding protein 41; May bind RNA.
Rnf128 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108649E3 ubiquitin-protein ligase RNF128; E3 ubiquitin-protein ligase that catalyzes 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains formation. Functions as an inhibitor of cytokine gene transcripti [...]
Dipk2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000108651Divergent protein kinase domain 2A; May play a role in cardiomyocyte proliferation through paracrine signaling and activation of the PI3-kinase signaling cascade. Belongs to the DIPK family.
Radx protein networkhttps://string-db.org/network/10090.ENSMUSP00000108653RPA-related protein RADX; Single-stranded DNA-binding protein recruited to replication forks to maintain genome stability. Prevents fork collapse by antagonizing the accumulation of RAD51 at fork [...]
Cntrl protein networkhttps://string-db.org/network/10090.ENSMUSP00000108655Centriolin; Involved in cell cycle progression and cytokinesis. During the late steps of cytokinesis, anchors exocyst and SNARE complexes at the midbody, thereby allowing secretory vesicle-mediat [...]
Pwwp3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000108666PWWP domain-containing DNA repair factor 3B; Belongs to the PWWP3A family.
Shroom3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108678Protein Shroom3; Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and [...]
Adamts7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108682A disintegrin and metalloproteinase with thrombospondin motifs 7; Metalloprotease that may play a role in the degradation of COMP.
Il1rapl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108686X-linked interleukin-1 receptor accessory protein-like 2; Belongs to the interleukin-1 receptor family.
Cutal protein networkhttps://string-db.org/network/10090.ENSMUSP00000108691CutA divalent cation tolerance homolog-like.
Slc25a53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108692Solute carrier family 25, member 53; Belongs to the mitochondrial carrier (TC 2.A.29) family.
Tmsb15b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108694Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymos [...]
Cidec protein networkhttps://string-db.org/network/10090.ENSMUSP00000108712Cell death activator CIDE-3; Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes d [...]
Rpusd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108715Mitochondrial mRNA pseudouridine synthase Rpusd3; Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs), a post- transcriptional modifica [...]
Cxcl9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108716C-X-C motif chemokine 9; May be a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response.
Iqca protein networkhttps://string-db.org/network/10090.ENSMUSP00000108717Dynein regulatory complex protein 11; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the di [...]
Tceal3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108724Transcription elongation factor A protein-like 3; May be involved in transcriptional regulation; Belongs to the TFS-II family. TFA subfamily.
Naaa protein networkhttps://string-db.org/network/10090.ENSMUSP00000108726N-acylethanolamine-hydrolyzing acid amidase subunit alpha; Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N-palmitoylethanolamine > N- myristoyl [...]
Kir3dl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108729Killer cell immunoglobulin-like receptor 3DL1; Receptor on natural killer (NK) cells. Inhibits the activity of NK cells thus preventing cell lysis; Belongs to the immunoglobulin superfamily.
Kir3dl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108732Killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2.
Mthfsl protein networkhttps://string-db.org/network/10090.ENSMUSP000001087345-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
Tceal7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108741Transcription elongation factor A protein-like 7; Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its ta [...]
Brpf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108744Peregrin; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Preferentially mediates histone H3-K23 acetylation. Positively regulates the transcription of RUNX1 [...]
Mroh2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000108755Maestro heat-like repeat-containing protein family member 2A.
Ugt1a6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000108759UDP-glucuronosyltransferase 1-6; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Conjugates small planar phen [...]
Ugt1a7c protein networkhttps://string-db.org/network/10090.ENSMUSP00000108760UDP glucuronosyltransferase 1 family, polypeptide A7C.
Ugt1a6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000108763UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
Ugt1a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108764UDP-glucuronosyltransferase 1-7C; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificit [...]
Ugt1a10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108767UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
Gprasp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108769G-protein coupled receptor-associated sorting protein 1; Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation [...]
Mtmr14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108771Myotubularin-related protein 14; Lipid phosphatase which efficiently dephosphorylates phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2; inactive toward PtdIns4P, PtdIns(3,4)P2, PtdIn [...]
Mrap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108774Melanocortin-2 receptor accessory protein 2; Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and [...]
Zbtb34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108783Zinc finger and BTB domain-containing 34.
Prame protein networkhttps://string-db.org/network/10090.ENSMUSP00000108784Preferentially-expressed antigen in melanoma.
Rab3il1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108786Guanine nucleotide exchange factor for Rab-3A; Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP [...]
Nxf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108788Nuclear mRNA export factor 7.
Gm7903 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108797Predicted gene 5128.
Pramel3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108801Preferentially-expressed antigen in melanoma-like 3.
Afm protein networkhttps://string-db.org/network/10090.ENSMUSP00000108804Afamin; Functions as carrier for hydrophobic molecules in body fluids. Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, [...]
Gm15023 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108808Predicted gene 15023.
Atg16l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108815Autophagy-related protein 16-1; Plays an essential role in autophagy: interacts with ATG12- ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C [...]
Armcx6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108819Protein ARMCX6; May regulate the dynamics and distribution of mitochondria in neural cells.
Armcx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108824Armadillo repeat-containing X-linked protein 1; Regulates mitochondrial transport during axon regeneration. Increases the proportion of motile mitochondria by recruiting stationary mitochondria i [...]
Lrsam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108825E3 ubiquitin-protein ligase LRSAM1; E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF re [...]
Hnrnph2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108828Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for th [...]
Rpl36a protein networkhttps://string-db.org/network/10090.ENSMUSP00000108837Ribosomal protein L36A.
Kcnj13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108838Inward rectifier potassium channel 13; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage de [...]
Sh3bgrl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108841SH3 domain-binding glutamic acid-rich-like protein 2.
Eif4e2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108859Eukaryotic translation initiation factor 4E type 2; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation. Acts as a repressor of translation initi [...]
Trem2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108863Triggering receptor expressed on myeloid cells 2; Forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding. Acts as a receptor for amyl [...]
Crbn protein networkhttps://string-db.org/network/10090.ENSMUSP00000108865Protein cereblon; Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, [...]
Irak1bp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108871Interleukin-1 receptor-associated kinase 1-binding protein 1; Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Ac [...]
Impg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108876Interphotoreceptor matrix proteoglycan 1; May interact with hyaluronan which may serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix.
Trmt2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000108878tRNA (uracil(54)-C(5))-methyltransferase homolog; Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNA. [...]
Cntn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108889Contactin-4; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis; Belongs to the immun [...]
Alpi protein networkhttps://string-db.org/network/10090.ENSMUSP00000108895Alkaline phosphatase.
Csn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108896Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
Frs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108921Fibroblast growth factor receptor substrate 3; Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 si [...]
Slc22a29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108923Solute carrier family 22. member 29.
Prickle4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108925Prickle planar cell polarity protein 4.
Tomm6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108927Mitochondrial import receptor subunit TOM6 homolog; Belongs to the Tom6 family.
Srpx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108929Sushi repeat-containing protein SRPX2; Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the forma [...]
B3gnt7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108931UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7; May be involved in keratane sulfate biosynthesis. Transfers N-acetylgalactosamine on to keratan sulfate-related glycans. May play a [...]
Armc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108934LisH domain-containing protein ARMC9; Acts as a positive regulator of hedgehog (Hh) signaling. Involved in ciliogenesis (By similarity). May participate in the trafficking and/or retention of GLI [...]
Sult1d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108940Sulfotransferase 1 family member D1; Sulfotransferase with broad substrate specificity that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation o [...]
Foxp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108948Forkhead box protein P1; Transcriptional repressor. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays an important role in the specification and diffe [...]
Ciz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108960CDKN1A-interacting zinc finger protein 1.
Ubr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108963E3 ubiquitin-protein ligase UBR2; E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are desta [...]
Cldn34c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108975Claudin 34C1.
Pcdh11x protein networkhttps://string-db.org/network/10090.ENSMUSP00000108985Protocadherin 11 X-linked.
Cab39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108987Calcium-binding protein 39; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25bet [...]
Ddx43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000108994DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family.
Flrt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109010Leucine-rich repeat transmembrane protein FLRT1; Plays a role in fibroblast growth factor-mediated signaling cascades that lead to the activation of MAP kinases. Promotes neurite outgrowth via FG [...]
Swi5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109027DNA repair protein SWI5 homolog; Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. Belongs to the SWI5/SAE3 family.
Zfp711 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109036Zinc finger protein 711; Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demet [...]
2010106E10Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000109039RIKEN cDNA 2010106E10 gene.
Hdx protein networkhttps://string-db.org/network/10090.ENSMUSP00000109049Highly divergent homeobox.
Ccl20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109064C-C motif chemokine 20; Acts as a ligand for C-C chemokine receptor CCR6. Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellula [...]
Ccdc88b protein networkhttps://string-db.org/network/10090.ENSMUSP00000109067Coiled-coil domain-containing protein 88B; Acts as a positive regulator of T-cell maturation and inflammatory function. Required for several functions of T-cells in both the CD4(+) and the CD8(+) [...]
Slc22a12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109078Solute carrier family 22 member 12; Required for efficient urate re-absorption in the kidney. Regulates blood urate levels. Mediates saturable urate uptake by facilitating the exchange of urate a [...]
Col4a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109084Collagen alpha-3(IV) chain; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and [...]
Nrxn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109089Neurexin-2; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.
Nr2c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109090Nuclear receptor subfamily 2 group C member 2; Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways suc [...]
Crip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109092Cysteine-rich protein 3.
Prdm12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109098PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation.
Rasgrp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109104RAS guanyl-releasing protein 2; Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates othe [...]
Cysltr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109108Cysteinyl leukotriene receptor 1; Receptor for cysteinyl leukotrienes mediating constriction of the microvascular smooth muscle during an inflammatory response. This response is mediated via a G- [...]
Zfp318 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109109Zinc finger protein 318; [Isoform 2]: Acts as a transcriptional corepressor for AR- mediated transactivation function. May act as a transcriptional regulator during spermatogenesis and in particu [...]
Exoc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109121Exocyst complex component 1; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Taf9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000109123Transcription initiation factor TFIID subunit 9B; Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of [...]
Men1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109130Menin; Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Bi [...]
Wdfy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109140WD repeat and FYVE domain-containing protein 1; Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand [...]
Kdr protein networkhttps://string-db.org/network/10090.ENSMUSP00000109144Vascular endothelial growth factor receptor 2; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, [...]
Tmem63b protein networkhttps://string-db.org/network/10090.ENSMUSP00000109151CSC1-like protein 2; Acts as an osmosensitive calcium-permeable cation channel. Mechanosensitive ion channel that converts mechanical stimuli into a flow of ion. Belongs to the CSC1 (TC 1.A.17) f [...]
Mogat1 protein networkhttps://string-db.org/network/10090.ENSMUSP000001091522-acylglycerol O-acyltransferase 1; Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Probably not involved in absorption of dietary fat in the small intestin [...]
Gpha2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109154Glycoprotein hormone alpha-2; Functions as a heterodimeric glycoprotein hormone with GPHB5 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP pro [...]
Majin protein networkhttps://string-db.org/network/10090.ENSMUSP00000109156Membrane-anchored junction protein; Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and s [...]
Hmcn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109160Hemicentin-2.
Sac3d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109161SAC3 domain-containing protein 1; Involved in centrosome duplication and mitotic progression. Belongs to the SAC3 family.
Fip1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109164Pre-mRNA 3'-end-processing factor FIP1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA [...]
Tcte1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109175Dynein regulatory complex subunit 5; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the dist [...]
Fnbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109190Formin-binding protein 1; Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage of clathrin-mediated endocytosis. Binds to lipids such as [...]
Obsl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109197Obscurin-like protein 1; Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it co [...]
Runx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109201Runt-related transcription factor 2; Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous [...]
Atrx protein networkhttps://string-db.org/network/10090.ENSMUSP00000109203Transcriptional regulator ATRX; Involved in transcriptional regulation and chromatin remodeling. Facilitates DNA replication in multiple cellular environments and is required for efficient replic [...]
Gmppa protein networkhttps://string-db.org/network/10090.ENSMUSP00000109214Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose; Belongs to the transferase hexapeptide repeat fami [...]
Adgrf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109229Adhesion G protein-coupled receptor F5; Receptor that plays a critical role in lung surfactant homeostasis. May play a role in controlling adipocyte function.
Rab7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109230Ras-related protein Rab-7a; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and po [...]
1700011M02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000109232RIKEN cDNA 1700011M02 gene.
Hmces protein networkhttps://string-db.org/network/10090.ENSMUSP00000109236Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites (By similarity). A [...]
Copg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109237Coatomer subunit gamma-1; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosy [...]
Dmrtc1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000109239Doublesex and mab-3 related transcription factor 8.2 isoform c.
Gm9112 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109240Predicted gene 9112.
Adgrf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109244Adhesion G-protein coupled receptor F2; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Pcnx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109245Pecanex-like protein 3; Belongs to the pecanex family.
Sh3glb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109251Endophilin-B2.
Glb1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000109253Beta-galactosidase-1-like protein; Probable glycosyl hydrolase.
Pin4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109257Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4; Involved as a ribosomal RNA processing factor in ribosome biogenesis. Binds to tightly bent AT-rich stretches of double-stranded DNA (By si [...]
Rtl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109261Retrotransposon Gag-like protein 5.
Arhgap25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109267Rho GTPase-activating protein 25; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Kat5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109271Histone acetyltransferase KAT5; Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucle [...]
Gfpt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109288Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N [...]
Kyat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109291Kynurenine--oxoglutarate transaminase 1; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of [...]
Znrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109299DNA-directed RNA polymerase I subunit RPA12; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA p [...]
Drap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109304Dr1-associated corepressor; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction [...]
Anxa4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109305Annexin A4; Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.
Myg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109312UPF0160 protein MYG1, mitochondrial.
Trim39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109336E3 ubiquitin-protein ligase TRIM39; E3 ubiquitin-protein ligase (By similarity). May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated [...]
Tpm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109337Tropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebra [...]
Slc7a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109339Cationic amino acid transporter 3; Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner.
Wdr34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109340WD repeat-containing protein 34; Critical for ciliary functions, essential to normal development and survival, most probably as a previously unrecognized component of the mammalian dynein-motor-b [...]
Zbtb21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109363Zinc finger and BTB domain-containing 21.
Gm11127 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109371Predicted gene 11127; Belongs to the MHC class I family.
Tprkb protein networkhttps://string-db.org/network/10090.ENSMUSP00000109382EKC/KEOPS complex subunit Tprkb; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons [...]
Odf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109388Outer dense fiber protein 2; Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and princi [...]
H2-T24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109389Histocompatibility 2, T region locus 24; Belongs to the MHC class I family.
Arr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109398Arrestin-C; May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins.
Rpl9 protein networkhttps://string-db.org/network/10090.ENSMUSP0000010939960S ribosomal protein L9; Belongs to the universal ribosomal protein uL6 family.
Eda protein networkhttps://string-db.org/network/10090.ENSMUSP00000109409Ectodysplasin-A, membrane form; Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain contain [...]
Pja1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109423E3 ubiquitin-protein ligase Praja-1; Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome. May be involved in pr [...]
Igsf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109425Immunoglobulin superfamily member 5; Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithel [...]
Gm49948 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109426Predicted gene, 49948.
Tmbim1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109427Protein lifeguard 3; Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling. Belongs to the BI1 family. LFG subfamily.
B3galt5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109431Beta-1,3-galactosyltransferase 5; Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Ce [...]
Gm13547 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109441Predicted gene 13547.
Arpc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109451Actin-related protein 2/3 complex subunit 2; Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting fact [...]
Nagk protein networkhttps://string-db.org/network/10090.ENSMUSP00000109482N-acetyl-D-glucosamine kinase; Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosph [...]
Ddx31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109484Probable ATP-dependent RNA helicase DDX31; Probable ATP-dependent RNA helicase (By similarity). Plays a role in ribosome biogenesis and TP53/p53 regulation through its interaction with NPM1 (By s [...]
Kcnj15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109493ATP-sensitive inward rectifier potassium channel 15; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Th [...]
Tsc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109500Hamartin; In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicat [...]
Amer1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109502APC membrane recruitment protein 1; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell [...]
Arhgef9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109510Rho guanine nucleotide exchange factor 9; Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters (By similarity).
Gtf3c5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109521General transcription factor 3C polypeptide 5; Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly bi [...]
Gspt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109523Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulat [...]
Apoo protein networkhttps://string-db.org/network/10090.ENSMUSP00000109530MICOS complex subunit Mic26; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner mem [...]
Pigp protein networkhttps://string-db.org/network/10090.ENSMUSP00000109547Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first [...]
Klhl15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109548Kelch-like protein 15; Substrate-specific adapter for CUL3 E3 ubiquitin-protein ligase complex. Acts as an adapter for CUL3 to target the serine/threonine-protein phosphatase 2A (PP2A) subunit PP [...]
Dctn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109552Dynactin subunit 1; Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds to both dynein [...]
Mrpl53 protein networkhttps://string-db.org/network/10090.ENSMUSP0000010957139S ribosomal protein L53, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL53 family.
Brd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109574Bromodomain-containing protein 3; Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and in [...]
Wdr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109585WD repeat-containing protein 5; Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is invo [...]
Mageb18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109588Melanoma-associated antigen B18; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization o [...]
4932429P05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000109591RIKEN cDNA 4932429P05 gene.
Dcaf8l protein networkhttps://string-db.org/network/10090.ENSMUSP00000109592DDB1 and CUL4-associated factor 8-like.
Il1rapl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109599Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate th [...]
Mageb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109602Melanoma-associated antigen B4.
Kmt5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000109606Histone-lysine N-methyltransferase KMT5B; Histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20' (H4K20me2) of histone H4 to produce r [...]
Slc5a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109608Sodium/myo-inositol cotransporter; Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function.
5430427O19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000109609Protein CXorf21 homolog; Plays a role in the regulation of endolysosomal pH in immune cells such as B-cells, dendritic cells and monocytes. May be involved in endolysosomal-dependent immune respo [...]
Gk protein networkhttps://string-db.org/network/10090.ENSMUSP00000109611Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism.
Lancl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109612Glutathione S-transferase LANCL1; Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitropheny [...]
M1ap protein networkhttps://string-db.org/network/10090.ENSMUSP00000109613Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis.
Rpe protein networkhttps://string-db.org/network/10090.ENSMUSP00000109628Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate.
Ppp6r3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109630Serine/threonine-protein phosphatase 6 regulatory subunit 3; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. May have an important role in maintainin [...]
Dmd protein networkhttps://string-db.org/network/10090.ENSMUSP00000109633Dystrophin; Anchors the extracellular matrix to the cytoskeleton via F- actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neurom [...]
Itsn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109635Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereb [...]
Cacfd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109640Calcium channel flower homolog; Belongs to the calcium channel flower family.
Map2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109646Microtubule-associated protein 2; The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubule [...]
Rexo4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109653RNA exonuclease 4; May function as an exonuclease.
Prrg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109659Proline-rich Gla (G-carboxyglutamic acid) 1.
Gm14743 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109660Predicted gene 14743; Belongs to the calycin superfamily. Lipocalin family.
Gm5938 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109664Predicted gene 5938; Belongs to the calycin superfamily. Lipocalin family.
Son protein networkhttps://string-db.org/network/10090.ENSMUSP00000109671Protein SON; RNA-binding protein that acts as a mRNA splicing cofactor by promoting efficient splicing of transcripts that possess weak splice sites. Specifically promotes splicing of many cell-c [...]
Gm14744 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109673Predicted gene 14744; Belongs to the calycin superfamily. Lipocalin family.
Tmsb10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109683Thymosin beta-10; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity); Be [...]
Tcf7l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109687Transcription factor 7-like 1; Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the ter [...]
Cldn34d protein networkhttps://string-db.org/network/10090.ENSMUSP00000109688Claudin 34D.
Pls3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109692Plastin-3; Actin-bundling protein.
Crygc protein networkhttps://string-db.org/network/10090.ENSMUSP00000109698Gamma-crystallin C; Crystallins are the dominant structural components of the vertebrate eye lens.
Elmod3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109703ELMO domain-containing protein 3; Acts as a GTPase-activating protein (GAP) for ARL2 with low specific activity.
Capg protein networkhttps://string-db.org/network/10090.ENSMUSP00000109705Macrophage-capping protein; Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrop [...]
Klf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109720Krueppel-like factor 7; Transcriptional factor. Plays a critical role in neuronal morphogenesis. Represses the corneal epithelium differentiation (By similarity). Acts also as a metabolic regulat [...]
Mdh1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000109728Putative malate dehydrogenase 1B; Belongs to the LDH/MDH superfamily. MDH type 2 family.
Otop1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109734Proton channel OTOP1; Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly- sensitive to voltage. Proton-selective channel activity is [...]
Entr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109737Endosome-associated-trafficking regulator 1; May be involved in modulation of TNF response. May be involved in presentation of TNFRSF1A on the cell surface. Involved in the endosome-to-plasma mem [...]
Gm5936 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109751Predicted gene 5936.
Ctag2l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109752CTAG2-like 2.
Gm5640 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109754Predicted gene 5640.
Ctag2l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109760CTAG2-like 1.
Stx18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109761Syntaxin-18; Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER; Belongs to the syntaxin family.
Zdbf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109767DBF4-type zinc finger-containing protein 2 homolog.
Fam3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000109779Protein FAM3A.
Nrp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109794Neuropilin-2; High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.
Crmp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109795Dihydropyrimidinase-related protein 1; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance proces [...]
Nacc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109796Nucleus accumbens-associated protein 2; Functions as a transcriptional repressor through its association with the NuRD complex. Recruits the NuRD complex to the promoter of MDM2, leading to the r [...]
Fam50a protein networkhttps://string-db.org/network/10090.ENSMUSP00000109797Protein FAM50A; May be a DNA-binding protein or transcriptional factor.
Camsap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109804Calmodulin-regulated spectrin-associated protein 1; Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organ [...]
Cyyr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109811Cysteine and tyrosine-rich protein 1.
Chmp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109815Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation [...]
Taz protein networkhttps://string-db.org/network/10090.ENSMUSP00000109818Tafazzin family protein; Some isoforms may be involved in cardiolipin metabolism.
Obp2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000109830Odorant-binding protein 2B; Belongs to the calycin superfamily. Lipocalin family.
Jam2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109833Junctional adhesion molecule B; Junctional adhesion protein that mediates heterotypic cell- cell interactions with its cognate receptor JAM3 to regulate different cellular processes. Plays a role [...]
Lcn6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109837LCN6 isoform alpha; Belongs to the calycin superfamily. Lipocalin family.
Fam219b protein networkhttps://string-db.org/network/10090.ENSMUSP00000109838Protein FAM219B.
Ajm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109855Apical junction component 1 homolog; May be involved in the control of adherens junction integrity.
H2-DMb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109870Class II histocompatibility antigen, M beta 1 chain; Plays a critical role in catalyzing the release of class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized clas [...]
Traf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109872TNF receptor-associated factor 2; Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switch [...]
Tnip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109874TNFAIP3-interacting protein 3.
Samsn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109877SAM domain-containing protein SAMSN-1; Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization [...]
Gm973 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109881Predicted gene 973.
Fzd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109884Frizzled-7; Receptor for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK [...]
Cdk15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109886Cyclin-dependent kinase 15; Serine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'.
Rbm11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109891Splicing regulator RBM11; Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-media [...]
Lingo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109894Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation resp [...]
Paxx protein networkhttps://string-db.org/network/10090.ENSMUSP00000109899Protein PAXX; Involved in non-homologous end joining (NHEJ), a major pathway to repair double-strand breaks in DNA. May act as a scaffold required to stabilize the Ku heterodimer, composed of XRC [...]
Peak1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109901Inactive tyrosine-protein kinase PEAK1; Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adh [...]
Clic3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109904Chloride intracellular channel protein 3; Can insert into membranes and form chloride ion channels. May participate in cellular growth control (By similarity); Belongs to the chloride channel CLI [...]
Snca protein networkhttps://string-db.org/network/10090.ENSMUSP00000109907Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monom [...]
Mpp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109914MAGUK p55 subfamily member 4; May play a role in retinal photoreceptors development. Belongs to the MAGUK family.
Rcn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109915Reticulocalbin-2; Not known. Binds calcium (By similarity).
Vopp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109936Vesicular, overexpressed in cancer, prosurvival protein 1; Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response [...]
Flna protein networkhttps://string-db.org/network/10090.ENSMUSP00000109938Filamin-A; Actin binding protein that promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cyt [...]
Cflar protein networkhttps://string-db.org/network/10090.ENSMUSP00000109952CASP8 and FADD-like apoptosis regulator subunit p12; Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an [...]
Kbtbd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109960Kelch repeat and BTB (POZ) domain-containing 2.
Tex28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109967Testis-expressed 28.
Tprn protein networkhttps://string-db.org/network/10090.ENSMUSP00000109975Taperin; Belongs to the taperin family.
Add1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109979Alpha-adducin; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
Gabrr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109980Gamma-aminobutyric acid (GABA) receptor, rho 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
Ndor1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109989NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of [...]
Rnf208 protein networkhttps://string-db.org/network/10090.ENSMUSP00000109995RING finger protein 208.
Aox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110006Aldehyde oxidase 2; Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as phthalazine, as well as aldehydes, such as benzaldehyde and retinal. Cannot use hypoxanth [...]
Cmss1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110011Protein CMSS1; Belongs to the CMS1 family.
Rab11b protein networkhttps://string-db.org/network/10090.ENSMUSP00000110021Ras-related protein Rab-11B; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle be [...]
Entpd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110022Ectonucleoside triphosphate diphosphohydrolase 8; Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- a [...]
Kctd18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110052Potassium channel tetramerisation domain-containing 18.
Satb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110057DNA-binding protein SATB2; Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double- stranded DNA. Transcription factor contro [...]
Btg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110074Protein BTG4; Shows marked antiproliferative activity, being able to induce G(1) arrest.
Hoxa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110077Homeobox protein Hox-A3; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Pcnp protein networkhttps://string-db.org/network/10090.ENSMUSP00000110087PEST proteolytic signal-containing nuclear protein; May be involved in cell cycle regulation.
Maea protein networkhttps://string-db.org/network/10090.ENSMUSP00000110093E3 ubiquitin-protein transferase MAEA; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent prot [...]
Cblb protein networkhttps://string-db.org/network/10090.ENSMUSP00000110115E3 ubiquitin-protein ligase CBL-B; E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their de [...]
Plet1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110118Placenta-expressed transcript 1 protein; Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a ro [...]
Il1rn protein networkhttps://string-db.org/network/10090.ENSMUSP00000110126Interleukin-1 receptor antagonist protein; Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no inte [...]
Osgepl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110128Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that r [...]
Gls protein networkhttps://string-db.org/network/10090.ENSMUSP00000110158Glutaminase kidney isoform, mitochondrial 65 kDa chain; Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasi [...]
Spin2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000110162Spindlin family, member 2D.
Xlr5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000110164X-linked lymphocyte-regulated 5B.
Acbd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110175Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medi [...]
Lrrc61 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110192Leucine-rich repeat-containing protein 61.
Tmprss3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110196Transmembrane protease serine 3; Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is r [...]
Cetn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110198Centrin-2; Plays a fundamental role in microtubule organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis [...]
Umodl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110202Uromodulin-like 1.
Zfp467 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110208Zinc finger protein 467; Transcription factor that promotes adipocyte differentiation and suppresses osteoblast differentiation in the bone marrow. Enhances the osteoclast-supporting ability of s [...]
Tmprss7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110209Transmembrane protease serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position; Belongs to the peptidase S1 family.
Krba1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110219Protein KRBA1.
Sidt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110220SID1 transmembrane family member 2; Mediates the translocation of RNA and DNA across the lysosomal membrane during RNA and DNA autophagy (RDA), a process in which RNA and DNA is directly imported [...]
Glp1r protein networkhttps://string-db.org/network/10090.ENSMUSP00000110221Glucagon-like peptide 1 receptor; G-protein coupled receptor for glucagon-like peptide 1 (GLP- 1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenyl [...]
Vma21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110222Vacuolar ATPase assembly integral membrane protein Vma21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family.
Hmgb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110229High mobility group protein B3; Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a [...]
Zfp777 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110230Zinc finger protein 777.
Gm609 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110233Predicted gene 609.
Zfp513 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110238Zinc finger protein 513; Transcriptional regulator that plays a role in retinal development and maintenance.
Eif2b4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110250Translation initiation factor eIF-2B subunit delta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP.
Cd200r3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110258Cell surface glycoprotein CD200 receptor 3; According to isoform 4 is a receptor for the CD200 cell surface glycoprotein. According to isoform 4 is not a receptor for the CD200/OX2 cell surface g [...]
Etl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110274Sickle tail protein; Required for normal development of intervertebral disks.
Boc protein networkhttps://string-db.org/network/10090.ENSMUSP00000110281Brother of CDO; Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells.
Armc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110287Armadillo repeat-containing protein 3.
Cntnap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110288Contactin-associated protein-like 2; Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical fo [...]
Mpzl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110312Myelin protein zero-like protein 3; Mediates homophilic cell-cell adhesion.
Atp6v1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000110314V-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular comp [...]
Slc5a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110316Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Gm14692 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110320Predicted gene 14692.
Gm1140 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110323Predicted gene 1140.
Gm6760 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110330Predicted gene 6760.
Zbtb20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110342Zinc finger and BTB domain-containing protein 20; May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses (By similarity). Plays a role in postnatal [...]
Agbl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110348Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates protein deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains g [...]
Pi16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110349Peptidase inhibitor 16; May inhibit cardiomyocyte growth.
Bivm protein networkhttps://string-db.org/network/10090.ENSMUSP00000110357Basic immunoglobulin-like variable motif-containing protein.
Cacnb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110371Voltage-dependent L-type calcium channel subunit beta-2; The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium curre [...]
Gm364 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110373Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
Rbmx protein networkhttps://string-db.org/network/10090.ENSMUSP00000110374RNA-binding motif protein, X chromosome, N-terminally processed; RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes. Implicated in tissue- sp [...]
Dpysl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110377Dihydropyrimidinase-related protein 5; May have a function in neuronal differentiation and/or axon growth.
Ephb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110380Ephrin type-B receptor 6; Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negat [...]
Pstpip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110389Proline-serine-threonine phosphatase-interacting protein 2; Binds to F-actin. May be involved in regulation of the actin cytoskeleton.
Gsk3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000110398Glycogen synthase kinase-3 beta; Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcripti [...]
Hacd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110401Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, [...]
Fstl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110411Follistatin-related protein 1; May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin (By similarity).
Slc26a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110412Testis anion transporter 1; Acts as a DIDS-sensitive anion exchanger mediating chloride, sulfate and oxalate transport. May fulfill critical anion exchange functions in male germ line during meio [...]
Tmem182 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110413Transmembrane protein 182.
Map7d3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110414MAP7 domain-containing protein 3; Promotes the assembly and stability of microtubules. Belongs to the MAP7 family.
Fhl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110417Four and a half LIM domains protein 1; May have an involvement in muscle development or hypertrophy. Isoform 2 binds to RBP-J and plays a negative regulatory role in the RBP-J-mediated transcript [...]
Pias2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110425E3 SUMO-protein ligase PIAS2; Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Pla [...]
Hadhb protein networkhttps://string-db.org/network/10090.ENSMUSP00000110434Trifunctional enzyme subunit beta, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial [...]
Stxbp5l protein networkhttps://string-db.org/network/10090.ENSMUSP00000110435Syntaxin-binding protein 5-like; Plays a role in vesicle trafficking and exocytosis inhibition. In pancreatic beta-cells, inhibits insulin secretion probably by interacting with and regulating ST [...]
Fkbp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110440Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-sho [...]
Tead3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110447Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting pr [...]
Fance protein networkhttps://string-db.org/network/10090.ENSMUSP00000110451Fanconi anemia, complementation group E.
C1qtnf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110469Complement C1q tumor necrosis factor-related protein 5.
Eaf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110477ELL-associated factor 2; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities (By similarity). Acts as a transcriptional transactivator of TCEA1 elongation activity; Bel [...]
Rnf26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110478E3 ubiquitin-protein ligase RNF26; E3 ubiquitin-protein ligase that plays a key role in endosome organization by retaining vesicles in the perinuclear cloud. Acts as a platform for perinuclear po [...]
Thy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110489Thy-1 membrane glycoprotein; May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Plac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110492Placenta-specific protein 1; May play a role in placental development. Belongs to the PLAC1 family.
Taf11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110498Transcription initiation factor TFIID subunit 11; Core TAFII present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectivel [...]
Uhrf1bp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110499UHRF1 (ICBP90)-binding protein 1.
Cstdc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110500Cystatin domain-containing 6.
Cstdc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110508Cystatin domain-containing 4; Belongs to the cystatin family.
Ilrun protein networkhttps://string-db.org/network/10090.ENSMUSP00000110513Protein ILRUN; Negative regulator of innate antiviral response. Blocks IRF3- dependent cytokine production such as IFNA, IFNB and TNF. Interacts with IRF3 and inhibits IRF3 recruitment to type I [...]
Grik4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110515Glutamate receptor ionotropic, kainate 4; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Gl [...]
Usp26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110519Ubiquitin carboxyl-terminal hydrolase 26; Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome. Deubiquitinates the androgen receptor and regulates the a [...]
Clec2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000110524C-type lectin domain family 2 member L.
Mbnl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110526Muscleblind-like protein 3; Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) [...]
Parp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110528Protein mono-ADP-ribosyltransferase PARP9; ADP-ribosyltransferase which, in association with E3 ligase DTX3L, plays a role in DNA damage repair and in immune responses including interferon-mediat [...]
Rps10 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011053240S ribosomal protein S10; Component of the 40S ribosomal subunit.
Lyg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110544Lysozyme g-like protein 1.
Cfap53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110545Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis.
Atp5c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110547ATP synthase subunit gamma, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane [...]
Zc3hav1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110550Zinc finger CCCH-type antiviral protein 1; Antiviral protein which inhibits the replication of viruses by recruiting the cellular RNA degradation machineries to degrade the viral mRNAs. Binds to [...]
Arhgap36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110554Rho GTPase-activating protein 36; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Atp6v0a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110558V-type proton ATPase 116 kDa subunit a isoform 4; Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney. Belongs to the V-ATP [...]
Adcy5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110563Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosol [...]
Enox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110564Protein disulfide-thiol oxidoreductase; May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at t [...]
9230102O04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000110565RIKEN cDNA 9230102O04 gene.
Celf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110574CUGBP Elav-like family member 2; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability [...]
Slc25a14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110586Brain mitochondrial carrier protein 1; Participates in the mitochondrial proton leak measured in brain mitochondria; Belongs to the mitochondrial carrier (TC 2.A.29) family.
Proser2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110592Proline and serine-rich protein 2.
Dcc protein networkhttps://string-db.org/network/10090.ENSMUSP00000110593Netrin receptor DCC; Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with U [...]
Elf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110608ETS-related transcription factor Elf-4; Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor gene [...]
Stard6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110609StAR-related lipid transfer protein 6; May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols (By similarity).
Kalrn protein networkhttps://string-db.org/network/10090.ENSMUSP00000110611Kalirin; Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, thr [...]
Luc7l protein networkhttps://string-db.org/network/10090.ENSMUSP00000110627Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain; Belongs to the Luc7 family.
Tcf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110636Transcription factor 4; Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding [...]
Fam234a protein networkhttps://string-db.org/network/10090.ENSMUSP00000110639Protein FAM234A.
Cnot4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110645CCR4-NOT transcription complex subunit 4; Has E3 ubiquitin ligase activity, promoting ubiquitination and degradation of target proteins. Involved in activation of the JAK/STAT pathway. Catalyzes [...]
Optn protein networkhttps://string-db.org/network/10090.ENSMUSP00000110648Optineurin; Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi [...]
Xpnpep2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110652Xaa-Pro aminopeptidase 2; Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the me [...]
Cyren protein networkhttps://string-db.org/network/10090.ENSMUSP00000110658Cell cycle regulator of non-homologous end joining; Cell-cycle-specific inhibitor of classical non-homologous end joining (NHEJ) of DNA double-strand break (DSB) repair during the S and G2 phases [...]
Ucma protein networkhttps://string-db.org/network/10090.ENSMUSP00000110662Unique cartilage matrix-associated protein C-terminal fragment; May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of f [...]
Lman2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000110663VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity).
Agbl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110668Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generat [...]
Cald1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110678Caldesmon 1.
Tmub1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110685Transmembrane and ubiquitin-like domain-containing protein 1; Involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR (By similarity). Involved in positive regulati [...]
Robo3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110690Roundabout homolog 3; Thought to be involved during neural development in axonal navigation at the ventral midline of the neural tube. In spinal chord development plays a role in guiding commissu [...]
Muc13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110696Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.
Dcaf12l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110709DDB1- and CUL4-associated factor 12-like protein 2; Belongs to the WD repeat DCAF12 family.
Tenm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110711Teneurin C-terminal-associated peptide; Involved in neural development, regulating the establishment of proper connectivity within the nervous system. May function as a cellular signal transducer [...]
Stag2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110725Cohesin subunit SA-2; Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring [...]
Rpl35a protein networkhttps://string-db.org/network/10090.ENSMUSP0000011072860S ribosomal protein L35a; Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator a [...]
Abcb8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110729Mitochondrial potassium channel ATP-binding subunit; ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane (By similarity). Together with CCDC51/M [...]
Ei24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110738Etoposide-induced protein 2.4; Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity).
Acbd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110741Acyl-CoA-binding domain-containing protein 7; Binds medium- and long-chain acyl-CoA esters.
Plxna4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110748Plexin-A4; Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Cla [...]
Oacyl protein networkhttps://string-db.org/network/10090.ENSMUSP00000110749O-acyltransferase like protein; Belongs to the acyltransferase 3 family.
Fam171a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110751Family with sequence similarity 171, member A1.
Iqcg protein networkhttps://string-db.org/network/10090.ENSMUSP00000110752Dynein regulatory complex protein 9; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the dis [...]
Hyls1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110762Hydrolethalus syndrome protein 1 homolog; Plays a role in ciliogenesis. Belongs to the HYLS1 family.
Cypt15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110767Cysteine-rich perinuclear theca 15.
Muc20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110769Mucin-20; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS path [...]
Cul4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000110771Cullin-4B; Core component of multiple cullin-RING-based E3 ubiquitin- protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The func [...]
Tnk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110777Activated CDC42 kinase 1; Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Trans [...]
Kmt2e protein networkhttps://string-db.org/network/10090.ENSMUSP00000110781Inactive histone-lysine N-methyltransferase 2E; Associates with chromatin regions downstream of transcriptional start sites of active genes and thus regulates gene transcription (By similarity). [...]
Tm4sf19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110802Transmembrane 4 L six family member 19.
Rhox10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110803Reproductive homeobox on X chromosome 10.
Ubxn7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110804UBX domain-containing protein 7; Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitinati [...]
Rhox7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000110809Reproductive homeobox 7B.
Tmem209 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110813Transmembrane protein 209.
Rhox2h protein networkhttps://string-db.org/network/10090.ENSMUSP00000110816Reproductive homeobox 2H.
Nrros protein networkhttps://string-db.org/network/10090.ENSMUSP00000110817Transforming growth factor beta activator LRRC33; Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activ [...]
Rhox4g protein networkhttps://string-db.org/network/10090.ENSMUSP00000110820Reproductive homeobox 4G.
Cep19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110822Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19 [...]
Rhox2g protein networkhttps://string-db.org/network/10090.ENSMUSP00000110823Reproductive homeobox 2G.
Rhox4f protein networkhttps://string-db.org/network/10090.ENSMUSP00000110824Reproductive homeobox 4F.
Rhox2f protein networkhttps://string-db.org/network/10090.ENSMUSP00000110827Reproductive homeobox 2F.
Rhox2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000110833Reproductive homeobox 2D.
Telo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110835Telomere length regulation protein TEL2 homolog; Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kin [...]
Rhox4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000110837Reproductive homeobox 4C.
Rhox2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000110844Reproductive homeobox 2C.
Rhox2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000110845Reproductive homeobox 2B.
Rhox4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000110848Reproductive homeobox on X chromosome 4.
Rhox3e protein networkhttps://string-db.org/network/10090.ENSMUSP00000110852Reproductive homeobox 3E.
Rhox3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000110857Reproductive homeobox 3A.
Nrf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110860Nuclear respiratory factor 1; Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth an [...]
Rhox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110865Reproductive homeobox 1.
Napepld protein networkhttps://string-db.org/network/10090.ENSMUSP00000110872N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D; Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the g [...]
Zbtb44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110877Zinc finger and BTB domain-containing protein 44.
Bdh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110882D-beta-hydroxybutyrate dehydrogenase, mitochondrial.
Rpl39 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011088660S ribosomal protein L39; Belongs to the eukaryotic ribosomal protein eL39 family.
Sept6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110894Septin-6; Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 [...]
Ahcyl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110897Putative adenosylhomocysteinase 3; May regulate the electrogenic sodium/bicarbonate cotransporter SLC4A4 activity and Mg(2+)-sensitivity. On the contrary of its homolog AHCYL1, does not regulate [...]
Opcml protein networkhttps://string-db.org/network/10090.ENSMUSP00000110898Opioid-binding protein/cell adhesion molecule-like.
Col19a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110899Collagen alpha-1(XIX) chain; May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal myogenesis in the developing esophagus. May play a role in or [...]
Ccdc146 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110900Coiled-coil domain-containing 146.
Tnpo3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110906Transportin-3; Importin, which transports target proteins into the nucleus. Specifically mediates the nuclear import of splicing factor serine/arginine (SR) proteins, such as RBM4, SFRS1 and SFRS [...]
Zcchc12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110911Zinc finger CCHC domain-containing protein 12; Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMA [...]
Tmem60 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110914Transmembrane protein 60.
Gm1110 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110916Beta-galactosidase.
Csf1r protein networkhttps://string-db.org/network/10090.ENSMUSP00000110923Macrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferat [...]
Fam71f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110941Family with sequence similarity 71, member F2.
Kcnq5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110955Potassium voltage-gated channel subfamily KQT member 5; Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium condu [...]
Trp63 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110965Tumor protein 63; Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibit [...]
Klhl13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110974Kelch-like protein 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin [...]
Zfp800 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110975Zinc finger protein 800; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Grm8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110978Metabotropic glutamate receptor 8; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G protein [...]
Pot1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000110986Protection of telomeres protein 1; Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. Is a component of the double-stranded t [...]
Prkcsh protein networkhttps://string-db.org/network/10090.ENSMUSP00000110987Glucosidase 2 subunit beta; Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precurs [...]
Zfp182 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110989Zinc finger protein 182; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Ccdc151 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110993Coiled-coil domain-containing protein 151; Ciliary protein involved in outer dynein arm assembly and required for motile cilia function.
Eif4a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110998Eukaryotic initiation factor 4A-II; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current mod [...]
Timp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000110999Metalloproteinase inhibitor 1; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them b [...]
Crisp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111001Cysteine-rich secretory protein 4; Belongs to the CRISP family.
Tmem243 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111022Transmembrane protein 243, mitochondrial.
Slc12a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111023Solute carrier family 12 member 2; Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume; Belong [...]
Rbm10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111032RNA-binding protein 10; Not known. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity). May bind to specific miRNA hairpins (By similarity) [...]
Rundc3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000111036RUN domain-containing protein 3B.
Cped1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111041Cadherin-like and PC-esterase domain-containing 1.
Jade3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111042Protein Jade-3; Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetyl [...]
Ccnf protein networkhttps://string-db.org/network/10090.ENSMUSP00000111048Cyclin-F; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 [...]
Ankrd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111054Ankyrin repeat domain-containing protein 7.
Slco5a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111062Solute carrier organic anion transporter family member.
Steap4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111081Metalloreductase STEAP4; Integral membrane protein that functions as NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound o [...]
Steap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111086Metalloreductase STEAP2; Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Belongs to the STEAP family.
Ap1m2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111093AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate t [...]
Thpo protein networkhttps://string-db.org/network/10090.ENSMUSP00000111097Thrombopoietin; Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. [...]
Cask protein networkhttps://string-db.org/network/10090.ENSMUSP00000111098Peripheral plasma membrane protein CASK; Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and [...]
Gtpbp10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111101GTP-binding protein 10; May be involved in the ribosome maturation process. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
Met protein networkhttps://string-db.org/network/10090.ENSMUSP00000111103Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates m [...]
Eif4g1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111120Eukaryotic translation initiation factor 4 gamma 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary [...]
Tes protein networkhttps://string-db.org/network/10090.ENSMUSP00000111127Testin; Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act a [...]
Foxp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111137Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal an [...]
Raver1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111150Ribonucleoprotein PTB-binding 1; Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually excl [...]
Zglp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111157GATA-type zinc finger protein 1; Transcriptional repressor that plays a central role in somatic cells of the gonad and is required for germ cell development. Able to repress GATA transcription fa [...]
Gm20815 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111158Predicted gene, 20815.
Phf14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111173PHD finger protein 14.
Bcor protein networkhttps://string-db.org/network/10090.ENSMUSP00000111175BCL-6 corepressor; Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA- binding proteins such as BCL6 and MLLT3. This [...]
Eef1akmt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111184EEF1A lysine methyltransferase 4; Protein-lysine methyltransferase that efficiently catalyzes three successive methylations on 'Lys-36' in eukaryotic translation elongation factor 1 alpha (EEF1A1 [...]
Mid1ip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111186Mid1-interacting protein 1; Plays a role in the regulation of lipogenesis in liver. Up- regulates ACACA enzyme activity. Required for efficient lipid biosynthesis, including triacylglycerol, diac [...]
Fam133b protein networkhttps://string-db.org/network/10090.ENSMUSP00000111189Protein FAM133B; Belongs to the FAM133 family.
Zfp944 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111197Zinc finger protein 944.
Col28a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111199Collagen alpha-1(XXVIII) chain; May act as a cell-binding protein; Belongs to the VWA-containing collagen family.
Asns protein networkhttps://string-db.org/network/10090.ENSMUSP00000111204Asparagine synthetase [glutamine-hydrolyzing].
Zfp846 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111219Zinc finger protein 846.
Dync1i1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111221Cytoplasmic dynein 1 intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargo [...]
Yeats2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111222YEATS domain-containing protein 2; Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and bind [...]
Zfp426 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111224Zinc finger protein 426; May be involved in transcriptional regulation.
Nr3c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111229Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitocho [...]
Lix1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111239Protein limb expression 1 homolog; Belongs to the LIX1 family.
Sgce protein networkhttps://string-db.org/network/10090.ENSMUSP00000111240Epsilon-sarcoglycan; Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Ufd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111241Ubiquitin recognition factor in ER-associated degradation protein 1; Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary compl [...]
Deup1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111256Deuterosome assembly protein 1; Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole ampli [...]
Tango2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111291Transport and Golgi organization 2 homolog.
Suv39h1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111300Histone-lysine N-methyltransferase SUV39H1; Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation [...]
Trmt2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000111304tRNA (uracil-5-)-methyltransferase homolog A.
Ranbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111309Ran-specific GTPase-activating protein; Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation o [...]
Pqbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111318Polyglutamine-binding protein 1; Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innat [...]
Pcdha11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111321Protocadherin alpha 11.
Pcdha11-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111322Protocadherin alpha-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Pcdha9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111323Protocadherin alpha-9; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Gm42416 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111325Predicted gene, 37013.
Pcdha2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111326Protocadherin alpha 2.
Slc35a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111327UDP-galactose translocator; Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function.
Otud5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111330OTU domain-containing protein 5; Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I int [...]
Gripap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111339GRIP1-associated protein 1; Regulates the endosomal recycling back to the neuronal plasma membrane, possibly by connecting early and late recycling endosomal domains and promoting segregation of [...]
E230025N22Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000111346Riken cDNA E230025N22 gene.
Aifm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111349Apoptosis-inducing factor 3; Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential (By similarity).
Magix protein networkhttps://string-db.org/network/10090.ENSMUSP00000111359PDZ domain-containing protein MAGIX.
Nrg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111378Pro-neuregulin-2, membrane-bound isoform; Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine [...]
Psd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111381PH and SEC7 domain-containing protein 2; Belongs to the PSD family.
Cacna1f protein networkhttps://string-db.org/network/10090.ENSMUSP00000111391Voltage-dependent L-type calcium channel subunit alpha-1F; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of c [...]
Tmem173 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111393Stimulator of interferon genes protein; Facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon (I [...]
Gucy1a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111398Guanylate cyclase 1, soluble, alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Foxp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111405Forkhead box protein P3, C-terminally processed; Transcriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg). Plays an essential role in ma [...]
Clcn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111412H(+)/Cl(-) exchange transporter 5; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosom [...]
Ttll2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111413Probable tubulin polyglutamylase TTLL2; Probable tubulin polyglutamylase that forms polyglutamate side chains on tubulin. Probably acts when complexed with other proteins; Belongs to the tubulin- [...]
Ccnb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111418G2/mitotic-specific cyclin-B3; Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via t [...]
Ube2v2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111443Ubiquitin-conjugating enzyme E2 variant 2; Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked [...]
Synj2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111457Synaptojanin-2; Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis (By simila [...]
Arid1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000111463AT-rich interactive domain-containing protein 1B; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component [...]
Nox3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111466NADPH oxidase 3; NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline st [...]
Ammecr1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000111475AMMECR1-like protein.
Pik3c3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111479Phosphatidylinositol 3-kinase catalytic subunit type 3; Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to [...]
Celf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111483CUGBP Elav-like family member 4; RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre- mRNA that are subject to tissu [...]
Tpgs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111484Tubulin polyglutamylase complex subunit 2.
Dtna protein networkhttps://string-db.org/network/10090.ENSMUSP00000111498Dystrobrevin alpha; Involved in synapse maturation and required for normal muscle function.
Glyr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111510Putative oxidoreductase GLYR1; Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation. Facilitates Pol II transcription through nucleosomes (By similarity). [...]
Rbbp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111527DNA endonuclease RBBP8; Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in DNA-end resection, the first step of double-strand break (DSB) repair through the homologous recombi [...]
Mpp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111535MAGUK p55 subfamily member 7; Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein c [...]
Uba1y protein networkhttps://string-db.org/network/10090.ENSMUSP00000111560Ubiquitin-like modifier-activating enzyme 1 Y; Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cystein [...]
ENSMUSP00000111568 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111568annotation not available
LOC100862220 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111571Predicted gene, 20878.
Fam205a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111576Mus musculus family with sequence similarity 205, member A2 (Fam205a2), transcript variant 2, mRNA.
Tmlhe protein networkhttps://string-db.org/network/10090.ENSMUSP00000111624Trimethyllysine dioxygenase, mitochondrial; Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML); Belongs to the gamma-BBH/TMLD family.
Esrp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111639Epithelial splicing regulatory protein 2; mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelia [...]
Fads3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111659Fatty acid desaturase 3; Acts as a methyl-end fatty acyl coenzyme A (CoA) desaturase that introduces a cis double bond between the preexisting double bond and the terminal methyl group of the fat [...]
Rnf186 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111780E3 ubiquitin-protein ligase RNF186; E3 ubiquitin protein ligase that is part of an apoptotic signaling pathway activated by endoplasmic reticulum stress. In that process, stimulates the expressio [...]
Eef1akmt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111939EEF1A lysine methyltransferase 3; Protein-lysine methyltransferase that selectively methylates EEF1A1 and EEF1A2 at 'Lys-165' in an aminoacyl-tRNA and GTP-dependent manner. EEF1A1 methylation by [...]
Arl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111942ADP-ribosylation factor-like protein 1; GTP-binding protein. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus (By similarity).
Hk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111946Hexokinase-1; Catalyzes the phosphorylation of various hexoses, such as D- glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glu [...]
Tnfrsf9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111961Tumor necrosis factor receptor superfamily member 9; Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
Map7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111963Ensconsin; Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with micro [...]
Stk40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000111990Serine/threonine-protein kinase 40; May be a negative regulator of NF-kappa-B and p53-mediated gene transcription; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Tctex1d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112019Tctex1 domain-containing protein 1.
Slc25a51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112044Solute carrier family 25 member 51.
Xylt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112052Xylosyltransferase 2; Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to [...]
Zfp628 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112058Zinc finger protein 628; Transcription activator. Binds DNA on GT-box consensus sequence 5'-TTGGTT-3'.
Ctc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112063CST complex subunit CTC1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication [...]
Adprm protein networkhttps://string-db.org/network/10090.ENSMUSP00000112064Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase; Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP- glucose. [...]
Cstf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112076Cleavage stimulation factor subunit 1; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity). May be responsible for the interaction [...]
Sh3bp5l protein networkhttps://string-db.org/network/10090.ENSMUSP00000112077SH3 domain-binding protein 5-like; Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
Zfp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112079Zinc finger protein 2; Probable transcription factor involved in neuronal differentiation and/or phenotypic maintenance.
Rpn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112081Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Ma [...]
Rcor1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112089REST corepressor 1; Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/ [...]
Cfap61 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112099Cilia- and flagella-associated protein 61; May regulate cilium motility through its role in the assembly of the axonemal radial spokes.
Hnrnpk protein networkhttps://string-db.org/network/10090.ENSMUSP00000112104Heterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particula [...]
Hdac7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112110Histone deacetylase 7; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic rep [...]
Ctu2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112113Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with [...]
Mthfsd protein networkhttps://string-db.org/network/10090.ENSMUSP00000112116Methenyltetrahydrofolate synthase domain-containing protein.
Trmt5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112121tRNA (guanine(37)-N1)-methyltransferase; Involved in mitochondrial tRNA methylation (By similarity). Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not d [...]
Zkscan3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112135Zinc finger protein with KRAB and SCAN domains 3; Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses [...]
Ahr protein networkhttps://string-db.org/network/10090.ENSMUSP00000112137Aryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemi [...]
Snap23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112138Synaptosomal-associated protein 23; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
Hpca protein networkhttps://string-db.org/network/10090.ENSMUSP00000112145Neuron-specific calcium-binding protein hippocalcin; Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels. May also play a role in cyclic-nucleotid [...]
Cyth3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112157Cytohesin-3; Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization.
Mphosph8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112170M-phase phosphoprotein 8; Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic r [...]
Trappc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112195Trafficking protein particle complex subunit 2; Prevents ENO1-mediated transcriptional repression and antagonizes ENO1-mediated cell death. May play a role in vesicular transport from endoplasmic [...]
Wbp11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112213WW domain-binding protein 11; Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity.
Nck1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112221Cytoplasmic protein NCK1; Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2 [...]
Bex4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112226Protein BEX4; May play a role in microtubule deacetylation by negatively regulating the SIRT2 deacetylase activity toward alpha-tubulin and thereby participate to the control of cell cycle progre [...]
Chic1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112246Cysteine-rich hydrophobic domain-containing protein 1; Belongs to the CHIC family.
Trmt112 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112250Multifunctional methyltransferase subunit TRM112-like protein; Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7) po [...]
Tmprss11f protein networkhttps://string-db.org/network/10090.ENSMUSP00000112252Transmembrane protease serine 11F; Probable serine protease; Belongs to the peptidase S1 family.
Klc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112262Kinesin light chain 2; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chai [...]
Brms1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112266Breast cancer metastasis-suppressor 1 homolog; Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 [...]
Renbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000112277N-acylglucosamine 2-epimerase; Catalyzes the interconversion of N-acetylglucosamine to N- acetylmannosamine. Binds to renin forming a protein complex called high molecular weight (HMW) renin and [...]
Mrpl39 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011228339S ribosomal protein L39, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL39 family.
Mad2l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112304Mitotic spindle assembly checkpoint protein MAD2A; Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase pla [...]
Gm4907 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112313Predicted gene, EG236749.
Barx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112314Homeobox protein BarH-like 2; Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM [...]
Ndufb11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112320NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not [...]
Prr16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112338Protein Largen; Regulator of cell size that promotes cell size increase independently of mTOR and Hippo signaling pathways. Acts by stimulating the translation of specific mRNAs, including those [...]
Lmf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112340Lipase maturation factor 1; Involved in the maturation of specific proteins in the endoplasmic reticulum. Required for maturation and transport of active lipoprotein lipase (LPL) through the secr [...]
Tcp10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000112365T-complex protein 10b.
Aktip protein networkhttps://string-db.org/network/10090.ENSMUSP00000112375AKT-interacting protein; Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sortin [...]
Prxl2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000112377Peroxiredoxin-like 2A; Involved in redox regulation of the cell (By similarity). Acts as an antioxidant (By similarity). Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast different [...]
Trip4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112385Activating signal cointegrator 1; Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factor [...]
Gm21987 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112386Cytochrome c oxidase copper chaperone; Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two co [...]
Itga10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112393Integrin, alpha 10; Belongs to the integrin alpha chain family.
Lins1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112404Protein Lines homolog 1.
Slc45a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112408Membrane-associated transporter protein; Melanocyte differentiation antigen. May transport substances required for melanin biosynthesis (By similarity); Belongs to the glycoside-pentoside-hexuron [...]
Disc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112410Disrupted in schizophrenia 1 homolog; Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrica [...]
Klhl22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112412Kelch-like protein 22; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) [...]
Slc28a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112421Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
Shisa7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112423Protein shisa-7; Transmembrane protein that regulates gamma-aminobutyric acid type A receptor (GABA(A)R) trafficking, channel deactivation kinetics and pharmacology, necessary for fast inhibitory [...]
Fgfr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112430Fibroblast growth factor receptor 2; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, [...]
Syt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112432Synaptotagmin-3; Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to [...]
Tmc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112434Transmembrane channel-like protein 5; Probable ion channel; Belongs to the TMC family.
Cacna1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000112436Voltage-dependent P/Q-type calcium channel subunit alpha-1A; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of [...]
Syt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112438Synaptotagmin-2; Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties. May have a regulatory role in the membrane interactions during trafficking of synaptic vesi [...]
Palld protein networkhttps://string-db.org/network/10090.ENSMUSP00000112442Palladin; Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in [...]
Olfr380 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112462Olfactory receptor.
Plekha8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112466Pleckstrin homology domain-containing family A member 8; Cargo transport protein that is required for apical transport from the trans-Golgi network (TGN). Transports AQP2 from the trans- Golgi ne [...]
Col6a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112472Collagen alpha-4(VI) chain; Collagen VI acts as a cell-binding protein.
Gm14434 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112478Predicted gene 14434.
Ctsf protein networkhttps://string-db.org/network/10090.ENSMUSP00000112481Cathepsin F; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Pramef20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112488PRAME family member 20.
Eml2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112491Echinoderm microtubule-associated protein-like 2; Tubulin binding protein that inhibits microtubule nucleation and growth, resulting in shorter microtubules.
Zfp607b protein networkhttps://string-db.org/network/10090.ENSMUSP00000112494Zinc finger protein 607B.
Zdhhc13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112498Palmitoyltransferase ZDHHC13; Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
Atg16l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112500Autophagy-related protein 16-2; May play a role in autophagy.
Trp53bp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112508Apoptosis-stimulating of p53 protein 2; Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions with proteins such as TP53 (By similarity). Regulates p [...]
Fbxl21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112518F-box/LRR-repeat protein 21; Substrate-recognition component of the SCF(FBXL21) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the [...]
Otx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112532Homeobox protein OTX2; Transcription factor probably involved in the development of the brain and the sense organs. Can bind to the bicoid/BCD target sequence (BTS): 5'-TCTAATCCC-3'; Belongs to t [...]
Fam20b protein networkhttps://string-db.org/network/10090.ENSMUSP00000112534Glycosaminoglycan xylosylkinase; Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG cha [...]
Abca17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112538ATP-binding cassette sub-family A member 17; Promotes cholesterol efflux from sperm which renders sperm capable of fertilization. Has also been shown to decrease levels of intracellular esterifie [...]
Zfp455 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112546Zinc finger protein 455.
Sh3bp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112554SH3 domain-binding protein 2; Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase [...]
Poli protein networkhttps://string-db.org/network/10090.ENSMUSP00000112563DNA polymerase iota; Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot procee [...]
Ipmk protein networkhttps://string-db.org/network/10090.ENSMUSP00000112568Inositol polyphosphate multikinase; Inositol phosphate kinase with a broad substrate specificity. Phosphorylates inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) first to inositol 1,3,4,5-tetrakisphos [...]
Ddr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112570Epithelial discoidin domain-containing receptor 1; Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remode [...]
Golga7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000112575Golgin subfamily A member 7B; May be involved in protein transport from Golgi to cell surface; Belongs to the ERF4 family.
Kbtbd12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112581Kelch repeat and BTB domain-containing protein 12.
Oas1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000112584Inactive 2'-5' oligoadenylate synthetase 1C; Does not have 2'-5'-OAS activity, but can bind double- stranded RNA; Belongs to the 2-5A synthase family.
Lmtk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112592Serine/threonine-protein kinase LMTK3; Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT- [...]
Sirt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112595NAD-dependent protein deacetylase sirtuin-1; NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of s [...]
Slc5a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112597Sodium/glucose cotransporter 2; Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucos [...]
Tbrg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112600Transforming growth factor beta regulator 1; Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require eithe [...]
Cep135 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112602Centrosomal protein of 135 kDa; Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Required for the targeting of centriole sate [...]
Emcn protein networkhttps://string-db.org/network/10090.ENSMUSP00000112603Endomucin; Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and [...]
Ano1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112616Anoctamin-1; Calcium-activated chloride channel (CaCC) which plays an important role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the i [...]
Crybb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112618Beta-crystallin B3, N-terminally processed; Crystallins are the dominant structural components of the vertebrate eye lens.
Usf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112620Upstream transcription factor family member 3.
Isg20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112621Interferon-stimulated gene 20 kDa protein; Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antivira [...]
Hcrtr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112630Orexin receptor type 1; Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Triggers an increase in cytoplasmic Ca(2+) levels in response [...]
Mapk1ip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112631MAPK-interacting and spindle-stabilizing protein; Involved in the maintenance of the spindle integrity during the cytostatic factor (CSF) arrest of oocytes.
Ube4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000112632Ubiquitin conjugation factor E4 A; Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the [...]
Slc18b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112634MFS-type transporter SLC18B1; Belongs to the major facilitator superfamily.
Maml3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112637Mastermind-like transcriptional coactivator 3.
Pef1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112638Peflin; Calcium-binding protein that acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protein complexes in response to calcium. Together with PDCD6, acts as calcium-d [...]
Naf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112640H/ACA ribonucleoprotein complex non-core subunit NAF1; RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs c [...]
Slc48a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112644Heme transporter HRG1; Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment. Belongs to the HRG family.
Prss36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112659Polyserase-2; Serine protease. Hydrolyzes the peptides N-t-Boc-Gln-Ala-Arg- AMC and N-t-Boc-Gln-Gly-Arg-AMC and, to a lesser extent, N-t-Boc-Ala- Phe-Lys-AMC and N-t-Boc-Val-Leu-Lys-AMC. Has a pr [...]
Reep1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112662Receptor expression-enhancing protein 1; Required for endoplasmic reticulum (ER) network formation, shaping and remodeling; it links ER tubules to the cytoskeleton. May also enhance the cell surf [...]
Akr1c14 protein networkhttps://string-db.org/network/10090.ENSMUSP000001126643-alpha-hydroxysteroid dehydrogenase type 1.
Ecm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112665Extracellular matrix protein 1; Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. [...]
Akr1c19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112666Aldo-keto reductase family 1, member C19.
Tsks protein networkhttps://string-db.org/network/10090.ENSMUSP00000112673Testis-specific serine kinase substrate; May play a role in testicular physiology, most probably in the process of spermatogenesis or spermatid development.
Ptpn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112675Tyrosine-protein phosphatase non-receptor type 2; Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also [...]
Nap1l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112677Nucleosome assembly protein 1-like 2; Acidic protein which may be involved in interactions with other proteins or DNA.
Sult1b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112679Sulfotransferase family cytosolic 1B member 1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurot [...]
Bdh2 protein networkhttps://string-db.org/network/10090.ENSMUSP000001126833-hydroxybutyrate dehydrogenase type 2; Dehydrogenase that mediates the formation of 2,5- dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial entero [...]
Slc29a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112685Equilibrative nucleoside transporter 3; Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates transport of adenine, adenosine and uridine (By si [...]
Samd9l protein networkhttps://string-db.org/network/10090.ENSMUSP00000112688Sterile alpha motif domain-containing protein 9-like; May be involved in endosome fusion. Mediates down-regulation of growth factor signaling via internalization of growth factor receptors.
Defb28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112697Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
Mybpc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112699Myosin-binding protein C, slow-type.
Dnajb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112703DnaJ homolog subfamily B member 3; May operate as a co-chaperone of the male germ cell- and haploid stage-specific Hsp70 proteins.
Chpt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112708Cholinephosphotransferase 1; Catalyzes phosphatidylcholine biosynthesis from CDP-choline. It thereby plays a central role in the formation and maintenance of vesicular membranes (By similarity).
Kif2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000112715Kinesin-like protein KIF2A; Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progre [...]
Gk5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112717Putative glycerol kinase 5.
Wdr31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112719WD repeat-containing protein 31.
Farp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112725FERM, ARHGEF and pleckstrin domain-containing protein 2; Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity (and. Plays a role in the response t [...]
Bco2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112727Beta,beta-carotene 9',10'-oxygenase; Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta- ionone. Besides beta-carotene, l [...]
Abca16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112736ATP-binding cassette, sub-family A (ABC1), member 16.
Pomgnt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112751Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1; Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoprotein [...]
Btc protein networkhttps://string-db.org/network/10090.ENSMUSP00000112765Probetacellulin; Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
Tent4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000112766Terminal nucleotidyltransferase 4B; Terminal nucleotidyltransferase that catalyzes preferentially the transfert of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail lead [...]
Sycn protein networkhttps://string-db.org/network/10090.ENSMUSP00000112770Syncollin; Functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. May have a pore-forming activity on membranes and regulate exocytosis in o [...]
Gm6121 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112771Predicted gene 6121.
Robo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112776Roundabout homolog 2; Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the n [...]
Zbtb9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112778Zinc finger and BTB domain-containing protein 9; May be involved in transcriptional regulation.
Mrps17 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011277928S ribosomal protein S17, mitochondrial; Belongs to the universal ribosomal protein uS17 family.
Kif3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000112782Kinesin-like protein KIF3A; Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. [...]
Mup12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112787Major urinary protein 1; Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females.
Zwilch protein networkhttps://string-db.org/network/10090.ENSMUSP00000112790Protein zwilch homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 comple [...]
Synpo2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000112792Synaptopodin 2-like protein; Actin-associated protein that may play a role in modulating actin-based shape; Belongs to the synaptopodin family.
Klra5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112795Killer cell lectin-like receptor 5; Receptor on natural killer (NK) cells for class I MHC.
Itih4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112798Inter alpha-trypsin inhibitor, heavy chain 4; Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration.
Nfyc protein networkhttps://string-db.org/network/10090.ENSMUSP00000112810Nuclear transcription factor Y subunit gamma; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the prom [...]
Pttg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112815Securin; Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, [...]
Rlim protein networkhttps://string-db.org/network/10090.ENSMUSP00000112820E3 ubiquitin-protein ligase RLIM; E3 ubiquitin-protein ligase that acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradat [...]
Card6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112833Caspase recruitment domain family, member 6.
Creb3l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112836Processed cyclic AMP-responsive element-binding protein 3-like protein 3; Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target gene [...]
Scn5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000112838Sodium channel protein type 5 subunit alpha; This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the [...]
S100a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112843Protein S100-A9; S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, a [...]
1700034E13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000112845RIKEN cDNA 1700034E13 gene.
Scamp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112846Secretory carrier-associated membrane protein 3; Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface; Belongs to the SCAMP family.
Plagl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112847Pleiomorphic adenoma gene-like 1.
Lsg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112860Large subunit GTPase 1 homolog; GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subun [...]
Naip6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112867Baculoviral IAP repeat-containing protein 1f; Sensor component of the NLRC4 inflammasome that specifically recognizes and binds flagellin from pathogenic bacteria. Association of pathogenic bacte [...]
Ncapg protein networkhttps://string-db.org/network/10090.ENSMUSP00000112871Non-SMC condensin I complex, subunit G.
Mthfd1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000112897Monofunctional C1-tetrahydrofolate synthase, mitochondrial; May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon fol [...]
Rnft2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112903RING finger and transmembrane domain-containing protein 2.
Gm20489 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112905Predicted gene 20489.
Etv3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112915ETS translocation variant 3; Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferati [...]
Acp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112922Testicular acid phosphatase; May dephosphorylate receptor tyrosine-protein kinase ERBB4 and inhibits its ligand-induced proteolytic cleavage. May play a role in odontogenesis; Belongs to the hist [...]
Mgst1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112923Microsomal glutathione S-transferase 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Zfp617 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112926Zinc finger protein 617.
Dpysl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112928Dihydropyrimidinase-related protein 3; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse a [...]
Spock3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112930Testican-3; May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion (By simil [...]
Ankrd24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112932Ankyrin repeat domain-containing protein 24.
Magi3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112934Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Co [...]
Golga7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112935Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS (By similarity).
Vps8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112937Vacuolar protein sorting-associated protein 8 homolog; Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the puta [...]
Pld3 protein networkhttps://string-db.org/network/10090.ENSMUSP000001129425'-3' exonuclease PLD3; 5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentra [...]
Egfem1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112943EGF-like and EMI domain-containing protein 1.
Rtkn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112946Rhotekin-2; May play an important role in lymphopoiesis.
Ppil3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112947Peptidyl-prolyl cis-trans isomerase-like 3; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved [...]
Prpf39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112953Pre-mRNA-processing factor 39; Involved in pre-mRNA splicing.
Nrip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112959Nuclear receptor-interacting protein 1; Modulates transcriptional repression by nuclear hormone receptors such as NR2C1, thyroid hormone receptor and retinoic acid receptor/RARA. Essential for cu [...]
Taok2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112963Serine/threonine-protein kinase TAO2; Serine/threonine-protein kinase involved in different processes such as membrane blebbing and apoptotic bodies formation DNA damage response and MAPK14/p38 M [...]
Asb15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112965Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquit [...]
Prss53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112972Serine protease 53; In vitro can degrade the fibrinogen alpha chain of as well as pro-urokinase-type plasminogen activator; Belongs to the peptidase S1 family.
Sgpl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112975Sphingosine-1-phosphate lyase 1; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide pro [...]
Mrpl1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011297739S ribosomal protein L1, mitochondrial.
Casz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112978Zinc finger protein castor homolog 1; Transcription factor involved in vascular assembly and morphogenesis through direct transcriptional regulation of EGFL7.
Gm4985 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112982Predicted gene 4985.
Abhd17c protein networkhttps://string-db.org/network/10090.ENSMUSP00000112988Alpha/beta hydrolase domain-containing protein 17C; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards DLG4/PSD95. Belongs to the AB hydro [...]
Rasa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000112998Ras GTPase-activating protein 3; Inhibitory regulator of the Ras-cyclic AMP pathway. May bind inositol tetrakisphosphate (IP4).
Atp5pb protein networkhttps://string-db.org/network/10090.ENSMUSP00000113022ATP synthase F(0) complex subunit B1, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the [...]
Gpr174 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113032Probable G-protein coupled receptor 174; Putative receptor for purines coupled to G-proteins.
Dmrtc1c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113033DMRT-like family C1c1.
Sept8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113038Septin-8; Filament-forming cytoskeletal GTPase (By similarity). May play a role in platelet secretion (By similarity). Seems to participate in the process of SNARE complex formation in synaptic v [...]
Wwtr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113040WW domain-containing transcription regulator protein 1; Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ [...]
Rhpn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113042Rhophilin-1; Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules; Belongs to the RHPN [...]
Hagh protein networkhttps://string-db.org/network/10090.ENSMUSP00000113051Hydroxyacylglutathione hydrolase, mitochondrial; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid; Belongs to the metallo-beta-lactama [...]
Adal protein networkhttps://string-db.org/network/10090.ENSMUSP00000113052Adenosine deaminase-like protein; Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine. [...]
Best1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113053Bestrophin-1; Forms calcium-sensitive chloride channels. Permeable to bicarbonate (By similarity); Belongs to the bestrophin family.
Il24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113064Interleukin-24; Has antiproliferative properties on melanoma cells and may contribute to terminal cell differentiation.
Msn protein networkhttps://string-db.org/network/10090.ENSMUSP00000113071Moesin; Ezrin-radixin-moesin (ERM) family protein that connects the actin cytoskeleton to the plasma membrane and thereby regulates the structure and function of specific domains of the cell cort [...]
Smim11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113086Small integral membrane protein 11A; Belongs to the SMIM11 family.
Iffo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113088Intermediate filament family orphan 1.
Tmem132c protein networkhttps://string-db.org/network/10090.ENSMUSP00000113090Transmembrane protein 132C.
Lilra5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113091Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5.
Nlrp4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000113095NACHT, LRR and PYD domains-containing protein 4B; May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound rec [...]
Orai1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113097Calcium release-activated calcium channel protein 1; Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and cha [...]
Lemd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113103Inner nuclear membrane protein Man1; Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced ce [...]
Rerg protein networkhttps://string-db.org/network/10090.ENSMUSP00000113105Ras-related and estrogen-regulated growth inhibitor; Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP (By similarity); Belongs to the small GTPase s [...]
Nkain3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113113Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3; Belongs to the NKAIN family.
Spock2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113115Testican-2; May participate in diverse steps of neurogenesis. Binds calcium (By similarity).
Stt3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000113116Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A; Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined gl [...]
Tex55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113120Testis-specific expressed protein 55.
Apoc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113126Apolipoprotein C-III; Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Int [...]
Capn11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113132Calpain-11; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction; Belongs to the peptidase [...]
Gm14295 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113133Predicted gene 14295.
Abhd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113137Phospholipase ABHD3; Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 [...]
Tafa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113152Chemokine-like protein TAFA-1; Regulatory factor which is ligand for GPR1 and is involved in the modulation of neural stem-cell proliferation and differentiation.
Gm2012 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113154Predicted gene 2012.
Epp13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113155Epididymal protein 13.
Cbx5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113157Chromobox protein homolog 5; Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded [...]
Acyp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113161Acylphosphatase-1; Its physiological role is not yet clear; Belongs to the acylphosphatase family.
Ankle1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113162Ankyrin repeat and LEM domain-containing protein 1; Endonuclease that probably plays a role in the DNA damage response and DNA repair.
Stim2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113174Stromal interaction molecule 2; Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive C [...]
Slc26a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113185Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate (By similarity). B [...]
Pxylp1 protein networkhttps://string-db.org/network/10090.ENSMUSP000001132102-phosphoxylose phosphatase 1; Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosa [...]
Gm10639 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113211Glutathione S-transferase.
Depdc1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000113216DEP domain-containing protein 1A; May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by [...]
Matk protein networkhttps://string-db.org/network/10090.ENSMUSP00000113221Megakaryocyte-associated tyrosine-protein kinase; Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC- family members in [...]
Lias protein networkhttps://string-db.org/network/10090.ENSMUSP00000113228Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent [...]
Mmp27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113231Matrix metallopeptidase 27.
Kcnmb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113234Calcium-activated potassium channel subunit beta-2; Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, [...]
Fam160a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113235Protein FAM160A1; Belongs to the UPF0518 family.
Pate2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113239Prostate and testis expressed protein 2.
Siglecf protein networkhttps://string-db.org/network/10090.ENSMUSP00000113245Sialic acid-binding Ig-like lectin 5; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3-linked sialic acid. The sialic acid recogn [...]
Uspl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113247SUMO-specific isopeptidase USPL1; SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for SUMO2 and SUMO3 which it cleaves more e [...]
Prr14l protein networkhttps://string-db.org/network/10090.ENSMUSP00000113259Proline-rich 14-like.
Gemin7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113266Gem-associated protein 7; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important r [...]
G2e3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113270G2/M phase-specific E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers [...]
Arsk protein networkhttps://string-db.org/network/10090.ENSMUSP00000113274Arylsulfatase K.
Hecw2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113283E3 ubiquitin-protein ligase HECW2; E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. Involved in the regula [...]
Afap1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113286Actin filament-associated protein 1-like 1; May be involved in podosome and invadosome formation.
Ankrd60 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113291Ankyrin repeat domain 60.
Cdkl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113303Cyclin-dependent kinase-like 3.
Pex1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113304Peroxisome biogenesis factor 1; Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase co [...]
Dusp13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113305Dual specificity protein phosphatase 13 isoform B; Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro. Exhibits intrinsic phosphatase activi [...]
Mterf1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000113306Transcription termination factor 1a, mitochondrial; Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream o [...]
Tbc1d10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000113307TBC1 domain family member 10B; Acts as GTPase-activating protein for RAB3A, RAB22A, RAB27A, AND RAB35. Does not act on RAB2A and RAB6A (By similarity).
Synj1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113308Synaptojanin-1; Phosphatase that acts on various phosphoinositides, including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)- bisphosphate and phosphatidylinositol (3,4,5)-trisphosp [...]
Wdr66 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113309Cilia- and flagella-associated protein 251; Involved in spermatozoa motility (By similarity). May also regulate cilium motility through its role in the assembly of the axonemal radial spokes (By [...]
Mrgpra2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000113310Mas-related G-protein coupled receptor member A2; Orphan receptor. May be a receptor for RFamide-family neuropeptides such as NPFF and NPAF, which are analgesic in vivo. May regulate nociceptor f [...]
Nrip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113317Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors, such as NR1F2.
Ccsap protein networkhttps://string-db.org/network/10090.ENSMUSP00000113319Centriole, cilia and spindle-associated protein; Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with pol [...]
Rab3d protein networkhttps://string-db.org/network/10090.ENSMUSP00000113322Ras-related protein Rab-3D; Protein transport. Probably involved in vesicular traffic (By similarity). May be involved in the insulin-induced exocytosis of glut4-containing vesicles in adipocytes [...]
Kcnt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113333Potassium channel, subfamily T, member 2.
Csnk1e protein networkhttps://string-db.org/network/10090.ENSMUSP00000113341Casein kinase I isoform epsilon; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of p [...]
Il23r protein networkhttps://string-db.org/network/10090.ENSMUSP00000113342Interleukin-23 receptor; Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably [...]
Mrps10 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011334328S ribosomal protein S10, mitochondrial; Belongs to the universal ribosomal protein uS10 family.
Dzip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113344E3 ubiquitin-protein ligase DZIP3; E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 [...]
Ankrd50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113349Ankyrin repeat domain 50.
Cox18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113353Cytochrome c oxidase assembly protein COX18, mitochondrial; Mitochondrial membrane insertase required for the translocation of the C-terminus of cytochrome c oxidase subunit II (MT- CO2/COX2) acr [...]
Pex11b protein networkhttps://string-db.org/network/10090.ENSMUSP00000113365Peroxisomal membrane protein 11B; Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes memb [...]
Cdc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113385Cell division cycle 7-related protein kinase; Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.
Clk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113390Dual specificity protein kinase CLK2; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the sp [...]
Prkd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113395Serine/threonine-protein kinase D3; Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similar [...]
Nyap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113397Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1; Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesi [...]
Rgs20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113398Regulator of G-protein signaling 20; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds sele [...]
Car15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113400Carbonic anhydrase 15; Reversible hydration of carbon dioxide.
Nmb protein networkhttps://string-db.org/network/10090.ENSMUSP00000113407Neuromedin-B-32; Stimulates smooth muscle contraction in a manner similar to that of bombesin; Belongs to the bombesin/neuromedin-B/ranatensin family.
Apoa5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113413Apolipoprotein A-V; Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) l [...]
Dnajc5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000113414DnaJ homolog subfamily C member 5B.
Adamtsl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113424ADAMTS-like protein 4; Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis (By similarity).
Rufy2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113429RUN and FYVE domain-containing protein 2.
Cox17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113430Cytochrome c oxidase assembly protein 17, copper chaperone.
Rsl1d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113431Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.
Kcnd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113436Potassium voltage-gated channel subfamily D member 3; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I( [...]
Dpp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113441Dipeptidyl aminopeptidase-like protein 6; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no [...]
Ngrn protein networkhttps://string-db.org/network/10090.ENSMUSP00000113444Neugrin; Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitocho [...]
Ccdc186 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113457Coiled-coil domain-containing protein 186.
Dpf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113465Zinc finger protein ubi-d4; Plays an active role in transcriptional regulation by binding modified histones H3 and H4. Is a negative regulator of myeloid differentiation of hematopoietic progenit [...]
Gm49333 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113475EEF1AKMT4-ECE2 readthrough transcript protein; Converts big endothelin-1 to endothelin-1. May also have methyltransferase activity (By similarity). May play a role in amyloid- beta processing ; I [...]
Pde4d protein networkhttps://string-db.org/network/10090.ENSMUSP00000113488cAMP-specific 3',5'-cyclic phosphodiesterase 4D; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes; Belongs to the cyclic nucleotide phospho [...]
Adcy9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113498Adenylate cyclase type 9; Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein-coupled receptors. Contributes to signaling cascades [...]
Fuca2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113499Plasma alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoprote [...]
Cadm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113500Cell adhesion molecule 2; Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organ [...]
Art3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113510Ecto-ADP-ribosyltransferase 3.
Gjb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113516Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a [...]
Rab11fip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113521Rab11 family-interacting protein 3; Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'addre [...]
Vps29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113525Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective [...]
Cdh13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113527Cadherin-13; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the [...]
Phkg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113533Phosphorylase b kinase gamma catalytic chain, liver/testis isoform; Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown [...]
Fam118b protein networkhttps://string-db.org/network/10090.ENSMUSP00000113537Protein FAM118B; May play a role in Cajal bodies formation.
Crtc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113540CREB-regulated transcription coactivator 3; Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coa [...]
Syt8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113545Synaptotagmin-8; Involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Mediates Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. May mediate Ca(2+) [...]
Itga3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113556Integrin alpha-3 heavy chain; Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha- 3/beta-1 provides a docking site for F [...]
Wdr61 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113560WD repeat-containing protein 61, N-terminally processed; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulati [...]
Zfp534 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113561Zinc finger protein 534.
Ank1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113571Ankyrin-1; Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cy [...]
Slc5a4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000113582Solute carrier family 5 (neutral amino acid transporters, system A), member 4b; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Cops7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000113587COP9 signalosome complex subunit 7b; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator [...]
2610002M06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000113588Charged multivesicular body protein 1b-2; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bo [...]
Lrrc8d protein networkhttps://string-db.org/network/10090.ENSMUSP00000113603Volume-regulated anion channel subunit LRRC8D; Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cel [...]
Serpina1e protein networkhttps://string-db.org/network/10090.ENSMUSP00000113606Alpha-1-antitrypsin 1-5; Does not inhibit elastase or chymotrypsin. No target protease has been identified to date; Belongs to the serpin family.
Ccdc155 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113616Protein KASH5; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic in [...]
Spg20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113621Spartin; May be implicated in endosomal trafficking, or microtubule dynamics, or both. Participates in cytokinesis.
Adam32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113627Disintegrin and metalloproteinase domain-containing protein 32; May play a role in sperm development and fertilization This is a non-catalytic metalloprotease-like protein.
Tmc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113628Transmembrane channel-like protein 8; Probable ion channel.
Vps9d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113634VPS9 domain-containing protein 1.
Nfu1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113637NFU1 iron-sulfur cluster scaffold homolog, mitochondrial; Iron-sulfur cluster scaffold protein which can assemble [4Fe- 4S] clusters and deliver them to target proteins.
Ifitm7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113641Interferon-induced transmembrane protein 7.
4930432K21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000113651Uncharacterized protein C19orf57 homolog.
Fam104a protein networkhttps://string-db.org/network/10090.ENSMUSP00000113652Family with sequence similarity 104, member A.
Stk38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113657Serine/threonine-protein kinase 38; Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K [...]
Dyrk1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000113660Dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. May play a role in a signaling pathway [...]
Gm4631 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113670Predicted gene 4631.
Cth protein networkhttps://string-db.org/network/10090.ENSMUSP00000113672Cystathionine gamma-lyase; Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2 [...]
Celf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113675CUGBP, Elav-like family member 5.
Simc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113676SUMO-interacting motifs-containing 1.
Fam189a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113680Protein FAM189A1; Belongs to the FAM189 family.
Thsd7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000113681Thrombospondin type-1 domain-containing protein 7A, soluble form; [Thrombospondin type-1 domain-containing protein 7A]: Plays a role in actin cytoskeleton rearrangement.
Srsf11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113685Serine and arginine-rich-splicing factor 11.
Cbln2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113695Cerebellin-2; Acts as a synaptic organizer in specific subsets of neurons in the brain. Essential for long- term maintenance but not establishment of excitatory synapses.
Gtf2a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113697Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a compl [...]
Pxdn protein networkhttps://string-db.org/network/10090.ENSMUSP00000113703Peroxidasin homolog; Displays low peroxidase activity and is likely to participate in H(2)O(2) metabolism and peroxidative reactions in the cardiovascular system (By similarity). Plays a role in [...]
Dmxl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113705DmX-like protein 2; May serve as a scaffold protein for MADD and RAB3GA on synaptic vesicles of neuronal and endocrine homeostatic processes (By similarity). Plays a role in the brain as a key co [...]
Olfr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113707Olfactory receptor 1; Odorant receptor. Activated by a lily-derived aldehyde as well as other odorants. May signal through an inositol 1,4,5- trisphosphate (IP3) second messenger system (By simil [...]
Xkr6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113708XK-related protein 6; Belongs to the XK family.
Vezt protein networkhttps://string-db.org/network/10090.ENSMUSP00000113715Vezatin; Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. Required for morphogenesis of the preimplantation embryo, and for the implantation pr [...]
Dctn6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113716Dynactin subunit 6; Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
Pcf11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113717PCF11 cleavage and polyadenylation factor subunit.
Syn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113720Synapsin-3; May be involved in the regulation of neurotransmitter release and synaptogenesis. Binds ATP with high affinity and ADP with a lower affinity. This is consistent with a catalytic role [...]
Il4i1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113726L-amino-acid oxidase; Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation; Belongs to the flavin mon [...]
Slc7a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113729Cationic amino acid transporter 2; Isoform 1 functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). Isoform 2 al [...]
Dmrtc1c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113737DMRT-like family C1c1.
Mup9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113741Major urinary protein 9.
1700064H15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000113751RIKEN cDNA 1700064H15 gene.
Klhl14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113755Kelch-like protein 14.
Stmn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113759Stathmin-4; Exhibits microtubule-destabilizing activity; Belongs to the stathmin family.
Pdcd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113761Programmed cell death protein 5; May function in the process of apoptosis; Belongs to the PDCD5 family.
Ankrd42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113767Ankyrin repeat domain-containing protein 42.
Ift88 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113768Intraflagellar transport protein 88 homolog; Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic c [...]
Zfp740 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113770Zinc finger protein 740; May be involved in transcriptional regulation.
Nod2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113773Nucleotide-binding oligomerization domain-containing protein 2; Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds th [...]
Rapgef2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113778Rap guanine nucleotide exchange factor 2; Functions as a guanine nucleotide exchange factor (GEF), which activates Rap and Ras family of small GTPases by exchanging bound GDP for free GTP in a cA [...]
Tm9sf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113782Transmembrane 9 superfamily member 1; Plays an essential role in autophagy; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
Inava protein networkhttps://string-db.org/network/10090.ENSMUSP00000113785Innate immunity activator protein; Expressed in peripheral macrophages and intestinal myeloid- derived cells, is required for optimal PRR (pattern recognition receptor)-induced signaling, cytokin [...]
Aasdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000113792Beta-alanine-activating enzyme; Covalently binds beta-alanine in an ATP-dependent manner to form a thioester bond with its phosphopantetheine group and transfers it to an as yet unknown acceptor [...]
Furin protein networkhttps://string-db.org/network/10090.ENSMUSP00000113793Furin; Ubiquitous endoprotease within constitutive secretory pathways capable of cleavage at the RX(K/R)R consensus motif. Mediates processing of TGFB1, an essential step in TGF-beta-1 activation [...]
Gm49340 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113799Predicted gene, 49340.
Sel1l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113800Protein sel-1 homolog 2.
Papln protein networkhttps://string-db.org/network/10090.ENSMUSP00000113806Papilin.
Aip protein networkhttps://string-db.org/network/10090.ENSMUSP00000113807AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targetin [...]
Pld1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113810Phospholipase D1; Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulatio [...]
Chchd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113811Coiled-coil-helix-coiled-coil-helix domain-containing protein 7; Belongs to the CHCHD7 family.
4930550L24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000113812RIKEN cDNA 4930550L24 gene.
Pigg protein networkhttps://string-db.org/network/10090.ENSMUSP00000113818Phosphatidylinositol glycan anchor biosynthesis, class G.
Grm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113819Metabotropic glutamate receptor 4; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G protein [...]
Cngb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113827Cyclic nucleotide-gated channel beta 1.
Paxbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113835PAX3- and PAX7-binding protein 1; Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyl [...]
Lmo4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113840LIM domain transcription factor LMO4; Probable transcriptional factor.
S1pr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113843Sphingosine 1-phosphate receptor 5; Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of [...]
Bcl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113851B-cell lymphoma 3 protein homolog; Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p [...]
Syk protein networkhttps://string-db.org/network/10090.ENSMUSP00000113852Tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell [...]
Depdc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113862GATOR complex protein DEPDC5; As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydro [...]
Glt1d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113864Glycosyltransferase 1 domain-containing protein 1; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Rph3al protein networkhttps://string-db.org/network/10090.ENSMUSP00000113869Rab effector Noc2; Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Regulates the exocytosis of dense-core vesicles in neuroendocrine [...]
Ankef1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113881Ankyrin repeat and EF-hand domain-containing protein 1.
Rab4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000113886Ras-related protein Rab-4A; Protein transport. Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling.
Naip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113890Baculoviral IAP repeat-containing protein 1b; Sensor component of the NLRC4 inflammasome that specifically recognizes and binds type III secretion system (T3SS) rod proteins such as S.typhimurium [...]
N4bp2l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113895NEDD4-binding protein 2-like 2.
R3hcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113898R3H and coiled-coil domain-containing protein 1.
Amz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113911Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2 (By similarity).
Sgcz protein networkhttps://string-db.org/network/10090.ENSMUSP00000113912Zeta-sarcoglycan; Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. May p [...]
Zfr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113913Zinc finger RNA-binding protein 2.
Hs3st1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113919Heparan sulfate glucosamine 3-O-sulfotransferase 1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine res [...]
Anapc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113928Anaphase-promoting complex subunit 7; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G [...]
Oosp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113931Oocyte-secreted protein 2.
1700016H13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000113935Uncharacterized protein C4orf36 homolog.
Eme2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113936Probable crossover junction endonuclease EME2; Interacts with MUS81 to form a DNA structure-specific endonuclease which cleaves substrates such as 3'-flap structures.
Gapdh protein networkhttps://string-db.org/network/10090.ENSMUSP00000113942Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. G [...]
Cnpy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113944Protein canopy homolog 1.
Serpina3f protein networkhttps://string-db.org/network/10090.ENSMUSP00000113945Serine protease inhibitor A3F; Belongs to the serpin family.
Zfp868 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113952Zinc finger protein 868.
Fam167a protein networkhttps://string-db.org/network/10090.ENSMUSP00000113962Protein FAM167A; Belongs to the FAM167 (SEC) family.
Lrit1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113964Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1; Possible role in phototransduction.
Zcchc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113974Zinc finger CCHC domain-containing protein 2.
Cdon protein networkhttps://string-db.org/network/10090.ENSMUSP00000113977Cell adhesion molecule-related/down-regulated by oncogenes; Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiat [...]
Tpm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113978Tropomyosin alpha-3 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebra [...]
Ido2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113979Indoleamine 2,3-dioxygenase 2; Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism. Involved in immune regulation.
Hipk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000113998Homeodomain-interacting protein kinase 1; Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain t [...]
Klra4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114004Killer cell lectin-like receptor 4; Receptor on natural killer (NK) cells for class I MHC.
Golim4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114006Golgi integral membrane protein 4; Plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi; B [...]
Gng5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114014Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling sy [...]
Fam107a protein networkhttps://string-db.org/network/10090.ENSMUSP00000114015Actin-associated protein FAM107A; Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F- actin) dynamics. Mediates polyme [...]
Pgap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114016Post-GPI attachment to proteins factor 2; Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface (By similari [...]
Nipa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114020Magnesium transporter NIPA2; Acts as a selective Mg(2+) transporter.
Lrp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114026Low density lipoprotein receptor-related protein 3.
Ankrd29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114028Ankyrin repeat domain 29.
Olfml1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114029Olfactomedin-like 1.
AU022751 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114041Expressed sequence AU022751.
Cep164 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114053Centrosomal protein of 164 kDa; Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface [...]
Plekhg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114056Pleckstrin homology domain-containing, family G (with RhoGef domain) member 1.
Qser1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114062Glutamine and serine-rich 1.
Zan protein networkhttps://string-db.org/network/10090.ENSMUSP00000114068Zonadhesin; Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.
Fkbp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114069Peptidyl-prolyl cis-trans isomerase FKBP8; Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitoc [...]
Sgk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114074Serine/threonine-protein kinase Sgk1; Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cellular enzymes, transcription [...]
Igf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114076Insulin-like growth factor II; The insulin-like growth factors possess growth-promoting activity (Probable). Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental de [...]
Phtf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114087Putative homeodomain transcription factor 2; May play a role in transcription regulation.
Ccdc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114088Coiled-coil domain-containing protein 9.
Tex35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114092Testis-expressed protein 35.
Gask1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000114093Golgi-associated kinase 1B; Belongs to the GASK family.
Rab27b protein networkhttps://string-db.org/network/10090.ENSMUSP00000114094Ras-related protein Rab-27B; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis [...]
Crybg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114099Crystallin beta-gamma domain-containing 2; Belongs to the beta/gamma-crystallin family.
Olfr20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114110Olfactory receptor.
Mrpl24 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011411139S ribosomal protein L24, mitochondrial; Belongs to the universal ribosomal protein uL24 family.
Fzd10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114114Frizzled-10; Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled prote [...]
Zar1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000114116Zygote arrest 1-like.
Erbb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114123Receptor tyrosine-protein kinase erbB-4; Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the hear [...]
Snrk protein networkhttps://string-db.org/network/10090.ENSMUSP00000114132SNF-related serine/threonine-protein kinase; May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis (By similarity).
Prdx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114159Peroxiredoxin-1; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection agains [...]
Paqr6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114166Membrane progestin receptor delta; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(s) mediated pathway. Involved in neurosteroid inhibition of apoptosis [...]
Pou6f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114173POU domain, class 6, transcription factor 2; Probable transcription factor likely to be involved in early steps in the differentiation of amacrine and ganglion cells. Recognizes and binds to the [...]
Mgat4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000114175Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form; Glycosyltransferase that participates in the transfer of N- acetylglucosamine (GlcNAc) to the core mannose r [...]
Ubc protein networkhttps://string-db.org/network/10090.ENSMUSP00000114180Ubiquitin-related 1; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond eit [...]
Lgals8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114200Galectin-8; Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. De [...]
Tlcd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114202TLC domain-containing protein 1; Regulates the composition and fluidity of the plasma membrane (By similarity). Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 [...]
Fzr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114203Fizzy-related protein homolog; Substrate-specific adapter for the anaphase promoting complex/cyclosome (APC/C) E3 ubiquitin-protein ligase complex. Associates with the APC/C in late mitosis, in r [...]
Dcaf11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114211DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Tbpl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114223TATA box-binding protein-like protein 1; Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter [...]
Etnk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114272Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity.
Enpp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114273Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, secreted form; Nucleotide pyrophosphatase that generates diphosphate (PPi) and functions in bone mineralization and soft tissue c [...]
Zfp97 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114301Zinc finger protein 97.
Aldh1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114304Cytosolic 10-formyltetrahydrofolate dehydrogenase; In the N-terminal section; belongs to the GART family.
Rit2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114323GTP-binding protein Rit2; Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator. Belongs to the small GTPase superfamily. Ras family.
Cerkl protein networkhttps://string-db.org/network/10090.ENSMUSP00000114325Ceramide kinase-like isoform 1.
Tcp10a protein networkhttps://string-db.org/network/10090.ENSMUSP00000114351T-complex protein 10a.
Ccdc42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114381Coiled-coil domain-containing protein 42; Required for sperm development. Belongs to the CFAP73 family.
Fam83e protein networkhttps://string-db.org/network/10090.ENSMUSP00000114397Protein FAM83E; May play a role in MAPK signaling. Belongs to the FAM83 family.
Mrps25 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011440228S ribosomal protein S25, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS25 family.
Ikzf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114404Zinc finger protein Eos; DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros- binding sequence. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via re [...]
Pa2g4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114434Proliferation-associated protein 2G4; May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) an [...]
Arl4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000114458ADP-ribosylation factor-like protein 4A; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleot [...]
Osgin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114467Oxidative stress-induced growth inhibitor 1; Regulates the differentiation and proliferation through the regulation of cell death.
Kctd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114489BTB/POZ domain-containing protein KCTD9; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of target proteins, leading to [...]
Akap5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114495A-kinase anchor protein 5; May anchor the PKA kinase to cytoskeletal and/or organelle- associated proteins, targeting the signal carried by cAMP to specific intracellular effectors.
Ttc38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114504Tetratricopeptide repeat protein 38.
Ahnak2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114522AHNAK nucleoprotein 2.
Trdmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114572tRNA (cytosine(38)-C(5))-methyltransferase; Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).
Mrvi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114578Protein MRVI1; Plays a role as NO/PRKG1-dependent regulator of IP3-induced calcium release; its phosphorylation by PRKG1 inhibits bradykinin and IP3-induced calcium release from intracellular sto [...]
Ugt2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114583UDP-glucuronosyltransferase 2A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water so [...]
Pus7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114588Pseudouridylate synthase 7 homolog; Pseudouridylate synthase that catalyzes pseudouridylation of RNAs. Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylat [...]
Lce6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000114595Late cornified envelope 6A.
Tex30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114624Testis-expressed protein 30.
Ino80c protein networkhttps://string-db.org/network/10090.ENSMUSP00000114643INO80 complex subunit C; Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
Stox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114652Storkhead-box protein 1; Involved in regulating the levels of reactive oxidative species and reactive nitrogen species and in mitochondrial homeostasis in the placenta (By similarity). Required f [...]
Gm14410 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114668Predicted gene 14410.
Mettl16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114682RNA N6-adenosine-methyltransferase METTL16; RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl- L-methionine homeos [...]
Mamstr protein networkhttps://string-db.org/network/10090.ENSMUSP00000114686MEF2-activating motif and SAP domain-containing transcriptional regulator; Transcriptional coactivator. Stimulates the transcriptional activity of MEF2C. Stimulates MYOD1 activity in part via MEF [...]
Fktn protein networkhttps://string-db.org/network/10090.ENSMUSP00000114699Fukutin; Catalyzes the transfer of CDP-ribitol to the distal N- acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N- acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosp [...]
Dbi protein networkhttps://string-db.org/network/10090.ENSMUSP00000114705Acyl-CoA-binding protein; Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepa [...]
Urb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114717Nucleolar pre-ribosomal-associated protein 1.
Tcte2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114746T-complex-associated testis-expressed 2.
Ube2v1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114764Ubiquitin-conjugating enzyme E2 variant 1.
Taf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114765Transcription initiation factor TFIID subunit 1; Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which [...]
Tnrc18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114769Trinucleotide repeat-containing gene 18 protein.
Ccdc13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114787Coiled-coil domain-containing protein 13; Required for primary cilia formation and promotes the localization of the ciliopathy protein BBS4 to both centriolar satellites and cilia.
Arpc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114839Actin-related protein 2/3 complex subunit 4; Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting fact [...]
Syvn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114843E3 ubiquitin-protein ligase synoviolin; Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substr [...]
Sap30bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000114844SAP30-binding protein; Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival (By similarity). May be involved in the regulation of beta-2-microglobulin g [...]
Plcxd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114852PI-PLC X domain-containing protein 2.
Bola2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114873BolA-like protein 2; Acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins. Acts together with the monothi [...]
Mus81 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114895Crossover junction endonuclease MUS81; Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch [...]
Aire protein networkhttps://string-db.org/network/10090.ENSMUSP00000114904Autoimmune regulator; Transcription factor playing an essential role to promote self-tolerance in the thymus by regulating the expression of a wide array of self-antigens that have the commonalit [...]
Coa7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114906Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV.
Efcab6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114909EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogati [...]
Lrrc14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114921Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB.
Grm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114927Metabotropic glutamate receptor 5; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G protein [...]
Dynlrb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114928Dynein light chain roadblock-type 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and [...]
Fsd1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000114931FSD1-like protein.
Gm43191 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114952Predicted gene 43191.
Ndufb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114963NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not [...]
Plrg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000114968Pleiotropic regulator 1; Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for act [...]
Spopl protein networkhttps://string-db.org/network/10090.ENSMUSP00000114974Speckle-type POZ protein-like; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of [...]
Tbl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115011Transducin beta-like protein 2.
Prl2c5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115024Prolactin-2C5.
Sumo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115044Small ubiquitin-related modifier 2; Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to it [...]
Dsp protein networkhttps://string-db.org/network/10090.ENSMUSP00000115062Desmoplakin; Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anch [...]
Svil protein networkhttps://string-db.org/network/10090.ENSMUSP00000115078Supervillin; [Isoform 1]: Forms a high-affinity link between the actin cytoskeleton and the membrane. Is among the first costameric proteins to assemble during myogenesis and it contributes to my [...]
Gatc protein networkhttps://string-db.org/network/10090.ENSMUSP00000115090Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. [...]
Ifi214 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115105Interferon-activated gene 214.
Rtl10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115114Retrotransposon Gag-like 10.
Sycp2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000115127Synaptonemal complex protein 2-like; Oocyte-specific protein that localizes to centromeres at the dictyate stage and regulates the survival of primordial oocytes. Belongs to the SYCP2 family.
Frmd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115136FERM domain-containing protein 5; May be involved in regulation of cell migration. May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail intera [...]
Apoc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115173Apolipoprotein C-II; Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lip [...]
Oip5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115219Protein Mis18-beta; Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
Phactr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115228Phosphatase and actin regulator 1; Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, ce [...]
Sox3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115237Transcription factor SOX-3; Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferenti [...]
Drp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115246Dystrophin-related protein 2; Required for normal myelination and for normal organization of the cytoplasm and the formation of Cajal bands in myelinating Schwann cells. Required for normal PRX l [...]
Adad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115260Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA.
Tmem216 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115319Transmembrane protein 216; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition.
Txnl4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000115320Thioredoxin-like protein 4A; Plays role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the preca [...]
Fzd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115325Frizzled-3; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of [...]
Uxt protein networkhttps://string-db.org/network/10090.ENSMUSP00000115342Protein UXT; Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor AR-mediated transcription. Together with URI1, associates with chro [...]
Trp53rkb protein networkhttps://string-db.org/network/10090.ENSMUSP00000115353EKC/KEOPS complex subunit Tp53rk; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codon [...]
Aldh3b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115356Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family.
Zfp128 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115378Zinc finger protein 8; Transcriptional repressor. May modulate BMP and TGF-beta signal transduction, through its interaction with SMAD proteins.
Gm28305 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115381Predicted gene 28305.
Gm13941 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115383Predicted gene 13941.
Adcy3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115406Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its func [...]
Gm48551 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115416Predicted gene, 48551.
Cox7c protein networkhttps://string-db.org/network/10090.ENSMUSP00000115419Cytochrome c oxidase subunit 7C, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The re [...]
Gm28042 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115498Phospholipase A2.
Pld6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115503Mitochondrial cardiolipin hydrolase; Endonuclease that plays a critical role in PIWI-interacting RNA (piRNA) biogenesis during spermatogenesis. piRNAs provide essential protection against the act [...]
Mrpl15 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011551239S ribosomal protein L15, mitochondrial.
Gprin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115539G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth.
Rgs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115558Regulator of G-protein signaling 2; Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby dr [...]
Gm4969 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115575Predicted gene 4969.
Rreb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115599Ras-responsive element-binding protein 1; Transcription factor that binds specifically to the RAS- responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differenti [...]
Msto1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115645Protein misato homolog 1; Involved in the regulation of mitochondrial distribution and morphology. Required for mitochondrial fusion and mitochondrial network formation.
Trim45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115669Tripartite motif-containing protein 45; May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway.
Aamdc protein networkhttps://string-db.org/network/10090.ENSMUSP00000115672Mth938 domain-containing protein; May play a role in preadipocyte differentiation and adipogenesis; Belongs to the AAMDC family.
Cep128 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115679Centrosomal protein of 128 kDa.
Srrm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115695Serine/arginine repetitive matrix protein 3; May play a role in regulating breast cancer cell invasiveness. May be involved in RYBP-mediated breast cancer progression; Belongs to the CWC21 family [...]
Ptgr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115704Prostaglandin reductase 2; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-P [...]
Als2cl protein networkhttps://string-db.org/network/10090.ENSMUSP00000115718ALS2 C-terminal-like protein; Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics (By similarity).
Rpl13a protein networkhttps://string-db.org/network/10090.ENSMUSP0000011572260S ribosomal protein L13a; Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions (By similarity). Component of the GAIT (gamma interfero [...]
Pitpna protein networkhttps://string-db.org/network/10090.ENSMUSP00000115723Phosphatidylinositol transfer protein alpha isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.
AU022252 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115729Uncharacterized protein C1orf50 homolog.
Ube2e2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115738Ubiquitin-conjugating enzyme E2 E2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'- [...]
Dna2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115750DNA replication ATP-dependent helicase/nuclease DNA2; Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion. Involved in Okazaki fragments processing by cleaving long [...]
Slc35e1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115754Solute carrier family 35 member E1; Putative transporter; Belongs to the TPT transporter family. SLC35E subfamily.
St3gal6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115756Type 2 lactosamine alpha-2,3-sialyltransferase; Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Ga [...]
Cnih4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115772Protein cornichon homolog 4; Involved in G protein-coupled receptors (GPCRs) trafficking from the endoplasmic reticulum to the cell surface; it promotes the exit of GPCRs from the early secretory [...]
Acte1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115809Actin, epsilon 1; Belongs to the actin family.
Asb8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115813Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquiti [...]
Fam129a protein networkhttps://string-db.org/network/10090.ENSMUSP00000115822Protein Niban 1; Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress re [...]
Knstrn protein networkhttps://string-db.org/network/10090.ENSMUSP00000115860Small kinetochore-associated protein; Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase tra [...]
Fam241b protein networkhttps://string-db.org/network/10090.ENSMUSP00000115865Protein FAM241B; May play a role in lysosome homeostasis. Belongs to the FAM241 family.
Prpf40b protein networkhttps://string-db.org/network/10090.ENSMUSP00000115869Pre-mRNA-processing factor 40 homolog B; May be involved in pre-mRNA splicing; Belongs to the PRPF40 family.
Slain2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115871SLAIN motif-containing protein 2; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation [...]
Rufy4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115873RUN and FYVE domain-containing protein 4; Positively regulates macroautophagy in primary dendritic cells. Increases autophagic flux, probably by stimulating both autophagosome formation and facil [...]
Psmg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115881Proteasome assembly chaperone 4; Chaperone protein which promotes assembly of the 20S proteasome; Belongs to the PSMG4 family.
Med28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115882Mediator of RNA polymerase II transcription subunit 28; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Vegfa protein networkhttps://string-db.org/network/10090.ENSMUSP00000115883Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits a [...]
Dhodh protein networkhttps://string-db.org/network/10090.ENSMUSP00000115934Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
Rtl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000115957Retrotransposon-like protein 1; Plays an essential role in capillaries endothelial cells for the maintenance of feto-maternal interface and for development of the placenta.
Satb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116006DNA-binding protein SATB1; Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organization [...]
Myo5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000116028Unconventional myosin-Va; Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates th [...]
Tril protein networkhttps://string-db.org/network/10090.ENSMUSP00000116056TLR4 interactor with leucine rich repeats; Component of the TLR4 signaling complex. Mediates the innate immune response to bacterial lipopolysaccharide (LPS) leading to cytokine secretion (By sim [...]
Rfx6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116057DNA-binding protein RFX6; Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 isl [...]
Mrpl48 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011609039S ribosomal protein L48, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL48 family.
Dhdds protein networkhttps://string-db.org/network/10090.ENSMUSP00000116098Dehydrodolichyl diphosphate synthase complex subunit Dhdds; With NUS1, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) b [...]
Nol12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116103Nucleolar protein 12; May bind to 28S rRNA. In vitro binds single-stranded nucleic acids.
Tcp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116108T-complex protein 1 subunit alpha; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC comple [...]
Abhd13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116130Protein ABHD13.
Sertad4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116176SERTA domain-containing protein 4.
Stxbp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116191Syntaxin-binding protein 4; Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to [...]
Pdlim2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116200PDZ and LIM domain protein 2; Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression en [...]
Stag1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116205Cohesin subunit SA-1; Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring [...]
Adgrb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116231Adhesion G protein-coupled receptor B3; Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity. [...]
Tmem229a protein networkhttps://string-db.org/network/10090.ENSMUSP00000116234Transmembrane protein 229A.
Pkn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116235Serine/threonine-protein kinase N1; PKC-related serine/threonine-protein kinase involved in various processes such as regulation of the intermediate filaments of the actin cytoskeleton, cell migr [...]
Gm11444 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116236Predicted gene 11444.
Bfsp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116249Phakinin; Required for the correct formation and organization of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
Grwd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116252Glutamate-rich WD repeat-containing protein 1; Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting [...]
Srpk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116259SRSF protein kinase 1; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, know [...]
Lcp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116271Plastin-2; Actin-binding protein. Plays a role in the activation of T- cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and [...]
2310061I04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000116278RIKEN cDNA 2310061I04 gene.
Mfsd4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000116282Major facilitator superfamily domain-containing protein 4A; Belongs to the major facilitator superfamily.
Entpd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116285Ectonucleoside triphosphate diphosphohydrolase 1; In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the preven [...]
Setd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116313Histone-lysine N-methyltransferase SETD2; Histone methyltransferase that specifically trimethylates 'Lys-36' of histone H3 (H3K36me3) using dimethylated 'Lys-36' (H3K36me2) as substrate. It is ca [...]
Tmub2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116327Transmembrane and ubiquitin-like domain-containing protein 2.
Cd209f protein networkhttps://string-db.org/network/10090.ENSMUSP00000116355CD209f antigen.
Gm20878 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116356Predicted gene, 20878.
Gm37240 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116393Predicted gene, 37240.
Cd209g protein networkhttps://string-db.org/network/10090.ENSMUSP00000116397CD209g antigen.
Samt1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000116409Spermatogenesis-associated multipass transmembrane protein 1b.
Rapgef3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116426Rap guanine nucleotide exchange factor 3; Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RA [...]
Syna protein networkhttps://string-db.org/network/10090.ENSMUSP00000116437Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties. Together with Synb, participates in trophoblast fusion and the formation of a sy [...]
Eef1b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116492Elongation factor 1-beta; EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
Mapkap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116494Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast [...]
Rdh16f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116574RDH16 family member 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Elp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116575Elongator complex protein 4; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in trans [...]
Ccdc167 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116591Coiled-coil domain-containing protein 167.
Wdr54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116608WD repeat-containing protein 54; When cross-linked to form dimers and trimers, it has a regulatory effect on ERK signaling pathway activity in response to EGF stimulation. Colocalizes with the EG [...]
Gm14418 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116617Predicted gene 14322.
Adhfe1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116627Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of [...]
Cd101 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116643Immunoglobulin superfamily member 2; Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine k [...]
Slc16a11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116648Monocarboxylate transporter 11; Proton-linked monocarboxylate transporter. It catalyzes the transport of pyruvate across the plasma membrane. Probably involved in hepatic lipid metabolism: overex [...]
2610001J05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000116702RIKEN cDNA 2610001J05 gene.
Tnfrsf23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116742Tumor necrosis factor receptor superfamily member 23; Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells a [...]
Mrpl58 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116746Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that [...]
Slc4a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116747Anion exchange protein 3; Plasma membrane anion exchange protein; Belongs to the anion exchanger (TC 2.A.31) family.
Sypl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116756Synaptophysin-like protein 2; Involved in communication between the T-tubular and junctional sarcoplasmic reticulum (SR) membranes.
Tnfrsf14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116757Tumor necrosis factor receptor superfamily member 14; Receptor for four distinct ligands: The TNF superfamily members TNFSF14/LIGHT and homotrimeric LTA/lymphotoxin-alpha and the immunoglobulin s [...]
Fam131b protein networkhttps://string-db.org/network/10090.ENSMUSP00000116779Protein FAM131B.
Nhej1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116797Non-homologous end-joining factor 1; DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a brid [...]
Dnajc21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116865DnaJ homolog subfamily C member 21; May act as a co-chaperone for HSP70. May play a role in ribosomal RNA (rRNA) biogenesis, possibly in the maturation of the 60S subunit. Binds the precursor 45S [...]
Malrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116869MAM and LDL-receptor class A domain-containing protein 1; Enhances production and/or transport of FGF15 and thus has a role in regulation of bile acid synthesis.
Pcdh19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116886Protocadherin-19; Potential calcium-dependent cell-adhesion protein.
Ganc protein networkhttps://string-db.org/network/10090.ENSMUSP00000116898Neutral alpha-glucosidase C; Has alpha-glucosidase activity; Belongs to the glycosyl hydrolase 31 family.
A630010A05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000116904RIKEN cDNA A630010A05 gene.
Pigyl protein networkhttps://string-db.org/network/10090.ENSMUSP00000116929Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y; Component of the GPI-GlcNAc transferase (GPI-GnT) complex in the endoplasmic reticulum, a complex that catalyzes transfer of GlcNAc [...]
Trpc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000116934Transient receptor potential cation channel, subfamily C, member 2.
Pter protein networkhttps://string-db.org/network/10090.ENSMUSP00000117009Phosphotriesterase-related protein.
Alas1 protein networkhttps://string-db.org/network/10090.ENSMUSP000001170145-aminolevulinate synthase, nonspecific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Igsf9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000117017Protein turtle homolog B; Transmembrane protein which is abundantly expressed in interneurons, where it may regulate inhibitory synapse development (By similarity). May mediate homophilic cell ad [...]
Nme1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117022Nucleoside diphosphate kinase A; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism [...]
Agpat5 protein networkhttps://string-db.org/network/10090.ENSMUSP000001170251-acyl-sn-glycerol-3-phosphate acyltransferase epsilon; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by [...]
Pfkp protein networkhttps://string-db.org/network/10090.ENSMUSP00000117030ATP-dependent 6-phosphofructokinase, platelet type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
H60b protein networkhttps://string-db.org/network/10090.ENSMUSP00000117032Histocompatibility antigen 60b; Ligand for the KLRK1 immunosurveillance receptor. Binding to KLRK1 stimulates cell lysis in vitro.
Ppargc1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000117040Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PP [...]
Srsf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117045Serine/arginine-rich splicing factor 3; Splicing factor that specifically promotes exon-inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and b [...]
Derl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117052Derlin-2; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel [...]
Dcaf10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117082DDB1- and CUL4-associated factor 10; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat DCAF10 family.
Ism2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117108Isthmin 2.
Itgb3bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000117153Centromere protein R; Transcription coregulator that can have both coactivator and corepressor functions. Involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormo [...]
Sf3a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117160Splicing factor 3A subunit 2; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of [...]
Dact1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117169Dapper homolog 1; Involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways throu [...]
Gm5724 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117177Solute carrier organic anion transporter family member.
Gm20521 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117229Predicted gene 20521.
Hars2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117231Histidine--tRNA ligase, mitochondrial; Mitochondrial aminoacyl-tRNA synthetase that catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an am [...]
Fen1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117246Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhan [...]
Gm49369 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117247Predicted gene, 49369; Belongs to the peptidase A1 family.
Lrrtm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117263Leucine-rich repeat transmembrane neuronal protein 4; May play a role in the development and maintenance of the vertebrate nervous system. Exhibits strong synaptogenic activity, restricted to exc [...]
Rhox13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117271Homeobox protein Rhox13; Probable transcription factor.
Sft2d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117294SFT2 domain containing 1.
Haus2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117299HAUS augmin-like complex subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex; Belongs to [...]
Cnot7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117304CCR4-NOT transcription complex subunit 7; Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalyti [...]
Cdh8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117326Cadherin-8; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the s [...]
Sgms1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117336Phosphatidylcholine:ceramide cholinephosphotransferase 1; Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, [...]
Ap3m1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117346AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral struct [...]
Erp29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117347Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possib [...]
Asxl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117384Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive s [...]
Zdhhc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117392Palmitoyltransferase ZDHHC3; Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/ [...]
Smyd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117410Histone-lysine N-methyltransferase SMYD3; Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Also methylates 'Lys [...]
Tbc1d14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117414TBC1 domain family member 14; Plays a role in the regulation of starvation-induced autophagosome formation. Together with the TRAPPIII complex, regulates a constitutive trafficking step from peri [...]
A830018L16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000117421Uncharacterized protein C8orf34 homolog.
Rpl12 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011746160S ribosomal protein L12; Binds directly to 26S ribosomal RNA.
Pakap-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117466Paralemmin A kinase anchor protein.
Mef2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000117496Myocyte-specific enhancer factor 2A; Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the act [...]
Gpd1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000117509Glycerol-3-phosphate dehydrogenase 1-like protein; Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3- phosphate activat [...]
Lsm11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117531U7 snRNA-associated Sm-like protein LSm11; Component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA [...]
Csrnp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117533Cysteine/serine-rich nuclear protein 3; Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. Plays a role in apoptosis. Belongs to the AXUD1 family.
Engase protein networkhttps://string-db.org/network/10090.ENSMUSP00000117538Cytosolic endo-beta-N-acetylglucosaminidase; Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N'-diacetylchitobiose core. Involved in t [...]
Myh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117569Myosin-1; Muscle contraction.
Micos10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117583MICOS complex subunit Mic10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner mem [...]
Tpr protein networkhttps://string-db.org/network/10090.ENSMUSP00000117616Nucleoprotein TPR; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the [...]
Ccbe1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117636Collagen and calcium-binding EGF domain-containing protein 1; Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis; Belongs to the CCBE1 fami [...]
Gm20547 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117677Predicted gene 20547; Belongs to the peptidase S1 family.
Fbxo30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117687F-box only protein 30; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Required for muscle atrophy following denervation.
Tpd52l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117690Tumor protein D54.
Wdr17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117710WD repeat domain 17.
Mest protein networkhttps://string-db.org/network/10090.ENSMUSP00000117713Mesoderm-specific transcript protein; Belongs to the AB hydrolase superfamily.
Zpr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117725Zinc finger protein ZPR1; Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus. Plays a role for the localization and accumulation of the [...]
Nsd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117778Histone-lysine N-methyltransferase NSD3; Histone methyltransferase. Preferentially dimethylates 'Lys- 4' and 'Lys-27' of histone H3 forming H3K2me2 and H3K27me2. H3 'Lys-4' methylation represents [...]
Slmap protein networkhttps://string-db.org/network/10090.ENSMUSP00000117816Sarcolemmal membrane-associated protein; May play a role during myoblast fusion.
Rpl29 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011783460S ribosomal protein L29; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL29 family.
Wt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117891Wilms tumor protein homolog; Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'- GCG(T/G)GGGCG-3' (By similar [...]
Odam protein networkhttps://string-db.org/network/10090.ENSMUSP00000117898Odontogenic ameloblast-associated protein; Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the [...]
Ppm1m protein networkhttps://string-db.org/network/10090.ENSMUSP00000117908Protein phosphatase 1M; Belongs to the PP2C family.
Pax9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117928Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as dista [...]
Snrpa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117947U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA.
Podxl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117954Podocalyxin-like protein 2; Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with [...]
Rfx5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000117963DNA-binding protein Rfx5; Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters. Bel [...]
Mrpl17 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011797139S ribosomal protein L17, mitochondrial.
Ppia protein networkhttps://string-db.org/network/10090.ENSMUSP00000117987Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein [...]
Ift20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118015Intraflagellar transport protein 20 homolog; Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins [...]
Fam47e protein networkhttps://string-db.org/network/10090.ENSMUSP00000118033Family with sequence similarity 47, member E.
Myo7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000118046Unconventional myosin-VIIb; Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relati [...]
Spx protein networkhttps://string-db.org/network/10090.ENSMUSP00000118062Spexin-1; Plays a role as a central modulator of cardiovascular and renal function and nociception. Plays also a role in energy metabolism and storage. Inhibits adrenocortical cell proliferation [...]
Rasd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118070GTP-binding protein Rhes; GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, G [...]
Sntg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118101Gamma-1-syntrophin; Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystro [...]
Taf10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118105Transcription initiation factor TFIID subunit 10; TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is a [...]
Sbf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118107Myotubularin-related protein 5; Acts as an adapter for the phosphatase MTMR2 to regulate MTMR2 catalytic activity and subcellular location. May function as a guanine nucleotide exchange factor (G [...]
Rell1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118125RELT-like protein 1; Induces activation of MAPK14/p38 cascade, when overexpressed. Induces apoptosis, when overexpressed; Belongs to the RELT family.
Lgals3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118169Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for ter [...]
Copa protein networkhttps://string-db.org/network/10090.ENSMUSP00000118179Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynt [...]
Mfsd14b protein networkhttps://string-db.org/network/10090.ENSMUSP00000118180Hippocampus abundant transcript-like protein 1.
Slx1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000118182Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombinati [...]
Ndst3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118207Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosam [...]
Sri protein networkhttps://string-db.org/network/10090.ENSMUSP00000118221Sorcin; Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 [...]
Apol6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118257Apolipoprotein L 6.
Gm44805 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118305Predicted gene 44805.
Slf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118312SMC5-SMC6 complex localization factor protein 1; Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance. Th [...]
Afdn protein networkhttps://string-db.org/network/10090.ENSMUSP00000118318Afadin; Belongs to an adhesion system, probably together with the E- cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens [...]
St18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118322Suppression of tumorigenicity 18 protein; Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleot [...]
Ube2j1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118333Ubiquitin-conjugating enzyme E2 J1; Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic re [...]
Bola3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118348BolA-like protein 3; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins. Probably acts together w [...]
Zfp407 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118361Zinc finger protein 407.
Selenoi protein networkhttps://string-db.org/network/10090.ENSMUSP00000118368Ethanolaminephosphotransferase 1; Catalyzes phosphatidylethanolamine biosynthesis from CDP- ethanolamine. It thereby plays a central role in the formation and maintenance of vesicular membranes. [...]
Lipo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118385Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
Zfp568 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118387Zinc finger protein 568; Has transcriptional repression activity, partially through the recruitment of the corepressor TRIM28 but has also repression activity independently of this interaction. E [...]
Laptm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118415Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells; Belongs to the LAPTM4/LAPTM5 transporter family.
Gm20431 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118416Predicted gene 20431.
Adgrl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118452Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive ex [...]
Pla2g4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000118458Cytosolic phospholipase A2 beta; Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position with a preference for arachidonoyl phospholipids. Has a m [...]
Rnf44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118474RING finger protein 44.
Ufm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118478Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine- linked polymer. The so-called ufmylation [...]
Abi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118491Abl interactor 1; May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. In vitro, at least isoform 2 and isoform 4 su [...]
Zscan4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000118506Zinc finger and SCAN domain containing protein 4C; Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomi [...]
Ldb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118546LIM domain-binding protein 1; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by de [...]
Gm20388 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118564Predicted gene 20388.
Mtch2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118566Mitochondrial carrier homolog 2; The substrate transported is not yet known. Induces mitochondrial depolarization (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family.
Cebpg protein networkhttps://string-db.org/network/10090.ENSMUSP00000118588CCAAT/enhancer-binding protein gamma; Transcription factor that binds to the promoter and the enhancer regions of target genes. Binds to the promoter and the enhancer of the immunoglobulin heavy [...]
Cend1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118591Cell cycle exit and neuronal differentiation protein 1; Involved in neuronal differentiation. Belongs to the CEND1 family.
Lpin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118610Phosphatidate phosphatase LPIN2; Plays important roles in controlling the metabolism of fatty acids at different levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catal [...]
Tdp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118656Tyrosyl-DNA phosphodiesterase 1; DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phospha [...]
Gm14419 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118666Predicted gene 14419.
Eif4e1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000118697Eukaryotic translation initiation factor 4E type 1B; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates rib [...]
Tmsb15l protein networkhttps://string-db.org/network/10090.ENSMUSP00000118704Thymosin beta 15b-like.
March11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118729E3 ubiquitin-protein ligase MARCHF11; E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the fo [...]
Sfxn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118743Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity).
Ankfy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118751Rabankyrin-5; Proposed effector of Rab5. Binds to phosphatidylinositol 3- phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin [...]
Terf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118759Telomeric repeat-binding factor 2; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes [...]
Treml4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118772Trem-like transcript 4 protein; Positively regulates Toll-like receptor signaling via TLR7, TLR9 and TLR13 in neutrophils and splenic macrophages. Regulates TLR7 signaling by controlling ligand- [...]
Dpm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118776Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathwa [...]
Immp2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000118779Mitochondrial inner membrane protease subunit 2; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into th [...]
Rpl22 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011878760S ribosomal protein L22.
1700029H14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000118793RIKEN cDNA 1700029H14 gene.
Zfp563 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118809Zinc finger protein 563.
Repin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118890Replication initiator 1; Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5'- ATT-3' reiterated sequences downstream of the o [...]
Lipo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118907Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
Zfr protein networkhttps://string-db.org/network/10090.ENSMUSP00000118911Zinc finger RNA-binding protein; Involved in postimplantation and gastrulation stages of development. Binds to DNA and RNA. Involved in the nucleocytoplasmic shuttling of STAU2 (By similarity).
Ndufb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118918NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not [...]
Yjefn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118931YjeF N-terminal domain-containing protein 3; May play a role in spermiogenesis and oogenesis.
2700049A03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000118956Protein TALPID3; Required for ciliogenesis and sonic hedgehog/SHH signaling. Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes [...]
Amy2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118962Alpha-amylase.
Ankrd33b protein networkhttps://string-db.org/network/10090.ENSMUSP00000118984Ankyrin repeat domain-containing protein 33B.
Cbfa2t3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000118997Protein CBFA2T3; Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and hist [...]
Tnfaip8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119041Tumor necrosis factor alpha-induced protein 8; Acts as a negative mediator of apoptosis. Suppresses the TNF- mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspa [...]
D3Ertd751e protein networkhttps://string-db.org/network/10090.ENSMUSP00000119049UPF0462 protein C4orf33 homolog.
1700021F05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000119053Mitochondrial transcription rescue factor 1; Mitochondrial RNA-binding protein involved in mitochondrial transcription regulation. Functions as a protective factor to maintain proper mitochondria [...]
Ehmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119057Histone-lysine N-methyltransferase EHMT1; Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me repre [...]
Srsf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119065Serine/arginine-rich splicing factor 6; Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10 [...]
Pqlc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119083Solute carrier family 66 member 2.
Zfp963 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119087Zinc finger protein 963.
Snx12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119102Sorting nexin-12; May be involved in several stages of intracellular trafficking.
Zfp369 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119114Neurotrophin receptor-interacting factor 2; Transcription regulator which may participate in NGFR/p75(NTR)-mediated apoptosis. Probably acts as a transcription repressor: specifically binds to th [...]
Fbxl12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119124F-box/LRR-repeat protein 12; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the polyubiquitination and proteasomal degradation of [...]
Ginm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119129Glycoprotein integral membrane protein 1.
Cenpo protein networkhttps://string-db.org/network/10090.ENSMUSP00000119136Centromere protein O; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chr [...]
Saa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119150Serum amyloid A-1 protein; Major acute phase protein.
Bbx protein networkhttps://string-db.org/network/10090.ENSMUSP00000119238HMG box transcription factor BBX; Transcription factor that is necessary for cell cycle progression from G1 to S phase.
Atp2b4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119242Plasma membrane calcium-transporting ATPase 4; Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the ce [...]
Pde6h protein networkhttps://string-db.org/network/10090.ENSMUSP00000119246Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector mo [...]
Utp23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119261rRNA-processing protein UTP23 homolog; Involved in rRNA-processing and ribosome biogenesis. Belongs to the UTP23/FCF1 family. UTP23 subfamily.
Numb protein networkhttps://string-db.org/network/10090.ENSMUSP00000119303Protein numb homolog; Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowi [...]
Rxylt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119308Ribitol-5-phosphate xylosyltransferase 1; UDP-xylosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3- N-acetylglucosamine-bet [...]
Comtd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119330Catechol O-methyltransferase domain-containing protein 1; Putative O-methyltransferase.
Nlk protein networkhttps://string-db.org/network/10090.ENSMUSP00000119345Serine/threonine-protein kinase NLK; Serine/threonine-protein kinase that regulates a number of transcription factors with key roles in cell fate determination. Positive effector of the non-canon [...]
Actl6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000119356Actin-like protein 6B; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remode [...]
Becn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119369Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a ro [...]
Zbtb10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119386Zinc finger and BTB domain-containing 10.
Gm15130 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119418Predicted gene 15130.
Mpc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119443Mitochondrial pyruvate carrier 1; Mediates the uptake of pyruvate into mitochondria.
Slc26a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119447Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation.
Aim2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119465Interferon-inducible protein AIM2; Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon bi [...]
1190005I06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000119467Uncharacterized protein C16orf74 homolog.
Tmem56 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119468TLC domain-containing protein 4; Belongs to the TLCD4 family.
Kif26a protein networkhttps://string-db.org/network/10090.ENSMUSP00000119482Kinesin-like protein KIF26A; Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, po [...]
Inpp5e protein networkhttps://string-db.org/network/10090.ENSMUSP00000119485Phosphatidylinositol polyphosphate 5-phosphatase type IV; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIn [...]
Fam111a protein networkhttps://string-db.org/network/10090.ENSMUSP00000119518Protein FAM111A; Chromatin-associated protein required for PCNA loading on replication sites. Promotes S-phase entry and DNA synthesis (By similarity); Belongs to the FAM111 family.
Mrps24 protein networkhttps://string-db.org/network/10090.ENSMUSP0000011953528S ribosomal protein S24, mitochondrial; Belongs to the universal ribosomal protein uS3 family.
Gm14401 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119549Predicted gene 14401.
Spg7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119552Paraplegin; ATP-dependent zinc metalloprotease. Plays a role in the formation and regulation of the mitochondrial permeability transition pore (mPTP) and its proteolytic activity is dispensable f [...]
Il9r protein networkhttps://string-db.org/network/10090.ENSMUSP00000119557Interleukin-9 receptor; This is a receptor for interleukin-9; Belongs to the type I cytokine receptor family. Type 4 subfamily.
Phb protein networkhttps://string-db.org/network/10090.ENSMUSP00000119603Prohibitin; Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitoc [...]
Pank2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119606Pantothenate kinase 2 (Hallervorden-Spatz syndrome).
Gtf3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000119607Transcription factor IIIA; Involved in ribosomal large subunit biogenesis. Binds the approximately 50 base pairs internal control region (ICR) of 5S ribosomal RNA genes. It is required for their [...]
Samd13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119608Sterile alpha motif domain-containing protein 13.
Mmrn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119609Multimerin-1; Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may li [...]
Prcd protein networkhttps://string-db.org/network/10090.ENSMUSP00000119671Photoreceptor disk component PRCD; Involved in vision; Belongs to the PRCD family.
Plekhd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119711Pleckstrin homology domain-containing family D member 1; Belongs to the PLEKHD1 family.
Rps6kb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119715Ribosomal protein S6 kinase beta-1; Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth a [...]
Agbl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119721Cytosolic carboxypeptidase 4; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational [...]
Mtfr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119724Mitochondrial fission regulator 1; May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission. Belongs to the MTFR1 family.
Sox13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119729Transcription factor SOX-13; Binds to the sequence 5'-AACAAT-3'.
Mpnd protein networkhttps://string-db.org/network/10090.ENSMUSP00000119745MPN domain-containing protein; Probable protease (By similarity). Acts as a sensor of N(6)- methyladenosine methylation on DNA (m6A): recognizes and binds m6A DNA, leading to its degradation (By [...]
Zpld1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119774Zona pellucida-like domain-containing protein 1, secreted form; Glycoprotein which is a component of the gelatinous extracellular matrix in the cupulae of the vestibular organ.
Zfp866 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119781Zinc finger protein 866.
Stum protein networkhttps://string-db.org/network/10090.ENSMUSP00000119782Protein stum homolog; Belongs to the SPEC3 family. Stum subfamily.
Heg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119790Protein HEG homolog 1; Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May be acting by stabilizing endothelial cell junc [...]
Hikeshi protein networkhttps://string-db.org/network/10090.ENSMUSP00000119806Protein Hikeshi; Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin- dependent translocation of ATP-bound HSP70 proteins i [...]
Apod protein networkhttps://string-db.org/network/10090.ENSMUSP00000119827Apolipoprotein D; APOD occurs in the macromolecular complex with lecithin- transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts; [...]
Vta1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119829Vacuolar protein sorting-associated protein VTA1 homolog; Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invaginati [...]
Lsm6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119841U6 snRNA-associated Sm-like protein LSm6; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatal [...]
Gm45902 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119850Predicted gene 45902.
Tmem63c protein networkhttps://string-db.org/network/10090.ENSMUSP00000119872Calcium permeable stress-gated cation channel 1; Acts as an osmosensitive calcium-permeable cation channel. Required for the functional integrity of the kidney glomerular filtration barrier (By s [...]
Pms2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119875Mismatch repair endonuclease PMS2; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MLH1 to form MutL alpha. DNA repair is initiated by MutS alpha (MSH2-MS [...]
Gm29094 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119881Predicted gene 29094.
Cdk5rap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119891CDK5 regulatory subunit-associated protein 2; Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centr [...]
Trmt9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000119912Probable tRNA methyltransferase 9B; May modifie wobble uridines in specific arginine and glutamic acid tRNAs. Acts as a tumor suppressor by promoting the expression of LIN9 (By similarity); Belon [...]
Uxs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119939UDP-glucuronic acid decarboxylase 1; Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminogly [...]
Gatb protein networkhttps://string-db.org/network/10090.ENSMUSP00000119949Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. [...]
Rps15a protein networkhttps://string-db.org/network/10090.ENSMUSP0000011997540S ribosomal protein S15a; Structural component of the ribosome. Required for proper erythropoiesis; Belongs to the universal ribosomal protein uS8 family.
BC067074 protein networkhttps://string-db.org/network/10090.ENSMUSP00000119993cDNA sequence BC067074.
Dync2h1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120007Cytoplasmic dynein 2 heavy chain 1; May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis. According to it may play a role in transport between endoplasmi [...]
Nhp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120014H/ACA ribonucleoprotein complex subunit 2; Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes p [...]
Gpr137c protein networkhttps://string-db.org/network/10090.ENSMUSP00000120015G protein-coupled receptor 137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes.
Dcaf17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120016DDB1- and CUL4-associated factor 17; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
1500009C09Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000120070RIKEN cDNA 1500009C09 gene.
Sap18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120071Sin3-associated polypeptide 18.
Mrps14 protein networkhttps://string-db.org/network/10090.ENSMUSP0000012007528S ribosomal protein S14, mitochondrial; Belongs to the universal ribosomal protein uS14 family.
Cep350 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120085Centrosome-associated protein 350; Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to th [...]
Uba52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120096Ubiquitin A-52 residue ribosomal protein fusion product 1.
Pfdn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120106Prefoldin subunit 2; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which the [...]
Hnrnpm protein networkhttps://string-db.org/network/10090.ENSMUSP00000120115Heterogeneous nuclear ribonucleoprotein M; Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoemb [...]
AI661453 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120133Uncharacterized protein C6orf132 homolog.
Zscan4f protein networkhttps://string-db.org/network/10090.ENSMUSP00000120149Zinc finger and SCAN domain containing protein 4F; Transcription factor required to regulate early development. Binds telomeres and plays a key role in genomic stability by regulating telomere el [...]
Stat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120152Signal transducer and activator of transcription 3; Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors (By sim [...]
Ggct protein networkhttps://string-db.org/network/10090.ENSMUSP00000120154Gamma-glutamylcyclotransferase; Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c [...]
Wipf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120240WAS/WASL-interacting protein family member 3; May be a regulator of cytoskeletal organization (Potential). May have a role in spermatogenesis.
Khdc1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000120275KH homology domain-containing protein 1B; Belongs to the KHDC1 family.
Hoxa10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120276Homeobox protein Hox-A10; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posteri [...]
Txndc16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120287Thioredoxin domain-containing protein 16.
Fsip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120314Fibrous sheath-interacting protein 2; Plays a role in spermatogenesis.
Gpc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120362Secreted glypican-6; Cell surface proteoglycan that bears heparan sulfate. Putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. Enhanc [...]
Ndc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120365Nucleoporin NDC1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assem [...]
Arfip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120387Arfaptin-2; Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which [...]
Zfp988 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120413Zinc finger protein 988.
Ythdf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120414YTH domain-containing family protein 2; Specifically recognizes and binds N6-methyladenosine (m6A)- containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites [...]
Nos1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120421Nitric oxide synthase, brain; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many pro [...]
Ergic2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120456Endoplasmic reticulum-Golgi intermediate compartment protein 2; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the ERGIC family.
Ubl4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000120461Ubiquitin-like protein 4A; As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches- containing proteins in a soluble state and p [...]
Plgrkt protein networkhttps://string-db.org/network/10090.ENSMUSP00000120466Plasminogen receptor (KT); Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator- dependent cell surface plasminogen activ [...]
Gm42791 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120502Predicted gene 42791.
Msi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120516RNA-binding protein Musashi homolog 1; RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA co [...]
Rps27l protein networkhttps://string-db.org/network/10090.ENSMUSP0000012051840S ribosomal protein S27.
Irf9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120525Interferon regulatory factor 9; Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and [...]
Rps20 protein networkhttps://string-db.org/network/10090.ENSMUSP0000012052840S ribosomal protein S20.
Tcirg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120531V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for asse [...]
Gm12830 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120534Predicted gene 12830.
Eri2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120547ERI1 exoribonuclease 2.
Optc protein networkhttps://string-db.org/network/10090.ENSMUSP00000120568Opticin; Inhibits angiogenesis in the vitreous humor of the eye, and therefore represses neovascularization. Binds collagen fibrils (By similarity). May be involved in collagen fiber organization [...]
Crocc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120588Ciliary rootlet coiled-coil, rootletin family member 2.
Srsf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120595Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal componen [...]
BC048679 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120616cDNA sequence BC048679.
Ppat protein networkhttps://string-db.org/network/10090.ENSMUSP00000120632Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Gpatch8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120649G patch domain-containing protein 8.
Saal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120658Protein SAAL1; Plays a role in promoting the proliferation of synovial fibroblasts in response to proinflammatory stimuli. Belongs to the SAAL1 family.
Prkrip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120659PRKR-interacting protein 1; Required for pre-mRNA splicing as component of the spliceosome (By similarity). Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity.
Tpsab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120741Tryptase; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity (By [...]
Lyrm7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120778Complex III assembly factor LYRM7; Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subuni [...]
Lrrc31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120802Leucine-rich repeat-containing 31.
Pkd1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120803Polycystic kidney disease protein 1-like 1; Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Fo [...]
Zcchc17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120807Nucleolar protein of 40 kDa.
Slc38a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120810Probable sodium-coupled neutral amino acid transporter 6; Probable sodium-dependent amino acid/proton antiporter, could be a neuronal transporter for glutamate.
Ankrd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120816Ankyrin repeat domain-containing protein 9.
Strn protein networkhttps://string-db.org/network/10090.ENSMUSP00000120830Striatin; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family.
Fbxo7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120840F-box only protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradati [...]
Cd84 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120881SLAM family member 5; Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating t [...]
Tmed7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120904Transmembrane p24-trafficking protein 7.
Tbl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120911Transducin beta-like protein 3.
Zbtb8os protein networkhttps://string-db.org/network/10090.ENSMUSP00000120925Protein archease; Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB. Together with DDX1, acts by facilitating the guanylylation [...]
Sh3rf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120938E3 ubiquitin-protein ligase SH3RF3; Has E3 ubiquitin-protein ligase activity.
Cmc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120966COX assembly mitochondrial protein 2 homolog; May be involved in cytochrome c oxidase biogenesis. Belongs to the CMC family.
Ucp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000120967Mitochondrial uncoupling protein 2; UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP [...]
Hadha protein networkhttps://string-db.org/network/10090.ENSMUSP00000120976Trifunctional enzyme subunit alpha, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial [...]
Tdg protein networkhttps://string-db.org/network/10090.ENSMUSP00000121000G/T mismatch-specific thymine DNA glycosylase; DNA glycosylase that plays a key role in active DNA demethylation: specifically recognizes and binds 5-formylcytosine (5fC) and 5-carboxylcytosine ( [...]
Hnrnpdl protein networkhttps://string-db.org/network/10090.ENSMUSP00000121005Heterogeneous nuclear ribonucleoprotein D-like; Acts as a transcriptional regulator. Promotes transcription repression (By similarity). Promotes transcription activation in differentiated myotube [...]
Raph1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121023Ras association (RalGDS/AF-6) and pleckstrin homology domains 1.
Sik3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121032Serine/threonine-protein kinase SIK3; Positive regulator of mTOR signaling that functions by triggering the degradation of DEPTOR, an mTOR inhibitor (By similarity). Required for chondrocyte hype [...]
Dnal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121038Dynein light chain 1, axonemal; Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm [...]
Dda1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121042DET1- and DDB1-associated protein 1; May be involved in ubiquitination and subsequent proteasomal degradation of target proteins. Component of the DDD-E2 complexes which may provide a platform fo [...]
Pcp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121079Purkinje cell protein 2; May function as a cell-type specific modulator for G protein- mediated cell signaling.
Map2k2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121111Dual specificity mitogen-activated protein kinase kinase 2; Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activ [...]
Sptan1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121116Spectrin alpha chain, non-erythrocytic 1; Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent [...]
Tle2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121125Transducin-like enhancer protein 2; Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members [...]
Gnb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121127Guanine nucleotide-binding protein subunit beta-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta [...]
Faf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121182FAS-associated factor 2; Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. [...]
Zfp85 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121202Zinc finger protein 85, related sequence 1.
Ctsd protein networkhttps://string-db.org/network/10090.ENSMUSP00000121203Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the pep [...]
Rfx8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121212DNA-binding protein RFX8; May be a transcription factor; Belongs to the RFX family.
Crem protein networkhttps://string-db.org/network/10090.ENSMUSP00000121233cAMP-responsive element modulator; Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcription [...]
Cnot6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121239CCR4-NOT transcription complex subunit 6; Poly(A) nuclease with 3'-5' RNase activity. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linke [...]
Uggt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121249UDP-glucose glycoprotein glucosyltransferase 2.
Dnhd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121261Dynein heavy chain domain 1.
Tab2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121266TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiqui [...]
Zfp738 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121275Zinc finger protein 738.
Gabpb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121283GA-binding protein subunit beta-2; Transcription factor capable of interacting with purine rich repeats (GA repeats). Must associate with GABP-alpha to bind DNA.
E130114P18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000121284RIKEN cDNA E130114P18 gene.
Zfp758 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121288Zinc finger protein 758.
Zfp993 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121301Zinc finger protein 993.
Sf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121309Splicing factor 1; Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repr [...]
Cnnm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121317Metal transporter CNNM4; Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a ro [...]
Tmem262 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121339Transmembrane protein 262.
Taf13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121346Transcription initiation factor TFIID subunit 13; Component of the DNA-binding general RNA polymerase II transcription factor IID complex (TFIID). TFIID plays a critical role in the regulation of [...]
Ide protein networkhttps://string-db.org/network/10090.ENSMUSP00000121358Insulin-degrading enzyme; Plays a role in the cellular breakdown of insulin, APP peptides, IAPP peptides, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellu [...]
Epn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121390Epsin-3; Belongs to the epsin family.
Spryd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121493SPRY domain-containing 3.
Nkiras1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121496NF-kappa-B inhibitor-interacting Ras-like protein 1; Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (N [...]
Desi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121504Desumoylating isopeptidase 1; Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46. Collaborates [...]
Ndufv2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121557NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minima [...]
Dnmt3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000121562DNA (cytosine-5)-methyltransferase 3-like; Catalytically inactive regulatory factor of DNA methyltransferases that can either promote or inhibit DNA methylation depending on the context. Essentia [...]
Cnbd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121576Cyclic nucleotide-binding domain-containing 1.
Aftph protein networkhttps://string-db.org/network/10090.ENSMUSP00000121612Aftiphilin; May play a role in membrane trafficking.
Mipol1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121617Mirror-image polydactyly gene 1 protein homolog.
Smim20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121637Small integral membrane protein 20; [Small integral membrane protein 20]: Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) comp [...]
Ssxb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121642Synovial sarcoma, X member B6.
Naa30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121679N-alpha-acetyltransferase 30; Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Le [...]
Gm15448 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121707Predicted gene 15448.
Ces1h protein networkhttps://string-db.org/network/10090.ENSMUSP00000121729Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
Slc4a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121744Electrogenic sodium bicarbonate cotransporter 1; Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux a [...]
Zbtb38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121753CtBP-interacting BTB zinc finger protein.
Aknad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121755AKNA domain-containing 1.
Slc45a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121775Solute carrier family 45 member 4; Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family.
Inpp4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000121803Inositol polyphosphate-4-phosphatase type I A; Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate. Catalyzes also inositol 1,3,4-trisphosphate and inosi [...]
Maskbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121811Multiple ankyrin repeats single KH domain-binding protein 3.
Fam222b protein networkhttps://string-db.org/network/10090.ENSMUSP00000121832Protein FAM222B; Belongs to the FAM222 family.
Smchd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121835Structural maintenance of chromosomes flexible hinge domain-containing protein 1; Non-canonical member of the structural maintenance of chromosomes (SMC) protein family that plays a key role in e [...]
Spaca9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121846Sperm acrosome-associated protein 9.
Clec5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000121848C-type lectin domain family 5 member A; Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses.
Tmem141 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121862Transmembrane protein 141.
Skint6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121870Selection and upkeep of intraepithelial T-cells protein 6; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus.
Gm16286 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121883Predicted gene 16286.
Gm281 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121887Predicted gene 281.
Arhgap26-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121894Rho GTPase-activating protein 26.
Lrrc37a protein networkhttps://string-db.org/network/10090.ENSMUSP00000121903Leucine-rich repeat-containing 37A.
Pgs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121973CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the [...]
Vamp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000121977Vesicle-associated membrane protein 4; Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory [...]
Bcorl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122000BCL-6 corepressor-like protein 1; Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence specific DNA- binding proteins such as BCL6. [...]
Gm42669 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122032AP2-interacting clathrin-endocytosis protein; Involved in clathrin-mediated endocytosis at the synapse. Plays a role in neuronal development and in synaptic vesicle recycling in mature neurons, a [...]
Dnajb12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122056DnaJ homolog subfamily B member 12; Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded prot [...]
Bbs9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122058Protein PTHB1; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis [...]
Ly6h protein networkhttps://string-db.org/network/10090.ENSMUSP00000122061Lymphocyte antigen 6H; Believed to act as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4- containing nAChRs maximum response. In vitro inhibits [...]
Arfrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122066ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipid [...]
Ramp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122072Receptor activity-modifying protein 2; Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CAL [...]
Ptgir protein networkhttps://string-db.org/network/10090.ENSMUSP00000122080Prostacyclin receptor; Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase; Belongs to the G-protein [...]
Snapin protein networkhttps://string-db.org/network/10090.ENSMUSP00000122090SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melano [...]
Slc25a12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122103Calcium-binding mitochondrial carrier protein Aralar1; Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartat [...]
Slc35d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122124UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter; Transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N- acetylgalactosamine (UDP-GalNAc) from the cytoplasm into the endoplasmic retic [...]
Gm14226 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122157Envelope polyprotein.
Megf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122192Multiple epidermal growth factor-like domains protein 8; Acts as a negative regulator of hedgehog signaling.
Usp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122199Ubiquitin carboxyl-terminal hydrolase 3; Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subseque [...]
Gm12666 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122212Predicted gene 12666.
Prlr protein networkhttps://string-db.org/network/10090.ENSMUSP00000122219Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.
Flad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122252Molybdenum cofactor biosynthesis protein-like region; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme; In the C-terminal section; belon [...]
Abhd5 protein networkhttps://string-db.org/network/10090.ENSMUSP000001222741-acylglycerol-3-phosphate O-acyltransferase ABHD5; Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfert of an acyl group on a lysophosphatidic acid. Functions [...]
Prn protein networkhttps://string-db.org/network/10090.ENSMUSP00000122345Prion protein readthrough transcript.
Rabepk protein networkhttps://string-db.org/network/10090.ENSMUSP00000122360Rab9 effector protein with kelch motifs; Rab9 effector required for endosome to trans-Golgi network (TGN) transport.
Smim14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122363Small integral membrane protein 14.
Dad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122366Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3 [...]
Asb7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122395Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquiti [...]
Abcc12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122402Multidrug resistance-associated protein 9; Probable transporter; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Nfyb protein networkhttps://string-db.org/network/10090.ENSMUSP00000122403Nuclear transcription factor Y subunit beta; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promo [...]
Cdc23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122420Cell division cycle protein 23 homolog; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the [...]
Ifi203 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122424Interferon-activable protein 203.
Polr3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000122435DNA-directed RNA polymerase III subunit RPC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core com [...]
Ube2k protein networkhttps://string-db.org/network/10090.ENSMUSP00000122471Ubiquitin-conjugating enzyme E2 K; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubi [...]
Nfe2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122476Transcription factor NF-E2 45 kDa subunit; Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 [...]
Arhgap21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122497Rho GTPase-activating protein 21; Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also requ [...]
Sbk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122507Uncharacterized serine/threonine-protein kinase SBK3.
Sgsm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122543Small G protein signaling modulator 3; May play a cooperative role in NF2-mediated growth suppression of cells.
Dhrs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122552Short-chain dehydrogenase/reductase 3; Catalyzes the reduction of all-trans-retinal to all-trans- retinol in the presence of NADPH.
Hoxd11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122582Homeobox protein Hox-D11; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posteri [...]
Mri1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122623Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/de [...]
Vmn2r66 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122645Vomeronasal 2, receptor 66.
Tmprss11g protein networkhttps://string-db.org/network/10090.ENSMUSP00000122709Transmembrane protease serine 11G non-catalytic chain.
Tnni2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122733Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase act [...]
Cenpa protein networkhttps://string-db.org/network/10090.ENSMUSP00000122831Histone H3-like centromeric protein A; Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric ch [...]
Myo9a protein networkhttps://string-db.org/network/10090.ENSMUSP00000122852Unconventional myosin-IXa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating it's GTPase activity [...]
Fign protein networkhttps://string-db.org/network/10090.ENSMUSP00000122855Fidgetin; ATP-dependent microtubule severing protein. Severs microtubules along their length and depolymerizes their ends, primarily the minus-end, suppressing microtubule growth from and attachm [...]
Mfap5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122863Microfibrillar-associated protein 5; May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel int [...]
Mfsd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122881Major facilitator superfamily domain-containing protein 6; MHC class I receptor. Binds only to H-2 class I histocompatibility antigen, K-D alpha chain (H-2K(D)).
Ccser1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122894Serine-rich coiled-coil domain-containing protein 1.
Aanat protein networkhttps://string-db.org/network/10090.ENSMUSP00000122895Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in [...]
Dlgap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122896Disks large-associated protein 1; Part of the postsynaptic scaffold in neuronal cells; Belongs to the SAPAP family.
Ppp1r3f protein networkhttps://string-db.org/network/10090.ENSMUSP00000122903Protein phosphatase 1 regulatory subunit 3F; Glycogen-targeting subunit for protein phosphatase 1 (PP1).
Kcnq2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122915Potassium voltage-gated channel subfamily KQT member 2; Associates with KCNQ3 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a s [...]
Malsu1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122941Mitochondrial assembly of ribosomal large subunit protein 1; Required for normal mitochondrial ribosome function and mitochondrial translation. May play a role in ribosome biogenesis by preventin [...]
Arfip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000122964ADP-ribosylation factor-interacting protein 1.
Xaf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123011XIAP-associated factor 1; Seems to function as a negative regulator of members of the IAP (inhibitor of apoptosis protein) family. Inhibits anti-caspase activity of BIRC4. Induces cleavage and in [...]
Exoc3l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123025Exocyst complex component 3-like 2.
Dlgap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123078Disks large-associated protein 2; May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoske [...]
Myef2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123088Myelin expression factor 2; Transcriptional repressor of the myelin basic protein gene (MBP). Binds to the proximal MB1 element 5'-TTGTCC-3' of the MBP promoter. Its binding to MB1 and function a [...]
Dusp15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123090Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6 (By similarity).
Zfp960 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123102Zinc finger protein 960.
Rasal3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123141RAS protein activator like-3; Functions as a Ras GTPase-activating protein. Plays an important role in the expansion and functions of natural killer T (NKT) cells in the liver by negatively regul [...]
Naa38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123155N-alpha-acetyltransferase 38, NatC auxiliary subunit; Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues; Belon [...]
Ttc39d protein networkhttps://string-db.org/network/10090.ENSMUSP00000123158Tetratricopeptide repeat domain 39D.
Bicc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123201Protein bicaudal C homolog 1; Putative RNA-binding protein. May be involved in regulating gene expression during embryonic development; Belongs to the BicC family.
Grip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123234Glutamate receptor-interacting protein 1; May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners a [...]
C330021F23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000123235Ribosomal protein S23, retrogene 1.
Reps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123238RalBP1-associated Eps domain-containing protein 1; May coordinate the cellular actions of activated EGF receptors and Ral-GTPases.
Stxbp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123253Syntaxin-binding protein 5; Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release (By similarity). Inhibits membrane fusion between transport vesicles and the plasm [...]
Rasal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123266RasGAP-activating-like protein 1; Probable inhibitory regulator of the Ras-cyclic AMP pathway. Plays a role in dendrite formation by melanocytes.
Ankhd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123270Ankyrin repeat and KH domain-containing 1.
Mrps26 protein networkhttps://string-db.org/network/10090.ENSMUSP0000012332428S ribosomal protein S26, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS26 family.
Rab9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123325Ras-related protein Rab-9A; Involved in the transport of proteins between the endosomes and the trans-Golgi network (By similarity). Involved in the recruitment of SGSM2 to melanosomes and is req [...]
Hal protein networkhttps://string-db.org/network/10090.ENSMUSP00000123336Histidine ammonia-lyase; Belongs to the PAL/histidase family.
Morc2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000123354ATPase MORC2B; Required for chromosomal synapsis and meiotic recombination in males and females.
Dennd4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000123367DENN domain-containing protein 4C; Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound fo [...]
Ccdc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123374Coiled-coil domain-containing protein 6.
Vinac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123404Vinculin/alpha-catenin family member 1.
Rpl27a protein networkhttps://string-db.org/network/10090.ENSMUSP0000012341060S ribosomal protein L27a.
Myl12a protein networkhttps://string-db.org/network/10090.ENSMUSP00000123412Myosin, light chain 12A, regulatory, non-sarcomeric.
Lin54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123425Protein lin-54 homolog; Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds [...]
Ermap protein networkhttps://string-db.org/network/10090.ENSMUSP00000123426Erythroid membrane-associated protein; Possible role as a cell-adhesion or receptor molecule of erythroid cells; Belongs to the immunoglobulin superfamily. BTN/MOG family.
Fam129c protein networkhttps://string-db.org/network/10090.ENSMUSP00000123432Family with sequence similarity 129, member C.
Gm14597 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123472Predicted gene 14597.
Gm4846 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123476Dimethylaniline monooxygenase [N-oxide-forming].
Tmem44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123494Transmembrane protein 44.
Flt3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000123506Fms-related tyrosine kinase 3 ligand; Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleuk [...]
Tnni1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123509Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase act [...]
Tafa3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123514Chemokine-like protein TAFA-3; Plays a role in the regulation of microglia polarization. Belongs to the TAFA family.
Ablim2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123525Actin-binding LIM protein 2; May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity.
Adck2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123563Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosp [...]
Sort1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123564Sortilin; Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a p [...]
Brwd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123588Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape (By similarity).
Usp10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123590Ubiquitin carboxyl-terminal hydrolase 10; Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, BECN1, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 st [...]
Ywhaq protein networkhttps://string-db.org/network/10090.ENSMUSP0000012360514-3-3 protein theta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognit [...]
Cox6c protein networkhttps://string-db.org/network/10090.ENSMUSP00000123609Cytochrome c oxidase subunit 6C; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain [...]
Igfl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123628Insulin growth factor-like family member; Probable ligand of the IGFLR1 cell membrane receptor.
Olfr392 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123649Olfactory receptor.
Eapp protein networkhttps://string-db.org/network/10090.ENSMUSP00000123698E2F-associated phosphoprotein; May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry [...]
Hyou1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123700Hypoxia up-regulated protein 1; Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein foldi [...]
Klhl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123701Kelch-like protein 3; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts [...]
Prrt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123751Proline-rich transmembrane protein 4.
Apbb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123752Amyloid-beta A4 precursor protein-binding family B member 2; May modulate the internalization of amyloid-beta precursor protein.
Sucla2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123765Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synt [...]
2700081O15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000123773Uncharacterized protein C11orf95 homolog.
Ankmy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123787Ankyrin repeat and MYND domain-containing protein 1.
Psme2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123798Proteasome (prosome, macropain) activator subunit 2 (PA28 beta).
2010300C02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000123803RIKEN cDNA 2010300C02 gene.
Zfp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123810Zinc finger protein 9.
Gcsam protein networkhttps://string-db.org/network/10090.ENSMUSP00000123853Germinal center-associated signaling and motility protein; Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive re [...]
Dcaf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123865DDB1- and CUL4-associated factor 1; Acts both as a substrate recognition component of E3 ubiquitin-protein ligase complexes and as an atypical serine/threonine- protein kinase, playing key roles [...]
Pcmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123866Protein-L-isoaspartate(D-aspartate) O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl and D- aspartyl residues in peptides and proteins that result from spontaneous decomp [...]
Ear10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123872Eosinophil-associated, ribonuclease A family, member 10; Belongs to the pancreatic ribonuclease family.
Esp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123886Exocrine gland-secreted peptide 1; Male-specific phermone which is recognized by the Vmn2r116/V2rp5 receptor in the vomeronasal organ (VNO) and enhances female sexual receptive behavior (lordosis [...]
Selp protein networkhttps://string-db.org/network/10090.ENSMUSP00000123924P-selectin; Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocy [...]
Cd46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123931Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
Alg12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123935Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2) [...]
Nat8f7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123947N-acetyltransferase family 8 member 7; Has histone acetyltransferase activity in vitro, with specificity for histone H4.
Gm6619 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123949Predicted gene 6619.
Zfp27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123953Zinc finger protein 27; May be involved in transcriptional regulation.
Zfp579 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123963Zinc finger protein 579; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Chit1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123979Chitotriosidase-1; Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens (By similarity). Belongs to the glycosyl hydrolase 18 family. [...]
Glipr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123990Glioma pathogenesis-related protein 1.
Gm21970 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123997Predicted gene 21970.
Hmga2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000123998High mobility group protein HMGI-C; Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiot [...]
Fhit protein networkhttps://string-db.org/network/10090.ENSMUSP00000124017Bis(5'-adenosyl)-triphosphatase; Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremel [...]
Pappa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124022Pappalysin 2.
4933434E20Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000124028Uncharacterized protein C1orf43 homolog.
Ttc16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124031Tetratricopeptide repeat protein 16.
Wdr41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124033WD repeat-containing protein 41; Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. The C9orf72-SM [...]
Osgep protein networkhttps://string-db.org/network/10090.ENSMUSP00000124039Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) i [...]
Ubn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124043Ubinuclein-2.
Slc30a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124047Zinc transporter 9; Acts as a zinc transporter involved in intracellular zinc homeostasis (By similarity). Functions as a secondary coactivator for nuclear receptors by cooperating with p160 coac [...]
Sirpa protein networkhttps://string-db.org/network/10090.ENSMUSP00000124048Tyrosine-protein phosphatase non-receptor type substrate 1; Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other bindin [...]
Reln protein networkhttps://string-db.org/network/10090.ENSMUSP00000124052Reelin; Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affe [...]
Nbeal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124056Neurobeachin-like 1.
Snx31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124063Sorting nexin-31; May be involved in protein trafficking. Belongs to the sorting nexin family.
Vmn2r89 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124065Putative pheromone receptor.
Rdh11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124066Retinol dehydrogenase 11; Retinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9- cis, 11-cis and all-trans-retinol, and to a lesser extent on 13-cis- retinol (B [...]
B3gat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124067Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan bios [...]
Pde8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000124068High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May b [...]
Zfp26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124075Zinc finger protein 26; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Aoc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124085Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune r [...]
Zfp609 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124089Zinc finger protein 609; Transcription factor, which activates RAG1, and possibly RAG2, transcription. Through the regulation of RAG1/2 expression, may regulate thymocyte maturation. Along with N [...]
Vgll2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124091Transcription cofactor vestigial-like protein 2; May act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles.
Usp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124093Ubiquitin carboxyl-terminal hydrolase 7; Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN, KMT2E and DAXX. Together with DAXX, prevents MDM2 [...]
Pitpnm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124111Membrane-associated phosphatidylinositol transfer protein 2; Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions (By similarity [...]
Cadm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124119Cell adhesion molecule 1; Mediates homophilic cell-cell adhesion in a Ca(2+)- independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent mann [...]
Tle3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124131Transducin-like enhancer protein 3; Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members [...]
Hipk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124133Homeodomain-interacting protein kinase 2; Serine/threonine-protein kinase involved in transcription regulation, p53/TP53-mediated cellular apoptosis and regulation of the cell cycle. Acts as a co [...]
A630001G21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000124137RIKEN cDNA A630001G21 gene.
Filip1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000124179Filamin A-interacting protein 1-like; Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation a [...]
Herpud1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124201Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein; Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degra [...]
Dlx6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124204Homeobox protein DLX-6; Belongs to the distal-less homeobox family.
Wtap protein networkhttps://string-db.org/network/10090.ENSMUSP00000124205Pre-mRNA-splicing regulator WTAP; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency [...]
Mettl11b protein networkhttps://string-db.org/network/10090.ENSMUSP00000124211Alpha N-terminal protein methyltransferase 1B; Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator [...]
Parp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124258Protein mono-ADP-ribosyltransferase PARP4; Mono-ADP-ribosyltransferase that mediates mono-ADP- ribosylation of target proteins.
Aptx protein networkhttps://string-db.org/network/10090.ENSMUSP00000124264Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at b [...]
Unc93b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124272Protein unc-93 homolog B1; Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of T [...]
Hmgn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124278High mobility group nucleosome-binding domain-containing protein 3; Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA [...]
Arhgef38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124280Rho guanine nucleotide exchange factor 38; May act as a guanine-nucleotide releasing factor.
Kctd17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124290Potassium channel tetramerisation domain-containing 17.
Naa50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124291N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity: able to acetylate th [...]
Rnf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124293E3 ubiquitin-protein ligase RNF6; E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regu [...]
Selenop protein networkhttps://string-db.org/network/10090.ENSMUSP00000124305Selenoprotein P; Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium (By similarity). May supply seleni [...]
Ssh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124312Protein phosphatase Slingshot homolog 1; Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequ [...]
Tbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000124317TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional ste [...]
Cntn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124327Contactin-5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal [...]
Arl4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000124344ADP-ribosylation factor-like protein 4C; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleot [...]
Greb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124348Protein GREB1; May play a role in estrogen-stimulated cell proliferation. Belongs to the GREB1 family.
Panx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124354Pannexin-2; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
Mroh8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124362Maestro heat-like repeat family member 8.
Ttc26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124369Intraflagellar transport protein 56; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary [...]
Ctnna2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124376Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Required for proper re [...]
Nxpe5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124381Neurexophilin and PC-esterase domain family, member 5.
Lrrc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124394Leucine-rich repeat-containing protein 9.
Fancc protein networkhttps://string-db.org/network/10090.ENSMUSP00000124406Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair [...]
C6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124417Complement component 6.
Thnsl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124423Threonine synthase-like 2; Acts as a catabolic phospho-lyase on both gamma- and beta- phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate. [...]
Gpc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124459Secreted glypican-2; Cell surface proteoglycan that bears heparan sulfate. May fulfill a function related to the motile behaviors of developing neurons (By similarity); Belongs to the glypican fa [...]
Kif26b protein networkhttps://string-db.org/network/10090.ENSMUSP00000124462Kinesin-like protein KIF26B; Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by inter [...]
Lhfpl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124470LHFPL tetraspan subfamily member 4 protein; Plays a role in the regulation of inhibitory synapse formation and function by being involved in maintening gamma- aminobutyric acid receptors (GABAARs [...]
Sv2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000124473Synaptic vesicle glycoprotein 2C; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates ves [...]
Wdr63 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124475WD repeat domain 63.
Tcerg1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000124476Transcription elongation regulator 1-like protein.
Cyb5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000124480Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases. It is also involved in several steps of the sterol biosynthe [...]
Stau2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124505Double-stranded RNA-binding protein Staufen homolog 2; RNA-binding protein required for the microtubule-dependent transport of neuronal RNA from the cell body to the dendrite. As protein synthesi [...]
H3f3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000124509H3.3 histone A.
Hephl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124518Ferroxidase HEPHL1; Is a copper-binding glycoprotein with ferroxidase activity. It oxidizes Fe(2+) to Fe(3+) without releasing radical oxygen species. May be involved in the regulation of intrace [...]
Prrt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124520Proline-rich transmembrane protein 2; As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presyna [...]
Cycs protein networkhttps://string-db.org/network/10090.ENSMUSP00000124523Cytochrome c, somatic.
Fbxo41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124524F-box only protein 41; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Cldn16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124528Claudin-16; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorpt [...]
Pag1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124529Phosphoprotein associated with glycosphingolipid-enriched microdomains 1; Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin [...]
Tmprss11e protein networkhttps://string-db.org/network/10090.ENSMUSP00000124534Transmembrane protease serine 11E non-catalytic chain; Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position. Belongs to th [...]
Eif4g2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124551Eukaryotic translation initiation factor 4 gamma 2; Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by [...]
Manf protein networkhttps://string-db.org/network/10090.ENSMUSP00000124562Mesencephalic astrocyte-derived neurotrophic factor; Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neuro [...]
Alkbh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124565Nucleic acid dioxygenase ALKBH1; Dioxygenase that acts as on nucleic acids, such as DNA and tRNA. Requires molecular oxygen, alpha-ketoglutarate and iron. A number of activities have been describ [...]
Slc37a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124569Glucose-6-phosphate exchanger SLC37A2; Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and transl [...]
Adra1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000124570Alpha-1A adrenergic receptor; This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect i [...]
Asl protein networkhttps://string-db.org/network/10090.ENSMUSP00000124579Argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
Clca3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000124581Chloride channel accessory 3B.
Wdr26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124592WD repeat-containing protein 26; G-beta-like protein involved in cell signal transduction. Acts as a negative regulator in MAPK signaling pathway. Functions as a scaffolding protein to promote G [...]
Cnih3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124611Protein cornichon homolog 3; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modula [...]
Wars protein networkhttps://string-db.org/network/10090.ENSMUSP00000124625Tryptophan--tRNA ligase, cytoplasmic; T1-TrpRS has aminoacylation activity while T2-TrpRS lacks it. T1-TrpRS and T2-TrpRS possess angiostatic activity. T2-TrpRS inhibits fluid shear stress-activa [...]
Mrgpra2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000124631MAS-related GPR, member A2A; Belongs to the G-protein coupled receptor 1 family.
Glis3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124635Zinc finger protein GLIS3; Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5'-GACCACCCAC-3'.
Abcg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124647ATP-binding cassette transporter sub-family G member 4.
Il21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124668Interleukin-21; Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role i [...]
Sh2d6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124673SH2 domain-containing protein 6.
Kif6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124674Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Ms4a6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000124685Membrane-spanning 4-domains subfamily A member 6B; May be involved in signal transduction as a component of a multimeric receptor complex.
Setdb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124696Histone-lysine N-methyltransferase SETDB2; Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 ( [...]
Pheta2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124703Sesquipedalian-2; Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
Grip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124709Glutamate receptor-interacting protein 2.
Mycbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124710E3 ubiquitin-protein ligase MYCBP2; Atypical E3 ubiquitin-protein ligase which specifically mediates ubiquitination of threonine and serine residues on target proteins, instead of ubiquitinating [...]
Nwd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124712NACHT and WD repeat domain-containing protein 2.
Commd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124719COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitinatio [...]
Skint1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124737Selection and upkeep of intraepithelial T-cells protein 1; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus. Plays a central role in mediating key epitheli [...]
Pou2f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124738POU domain, class 2, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) an [...]
4930558K02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000124751RIKEN cDNA 4930558K02 gene.
C87414 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124780Expressed sequence C87414.
Pip4p1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124782Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P) (By [...]
Nwd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124804NACHT domain- and WD repeat-containing protein 1; May play a role in the control of androgen receptor (AR) protein steady-state levels.
Hr protein networkhttps://string-db.org/network/10090.ENSMUSP00000124816Lysine-specific demethylase hairless; Histone demethylase that specifically demethylates both mono- and dimethylated 'Lys-9' of histone H3. May act as a transcription regulator controlling hair b [...]
Commd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124819COMM domain-containing protein 2; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B.
Tra2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000124846Transformer-2 protein homolog beta; Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively w [...]
Cmtm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124855CKLF-like MARVEL transmembrane domain-containing 1.
Zmiz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124863Zinc finger MIZ domain-containing protein 1; Acts as transcriptional coactivator. Increases ligand- dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR act [...]
Rc3h1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124871Roquin-1; Post-transcriptional repressor of mRNAs containing a conserved stem loop motif, called constitutive decay element (CDE), which is often located in the 3'-UTR, as in HMGXB3, ICOS, IER3, [...]
Sphkap protein networkhttps://string-db.org/network/10090.ENSMUSP00000124872A-kinase anchor protein SPHKAP; Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular [...]
Ermp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124881Endoplasmic reticulum metallopeptidase 1; Within the ovary, required for the organization of somatic cells and oocytes into discrete follicular structures. Belongs to the peptidase M28 family.
Clec2i protein networkhttps://string-db.org/network/10090.ENSMUSP00000124910C-type lectin domain family 2 member I; Inhibits osteoclast formation. Receptor for KLRB1F. Enhances T-cell activation. Plays a role in splenocyte activation, T-cell responses and IL-2 production [...]
E330034G19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000124917RIKEN cDNA E330034G19 gene.
Gm20671 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124923Predicted gene 20671.
Zfp957 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124930Zinc finger protein 957.
Impdh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124931Inosine-5'-monophosphate dehydrogenase 1; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthe [...]
Kcnc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124938Potassium voltage-gated channel subfamily C member 1; Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in r [...]
Spopfm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124942Speckle-type BTB/POZ protein family member 2.
Ciart protein networkhttps://string-db.org/network/10090.ENSMUSP00000124943Circadian-associated transcriptional repressor; Transcriptional repressor which forms a negative regulatory component of the circadian clock and acts independently of the circadian transcriptiona [...]
Fnbp1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000124947Formin-binding protein 1-like; Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bis [...]
Prkg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124963cGMP-dependent protein kinase 2; Crucial regulator of intestinal secretion and bone growth. Phosphorylates and activates CFTR on the plasma membrane. Plays a key role in intestinal secretion by r [...]
Cpsf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124966Cleavage and polyadenylation specificity factor subunit 4; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recog [...]
Smok2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000124967Sperm motility kinase 2B; May play a role in sperm motility, especially in the regulation of flagellar function.
Slc9c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000124969Sodium/hydrogen exchanger 10; Sperm-specific sodium/hydrogen exchanger involved in intracellular pH regulation of spermatozoa. Required for sperm motility and fertility. Involved in sperm cell hy [...]
Ccdc85a protein networkhttps://string-db.org/network/10090.ENSMUSP00000124972Coiled-coil domain-containing protein 85A; May play a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family; Belongs to the CCDC85 [...]
Srrm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125003Serine/arginine repetitive matrix protein 1; Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing [...]
Cfap43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125007Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP43 family.
Gm8113 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125038Predicted gene 8113.
Adck5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125055Uncharacterized aarF domain-containing protein kinase 5; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosp [...]
Kcnab2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125058Voltage-gated potassium channel subunit beta-2; Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of ne [...]
Ces4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000125062Carboxylesterase 4A; Probable carboxylesterase; Belongs to the type-B carboxylesterase/lipase family.
Cacna1i protein networkhttps://string-db.org/network/10090.ENSMUSP00000125063Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calc [...]
Col22a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125069Collagen, type XXII, alpha 1.
Tnik protein networkhttps://string-db.org/network/10090.ENSMUSP00000125081Traf2 and NCK-interacting protein kinase; Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to acti [...]
Ecel1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125096Endothelin-converting enzyme-like 1; May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides; Belongs to the peptidase M13 family.
Oprk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125105Kappa-type opioid receptor; G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also function [...]
A930017K11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000125106RIKEN cDNA A930017K11 gene.
Slc14a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125114Urea transporter 1; Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through w [...]
Sh2d1b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125121SH2 domain-containing protein 1B2; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family. In SLAM signaling may cooperate with Sh2d1a/SAP. Plays [...]
A530032D15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000125122RIKEN cDNA A530032D15Rik gene.
5430401F13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000125129RIKEN cDNA 5430401F13 gene.
Rasgrp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125137RAS guanyl-releasing protein 4; Functions as a cation- and diacylglycerol (DAG)-regulated nucleotide exchange factor activating Ras through the exchange of bound GDP for GTP. May function in mast [...]
Mfap3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000125139Microfibrillar-associated protein 3-like; May participate in the nuclear signaling of EGFR and MAPK1/ERK2.
Kcnip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125142Kv channel-interacting protein 2; Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate o [...]
Lypd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125149Ly6/PLAUR domain-containing protein 1; Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity fo [...]
Med6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125156Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Me [...]
Tmem92 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125159Transmembrane protein 92.
Tcf19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125167Transcription factor 19-like protein.
Atp5o-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125172ATP synthase, H+-transporting, mitochondrial F1 complex, O subunit.
Fgd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125174FYVE, RhoGEF and PH domain-containing protein 4; Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates MAPK8 (By similarity). [...]
Lrrtm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125207Leucine-rich repeat transmembrane neuronal protein 1; Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.
Nos1ap protein networkhttps://string-db.org/network/10090.ENSMUSP00000125251Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein; Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex [...]
Zbtb37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125253Zinc finger and BTB domain-containing 37.
Cabp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125255Calcium-binding protein 2; Required for sound encoding at inner hair cells (IHCs) synapses, likely via inhibition of the inactivation of voltage-gated calcium channel of type 1.3 (Cav1.3) in the [...]
Zfat protein networkhttps://string-db.org/network/10090.ENSMUSP00000125257Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulat [...]
Fut10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125265Alpha-(1,3)-fucosyltransferase 10; Probable fucosyltransferase.
Spopfm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125267Speckle-type BTB/POZ protein family member 3.
Ap1s3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125268AP-1 complex subunit sigma-3; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP co [...]
Nxph1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125274Neurexophilin-1; May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins; Belongs to the neurexophilin family.
Tc2n protein networkhttps://string-db.org/network/10090.ENSMUSP00000125288Tandem C2 domains nuclear protein.
Zfp677 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125295Zinc finger protein 677.
Riox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125297Ribosomal oxygenase 2; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 ( [...]
Nsmce4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000125300Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs [...]
Ano2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125303Anoctamin-2; Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor- sensing receptors (OSRs), leading to an increase in [...]
Exoc6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000125312Exocyst complex component 6B; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Tmem167 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125314Protein kish-A; Involved in the early part of the secretory pathway.
Galnt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125315Polypeptide N-acetylgalactosaminyltransferase 4; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threon [...]
Cdk5r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125322Cyclin-dependent kinase 5 activator 2; Activator of CDK5/TPKII; Belongs to the cyclin-dependent kinase 5 activator family.
4933417A18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000125324Uncharacterized protein C6orf201 homolog.
Zfp949 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125325Zinc finger protein 949.
Lmo3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125335LIM domain only protein 3.
Slirp protein networkhttps://string-db.org/network/10090.ENSMUSP00000125341SRA stem-loop-interacting RNA-binding protein, mitochondrial; RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediate [...]
Gtpbp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125352GTP-binding protein 8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Phf21b protein networkhttps://string-db.org/network/10090.ENSMUSP00000125355PHD finger protein 21B.
Tepp protein networkhttps://string-db.org/network/10090.ENSMUSP00000125362Testis, prostate and placenta-expressed protein.
Plod2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125373Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2; Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units a [...]
Maf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125387Repressor of RNA polymerase III transcription MAF1 homolog; Plays a role in the repression of RNA polymerase III-mediated transcription in response to changing nutritional, environmental and cell [...]
Cul2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125403Cullin-2; Core component of multiple cullin-RING-based ECS (ElonginB/C- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. ECS co [...]
Stxbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125405Syntaxin-binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-eth [...]
Nrxn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125407Neurexin-1; Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have [...]
Gm7247 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125409Predicted gene 7247.
Mob4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125415MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family.
Zfp316 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125416Zinc finger protein 316; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Tyw5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125427tRNA wybutosine-synthesizing protein 5; tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at t [...]
Exoc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125434Exocyst complex component 5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Ciapin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125451Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain funct [...]
Pard3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125453Partitioning defective 3 homolog; Adapter protein involved in asymmetrical cell division and cell polarization processes (By similarity). Seems to play a central role in the formation of epitheli [...]
Acat3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125454Acetyl-Coenzyme A acetyltransferase 3; Belongs to the thiolase-like superfamily. Thiolase family.
Vwa3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000125460Von Willebrand factor A domain-containing 3B.
Fam83a protein networkhttps://string-db.org/network/10090.ENSMUSP00000125464Protein FAM83A; Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. Activates both RAS/MAPK and PI3K/AKT/TOR signaling cascades downstream of EG [...]
Tex47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125471Testis-expressed protein 47.
Man2c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125478Alpha-mannosidase 2C1; Cleaves alpha 1,2-, alpha 1,3-, and alpha 1,6-linked mannose residues from glycoproteins. Involved in the degradation of free oligosaccharides in the cytoplasm.
Txndc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125491Thioredoxin domain-containing protein 9; Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein folding, including that of actin or tubulin.
Hgd protein networkhttps://string-db.org/network/10090.ENSMUSP00000125492Homogentisate 1,2-dioxygenase.
Rad52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125502DNA repair protein RAD52 homolog; Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-strande [...]
Atp5j2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125504ATP synthase subunit f, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane whic [...]
Tbc1d4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125509TBC1 domain family member 4; May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membra [...]
C1s1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125531Complement C1s-A subcomponent heavy chain; C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r a [...]
Ubl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125540Ubiquitin-like protein 5.
Psma3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125548Proteasome subunit alpha type-3; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles w [...]
Hint3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125552Histidine triad nucleotide-binding protein 3; Hydrolyzes phosphoramidate and acyl-adenylate substrates.
Bud31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125564Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity.
Phc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125580Polyhomeotic-like protein 1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, includi [...]
Armc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125583Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function. Involved in axonemal central pair complex assembly and/or stability.
Speer4e protein networkhttps://string-db.org/network/10090.ENSMUSP00000125587Spermatogenesis-associated glutamate (E)-rich protein 4e.
Gstt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125604Glutathione S-transferase theta-4; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Theta family.
Gm28038 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125607Predicted gene, 28038.
Gm28048 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125609COMM domain-containing 1B.
Srgn protein networkhttps://string-db.org/network/10090.ENSMUSP00000125622Serglycin; Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tis [...]
Ro60 protein networkhttps://string-db.org/network/10090.ENSMUSP0000012562360 kDa SS-A/Ro ribonucleoprotein; RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of thes [...]
Cnot11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125638CCR4-NOT transcription complex subunit 11; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA d [...]
AI837181 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125651UPF0696 protein C11orf68 homolog.
Gfm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125656Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in co [...]
Hps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125662Hermansky-Pudlak syndrome 1 protein homolog; Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, conv [...]
Gng2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125697Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling sy [...]
Fer1l6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125718Fer-1-like 6 (C. elegans).
Ppp3cb protein networkhttps://string-db.org/network/10090.ENSMUSP00000125722Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform; Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracell [...]
Usf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125729Upstream stimulatory factor 1; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
Cfap77 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125742Cilia and flagella-associated protein 77.
Rnf123 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125745E3 ubiquitin-protein ligase RNF123; Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Promotes the ubiquitination and proteasome- mediated degradation of CDKN1B which [...]
Krr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125746KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity).
Trmt10a protein networkhttps://string-db.org/network/10090.ENSMUSP00000125749tRNA methyltransferase 10 homolog A; S-adenosyl-L-methionine-dependent guanine N(1)- methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs. Probably n [...]
Pdcd10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125752Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, [...]
Crb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125760Protein crumbs homolog 3; Involved in the establishment of cell polarity in mammalian epithelial cells. Regulates the morphogenesis of tight junctions (By similarity).
Matr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125761Matrin-3; May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a ro [...]
Serpine3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125769Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3; Belongs to the serpin family.
Lck protein networkhttps://string-db.org/network/10090.ENSMUSP00000125777Proto-oncogene tyrosine-protein kinase LCK; Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the functi [...]
Mocs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125797Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the [...]
Mtm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125798Myotubularin; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate ph [...]
Loxl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125803Lysyl oxidase homolog 4; May modulate the formation of a collagenous extracellular matrix.
Gm11239 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125805Predicted gene 11239.
Rpl10-ps3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125806Ribosomal protein L10, pseudogene 3.
Fancf protein networkhttps://string-db.org/network/10090.ENSMUSP00000125812Fanconi anemia group F protein; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in [...]
Vmn2r57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125817Vomeronasal 2, receptor 57.
Vmn1r123 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125823Taste receptor type 2.
Ptprh protein networkhttps://string-db.org/network/10090.ENSMUSP00000125833Receptor-type tyrosine-protein phosphatase H; Protein phosphatase that may contribute to contact inhibition of cell growth and motility by mediating the dephosphorylation of focal adhesion-associ [...]
Eps8l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125840Epidermal growth factor receptor kinase substrate 8-like protein 1; Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton (By [...]
H2al1i protein networkhttps://string-db.org/network/10090.ENSMUSP00000125841Histone H2A-like 1; Atypical histone H2A which can replace conventional H2A in some nucleosomes and may play a role during spermatogenesis. Nucleosomes wrap and compact DNA into chromatin, limiti [...]
Slc16a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125846Monocarboxylate transporter 4; Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-cha [...]
Gm5916 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125855Predicted gene 5916.
Cpeb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125857Cytoplasmic polyadenylation element-binding protein 2; May play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid spermatids. Binds to poly(U) RNA oligomers [...]
Il12b protein networkhttps://string-db.org/network/10090.ENSMUSP00000125867Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the productio [...]
Six2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125871Homeobox protein SIX2; Transcription factor that plays an important role in the development of several organs, including kidney, skull and stomach. During kidney development, maintains cap mesenc [...]
Ccdc58 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125874Coiled-coil domain-containing protein 58; Belongs to the CCDC58 family.
Gm7970 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125877Predicted gene 7970.
Mpp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125880MAGUK p55 subfamily member 6; Belongs to the MAGUK family.
Spdya protein networkhttps://string-db.org/network/10090.ENSMUSP00000125912Speedy protein A; Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2. Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing [...]
Mad2l1bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000125915MAD2L1-binding protein; May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 comple [...]
Glyatl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125916Glycine-N-acyltransferase-like protein 3; Catalyzes the conjugation of long-chain fatty acyl-CoA thioester and glycine to produce long-chain N-(fatty acyl)glycine, an intermediate in the primary [...]
Paqr7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125932Membrane progestin receptor alpha; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(i) mediated pathway. May be involved in oocyte maturation. Involved i [...]
Evi2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000125936Protein EVI2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor.
Minar2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000125952Major intrinsically disordered NOTCH2-binding receptor 1-like homolog; Belongs to the MINAR family.
Mcm3ap protein networkhttps://string-db.org/network/10090.ENSMUSP00000125960Germinal-center associated nuclear protein; As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (By similarity). Through the acetylati [...]
1600012H06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000125970UPF0669 protein C6orf120 homolog; May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes; Belongs to the UPF0669 family.
Mb protein networkhttps://string-db.org/network/10090.ENSMUSP00000125995Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
Cst12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126008Cystatin-12; May play a specialized role in spermatogenesis.
Cdk6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126024Cyclin-dependent kinase 6; Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation; promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with [...]
Sumf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126036Inactive C-alpha-formylglycine-generating enzyme 2; Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activ [...]
Wdr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126061tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Non-catalytic component of a methyltransferase complex required for the formation of N(7)-methylguanine in a subset of RNA speci [...]
Zfp185 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126066Zinc finger protein 185; May be involved in the regulation of cellular proliferation and/or differentiation.
Ncoa4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126071Nuclear receptor coactivator 4.
Tusc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126080Tumor suppressor candidate 3; Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked olig [...]
Pik3c2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000126092Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha; Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that [...]
Chrm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126103Muscarinic acetylcholine receptor M1; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modu [...]
Acvr2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000126108Activin receptor type-2B; Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or [...]
Gabra6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126114Gamma-aminobutyric acid receptor subunit alpha-6; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor [...]
Cyb5r4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126119Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress [...]
Arf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126120ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces [...]
Mcm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126135DNA replication licensing factor MCM5; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiat [...]
Lifr protein networkhttps://string-db.org/network/10090.ENSMUSP00000126137Leukemia inhibitory factor receptor; Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to recepto [...]
Ccnd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126141G1/S-specific cyclin-D3; Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the [...]
B3gnt5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126157Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase; Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on g [...]
Vmn2r3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126165Vomeronasal 2, receptor 3.
Cldn20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126169Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
Ube2f protein networkhttps://string-db.org/network/10090.ENSMUSP00000126173NEDD8-conjugating enzyme UBE2F; Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E [...]
Rgmb protein networkhttps://string-db.org/network/10090.ENSMUSP00000126177RGM domain family member B; Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system. Acts as a bone morphogenetic protein (BMP) [...]
Mchr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126191Melanin-concentrating hormone receptor 1; Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrol [...]
Ptbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126192Polypyrimidine tract-binding protein 1; Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre- mRNA during muscle cell dif [...]
Dtnb protein networkhttps://string-db.org/network/10090.ENSMUSP00000126194Dystrobrevin beta.
Krt78 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126197Keratin 78; Belongs to the intermediate filament family.
Gm17124 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126204Predicted gene 17124.
Rnf14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126205E3 ubiquitin-protein ligase RNF14; Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which co [...]
Fam169a protein networkhttps://string-db.org/network/10090.ENSMUSP00000126209Soluble lamin-associated protein of 75 kDa.
Gm14569 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126231Acrosomal protein KIAA1210.
Tox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126243TOX high mobility group box family member 2.
Cdr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126250Cerebellar degeneration related antigen 1.
Krtap20-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126264Keratin-associated protein 20-2.
Kars protein networkhttps://string-db.org/network/10090.ENSMUSP00000126268Lysine--tRNA ligase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred [...]
Ptprk protein networkhttps://string-db.org/network/10090.ENSMUSP00000126279Receptor-type tyrosine-protein phosphatase kappa; Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR si [...]
Chst3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126281Carbohydrate sulfotransferase 3; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosa [...]
E430018J23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000126288RIKEN cDNA E430018J23 gene.
Rps13 protein networkhttps://string-db.org/network/10090.ENSMUSP0000012629440S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.
Timm9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126298Mitochondrial import inner membrane translocase subunit Tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mit [...]
Ascc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126301Activating signal cointegrator 1 complex subunit 1; Plays a role in DNA damage repair as component of the ASCC complex. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactiva [...]
Mgat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126303Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-gly [...]
Gm7951 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126311Predicted gene 7951.
Rfx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126313Transcription factor RFX3; Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocili [...]
Dnajc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126321DnaJ homolog subfamily C member 1; May modulate protein synthesis.
A930033H14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000126322RIKEN cDNA A930033H14 gene.
Zfp148 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126338Zinc finger protein 148; Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhanc [...]
Fignl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126340Fidgetin-like protein 1; Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-depe [...]
Omt2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000126342Oocyte maturation, alpha.
Rnps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126345RNA-binding protein with serine-rich domain 1; Part of pre- and post-splicing multiprotein mRNP complexes. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) d [...]
Pfpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000126346Pore-forming protein-like.
Gm21319 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126351Predicted gene, 21319; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S [...]
Chd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126352Chromodomain-helicase-DNA-binding protein 2; DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of his [...]
Rbm7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126374RNA-binding protein 7; RNA-binding subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that functions as an RNA exosome cofactor that directs a subset of non-coding short- [...]
Bcr protein networkhttps://string-db.org/network/10090.ENSMUSP00000126377Breakpoint cluster region protein; Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein (GAP) [...]
Vmn2r94 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126386Vomeronasal 2, receptor 94.
Serpinh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126390Serpin H1; Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.
Panx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126405Pannexin-1; Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis (By similarity).
Racgap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126417Rac GTPase-activating protein 1; Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation duri [...]
Ms4a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126422B-lymphocyte antigen CD20; B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of [...]
Mfsd4b5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126439Major facilitator superfamily domain-containing 4B5.
Acot1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126448Acyl-coenzyme A thioesterase 1; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating intracellular leve [...]
Fam83h protein networkhttps://string-db.org/network/10090.ENSMUSP00000126453Protein FAM83H; May play a major role in the structural organization and calcification of developing enamel. May play a role in keratin cytoskeleton disassembly by recruiting CSNK1A1 to keratin f [...]
Acox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126464Peroxisomal acyl-coenzyme A oxidase 2; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycoprostanic acids (By similarity). Capable of oxidizing short as well as long chai [...]
Luzp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126473Leucine zipper protein 4.
Ccdc159 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126474Coiled-coil domain-containing protein 159.
Fam220a protein networkhttps://string-db.org/network/10090.ENSMUSP00000126480Protein FAM220A; May negatively regulate STAT3.
Rnf168 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126484E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ub [...]
Fam71f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126496Protein FAM71F1; Belongs to the FAM71 family.
Adamts9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126498A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9.
Cfap100 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126515Cilia- and flagella-associated protein 100; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP100 family.
Arih1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126531E3 ubiquitin-protein ligase ARIH1; E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3. Acts as an atypical E3 ubiq [...]
Vmn2r106 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126534Vomeronasal 2, receptor 106.
H60c protein networkhttps://string-db.org/network/10090.ENSMUSP00000126536Histocompatibility antigen 60c; Ligand for the KLRK1 immunosurveillance receptor. Binding to KLRK1 stimulates cell lysis in vitro.
Ubtfl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126540Upstream-binding factor 1-like protein 1; Essential for proliferation of the inner cell mass and trophectodermal cells in peri-implantation development.
Stk35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126541Serine/threonine-protein kinase 35.
Gm9603 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126547Predicted gene 3542.
Vmn2r102 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126559Vomeronasal 2, receptor 102.
Lrrcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126560Leucine-rich repeat and coiled-coil domain-containing protein 1; Required for the organization of the mitotic spindle. Maintains the structural integrity of centrosomes during mitosis (By similar [...]
Lsm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126565U6 snRNA-associated Sm-like protein LSm5; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatal [...]
H2al2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000126567Histone H2A; Belongs to the histone H2A family.
Trim43b protein networkhttps://string-db.org/network/10090.ENSMUSP00000126594Tripartite motif-containing protein 43B.
Vmn2r86 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126596Vomeronasal 2, receptor 86.
Arhgef12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126598Rho guanine nucleotide exchange factor 12; May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchang [...]
Ggps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126603Geranylgeranyl pyrophosphate synthase; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and gerany [...]
R3hdm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126608R3H domain-containing protein 2.
Zyx protein networkhttps://string-db.org/network/10090.ENSMUSP00000126622Zyxin; Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. [...]
Gm21962 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126626Predicted gene, 21962.
Zfp516 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126629Zinc finger protein 516; Transcriptional regulator that binds to the promoter and activates the transcription of genes promoting brown adipose tissue (BAT) differentiation. Among brown adipose ti [...]
Gm5624 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126636Predicted gene 5624.
Vmn2r90 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126650Vomeronasal 2, receptor 90.
Kcnb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126656Potassium voltage-gated channel subfamily B member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and smooth mus [...]
Zfp712 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126665Zinc finger protein 712.
Zfp692 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126674Zinc finger protein 692; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Vmn2r23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126682Vomeronasal 2, receptor 23.
Mymx protein networkhttps://string-db.org/network/10090.ENSMUSP00000126690Protein myomixer; Myoblast-specific protein that mediates myoblast fusion, an essential step for the formation of multi-nucleated muscle fibers. Involved in membrane fusion downstream of the lipi [...]
Dpy30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126702Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys- 4' methylation represents a specific t [...]
4833427G06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000126725UPF0722 protein C11orf88 homolog; Belongs to the UPF0722 family.
Dctd protein networkhttps://string-db.org/network/10090.ENSMUSP00000126733Deoxycytidylate deaminase; Supplies the nucleotide substrate for thymidylate synthetase.
Tecpr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126749Tectonin beta-propeller repeat-containing 2.
Gm20538 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126763Predicted gene 20538.
BC052040 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126772Protein C15orf41 homolog; Plays a role in erythroid cell differentiation.
Ces2h protein networkhttps://string-db.org/network/10090.ENSMUSP00000126773Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
Senp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126777Sentrin-specific protease 6; Protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. Processes preferentially poly-SUMO2 and poly-SUMO3 chains, but does not efficiently process [...]
Cyp2t4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126779Cytochrome P450, family 2, subfamily t, polypeptide 4.
Defa27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126797Defensin, alpha, 27.
AU018091 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126800Expressed sequence AU018091.
Gpatch11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126814G patch domain-containing protein 11.
S100a14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126821Protein S100-A14; Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apop [...]
Eif5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126825Eukaryotic translation initiation factor 5; Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S rib [...]
Scn2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000126826Sodium channel subunit beta-2; Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the pla [...]
Dnajb11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126828DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substr [...]
Gm3002 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126836Predicted gene 3002.
Slc43a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126838Large neutral amino acids transporter small subunit 4; Sodium-, chloride-, and pH-independent, high affinity transport of large neutral amino acids; Belongs to the SLC43A transporter (TC 2.A.1.44 [...]
Myh7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126840Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute [...]
Zfp219 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126854Zinc finger protein 219; Transcriptional regulator. Recognizes and binds 2 copies of the core DNA sequence motif 5'-GGGGG-3'. Binds to the HMGN1 promoter and may repress HMGN1 expression (By simi [...]
Sgk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126861Serine/threonine-protein kinase Sgk3; Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, sur [...]
Zfp595 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126862Regulator of sex-limitation candidate 23.
Vmn2r46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126863Vomeronasal 2, receptor 46.
Ccnt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126874Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the tr [...]
Smim17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126877Small integral membrane protein 17.
Spsb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126878SPRY domain-containing SOCS box protein 3; May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the u [...]
Zfp600 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126879Zinc finger protein 600.
Vmn1r166 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126882Taste receptor type 2.
Vmn2r117 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126885Vomeronasal 2, receptor 117.
Gm10320 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126887Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
Pate8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126891Secreted TFP/Ly-6/uPAR protein PATE-G.
Gm10260 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126892Ribosomal protein S18, pseudogene 6; Belongs to the universal ribosomal protein uS13 family.
Mov10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126897Putative helicase MOV-10; Probable RNA helicase. Required for miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression [...]
Siglec15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126901Sialic acid-binding Ig-like lectin 15.
Taf4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000126909Transcription initiation factor TFIID subunit 4B; Cell type-specific subunit of the general transcription factor TFIID that may function as a gene-selective coactivator in certain cells. TFIID is [...]
Gpr35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126914G-protein coupled receptor 35; Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calc [...]
Abhd14a protein networkhttps://string-db.org/network/10090.ENSMUSP00000126916Protein ABHD14A; Possible role in granule neuron development. Belongs to the AB hydrolase superfamily. ABHD14 family.
Vmn2r74 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126917Vomeronasal 2, receptor 74.
2310050C09Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000126921RIKEN cDNA 2310050C09 gene.
Serpina16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126933Serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16; Belongs to the serpin family.
Elf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126941ETS-related transcription factor Elf-5; Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation (By similarity). Binds to DNA seq [...]
Gm10409 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126947Predicted gene 10409.
Gm7980 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126952Predicted gene 7980.
Vmn2r8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126953Vomeronasal 2, receptor 8.
Cnmd protein networkhttps://string-db.org/network/10090.ENSMUSP00000126958Leukocyte cell-derived chemotaxin 1; Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the gro [...]
3830406C13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000126960Uncharacterized protein C3orf14 homolog.
Vmn2r58 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126966Vomeronasal 2, receptor 58.
Gm9008 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126976Predicted pseudogene 9008.
Vmn2r53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126979Vomeronasal 2, receptor 53.
Dlgap4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126980Disks large-associated protein 4; May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoske [...]
Dusp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126984Dual specificity protein phosphatase 7; Dual specificity protein phosphatase. Shows high activity towards MAPK1/ERK2 (By similarity). Also has lower activity towards MAPK14 and MAPK8 (By similari [...]
Bmp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000126999Bone morphogenetic protein 6; Induces cartilage and bone formation; Belongs to the TGF-beta family.
Vmn1r251 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127012Vomeronasal type-1 receptor.
Irf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127021Interferon regulatory factor 5; Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling (B [...]
Mrgprx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127022Mas-related G-protein coupled receptor member X2; Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sen [...]
Ccr9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127024C-C chemokine receptor type 9; Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level.
Inafm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127027InaF motif-containing 1.
Eif4a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127034Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current mode [...]
Gm3043 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127050Predicted gene 3043.
Mybpc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127070Myosin-binding protein C, cardiac-type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F- actin and native thin [...]
Gbgt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127071Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1; Catalyzes the formation of Forssman glycolipid via the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to GalNAcb-1,3Gala- [...]
Sap25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127076Histone deacetylase complex subunit SAP25; Involved in the transcriptional repression mediated by the mSIN3A but not the N-CoR corepressor complex.
Nxnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127094Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods.
Myocos protein networkhttps://string-db.org/network/10090.ENSMUSP00000127102Myocilin opposite strand protein.
Runx1t1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127109Protein CBFA2T1; Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and hist [...]
Uroc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127114Urocanate hydratase.
Gm765 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127120Gene model 765, (NCBI).
Vmn1r119 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127126Vomeronasal type-1 receptor.
Gm21293 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127137Predicted gene, 21293.
Pnpla2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127149Patatin-like phospholipase domain-containing protein 2; Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Also has acylglycerol transacylase act [...]
Ear6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127152Eosinophil-associated, ribonuclease A family, member 6; Belongs to the pancreatic ribonuclease family.
Pdgfra protein networkhttps://string-db.org/network/10090.ENSMUSP00000127173Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic d [...]
Gm3072 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127174Predicted gene 3072.
Zfp871 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127178Zinc finger protein 871.
Dennd2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000127187DENN domain-containing protein 2C; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins int [...]
Rfx7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127192Regulatory factor X, 7.
Mapk10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127193Mitogen-activated protein kinase 10; Serine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death. Extracellu [...]
Gm4737 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127198Predicted gene 4737.
Rem2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127199GTP-binding protein REM 2; Binds GTP saturably and exhibits a low intrinsic rate of GTP hydrolysis.
B230217C12Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000127204RIKEN cDNA B230217C12 gene.
C530008M17Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000127212Capping protein inhibiting regulator of actin dynamics; Involved in epithelial cell integrity by acting on the dynamics of the actin cytoskeleton. Positively regulates the actin polymerization, b [...]
Sv2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000127245Synaptic vesicle glycoprotein 2B; Probably plays a role in the control of regulated secretion in neural and endocrine cells. (Microbial infection) Possible receptor for C.botulinum neurotoxin typ [...]
Olfr1564 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127247Olfactory receptor 1564.
Iqsec2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127249IQ motif and SEC7 domain-containing protein 2; Is a guanine nucleotide exchange factor for the ARF GTP- binding proteins; Belongs to the BRAG family.
Mvp protein networkhttps://string-db.org/network/10090.ENSMUSP00000127250Major vault protein; Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role i [...]
Metrn protein networkhttps://string-db.org/network/10090.ENSMUSP00000127275Meteorin; Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. A [...]
Slc7a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127280Cationic amino acid transporter 4; Involved in the transport of the cationic amino acids (arginine, lysine and ornithine); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cati [...]
Cdhr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127292Cadherin-related family member 5; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR2 on adjacent microvilli. Thereby, [...]
Gm13040 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127296Predicted gene 13040.
Btbd9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127300BTB/POZ domain-containing protein 9.
Armcx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127305Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells.
Vmn2r76 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127309Vomeronasal 2, receptor 76.
Lpcat2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000127318Lysophosphatidylcholine acyltransferase 2B; Probable acetyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
Gpat4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127325Glycerol-3-phosphate acyltransferase 4; Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3- phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the [...]
Vldlr protein networkhttps://string-db.org/network/10090.ENSMUSP00000127329Very low-density lipoprotein receptor; Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated p [...]
Rab1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000127330Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle bet [...]
Tmem240 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127341Transmembrane protein 240.
Bend3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127351BEN domain-containing protein 3; Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoyla [...]
C2cd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127368C2 domain-containing protein 2.
Ms4a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127373High affinity immunoglobulin epsilon receptor subunit beta; High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required [...]
Mgll protein networkhttps://string-db.org/network/10090.ENSMUSP00000127374Monoglyceride lipase; Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabi [...]
Gm21977 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127377Predicted gene 21977.
Gm3020 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127384Predicted gene 3020.
Commd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127385COMM domain-containing protein 3; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B. Modulates Na(+) transport in epithelial cel [...]
Mier2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127387Mesoderm induction early response protein 2; Transcriptional repressor.
Pogk protein networkhttps://string-db.org/network/10090.ENSMUSP00000127395Pogo transposable element with KRAB domain.
Sox21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127396Transcription factor SOX-21; May play a role as an activator of transcription of OPRM1. Overexpression of SOX21 can up-regulate the OPRM1 distal promoter activity in mor-expressing neuronal cells [...]
Fndc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127404Fibronectin type III domain-containing protein 4; Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro- inflammatory gene expressio [...]
Borcs5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127413BLOC-1-related complex subunit 5; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BO [...]
Spert protein networkhttps://string-db.org/network/10090.ENSMUSP00000127439Protein chibby homolog 2; Belongs to the chibby family. SPERT subfamily.
Smim7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127441Small integral membrane protein 7.
2210408I21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000127449Uncharacterized protein KIAA0825 homolog.
Prr22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127457Proline-rich 22.
Vmn2r91 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127465Vomeronasal 2, receptor 91.
Mapk1ip1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000127475MAPK-interacting and spindle-stabilizing protein-like; Belongs to the MISS family.
Tnxb protein networkhttps://string-db.org/network/10090.ENSMUSP00000127487Tenascin XB.
L1td1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127504LINE-1 type transposase domain-containing protein 1; Belongs to the transposase 22 family.
Vmn2r114 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127505Vomeronasal 2, receptor 114.
Vmn2r18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127506Vomeronasal 2, receptor 18.
Gm8897 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127509Predicted gene 8897.
Vmn2r4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127513Vomeronasal 2, receptor 4.
Gm17019 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127520Predicted gene 17019.
Idh3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000127526Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer comp [...]
Trim43a protein networkhttps://string-db.org/network/10090.ENSMUSP00000127527Tripartite motif-containing protein 43A.
Myh15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127539Myosin, heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Rab40c protein networkhttps://string-db.org/network/10090.ENSMUSP00000127546Ras-related protein Rab-40C; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequ [...]
Atp6v0e protein networkhttps://string-db.org/network/10090.ENSMUSP00000127552V-type proton ATPase subunit e 1; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Gm8237 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127555Predicted gene 8237.
Fam163b protein networkhttps://string-db.org/network/10090.ENSMUSP00000127556Protein FAM163B.
Tmem207 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127563Transmembrane protein 207.
Gm3542 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127565Predicted gene 3542.
Guk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127566Guanylate kinase; Catalyzes the phosphorylation of GMP to GDP. Essential enzyme for recycling GMP and indirectly, cyclic GMP (cGMP). Involved in the cGMP metabolism in photoreceptors (By similari [...]
Cdca2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127571Cell division cycle-associated protein 2; Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts [...]
Dennd1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000127580DENN domain-containing protein 1B; Guanine nucleotide exchange factor (GEF) for RAB35 that acts as a regulator of T-cell receptor (TCR) internalization in TH2 cells. Acts by promoting the exchang [...]
Cyfip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127586Cytoplasmic FMR1-interacting protein 2; Part of the WAVE1 complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). Involved in T-cell adhe [...]
2300009A05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000127596Uncharacterized protein C15orf61 homolog.
Zc3h12c protein networkhttps://string-db.org/network/10090.ENSMUSP00000127603Probable ribonuclease ZC3H12C; May function as RNase and regulate the levels of target RNA species.
Itgb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127604Integrin beta-4; Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte po [...]
Aqp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127611Aquaporin-5; Forms a water-specific channel (By similarity). Plays an important role in fluid secretion in salivary glands. Required for TRPV4 activation by hypotonicity. Together with TRPV4, con [...]
H1f7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127616Testis-specific H1 histone; Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Inv [...]
Serpinb6c protein networkhttps://string-db.org/network/10090.ENSMUSP00000127619Serine (or cysteine) peptidase inhibitor, clade B, member 6c; Belongs to the serpin family.
Sept7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127641Septin-7; Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for nor [...]
Arsa protein networkhttps://string-db.org/network/10090.ENSMUSP00000127646Arylsulfatase A; Hydrolyzes cerebroside sulfate. Belongs to the sulfatase family.
Phf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127653Histone lysine demethylase PHF8; Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain developme [...]
Dtwd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127662DTW domain-containing protein 1.
Pih1d3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127665Protein PIH1D3; Plays a role in cytoplasmic pre-assembly of axonemal dynein.
Arid3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000127678AT-rich interactive domain-containing protein 3C.
H2ac6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127684H2A clustered histone 6.
Bscl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127685Seipin; Is a regulator of lipid catabolism essential for adipocyte differentiation. Necessary for correct lipid storage and lipid droplets maintenance; may play a tissue-autonomous role in contro [...]
Tifa protein networkhttps://string-db.org/network/10090.ENSMUSP00000127700TRAF-interacting protein with FHA domain-containing protein A; Adapter molecule that plays a key role in the activation of proinflammatory NF-kappa-B signaling following detection of bacterial pa [...]
Fam3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000127709Protein FAM3C; May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition.
Prr23a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127711Proline-rich 23A, member 1.
Tns1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127715Tensin 1.
Pid1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127716PTB-containing, cubilin and LRP1-interacting protein; Increases proliferation of preadipocytes without affecting adipocytic differentiation.
Zbtb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127746Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation.
Endod1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127751Endonuclease domain-containing 1 protein; May act as a DNase and a RNase; Belongs to the DNA/RNA non-specific endonuclease family.
Gm17542 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127757Predicted gene, 17542.
2610021A01Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000127760RIKEN cDNA 2610021A01 gene.
C130050O18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000127769RIKEN cDNA C130050O18 gene.
Kcne1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000127773Potassium voltage-gated channel subfamily E regulatory beta subunit 5; Potassium channel ancillary subunit that is essential for generation of some native K(+) currents by virtue of formation of [...]
Eif4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000127774Eukaryotic translation initiation factor 4B; Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presen [...]
Ttll6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127778Tubulin polyglutamylase TTLL6; Polyglutamylase which preferentially modifies alpha-tubulin. Mediates tubulin polyglutamylation in cilia. Involved in the side-chain elongation step of the polyglut [...]
Nfat5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127784Nuclear factor of activated T-cells 5; Transcription factor involved in the transcriptional regulation of osmoprotective and inflammatory genes. Regulates hypertonicity-induced cellular accumulat [...]
Nrep protein networkhttps://string-db.org/network/10090.ENSMUSP00000127787Neuronal regeneration-related protein; May have roles in cellular differentiation. Ectopic expression induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. [...]
Shq1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127797Protein SHQ1 homolog; Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthes [...]
Baiap2l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127816Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2; Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to [...]
Gm8068 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127822Predicted gene 8068.
Vmn2r16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127838Vomeronasal 2, receptor 16.
Ap2a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127842AP-2 complex subunit alpha-1; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathw [...]
Pafah1b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127851Platelet-activating factor acetylhydrolase IB subunit beta; Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit; Belongs to the 'GDSL' lipolytic enzyme [...]
Lyrm9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127853LYR motif-containing protein 9; Belongs to the complex I LYR family. LYRM9 subfamily.
Phf11b protein networkhttps://string-db.org/network/10090.ENSMUSP00000127857PHD finger protein 11B.
Rpl9-ps6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127859Ribosomal protein L9, pseudogene 6.
Vmn1r94 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127861Taste receptor type 2.
Cyp11b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127888Cytochrome P450, family 11, subfamily b, polypeptide 1; Belongs to the cytochrome P450 family.
Atp6v1fnb protein networkhttps://string-db.org/network/10090.ENSMUSP00000127891Protein ATP6V1FNB.
Hdlbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000127903Vigilin; Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol (By similarity).
Rimbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127909RIMS-binding protein 3; Component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development. Important for male fe [...]
Mdm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127919Nuclear protein MDM1; Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules. Belongs to the MDM1 family.
Ifna11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127921Interferon alpha-11; Has antiviral and antiproliferative activities. Produced by macrophages and stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase (By si [...]
Inpp5d protein networkhttps://string-db.org/network/10090.ENSMUSP00000127941Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIn [...]
Fam71a protein networkhttps://string-db.org/network/10090.ENSMUSP00000127945Family with sequence similarity 71, member A.
Cfap97d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127953Uncharacterized protein CFAP97D2; Belongs to the CFAP97 family.
Cep55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127961Centrosomal protein of 55 kDa; Plays a role in mitotic exit and cytokinesis. Recruits PDCD6IP and TSG101 to midbody during cytokinesis. Required for successful completion of cytokinesis. Not requ [...]
Gm17555 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127976Predicted gene, 17555.
Vmn2r113 protein networkhttps://string-db.org/network/10090.ENSMUSP00000127981Vomeronasal 2, receptor 113.
Dynlt1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000127990Dynein light chain Tctex-type 1A.
Blm protein networkhttps://string-db.org/network/10090.ENSMUSP00000127995Bloom syndrome protein homolog; ATP-dependent DNA helicase that unwinds single- and double- stranded DNA in a 3'-5' direction. Participates in DNA replication and repair (By similarity). Involved [...]
Sorbs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128000Sorbin and SH3 domain-containing protein 2; Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex w [...]
Vmn1r61 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128012Vomeronasal type-1 receptor.
Vmn2r14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128015Vomeronasal 2, receptor 14.
Sugp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128029SURP and G-patch domain-containing protein 2; May play a role in mRNA splicing.
Cyp2a22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128030Cytochrome P450, family 2, subfamily a, polypeptide 22; Belongs to the cytochrome P450 family.
Gfi1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000128052Zinc finger protein Gfi-1b; Essential proto-oncogenic transcriptional regulator necessary for development and differentiation of erythroid and megakaryocytic lineages. Component of a RCOR-GFI-KDM [...]
Ihh protein networkhttps://string-db.org/network/10090.ENSMUSP00000128056Indian hedgehog protein C-product; Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with s [...]
Kctd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128070BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.
Olfr247 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128078Olfactory receptor 247.
Tgm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128090Protein-glutamine gamma-glutamyltransferase K; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during forma [...]
Fiz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128105Flt3-interacting zinc finger protein 1; May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation (By similarity).
Vmn2r116 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128106Vomeronasal type-2 receptor 116; Receptor for the Esp1 pheromone. Mediates the response to Esp1 which enhances female sexual receptive behavior (lordosis) upon male mounting, resulting in success [...]
Pglyrp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128113Peptidoglycan recognition protein 4; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram- [...]
Pirt protein networkhttps://string-db.org/network/10090.ENSMUSP00000128117Phosphoinositide-interacting protein; Regulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin. Positively regulates TRPV1 channel activity via phosphatidylinositol 4,5-bisph [...]
Pdzk1ip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128118PDZK1-interacting protein 1.
Abca7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128121ATP-binding cassette sub-family A member 7; Probable ATP-binding cassette (ABC) transporter that plays a role in lipid homeostasis and macrophage-mediated phagocytosis. Binds APOA1 and may functi [...]
Pick1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128126PRKCA-binding protein; Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the [...]
Coch protein networkhttps://string-db.org/network/10090.ENSMUSP00000128127Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork.
Fancb protein networkhttps://string-db.org/network/10090.ENSMUSP00000128141Fanconi anemia group B protein homolog; DNA repair protein required for FANCD2 ubiquitination.
Gm8879 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128144Predicted gene 8879.
Jade1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128152Protein Jade-1; Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetyl [...]
Elof1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128173Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family [...]
C2cd4d protein networkhttps://string-db.org/network/10090.ENSMUSP00000128182C2 calcium-dependent domain-containing protein 4D.
Spata31d1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000128200Spermatogenesis-associated 31 subfamily D, member 1D.
Gm44501 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128205Predicted readthrough transcript, 44501.
Acss3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128209Acyl-CoA synthetase short-chain family member 3, mitochondrial; Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids (By similarity). Propionate is the preferred substrate but can a [...]
Gm7954 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128216Predicted gene 17027.
Dtwd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128219DTW domain-containing protein 2.
Slc37a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128223Glucose-6-phosphate exchanger SLC37A1; Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and transl [...]
Atp13a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128224Probable cation-transporting ATPase 13A3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
Slc39a8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128245Zinc transporter ZIP8; Acts as a manganese and zinc influx transporter. Plays a role in manganese reabsorption in the proximal tubule of the kidney and in manganese uptake into the brain.
Tbx22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128247T-box transcription factor TBX22; Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis.
Slc39a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128256Zinc transporter ZIP3; Acts as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family.
Tfdp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128260Transcription factor Dp-2; Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter reg [...]
Muc5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000128276Mucin 5, subtype B, tracheobronchial.
Iqgap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128278Ras GTPase-activating-like protein IQGAP1; Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activ [...]
Rtl9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128287Retrotransposon Gag-like protein 9.
Pum2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128292Pumilio homolog 2; Sequence-specific RNA-binding protein that acts as a post- transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Resp [...]
Thbs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128308Thrombospondin-2; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions. Ligand for CD36 mediating antiangiogenic properties.
Ppfia4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128314Liprin-alpha 4.
Igfbp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128318Insulin-like growth factor-binding protein 7; Binds IGF-I and IGF-II with a relatively low affinity Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion (By similarity).
Mfsd4b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128324Sodium-dependent glucose transporter 1A; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney. Belongs to the major facilitator super [...]
Cers1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128325Embryonic growth/differentiation factor 1; May mediate cell differentiation events during embryonic development.
Nolc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128331Nucleolar and coiled-body phosphoprotein 1; Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and mod [...]
Vmn2r15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128333Vomeronasal 2, receptor 15.
Vmn2r100 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128350Vomeronasal 2, receptor 100.
Ost4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128352Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Ma [...]
G3bp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128353Ras GTPase-activating protein-binding protein 2; Scaffold protein that plays an essential role in cytoplasmic stress granule formation which acts as a platform for antiviral signaling.
Olfr180 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128358Olfactory receptor Olfr180; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Gm17027 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128369Predicted gene 17027.
Atp23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128382Mitochondrial inner membrane protease ATP23 homolog.
Hectd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128387Probable E3 ubiquitin-protein ligase HECTD2; Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly tran [...]
Pdgfd protein networkhttps://string-db.org/network/10090.ENSMUSP00000128388Platelet-derived growth factor D, receptor-binding form; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and ch [...]
Snrpe protein networkhttps://string-db.org/network/10090.ENSMUSP00000128400Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, [...]
Tap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128401Antigen peptide transporter 1; Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold [...]
Iltifb protein networkhttps://string-db.org/network/10090.ENSMUSP00000128415Interleukin-22b; Cytokine that contributes to the inflammatory response in vivo; Belongs to the IL-10 family.
Ddx6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128421Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, plays a role in mRNA decapping (By similarity). Blocks autophagy in nutrient-rich conditions by repressing the expres [...]
Atp8b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128423Phospholipid-transporting ATPase ID; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the [...]
Gm8871 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128435Predicted pseudogene 8871.
Ap3m2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128446AP-3 complex subunit mu-2; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplas [...]
Mast4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128464Microtubule-associated serine/threonine-protein kinase 4.
Clnk protein networkhttps://string-db.org/network/10090.ENSMUSP00000128473Cytokine-dependent hematopoietic cell linker; An adapter protein which plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B-cell antigen receptor (BCR) signa [...]
Anp32e protein networkhttps://string-db.org/network/10090.ENSMUSP00000128483Acidic leucine-rich nuclear phosphoprotein 32 family member E; Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 [...]
Gm6133 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128489Predicted gene 6133; Belongs to the universal ribosomal protein uL22 family.
Ppp1r15a protein networkhttps://string-db.org/network/10090.ENSMUSP00000128497Protein phosphatase 1 regulatory subunit 15A; Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut- [...]
Daxx protein networkhttps://string-db.org/network/10090.ENSMUSP00000128504Death domain-associated protein 6; Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcripti [...]
Trim13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128509E3 ubiquitin-protein ligase TRIM13; Endoplasmic reticulum (ER) membrane anchored E3 ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a [...]
Unc5d protein networkhttps://string-db.org/network/10090.ENSMUSP00000128521Netrin receptor UNC5D; Receptor for the netrin NTN4 that promotes neuronal cell survival. Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration (By [...]
Rnf20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128546E3 ubiquitin-protein ligase BRE1A; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a spec [...]
Evi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128569Protein EVI2B; Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor [...]
Nbeal2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128586Neurobeachin-like protein 2; Probably involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogen [...]
Gm10376 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128599Predicted gene 10376.
Armh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128613Armadillo-like helical domain-containing 1.
Mcmdc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128620Minichromosome maintenance domain-containing protein 2; Plays an important role in meiotic recombination and associated DNA double-strand break repair.
Gdf10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128621Growth/differentiation factor 10; Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway. Plays an inhi [...]
Gm8906 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128633Predicted gene 8906.
Nabp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128634SOSS complex subunit B1; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as [...]
Rab12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128645Ras-related protein Rab-12; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle bet [...]
Lbhd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128648LBH domain-containing 2.
Fbxw25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128652F-box and WD-40 domain protein 25.
Zfp667 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128658Zinc finger protein 667; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Odc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128661Ornithine decarboxylase; Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and sp [...]
Mmgt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128669Membrane magnesium transporter 2; Mediates Mg(2+) transport; Belongs to the membrane magnesium transporter (TC 1.A.67) family.
Megf11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128672Multiple epidermal growth factor-like domains protein 11; May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a m [...]
Naalad2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128674N-acetylated-alpha-linked acidic dipeptidase 2; Has N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Also exhibits a dipeptidyl-peptidase IV type activity. Inactivates the pepti [...]
Cndp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128696Cytosolic non-specific dipeptidase; Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Catalyzes the production of N- lactoyl-amino acids from lacta [...]
5031439G07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000128699Uncharacterized protein KIAA0930 homolog.
Tmem176b protein networkhttps://string-db.org/network/10090.ENSMUSP00000128705Transmembrane protein 176B; May play a role in the process of maturation of dendritic cells (By similarity). Required for the development of cerebellar granule cells.
Taf5l protein networkhttps://string-db.org/network/10090.ENSMUSP00000128710TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating hi [...]
Col9a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128718Collagen, type IX, alpha 3.
Gm8257 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128723Predicted pseudogene 8257.
Rbak protein networkhttps://string-db.org/network/10090.ENSMUSP00000128731RB-associated KRAB zinc finger protein; May repress E2F-dependent transcription. May promote AR- dependent transcription.
Spaca6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128732Sperm acrosome membrane-associated protein 6; Sperm protein potentially involved sperm-egg fusion.
Ccdc141 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128736Coiled-coil domain-containing 141.
Gm8138 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128755Predicted gene 8138.
Zfp703 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128757Zinc finger protein 703; Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates ce [...]
Kdm3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000128789Lysine-specific demethylase 3A; Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dim [...]
Vmn2r85 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128792Vomeronasal 2, receptor 85.
Jrkl protein networkhttps://string-db.org/network/10090.ENSMUSP00000128798Jerky protein homolog-like.
Myl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128803Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium.
Gm21992 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128810Predicted gene 21992.
Ubap1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000128815Ubiquitin-associated protein 1-like.
Nup155 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128819Nuclear pore complex protein Nup155; Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins [...]
Susd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128826Sushi domain-containing 5.
Cdkn1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000128828Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cy [...]
Utf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128848Undifferentiated embryonic cell transcription factor 1; Acts as a transcriptional coactivator of ATF2.
Rad51ap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128854RAD51-associated protein 2.
Csnk1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128871Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of pro [...]
Dlec1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128874Deleted in lung and esophageal cancer protein 1 homolog; May act as a tumor suppressor by inhibiting cell proliferation.
Aadacl2fm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128877AADACL2 family member 2.
Whamm protein networkhttps://string-db.org/network/10090.ENSMUSP00000128881WASP homolog-associated protein with actin, membranes and microtubules; Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatu [...]
Tpx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128888Targeting protein for Xklp2; Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or [...]
Fbll1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128889rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA pro [...]
Dlk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128897Protein delta homolog 2; Regulates adipogenesis.
Os9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128914Protein OS-9; Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as imprope [...]
Mrpl16 protein networkhttps://string-db.org/network/10090.ENSMUSP0000012891539S ribosomal protein L16, mitochondrial; Belongs to the universal ribosomal protein uL16 family.
Arpp19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128921cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically [...]
Ttpal protein networkhttps://string-db.org/network/10090.ENSMUSP00000128922Alpha-tocopherol transfer protein-like; May act as a protein that binds a hydrophobic ligand.
Enpp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128941Ectonucleotide pyrophosphatase/phosphodiesterase family member 2; Hydrolyzes lysophospholipids to produce the signaling molecule lysophosphatidic acid (LPA) in extracellular fluids. Major substra [...]
Prg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128943Proteoglycan 4 C-terminal part; Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent s [...]
Zfp655 protein networkhttps://string-db.org/network/10090.ENSMUSP00000128969Zinc finger protein 655.
Nfatc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129001Nuclear factor of activated T-cells, cytoplasmic 1; Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also [...]
Lamtor5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129012Ragulator complex protein LAMTOR5; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth [...]
Tdrd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129019Tudor domain-containing protein 3; Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmet [...]
Sept10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129023Septin-10; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin [...]
Mapk6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129024Mitogen-activated protein kinase 6; Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still uncle [...]
Cd79b protein networkhttps://string-db.org/network/10090.ENSMUSP00000129029B-cell antigen receptor complex-associated protein beta chain; Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor comple [...]
Dmkn protein networkhttps://string-db.org/network/10090.ENSMUSP00000129031Dermokine; May act as a soluble regulator of keratinocyte differentiation.
Gm8082 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129043Predicted gene 3015.
Gm17026 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129050Predicted gene 17026.
Gpr62 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129055G-protein coupled receptor 62; Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for [...]
Kctd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129059BTB/POZ domain-containing protein KCTD6; Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal d [...]
Rpl26 protein networkhttps://string-db.org/network/10090.ENSMUSP0000012907260S ribosomal protein L26; Component of the large ribosomal subunit.
Vmn2r63 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129089Vomeronasal 2, receptor 63.
Oplah protein networkhttps://string-db.org/network/10090.ENSMUSP000001291005-oxoprolinase; Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
Sis protein networkhttps://string-db.org/network/10090.ENSMUSP00000129116Sucrase isomaltase (alpha-glucosidase).
Gm9611 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129118Predicted gene 9611.
Acot7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129121Cytosolic acyl coenzyme A thioester hydrolase; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the [...]
Zfp454 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129125Zinc finger protein 454.
Vmn2r20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129145Vomeronasal 2, receptor 20.
Tns2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129146Tensin-2; Tyrosine-protein phosphatase which regulates cell motility proliferation and muscle-response to insulin. In muscles and under catabolic conditions, dephosphorylates IRS1 leading to its [...]
Gm8005 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129153Predicted gene 8005.
Zfp511 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129154Zinc finger protein 511; May be involved in transcriptional regulation.
Tcea1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129157Transcription elongation factor A protein 1; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property [...]
Rab11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000129163Ras-related protein Rab-11A; The small GTPases Rab areR key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle b [...]
A530084C06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000129167RIKEN cDNA A530084C06 gene.
Abhd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129169Monoacylglycerol lipase ABHD6; Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regu [...]
Ankrd65 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129173Ankyrin repeat domain 65.
Pfdn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129178Prefoldin subunit 5; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which the [...]
Insyn2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000129183INSYN2B protein; Belongs to the INSYN2 family.
Tomm70a protein networkhttps://string-db.org/network/10090.ENSMUSP00000129186Mitochondrial import receptor subunit TOM70; Receptor that accelerates the import of all mitochondrial precursor proteins.
Tbck protein networkhttps://string-db.org/network/10090.ENSMUSP00000129205TBC domain-containing protein kinase-like protein; Involved in the modulation of mTOR signaling and expression of mTOR complex components. Involved in the regulation of cell proliferation and gro [...]
Vmn2r87 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129215Vomeronasal 2, receptor 87.
Agbl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129216Cytosolic carboxypeptidase 2; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational [...]
Myo9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000129220Unconventional myosin-IXb; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absenc [...]
Insyn2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000129222Inhibitory synaptic factor 2A; Component of the protein machinery at the inhibitory synapses, probably acting as a scaffold. Inhibitory synapses dampen neuronal activity through postsynaptic hype [...]
Synj2bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000129224Synaptojanin-2-binding protein; Isoform 1 regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced s [...]
Alx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129230ALX homeobox protein 1; Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Mo [...]
Pkdcc protein networkhttps://string-db.org/network/10090.ENSMUSP00000129238Extracellular tyrosine-protein kinase PKDCC; Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is es [...]
Slc15a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129239Solute carrier family 15 member 5; Proton oligopeptide cotransporter.
Trim43c protein networkhttps://string-db.org/network/10090.ENSMUSP00000129255Tripartite motif-containing protein 43C.
Cyp4f15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129264Cytochrome P450, family 4, subfamily f, polypeptide 15; Belongs to the cytochrome P450 family.
Olfr287 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129271Olfactory receptor.
Tldc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129278TLD domain-containing protein 2; Belongs to the OXR1 family.
Drosha protein networkhttps://string-db.org/network/10090.ENSMUSP00000129279Ribonuclease 3; Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex th [...]
Hcar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129280Hydroxycarboxylic acid receptor 1; Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway.
Krtap27-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129289Keratin-associated protein 27-1.
Vmn2r120 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129296Vomeronasal 2, receptor 120.
Clp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129300Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double-stranded DNA (d [...]
Pex2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129311Peroxisome biogenesis factor 2; Somewhat implicated in the biogenesis of peroxisomes; Belongs to the pex2/pex10/pex12 family.
Vmn2r97 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129313Vomeronasal 2, receptor 97.
Mtfr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129315Mitochondrial fission regulator 2; May play a role in mitochondrial aerobic respiration essentially in the testis. Can also promote mitochondrial fission.
Rpl3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000129325Ribosomal protein L3-like; Belongs to the universal ribosomal protein uL3 family.
Scgb1b20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129326Secretoglobin, family 1B, member 20.
Vmn2r110 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129347Vomeronasal 2, receptor 110.
Nemp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129351Nuclear envelope integral membrane protein 2; Belongs to the NEMP family.
Gm16506 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129358Predicted gene 16506.
Klf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129363Krueppel-like factor 3; Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis; Belongs to the krueppel C2H2-type zinc-finger protein family.
Med16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129375Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. M [...]
Olfr564 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129376Olfactory receptor.
Pnldc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129377Poly(A)-specific ribonuclease PNLDC1; 3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) t [...]
Csrp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129378Cysteine and glycine-rich protein 3; Positive regulator of myogenesis. Acts as cofactor for myogenic bHLH transcription factors such as MYOD1, and probably MYOG and MYF6. Enhances the DNA-binding [...]
Slc6a17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129379Sodium-dependent neutral amino acid transporter SLC6A17; Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of [...]
Txk protein networkhttps://string-db.org/network/10090.ENSMUSP00000129397Tyrosine-protein kinase TXK; Non-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. Regulates the development, function and differentiati [...]
Bean1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129403Protein BEAN1.
Pate11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129404Secreted TFP/Ly-6/uPAR protein PATE-P.
Eid1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129413EP300-interacting inhibitor of differentiation 1; Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be [...]
Cd276 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129418CD276 antigen; Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in [...]
Diaph3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129420Protein diaphanous homolog 3; Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers. Required for cytokinesis, stress fibe [...]
Vmn1r252 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129429Taste receptor type 2.
Aadacl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129444Arylacetamide deacetylase-like 2.
Rbm20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129447RNA-binding protein 20; RNA-binding protein that acts as a regulator of mRNA splicing of a subset of genes involved in cardiac development. Regulates splicing of TTN (Titin).
Vmn1r260 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129454Vomeronasal 1 receptor 260.
Cables1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129463CDK5 and ABL1 enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin- dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by acti [...]
Vmn2r45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129466Vomeronasal 2, receptor 45.
Otogl protein networkhttps://string-db.org/network/10090.ENSMUSP00000129467Otogelin-like protein.
Rabggtb protein networkhttps://string-db.org/network/10090.ENSMUSP00000129481Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -X [...]
Tent5d protein networkhttps://string-db.org/network/10090.ENSMUSP00000129483Terminal nucleotidyltransferase 5D.
Zfp111 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129484Zinc finger protein ZFP111.
Mnx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129503Motor neuron and pancreas homeobox protein 1; Putative transcription factor involved in pancreas development and function.
Insc protein networkhttps://string-db.org/network/10090.ENSMUSP00000129505Protein inscuteable homolog; May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis. May regulate cell proliferation and di [...]
Card10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129513Caspase recruitment domain-containing protein 10; Activates NF-kappa-B via BCL10 and IKK.
Vmn2r9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129520Vomeronasal 2, receptor 9.
Gm3252 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129533Predicted gene 3252.
Vmn2r77 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129540Vomeronasal 2, receptor 77.
1500009L16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000129542Overexpressed in colon carcinoma 1 protein homolog; Belongs to the OCC1 family.
Myh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129544Myosin, heavy polypeptide 2, skeletal muscle, adult; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Pate7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129553Prostate and testis-expressed 7.
Nynrin protein networkhttps://string-db.org/network/10090.ENSMUSP00000129557Protein NYNRIN.
Rasl2-9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129559GTP-binding nuclear protein Ran, testis-specific isoform; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. [...]
Gstp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129565Glutathione S-transferase P 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Can metabolize 1- chloro-2,4-dinitrobenzene. Regulates ne [...]
Vmn2r56 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129566Vomeronasal 2, receptor 56.
Dpy19l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129575Probable C-mannosyltransferase DPY19L1; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.
Vmn2r61 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129576Vomeronasal 2, receptor 61.
Ccdc71l protein networkhttps://string-db.org/network/10090.ENSMUSP00000129581Coiled-coil domain-containing 71-like.
Bcar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129584Breast cancer anti-estrogen resistance protein 1; Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of [...]
Cuedc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129589CUE domain-containing protein 2; Controls PGR and ESR1 protein levels through their targeting for ubiquitination and subsequent proteasomal degradation. Belongs to the CUEDC2 family.
Tceal8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129591Transcription elongation factor A protein-like 8; May be involved in transcriptional regulation; Belongs to the TFS-II family. TFA subfamily.
Ptprj protein networkhttps://string-db.org/network/10090.ENSMUSP00000129592Receptor-type tyrosine-protein phosphatase eta; Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, RET, KDR, LYN, SRC, MAPK1, MAPK3, [...]
Tonsl protein networkhttps://string-db.org/network/10090.ENSMUSP00000129597Tonsoku-like protein; Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is re [...]
Trnp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129613TMF-regulated nuclear protein 1; DNA-binding factor that regulates the expression of a subset of genes and plays a key role in tangential, radial, and lateral expansion of the brain neocortex. Re [...]
Erh protein networkhttps://string-db.org/network/10090.ENSMUSP00000129620Enhancer of rudimentary homolog; May have a role in the cell cycle; Belongs to the E(R) family.
Tdrkh protein networkhttps://string-db.org/network/10090.ENSMUSP00000129635Tudor and KH domain-containing protein; Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization [...]
Ppp4r3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000129654Serine/threonine-protein phosphatase 4 regulatory subunit 3A; Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizin [...]
Gm884 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129662Predicted gene 884.
Prc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129675Protein regulator of cytokinesis 1; Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formatio [...]
Nrxn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129678Neurexin-3; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling (By similarity).
Igfn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129680Immunoglobulin-like and fibronectin type III domain-containing protein 1.
Sftpa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129696Pulmonary surfactant-associated protein A; In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air- liquid interface in the alveo [...]
Enoph1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129704Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1 [...]
Ghitm protein networkhttps://string-db.org/network/10090.ENSMUSP00000129712Growth hormone-inducible transmembrane protein; Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c (By similarity).
Gm44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129722Predicted gene 44.
Nup37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129728Nucleoporin Nup37; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex [...]
Dnaja1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129730DnaJ homolog subfamily A member 1; Co-chaperone for HSPA8/Hsc70. Plays a role in protein transport into mitochondria via its role as co-chaperone. Stimulates ATP hydrolysis, but not the folding o [...]
Cenpf protein networkhttps://string-db.org/network/10090.ENSMUSP00000129738Centromere protein F.
Eps15l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129739Epidermal growth factor receptor substrate 15-like 1; Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of i [...]
Vmn2r105 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129762Vomeronasal 2, receptor 105.
Parp10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129765Protein mono-ADP-ribosyltransferase PARP10; ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate and aspartate residues on target proteins. In contrast to PARP1 and PARP2, it i [...]
Psma2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129767Proteasome subunit alpha type-2; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles w [...]
Gm6482 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129770Predicted gene 6482.
Dis3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000129772DIS3-like exonuclease 1; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA proce [...]
Akap13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129784A-kinase anchor protein 13; Scaffold protein that plays an important role in assembling signaling complexes downstream of several types of G protein-coupled receptors. Activates RHOA in response [...]
Pym1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129789Partner of Y14 and mago; Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon- exon junction on mRNAs and serves as a position [...]
Vmn1r238 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129804Vomeronasal type-1 receptor.
Klhl33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129810Kelch-like 33.
Atp10a protein networkhttps://string-db.org/network/10090.ENSMUSP00000129811Probable phospholipid-transporting ATPase VA; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the out [...]
Gm3164 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129814Predicted gene 3164.
Tarbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129815TAR RNA-binding protein 1.
Vmn1r101 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129819Vomeronasal type-1 receptor.
Gm50241 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129823Decreased expression in renal and prostate cancer protein; Potential tumor suppressor; Belongs to the DERPC family.
Farsb protein networkhttps://string-db.org/network/10090.ENSMUSP00000129828Phenylalanine--tRNA ligase beta subunit.
Ripk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129831Receptor-interacting serine/threonine-protein kinase 1; Serine-threonine kinase which is a key regulator of both cell death and cell survival. Exhibits kinase activity- dependent functions that t [...]
Heatr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129832HEAT repeat-containing 4.
Caps2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129887Calcyphosin-2.
Vmn2r104 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129895Vomeronasal 2, receptor 104.
Gm6401 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129907Predicted gene 6401.
Gm3233 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129915Predicted gene 3233.
Tfap2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000129922Transcription factor AP-2 gamma; Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors [...]
H4c14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129930H4 clustered histone 14.
Esp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129933Exocrine gland secreted peptide 8.
Krtap11-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129948Keratin-associated protein 11-1.
C5ar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129972C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity si [...]
Ctif protein networkhttps://string-db.org/network/10090.ENSMUSP00000129974CBP80/20-dependent translation initiation factor; Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex (CBC), that takes place during or right after [...]
Mrgpra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000129978Mas-related G-protein coupled receptor member A1; Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with [...]
Zfp236 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130004Zinc finger protein 236.
Cyp27b1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000013000525-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; A cytochrome P450 monooxygenase involved in vitamin D metabolism and in calcium and phosphorus homeostasis. Catalyzes the rate-limiting ste [...]
Gm3238 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130008Predicted gene 3238.
Fan1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130012Fanconi-associated nuclease 1; Nuclease required for the repair of DNA interstrand cross- links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair [...]
Hnrnpf protein networkhttps://string-db.org/network/10090.ENSMUSP00000130023Heterogeneous nuclear ribonucleoprotein F, N-terminally processed; Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events [...]
Slitrk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130057SLIT and NTRK-like protein 2; It is involved in synaptogenesis. Promotes excitatory synapse differentiation (By similarity). Suppresses neurite outgrowth.
Nat2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130065Arylamine N-acetyltransferase 2; Participates in the detoxification of a plethora of hydrazine and arylamine drugs. 2-aminofluorene and p-aminobenzoic acid (PABA) are preferred substrates for NAT [...]
Cyp39a1 protein networkhttps://string-db.org/network/10090.ENSMUSP0000013007324-hydroxycholesterol 7-alpha-hydroxylase; A cytochrome P450 monooxygenase involved in neural cholesterol clearance through bile acid synthesis. Catalyzes 7-alpha hydroxylation of (24S)-hydroxych [...]
Comt protein networkhttps://string-db.org/network/10090.ENSMUSP00000130077Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certa [...]
Gm2974 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130084Predicted gene 2974.
1700092M07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000130094Testis-expressed protein 54.
Vmn2r82 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130114Vomeronasal 2, receptor 82.
Smad2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130115Mothers against decapentaplegic homolog 2; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth fac [...]
Snx14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130116Sorting nexin-14; Plays a role in maintaining normal neuronal excitability and synaptic transmission. May be involved in several stages of intracellular trafficking. Required for autophagosome cl [...]
D630045J12Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000130121UPF0606 protein KIAA1549; Belongs to the UPF0606 family.
Gnb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130123Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling sys [...]
Mybpc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130127Myosin-binding protein C, fast-type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F- actin and native thin fil [...]
Gm17364 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130129Predicted gene, 17364.
Phc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130142Polyhomeotic-like protein 3; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, includi [...]
Fubp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130145Far upstream element-binding protein 1; Regulates MYC expression by binding to a single-stranded far- upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor [...]
Prr5l protein networkhttps://string-db.org/network/10090.ENSMUSP00000130152Proline-rich protein 5-like; Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton (By similarity). Regulates the activity o [...]
Gm7945 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130156Predicted gene 7945.
Gm10340 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130159Predicted gene 10340.
Arid3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000130173AT-rich interactive domain-containing protein 3B; Transcription factor involved in the production of cranial mesenchymal tissues. Favors nuclear targeting of ARID3A.
Zfp385a protein networkhttps://string-db.org/network/10090.ENSMUSP00000130176Zinc finger protein 385A; RNA-binding protein that affects the localization and the translation of a subset of mRNA. May play a role in adipogenesis through binding to the 3'-UTR of CEBPA mRNA an [...]
Kcnmb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130177Potassium large conductance calcium-activated channel, subfamily M, beta member 3.
Slc3a2 protein networkhttps://string-db.org/network/10090.ENSMUSP000001301944F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer. The h [...]
St13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130195Hsc70-interacting protein; One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that h [...]
Clasp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130201CLIP-associating protein 2; Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating fr [...]
Jakmip3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130207Janus kinase and microtubule-interacting protein 3; Belongs to the JAKMIP family.
Gm7138 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130212Predicted gene 7138.
Sin3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000130221Paired amphipathic helix protein Sin3a; Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Als [...]
Qrfprl protein networkhttps://string-db.org/network/10090.ENSMUSP00000130225Pyroglutamylated RFamide peptide receptor-like; Belongs to the G-protein coupled receptor 1 family.
Stra6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130232Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell m [...]
Fxyd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130245FXYD domain-containing ion transport regulator 3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into [...]
Krcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130252Lysine-rich coiled-coil protein 1.
Cmip protein networkhttps://string-db.org/network/10090.ENSMUSP00000130264C-Maf-inducing protein; Plays a role in T-cell signaling pathway.
1600014C10Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000130271Protein C19orf12 homolog.
Vmn1r163 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130288Taste receptor type 2.
Rpp40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130290Ribonuclease P protein subunit p40; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclea [...]
Ctbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130294C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Isoform 2 probably acts as a scaffold for specialized synapses (By similarity). Functions in brown adipose ti [...]
Gm6676 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130300Predicted gene 6676.
Spata2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000130306Spermatogenesis-associated protein 2-like protein.
Cphx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130311Cytoplasmic polyadenylated homeobox 1.
Ssb protein networkhttps://string-db.org/network/10090.ENSMUSP00000130313Lupus La protein homolog; Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
Cyp2d11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130338Cytochrome P450 2D11; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a va [...]
Vmn1r241 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130340Vomeronasal 1 receptor 241.
Trim67 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130343Tripartite motif-containing protein 67.
Arhgap40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130349Rho GTPase-activating protein 40; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Aph1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000130359Putative gamma-secretase subunit APH-1C; Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch rec [...]
Chid1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130360Chitinase domain-containing protein 1; Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length o [...]
Vmn2r108 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130373Vomeronasal 2, receptor 108.
Slc38a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130414Sodium-coupled neutral amino acid transporter 3; Sodium-dependent amino acid/proton antiporter. Mediates electrogenic cotransport of glutamine and sodium ions in exchange for protons. Also recogn [...]
Lingo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130423Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2.
Ddx11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130440ATP-dependent DNA helicase DDX11; DNA-dependent ATPase and ATP-dependent DNA helicase that participates in various functions in genomic stability, including DNA replication, DNA repair and hetero [...]
Tmem238 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130452Transmembrane protein 238.
Gm2663 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130465Predicted gene 2663; Belongs to the peptidase S1 family.
Pate1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130484Prostate and testis-expressed 1.
Sult2a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130490Sulfotransferase; Belongs to the sulfotransferase 1 family.
Cntln protein networkhttps://string-db.org/network/10090.ENSMUSP00000130491Centlein; Required for centrosome cohesion and recruitment of CEP68 to centrosomes.
Gcnt4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130496Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4; Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis. [...]
Mc5r protein networkhttps://string-db.org/network/10090.ENSMUSP00000130497Melanocortin receptor 5; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible m [...]
Tmem255b protein networkhttps://string-db.org/network/10090.ENSMUSP00000130504Transmembrane protein 255B.
S100a7l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130512S100 calcium-binding protein A7-like 2; Belongs to the S-100 family.
Cd200 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130518OX-2 membrane glycoprotein; Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues (By similarity).
Xpo6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130527Exportin-6; Mediates the nuclear export of actin and profilin-actin complexes in somatic cells; Belongs to the exportin family.
Adcy4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130530Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Ndufaf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130532NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; Acts as a molecular chaperone for mitochondrial complex I assembly. Complex I functions in the transfer of electrons from NAD [...]
Suds3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130535Sin3 histone deacetylase corepressor complex component SDS3; Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumo [...]
Hspb9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130551Heat shock protein beta-9.
Arhgef37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130560Rho guanine nucleotide exchange factor 37; May act as a guanine nucleotide exchange factor (GEF).
Ralgps2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130581Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the s [...]
Gm3558 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130601Predicted gene, ENSMUSG00000063277.
Plce1 protein networkhttps://string-db.org/network/10090.ENSMUSP000001306041-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by ac [...]
Vmn2r48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130631Vomeronasal 2, receptor 48.
Ranbp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130636Ran-binding protein 9; May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways. Acts as a mediator of cell spreading and actin cyto [...]
Gba protein networkhttps://string-db.org/network/10090.ENSMUSP00000130660Lysosomal acid glucosylceramidase; Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a [...]
Gm10406 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130661Predicted gene 10406.
Mars protein networkhttps://string-db.org/network/10090.ENSMUSP00000130666Methionine--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and [...]
Ncam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130668Neural cell adhesion molecule 1; This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
Zfyve27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130684Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport (By similarity). Promotes axonal elongation and contributes to the [...]
Rnf43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130685E3 ubiquitin-protein ligase RNF43; E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradati [...]
Ccne2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130693G1/S-specific cyclin-E2; Essential for the control of the cell cycle at the late G1 and early S phase.
Myo18a protein networkhttps://string-db.org/network/10090.ENSMUSP00000130696Unconventional myosin-XVIIIa; May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi memb [...]
Gm17359 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130702Predicted gene, 17359.
Lrch3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130708DISP complex protein LRCH3; As part of the DISP complex, may regulate the association of septins with actin and thereby regulate the actin cytoskeleton.
Tjap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130710Tight junction-associated protein 1.
AU015836 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130711Expressed sequence AU015836.
Gm1979 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130718Predicted gene 1979.
Mrpl13 protein networkhttps://string-db.org/network/10090.ENSMUSP0000013072239S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.
Grm6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130728Metabotropic glutamate receptor 6; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G protein [...]
Olfr860 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130735Olfactory receptor.
Cul3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130738Cullin-3; Core component of multiple cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target [...]
Rbfox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130739RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulate [...]
Gm17654 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130744Predicted gene, 17654.
Slco1a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130746Solute carrier organic anion transporter family member 1A4; Mediates the Na(+)-independent transport of organic anions such as taurocholate, cholate, 17-beta-glucuronosyl estradiol, estrone- 3-su [...]
Luzp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130758Leucine zipper protein 1.
Traf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130759TNF receptor-associated factor 1; Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by T [...]
Gm3468 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130760Predicted gene 3468.
Rhbg protein networkhttps://string-db.org/network/10090.ENSMUSP00000130767Ammonium transporter Rh type B; Functions as a specific ammonium transporter. Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
Prlh protein networkhttps://string-db.org/network/10090.ENSMUSP00000130768Prolactin-releasing hormone.
Oard1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130802ADP-ribose glycohydrolase OARD1; ADP-ribose glycohydrolase that hydrolyzes ADP-ribose and acts on different substrates, such as proteins ADP-ribosylated on glutamate and O-acetyl-ADP-D-ribose. Sp [...]
Lamtor3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130811Ragulator complex protein LAMTOR3; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth [...]
Spata31d1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000130813Spermatogenesis-associated 31 subfamily D, member 1B.
Gm8212 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130823Predicted gene 8212.
Siah3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130827E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 u [...]
B3gnt9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130840UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9.
Olfr1036 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130843Olfactory receptor.
Cdh18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130851Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins.
1700113H08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000130852RIKEN cDNA 1700113H08 gene.
Tpi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130858Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3 [...]
Ino80d protein networkhttps://string-db.org/network/10090.ENSMUSP00000130864INO80 complex subunit D; Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; Belongs [...]
Chrm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130874Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modu [...]
Islr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130879Immunoglobulin superfamily containing leucine-rich repeat protein 2; Required for axon extension during neural development.
Klhdc7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000130884Kelch domain-containing 7B.
Pwwp2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000130888PWWP domain-containing 2B.
Nt5c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130898Cytosolic purine 5'-nucleotidase; May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Pre [...]
Mms19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130900MMS19 nucleotide excision repair protein homolog; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur [...]
Gm8232 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130920Predicted gene 8232.
Dhrs7c protein networkhttps://string-db.org/network/10090.ENSMUSP00000130924Dehydrogenase/reductase SDR family member 7C; Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Dvl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130925Segment polarity protein dishevelled homolog DVL-3; Involved in the signal transduction pathway mediated by multiple Wnt genes; Belongs to the DSH family.
Nrg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130929Pro-neuregulin-4, membrane-bound isoform; Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine p [...]
Tgif1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130930Homeobox protein TGIF1; Binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII-RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR [...]
Fcrl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130936Fc receptor-like protein 1; May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation (By similarity).
Mmut protein networkhttps://string-db.org/network/10090.ENSMUSP00000130941Methylmalonyl-CoA mutase, mitochondrial; Involved in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle; Belongs to th [...]
Otog protein networkhttps://string-db.org/network/10090.ENSMUSP00000130949Otogelin; Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule [...]
Nol4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130950Nucleolar protein 4.
Smim13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130956Small integral membrane protein 13.
Cnfn protein networkhttps://string-db.org/network/10090.ENSMUSP00000130957Cornifelin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
Prepl protein networkhttps://string-db.org/network/10090.ENSMUSP00000130967Prolyl endopeptidase-like; Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue (By similarity). Regulates trans-Golgi [...]
Gpr137 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130969Integral membrane protein GPR137; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. May play a role in autophagy.
Serpina3m protein networkhttps://string-db.org/network/10090.ENSMUSP00000130979Serine protease inhibitor A3M; Belongs to the serpin family.
Gm3327 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130980Predicted gene 3327.
Hlcs protein networkhttps://string-db.org/network/10090.ENSMUSP00000130981Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase; Biotin--protein ligase catalyzing the biotinylation of the 4 biotin-dependent carboxylases acetyl-CoA-carboxylase, pyruvate carboxyla [...]
Lrrc4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000130984Leucine-rich repeat-containing protein 4C; May promote neurite outgrowth of developing thalamic neurons.
Gm9573 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130987Predicted gene 9573.
Gpd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000130992Glycerol-3-phosphate dehydrogenase, mitochondrial.
Lce3d protein networkhttps://string-db.org/network/10090.ENSMUSP00000130993Late cornified envelope 3D.
Cby3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131004Protein chibby homolog 3.
Vsx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131009Visual system homeobox 2; Acts as a transcriptional regulator through binding to DNA at the consensus sequence 5'-[TC]TAATT[AG][AG]-3' upstream of gene promoters. Plays a significant role in the [...]
Sphk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131010Sphingosine kinase 1; Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sph [...]
Keap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131029Kelch-like ECH-associated protein 1; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for u [...]
Sipa1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131030Signal-induced proliferation-associated 1-like protein 1; Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F-actin. Contributes to t [...]
Vmn1r242 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131047Vomeronasal 1 receptor 242.
Cyp4f16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131058Cytochrome P450, family 4, subfamily f, polypeptide 16; Belongs to the cytochrome P450 family.
Sept12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131062Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
Pcdh10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131073Protocadherin 10.
4930433I11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000131120RIKEN cDNA 4930433I11 gene.
Lax1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131126Lymphocyte transmembrane adapter 1; Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
Tmem191c protein networkhttps://string-db.org/network/10090.ENSMUSP00000131127Transmembrane protein 191C; Belongs to the TMEM191 family.
Vmn2r118 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131128Vomeronasal 2, receptor 118.
Akain1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131134A-kinase anchor protein inhibitor 1; Protein kinase A (PKA)-binding protein. Binds to type II regulatory subunits of protein kinase A (PKA) and may block the A- kinase anchoring protein (AKAP)-me [...]
Gm6465 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131137Predicted gene 6465.
C2cd4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000131138Family with sequence similarity 148, member B.
Tmem170b protein networkhttps://string-db.org/network/10090.ENSMUSP00000131144Transmembrane protein 170B; Belongs to the TMEM170 family.
Hbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131158HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferent [...]
Tifab protein networkhttps://string-db.org/network/10090.ENSMUSP00000131162TRAF-interacting protein with FHA domain-containing protein B; Inhibits TIFA-mediated TRAF6 activation possibly by inducing a conformational change in TIFA.
G6pd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131163Glucose-6-phosphate 1-dehydrogenase 2; Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shu [...]
Apopt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131169Cytochrome c oxidase assembly factor 8; Required for cytochrome c complex (COX) IV assembly and function Protects COX assembly from oxidation-induced degradation, COX being the terminal component [...]
Pycr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131199Pyrroline-5-carboxylate reductase 1, mitochondrial; Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Invol [...]
1700093K21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000131204Uncharacterized protein C2orf74 homolog.
Eefsec protein networkhttps://string-db.org/network/10090.ENSMUSP00000131207Selenocysteine-specific elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine direc [...]
Vmn2r7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131220Vomeronasal 2, receptor 7.
Pilrb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131233Paired immunoglobulin-like type 2 receptor beta-2; Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. P [...]
Ppt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131243Lysosomal thioesterase PPT2; Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and [...]
Zscan4-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131258Zinc finger and SCAN domain containing 4, pseudogene 1.
Vmn2r98 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131261Vomeronasal 2, receptor 98.
4933411K16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000131279Uncharacterized protein C10orf62 homolog.
Trim30b protein networkhttps://string-db.org/network/10090.ENSMUSP00000131288Tripartite motif-containing 30B.
H2-M2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131297Histocompatibility 2, M region locus 2; Belongs to the MHC class I family.
Skint3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131300Selection and upkeep of intraepithelial T-cells protein 3; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus.
Rergl protein networkhttps://string-db.org/network/10090.ENSMUSP00000131303RERG/RAS-like.
Gm8122 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131304Predicted gene 8122.
Rbms1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131306RNA-binding motif, single-stranded-interacting protein 1; Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif [...]
Slc17a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131308Solute carrier family 17 (sodium phosphate), member 3.
Hspg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131316Basement membrane-specific heparan sulfate proteoglycan core protein; Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed nega [...]
Gmeb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131331Glucocorticoid modulatory element-binding protein 1; Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increas [...]
Gm21103 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131334Predicted gene, 21103.
Ulk4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131342Serine/threonine-protein kinase ULK4; May be involved in the remodeling of cytoskeletal components, such as alpha-tubulin, and in this way regulates neurite branching and elongation, as well as c [...]
Gm3248 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131346Predicted gene 3248.
Glg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131355Golgi apparatus protein 1; Binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils).
H2-M5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131365Histocompatibility 2, M region locus 5; Belongs to the MHC class I family.
Rbms3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131371RNA-binding motif, single-stranded-interacting protein 3; Binds poly(A) and poly(U) oligoribonucleotides.
Rnf19b protein networkhttps://string-db.org/network/10090.ENSMUSP00000131373E3 ubiquitin-protein ligase RNF19B; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transf [...]
Ssr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131386Translocon-associated protein subunit delta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
Gm21292 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131393Predicted gene, 21292.
Sspo protein networkhttps://string-db.org/network/10090.ENSMUSP00000131401SCO-spondin; Involved in the modulation of neuronal aggregation. May be involved in developmental events during the formation of the central nervous system (By similarity); Belongs to the thrombo [...]
Ppp1r12b protein networkhttps://string-db.org/network/10090.ENSMUSP00000131406Protein phosphatase 1 regulatory subunit 12B; Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus (By similarity).
Neu2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131409Sialidase-2; Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins, oligosaccharides and gangliosides; Belongs to the glycosyl hydrolase 33 family.
Lrriq1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131419Leucine-rich repeat and IQ domain-containing protein 1.
Snx24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131423Sorting nexin-24; May be involved in several stages of intracellular trafficking.
Vmn2r83 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131426Vomeronasal 2, receptor 83.
F830016B08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000131437Interferon-gamma-inducible GTPase Ifgga4 protein.
Syce2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131438Synaptonemal complex central element protein 2; Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. R [...]
Parvg protein networkhttps://string-db.org/network/10090.ENSMUSP00000131443Gamma-parvin; Probably plays a role in the regulation of cell adhesion and cytoskeleton organization; Belongs to the parvin family.
Vmn2r115 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131447Vomeronasal 2, receptor 115.
Vmn2r17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131450Vomeronasal 2, receptor 17.
Supt20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131454Transcription factor SPT20 homolog; Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulati [...]
Nup50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131457Nuclear pore complex protein Nup50; Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembl [...]
Cpvl protein networkhttps://string-db.org/network/10090.ENSMUSP00000131462Probable serine carboxypeptidase CPVL; May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for [...]
Fam98c protein networkhttps://string-db.org/network/10090.ENSMUSP00000131477Family with sequence similarity 98, member C.
Kcnf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131480Potassium voltage-gated channel subfamily F member 1; Putative voltage-gated potassium channel; Belongs to the potassium channel family. F (TC 1.A.1.2) subfamily. Kv5.1/KCNF1 sub-subfamily.
Gm8220 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131482Predicted gene 8220.
Rpl14 protein networkhttps://string-db.org/network/10090.ENSMUSP0000013148960S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family.
Vgll3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131500Transcription cofactor vestigial-like protein 3; May act as a specific coactivator for the mammalian TEFs. Belongs to the vestigial family.
Cyp11b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131503Cytochrome P450 11B2, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the biosynthesis of adrenal mineralocorticoid aldosterone. Catalyzes three sequential oxidative reactions of 11 [...]
Pacsin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131504Protein kinase C and casein kinase substrate in neurons protein 2; Regulates the morphogenesis and endocytosis of caveolae. Lipid-binding protein that is able to promote the tubulation of the pho [...]
Isoc2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000131514Isochorismatase domain-containing protein 2A.
Dthd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131534Death domain-containing 1.
Phf11c protein networkhttps://string-db.org/network/10090.ENSMUSP00000131536PHD finger protein 11C.
Timd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131540T-cell immunoglobulin and mucin domain-containing protein 2; Probable receptor for SEMA4A involved in the regulation of T- cell function. The interaction with SEMA4A enhances T-cell activation. B [...]
Vmn2r96 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131564Vomeronasal 2, receptor 96.
Herc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131573E3 ubiquitin-protein ligase HERC2; E3 ubiquitin-protein ligase that regulates ubiquitin- dependent retention of repair proteins on damaged chromosomes. Recruited to sites of DNA damage in respons [...]
Cox7a2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000131584Cytochrome c oxidase subunit 7A-related protein, mitochondrial; Involved in the regulation of oxidative phosphorylation and energy metabolism. Necessary for the assembly of mitochondrial respirat [...]
Rcbtb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131588RCC1 and BTB domain-containing protein 2.
Gm4302 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131605Predicted gene 4302.
Fam78b protein networkhttps://string-db.org/network/10090.ENSMUSP00000131620Protein FAM78B; Belongs to the FAM78 family.
Carns1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131624Carnosine synthase 1; Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine.
Kcnj1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131625ATP-sensitive inward rectifier potassium channel 1; In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendenc [...]
Pdc protein networkhttps://string-db.org/network/10090.ENSMUSP00000131631Phosducin; Inhibits the transcriptional activation activity of the cone- rod homeobox CRX (By similarity). May participate in the regulation of visual phototransduction or in the integration of p [...]
Rsph14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131632Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family.
Rsph4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000131647Radial spoke head protein 4 homolog A; Probable component of the axonemal radial spoke head (By similarity). Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They cons [...]
Gng13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131648Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling s [...]
Gcat-2 protein networkhttps://string-db.org/network/10090.ENSMUSP000001316492-amino-3-ketobutyrate coenzyme A ligase, mitochondrial.
Nell2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131665Protein kinase C-binding protein NELL2; Required for neuron survival through the modulation of MAPK pathways (By similarity). Involved in the regulation of hypothalamic GNRH secretion and the con [...]
Mark2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131684Serine/threonine-protein kinase MARK2; Serine/threonine-protein kinase. Involved in cell polarity and microtubule dynamics regulation. Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4 a [...]
Vmn1r135 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131702Vomeronasal 1 receptor 135.
Fam168b protein networkhttps://string-db.org/network/10090.ENSMUSP00000131720Myelin-associated neurite-outgrowth inhibitor; Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC [...]
Gm20498 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131728Predicted gene 20498.
Dhx37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131734DEAH (Asp-Glu-Ala-His) box polypeptide 37.
Eci2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131735Enoyl-CoA delta isomerase 2, mitochondrial; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (B [...]
Slc39a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131736Zinc transporter ZIP5; May play a role in polarized cells by carrying out serosal- to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic [...]
Mmel1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131753Membrane metallo-endopeptidase-like 1, soluble form; Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a [...]
Olfr819 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131761Olfactory receptor.
Syce3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131766Synaptonemal complex central element protein 3; Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. R [...]
9430015G10Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000131817RIKEN cDNA 9430015G10 gene.
Iqcf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131823IQ motif-containing F6.
Cnnm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131830Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family.
Vmn2r6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131831Vomeronasal 2, receptor 6.
Plxna1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131840Plexin-A1; Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive [...]
Zfp839 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131841Zinc finger protein 839.
Gemin5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131842Gem-associated protein 5; Required for the assembly of the SMN complex that plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceos [...]
Nutf2-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131850Nuclear transport factor 2, pseudogene 1.
Gm15056 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131853Predicted gene 15056.
Smim19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131855Small integral membrane protein 19.
Vmn2r59 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131856Vomeronasal 2, receptor 59.
Sla protein networkhttps://string-db.org/network/10090.ENSMUSP00000131865Src-like-adapter; Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved [...]
Vmn1r259 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131872Vomeronasal 1 receptor 259.
Snx19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131895Sorting nexin-19; Plays a role in intracellular vesicle trafficking and exocytosis. May play a role in maintaining insulin- containing dense core vesicles in pancreatic beta-cells and in preventi [...]
Cfap74 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131899Cilia- and flagella-associated protein 74; As part of the central apparatus of the cilium axoneme may play a role in cilium movement.
Fam102b protein networkhttps://string-db.org/network/10090.ENSMUSP00000131904Protein FAM102B; Belongs to the FAM102 family.
5830411N06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000131905RIKEN cDNA 5830411N06 gene.
Vmn2r5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131925Vomeronasal 2, receptor 5.
Oser1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131932Oxidative stress-responsive serine-rich protein 1.
Fcgr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131938Low affinity immunoglobulin gamma Fc region receptor III; Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor which binds to IgG1, IgG2a and IgG2b. Mediates neutr [...]
Smim12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131941Small integral membrane protein 12.
Slc29a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131976Equilibrative nucleoside transporter 1; Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor [...]
Vmn2r29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131990Vomeronasal 2, receptor 29.
Tnnc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000131991Troponin C, slow skeletal and cardiac muscles; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosi [...]
Cypt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132007Cysteine-rich perinuclear theca 2.
Arhgap8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132008Rho GTPase-activating protein 8; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Hsd17b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132011Testosterone 17-beta-dehydrogenase 3; Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH. Belongs to the short-chain dehydrogenases/re [...]
Gm8922 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132013Predicted gene 8922.
Vmn2r22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132043Vomeronasal 2, receptor 22.
Vrtn protein networkhttps://string-db.org/network/10090.ENSMUSP00000132050Vertnin; Belongs to the vertnin family.
Lats1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132078Serine/threonine-protein kinase LATS1; Negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation [...]
Iars protein networkhttps://string-db.org/network/10090.ENSMUSP00000132082Isoleucine--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and [...]
Dpy19l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132092Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins. Required during spermatogenesis for sperm head elon [...]
Banp protein networkhttps://string-db.org/network/10090.ENSMUSP00000132095Protein BANP; Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an AT [...]
Ptp4a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132097Protein tyrosine phosphatase type IVA 3; Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive act [...]
Gen1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132098Flap endonuclease GEN homolog 1; Endonuclease which resolves Holliday junctions (HJs) by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex product [...]
Tgfb1i1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132100Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleu [...]
Rps27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132102Ribosomal protein S27.
Gm8926 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132103Predicted gene 8926.
Gm42421 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132104Predicted gene, 42421.
Ccdc24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132114Coiled-coil domain-containing 24.
Wac protein networkhttps://string-db.org/network/10090.ENSMUSP00000132117WW domain-containing adapter protein with coiled-coil; Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Interacts with the RNA polymerase [...]
Gm3269 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132121Predicted gene 3269.
2610042L04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000132127RIKEN cDNA 2610042L04 gene.
Psmb11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132140Proteasome subunit beta type-11; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the le [...]
Galnt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132142Polypeptide N-acetylgalactosaminyltransferase 1 soluble form; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a ser [...]
Tmem102 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132164Transmembrane protein 102; Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway.
Gm3594 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132178Predicted gene 3594.
Cyp2j11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132180Cytochrome P450, family 2, subfamily j, polypeptide 11; Belongs to the cytochrome P450 family.
Gm38392 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132187Predicted gene, 38392.
Phykpl protein networkhttps://string-db.org/network/10090.ENSMUSP000001321905-phosphohydroxy-L-lysine phospho-lyase; Catalyzes the pyridoxal-phosphate-dependent breakdown of 5- phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semi [...]
Smim26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132193Small integral membrane protein 26.
Prss57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132215Serine protease 57; Serine protease that cleaves preferentially after Arg residues. Can also cleave after citrulline (deimidated arginine) and methylarginine residues; Belongs to the peptidase S1 [...]
Adamts3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132219A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3.
Ddx39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132222ATP-dependent RNA helicase DDX39A; Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus (By similarity).
Wwp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132224NEDD4-like E3 ubiquitin-protein ligase WWP2; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the [...]
Gm8020 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132236Predicted gene 8020.
Olfr288 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132237Olfactory receptor.
Tex264 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132247Testis-expressed gene 264.
Usf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132256Upstream stimulatory factor 2; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
Gm3250 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132276Predicted gene 3250.
Gm3752 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132286Predicted gene 3752.
Gtf2e2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132287General transcription factor IIE subunit 2; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Bo [...]
Dnajc28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132288DnaJ homolog subfamily C member 28; May have a role in protein folding or as a chaperone.
Zfp558 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132305Zinc finger protein 558.
Skor2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132338SKI family transcriptional corepressor 2; Acts as a TGF-beta antagonist in the nervous system (By similarity). Exhibits transcriptional repressor activity.
Trgc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132340T-cell receptor gamma chain C region C7.5.
Sec61g protein networkhttps://string-db.org/network/10090.ENSMUSP00000132348Protein transport protein Sec61 subunit gamma; Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic [...]
Cic protein networkhttps://string-db.org/network/10090.ENSMUSP00000132351Protein capicua homolog; Transcriptional repressor which plays a role in development of the central nervous system (CNS). In concert with ATXN1 and ATXN1L, involved in brain development.
Rrh protein networkhttps://string-db.org/network/10090.ENSMUSP00000132360Visual pigment-like receptor peropsin; May play a role in rpe physiology either by detecting light directly or by monitoring the concentration of retinoids or other photoreceptor-derived compound [...]
Zfp710 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132361Zinc finger protein 710; May be involved in transcriptional regulation.
Apold1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132366Apolipoprotein L domain-containing 1.
Pde7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000132378cAMP-specific 3',5'-cyclic phosphodiesterase 7B; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-m [...]
Gm10722 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132394Predicted gene 10722.
Ms4a6c protein networkhttps://string-db.org/network/10090.ENSMUSP00000132425Membrane-spanning 4-domains subfamily A member 6C; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family.
Gm5861 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132429Predicted gene 5861.
Gbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132435Guanylate-binding protein 2; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP (By similarity). Exhibits antiviral activity against influenza virus. [...]
Zfp488 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132436Zinc finger protein 488; Transcriptional repressor. Plays a role in oligodendrocyte differentiation, together with OLIG2. Mediates Notch signaling-activated formation of oligodendrocyte precursor [...]
Mrps12 protein networkhttps://string-db.org/network/10090.ENSMUSP0000013244328S ribosomal protein S12, mitochondrial; Belongs to the universal ribosomal protein uS12 family.
Ube2d2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000132446Ubiquitin-conjugating enzyme E2 D2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Mediates [...]
Atxn10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132450Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycos [...]
Ccr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132453C-C chemokine receptor type 2; Key functional receptor for CCL2 but can also bind CCL7 and CCL12 chemokines. Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration i [...]
Gm7714 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132464Predicted gene 7714.
Gm3755 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132468Predicted gene 3755.
Skint5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132470Selection and upkeep of intraepithelial T-cells protein 5; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus.
BC035947 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132488cDNA sequence BC035947.
Tex10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132498Testis-expressed protein 10; Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation [...]
Prkag1 protein networkhttps://string-db.org/network/10090.ENSMUSP000001324995'-AMP-activated protein kinase subunit gamma-1; AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energ [...]
Zfp101 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132508Zinc finger protein 101.
Lpar5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132511Lysophosphatidic acid receptor 5; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities; Belongs to the G-protein coupled receptor 1 family.
Cacna2d2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132512Voltage-dependent calcium channel subunit alpha-2/delta-2; The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics o [...]
Katna1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132514Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular mi [...]
Dus1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000132516tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the Dus family. Dus1 subfamily.
Emp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132519Epithelial membrane protein 3; Probably involved in cell proliferation and cell-cell interactions; Belongs to the PMP-22/EMP/MP20 family.
Gm8369 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132521Predicted gene 8369.
Adcy7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132528Adenylate cyclase type 7; Catalyzes the formation of cAMP in response to activation of G protein-coupled receptors (Probable). Functions in signaling cascades activated namely by thrombin and sph [...]
Apol11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000132565Apolipoprotein L 11a.
Gm20390 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132590Nucleoside diphosphate kinase.
Ier5l protein networkhttps://string-db.org/network/10090.ENSMUSP00000132594Immediate early response gene 5-like protein; Belongs to the IER family.
Gbe1 protein networkhttps://string-db.org/network/10090.ENSMUSP000001326031,4-alpha-glucan-branching enzyme; Required for normal glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule.
Hp1bp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132614Heterochromatin protein 1-binding protein 3; Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically inf [...]
Speer1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132617Spermatogenesis associated glutamate (E)-rich protein 1.
Adgrg5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132628Adhesion G-protein coupled receptor G5; Adhesion G protein-coupled receptor (GPCR). Transduces intracellular signals through coupling to guanine nucleotide-binding protein G(s) subunit alpha and [...]
Prr13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132636Proline-rich protein 13; Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane-induced apoptosis (By similarity).
Magea5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132644Melanoma antigen, family A, 5.
Gm6169 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132645Predicted gene 6169.
Shisa9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132646Protein shisa-9; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA re [...]
Pate10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132657Secreted TFP/Ly-6/uPAR protein PATE-N.
Scgb1b19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132661Secretoglobin, family 1B, member 19.
Dis3l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132673DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation [...]
Prol1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132678Proline-rich, lacrimal 1.
Rsph10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000132687Radial spoke head 10 homolog B (Chlamydomonas).
Cnppd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132688Protein CNPPD1.
Rasl10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000132696Ras-like protein family member 10B; May facilitate the release of atrial natriuretic peptide by cardiomyocytes and hence play a role in the regulation of arterial pressure; Belongs to the small G [...]
Krtap19-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132718Keratin-associated protein 19-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Ciao2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000132725Cytosolic iron-sulfur assembly component 2B; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster i [...]
Vmn2r69 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132726Vomeronasal 2, receptor 69.
Gm8229 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132728Predicted gene 8229.
Hnrnpd protein networkhttps://string-db.org/network/10090.ENSMUSP00000132735Heterogeneous nuclear ribonucleoprotein D0; Binds with high affinity to RNA molecules that contain AU- rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Als [...]
Rnf41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132751E3 ubiquitin-protein ligase NRDP1; Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins. Polyubiquitinates MYD88 (By similarity). Negatively regulates MYD88-depend [...]
Tstd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132771Thiosulfate sulfurtransferase (rhodanese)-like domain-containing 1.
Cd59a protein networkhttps://string-db.org/network/10090.ENSMUSP00000132774CD59A glycoprotein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporatio [...]
Idi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132780Isopentenyl-diphosphate Delta-isomerase 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosp [...]
Ifit1bl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132781Interferon-induced protein with tetratricpeptide repeats 1B-like 1.
Baalc protein networkhttps://string-db.org/network/10090.ENSMUSP00000132788Brain and acute leukemia cytoplasmic protein; May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A.
Gm5415 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132789Predicted gene 5415.
Slc8a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132809Sodium/calcium exchanger 1; Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) leve [...]
Dlc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132812Rho GTPase-activating protein 7; Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological chan [...]
Prss51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132814Protease, serine 51.
Phlda1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132815Pleckstrin homology-like domain family A member 1; Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neur [...]
Xpnpep3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132822Xaa-Pro aminopeptidase 3; Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala. Also shows low activity towards peptides with Ala or Ser at th [...]
Sult6b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132823Sulfotransferase 6B1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of thyroxine. Involved in the metabolism of thyro [...]
Gm8247 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132825Predicted gene 8247.
Cyp2c69 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132832Cytochrome P450, family 2, subfamily c, polypeptide 69; Belongs to the cytochrome P450 family.
Olfr1116 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132837Olfactory receptor.
Sfta2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132839Surfactant-associated protein 2; Putative surfactant protein.
Fam178b protein networkhttps://string-db.org/network/10090.ENSMUSP00000132846Protein FAM178B.
Sept2-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132850Septin 2.
Hsbp1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132852Heat shock factor-binding protein 1-like protein 1; Belongs to the HSBP1 family.
Lrrc10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000132865Leucine-rich repeat-containing 10B.
Dbf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132906Protein DBF4 homolog A; Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role DNA in replication and cell proliferation. Required for progression of S pha [...]
Armcx4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132914Armadillo repeat-containing, X-linked 4.
Omg protein networkhttps://string-db.org/network/10090.ENSMUSP00000132918Oligodendrocyte-myelin glycoprotein; Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.
Ergic1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132922Endoplasmic reticulum-Golgi intermediate compartment protein 1; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the ERGIC family.
H2al2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000132924H2A histone family member L2B.
Rab3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000132945Ras-related protein Rab-3C; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.
Cd2bp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132963CD2 antigen cytoplasmic tail-binding protein 2; Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly.
Zfp54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132983Zinc finger protein 54; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Gm4027 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132993Predicted gene 4027.
Tmem273 protein networkhttps://string-db.org/network/10090.ENSMUSP00000132997Transmembrane protein 273.
Vmn2r35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133007Vomeronasal 2, receptor 35.
Cd36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133008Platelet glycoprotein 4; Multifunctional glycoprotein that acts as receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyl [...]
Vmn2r72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133014Vomeronasal 2, receptor 72.
Retn protein networkhttps://string-db.org/network/10090.ENSMUSP00000133024Resistin; Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes; Belongs to the resistin/FIZZ family.
Tma7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133026Translation machinery-associated protein 7; Belongs to the TMA7 family.
Lin52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133045Protein lin-52 homolog.
Spats2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000133054SPATS2-like protein; Belongs to the SPATS2 family.
Gm4884 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133059Predicted gene 4884.
Cntn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133063Contactin-1; Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the [...]
Fgfr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133064Fibroblast growth factor receptor 3; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, [...]
Kcnn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133065Intermediate conductance calcium-activated potassium channel protein 4; Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membran [...]
Tnpo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133076Transportin-2; Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate doc [...]
Olfr976 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133083Olfactory receptor MOR224-10.
Olfr270 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133100Olfactory receptor.
Gm3667 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133107Predicted gene 3667.
Prr36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133114Proline-rich 36.
Fga protein networkhttps://string-db.org/network/10090.ENSMUSP00000133117Fibrinogen alpha chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fi [...]
P2ry10b protein networkhttps://string-db.org/network/10090.ENSMUSP00000133122Purinergic receptor P2Y, G-protein-coupled 10B.
Fam172a protein networkhttps://string-db.org/network/10090.ENSMUSP00000133140Cotranscriptional regulator FAM172A; Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7. Seems to be required for stabilizing protein-protein interactions a [...]
Zbtb42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133152Zinc finger and BTB domain-containing protein 42; Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes; Belongs to the kru [...]
Pdzrn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133159PDZ domain-containing RING finger 4.
Gm2237 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133164Predicted gene 2237.
Erap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133166Endoplasmic reticulum aminopeptidase 1; Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is [...]
Klhl25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133175Kelch-like protein 25; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by med [...]
Krtap19-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133176Keratin-associated protein 19-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Gm17571 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133186Predicted gene, 17571.
Taar8c protein networkhttps://string-db.org/network/10090.ENSMUSP00000133193Trace amine-associated receptor 8c; Orphan olfactory receptor specific for trace amines. Belongs to the G-protein coupled receptor 1 family.
Pcid2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133204PCI domain-containing protein 2; Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation. As a component of the [...]
Zfp641 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133212Zinc finger protein 641; Transcriptional activator. Activates transcriptional activities of SRE and AP-1 (By similarity).
Atg7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133215Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 [...]
Vmn2r11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133218Vomeronasal 2, receptor 11.
Ddx46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133245Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation.
Skint8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133268Selection and upkeep of intraepithelial T-cells protein 8; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus.
Gm3015 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133272Predicted gene 3015.
Pdzd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133273PDZ domain-containing protein 7; In cochlear developing hair cells, essential in organizing the USH2 complex at stereocilia ankle links. Blocks inhibition of adenylate cyclase activity mediated b [...]
Prdx6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000133276Peroxiredoxin 6, related sequence 1.
Tet1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133279Methylcytosine dioxygenase TET1; Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active D [...]
Xpo4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133280Exportin-4; Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. [...]
Hoxb6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133281Homeobox protein Hox-B6; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterio [...]
Apoe protein networkhttps://string-db.org/network/10090.ENSMUSP00000133302Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstiti [...]
Znrf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133309E3 ubiquitin-protein ligase ZNRF1; E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL, thereby playing a role in neuron cells differentiation. Plays a role in the estab [...]
Ndst4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133341Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosam [...]
Vmn1r243 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133350Vomeronasal type-1 receptor.
Hap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133356Huntingtin-associated protein 1; Originally identified as neuronal protein that specifically associates with HTT/huntingtin and the binding is enhanced by an expanded polyglutamine repeat within [...]
Sra1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133360Steroid receptor RNA activator 1; Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mec [...]
Mpig6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000133377Megakaryocyte and platelet inhibitory receptor G6b; Inhibitory receptor that acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production. [...]
Ppp2r1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000133404Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the cat [...]
Ddx39b protein networkhttps://string-db.org/network/10090.ENSMUSP00000133428Spliceosome RNA helicase Ddx39b; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and n [...]
Dyrk1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000133431Dual specificity tyrosine-phosphorylation-regulated kinase 1B; Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activity. Enhances the transcriptional activity of [...]
Moap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133459Modulator of apoptosis 1; Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response [...]
Ptprd protein networkhttps://string-db.org/network/10090.ENSMUSP00000133468Receptor-type tyrosine-protein phosphatase delta; Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically [...]
Pear1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133474Platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells; Belongs to the MEGF family.
Baz1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000133478Bromodomain adjacent to zinc finger domain protein 1A; Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate eve [...]
Vmn2r55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133483Vomeronasal 2, receptor 55; Belongs to the G-protein coupled receptor 3 family.
Msx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133484Homeobox protein MSX-3; Acts as a potent transcriptional repressor of MSX1. Belongs to the Msh homeobox family.
Psmb9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133499Proteasome subunit beta type-9; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the lea [...]
Ly6g6c protein networkhttps://string-db.org/network/10090.ENSMUSP00000133510Lymphocyte antigen 6 complex locus protein G6c.
Ube2g2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133515Ubiquitin-conjugating enzyme E2 G2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Involved [...]
Cct4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133523T-complex protein 1 subunit delta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC comple [...]
Dnm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133564Dynamin-2; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon g [...]
Vmn1r246 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133598Vomeronasal type-1 receptor.
Gm20604 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133604Predicted gene 20604.
Vmn1r245 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133606Vomeronasal type-1 receptor.
Vmn1r253 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133608Vomeronasal 1 receptor 253.
Nkx1-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133620NK1 homeobox 1.
Adamtsl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133637ADAMTS-like 3.
Speer4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000133641Spermatogenesis-associated glutamate (E)-rich protein 4C.
Gm10767 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133647Predicted gene 10767.
Syncrip protein networkhttps://string-db.org/network/10090.ENSMUSP00000133649Heterogeneous nuclear ribonucleoprotein Q; Heterogeneous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA s [...]
Mocs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133694Cyclic pyranopterin monophosphate synthase; Isoform Mocs1a and isoform Mocs1b probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). Mocs1a c [...]
Smim6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133699Small integral membrane protein 6.
Aif1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133709Allograft inflammatory factor 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signali [...]
Mgat4e protein networkhttps://string-db.org/network/10090.ENSMUSP00000133717Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4E; Glycosyltransferase-like protein that may participate in the transfer of N-acetylglucosamine (GlcNAc) t [...]
Hnrnpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000133728Heterogeneous nuclear ribonucleoprotein L; Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for [...]
Gm16451 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133729Predicted pseudogene 16451.
Prps1l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133736Phosphoribosyl pyrophosphate synthetase 1-like 3.
Olfr301 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133780Olfactory receptor Olfr301.
Lig3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133805DNA ligase 3; The alpha isoform interacts with DNA-repair protein XRCC1 and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation [...]
Dip2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000133806Disco-interacting protein 2 homolog C.
Cyp2j12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133811Cytochrome P450, family 2, subfamily j, polypeptide 12; Belongs to the cytochrome P450 family.
Hspa1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000133815Heat shock 70 kDa protein 1B; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized [...]
Rbm38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133816RNA-binding protein 38; RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p [...]
Zfp57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133821Zinc finger protein 57; Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner [...]
Olfr138 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133828Olfactory receptor.
Vmn2r34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133841Vomeronasal 2, receptor 34.
Ubtf protein networkhttps://string-db.org/network/10090.ENSMUSP00000133844Nucleolar transcription factor 1; Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription facto [...]
Nat8f6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133846N-acetyltransferase family 8 member 3; Has histone acetyltransferase activity in vitro, with specificity for histone H4.
Gps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133855COP9 signalosome complex subunit 1; Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential [...]
Olfr121 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133865Olfactory receptor.
Fam71e2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133885Family with sequence similarity 71, member E2.
Vmn1r172 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133887Vomeronasal type-1 receptor.
Arhgap32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133898Rho GTPase-activating protein 32; GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during t [...]
Zfp141 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133899Zinc finger protein 141.
Vmn1r256 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133911Vomeronasal 1 receptor 256.
Dio3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133920Thyroxine 5-deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronin [...]
Gm21671 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133924Predicted gene, 21671.
Prps1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133931Phosphoribosyl pyrophosphate synthetase 1-like 1.
Setd1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000133933Histone-lysine N-methyltransferase SETD1B; Histone methyltransferase that specifically methylates 'Lys- 4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if [...]
Gcnt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133935Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase; Glycosyltransferase that catalyzes the transfer of an N- acetylglucosamine moiety onto mucin-type core 1 O-gl [...]
Otud4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133939OTU domain-containing protein 4; Deubiquitinase which hydrolyzes the isopeptide bond between the ubiquitin C-terminus and the lysine epsilon-amino group of the target protein. May negatively regu [...]
Gm2381 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133949Predicted gene 2381.
Trim15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133953Tripartite motif-containing 15.
Esp31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133965Exocrine gland-secreting peptide 31.
L3mbtl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133967Lethal(3)malignant brain tumor-like protein 2; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromat [...]
Vmn1r158 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133990Vomeronasal type-1 receptor.
Scyl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000133992SCY1-like protein 2; Component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. May be a serine/threonine-protein kinase. May regulate clathrin [...]
Gm20403 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134012Predicted gene 20403.
Znhit2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134031Zinc finger HIT domain-containing protein 2; May act as a bridging factor mediating the interaction between the R2TP/Prefoldin-like (R2TP/PFDL) complex and U5 small nuclear ribonucleoprotein (U5 [...]
Zic4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134053Zinc finger protein ZIC 4; Binds to DNA; Belongs to the GLI C2H2-type zinc-finger protein family.
Zmym5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134057Zinc finger MYM-type protein 5; Functions as a transcriptional regulator.
Iffo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134062Intermediate filament family orphan 2; Belongs to the intermediate filament family.
Spag17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134066Sperm-associated antigen 17; Component of the central pair apparatus of ciliary axonemes. Plays a critical role in the function and structure of motile cilia. May play a role in endochondral bone [...]
Uncx protein networkhttps://string-db.org/network/10090.ENSMUSP00000134067Homeobox protein unc-4 homolog; Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May [...]
A930009A15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000134099RIKEN cDNA A930009A15 gene.
Gm20441 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134112Predicted gene 20441.
Evx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134131Homeobox even-skipped homolog protein 2.
H2-Q10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134163H-2 class I histocompatibility antigen, Q10 alpha chain; Involved in the presentation of foreign antigens to the immune system.
Vmn1r62 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134168Vomeronasal type-1 receptor.
Ube2i protein networkhttps://string-db.org/network/10090.ENSMUSP00000134169SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help [...]
Ak9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134177Adenylate kinase 9.
Jarid2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134205Protein Jumonji; Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hema [...]
Mex3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000134222Mex3 RNA-binding family member A.
Rgs22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134259Regulator of G-protein signaling 22; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
Slit2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134263Slit homolog 2 protein C-product; Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neur [...]
Wdr81 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134266WD repeat-containing protein 81; Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying [...]
Ttc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134273Tetratricopeptide repeat domain 6.
Mecom protein networkhttps://string-db.org/network/10090.ENSMUSP00000134303Histone-lysine N-methyltransferase MECOM.
Gypc protein networkhttps://string-db.org/network/10090.ENSMUSP00000134317Glycophorin-C.
Cyp2j7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134331Cytochrome P450, family 2, subfamily j, polypeptide 7; Belongs to the cytochrome P450 family.
Scnm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134337Sodium channel modifier 1; Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.
Gm19684 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134339Predicted gene, 19684.
2410141K09Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000134352RIKEN cDNA 2410141K09 gene.
Vmn1r180 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134362Vomeronasal type-1 receptor.
Isx protein networkhttps://string-db.org/network/10090.ENSMUSP00000134368Intestine-specific homeobox; Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine.
Olfr297 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134371Olfactory receptor Olfr297.
Olfr309 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134377Olfactory receptor Olfr309.
Pja2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134380E3 ubiquitin-protein ligase Praja-2; Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulator [...]
Chek1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134388Serine/threonine-protein kinase Chk1; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA d [...]
Crx protein networkhttps://string-db.org/network/10090.ENSMUSP00000134400Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin gen [...]
Sumo3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134416Small ubiquitin-related modifier 3; Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in pr [...]
Vmn2r126 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134441Vomeronasal 2, receptor 126.
Dmbx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134457Diencephalon/mesencephalon homeobox protein 1; Functions as a transcriptional repressor. May repress OTX2- mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3 [...]
Gm20509 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134473Predicted gene 20509.
D7Ertd443e protein networkhttps://string-db.org/network/10090.ENSMUSP00000134479(E2-independent) E3 ubiquitin-conjugating enzyme FATS; Tumor suppressor that is required to sustain G2/M checkpoint after DNA damage. Acts as a p53/TP53 activator by inhibiting MDM2 binding to p5 [...]
Klrb1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000134504Killer cell lectin-like receptor subfamily B member 1C; Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization [...]
Gm20503 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134530Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta a [...]
Obox3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134531Oocyte-specific homeobox 3.
Olfr103 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134539Olfactory receptor.
H2-Q6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134550H-2 class I histocompatibility antigen, Q8 alpha chain; Involved in the presentation of foreign antigens to the immune system.
Actl9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134564Actin-like protein 9.
Abhd12b protein networkhttps://string-db.org/network/10090.ENSMUSP00000134568Abhydrolase domain-containing 12B.
H2-D1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134570H-2 class I histocompatibility antigen, D-B alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family.
Kifc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134572Kinesin-like protein KIFC1; Minus end-directed microtubule-dependent motor required for bipolar spindle formation. May contribute to movement of early endocytic vesicles. Regulates cilium formati [...]
Cfap221 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134576Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis. Belongs to the PCDP1 family.
Cyp2j8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134591Cytochrome P450, family 2, subfamily j, polypeptide 8; Belongs to the cytochrome P450 family.
Tmem29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134594Transmembrane protein 29.
Rps28 protein networkhttps://string-db.org/network/10090.ENSMUSP0000013461540S ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family.
Vax1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134642Ventral anterior homeobox 1; Transcription factor that may function in dorsoventral specification of the forebrain. Required for axon guidance and major tract formation in the developing forebrai [...]
Ifi206 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134646Interferon-activated gene 206.
Vmn1r255 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134659Vomeronasal 1 receptor 255.
Pax2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134661Paired box protein Pax-2; Transcription factor that may have a role in kidney cell differentiation.
Gprasp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134666G-protein coupled receptor-associated sorting protein 2; May play a role in regulation of a variety of G-protein coupled receptors.
1700067K01Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000134671UPF0575 protein C19orf67 homolog; Belongs to the UPF0575 family.
Pla2g6 protein networkhttps://string-db.org/network/10090.ENSMUSP0000013467285/88 kDa calcium-independent phospholipase A2; Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide- induced or vasopre [...]
Csnk2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000134673Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit (By similarity). Participates in Wnt signaling; Belongs to the casein kinase 2 [...]
Smpd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134687Sphingomyelin phosphodiesterase 5.
Psme1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134735Proteasome activator complex subunit 1; Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I bindin [...]
Cyhr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134739Cysteine and histidine-rich protein 1; Belongs to the CYHR1 family.
H3c14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134751H3 clustered histone 14.
Traf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134759E3 ubiquitin-protein ligase TRAF7; E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3. Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DD [...]
Rnf141 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134781RING finger protein 141; May be involved in spermatogenesis.
Golph3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000134799Golgi phosphoprotein 3-like; Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and antero [...]
Cpsf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134823Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation pr [...]
Asap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134825Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1; May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly o [...]
Vmn1r69 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134833Vomeronasal type-1 receptor.
Higd1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000134848HIG1 domain family, member 1C.
Zeb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134849Zinc finger E-box-binding homeobox 2; Transcriptional inhibitor that binds to DNA sequence 5'- CACCT-3' in different promoters. Represses transcription of E-cadherin; Belongs to the delta-EF1/ZFH [...]
Stx5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000134854Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked [...]
Apol7a protein networkhttps://string-db.org/network/10090.ENSMUSP00000134864Apolipoprotein L 7a.
Ppp1r3e protein networkhttps://string-db.org/network/10090.ENSMUSP00000134894Protein phosphatase 1 regulatory subunit 3E; Acts as a glycogen-targeting subunit for PP1. PP1 is involved in glycogen metabolism and contributes to the activation of glycogen synthase leading to [...]
Peg10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000134963Retrotransposon-derived protein PEG10; May have a role in cell growth promotion, apoptotic resistance and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta rece [...]
Ly6l protein networkhttps://string-db.org/network/10090.ENSMUSP00000134982Lymphocyte antigen 6L.
Chtf8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135029Chromosome transmission fidelity protein 8 homolog; Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear [...]
Gfi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135039Zinc finger protein Gfi-1; Transcription repressor essential for hematopoiesis. Functions in a cell-context and development-specific manner. Binds to 5'-TAAATCAC[AT]GCA-3' in the promoter region [...]
Tppp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135040Tubulin polymerization-promoting protein family member 3; Regulator of microtubule dynamic that has microtubule bundling activity (By similarity). Required for embryo implantation; possibly by re [...]
Wfikkn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135083WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1; Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metallopro [...]
Phgr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135093Proline, histidine and glycine-rich protein 1.
Pou1f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135113Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituita [...]
Pou2f3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135115POU domain, class 2, transcription factor 3; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'); Belongs to the POU transcription factor family. Class-2 subfamily.
Cdhr4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135184Cadherin-related family member 4.
Vmn2r-ps130 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135186Vomeronasal 2, receptor, pseudogene 130.
H3c15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135215H3 clustered histone 15.
Taf6l protein networkhttps://string-db.org/network/10090.ENSMUSP00000135220TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating hi [...]
Cux1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135223Homeobox protein cut-like 1; Transcription factor involved in the control of neuronal differentiation in the brain. Regulates dendrite development and branching, and dendritic spine formation in [...]
Vmn2r99 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135236Vomeronasal 2, receptor 99.
Pyy protein networkhttps://string-db.org/network/10090.ENSMUSP00000135292Peptide YY(3-36); This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
Cd200r4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135299Cell surface glycoprotein CD200 receptor 4; Involved in the recruitment or surface expression of the TYROBP receptor. Belongs to the CD200R family.
Six3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135312Homeobox protein SIX3; Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a ATTA homeodomain core recognition sequence on these target genes. Dur [...]
Vmn1r4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135323Vomeronasal type-1 receptor.
Gm20708 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135368Predicted gene 20708.
Bnc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135375Zinc finger protein basonuclin-2; Probable transcription factor specific for skin keratinocytes. May play a role in the differentiation of spermatozoa and oocytes.
Esd protein networkhttps://string-db.org/network/10090.ENSMUSP00000135394S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
Glmp protein networkhttps://string-db.org/network/10090.ENSMUSP00000135398Glycosylated lysosomal membrane protein.
Large2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135400LARGE xylosyl- and glucuronyltransferase 2; Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phospho [...]
Mterf1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000135408Transcription termination factor 1b, mitochondrial; Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream o [...]
Zfp169 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135414Zinc finger protein 169.
H2bc18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135427Histone H2B type 2-B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
Tirap protein networkhttps://string-db.org/network/10090.ENSMUSP00000135435Toll/interleukin-1 receptor domain-containing adapter protein; Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the ac [...]
Mrgpra3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135437Mas-related G-protein coupled receptor member A3; Orphan receptor. May be a receptor for RFamide-family neuropeptides such as NPFF and NPAF, which are analgesic in vivo. May regulate nociceptor f [...]
Hmbox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135448Homeobox-containing protein 1; Binds directly to 5'-TTAGGG-3' repeats in telomeric DNA (By similarity). Associates with the telomerase complex at sites of active telomere processing and positivel [...]
Evi5l protein networkhttps://string-db.org/network/10090.ENSMUSP00000135479Ecotropic viral integration site 5-like.
Tmem70 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135483Transmembrane protein 70, mitochondrial; Involved in biogenesis of mitochondrial ATP synthase. Belongs to the TMEM70 family.
Ebf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135500Transcription factor COE2; Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with t [...]
Pbx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135516Pre-B-cell leukemia transcription factor 1; Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcription [...]
Dbndd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135524Dysbindin domain-containing protein 1.
Rpl41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135533Ribosomal protein L41.
Rell2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135556RELT-like protein 2; Induces activation of MAPK14/p38 cascade, when overexpressed. Induces apoptosis, when overexpressed.
Vmn1r7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135571Vomeronasal type-1 receptor.
Pou5f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135597POU domain, class 5, transcription factor 2; Transcription factor that binds preferentially to the octamer motif (5'-ATGTTAAT-3'). May exert a regulatory function in meiotic events that are requi [...]
Cers6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135604Ceramide synthase 6; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward palmitoyl-CoA (hexadecanoyl-CoA; C16:0-CoA) as a [...]
Tcof1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135639Treacle protein; Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. Required for neu [...]
Rgsl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135642Regulator of G-protein-signaling-like 1.
Vmn1r23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135676Vomeronasal type-1 receptor.
Onecut2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135692One cut domain family member 2; Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B (By similarity); Belongs to the CUT homeobox family.
9930021J03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000135696RIKEN cDNA 9930021J03 gene.
Prox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135703Prospero homeobox protein 1; Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number o [...]
Pate13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135716Prostate and testis-expressed 13.
Zfp989 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135720Zinc finger protein 989.
Zfp428 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135750Zinc finger protein 428.
Prss46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135787Serine protease 46; Belongs to the peptidase S1 family.
4932414N04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000135792RIKEN cDNA 4932414N04 gene.
Ccdc190 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135819Coiled-coil domain-containing protein 190.
Gm20695 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135826Predicted gene 20695.
Atpaf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135831ATP synthase mitochondrial F1 complex assembly factor 1; May play an essential role for the assembly of the mitochondrial F1-F0 complex; Belongs to the ATP11 family.
Zbtb25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135853Zinc finger and BTB domain-containing 25.
Ryk protein networkhttps://string-db.org/network/10090.ENSMUSP00000135858Tyrosine-protein kinase RYK; May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establish [...]
Fbxw10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135870F-box/WD repeat-containing protein 10; Probable substrate-recognition component of a SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subseque [...]
Prh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135877Proline-rich protein HaeIII subfamily 1.
Prox2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135881Prospero homeobox protein 2; Transcription regulator. Does not seem to be essential for embryonic development and postnatal survival. Belongs to the Prospero homeodomain family.
Gm4070 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135898Interferon-induced very large GTPase 1.
Gm4307 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135905Predicted gene 4303.
Gm1553 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135907Predicted gene 1553.
Dcdc2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000135913Doublecortin domain-containing 2b.
Mlf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135920Myeloid leukemia factor 2.
C87414-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135923Expressed sequence C87414.
Tmem121b protein networkhttps://string-db.org/network/10090.ENSMUSP00000135924Transmembrane protein 121B; Belongs to the TMEM121 family.
Gfy protein networkhttps://string-db.org/network/10090.ENSMUSP00000135927Golgi-associated olfactory signaling regulator; Required for proper function of the olfactory system. May be involved in establishing the acuity of olfactory sensory signaling.
H2al1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000135929H2A histone family member L1C.
Gm16867 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135940Predicted gene, 16867.
Rpl36-ps4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135946Ribosomal protein L36, pseudogene 4.
Gm13289 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135952Predicted gene 13289.
Gm5096 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135956Predicted gene 5096.
Mgat4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000135959Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C; Glycosyltransferase that participates in the transfer of N- acetylglucosamine (GlcNAc) to the core mannose residues of N- [...]
Gm21897 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135960Predicted gene, 21897.
Gm10142 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135962Predicted gene 10142.
Gm21863 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135963Predicted gene, 21863.
Scgb2a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135964Secretoglobin, family 2A, member 2.
Ccdc162 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135966Coiled-coil domain-containing protein 162.
Dynlt1f protein networkhttps://string-db.org/network/10090.ENSMUSP00000135978Dynein light chain Tctex-type 1F.
Gm13694 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135979Predicted gene 13694.
Esp18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135980Exocrine gland-secreting peptide 18.
LOC108168679 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135981Predicted gene 3893.
Gpr45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135986Probable G-protein coupled receptor 45; Orphan receptor. May play a role in brain function.
Gm17535 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135988Predicted gene, 17535.
Spdye4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000135991Speedy/RINGO cell cycle regulator family, member E4C.
Vmn1r137 protein networkhttps://string-db.org/network/10090.ENSMUSP00000135997Vomeronasal type-1 receptor.
Olfr332 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136008Olfactory receptor.
Gal3st2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000136012Galactose-3-O-sulfotransferase 2; Transfers a sulfate group to the hydroxyl group at C3 of non- reducing beta-galactosyl residues. Acts both on type 1 (Gal-beta-1,3- GlcNAc) and type 2 (Gal-beta- [...]
Ddi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136018DNA-damage inducible protein 2.
Il11ra2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136024Interleukin-11 receptor subunit alpha-2-like.
Gm38394 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136026Zinc finger BED domain-containing protein 6; Transcriptional repressor which binds to the consensus sequence 5'-GCTCGC-3' and represses transcription of IGF2. May also regulate expression of othe [...]
Gyg protein networkhttps://string-db.org/network/10090.ENSMUSP00000136035Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase.
Lhx8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136047LIM/homeobox protein Lhx8; Transcription factor involved in differentiation of certain neurons and mesenchymal cells.
Llgl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136054LLGL scribble cell polarity complex component 2; Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par- 6, which may ensure the correct organization and orientation of bipolar spindles for [...]
Stard9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136055StAR-related lipid transfer protein 9; Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM) (By similarit [...]
Muc3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000136061Mucin 3A, cell surface-associated.
Dnajc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136062DnaJ homolog subfamily C member 4.
Gm19402 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136066Predicted gene, 19402.
Zfp872 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136074Zinc finger protein 872.
Vmn1r130 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136091Vomeronasal 1 receptor 130.
Esp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136092Exocrine gland-secreting peptide 4.
Gm20594 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136098Predicted gene, 20594.
Scgb1b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136099Secretoglobin, family 1B, member 3.
Zfp994 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136105Zinc finger protein 994.
LOC100862115 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136117Predicted gene 3139.
Gm10096 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136137Predicted gene 10096.
Gm16405 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136138Predicted gene 16405.
Vmn1r148 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136142Taste receptor type 2.
Pou3f2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136147POU domain, class 3, transcription factor 2; Transcription factor that plays a key role in neuronal differentiation. Binds preferentially to the recognition sequence which consists of two distinc [...]
Esp16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136148Exocrine gland-secreting peptide 16.
Evi2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000136153Ecotropic viral integration site 2b.
Scgb2b19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136155Secretoglobin, family 2B, member 19.
1700015G11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000136157Coiled-coil domain-containing protein 179.
Edaradd protein networkhttps://string-db.org/network/10090.ENSMUSP00000136158Ectodysplasin-A receptor-associated adapter protein; Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal org [...]
Ankzf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136163Ankyrin repeat and zinc finger domain-containing protein 1; Plays a role in the cellular response to hydrogen peroxide and in the maintenance of mitochondrial integrity under conditions of cellul [...]
Phlpp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136166PH domain leucine-rich repeat-containing protein phosphatase 2; Protein phosphatase involved in regulation of Akt and PKC signaling. Mediates dephosphorylation in the C-terminal domain hydrophobi [...]
Etfbkmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000136167Electron transfer flavoprotein beta subunit lysine methyltransferase; Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria. Thereby, may negativel [...]
4933409K07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000136168annotation not available
Plscr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136181Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry i [...]
Gm28051 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136193Predicted gene, 28051.
Fam240b protein networkhttps://string-db.org/network/10090.ENSMUSP00000136210Family with sequence similarity 240 member B.
Mdn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136222Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.
S100a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136224S100 calcium-binding protein A2.
Gm19668 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136230Predicted gene, 19668.
Gm20825 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136231Predicted gene, 20825.
Vmn1r107 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136232Vomeronasal 1 receptor 107.
Ecsit protein networkhttps://string-db.org/network/10090.ENSMUSP00000136247Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa [...]
Gm49322 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136259Predicted gene, 49322.
Ccl21b protein networkhttps://string-db.org/network/10090.ENSMUSP00000136267C-C motif chemokine 21c.
Tnnt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136278Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin A [...]
Dpf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136280Zinc finger protein DPF3; Muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alter [...]
Gm21904 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136284Serine-rich secreted Y-linked protein.
Gm21866 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136288Predicted gene, 21866.
Zdhhc25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136289Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
Calhm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136302Calcium homeostasis modulator protein 3; Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating volta [...]
Topaz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136304Protein TOPAZ1; Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for no [...]
AF067061 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136309cDNA sequence AF067061.
Ndufa12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136313NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involve [...]
Gm21830 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136315Predicted gene, 21830.
Smlr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136316Small leucine-rich protein 1.
Gm21800 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136321Predicted gene, 21800.
Sgo2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000136323Shugoshin 2B.
Bbip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136324BBSome-interacting protein 1.
Fzd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136328Frizzled-6; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of [...]
Birc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136329Baculoviral IAP repeat-containing protein 6; Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin [...]
Aldh3b3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136334Aldehyde dehydrogenase family 3 member B3; Oxidizes medium and long chain aldehydes into non-toxic fatty acids.
Tmem151b protein networkhttps://string-db.org/network/10090.ENSMUSP00000136337Transmembrane protein 151B.
Srsy protein networkhttps://string-db.org/network/10090.ENSMUSP00000136342Serine-rich, secreted, Y-linked.
E030030I06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000136352RIKEN cDNA E030030I06 gene.
Gm21943 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136356Similar to spermiogenesis specific transcript on the Y 2.
H4f16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136357H4 histone 16.
Fau protein networkhttps://string-db.org/network/10090.ENSMUSP00000136358Ubiquitin-like protein FUBI; Belongs to the ubiquitin family.
Gm6367 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136362Predicted gene 6367.
AA792892-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136368Expressed sequence AA792892.
3110021N24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000136370RIKEN cDNA 3110021N24 gene.
Foxg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136372Forkhead box protein G1; Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telen [...]
Gm21725 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136374Predicted gene, 21725.
Nim1k protein networkhttps://string-db.org/network/10090.ENSMUSP00000136377Serine/threonine-protein kinase NIM1; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Fmo6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136378Dimethylaniline monooxygenase [N-oxide-forming].
Kcnj16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136382Inward rectifier potassium channel 16; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage de [...]
Vmn1r131 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136388Vomeronasal 1 receptor 131.
Mrgpra9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136396MAS-related GPR, member A9; Belongs to the G-protein coupled receptor 1 family.
Itpripl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136409Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2.
Gon7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136425EKC/KEOPS complex subunit GON7; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons [...]
2610528A11Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000136426Protein GPR15L; Chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15. May be a tumor suppressor; together w [...]
Tex44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136430Testis-expressed protein 44.
E030018B13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000136435RIKEN cDNA E030018B13 gene.
Fkbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136438Peptidyl-prolyl cis-trans isomerase FKBP2; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Gm20823 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136451Predicted gene, 20738.
Tbc1d10a protein networkhttps://string-db.org/network/10090.ENSMUSP00000136453TBC1 domain family member 10A; Acts as GTPase-activating protein for RAB27A.
Ddc protein networkhttps://string-db.org/network/10090.ENSMUSP00000136467Aromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine; Belongs t [...]
Phospho2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136471Pyridoxal phosphate phosphatase PHOSPHO2; Phosphatase that has high activity toward pyridoxal 5'- phosphate (PLP). Also active at much lower level toward pyrophosphate, phosphoethanolamine (PEA), [...]
Gm13279 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136472Predicted gene 13279.
Zfp969 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136479Zinc finger protein 969.
Gm7137 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136480Predicted gene 7137.
Plscr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136481Phospholipid scramblase 2; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry [...]
Gm2075 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136486Predicted gene 2075; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ri [...]
Btbd35f6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136491BTB domain-containing 35, family member 6.
Tomm20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136493Mitochondrial import receptor subunit TOM20 homolog; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preprot [...]
Gm11007 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136499Predicted gene 11007.
Slc30a6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136503Zinc transporter 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment.
Zbtb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136507Zinc finger and BTB domain-containing protein 5; May be involved in transcriptional regulation.
Gm960 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136515Type 2 DNA topoisomerase 6 subunit B-like; Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double [...]
Igkv4-54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136516Immunoglobulin kappa chain variable 4-54.
Gm21312 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136519Predicted gene, 20765.
Zfp967 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136521Zinc finger protein 967.
Lmnb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136524Lamin-B2; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope an [...]
Spcs3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136527Signal peptidase complex subunit 3; Component of the microsomal signal peptidase complex which removes signal peptides and other N-terminal peptides from nascent proteins as they are translocated [...]
Ms4a18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136529Membrane-spanning 4-domains, subfamily A, member 18.
Rhox4a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136542Reproductive homeobox 4A2.
March1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136545E3 ubiquitin-protein ligase MARCHF1; E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subse [...]
Gm13693 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136546Predicted gene 13693.
Zfp574 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136547Zinc finger protein 574; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Zfp616 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136549Zinc finger protein 616.
Pbld1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136589Phenazine biosynthesis-like domain-containing protein 1; Belongs to the PhzF family.
Esp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136597Exocrine gland secreted peptide 3.
Gm11168 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136598Predicted gene 11168.
Samd11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136611Sterile alpha motif domain-containing protein 11; May play a role in photoreceptor development.
Btbd35f5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136615Germ cell-less protein-like 2; Possible function in spermatogenesis. Probable substrate- specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequen [...]
Kcne3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136616Potassium voltage-gated channel subfamily E member 3; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates t [...]
Esp34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136619Exocrine gland-secreting peptide 34.
Gpr161 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136621G-protein coupled receptor 161; Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex [...]
Tac2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136622Neurokinin-B; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscle [...]
Gm13277 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136624Predicted gene 13277.
Vmn1r165 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136625Vomeronasal 1 receptor 165.
Gm20821 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136629Predicted gene, 20821.
Gm20738 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136636Predicted gene, 20738.
Ulbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136637UL16-binding protein 1.
Aamp protein networkhttps://string-db.org/network/10090.ENSMUSP00000136644Angio-associated migratory protein.
Tspan8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136645Tetraspanin-8.
Gm21891 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136646Predicted gene, 21891.
Olfr56 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136647Olfactory receptor 56; Odorant receptor. Activated by (+) and (-)-limonene.
Pisd-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136649Phosphatidylserine decarboxylase proenzyme, mitochondrial.
Gm5741 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136655Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta a [...]
Gm3383 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136657Predicted gene 3194.
Gm15093 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136661Predicted gene 15093.
Pate3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136668Prostate and testis expressed protein 3.
Larp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136673La-related protein 1; RNA-binding protein that regulates the translation of specific target mRNA species downstream of the mTORC1 complex, in function of growth signals and nutrient availability. [...]
H2al1f protein networkhttps://string-db.org/network/10090.ENSMUSP00000136695H2A histone family member L1F.
Esp38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136698Exocrine gland secreted peptide 38.
Gm8332 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136709Predicted pseudogene 8332.
Ccdc180 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136714Coiled-coil domain-containing 180.
4931406C07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000136717Ester hydrolase C11orf54 homolog; Exhibits ester hydrolase activity on the substrate p- nitrophenyl acetate.
Aspn protein networkhttps://string-db.org/network/10090.ENSMUSP00000136728Asporin; Binds calcium and plays a role in osteoblast-driven collagen biomineralization activity (By similarity). Critical regulator of TGF- beta in articular cartilage and plays an essential rol [...]
Scgb2b7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136731Secretoglobin, family 2B, member 7.
Gm7694 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136757Predicted gene 7694.
H2al1e protein networkhttps://string-db.org/network/10090.ENSMUSP00000136763Histone H2A; Belongs to the histone H2A family.
Pfn4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136765Profilin-4; Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA) [...]
Esp36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136767Exocrine gland-secreting peptide 36.
Eif4enif1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136768Eukaryotic translation initiation factor 4E transporter; Nucleoplasmic shuttling protein, which inhibits translation initiation. Mediates the nuclear import of EIF4E by a piggy-back mechanism.
1700001F09Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000136772RIKEN cDNA 1700001F09 gene.
Mro protein networkhttps://string-db.org/network/10090.ENSMUSP00000136775Protein maestro.
Ccl21a-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136780C-C motif chemokine 21a.
Rbm31y protein networkhttps://string-db.org/network/10090.ENSMUSP00000136781RNA-binding motif 31, Y-linked.
Ighv6-5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136790Ig heavy chain V-III region J606.
Hist1h2br protein networkhttps://string-db.org/network/10090.ENSMUSP00000136792Histone cluster 1 H2br.
H2al1h protein networkhttps://string-db.org/network/10090.ENSMUSP00000136794H2A histone family member L1H.
Gm21764 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136798Predicted gene, 21764.
G530012D18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000136816RIKEN cDNA G530012D1 gene.
Gm21828 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136822Predicted gene, 21828.
Jdp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136823Jun dimerization protein 2; Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses as [...]
Esp23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136827Exocrine gland-secreting peptide 23.
Gm16367 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136843Predicted gene 16367.
Vmn1r155 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136848Vomeronasal 1 receptor 155.
Gm5926 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136853Predicted gene 5926.
Ldlrad2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136854Low density lipoprotein receptor class A domain containing 2.
Prpf19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136858Pre-mRNA-processing factor 19; [Isoform 1]: Ubiquitin-protein ligase which is a core component of several complexes mainly involved in pre-mRNA splicing and DNA repair. Required for pre-mRNA spli [...]
Fam205a2-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136864Family with sequence similarity 205, member A2.
Maml2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136866Mastermind-like transcriptional coactivator 2.
Gm5426 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136869ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by ele [...]
Gm14322 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136870Predicted gene 14322.
Kbtbd13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136872Kelch repeat and BTB domain-containing protein 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex.
Gm21976 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136875Predicted gene 21976.
Ankrd66 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136879Ankyrin repeat domain 66.
Ighv6-4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136881Immunoglobulin heavy variable V6-4.
Nrg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136884Pro-neuregulin-3, membrane-bound isoform; Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does [...]
Smim18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136891Small integral membrane protein 18.
Amy2a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136894Amylase 2a3.
Fam240a protein networkhttps://string-db.org/network/10090.ENSMUSP00000136900Family with sequence similarity 240 member A.
Gm16430 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136901Predicted gene 16430.
Gm10591 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136903Predicted gene 10591.
Oaz2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136914Ornithine decarboxylase antizyme 2; Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increa [...]
Rad21l protein networkhttps://string-db.org/network/10090.ENSMUSP00000136918Double-strand-break repair protein rad21-like protein 1; Meiosis-specific component of some cohesin complex required during the initial steps of prophase I in male meiosis. Probably required duri [...]
Tmem52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136919Transmembrane protein 52.
ENSMUSP00000136930 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136930annotation not available
Rita1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136946RBPJ-interacting and tubulin-associated protein 1; Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediate [...]
Epn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136950Epsin-2; Plays a role in the formation of clathrin-coated invaginations and endocytosis.
Odaph protein networkhttps://string-db.org/network/10090.ENSMUSP00000136951Odontogenesis-associated phosphoprotein.
Bex3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136952Protein BEX3; May be a signaling adapter molecule involved in p75NTR- mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death; Belongs to the BEX family.
Purb protein networkhttps://string-db.org/network/10090.ENSMUSP00000136957Transcriptional activator protein Pur-beta; Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene [...]
Lig1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136972DNA ligase 1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
Gm10487 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136976Predicted gene 10487.
Mapk9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136977Mitogen-activated protein kinase 9; Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. [...]
Cldn12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136988Claudin-12; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Gm21797 protein networkhttps://string-db.org/network/10090.ENSMUSP00000136989Predicted gene, 21797.
Shisa8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137002Protein shisa-8; May regulate trafficking and current kinetics of AMPA-type glutamate receptor (AMPAR) at synapses.
Cd99 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137004CD99 antigen; Involved in T-cell adhesion processes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site [...]
Krtap22-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137005Keratin-associated protein 22-2.
Gm13696 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137022Predicted gene 13696.
Amy2a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137025Amylase 2a4.
Gm13698 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137026Predicted gene 13698.
H2al1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000137030H2A histone family member L1D.
Igkv4-62 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137031Ig kappa chain V-VI region NQ2-6.1.
Gm5108 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137034Predicted gene 5108.
Pcdhb20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137038Protocadherin beta 20.
H2al1k protein networkhttps://string-db.org/network/10090.ENSMUSP00000137043Histone H2A; Belongs to the histone H2A family.
Elmod2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137044ELMO domain-containing protein 2; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.
Lce1k protein networkhttps://string-db.org/network/10090.ENSMUSP00000137052Late cornified envelope 1K.
Gm3893 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137057Predicted gene 3893.
Samt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137062Spermatogenesis associated multipass transmembrane protein 1.
Zfp653 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137064Zinc finger protein 653; Transcriptional repressor. May repress NR5A1, PPARG, NR1H3, NR4A2, ESR1 and NR3C1 transcriptional activity (By similarity).
Wnt5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000137065Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete r [...]
Btbd35f27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137066BTB domain-containing 35, family member 27.
Sh2d1b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137069SH2 domain-containing protein 1B; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as CD84, SLAMF1, LY9 and CD244. In SLAM signaling se [...]
Ptrhd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137070Putative peptidyl-tRNA hydrolase PTRHD1.
Cpeb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137079Cytoplasmic polyadenylation element-binding protein 1; Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, e [...]
Fsbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000137082Fibrinogen silencer-binding protein; Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via its interaction [...]
Smim22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137083Small integral membrane protein 22.
Gm5294 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137099Predicted gene 5294.
Ccl27-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137101c-C motif chemokine 27-like.
Emc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137103ER membrane protein complex subunit 1.
Faap20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137116Fanconi anemia core complex-associated protein 20; Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. F [...]
BC003965 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137122Protein CCSMST1.
Ryr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137123Ryanodine receptor 1; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction followin [...]
Gm21738 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137127Predicted gene, 21738.
Gm20765 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137128Predicted gene, 20765.
Gm10715 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137129Predicted gene 10715.
Asmt protein networkhttps://string-db.org/network/10090.ENSMUSP00000137135Acetylserotonin O-methyltransferase; Catalyzes the transfer of a methyl group onto N- acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine).
Gm9803 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137140Predicted gene 9803.
Rlbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137143Retinaldehyde-binding protein 1; Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-r [...]
Gm2035 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137146Predicted pseudogene 2035; Belongs to the eIF-1A family.
Ccl21b-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137149Chemokine (C-C motif) ligand 21B (leucine).
Tpbgl protein networkhttps://string-db.org/network/10090.ENSMUSP00000137154Trophoblast glycoprotein-like.
Fam205a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137159Family with sequence similarity 205, member A3.
Gm5128 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137160Predicted gene 5128.
Dynlt1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000137171Dynein light chain Tctex-type 1B.
LOC100041806 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137185PRAME family member 9/15-like.
Smbd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137187Somatomedin B domain-containing 1.
BC024978 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137189cDNA sequence BC024978.
Sox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137203Transcription factor SOX-1; Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins an [...]
Gm9844 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137210Predicted pseudogene 9844.
Gm3448 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137218Predicted gene 3448.
Gm13285 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137222Predicted gene 13285.
Tmsb15b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137225Thymosin beta 15b2.
Gm5849 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137232Predicted gene 5849; Belongs to the S-100 family.
Tmem200c protein networkhttps://string-db.org/network/10090.ENSMUSP00000137246Transmembrane protein 200C.
Noc2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000137253Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53- [...]
Bcap29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137260B-cell receptor-associated protein 29; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8- mediated apoptosis (By [...]
Gm36079 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137272Predicted gene, 21188.
Cypt14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137274Cysteine-rich perinuclear theca 14.
Tbc1d7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137280TBC1 domain family member 7; Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protei [...]
Ccl27b protein networkhttps://string-db.org/network/10090.ENSMUSP00000137284C-C motif chemokine 27; Chemotactic factor that attracts skin-associated memory T- lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migr [...]
Vmn1r138 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137285Vomeronasal 1 receptor 138.
Esp15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137292Exocrine gland-secreting peptide 15.
Gm3106 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137294Predicted gene 3106.
Tdrd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137298Tudor domain-containing protein 5; Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integr [...]
Fam177a protein networkhttps://string-db.org/network/10090.ENSMUSP00000137299Protein FAM177A1; Belongs to the FAM177 family.
Rnaset2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000137303Ribonuclease T2-A; Has ribonuclease activity, with higher activity at acidic pH. May play a role in cellular RNA catabolism. Probably is involved in lysosomal degradation of ribosomal RNA.
Aadacl2fm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137307AADACL2 family member 3.
H1f0 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137309Histone H1.0, N-terminally processed; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The histones H1.0 are found in cells that are in terminal s [...]
Gm10184 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137310Predicted pseudogene 10184.
Gm6803 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137317Predicted gene 6803; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ri [...]
Gm10721 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137330Predicted gene 10721.
Cmtm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137332CKLF-like MARVEL transmembrane domain-containing protein 4; Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune toler [...]
Dapk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137333Death-associated protein kinase 3; Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. Regulates [...]
Gm21833 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137335Predicted gene, 21833.
Rbm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137345RNA-binding protein 4; RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5'-splice site [...]
Tcstv1 protein networkhttps://string-db.org/network/10090.ENSMUSP000001373482-cell-stage, variable group, member 1.
Ccl19-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137353Predicted 2023.
Gm10100 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137358Predicted gene 10100.
Ott protein networkhttps://string-db.org/network/10090.ENSMUSP00000137360Ovary testis transcribed.
Gm21748 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137361Predicted gene, 21748.
Nupr1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000137364Nuclear protein 2; Acts as a transcriptional repressor by inhibiting gene expression at the NUPR1 promoter in a p53/TP53-dependent manner in cancer cells. Involved in the G1 cell cycle arrest, an [...]
Sncaip protein networkhttps://string-db.org/network/10090.ENSMUSP00000137367Synphilin-1.
Btbd35f20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137373BTB domain-containing 35, family member 20.
Pou3f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137374POU domain, class 3, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Thought to be involved in early embryogenesis and neurogenesis.
D430019H16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000137376RIKEN cDNA D430019H16 gene.
Fam177a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137377Family with sequence similarity 177 member A2.
Zfp518b protein networkhttps://string-db.org/network/10090.ENSMUSP00000137381Zinc finger protein 518B; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Fastkd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137385FAST kinase domain-containing protein 5, mitochondrial; Plays an important role in the processing of non-canonical mitochondrial mRNA precursors; Belongs to the FAST kinase family.
Il11ra2-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137393Interleukin-11 receptor subunit alpha-2.
Gm4836 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137394Predicted gene 4836.
Ccl21b-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137398C-C motif chemokine 21b.
Oaz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137400Ornithine decarboxylase antizyme 1; Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increa [...]
Alkal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137420ALK and LTK ligand 1; Ligand for receptor tyrosine kinase LTK and perhaps receptor tyrosine kinase ALK; activation of ALK is reported conflictingly. Belongs to the ALKAL family.
Pol protein networkhttps://string-db.org/network/10090.ENSMUSP00000137421LINE-1 retrotransposable element ORF2 protein; Has a reverse transcriptase activity required for target- primed reverse transcription of the LINE-1 element mRNA, a crucial step in LINE-1 retrotra [...]
Btbd35f29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137428BTB domain-containing 35, family member 29.
Usp34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137430Ubiquitin carboxyl-terminal hydrolase 34; Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activat [...]
Gm21119 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137434Predicted gene, 21119.
Gm21767 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137436Predicted gene, 21767.
Atxn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137439Ataxin-1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along wit [...]
Canx protein networkhttps://string-db.org/network/10090.ENSMUSP00000137440Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER [...]
Rfpl4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000137446Ret finger protein-like 4B.
Ube2u protein networkhttps://string-db.org/network/10090.ENSMUSP00000137472Ubiquitin-conjugating enzyme E2U (putative).
Spin2f protein networkhttps://string-db.org/network/10090.ENSMUSP00000137473Spindlin family, member 2F.
Psap protein networkhttps://string-db.org/network/10090.ENSMUSP00000137476Saposin-B-Val; [Prosaposin]: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated inte [...]
Vmn1r100 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137480Vomeronasal 1 receptor 100.
Scgb2b20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137484Secretoglobin family 2B member 20; Belongs to the secretoglobin family.
Ccer2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137487Coiled-coil glutamate-rich protein 2.
Tmem95 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137492Transmembrane protein 95.
Gm21822 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137501Predicted gene, 21822.
LOC108169010 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137502Protein FAM205A-2-like.
Actr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137503Actin-related protein 3; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 c [...]
Pcgf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137517Polycomb group RING finger protein 2; Transcriptional repressor. Binds specifically to the DNA sequence 5'-GACTNGACT-3'. Has tumor suppressor activity. May play a role in control of cell prolifer [...]
Adgrg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137520Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells [...]
Sulf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137523Extracellular sulfatase Sulf-1; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specif [...]
5730507C01Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000137525RIKEN cDNA 5730507C01 gene.
Rhox5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137526Homeobox protein Rhox5; Transcription factor required for differentiation of embryonic stem cells (ESCs) into primordial germ cells.
Gm11237 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137528Predicted gene 11237.
Ppp2r3d protein networkhttps://string-db.org/network/10090.ENSMUSP00000137530Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit delta; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the local [...]
Samt1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000137533Spermatogenesis associated multipass transmembrane protein 1b.
Slc25a19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137534Mitochondrial thiamine pyrophosphate carrier; Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria.
Ccdc85b protein networkhttps://string-db.org/network/10090.ENSMUSP00000137537Coiled-coil domain-containing protein 85B; Functions as a transcriptional repressor. May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth. May function in a [...]
Gm2007 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137539Predicted gene 2007.
Faiml protein networkhttps://string-db.org/network/10090.ENSMUSP00000137541Fas apoptotic inhibitory molecule-like.
Cfap73 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137554Cilia- and flagella-associated protein 73; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm. Belongs to the CFAP73 family.
Ccl21b-4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137555C-C motif chemokine 21c.
Gm2056 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137563Predicted gene 2056; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ri [...]
Gm15085 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137569Predicted gene 15085.
H2al1g protein networkhttps://string-db.org/network/10090.ENSMUSP00000137575H2A histone family member L1G.
Gm4791 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137580Predicted gene 4791.
Ccl19-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137582C-C motif chemokine.
Col6a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137585Collagen, type VI, alpha 3.
Ccdc191 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137597Coiled-coil domain-containing 191.
Slco1a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137607Solute carrier organic anion transporter family member 1A5; Mediates the Na(+)-independent transport of organic anions such as taurocholate and thyroid hormones; Belongs to the organo anion trans [...]
Ttc28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137609Tetratricopeptide repeat protein 28; During mitosis, may be involved in the condensation of spindle midzone microtubules, leading to the formation of midbody.
Polr3d protein networkhttps://string-db.org/network/10090.ENSMUSP00000137614DNA-directed RNA polymerase III subunit RPC4; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific componen [...]
Ankrd44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137616Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B; Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein su [...]
Gm13278 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137618Predicted gene 13278.
Pet100 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137626Protein PET100 homolog, mitochondrial; Belongs to the PET100 family.
Nlrc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137628Protein NLRC3; Negative regulator of the innate immune response. Attenuates signaling pathways activated by Toll-like receptors (TLRs) and the DNA sensor STING/TMEM173 in response to pathogen-ass [...]
Gm3194 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137641Predicted gene 3194.
Ascl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137650Achaete-scute family bHLH transcription factor 4.
Foxf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137662Forkhead box protein F1; Probable transcription activator for a number of lung- specific genes.
Jsrp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137666Junctional sarcoplasmic reticulum protein 1; Involved in skeletal muscle excitation/contraction coupling (EC), probably acting as a regulator of the voltage-sensitive calcium channel CACNA1S (By [...]
Ksr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137670Kinase suppressor of Ras 2; Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low effi [...]
Gm6614 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137696Solute carrier organic anion transporter family member.
B020031M17Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000137705RIKEN cDNA B020031M17 gene.
Gm21304 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137711Predicted gene, 21304.
Usp35 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137726Ubiquitin-specific peptidase 35; Belongs to the peptidase C19 family.
Gm26602 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137730Predicted gene, 26602.
Foxl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137732Forkhead box protein L1; Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 [...]
Fam47c protein networkhttps://string-db.org/network/10090.ENSMUSP00000137737Family with sequence similarity 47, member A.
Nudt22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137738Uridine diphosphate glucose pyrophosphatase NUDT22; Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and UDP-galactose to galactose 1-phosphate and UMP. Preferred substrate is UDP-glucose.
Ascl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137746Achaete-scute family bHLH transcription factor 5.
Rhbdd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137770Rhomboid-related protein 4; Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and ju [...]
Gm10267 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137781Predicted gene 10267.
Gm27021 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137785Predicted gene, 27021.
Gm4340 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137824Predicted gene 4340.
Crtam protein networkhttps://string-db.org/network/10090.ENSMUSP00000137837Cytotoxic and regulatory T-cell molecule; Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cel [...]
4930444P10Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000137853RIKEN cDNA 4930444P10 gene.
Dmxl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137871DmX-like protein 1.
Ndfip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137875NEDD4 family-interacting protein 2; Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability o [...]
Gm20909 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137876Similar to spermiogenesis specific transcript on the Y 2.
Apol11b protein networkhttps://string-db.org/network/10090.ENSMUSP00000137890Apolipoprotein L 11b.
Gsg1l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137895GSG1-like 2.
Enho protein networkhttps://string-db.org/network/10090.ENSMUSP00000137902Adropin; Involved in the regulation of glucose homeostasis and lipid metabolism.
Zfp273 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137903Regulator of sex-limitation candidate 1.
Car1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137926Carbonic anhydrase 1; Reversible hydration of carbon dioxide.
Zfp748 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137928Zinc finger protein 748.
Gm8764 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137930Predicted gene 8764.
Agrn protein networkhttps://string-db.org/network/10090.ENSMUSP00000137931Agrin C-terminal 110 kDa subunit; [Isoform 1]: heparan sulfate basal lamina glycoprotein that plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ) and dir [...]
Ssh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137933Protein phosphatase Slingshot homolog 2; Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequ [...]
Gm6763 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137957Predicted gene 6763.
Tnfsf12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137972Tumor necrosis factor ligand superfamily member 12, membrane form; Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. [...]
Tnfsfm13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000137973Tumor necrosis factor (ligand) superfamily, membrane-bound member 13; Belongs to the tumor necrosis factor family.
Cxxc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138000CXXC-type zinc finger protein 4; Acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1. Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) [...]
Tdpoz1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138008TD and POZ domain-containing protein 1.
Tdpoz9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138015TD and POZ domain-containing protein 1-like; Belongs to the Tdpoz family.
Cox4i1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138019Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylatio [...]
Gm20865 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138020Predicted gene, 20865.
Raet1e protein networkhttps://string-db.org/network/10090.ENSMUSP00000138022Retinoic acid early-inducible protein 1-epsilon; Acts as a ligand for KLRK1; Belongs to the NKG2D ligand family.
Snx29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138025Sorting nexin-29.
Gm2916 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138028Predicted gene 2916.
Olfr884 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138035Olfactory receptor Olfr884.
Rd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138049Protein RD3; Plays a critical role in the regulation of enzymes involved in nucleotide cycle in photoreceptors. Inhibits the basal catalytic activity and the GCAP- stimulated activity of GUCY2E a [...]
Gm20854 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138074Predicted gene, 20854.
Fam193a protein networkhttps://string-db.org/network/10090.ENSMUSP00000138082Protein FAM193A; Belongs to the FAM193 family.
Zfp87 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138087Zinc finger protein 87.
Ccdc154 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138090Coiled-coil domain-containing protein 154.
Sstr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138101Somatostatin receptor type 2; Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates [...]
Rassf10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138103Ras association domain-containing protein 10; Plays an important role in regulating embryonic neurogenesis.
Ccdc166 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138115Coiled-coil domain-containing 166.
Gm26938 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138120Predicted gene, 26938.
H2ab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138181Histone H2A; Belongs to the histone H2A family.
Baiap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138188BAI1-associated protein 3; Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endos [...]
Ano4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138193Anoctamin-4; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide. Does not exhibit calcium- activated chloride channel [...]
H2ab3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138211Histone H2A; Belongs to the histone H2A family.
Iqschfp protein networkhttps://string-db.org/network/10090.ENSMUSP00000138212IQCJ-SCHIP1 readthrough transcript protein; May play a role in action potential conduction in myelinated cells through the organization of molecular complexes at nodes of Ranvier and axon initial [...]
4933405O20Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000138215Probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial; Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) [...]
Sbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000138219Prostatic spermine-binding protein; This protein seems to be functional equivalent to rat prostatic spermine-binding protein, which is involved in polyamine binding.
Btbd19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138230BTB (POZ) domain-containing 19.
Xpnpep1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138250Xaa-Pro aminopeptidase 1; Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro (By similarity).
Xcr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138255Chemokine XC receptor 1; Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level. Receptor for XCL1/Lymphotactin (Probable).
H2ab2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138278Histone H2A; Belongs to the histone H2A family.
Gm27027 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138281Predicted gene, 27027.
Dclre1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000138290DNA cross-link repair 1A protein; May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle p [...]
Sox12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138293Transcription factor SOX-12; Binds to the sequence 5'-AACAAT-3'.
Zfp386 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138305Zinc finger protein 386 (Kruppel-like) isoform a.
Dst protein networkhttps://string-db.org/network/10090.ENSMUSP00000138308Dystonin; Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the ac [...]
Ppfia1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138312Ppfia1 protein.
Ank3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138326Ankyrin-3; Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments (By similarit [...]
Raet1d protein networkhttps://string-db.org/network/10090.ENSMUSP00000138328Retinoic acid early-inducible protein 1-delta; Acts as a ligand for KLRK1.
Rpl9-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138342Ribosomal protein L9, pseudogene 1.
Ptprc protein networkhttps://string-db.org/network/10090.ENSMUSP00000138350Receptor-type tyrosine-protein phosphatase C; Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation [...]
Sowahc protein networkhttps://string-db.org/network/10090.ENSMUSP00000138351Ankyrin repeat domain-containing protein SOWAHC; Belongs to the SOWAH family.
Arl14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138370ADP-ribosylation factor-like protein 14; GTPase that recruits MYO1E to MHC class II-containing vesicles via the effector protein ARL14EP and hence controls the movement of these vesicles along th [...]
Kat6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000138377Histone acetyltransferase KAT6B; Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2- dependent transcriptional activatio [...]
Rbm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138379RNA-binding protein 5; Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to t [...]
Mzf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138387Myeloid zinc finger 1.
Tktl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138388Transketolase-like protein 2; Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activit [...]
Olfr67 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138389Olfactory receptor.
Gm3839 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138396Glyceraldehyde-3-phosphate dehydrogenase.
Hnrnpr protein networkhttps://string-db.org/network/10090.ENSMUSP00000138399Heterogeneous nuclear ribonucleoprotein R.
Rbm6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138400RNA-binding motif protein 6.
Cul9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138418Cullin-9; Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynami [...]
Prrc2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000138433Protein PRRC2C.
Scgb2b17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138446Secretoglobin, family 2B, member 15.
Dennd2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000138462DENN domain-containing protein 2D; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins int [...]
Atp13a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138479Probable cation-transporting ATPase 13A4.
Sbk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138504Serine/threonine-protein kinase SBK2; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.
Bin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138523Bridging integrator 2; Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulat [...]
Rnf113a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138536Ring finger protein 113A2.
Samd15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138551Sterile alpha motif domain-containing protein 15.
Rnf4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138555E3 ubiquitin-protein ligase RNF4; E3 ubiquitin-protein ligase which binds polysumoylated chains covalently attached to proteins and mediates 'Lys-6'-, 'Lys-11'-, 'Lys- 48'- and 'Lys-63'-linked po [...]
Plekha7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138575Pleckstrin homology domain-containing family A member 7; Required for zonula adherens biogenesis and maintenance. Acts via its interaction with CAMSAP3, which anchors microtubules at their minus- [...]
Rpf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138581Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 [...]
Arhgap12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138585Rho GTPase-activating protein 12; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Cacng8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138618Voltage-dependent calcium channel gamma-8 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Regulates the trafficking and gating properties [...]
Cacng6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138622Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG sub [...]
Gapdhs protein networkhttps://string-db.org/network/10090.ENSMUSP00000138634Glyceraldehyde-3-phosphate dehydrogenase, testis-specific; May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the sp [...]
Efcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138649EF-hand and coiled-coil domain-containing protein 1.
Anks1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000138655Ankyrin repeat and sterile alpha motif domain-containing protein 1B; Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells.
Pdf protein networkhttps://string-db.org/network/10090.ENSMUSP00000138676Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family.
Scgb2b12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138687Secretoglobin, family 2B, member 12.
Rsrc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138691Arginine/serine-rich coiled-coil protein 2; Belongs to the RSRC2 family.
Smim1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138692Small integral membrane protein 1; Regulator of red blood cell formation.
Sftpb protein networkhttps://string-db.org/network/10090.ENSMUSP00000138695Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air sp [...]
Cox6b2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138709Cytochrome c oxidase subunit 6B2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chai [...]
Sept14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138729Septin-14; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Slc8a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138735Sodium/calcium exchanger 3; Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca [...]
Ank2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138753Ankyrin-2; Plays an essential role in the localization and membrane stabilization of ion transporters and ion channels in several cell types, including cardiomyocytes, as well as in striated musc [...]
Prss56 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138773Serine protease 56; Serine protease required during eye development.
Scgb2b15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138802Secretoglobin, family 2B, member 15.
Tlr11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138814Toll-like receptor 11; Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response [...]
Tcf24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138827Transcription factor 24.
Rhox3f protein networkhttps://string-db.org/network/10090.ENSMUSP00000138833Reproductive homeobox 3F.
Il6st protein networkhttps://string-db.org/network/10090.ENSMUSP00000138836Interleukin-6 receptor subunit beta; Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding o [...]
Spata17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138855Spermatogenesis-associated protein 17.
Gm15013 protein networkhttps://string-db.org/network/10090.ENSMUSP0000013888440S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.
Obox8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138898Oocyte-specific homeobox 8.
Tmem196 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138921Transmembrane protein 196.
Gm11214 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138923Predicted gene 11214.
Obox7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138932Oocyte-specific homeobox 7.
Entpd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138944Ectonucleoside triphosphate diphosphohydrolase 4; Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. Belongs to the GDA1/CD39 [...]
Gvin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138950Interferon-induced very large GTPase 1.
Gm12728 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138955Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophi [...]
Csmd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138958CUB and Sushi multiple domains 2.
Gm14214 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138961Predicted gene 14214.
Gm17190 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138965Predicted gene 17190.
Triqk protein networkhttps://string-db.org/network/10090.ENSMUSP00000138966Triple QxxK/R motif-containing protein; May play a role in cell growth and maintenance of cell morphology; Belongs to the TRIQK family.
Mphosph9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000138982M-phase phosphoprotein 9.
Gm28036 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139010Predicted gene, 28036.
Doxl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139012Amine oxidase; Belongs to the copper/topaquinone oxidase family.
Trps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139017Zinc finger transcription factor Trps1; Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate [...]
Tmem185b protein networkhttps://string-db.org/network/10090.ENSMUSP00000139021Transmembrane protein 185B.
Tex9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139026Testis-expressed protein 9.
Unc13c protein networkhttps://string-db.org/network/10090.ENSMUSP00000139027Protein unc-13 homolog C; May play a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. May be involved in the regulation of synaptic transmi [...]
Mroh6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139029Maestro heat-like repeat family member 6.
Erc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139031ELKS/Rab6-interacting/CAST family member 1; Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex (By similarity). May be involved in the organization of the [...]
Wnk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139037Serine/threonine-protein kinase WNK3; Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an ac [...]
Pet117 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139043Protein PET117 homolog, mitochondrial.
Nav2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139045Neuron navigator 2.
Btg1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000139062BTG anti-proliferation factor 1B.
Gm15294 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139065Predicted gene 15294.
Olfr1162 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139068Olfactory receptor.
Dexi protein networkhttps://string-db.org/network/10090.ENSMUSP00000139108Dexamethasone-induced protein; Belongs to the DEXI family.
Lzts1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139117Leucine zipper putative tumor suppressor 1; Involved in the regulation of cell growth. May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle a [...]
Gm5269 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139129Predicted gene 5269.
Slfn14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139132C-terminally truncated SLFN14 endoribonuclease; [Protein SLFN14]: Shows no ribosome-associated and endoribonuclease activities.
Plac9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000139134Placenta specific 9b.
Pin1rt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139143Peptidyl-prolyl cis-trans isomerase.
Efcab12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139144EF-hand calcium-binding domain 12.
Smim5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139148Small integral membrane protein 5.
Atf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139181Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in [...]
Gm12117 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139186Predicted gene 12117.
Ccpg1os protein networkhttps://string-db.org/network/10090.ENSMUSP00000139187Cell cycle progression 1, opposite strand.
Entpd4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000139202Ectonucleoside triphosphate diphosphohydrolase 4B.
Meis1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139219Homeobox protein Meis1; Acts as a transcriptional regulator of PAX6. Also acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineag [...]
Lrrc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139226Leucine-rich repeat-containing protein 1.
Cphx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139237Cytoplasmic polyadenylated homeobox 1.
Kctd12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139261BTB/POZ domain-containing protein KCTD12; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter [...]
Gm17087 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139264Predicted gene 17087.
Rgs21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139265Regulator of G-protein signalling 21.
Gm27179 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139267Predicted gene 27179.
Pigb protein networkhttps://string-db.org/network/10090.ENSMUSP00000139269GPI mannosyltransferase 3; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2- GlcN-acyl-PI during GPI precursor asse [...]
Ism1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139280Isthmin-1; Acts as an angiogenesis inhibitor. Belongs to the isthmin family.
Rnf138rt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139291Ring finger protein 138, retrogene 1.
Cphx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139300Cytoplasmic polyadenylated homeobox 3.
Gm11983 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139301Predicted gene 11983.
Rab27a protein networkhttps://string-db.org/network/10090.ENSMUSP00000139310Ras-related protein Rab-27A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis [...]
Aspa protein networkhttps://string-db.org/network/10090.ENSMUSP00000139318Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant [...]
Calm5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139342Skin calmodulin-related protein 2.
Tac1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139347C-terminal-flanking peptide; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) man [...]
Kcnn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139350Small conductance calcium-activated potassium channel protein 2; Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolariza [...]
Fam83b protein networkhttps://string-db.org/network/10090.ENSMUSP00000139354Protein FAM83B; Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR s [...]
Nlrp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139357NACHT, LRR and PYD domains-containing protein 6; As the sensor component of the NLRP6 inflammasome, plays a crucial role in innate immunity and inflammation. In response to yet unidentified signa [...]
Kif7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139359Kinesin-like protein KIF7; Essential for hedgehog signaling regulation: acts as both a negative and positive regulator of sonic hedgehog (Shh) and Indian hedgehog (Ihh) pathways, acting downstrea [...]
Tcf12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139365Transcription factor 12; Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').
Hnrnpll protein networkhttps://string-db.org/network/10090.ENSMUSP00000139372Heterogeneous nuclear ribonucleoprotein L-like; RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for al [...]
C1rb protein networkhttps://string-db.org/network/10090.ENSMUSP00000139376Complement C1r-B subcomponent heavy chain; C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
Htr1b protein networkhttps://string-db.org/network/10090.ENSMUSP000001393895-hydroxytryptamine receptor 1B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding cau [...]
Lrcol1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139397Leucine-rich colipase-like protein 1.
Col6a5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139398Collagen alpha-5(VI) chain; Collagen VI acts as a cell-binding protein.
Gm21209 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139400Predicted gene, 20843.
Usp27x protein networkhttps://string-db.org/network/10090.ENSMUSP00000139402Ubiquitin carboxyl-terminal hydrolase 27; Deubiquitinase that can reduce the levels of BCL2L11/BIM ubiquitination and stabilize BCL2L11 in response to the RAF-MAPK- degradation signal. By acting [...]
Il19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139406Interleukin-19; May play some important roles in inflammatory responses. Up- regulates IL-6 and TNF-alpha and induces apoptosis. Belongs to the IL-10 family.
Gm21854 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139409Predicted gene, 21854.
Dydc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139412DPY30 domain-containing protein 1; Plays a crucial role during acrosome biogenesis.
Flacc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139420Flagellum-associated coiled-coil domain-containing protein 1.
Gm21244 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139421Predicted gene, 20826.
Pik3r4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139427Phosphoinositide 3-kinase regulatory subunit 4; Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a [...]
Gm21778 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139442Predicted gene, 21778.
Smim10l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139452Small integral membrane protein 10-like 1.
Gm20869 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139478Predicted gene, 20814.
Eloc protein networkhttps://string-db.org/network/10090.ENSMUSP00000139480Elongin-C; SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A [...]
Kcna6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139481Potassium voltage-gated channel subfamily A member 6; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective [...]
Gm20747 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139491Predicted gene, 20747.
Ssty2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139505Spermiogenesis-specific transcript on the Y 2.
Gm28079 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139506Predicted gene, 33815.
Cep57l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139509Centrosomal protein CEP57L1; Centrosomal protein which may be required for microtubule attachment to centrosomes.
Gm29554 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139522Predicted gene 29554.
Gm29276 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139523Predicted gene 29276.
Fam227a protein networkhttps://string-db.org/network/10090.ENSMUSP00000139524Family with sequence similarity 227, member A.
Gm21677 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139527Predicted gene, 21677.
Twist2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139531Twist-related protein 2; Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of [...]
Gm21861 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139535RIKEN cDNA 1700040F15 gene.
Gm20772 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139540Predicted gene, 20737.
Krtap10-4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139550Keratin associated protein 10-4.
Cxcr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139555C-X-C chemokine receptor type 1; Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is [...]
Krtap16-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139557Keratin-associated protein 16-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Ly6c1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139559Lymphocyte antigen 6C1.
Mag protein networkhttps://string-db.org/network/10090.ENSMUSP00000139564Myelin-associated glycoprotein; Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid- containing gangliosides and to the glycoprot [...]
Scgb1b15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139565Secretoglobin, family 1B, member 15.
Rgs6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139566Regulator of G-protein signaling 6; Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby dr [...]
Slc25a13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139571Calcium-binding mitochondrial carrier protein Aralar2; Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartat [...]
Ldhal6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000139572L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
Gm21310 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139580Predicted gene, 21310.
Zfp995 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139581Zinc finger protein 995.
H2al1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000139582Histone H2A; Belongs to the histone H2A family.
Gm4312 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139588Predicted gene 4301.
Prr30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139590Proline-rich protein 30.
Zfy2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139591Zinc finger Y-chromosomal protein 2; Probable transcriptional activator. Binds to the consensus sequence 5'-AGGCCY-3' (By similarity).
Scgb1b12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139594Secretoglobin, family 1B, member 12.
Gm20896 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139596Predicted gene, 20896.
Myrf protein networkhttps://string-db.org/network/10090.ENSMUSP00000139601Myelin regulatory factor, C-terminal; [Myelin regulatory factor]: Constitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory fact [...]
Gm28510 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139602Predicted gene 28510.
Gm6205 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139603Predicted gene 6205.
Gm20737 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139604Predicted gene, 20737.
Phf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139610PHD finger protein 3.
Gm28919 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139611Predicted gene 28919.
Gm20924 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139614Predicted gene, 20924.
Gm21719 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139615Predicted gene, 21719.
Gm29564 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139621Predicted gene, 21760.
Scgb1b17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139627Secretoglobin, family 1B, member 17.
Tet3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139630Methylcytosine dioxygenase TET3; Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenet [...]
Pign protein networkhttps://string-db.org/network/10090.ENSMUSP00000139638GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4- [...]
Atg9a protein networkhttps://string-db.org/network/10090.ENSMUSP00000139641Autophagy-related protein 9A; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore [...]
Gm20929 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139649Predicted gene, 20929.
Spcs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139654Signal peptidase complex subunit 1; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endopla [...]
Gm21708 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139659Predicted gene, 21708.
Krtap6-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139661Keratin-associated protein 6-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
H3c11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139663H3 clustered histone 11.
Gm20795 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139666Predicted gene, 20795.
Trpc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139672Short transient receptor potential channel 1; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger s [...]
Bckdhb protein networkhttps://string-db.org/network/10090.ENSMUSP000001396842-oxoisovalerate dehydrogenase subunit beta, mitochondrial; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It cont [...]
Gm20837 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139688Predicted gene, 20837.
Lbhd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139692LBH domain-containing 1.
Gm28961 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139697Predicted gene 28961.
Kif14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139698Kinesin-like protein KIF14; Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity. Plays a role in many processes lik [...]
Myb protein networkhttps://string-db.org/network/10090.ENSMUSP00000139699Transcriptional activator Myb; Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and [...]
Scgb2b18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139701Secretoglobin, family 2B, member 18.
Gm9745 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139705Predicted gene 9745.
Gm20822 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139707Predicted gene, 20822.
Gm20867 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139713Predicted gene, 20816.
Cyp4a29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139717Cytochrome P450, family 4, subfamily a, polypeptide 29; Belongs to the cytochrome P450 family.
Gm20870 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139722Predicted gene, 20870.
Krtap5-1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139752Keratin-associated protein 5-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated protein (KRTAP), which a [...]
Auts2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139759Autism susceptibility gene 2 protein homolog; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of ma [...]
Gm20828 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139764Predicted gene, 20828.
Gm29644 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139765Predicted gene 29644.
Gm13283 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139768Predicted gene 13283.
Fam122c protein networkhttps://string-db.org/network/10090.ENSMUSP00000139776Family with sequence similarity 122, member C.
Gm6358 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139779Predicted gene 6358.
Gm21693 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139784Predicted gene, 21693.
Gm28553 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139793Predicted gene, 20817.
Gm21117 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139807Predicted gene, 21117.
Gm20914 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139808Predicted gene, 20914.
Dhx9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139825ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA re [...]
Slc18a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139829Vesicular acetylcholine transporter; Involved in acetylcholine transport into synaptic vesicles. Belongs to the major facilitator superfamily. Vesicular transporter family.
Skint2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139831Selection and upkeep of intraepithelial T-cells protein 2; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus.
Gm7073 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139835Predicted gene 7073.
Gm20812 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139838Predicted gene, 20812.
Gm3604 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139845Zinc finger protein.
Gm20820 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139858Predicted gene 28870.
Plin4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139859Perilipin-4; May play a role in triacylglycerol packaging into adipocytes. May function as a coat protein involved in the biogenesis of lipid droplets.
Sytl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139865Synaptotagmin-like protein 2; Isoform 11 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. Required for cytotoxic granule docking at the immunolog [...]
Gm20736 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139870Predicted gene, 20736.
Gm21258 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139882Predicted gene, 20736.
Ssty1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139883Y-linked testis-specific protein 1; Belongs to the SPIN/STSY family.
Prm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139898Protamine-2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.
Prkag3 protein networkhttps://string-db.org/network/10090.ENSMUSP000001399095'-AMP-activated protein kinase subunit gamma-3; AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energ [...]
Tmem81 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139911Transmembrane protein 81.
Gm29582 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139915Predicted gene 28490.
Neil1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139917Endonuclease 8-like 1; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for [...]
Olfr1228 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139920Olfactory receptor.
Scgb1b10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139939Secretoglobin, family 1B, member 10.
Serpina1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000139941Alpha-1-antitrypsin 1-2; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Belongs to the serpin family.
Glce protein networkhttps://string-db.org/network/10090.ENSMUSP00000139949D-glucuronyl C5-epimerase; Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is [...]
Gm21874 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139963Predicted gene, 21874.
Gm20877 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139965Predicted gene, 20877.
Gm4450 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139967Predicted gene 4450.
Gm29289 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139969Predicted gene 29289.
Krtap14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139983Keratin-associated protein 14; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which a [...]
Gm21721 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139987Predicted gene, 21721.
Gm28827 protein networkhttps://string-db.org/network/10090.ENSMUSP00000139992Predicted gene 28827.
Msh3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140002DNA mismatch repair protein Msh3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating [...]
Gm20918 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140003Predicted gene, 20918.
Gm28171 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140005Predicted gene 28171.
Gm21858 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140010Predicted gene, 21858.
Btbd35f23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140013BTB domain-containing 35, family member 23.
Gm10662 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140018Predicted gene 10662; Belongs to the protein kinase superfamily.
Serpina3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000140024Serine protease inhibitor A3A; Belongs to the serpin family.
Naa60 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140031N-alpha-acetyltransferase 60; N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini fac [...]
Srcap protein networkhttps://string-db.org/network/10090.ENSMUSP00000140036Snf2-related CREBBP activator protein.
Birc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140049Baculoviral IAP repeat-containing protein 2; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase sig [...]
Gm20937 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140064Predicted gene, 20937.
Gm20888 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140067Predicted gene, 20888.
Dvl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140073Segment polarity protein dishevelled homolog DVL-2; Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling [...]
Gm29110 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140088Predicted gene 29110.
Misp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140089MISP family member 3.
Gm29666 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140100Predicted gene 29666.
Gm20843 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140105Predicted gene, 20843.
Uchl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140106Ubiquitin carboxyl-terminal hydrolase isozyme L5; Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of th [...]
Usp40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140107Ubiquitin carboxyl-terminal hydrolase 40; Belongs to the peptidase C19 family.
Apbb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140116Amyloid-beta A4 precursor protein-binding family B member 1; Adapter protein that forms a transcriptionally active complex with the gamma-secretase-derived amyloid precursor protein (APP) intrace [...]
Pgr protein networkhttps://string-db.org/network/10090.ENSMUSP00000140124Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissue [...]
Neu4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140127Sialidase-4; May function in lysosomal catabolism of sialylated glycoconjugates. Has sialidase activity towards synthetic substrates, such as 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic [...]
2310034C09Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000140130RIKEN cDNA 2310034C09 gene.
Chrm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140131Muscarinic acetylcholine receptor M3; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modu [...]
Gm20873 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140138Predicted gene, 20873.
Hivep2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140150Transcription factor HIVEP2; Specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In ad [...]
Gstp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140159Glutathione S-transferase pi 3.
Gm21317 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140162Predicted gene, 21317.
Clasp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140167CLIP-associating protein 1; Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating fr [...]
Agfg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140170Arf-GAP domain and FG repeat-containing protein 1; Required for vesicle docking or fusion during acrosome biogenesis. May play a role in RNA trafficking or localization.
Ly6g protein networkhttps://string-db.org/network/10090.ENSMUSP00000140173Lymphocyte antigen 6G.
Gnas protein networkhttps://string-db.org/network/10090.ENSMUSP00000140174Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protei [...]
Rhof protein networkhttps://string-db.org/network/10090.ENSMUSP00000140177Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich su [...]
Lrit3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140184Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3; Plays a role in the synapse formation and synaptic transmission between cone photoreceptor cells and [...]
Lemd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140193LEM domain-containing protein 1.
Mdfic protein networkhttps://string-db.org/network/10090.ENSMUSP00000140208MyoD family inhibitor domain-containing protein; Acts as a transcriptional activator or repressor. Inhibits the transcriptional activation of Zic family proteins ZIC1, ZIC2 and ZIC3. Retains nucl [...]
B020011L13Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000140211RIKEN cDNA B020011L13 gene.
Scgb1b11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140214Secretoglobin, family 1B, member 11.
Gm20890 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140218Predicted gene, 20890.
Kirrel3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140219Processed kin of IRRE-like protein 3; Synaptic adhesion molecule required for the formation of target-specific synapses. Required for formation of target-specific synapses at hippocampal mossy fi [...]
Gm21477 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140238Predicted gene, 21477.
Gm28102 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140242Predicted gene 28102.
Taf9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140244TATA-box binding protein associated factor 9.
Krtap6-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140246Keratin-associated protein 6-3.
Gm28891 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140248Predicted gene 28891.
Nop58 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140250Nucleolar protein 58; Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of [...]
Ash1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000140251Histone-lysine N-methyltransferase ASH1L; Histone methyltransferase specifically trimethylating 'Lys- 36' of histone H3 forming H3K36me3 (By similarity). Also monomethylates 'Lys-9' of histone H3 [...]
1700040F15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000140263RIKEN cDNA 1700040F15 gene.
Smpx protein networkhttps://string-db.org/network/10090.ENSMUSP00000140268Small muscular protein; Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair; Belongs to the S [...]
Gsdmc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140269Gasdermin-C4; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family.
Gsdmc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140272Gasdermin-C3; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family.
Abi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140274Abl interactor 2; Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 t [...]
Kcnma1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140275Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated [...]
Zfp709 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140285Zinc finger protein 709.
Ly6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000140287Lymphocyte antigen 6A-2/6E-1; T-cell activation.
Krtap28-13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140288Keratin-associated protein 28-13.
Gm21698 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140294Predicted gene, 21698.
Gm21812 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140302Predicted gene, 21812.
Gm20906 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140305Predicted gene, 20906.
Gm4567 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140310Predicted gene, EG381936; Belongs to the protein kinase superfamily.
Ktn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140324Kinectin; Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin (By similarity).
Anapc13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140325Anaphase-promoting complex subunit 13; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the [...]
Gm20816 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140326Predicted gene, 20816.
Prrxl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140337Dorsal root ganglia homeobox protein; Transcription factor required for the formation of correct projections from nociceptive sensory neurons to the dorsal horn of the spinal cord and normal perc [...]
Sly protein networkhttps://string-db.org/network/10090.ENSMUSP00000140340Sycp3 like Y-linked.
1700088E04Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000140347UPF0193 protein EVG1 homolog; Belongs to the UPF0193 (EVG1) family.
Ly6g6g protein networkhttps://string-db.org/network/10090.ENSMUSP00000140350Lymphocyte antigen 6 complex, locus G6G.
Mturn protein networkhttps://string-db.org/network/10090.ENSMUSP00000140358Maturin; Promotes megakaryocyte differentiation by enhancing ERK and JNK signaling as well as up-regulating RUNX1 and FLI1 expression. Represses NF-kappa-B transcriptional activity by inhibiting [...]
Gm28363 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140366Predicted gene 28363.
Scgb3a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140375Secretoglobin family 3A member 2; Secreted cytokine-like protein (By similarity). Binds to the scavenger receptor MARCO (By similarity). Can also bind to pathogens including the Gram-positive bac [...]
2410004P03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000140390RIKEN cDNA 2410004P03 gene.
Begain protein networkhttps://string-db.org/network/10090.ENSMUSP00000140393Brain-enriched guanylate kinase-associated protein; May sustain the structure of the postsynaptic density (PSD).
H3c10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140394H3 clustered histone 10.
Gm20852 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140403Predicted gene, 20852.
Ncf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140404Neutrophil cytosol factor 2; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
Gm49380 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140405Predicted gene, 49380.
Spock1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140409Testican-1; May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system.
Atp5g2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140414ATP synthase F(0) complex subunit C2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the [...]
Cysrt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140416Cysteine-rich tail protein 1; Belongs to the CYSRT1 family.
Dnah7c protein networkhttps://string-db.org/network/10090.ENSMUSP00000140430Dynein, axonemal, heavy chain 7C.
Gm21095 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140431Predicted gene, 21095.
Ano7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140438Anoctamin-7; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide. Does not exhibit calcium- activated chloride channel [...]
Gm10668 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140440Predicted gene 10668.
Gm20379 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140453Predicted gene, 20379.
Rd3l protein networkhttps://string-db.org/network/10090.ENSMUSP00000140454Retinal degeneration 3-like.
Nkain2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140463Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2; Belongs to the NKAIN family.
Prob1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140465Proline-rich basic protein 1.
Gm21118 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140466Predicted gene, 21118.
Gm20931 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140468Predicted gene, 20931.
Scgb2b11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140470Secretoglobin, family 2B, member 11.
Gm21173 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140477Predicted gene, 21173.
Mei1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140479Meiosis inhibitor protein 1; Required for normal meiotic chromosome synapsis. May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes.
Muc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140483Mucin-6; May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an im [...]
Gsdmc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140487Gasdermin-C2; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family.
Gm20826 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140488Predicted gene, 20826.
Gm20855 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140500Predicted gene, 20855.
Gm20917 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140501Predicted gene, 20917.
Lce1j protein networkhttps://string-db.org/network/10090.ENSMUSP00000140507Late cornified envelope 1J.
Apela protein networkhttps://string-db.org/network/10090.ENSMUSP00000140510Apelin receptor early endogenous ligand; Endogenous ligand for the apelin receptor (APLNR) (By similarity). Hormone required for mesendodermal differentiation, blood vessels formation and heart m [...]
Gm4064 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140512Predicted gene 4064.
Gm21488 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140532Predicted gene, 21488.
Erbin protein networkhttps://string-db.org/network/10090.ENSMUSP00000140536Erbin; Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated ERBB2 'Tyr-1248' receptor, it may contribute to stabilize this unphosphorylated state (By similarit [...]
Gm20883 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140542Predicted gene, 20883.
Casp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140546Caspase-8 subunit p10; Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD [...]
Gm49416 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140564Predicted gene, 49416.
Gm20817 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140565Predicted gene, 20817.
Dnajb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140566DnaJ homolog subfamily B member 2; Functions as a co-chaperone, regulating the substrate binding and activating the ATPase activity of chaperones of the HSP70/heat shock protein 70 family. In par [...]
Gm10352 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140575Predicted gene 10256.
Prkn protein networkhttps://string-db.org/network/10090.ENSMUSP00000140587E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SY [...]
Fat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140596FAT atypical cadherin 1.
Kansl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140597KAT8 regulatory NSL complex subunit 3; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulatio [...]
Zfy1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140600Zinc finger Y-chromosomal protein 1; Probable transcriptional activator. Binds to the consensus sequence 5'-AGGCCY-3' (By similarity).
Dcdc2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000140603Doublecortin domain-containing protein 2C.
Gm21739 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140604Predicted gene, 21739.
Gm20916 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140607Predicted gene, 20916.
Mndal protein networkhttps://string-db.org/network/10090.ENSMUSP00000140610Myeloid cell nuclear differentiation antigen-like protein; Suppresses cell growth when expressed ectopically.
Slc35a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140615Probable UDP-sugar transporter protein SLC35A4.
Rgs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140624Regulator of G-protein signaling 1; Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene recept [...]
Zfp951 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140625Zinc finger protein 951.
Gm20838 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140626Predicted gene, 20838.
Gm28897 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140644Predicted gene 28897.
Gm28998 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140653Predicted gene 28576.
Tuba4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000140657Tubulin alpha-4A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha [...]
Gm20814 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140666Predicted gene, 20814.
Gm21497 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140668Predicted gene, 21497.
Usp37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140670Ubiquitin carboxyl-terminal hydrolase 37; Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2) [...]
Rbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140676Retinol-binding protein 2; Intracellular transport of retinol; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Gm20920 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140677Predicted gene, 20920.
Gm21865 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140679Predicted gene, 21865.
Gm20897 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140689Predicted gene, 20897.
Gm21704 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140704Predicted gene, 21704.
Gm21760 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140706Predicted gene, 21760.
Gm28576 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140720Predicted gene 28576.
Soat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140721Sterol O-acyltransferase 1; Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary choles [...]
Nipsnap3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000140727Nipsnap homolog 3A.
Gm20905 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140730Predicted gene, 20905.
Gm20908 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140733Predicted gene, 20908.
2610044O15Rik8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140736RIKEN cDNA 2610044O15 gene.
Dop1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000140740Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes.
Zfp383 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140742Zinc finger protein 383.
Terf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140744Telomeric repeat-binding factor 1; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component o [...]
Csta2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140745Cystatin A family member 2; Belongs to the cystatin family.
Thap4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140761THAP domain-containing protein 4.
Ms4a4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000140768Membrane-spanning 4-domains, subfamily A, member 4A.
Gm28490 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140770Predicted gene 28490.
CN725425 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140772cDNA sequence CN725425.
Gm28308 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140776Predicted gene 28308.
Lmbrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140783Probable lysosomal cobalamin transporter; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity); Belongs to th [...]
Krtap5-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140784Keratin-associated protein 5-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated protein (KRTAP), which a [...]
Gm21518 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140794Predicted gene, 21518.
Gm20809 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140802Predicted gene, 20809.
Gm5891 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140803Predicted gene 5891.
Ovol3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140811Putative transcription factor ovo-like protein 3; May act as a transcription regulator; Belongs to the krueppel C2H2-type zinc-finger protein family.
Gm20834 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140814Predicted gene, 20834.
Vgf protein networkhttps://string-db.org/network/10090.ENSMUSP00000140815Neuroendocrine regulatory peptide-1; [Neurosecretory protein VGF]: Secreted polyprotein that is packaged and proteolytically processed by prohormone convertases PCSK1 and PCSK2 in a cell-type-spe [...]
Scgb1b18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140824Secretoglobin, family 1B, member 18.
Ace3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140827Angiotensin-converting enzyme-like protein Ace3; Belongs to the peptidase M2 family.
Tbrg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140835FAST kinase domain-containing protein 4; Plays a role in processing of mitochondrial RNA precursors and in stabilization of a subset of mature mitochondrial RNA species, such as MT-CO1, MT-CO2, M [...]
Prmt6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140836Protein arginine N-methyltransferase 6; Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong [...]
Fam181a protein networkhttps://string-db.org/network/10090.ENSMUSP00000140842Family with sequence similarity 181, member A.
Gm21409 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140850Predicted gene, 21409.
Gm21627 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140851Predicted gene, 21627.
Cyp4a30b protein networkhttps://string-db.org/network/10090.ENSMUSP00000140857Cytochrome P450, family 4, subfamily a, polypeptide 30b; Belongs to the cytochrome P450 family.
Dnpep protein networkhttps://string-db.org/network/10090.ENSMUSP00000140864Aspartyl aminopeptidase; Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important role in intracellular protein and peptide metabolism (By simil [...]
Cabyr protein networkhttps://string-db.org/network/10090.ENSMUSP00000140870Calcium-binding tyrosine phosphorylation-regulated protein; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. May bind c [...]
Gm20777 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140872Predicted gene, 20777.
Krtap15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140888Keratin-associated protein 15-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which [...]
Rnf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140896E3 ubiquitin-protein ligase RING2; E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene re [...]
Nek7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140903Serine/threonine-protein kinase Nek7; Protein kinase which plays an important role in mitotic cell cycle progression. Required for microtubule nucleation activity of the centrosome, robust mitoti [...]
Gm7145 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140916Predicted gene 7145.
1700020D05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000140922RIKEN cDNA 1700020D05 gene.
H2al1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000140925H2A histone family member L1A.
Cd247 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140926T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cell [...]
Gm21294 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140933Predicted gene, 21294.
Gm10256 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140936Predicted gene 10256.
Cacna1e protein networkhttps://string-db.org/network/10090.ENSMUSP00000140937Voltage-dependent R-type calcium channel subunit alpha-1E; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of c [...]
Gm21256 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140938Predicted gene, 21256.
Tnnt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140941Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase [...]
Gm20835 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140944Predicted gene, 20835.
Gm20824 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140952Predicted gene, 20824.
Ms4a12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140981Membrane-spanning 4-domains, subfamily A, member 12.
Gm20792 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140983Predicted gene, 20792.
Larp4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000140993La-related protein 4B; Stimulates mRNA translation.
Ms4a14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140996Membrane-spanning 4-domains, subfamily A, member 14.
Gm4301 protein networkhttps://string-db.org/network/10090.ENSMUSP00000140999Predicted gene 4301.
Rbbp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141003Retinoblastoma-binding protein 5; As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for [...]
Gm20850 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141004Predicted gene, 20850.
Slurp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141013Secreted Ly-6/uPAR-related protein 1; Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity [...]
Smok3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000141020Sperm motility kinase 3C.
Glrx2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141022Glutaredoxin-2, mitochondrial; Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved i [...]
Gm20830 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141026Predicted gene, 20830.
Gm20894 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141039Predicted gene, 20894.
Gm21761 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141043Predicted gene, 21761.
Zfp287 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141046Zinc finger protein 287; May be involved in transcriptional regulation.
Gm20806 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141047Predicted gene, 20806.
Paqr8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141054Membrane progestin receptor beta; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(i) mediated pathway (By similarity). May be involved in oocyte maturat [...]
Zfp850 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141063Zinc finger protein 850.
Sh2d1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000141070SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In S [...]
Teddm3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141078Transmembrane epididymal family member 3.
Gm28778 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141087Predicted gene 28778.
Gm21394 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141090Predicted gene, 21394.
Gm21650 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141092Predicted gene, 21650.
Ppp1r18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141094Phostensin; May target protein phosphatase 1 to F-actin cytoskeleton.
Mybph protein networkhttps://string-db.org/network/10090.ENSMUSP00000141104Myosin-binding protein H; Binds to myosin; probably involved in interaction with thick myofilaments in the A-band; Belongs to the immunoglobulin superfamily. MyBP family.
Mtln protein networkhttps://string-db.org/network/10090.ENSMUSP00000141107Mitoregulin; Positively regulates mitochondrial complex assembly and/or stability. Increases mitochondrial membrane potential and mitochondrial respiration rate while decreasing mitochondrial rea [...]
Gm29049 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141109Predicted gene 29049.
Gm21094 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141113Predicted gene, 21094.
Krtap5-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141116Keratin-associated protein 5-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated protein (KRTAP), which a [...]
Shisal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141117Protein shisa-like-1.
Btbd35f16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141118BTB domain-containing 35, family member 16.
Gm20903 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141119Predicted gene, 20903.
Cys1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141121Cystin-1.
Muc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141128Mucin-2; Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents a [...]
Stat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141132Signal transducer and activator of transcription 1; Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines an [...]
Gm20911 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141161Predicted gene, 20911.
Gm28635 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141166Predicted gene 28635.
Carf protein networkhttps://string-db.org/network/10090.ENSMUSP00000141169Calcium-responsive transcription factor; Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calci [...]
Gm21996 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141173Predicted gene 21996.
Wdhd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141182WD repeat and HMG-box DNA-binding protein 1; Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA [...]
Gm3376 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141183RNA-binding motif protein, Y chromosome, family 1 member B; RNA-binding protein which may be involved in spermatogenesis. Required for sperm development, possibly by participating in pre-mRNA spl [...]
Elf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141197ETS-related transcription factor Elf-2; Probably transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter.
Kpna4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141227Importin subunit alpha-3; Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or biparti [...]
Slitrk3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141236SLIT and NTRK-like protein 3; Suppresses neurite outgrowth.
Gm35134 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141239Predicted gene, 35134.
Zc3h11a-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141255Zinc finger CCCH type containing 11A.
Mia3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141268Transport and Golgi organization protein 1 homolog; Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated [...]
Gm9774 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141274Predicted pseudogene 9774.
2210017I01Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000141278RIKEN cDNA 2210017I01 gene.
Hyal2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141280Hyaluronidase-2; Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displ [...]
2310046K23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000141296RIKEN cDNA 2310046K23 gene.
Tdpoz2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141299TD and POZ domain-containing protein 2.
Pabpc4l protein networkhttps://string-db.org/network/10090.ENSMUSP00000141300Poly(A)-binding protein, cytoplasmic 4-like.
Lin9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141331Protein lin-9 homolog; Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expres [...]
Zfp639 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141341Zinc finger protein 639; Binds DNA and may function as a transcriptional repressor.
Pcdhgb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141348Protocadherin gamma subfamily B, 1.
Gm30737 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141356Predicted gene, 30737.
Pcdhga10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141359Protocadherin gamma subfamily A, 10.
Gm6525 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141377Predicted pseudogene 6525.
Rgs7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141380Regulator of G-protein signaling 7; Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby dr [...]
Gm28870 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141382Predicted gene 28870.
Pcdh9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141396Protocadherin 9.
Gm5150 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141397SIRP beta 1 like 1 protein.
Map4k4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141400Mitogen-activated protein kinase kinase kinase kinase 4; Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstr [...]
Pcdha4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141408Protocadherin alpha-4; Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination (Probable). Thereby, it is involved in the establishment and maintena [...]
Gm21366 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141418Predicted gene, 21366.
Gm8797 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141419Predicted pseudogene 8797.
Dchs2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141425Dachsous cadherin-related 2.
Gm21440 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141432Predicted gene, 21440.
Tmem131l protein networkhttps://string-db.org/network/10090.ENSMUSP00000141438Transmembrane protein 131-like; In its membrane-associated form, antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte prolif [...]
Ddr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141443Discoidin domain-containing receptor 2; Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, [...]
Slamf6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141448SLAM family member 6; Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating t [...]
Pcdhgb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141449Protocadherin gamma subfamily B, 2.
Tigd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141473Tigger transposable element derived 5; Belongs to the tigger transposable element derived protein family.
Pcdhga2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141482Protocadherin gamma subfamily A, 2.
Olah protein networkhttps://string-db.org/network/10090.ENSMUSP00000141485S-acyl fatty acid synthase thioesterase, medium chain; Contributes to the release of free fatty acids from fatty acid synthase (FASN). Has broad substrate specificity, giving rise to a range of f [...]
Larp1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000141487La ribonucleoprotein domain family, member 1B.
Sirpb1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000141504Signal-regulatory protein beta 1A.
Pcdhb22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141521Protocadherin beta 22.
Snurf protein networkhttps://string-db.org/network/10090.ENSMUSP00000141531SNRPN upstream reading frame protein.
Gm21425 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141545Predicted gene, 21425.
Tnr protein networkhttps://string-db.org/network/10090.ENSMUSP00000141553Tenascin-R; Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. Theses interactions can influence cellular behavior by either evoking a [...]
Cox5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000141554Cytochrome c oxidase subunit 5B.
Dusp27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141564Inactive dual specificity phosphatase 27; May be required for myofiber maturation. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
Tdpoz8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141574TD and POZ domain-containing 8.
Fndc3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000141620Fibronectin type III domain-containing protein 3B; May be positive regulator of adipogenesis; Belongs to the FNDC3 family.
Gm33815 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141626Predicted gene, 33815.
Pigc protein networkhttps://string-db.org/network/10090.ENSMUSP00000141646Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N- acetylglucosami [...]
Fgg protein networkhttps://string-db.org/network/10090.ENSMUSP00000141648Fibrinogen gamma chain; Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix (By similarity). Fibrin has a major function in hemostasis a [...]
Syngap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141686Ras/Rap GTPase-activating protein SynGAP; Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in [...]
Pcdhga7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141704Protocadherin gamma subfamily A, 7.
Spata45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141721Spermatogenesis-associated protein 45; Belongs to the SPATA45 family.
Cep170 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141769Centrosomal protein of 170 kDa; Plays a role in microtubule organization. Required for centriole subdistal appendage assembly.
Gm29866 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141776Predicted gene, 29866.
Gm31571 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141784Predicted gene, 31571.
Gpatch4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141786G patch domain-containing protein 4.
Pcdh15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141792Protocadherin-15; Calcium-dependent cell-adhesion protein. Required for inner ear neuroepithelial cell elaboration and cochlear function. Probably involved in the maintenance of normal retinal fu [...]
Gm9117 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141802Predicted pseudogene 9117.
Gm21454 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141810Predicted gene, 21454.
Il7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141845Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation.
Gm37013 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141847Predicted gene, 37013.
Apeh protein networkhttps://string-db.org/network/10090.ENSMUSP00000141856Acylamino-acid-releasing enzyme; This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N- [...]
Sema3f protein networkhttps://string-db.org/network/10090.ENSMUSP00000141865Semaphorin-3F.
Slamf7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141871SLAM family member 7; Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating t [...]
Kcnk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141891Potassium channel subfamily K member 2; Ion channel that contributes to passive transmembrane potassium transport. Reversibly converts between a voltage-insensitive potassium leak channel and a v [...]
Pcdhga5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141893Protocadherin gamma subfamily A, 5.
Olfr220 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141919Olfactory receptor.
Nsun6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141924tRNA (cytosine(72)-C(5))-methyltransferase NSUN6; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in tRNA(Thr)(TGT) and tRNA(Cys)(G [...]
Mynn protein networkhttps://string-db.org/network/10090.ENSMUSP00000141951Myoneurin; Belongs to the krueppel C2H2-type zinc-finger protein family.
Nme7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141963Nucleoside diphosphate kinase 7; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism [...]
AF067063 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141964cDNA sequence AF067063.
Crnn protein networkhttps://string-db.org/network/10090.ENSMUSP00000141980Cornulin.
Osbpl9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141991Oxysterol-binding protein-related protein 9.
Pcdhgb7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000141997Protocadherin gamma subfamily B, 7.
Flg protein networkhttps://string-db.org/network/10090.ENSMUSP00000142003Filaggrin.
Pcdhgb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142010Protocadherin gamma subfamily B, 5.
Tdpoz6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142038TD and POZ domain-containing 6.
Tmco1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142042Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis. In response to endoplasmi [...]
Agrp protein networkhttps://string-db.org/network/10090.ENSMUSP00000142044Agouti-related protein; Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antag [...]
Olfr414 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142051Olfactory receptor.
Lamb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142053Laminin subunit beta-3; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development [...]
Rcor3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142054REST corepressor 3; May act as a component of a corepressor complex that represses transcription.
Pcdhga1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142062Protocadherin gamma subfamily A, 1.
Pfkfb3 protein networkhttps://string-db.org/network/10090.ENSMUSP000001420796-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 splice variant 2.
Gm20831 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142081Predicted gene, 20831.
D13Ertd608e protein networkhttps://string-db.org/network/10090.ENSMUSP00000142107DNA segment, Chr 13, ERATO Doi 608,-expressed.
Dag1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142109Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelinat [...]
Sprr2a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142110Small proline-rich protein 2A3.
Fer1l5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142130Fer-1-like protein 5; Plays a role in myoblast fusion; probable mediator of endocytic recycling for membrane trafficking events during myotube formation.
Gucy1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142138Guanylate cyclase soluble subunit alpha-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Pcdhga4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142140Protocadherin gamma-A4; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (By similarity).
Tgfb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142149Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) ch [...]
Pcdha7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142156Protocadherin alpha-7; Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination. Thereby, it is involved in the establishment and maintenance of spec [...]
Pcdha8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142159Protocadherin alpha 8.
Gm20773 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142165Predicted gene, 20773.
Cnga3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142175Cyclic nucleotide-gated cation channel alpha-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP w [...]
Tbl1xr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142184F-box-like/WD repeat-containing protein TBL1XR1; F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an [...]
Gm20807 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142185Predicted gene, 20807.
Pex5l protein networkhttps://string-db.org/network/10090.ENSMUSP00000142196PEX5-related protein; Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence. Belongs t [...]
Nlgn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142200Neuroligin-1; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and pro [...]
Gm42417 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142202Predicted gene, 42417.
Mme protein networkhttps://string-db.org/network/10090.ENSMUSP00000142205Neprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and L [...]
Fcrl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142210Fc receptor-like protein 5.
Pcdhgb4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142227Protocadherin gamma subfamily B, 4.
Btbd18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142247BTB/POZ domain-containing protein 18; Specifically required during spermatogenesis to promote expression of piRNA precursors. The piRNA metabolic process mediates the repression of transposable e [...]
Il1rl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142248Interleukin-1 receptor-like 2; Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor comp [...]
Gm28040 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142264Predicted gene, 28040.
Sema4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000142284Semaphorin-4C; Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-124 [...]
Camsap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142299Calmodulin-regulated spectrin-associated protein 2; Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organ [...]
Tmem131 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142307Transmembrane protein 131; May play a role in the immune response to viral infection; Belongs to the TMEM131 family.
Pcdh7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142319Protocadherin 7.
Astn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142322Astrotactin-1; Neuronal adhesion molecule that is required for normal migration of young postmitotic neuroblasts along glial fibers, especially in the cerebellum. Required for normal rate of migr [...]
Klhdc8b protein networkhttps://string-db.org/network/10090.ENSMUSP00000142325Kelch domain-containing protein 8B; Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis. Required for mitotic integrity and maintenance of chromosomal stabilit [...]
Zcchc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142363Zinc finger CCHC domain-containing protein 8; Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex. NEXT functions as an RNA exosome cofactor that directs a subset of non- [...]
Pfkfb4 protein networkhttps://string-db.org/network/10090.ENSMUSP000001423786-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4; Synthesis and degradation of fructose 2,6-bisphosphate. In the C-terminal section; belongs to the phosphoglycerate mutase family.
Rimbp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142455RIMS-binding protein 2; Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B.
Chil5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142477Chitinase-like 5; Belongs to the glycosyl hydrolase 18 family.
Sbno1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142481Protein strawberry notch homolog 1; Belongs to the SBNO family.
Lrrc7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142498Leucine-rich repeat-containing protein 7; Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N- [...]
Tlr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142500Toll-like receptor 1; Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate i [...]
Gatad2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000142514Transcriptional repressor p66-beta; Transcriptional repressor (By similarity). Enhances MBD2- mediated repression. Efficient repression requires the presence of GATAD2A (By similarity). Targets M [...]
Gbp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142518Guanylate-binding protein 6.
Hsd3b4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142522Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4.
Fam241a protein networkhttps://string-db.org/network/10090.ENSMUSP00000142535Uncharacterized protein FAM241A.
Spink8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142586Serine protease inhibitor Kazal-type 8; Probable serine protease inhibitor.
Stard3nl protein networkhttps://string-db.org/network/10090.ENSMUSP00000142680STARD3 N-terminal-like protein; Tethering protein that creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic [...]
Ccna1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142692Cyclin-A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additi [...]
Gm43738 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142694Predicted gene 43738.
Cfap47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142707Cilia and flagella-associated protein 47.
Usp33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142708Ubiquitin carboxyl-terminal hydrolase 33; Deubiquitinating enzyme involved in various processes such as centrosome duplication, cellular migration and beta-2 adrenergic receptor/ADRB2 recycling. [...]
Tfr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142720Transferrin receptor protein 2; Mediates cellular uptake of transferrin-bound iron in a non- iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differe [...]
Pitpnb protein networkhttps://string-db.org/network/10090.ENSMUSP00000142732Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.
Pdlim5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142737PDZ and LIM domain protein 5.
Amph protein networkhttps://string-db.org/network/10090.ENSMUSP00000142766Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity) [...]
Gm7879 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142767Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophi [...]
Fdps protein networkhttps://string-db.org/network/10090.ENSMUSP00000142770Farnesyl pyrophosphate synthase; Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites includ [...]
Elp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142823Elongator complex protein 6; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in trans [...]
Dnase2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000142872Deoxyribonuclease-2-beta; Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
Chd8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142890Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structu [...]
Gabra2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142892Gamma-aminobutyric acid receptor subunit alpha-2; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. [...]
Grin2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000142900Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sens [...]
Med12l protein networkhttps://string-db.org/network/10090.ENSMUSP00000142903Mediator of RNA polymerase II transcription subunit 12-like protein; May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase [...]
Bmp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142907Bone morphogenetic protein 3; Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.
Ccdc144b protein networkhttps://string-db.org/network/10090.ENSMUSP00000142910Coiled-coil domain-containing 144B.
P2ry14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000142934P2Y purinoceptor 14; Receptor for UDP-glucose coupled to G-proteins.
Ambn protein networkhttps://string-db.org/network/10090.ENSMUSP00000142944Ameloblastin; Involved in the mineralization and structural organization of enamel.
Fgfbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143011Fibroblast growth factor-binding protein 1; Acts as a carrier protein that releases fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhances the mitogenic ac [...]
Tet2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143029Methylcytosine dioxygenase TET2; Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active D [...]
P2ry12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143036P2Y purinoceptor 12; Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Required for normal platelet aggregation and blood coagulation.
Ankle2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143044Ankyrin repeat and LEM domain-containing protein 2; Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. Coordinates the control of BAF [...]
5730480H06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000143072PACRG-like protein.
Oaz3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143080Ornithine decarboxylase antizyme 3; Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increa [...]
Asic3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143083Acid-sensing ion channel 3; Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast [...]
Fgf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143094Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an impor [...]
Lgi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143128Leucine-rich glioma-inactivated protein 1; Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure medi [...]
Gm21083 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143130Predicted gene, 21083.
Olfr576 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143172Olfactory receptor.
Rbm8a protein networkhttps://string-db.org/network/10090.ENSMUSP00000143190RNA-binding protein 8A; Required for pre-mRNA splicing as component of the spliceosome (By similarity). Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited [...]
Fam220a-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143202Family with sequence similarity 220, member A.
Sass6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143233Spindle assembly abnormal protein 6 homolog; Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for [...]
Stap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143251Signal-transducing adaptor protein 1; May function as an adapter molecule downstream of KIT in the proliferation or differentiation of hematopoietic stem cells.
Frrs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143255Ferric-chelate reductase 1; Ferric-chelate reductases reduce Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm.
Atg4a-ps protein networkhttps://string-db.org/network/10090.ENSMUSP00000143291Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.
Rufy3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143302Protein RUFY3; Plays a role in the generation of neuronal polarity formation and axon growth. Implicated in the formation of a single axon by developing neurons. May inhibit the formation of addi [...]
Rtp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143305Receptor-transporting protein 3; Promotes functional cell surface expression of the bitter taste receptors TAS2R16 and TAS2R43; Belongs to the TMEM7 family.
Sh3glb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143312Endophilin-B1; May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with [...]
Csn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143341Beta-casein; Important role in determination of the surface properties of the casein micelles.
Celf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143344CUGBP Elav-like family member 3; RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre- mRNA that are subject to tissue- [...]
Gm21149 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143356Predicted gene, 21149.
Nhlh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143362Helix-loop-helix protein 2; May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.
Mef2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000143401Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphog [...]
Fbxw14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143404F-box and WD-40 domain protein 14.
Hgf protein networkhttps://string-db.org/network/10090.ENSMUSP00000143424Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and c [...]
Smr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143443Submaxillary gland androgen-regulated protein 2, isoform delta; May play a role in protection or detoxification.
Tex13c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143486TEX13 family member C2.
Ift22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143488Intraflagellar transport protein 22 homolog; Small GTPase-like component of the intraflagellar transport (IFT) complex B.
Gm5565 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143497Predicted gene 5565.
Mknk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143508MAP kinase-interacting serine/threonine-protein kinase 2; Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E. May play a role in the response to environmental stress [...]
Ulk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143536Serine/threonine-protein kinase ULK1; Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the format [...]
Zfp804b protein networkhttps://string-db.org/network/10090.ENSMUSP00000143568Zinc finger protein 804B.
Lhfpl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143576LHFPL tetraspan subfamily member 3 protein; Belongs to the LHFP family.
Gm21190 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143589Predicted gene, 21190.
Ugt8a protein networkhttps://string-db.org/network/10090.ENSMUSP000001436052-hydroxyacylsphingosine 1-beta-galactosyltransferase; Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingo [...]
Ube2d3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143608Ubiquitin-conjugating enzyme E2 D3; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'-linked polyubi [...]
Gm17660 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143623Secretory calcium-binding phosphoprotein proline-glutamine rich 1 variant 1.
Adgrl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143626Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exo [...]
Tm4sf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143652Transmembrane 4 L6 family member 1.
Rpe65 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143654Retinoid isomerohydrolase; Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins. Catalyzes the cleavage and isomeriza [...]
Nub1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143657NEDD8 ultimate buster 1; Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation (By similarity).
Gm21680 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143671Predicted gene, 21680.
Camk2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000143677Calcium/calmodulin-dependent protein kinase type II subunit delta; Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling [...]
Crip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143680Cysteine-rich protein 1; Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein.
Gpr87 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143683G-protein coupled receptor 87; Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage (By similarity).
Rnf216 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143705E3 ubiquitin-protein ligase RNF216; Acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their deg [...]
Slc7a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143743Y+L amino acid transporter 1; Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to [...]
St6galnac3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143747Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; Involved in the biosynthesis of ganglioside GD1A from GM1B. Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc residue on NeuAc-a [...]
Usp29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143769Ubiquitin carboxyl-terminal hydrolase 29; Belongs to the peptidase C19 family.
Ints1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143789Integrator complex subunit 1; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The [...]
Zfp936 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143800Zinc finger protein 936.
N4bp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143807NEDD4-binding protein 2.
0610012G03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000143811RIKEN cDNA 0610012G03 gene.
Gm42906 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143819Predicted gene 42906.
Sds protein networkhttps://string-db.org/network/10090.ENSMUSP00000143838L-serine dehydratase/L-threonine deaminase; Belongs to the serine/threonine dehydratase family.
Zfp958 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143842Zinc finger protein 958.
Tex26 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143851Testis-expressed protein 26.
Specc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143853Cytospin-B.
Gm5767 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143858Predicted gene 5767.
Ube3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000143859Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several su [...]
Olfr1408 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143864Olfactory receptor.
Nrbp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143872Nuclear receptor-binding protein; May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases.
Fbxo21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143873F-box only protein 21; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
AA792892 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143886Expressed sequence AA792892.
Gm38100 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143887Beclin-2; Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of [...]
Eif4h protein networkhttps://string-db.org/network/10090.ENSMUSP00000143910Eukaryotic translation initiation factor 4H; Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA (By similarity).
9130230L23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000143918RIKEN cDNA 9130230L23 gene.
D5Ertd577e protein networkhttps://string-db.org/network/10090.ENSMUSP00000143927DNA segment, Chr 5, ERATO Doi 577,-expressed.
Gm7792 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143931Predicted gene 7792.
Clock protein networkhttps://string-db.org/network/10090.ENSMUSP00000143939Circadian locomoter output cycles protein kaput; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates var [...]
Spam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143970Hyaluronidase PH-20; Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus [...]
Gm16429 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143980Predicted gene 16429.
Gm43638 protein networkhttps://string-db.org/network/10090.ENSMUSP00000143986Predicted gene 43638; Belongs to the UDP-glycosyltransferase family.
Gm3139 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144005Predicted gene 3139.
Hyal5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144011Hyaluronidase-5; Catalyzes the hydrolysis of hyaluronan into smaller oligosaccharide fragments. Does not appear to be essential for fertilization.
Zfp811 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144038Zinc finger protein 811.
Plb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144040Phospholipase B1, membrane-associated; Membrane-associated phospholipase. Exhibits a calcium- independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Prefer [...]
Med13l protein networkhttps://string-db.org/network/10090.ENSMUSP00000144092Mediator of RNA polymerase II transcription subunit 13-like; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent gen [...]
Gm7978 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144093Predicted gene 7978.
Cxcl17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144096C-X-C motif chemokine 17; Chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an [...]
Myo1h protein networkhttps://string-db.org/network/10090.ENSMUSP00000144110Unconventional myosin-Ih; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind [...]
Mpv17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144119Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis (By similarity). Involved in [...]
Rbm47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144122RNA-binding protein 47; Belongs to the RRM RBM47 family.
Zfp433 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144123Zinc finger protein 433.
Zfp825 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144128Zinc finger protein 825.
Olfr1118 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144143Olfactory receptor.
Ppef2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144157Serine/threonine-protein phosphatase with EF-hands 2; May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic curr [...]
Pds5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000144171Sister chromatid cohesion protein PDS5 homolog A; Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chro [...]
Gm7697 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144181Predicted gene 7697.
6720489N17Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000144207RIKEN cDNA 6720489N17 gene.
Sept11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144235Septin-11; Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spi [...]
Gm42742 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144243PAXIP1-associated glutamate-rich protein 1A; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in associ [...]
Slc4a1ap protein networkhttps://string-db.org/network/10090.ENSMUSP00000144257Solute carrier family 4 (anion exchanger), member 1, adaptor protein.
Olfr519 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144271Olfactory receptor.
Eno4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144272Enolase 4; Required for sperm motility, function and male fertility. May be involved in the normal assembly of the sperm fibrous sheath and provides most of the enolase activity in sperm.
Gm5141 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144368Zinc finger protein.
Morc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144369MORC family CW-type zinc finger protein 3; Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (By similarity). Sumoylated MORC3-NBs can also associate with PML-N [...]
Gm9495 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144411Predicted gene 9495.
Hsph1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144413Heat shock protein 105 kDa; Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate pro [...]
Pagr1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000144469PAXIP1 associated glutamate rich protein 1A.
Zfp799 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144480Zinc finger protein 799.
Rogdi protein networkhttps://string-db.org/network/10090.ENSMUSP00000144481Protein rogdi homolog; Belongs to the rogdi family.
Tmem270 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144496Transmembrane protein 270.
Oas1e protein networkhttps://string-db.org/network/10090.ENSMUSP000001445292'-5' oligoadenylate synthetase 1E.
Pds5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000144572Sister chromatid cohesion protein PDS5 homolog B; Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid coh [...]
Gm10424 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144603Predicted gene 10424.
Tmem214 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144615Transmembrane protein 214; Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum str [...]
Mageb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144620Melanoma antigen, family B, 2.
Bend4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144639BEN domain-containing protein 4.
AU041133 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144661Expressed sequence AU041133.
Olfr444 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144691Olfactory receptor.
Vsig10l protein networkhttps://string-db.org/network/10090.ENSMUSP00000144692V-set and immunoglobulin domain-containing protein 10-like.
Naaladl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144706N-acetylated alpha-linked acidic dipeptidase-like 2.
AW822073 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144714Expressed sequence AW822073.
Olfr798 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144716Olfactory receptor.
Il5ra protein networkhttps://string-db.org/network/10090.ENSMUSP00000144718Interleukin-5 receptor subunit alpha; This is the receptor for interleukin-5. The alpha chain binds to IL5.
Wdr49 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144721WD repeat domain 49.
Gm12845 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144740Predicted gene 12845.
Olfr802 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144741Olfactory receptor.
Olfr1375 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144756Olfactory receptor.
Eif4a3l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144809Eukaryotic translation initiation factor 4A3-like 1; Belongs to the DEAD box helicase family.
Olfr57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144814Olfactory receptor.
Olfr1356 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144815Olfactory receptor.
Suclg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144827Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synt [...]
Wdr19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144866WD repeat-containing protein 19; As component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPCRs), it is [...]
Ndufa9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144904NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not [...]
Ndufa4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144932Cytochrome c oxidase subunit NDUFA4; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory c [...]
Olfr821 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144938Olfactory receptor.
Olfr315 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144944Olfactory receptor.
Olfr770 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144950Olfactory receptor.
Rfc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144954Replication factor C subunit 1; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds t [...]
Klf15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144962Krueppel-like factor 15; Transcriptional regulator that binds to the GA element of the CLCNKA promoter (By similarity). Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in t [...]
Creb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144979Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription; Belongs to the bZIP family.
Zfp638 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144989Zinc finger protein 638; Transcription factor that binds to cytidine clusters in double-stranded DNA (By similarity). Plays a key role in the silencing of unintegrated retroviral DNA: some part o [...]
Prokr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000144999Prokineticin receptor 1; Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinosit [...]
Duxf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145004Double homeobox family member 3.
Gm44596 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145012Predicted gene 44596.
BC049715 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145015Uncharacterized protein C12orf60 homolog.
Smim4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145018Small integral membrane protein 4; Belongs to the SMIM4 family.
Olfr1357 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145032Olfactory receptor Olfr1357.
Olfr785 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145040Olfactory receptor.
Olfr774 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145042Olfactory receptor.
Emp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145069Epithelial membrane protein 1.
Rasgef1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000145077RasGEF domain family, member 1A.
Cyp26b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145092Cytochrome P450 26B1; Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Involved in the specific inactivation of all-trans-retinoic [...]
Olfr786 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145099Olfactory receptor.
Myadm protein networkhttps://string-db.org/network/10090.ENSMUSP00000145120Myeloid-associated differentiation marker.
Add2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145160Beta-adducin; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide [...]
Reg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145161Lithostathine-1; Might act as an inhibitor of spontaneous calcium carbonate precipitation.
Olfr457 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145162Olfactory receptor.
Cntn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145176Contactin-3; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity (By similarity); Belongs to the immunoglobulin superfami [...]
Zfp775 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145192Zinc finger protein 775; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Eif4a3l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145194Eukaryotic translation initiation factor 4A3-like 2; Belongs to the DEAD box helicase family.
Atp6v0e2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145198V-type proton ATPase subunit e 2; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Gimap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145211GTPase IMAP family member 3; During thymocyte development, may support the positive selection of CD4 and CD8 T cells. May play a role in mitochondrial DNA segregation in hematopoietic tissues. Bi [...]
Gimap8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145255GTPase IMAP family member 8; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections.
Olfr1383 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145258Olfactory receptor.
Olfr813 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145260Olfactory receptor.
Gpr162 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145267Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
Ghrl protein networkhttps://string-db.org/network/10090.ENSMUSP00000145281Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating ef [...]
Olfr794 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145301Olfactory receptor.
Tatdn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145308TatD DNase domain-containing 2.
Olfr808 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145315Olfactory receptor.
Olfr1386 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145320Olfactory receptor.
Galntl6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145321Polypeptide N-acetylgalactosaminyltransferase.
Olfr449 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145322Olfactory receptor.
Olfr211 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145330Olfactory receptor.
Spin2g protein networkhttps://string-db.org/network/10090.ENSMUSP00000145332Spindlin family, member 2G.
Gm45140 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145334Predicted gene 45140.
E330021D16Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000145343RIKEN cDNA E330021D16 gene.
BC029722 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145349cDNA sequence BC029722.
Rpl32 protein networkhttps://string-db.org/network/10090.ENSMUSP0000014535060S ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family.
Zfp964 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145354Zinc finger protein 964.
Olfr781 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145356Olfactory receptor.
C2cd5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145373C2 domain-containing protein 5; Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma [...]
Olfr325 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145386Olfactory receptor.
Olfr314 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145387Olfactory receptor.
Vmn1r21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145398Vomeronasal type-1 receptor.
Olfr803 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145400Olfactory receptor.
Rab11fip5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145402Rab11 family-interacting protein 5; Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulat [...]
Gm9780 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145436Predicted gene 9780.
Kcnj8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145440ATP-sensitive inward rectifier potassium channel 8; This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potass [...]
Prrt3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145443Proline-rich transmembrane protein 3.
Olfr1415 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145446Olfactory receptor.
Skap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145462Src kinase-associated phosphoprotein 2; May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a r [...]
Hspa4l protein networkhttps://string-db.org/network/10090.ENSMUSP00000145468Heat shock 70 kDa protein 4L; Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase.
Olfr777 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145475Olfactory receptor.
Gm44511 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145481Killer cell lectin-like receptor subfamily B member 1B allele A; Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I [...]
Olfr812 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145482Olfactory receptor.
Sinhcaf protein networkhttps://string-db.org/network/10090.ENSMUSP00000145487SIN3-HDAC complex-associated factor; Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathw [...]
Olfr437 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145490Olfactory receptor.
Tarm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145491T-cell-interacting, activating receptor on myeloid cells protein 1; May act as receptor. Negatively regulates TCR-mediated CD4(+) T cell proliferation and activation, possibly by binding an unkno [...]
D6Ertd527e protein networkhttps://string-db.org/network/10090.ENSMUSP00000145529DNA segment, Chr 6, ERATO Doi 527,-expressed.
Kctd14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145558Potassium channel tetramerisation domain-containing 14.
Olfr1508 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145649Olfactory receptor.
Olfr19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145655Olfactory receptor 19; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Zfp59 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145671Zinc finger protein 59; May have a role during differentiation processes. Belongs to the krueppel C2H2-type zinc-finger protein family.
Olfr196 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145684Olfactory receptor.
Gm30191 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145697Predicted gene, 30191.
Gp6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145740Platelet glycoprotein VI; Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin fo [...]
Olfr403 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145741Olfactory receptor Olfr403.
Bcl7c protein networkhttps://string-db.org/network/10090.ENSMUSP00000145743B-cell CLL/lymphoma 7 protein family member C; May play an anti-apoptotic role. Belongs to the BCL7 family.
Sh2b1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145754SH2B adapter protein 1; Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways mediated by Janus kinase (JAK) and receptor tyrosine ki [...]
Cd19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145803B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for [...]
Olfr43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145822Olfactory receptor Olfr43.
Olfr725 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145828Olfactory receptor.
Olfr741 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145848Olfactory receptor.
Emsy protein networkhttps://string-db.org/network/10090.ENSMUSP00000145858BRCA2-interacting transcriptional repressor EMSY; Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the [...]
Lrrc32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145859Transforming growth factor beta activator LRRC32; Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state d [...]
Olfr723 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145863Olfactory receptor.
Zg16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145876Zymogen granule membrane protein 16; May play a role in protein trafficking. May act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) an [...]
Olfr181 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145877Olfactory receptor 181; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr173 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145946Olfactory receptor.
Exosc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000145948Exosome complex component RRP46; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrad [...]
Plin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146028Perilipin-1; Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness (By similar [...]
Txnrd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146030Thioredoxin reductase 2, mitochondrial; Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling.
Gm36028 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146040Predicted gene, 36028.
Zfp109 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146043Zinc finger protein ZFP109.
Dedd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146052DNA-binding death effector domain-containing protein 2; May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of in [...]
Hapln3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146090Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding. Belongs to the HAPLN family.
Olfr11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146091Olfactory receptor 11; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Gucy2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000146093Guanylate cyclase D; Functions as an olfactory receptor activated by urine odorants, uroguanylin and guanylin and as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide [...]
Olfr165 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146100Olfactory receptor.
4930590J08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000146101Uncharacterized protein C3orf20 homolog.
Xrcc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146105DNA repair protein XRCC1; Involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes (By similarity). Probably during DNA repair, negatively regula [...]
Olfr1507 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146152Olfactory receptor.
Olfr465-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146183Olfactory receptor.
Phldb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146187Pleckstrin homology-like domain, family B, member 3.
Aqp11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146215Aquaporin-11; Channel protein that facilitates the transport of water, glycerol and hydrogen peroxide across membrane of cell or organelles guaranteeing intracellular homeostasis in several organ [...]
Zfp780b protein networkhttps://string-db.org/network/10090.ENSMUSP00000146224Zinc finger protein 780B.
Zfp114 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146241Zinc finger protein 114.
Zfp950 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146243Zinc finger protein 950.
Cbl protein networkhttps://string-db.org/network/10090.ENSMUSP00000146244E3 ubiquitin-protein ligase CBL; Adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. Acts as an E3 ubiqui [...]
Ppp4c protein networkhttps://string-db.org/network/10090.ENSMUSP00000146245Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs [...]
Hnrnpul1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146263Heterogeneous nuclear ribonucleoprotein U-like protein 1; Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated [...]
Zfp626 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146286Zinc finger protein 626.
Rnf40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146310E3 ubiquitin-protein ligase BRE1B; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a spec [...]
Olfr1437 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146333Olfactory receptor.
Olfr1298 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146343Olfactory receptor.
Olfr1461 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146358Olfactory receptor.
Sesn3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146362Sestrin-3; May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TO [...]
Fcor protein networkhttps://string-db.org/network/10090.ENSMUSP00000146366Foxo1-corepressor; Regulator of adipocytes that acts by repressing FOXO1 transcriptional activity. Acts by promoting acetylation of FOXO1, both by preventing the interaction between FOXO1 and SIR [...]
A26c2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146381ANKRD26-like family C, member 2.
Olfr193 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146393Olfactory receptor.
Olfr492 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146417Olfactory receptor 492; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1314 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146418Olfactory receptor.
Gm35339 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146420Predicted gene, 35339.
Olfr1309 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146426Olfactory receptor.
Olfr1294 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146438Olfactory receptor.
Fam181b protein networkhttps://string-db.org/network/10090.ENSMUSP00000146473Protein FAM181B.
Nap1l4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146474Nucleosome assembly protein 1-like 4; Acts as histone chaperone in nucleosome assembly. In condensing spermatids, mediates the loading of the heterodimer composed of histones H2AB1 and H2BC1/TH2B [...]
Picalm protein networkhttps://string-db.org/network/10090.ENSMUSP00000146501Phosphatidylinositol-binding clathrin assembly protein; Cytoplasmic adapter protein that plays a critical role in clathrin-mediated endocytosis which is important in processes such as internaliza [...]
Zfand6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146518AN1-type zinc finger protein 6; Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and d [...]
Olfr1432 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146529Olfactory receptor.
Olfr1301 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146530Olfactory receptor.
Gm9195 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146536Predicted gene 9195.
Mical3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146544[F-actin]-monooxygenase MICAL3; Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in [...]
Adam9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146545Disintegrin and metalloproteinase domain-containing protein 9; Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VC [...]
Olfr1493-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146547Olfactory receptor.
Olfr1424 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146552Olfactory receptor.
Olfr1494 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146563Olfactory receptor.
Olfr1463 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146566Olfactory receptor.
Smim27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146567Small integral membrane protein 27.
Rinl protein networkhttps://string-db.org/network/10090.ENSMUSP00000146576Ras and Rab interactor-like protein; Guanine nucleotide exchange factor (GEF) for RAB5A and RAB22A that activates RAB5A and RAB22A by exchanging bound GDP for free GTP. Plays a role in endocytosi [...]
Iqank1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146582Putative IQ motif and ankyrin repeat domain-containing protein LOC642574 homolog.
Map6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146585Microtubule-associated protein 6; Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity. Involved in dendrite [...]
Arhgap33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146602Rho GTPase-activating protein 33; May be involved in several stages of intracellular trafficking (By similarity). Could play an important role in the regulation of glucose transport by insulin. M [...]
Olfr1504 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146610Olfactory receptor.
Gm5737 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146629Predicted gene 5737.
Olfr1465 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146645Olfactory receptor.
Lyrm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146648LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes.
Fam81b protein networkhttps://string-db.org/network/10090.ENSMUSP00000146649Family with sequence similarity 81, member B.
Zfp654 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146656Zinc finger protein 654; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Trappc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146674Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily.
Myo16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146677Unconventional myosin-XVI; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind [...]
Pnpla6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146680Neuropathy target esterase; Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 [...]
Dmbt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146685Deleted in malignant brain tumors 1 protein; May play roles in mucosal defense system and cellular immune defense. May play a role in liver regeneration. May be an important factor in fate decisi [...]
Olfr1308 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146688Olfactory receptor.
Frmpd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146693FERM and PDZ domain-containing 2.
Tnfsf13b protein networkhttps://string-db.org/network/10090.ENSMUSP00000146694Tumor necrosis factor ligand superfamily member 13b, membrane form; Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 l [...]
Fam169b protein networkhttps://string-db.org/network/10090.ENSMUSP00000146700Protein FAM169B; Belongs to the FAM169 family.
Gm9999 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146705Predicted gene 9999.
Rnf227 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146712RING finger protein 227.
Ankrd31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146720Ankyrin repeat domain-containing protein 31; Required for DNA double-strand breaks (DSBs) formation during meiotic recombination. Regulates the spatial and temporal patterns of pre-DSB recombinos [...]
Gdf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146749Growth differentiation factor 1.
Gprc5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000146777G-protein coupled receptor family C group 5 member B; Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein s [...]
Olfr1480 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146782Olfactory receptor.
Homer2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146787Homer protein homolog 2; Postsynaptic density scaffolding protein. Binds and cross- links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 [...]
Psg22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146795Pregnancy-specific glycoprotein 22; May have an angiogenic function during early placental development. Binds to cell-surface heparan sulfate proteoglycans (HSPGs), and stimulates secretion of th [...]
Olfr1442 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146803Olfactory receptor 1442.
Olfr198 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146813Olfactory receptor.
Zfp14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146824Zinc finger protein 14; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Gm45015 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146837Predicted gene 45015.
Dcst2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146838DC-STAMP domain-containing 2.
Htatip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146858Oxidoreductase HTATIP2; Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear tran [...]
Olfr1451 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146874Olfactory receptor.
Zfp317 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146876Zinc finger protein 317.
Camsap3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146896Calmodulin-regulated spectrin-associated protein 3; Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organ [...]
Olfr206 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146906Olfactory receptor.
Gm15262 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146912Predicted gene 15262.
Zfp524 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146921Zinc finger protein 524; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Olfr1434 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146925Olfactory receptor.
Fam24a protein networkhttps://string-db.org/network/10090.ENSMUSP00000146929Protein FAM24A.
Gm4881 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146932ETS repressor factor-like.
Gm4756 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146943Predicted gene 4756; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Zfp358 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146953Zinc finger protein 358.
Gm18336 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146964Predicted gene, 18336.
Ckm protein networkhttps://string-db.org/network/10090.ENSMUSP00000146972Creatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy tran [...]
Gm35060 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146976Predicted gene, 35060.
Frmpd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146983FERM and PDZ domain-containing 3.
Cfap99 protein networkhttps://string-db.org/network/10090.ENSMUSP00000146999Cilia and flagella-associated protein 99.
U2af2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147013Splicing factor U2AF 65 kDa subunit; Plays a role in pre-mRNA splicing and 3'-end processing. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-ter [...]
Dnajb13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147019DnaJ homolog subfamily B member 13; Plays a role in the formation of the central complex of ciliary and flagellar axonemes.
Olfr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147026Olfactory receptor.
Gm6176 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147031Predicted gene 6176; Belongs to the protein kinase superfamily.
Olfr187 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147035Olfactory receptor 187; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Samd4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000147037Protein Smaug homolog 2; Has transcriptional repressor activity. Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A (By similarity); Belongs to the SMAUG family.
Aldoa-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147053Fructose-bisphosphate aldolase A.
Gm45208 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147061PRA1 family protein.
Olfr209 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147068Olfactory receptor.
Nkpd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147092NTPase KAP family P-loop domain-containing protein 1.
Kcnb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147093Potassium voltage-gated channel subfamily B member 1; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in t [...]
Muc16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147104Mucin 16.
Olfr1289 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147119Olfactory receptor.
Rapgef6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147135Rap guanine nucleotide exchange factor (GEF) 6.
Zfp78 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147154Zinc finger protein 78.
Gm19410 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147162Predicted gene, 19410.
Supt5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147164Transcription elongation factor SPT5; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. D [...]
Olfr136 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147166Olfactory receptor.
Olfr1462 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147174Olfactory receptor MOR202-13.
Olfr1466 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147188Olfactory receptor.
Olfr485 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147194Olfactory receptor.
Gm7271 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147216Exocyst complex component 1-like.
Nbdy protein networkhttps://string-db.org/network/10090.ENSMUSP00000147221Negative regulator of P-body association.
Gm44973 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147233Predicted gene 44973.
Gm13420 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147234Predicted gene 13420.
Ryr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147250Ryanodine receptor 3; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. M [...]
Eid3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147261EP300-interacting inhibitor of differentiation 3; Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The com [...]
Chmp1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000147285Charged multivesicular body protein 1b-1; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bo [...]
4930558C23Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000147291Cortexin domain containing 2.
Zbtb45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147298Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation.
Olfr538 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147315Olfactory receptor.
Gm40460 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147331Predicted gene, 39115.
Zfp791 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147335Zinc finger protein 791.
Gm28710 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147354Predicted gene 28710.
Zscan4e protein networkhttps://string-db.org/network/10090.ENSMUSP00000147356Zinc finger and SCAN domain-containing 4E.
Ifitm6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147357Interferon-induced transmembrane protein 6.
Tunar protein networkhttps://string-db.org/network/10090.ENSMUSP00000147361Tcl1 upstream neural differentiation-associated RNA.
Strit1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147363Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF; Enhances the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by displacing ATP2A1/SERCA1 inhibitors, thereby acting a [...]
Nucb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147383Nucleobindin-1; Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis (By similarity). Acts as a non-receptor guanine nucleotide exchange factor which binds to a [...]
Igip protein networkhttps://string-db.org/network/10090.ENSMUSP00000147405IgA-inducing protein.
Gm10131 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147411Predicted pseudogene 10131.
Rnf223 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147415RING finger protein 223.
Ins2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147425Insulin-2 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate [...]
Kcnj11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147439ATP-sensitive inward rectifier potassium channel 11; This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to f [...]
Olfr707 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147446Olfactory receptor.
Pkhd1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147447Fibrocystin-L.
Sorcs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147463VPS10 domain-containing receptor SorCS1.
Fbxo25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147467F-box only protein 25; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) pro [...]
Zfp541 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147475Zinc finger protein 541; Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis.
Slc8a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147497Sodium/calcium exchanger 2; Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca [...]
Ruvbl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147502RuvB-like 2; Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA helicase (5' to 3') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits [...]
Cfl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147514Cofilin-1; Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. [...]
Smim31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147515Small integral membrane protein 31.
Gm5678 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147517Predicted gene 5678; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Rtp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147521Receptor-transporting protein 4; Probable chaperone protein which facilitates trafficking and functional cell surface expression of some G-protein coupled receptors (GPCRs). Promotes functional e [...]
Zscan4-ps3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147528Zinc finger and SCAN domain containing 4, pseudogene 3.
Gm35315 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147534Zinc finger protein.
Lrrc3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000147537Leucine-rich repeat-containing 3C.
Gm7579 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147547Predicted gene 7579.
Pde2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000147553cGMP-dependent 3',5'-cyclic phosphodiesterase; Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important phys [...]
St6galnac2-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147566Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2.
Gm10153 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147568Predicted gene 10153.
Olfr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147586Olfactory receptor 5; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr601 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147592Olfactory receptor 601.
Olfr374 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147605Olfactory receptor.
Zfp42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147606Zinc finger protein 42; Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to [...]
Gm45716 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147615Small integral membrane protein 36.
Usp47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147619Ubiquitin carboxyl-terminal hydrolase 47; Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in ba [...]
Olfr506 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147623Olfactory receptor.
Ppp1r3b protein networkhttps://string-db.org/network/10090.ENSMUSP00000147633Protein phosphatase 1 regulatory subunit 3B; Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its [...]
Olfr488 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147652Olfactory receptor 488; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Cyld protein networkhttps://string-db.org/network/10090.ENSMUSP00000147654Ubiquitin carboxyl-terminal hydrolase CYLD; Deubiquitinase that specifically cleaves 'Lys-63'- and linear 'Met-1'-linked polyubiquitin chains and is involved in NF-kappa-B activation and TNF-alph [...]
Ptpre protein networkhttps://string-db.org/network/10090.ENSMUSP00000147656Receptor-type tyrosine-protein phosphatase epsilon; Isoform 1 acts as a negative regulator of insulin receptor (IR) signaling and is involved in insulin-induced glucose metabolism mainly through [...]
Olfr573-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147664Olfactory receptor 573, pseudogene 1.
Zfp143 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147673Zinc finger protein 143; Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in effic [...]
Bpnt1 protein networkhttps://string-db.org/network/10090.ENSMUSP000001476743'(2'),5'-bisphosphate nucleotidase 1; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Has 10 [...]
Gm17949 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147681Predicted gene, 17949; Belongs to the adenylate kinase family.
Cks1brt protein networkhttps://string-db.org/network/10090.ENSMUSP00000147685Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
Tmem241 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147687Transmembrane protein 241; Belongs to the TMEM241 family.
Exosc6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147696Exosome complex component MTR3; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degrada [...]
Olfr478 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147713Olfactory receptor 478; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Gm45861 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147714Predicted gene 45861.
Frat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147726Proto-oncogene FRAT1; Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 [...]
Gm36210 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147734Predicted gene, 36210.
Pvrig protein networkhttps://string-db.org/network/10090.ENSMUSP00000147735Poliovirus receptor-related immunoglobulin domain-containing.
Srek1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147737Splicing regulatory glutamine/lysine-rich protein 1; Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SF [...]
Saa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147751Serum amyloid A-2 protein; Major acute phase reactant. Apolipoprotein of the HDL complex.
Casp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147767Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) [...]
Usp17le protein networkhttps://string-db.org/network/10090.ENSMUSP00000147776Ubiquitin carboxyl-terminal hydrolase 17-like protein E; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include [...]
Gab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147784GRB2-associated-binding protein 1; Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably in [...]
Ccdc201 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147806Coiled coil domain 201.
Nek1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147809Serine/threonine-protein kinase Nek1; Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Involved in DNA damage checkpoint control and for proper DNA dam [...]
Gm45713 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147813Predicted gene 45713; Belongs to the universal ribosomal protein uL13 family.
Rpl18 protein networkhttps://string-db.org/network/10090.ENSMUSP0000014781660S ribosomal protein L18; Component of the large ribosomal subunit.
Gm45337 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147817Predicted gene 45337.
Olfr61 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147819Olfactory receptor.
Tmem238l protein networkhttps://string-db.org/network/10090.ENSMUSP00000147820Transmembrane protein 238-like.
Gm8773 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147824Predicted gene 8773.
Ebf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147829Transcription factor COE3; Transcriptional activator. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity); Belongs to the COE family.
Olfr370 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147834Olfactory receptor 370.
Best2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147837Bestrophin-2; Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
Gm45618 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147854Predicted gene 45618.
Gm4553 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147863Predicted gene 4553.
Zfp474 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147873Zinc finger protein 474.
Tfdp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147881Transcription factor Dp-1; Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter reg [...]
Olfr65 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147914Olfactory receptor.
Gm45623 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147916Predicted gene 45623.
Folr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147920Folate receptor beta; Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for fol [...]
Olfr490 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147922Olfactory receptor 490; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr548-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147923Olfactory receptor.
Rnh1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147928Ribonuclease inhibitor; Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis (By similarity).
Gm4869 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147930Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Olfr17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147931Olfactory receptor.
Gm45808 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147942Predicted gene 45808.
Tti2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147956TELO2-interacting protein 2; Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein [...]
Pom121l12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147960POM121 membrane glycoprotein-like 12.
Slc16a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147968Monocarboxylate transporter 2; Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-ch [...]
Lnp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147973Leukemia NUP98 fusion partner 1.
Glb1l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000147979Beta-galactosidase-1-like protein 3.
Arntl protein networkhttps://string-db.org/network/10090.ENSMUSP00000147989Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, [...]
A730046J19Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000148011Serine-rich and transmembrane domain-containing 2.
Bicra protein networkhttps://string-db.org/network/10090.ENSMUSP00000148012BRD4-interacting chromatin-remodeling complex-associated protein; Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure [...]
Prrg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148014Transmembrane gamma-carboxyglutamic acid protein 2.
Grtp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148042Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s).
Gm3854 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148053Predicted gene 3854.
Olfr494 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148063Olfactory receptor 494; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Gm2115 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148068Cortexin domain-containing 1.
Aldh16a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148069Aldehyde dehydrogenase family 16 member A1.
Isyna1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148077Inositol-3-phosphate synthase 1; Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1- phosphate in a NAD-dependent manner. Rat [...]
Il18bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000148080Interleukin-18-binding protein; Binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response (By similarity).
Vmn1r72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148081Vomeronasal type-1 receptor.
Gm28729 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148097Predicted gene 28729.
Ldha protein networkhttps://string-db.org/network/10090.ENSMUSP00000148107L-lactate dehydrogenase A chain; Belongs to the LDH/MDH superfamily. LDH family.
Nup98 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148115Nuclear pore complex protein Nup98-Nup96; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. NUP98 and NUP96 are involved in the bidirectional transport across the NPC. M [...]
Spaar protein networkhttps://string-db.org/network/10090.ENSMUSP00000148128Small regulatory polypeptide of amino acid response; Negative regulator of amino acid sensing and mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels an [...]
1810010H24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000148142UPF0450 protein C17orf58 homolog; Belongs to the UPF0450 family.
Cebpd protein networkhttps://string-db.org/network/10090.ENSMUSP00000148145CCAAT/enhancer-binding protein delta; Transcription activator that recognizes two different DNA motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many e [...]
Gm45785 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148146Predicted gene 45785.
Gm29735 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148147Predicted gene, 29735.
Zscan4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000148157Zinc finger and SCAN domain-containing 4B.
Olfr638 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148160Olfactory receptor.
Pfn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148168Profilin; Belongs to the profilin family.
Gm42372 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148171Predicted gene, 42372.
Gm45799 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148176Predicted gene 45799.
Olfr570 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148181Olfactory receptor.
Trpc5os protein networkhttps://string-db.org/network/10090.ENSMUSP00000148184Putative uncharacterized protein TRPC5OS homolog.
Gm32742 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148191Predicted gene, 32742.
Triml2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148196Tripartite motif family-like 2.
Nek5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148211Serine/threonine-protein kinase Nek5; Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Zfp873 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148219Zinc finger protein 873.
Anapc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148220Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the [...]
Gm45717 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148225Predicted gene 45717.
Olfr541 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148238Olfactory receptor.
Zscan18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148239Zinc finger and SCAN domain-containing 18.
Olfr291 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148266Olfactory receptor.
Cherp protein networkhttps://string-db.org/network/10090.ENSMUSP00000148273Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation.
Tmem269 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148286Transmembrane protein 269.
Olfr868 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148302Olfactory receptor.
Gm10358 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148326Glyceraldehyde-3-phosphate dehydrogenase.
Large1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148336LARGE xylosyl- and glucuronyltransferase 1; Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phospho [...]
Olfr887 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148361Olfactory receptor MOR162-5.
Fbxw27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148376F-box and WD-40 domain protein 27.
Zdhhc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148381Probable palmitoyltransferase ZDHHC1; Belongs to the DHHC palmitoyltransferase family.
Csnk2a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148404Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C- [...]
Crhr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148408Corticotropin-releasing factor receptor 2; G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a [...]
Gm45826 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148411Sperm-associated antigen 11; May have antimicrobial activity. May also play a role sperm maturation, storage, and protection.
Olfr835 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148416Olfactory receptor.
Axdnd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148420Axonemal dynein light chain domain-containing protein 1.
Carmil2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148422Capping protein, Arp2/3 and myosin-I linker protein 2; Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filamen [...]
Gm11639 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148433Predicted gene 11639.
Cdkn2aip protein networkhttps://string-db.org/network/10090.ENSMUSP00000148441CDKN2A-interacting protein; Regulates DNA damage response and cell proliferation in a dose-dependent manner through a number of signaling pathways involved in cell proliferation, apoptosis and se [...]
2900026A02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000148442Uncharacterized protein KIAA1671.
Kbtbd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148445Kelch repeat and BTB domain-containing protein 3.
Cdh16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148478Cadherin-16; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the [...]
Mau2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148479MAU2 chromatid cohesion factor homolog; Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodim. eric complex (also known as cohesin loading complex) with NIPBL [...]
Ces5a protein networkhttps://string-db.org/network/10090.ENSMUSP00000148481Carboxylesterase 5A; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family.
Capn15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148486Calpain-15; Belongs to the peptidase C2 family.
Vamp9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148490Vesicle-associated membrane protein 9.
Iqcm protein networkhttps://string-db.org/network/10090.ENSMUSP00000148495IQ motif-containing M.
Sipa1l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148536Signal-induced proliferation-associated 1-like protein 2.
Gnao1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148550Guanine nucleotide-binding protein G(o) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Stimu [...]
Dnmbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000148582Dynamin-binding protein; Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. R [...]
Zfp930 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148587Zinc finger protein 930.
Olfr160 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148600Olfactory receptor 151; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr857 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148617Olfactory receptor.
Adh6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000148627Alcohol dehydrogenase 6B (class V).
Mroh3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148632Maestro heat-like repeat family member 3.
Cfap54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148636Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.
Alkbh8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148653Alkylated DNA repair protein alkB homolog 8; Catalyzes the methylation of 5-carboxymethyl uridine to 5- methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its me [...]
Gm31371 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148655Predicted gene, 31371.
Nlrc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148677Protein NLRC5; Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of in [...]
Zfp853 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148683Zinc finger protein 853.
Sntb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148684Beta-2-syntrophin; Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and th [...]
Mast3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148686Microtubule-associated serine/threonine-protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Gm3045 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148690Predicted gene 3045.
Nup93 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148700Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC (By similarity). During [...]
Zfp612 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148717Zinc finger protein 612.
Mup22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148722Major urinary protein 22; Belongs to the calycin superfamily. Lipocalin family.
Iqcn protein networkhttps://string-db.org/network/10090.ENSMUSP00000148728IQ motif-containing N.
Rfxank protein networkhttps://string-db.org/network/10090.ENSMUSP00000148739DNA-binding protein RFXANK; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. R [...]
Rnf212 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148758Probable E3 SUMO-protein ligase RNF212; SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific reco [...]
Nmur1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148767Neuromedin-U receptor 1; Receptor for the neuromedin-U and neuromedin-S neuropeptides.
Ralyl protein networkhttps://string-db.org/network/10090.ENSMUSP00000148795RNA-binding Raly-like protein.
Msantd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148805Myb/SANT-like DNA-binding domain-containing protein 4.
Cnot1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148807CCR4-NOT transcription complex subunit 1; Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including [...]
Gimd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148832GTPase IMAP family member GIMD1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
Olfr1419 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148848Olfactory receptor.
Olfr1274 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148849Olfactory receptor.
Olfr971 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148850Olfactory receptor.
Olfr828 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148853Olfactory receptor.
Olfr772 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148854Olfactory receptor.
Olfr1182 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148855Olfactory receptor.
Olfr8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148856Olfactory receptor 8; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1454 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148859Olfactory receptor.
Olfr1565 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148860Olfactory receptor.
Olfr1046 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148873Olfactory receptor.
Olfr107 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148879Olfactory receptor.
Olfr1313 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148886Olfactory receptor.
Olfr907 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148894Olfactory receptor.
Olfr99 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148900Olfactory receptor.
Olfr1094 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148902Olfactory receptor 1094; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr979 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148903Olfactory receptor MOR223-1.
Olfr124 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148904Olfactory receptor.
Olfr30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148907Olfactory receptor.
Olfr889 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148913Olfactory receptor 889.
Olfr811 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148915Olfactory receptor.
Olfr740 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148916Olfactory receptor.
Olfr666 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148919Olfactory receptor.
Olfr178 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148922Olfactory receptor.
Olfr1286 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148932Olfactory receptor.
Olfr1138 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148941Olfactory receptor.
Olfr801 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148943Olfactory receptor.
Olfr1505 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148945Olfactory receptor.
Olfr1015 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148957Olfactory receptor.
Olfr59 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148959Olfactory receptor.
Olfr729 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148960Olfactory receptor.
Olfr642 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148961Olfactory receptor.
Olfr571 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148964Olfactory receptor 571.
Ackr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148966Atypical chemokine receptor 2; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal [...]
Olfr600 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148967Olfactory receptor.
Olfr968 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148969Olfactory receptor.
Olfr1045 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148982Olfactory receptor.
Olfr732 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148984Olfactory receptor.
Olfr963 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148985Olfactory receptor Olfr963.
Olfr1339 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148988Olfactory receptor MOR258-2.
Olfr190 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148991Olfactory receptor.
Olfr390 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148992Olfactory receptor.
Olfr577 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148993Olfactory receptor.
Olfr156 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148995Olfactory receptor.
Olfr384 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148997Olfactory receptor.
Olfr139 protein networkhttps://string-db.org/network/10090.ENSMUSP00000148999Olfactory receptor 139; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr609 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149003Olfactory receptor 609.
Olfr433 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149005Olfactory receptor.
Olfr769 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149008Olfactory receptor.
Olfr446 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149013Olfactory receptor.
Olfr76 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149014Olfactory receptor.
Olfr1303 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149015Olfactory receptor.
Olfr711 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149016Olfactory receptor.
Olfr31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149019Olfactory receptor.
Usp44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149020Ubiquitin carboxyl-terminal hydrolase 44; Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by [...]
Olfr703 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149022Olfactory receptor MOR283-7.
Olfr1271 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149028Olfactory receptor.
Olfr1389 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149032Olfactory receptor.
Olfr851 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149033Olfactory receptor.
Olfr235 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149035Olfactory receptor.
Olfr299 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149038Olfactory receptor Olfr299.
Olfr556 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149041Olfactory receptor.
Olfr810 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149044Olfactory receptor.
Olfr617 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149045Olfactory receptor.
Olfr648 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149047Olfactory receptor.
Olfr1214 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149049Olfactory receptor.
Olfr420 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149052Olfactory receptor.
Olfr318 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149053Olfactory receptor.
Olfr922 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149057Olfactory receptor.
Olfr66 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149058Olfactory receptor.
Olfr479 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149060Olfactory receptor Olfr479.
Olfr229 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149063Olfactory receptor.
Olfr395 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149064Olfactory receptor.
Olfr339 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149068Olfactory receptor.
Olfr644 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149070Olfactory receptor.
Olfr1491 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149071Olfactory receptor.
Olfr1249 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149072Olfactory receptor.
Olfr330 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149073Olfactory receptor.
Pomgnt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149077Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2; O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the m [...]
Olfr1154 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149078Olfactory receptor.
Olfr527 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149080Olfactory receptor Olfr527.
Olfr747 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149081Olfactory receptor.
Olfr569 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149088Olfactory receptor.
Olfr1106 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149092Olfactory receptor.
Olfr1213 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149096Olfactory receptor.
Olfr1166 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149099Olfactory receptor.
Olfr1196 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149100Olfactory receptor.
Olfr646 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149102Olfactory receptor.
Olfr633 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149105Olfactory receptor.
Olfr724 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149110Olfactory receptor.
Olfr699 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149112Olfactory receptor Olfr699.
Olfr611 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149114Olfactory receptor.
Olfr806 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149115Olfactory receptor.
Olfr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149118Olfactory receptor 3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr826 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149119Olfactory receptor.
Olfr1377 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149125Olfactory receptor.
Olfr1264 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149126Olfactory receptor.
Mbd3l2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149130Methyl-CpG-binding domain protein 3-like 2.
Olfr127 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149133Olfactory receptor.
Olfr715b protein networkhttps://string-db.org/network/10090.ENSMUSP00000149136Olfactory receptor 715B.
Olfr1023 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149138Olfactory receptor.
Olfr1417 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149141Olfactory receptor.
Olfr1497 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149151Olfactory receptor.
Dock6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149156Dedicator of cytokinesis protein 6; Acts as guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases (By similarity). Through its activation of CDC42 and RAC1, regulates neurite [...]
Olfr516 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149160Olfactory receptor.
Olfr259 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149161Olfactory receptor.
Olfr744 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149164Olfactory receptor.
Olfr102 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149168Olfactory receptor.
Olfr398 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149170Olfactory receptor MOR157-1.
Olfr1218 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149171Olfactory receptor.
Olfr807 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149172Olfactory receptor MOR117-1.
Olfr572 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149174Olfactory receptor MOR10-2.
Olfr1384 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149183Olfactory receptor.
Olfr596 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149187Olfactory receptor.
Olfr1448 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149191Olfactory receptor.
Olfr653 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149192Olfactory receptor.
Olfr935 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149193Olfactory receptor.
Olfr1446 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149198Olfactory receptor.
Olfr598 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149199Olfactory receptor.
Olfr827 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149200Olfactory receptor.
Olfr1420 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149208Olfactory receptor.
Olfr578 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149209Olfactory receptor.
Arfgef3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149210Brefeldin A-inhibited guanine nucleotide-exchange protein 3; Participates in the regulation of systemic glucose homeostasis, where it negatively regulates insulin granule biogenesis in pancreatic [...]
Olfr110 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149213Olfactory receptor.
Csrnp1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149214Cysteine/serine-rich nuclear protein 1; Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May have a tumor-suppressor function. May play a role in apoptosis [...]
Olfr1305 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149215Olfactory receptor.
Olfr1513 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149216Olfactory receptor 1513.
Olfr1449 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149217Olfactory receptor.
Olfr1055 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149219Olfactory receptor.
Olfr1340 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149224Olfactory receptor 1340.
Olfr1031 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149225Olfactory receptor.
Olfr930 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149230Olfactory receptor MOR171-46.
Olfr361 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149234Olfactory receptor.
Olfr533 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149238Olfactory receptor Olfr533.
Olfr1104 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149240Olfactory receptor.
Olfr1351 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149241Olfactory receptor MOR139-4.
Olfr1065 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149248Olfactory receptor.
Olfr16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149249Olfactory receptor Olfr16.
Gm34653 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149256Hexosyltransferase.
Olfr429 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149257Olfactory receptor.
Olfr780 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149258Olfactory receptor.
Olfr818 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149259Olfactory receptor.
Olfr237 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149261Olfactory receptor.
Olfr910 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149263Olfactory receptor.
Olfr464 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149264Olfactory receptor.
Olfr78 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149274Olfactory receptor 51E2; Olfactory receptor. The activity of this receptor is propably mediated by G-proteins wich induce elevation of intracellular Ca(2+), cAMP and activation of phosphorylation [...]
Olfr183 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149279Olfactory receptor 183; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr599 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149281Olfactory receptor.
Olfr1323 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149286Olfactory receptor.
Olfr372 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149288Olfactory receptor.
Olfr933 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149292Olfactory receptor.
Olfr385 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149293Olfactory receptor.
Olfr146 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149294Olfactory receptor 146; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr467 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149295Olfactory receptor.
Olfr354 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149298Olfactory receptor.
Olfr1299 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149299Olfactory receptor.
Olfr1234 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149303Olfactory receptor.
Olfr698 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149305Olfactory receptor Olfr698.
Olfr45 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149309Olfactory receptor.
Olfr1137 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149311Olfactory receptor.
Olfr1233 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149322Olfactory receptor.
Olfr447 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149325Olfactory receptor.
Olfr129 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149327Olfactory receptor.
Olfr466 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149328Olfactory receptor.
Olfr1221 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149330Olfactory receptor.
Olfr992 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149333Olfactory receptor.
Olfr122 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149334Olfactory receptor.
Ncoa7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149335Nuclear receptor coactivator 7; Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RA [...]
Olfr157 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149336Olfactory receptor.
Olfr272 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149339Olfactory receptor.
Olfr535 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149340Olfactory receptor.
Olfr1370 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149341Olfactory receptor.
Olfr1052 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149344Olfactory receptor 1052; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr368 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149348Olfactory receptor.
Smim38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149353Small integral membrane protein 38.
Olfr784 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149354Olfactory receptor.
Olfr381 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149355Olfactory receptor.
Olfr1393 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149358Olfactory receptor.
Olfr1049 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149360Olfactory receptor.
Olfr525 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149361Olfactory receptor.
Olfr1242 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149368Olfactory receptor.
Olfr351 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149369Olfactory receptor.
Olfr985 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149371Olfactory receptor.
Olfr353 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149378Olfactory receptor.
Olfr194 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149379Olfactory receptor.
Olfr787 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149391Olfactory receptor.
Olfr1447 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149392Olfactory receptor.
Olfr731 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149395Olfactory receptor.
Olfr1163 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149399Olfactory receptor.
Olfr1122 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149403Olfactory receptor.
Olfr168 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149405Olfactory receptor.
Olfr487 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149407Olfactory receptor Olfr487.
Olfr290-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149411Olfactory receptor 290.
Olfr205 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149415Olfactory receptor.
Olfr303 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149419Olfactory receptor.
Scn11a protein networkhttps://string-db.org/network/10090.ENSMUSP00000149420Sodium channel protein type 11 subunit alpha; This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to th [...]
Olfr948 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149422Olfactory receptor.
Olfr1360 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149423Olfactory receptor.
Olfr1155 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149428Olfactory receptor MOR174-10.
Olfr1378 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149432Olfactory receptor.
Olfr981 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149436Olfactory receptor MOR223-8.
Olfr1148 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149438Olfactory receptor.
Olfr1087 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149439Olfactory receptor.
Olfr513 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149440Olfactory receptor.
Olfr1216 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149441Olfactory receptor.
Olfr1195 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149442Olfactory receptor.
Olfr228 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149449Olfactory receptor.
Olfr133 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149451Olfactory receptor.
Olfr458 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149459Olfactory receptor.
Olfr1133 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149460Olfactory receptor Olfr1133.
Olfr1321 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149462Olfactory receptor.
Senp8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149463Sentrin-specific protease 8; Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted prot [...]
Olfr1243 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149464Olfactory receptor.
Olfr1341 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149466Olfactory receptor Olfr1341.
Olfr73 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149472Olfactory receptor.
Olfr530 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149475Olfactory receptor MOR252-2.
Olfr1511 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149479Olfactory receptor 1511.
Olfr799 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149485Olfactory receptor.
Olfr1467 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149487Olfactory receptor.
Olfr748 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149491Olfactory receptor.
Olfr510 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149492Olfactory receptor 510; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr805 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149493Olfactory receptor.
Olfr1110 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149495Olfactory receptor.
Siae protein networkhttps://string-db.org/network/10090.ENSMUSP00000149505Sialate O-acetylesterase large subunit; Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid.
Cxcr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149508C-X-C chemokine receptor type 5; Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into th [...]
Olfr1089 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149509Olfactory receptor 1089.
Olfr419 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149512Olfactory receptor.
Olfr816 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149515Olfactory receptor.
Olfr1168 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149517Olfactory receptor.
Olfr1394 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149520Olfactory receptor.
Olfr394 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149527Olfactory receptor.
Olfr1099 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149528Olfactory receptor.
AI593442 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149532Uncharacterized protein C11orf87 homolog.
Olfr550 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149536Olfactory receptor.
Olfr401 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149542Olfactory receptor.
Olfr90 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149544Olfactory receptor.
Olfr1056 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149545Olfactory receptor.
Olfr1258 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149547Olfactory receptor.
Olfr1368 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149549Olfactory receptor.
Olfr969 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149551Olfactory receptor.
Olfr957 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149559Olfactory receptor.
Olfr1477 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149565Olfactory receptor.
Olfr352 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149568Olfactory receptor.
Olfr427 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149570Olfactory receptor.
Olfr1219 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149573Olfactory receptor.
Olfr1416 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149576Olfactory receptor.
Olfr606 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149577Olfactory receptor.
Olfr916 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149578Olfactory receptor.
Olfr360 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149581Olfactory receptor.
Olfr1199 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149586Olfactory receptor.
Olfr33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149588Olfactory receptor.
Olfr1535 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149589Olfactory receptor.
Olfr293 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149592Olfactory receptor Olfr293.
Olfr132 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149593Olfactory receptor.
Olfr632 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149598Olfactory receptor Olfr632.
Olfr1167 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149599Olfactory receptor.
Olfr130 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149601Olfactory receptor.
Olfr125 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149602Olfactory receptor.
Olfr101 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149603Olfactory receptor.
Olfr1173 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149617Olfactory receptor.
Olfr1410 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149621Olfactory receptor.
Olfr1532-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149624Olfactory receptor.
Olfr974 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149630Olfactory receptor MOR171-1.
Olfr1016 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149631Olfactory receptor.
Olfr1102 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149634Olfactory receptor 1102; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1278 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149635Olfactory receptor.
Olfr720 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149641Olfactory receptor.
Olfr50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149648Olfactory receptor 50; Odorant receptor. Activated by (+) and (-)-carvone. Belongs to the G-protein coupled receptor 1 family.
Olfr1184 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149649Olfactory receptor.
Olfr1259 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149652Olfactory receptor.
Olfr91 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149656Olfactory receptor.
Olfr509 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149663Olfactory receptor MOR267-14.
Olfr149 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149664Olfactory receptor 149; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr350 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149667Olfactory receptor.
Olfr434 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149678Olfactory receptor.
Cck protein networkhttps://string-db.org/network/10090.ENSMUSP00000149679Cholecystokinin-12; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stim [...]
Olfr1132 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149683Olfactory receptor.
Olfr1265 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149684Olfactory receptor.
Olfr62 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149687Olfactory receptor 62.
Olfr1208 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149695Olfactory receptor.
Olfr1189 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149696Olfactory receptor.
Olfr312 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149697Olfactory receptor.
Olfr1310 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149701Olfactory receptor.
Olfr24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149702Olfactory receptor 24; Odorant receptor.
Olfr672 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149704Olfactory receptor.
Olfr1140 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149706Olfactory receptor.
Olfr1489 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149711Olfactory receptor.
Olfr1402 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149714Olfactory receptor.
Olfr1043 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149716Olfactory receptor.
Olfr1512 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149717Olfactory receptor MOR223-5.
Olfr1250 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149720Olfactory receptor.
Olfr10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149724Olfactory receptor 10; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr71 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149725Olfactory receptor.
Olfr38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149726Olfactory receptor.
Olfr357 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149727Olfactory receptor.
Gm4894 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149729Predicted gene, EG235327.
Olfr1275 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149730Olfactory receptor.
Olfr389 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149734Olfactory receptor.
Olfr114 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149735Olfactory receptor.
Olfr113 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149739Olfactory receptor.
Olfr1062 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149742Olfactory receptor.
Olfr639 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149743Olfactory receptor.
Ubl7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149748Ubiquitin-like protein 7.
Olfr342 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149751Olfactory receptor.
Olfr1200 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149757Olfactory receptor.
Olfr536 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149758Olfactory receptor MOR252-1.
Olfr476 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149760Olfactory receptor 476; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr305 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149762Olfactory receptor.
Olfr463 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149765Olfactory receptor 463.
Olfr849 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149769Olfactory receptor.
Olfr695 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149773Olfactory receptor MOR283-6.
Olfr307 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149779Olfactory receptor.
Olfr1212 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149781Olfactory receptor.
Olfr1427 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149787Olfactory receptor.
Olfr958 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149788Olfactory receptor 958; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr728 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149796Olfactory receptor.
Olfr934 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149799Olfactory receptor MOR224-6.
Cryab protein networkhttps://string-db.org/network/10090.ENSMUSP00000149803Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress [...]
Olfr733 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149807Olfactory receptor.
Olfr222 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149821Olfactory receptor.
Olfr1039 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149830Olfactory receptor.
Tipin protein networkhttps://string-db.org/network/10090.ENSMUSP00000149833TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replicat [...]
Olfr49 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149840Olfactory receptor 49; Odorant receptor. Activated by (-)-citronellal and to a lesser extent by (+)-citronellal. Not activated by carvone or limonene. Belongs to the G-protein coupled receptor 1 [...]
Olfr1198 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149844Olfactory receptor.
Olfr594 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149847Olfactory receptor.
Olfr924 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149849Olfactory receptor.
Olfr373 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149853Olfactory receptor.
Olfr153 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149859Olfactory receptor.
Olfr1458 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149865Olfactory receptor.
Olfr641 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149866Olfactory receptor.
Olfr1006 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149868Olfactory receptor.
Olfr792 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149872Olfactory receptor.
Olfr1251 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149873Olfactory receptor.
Hinfp protein networkhttps://string-db.org/network/10090.ENSMUSP00000149879Histone H4 transcription factor; Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene tra [...]
Olfr1381 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149881Olfactory receptor.
Adpgk protein networkhttps://string-db.org/network/10090.ENSMUSP00000149882ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency; Belongs [...]
Olfr727 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149886Olfactory receptor.
Olfr1263 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149887Olfactory receptor MOR234-2.
Olfr677 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149888Olfactory receptor.
Olfr263 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149892Olfactory receptor.
Olfr13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149893Olfactory receptor 13; Odorant receptor.
Olfr126 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149896Olfactory receptor.
Olfr266 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149899Olfactory receptor.
Olfr553 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149901Olfactory receptor Olfr553.
Olfr203 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149906Olfactory receptor.
Olfr837 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149907Olfactory receptor.
Olfr1120 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149911Olfactory receptor.
Olfr1241 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149914Olfactory receptor.
Olfr346 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149916Olfactory receptor.
Olfr399 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149917Olfactory receptor.
Tex12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149921Testis-expressed protein 12.
Olfr412 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149922Olfactory receptor.
Olfr459 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149928Olfactory receptor.
Olfr1206 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149929Olfactory receptor.
Olfr876 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149930Olfactory receptor.
Olfr1217 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149931Olfactory receptor.
Gnb5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149938Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the s [...]
Olfr659 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149939Olfactory receptor.
Olfr531 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149942Olfactory receptor MOR251-3.
Olfr1176 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149943Olfactory receptor MOR174-5.
Olfr1093 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149944Olfactory receptor.
Olfr1012 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149946Olfactory receptor.
Olfr995 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149952Olfactory receptor.
Atr protein networkhttps://string-db.org/network/10090.ENSMUSP00000149953Serine/threonine-protein kinase ATR; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA r [...]
Olfr1112 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149960Olfactory receptor.
Olfr1364 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149964Olfactory receptor.
Olfr1342 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149966Olfactory receptor MOR258-3.
Olfr164 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149971Olfactory receptor.
Olfr411 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149978Olfactory receptor.
Olfr825 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149981Olfactory receptor.
Olfr845 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149986Olfactory receptor.
Olfr1487 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149988Olfactory receptor.
Olfr223 protein networkhttps://string-db.org/network/10090.ENSMUSP00000149991Olfactory receptor.
Olfr1469 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150006Olfactory receptor.
Olfr843 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150008Olfactory receptor.
Olfr27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150009Olfactory receptor.
Olfr912 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150014Olfactory receptor.
Olfr1509 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150016Olfactory receptor 1509; Olfactory receptor that is activated by the binding of organosulfur odorants with thioether groups such as (methylthio)methanethiol (MTMT) and bis(methylthiomethyl) disul [...]
Olfr1484 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150019Olfactory receptor.
Olfr150 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150024Olfactory receptor 150; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr317 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150027Olfactory receptor.
Olfr393 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150031Olfactory receptor.
Olfr1385 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150035Olfactory receptor.
Olfr1178 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150036Olfactory receptor.
Olfr320 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150051Olfactory receptor.
Olfr904 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150057Olfactory receptor.
Olfr52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150060Olfactory receptor.
Olfr1051 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150061Olfactory receptor.
Olfr738 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150067Olfactory receptor.
Olfr657 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150070Olfactory receptor Olfr657.
Olfr1317 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150073Olfactory receptor.
Olfr706 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150075Olfactory receptor MOR283-11.
Olfr1135 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150079Olfactory receptor.
Olfr870 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150084Olfactory receptor.
Olfr328 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150086Olfactory receptor.
Olfr874 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150088Olfactory receptor.
Olfr1086 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150094Olfactory receptor 1086; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1428 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150097Olfactory receptor.
Olfr119 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150099Olfactory receptor.
Olfr167 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150102Olfactory receptor.
Olfr1359 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150106Olfactory receptor.
Olfr684 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150107Olfactory receptor Olfr684.
Olfr1204 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150111Olfactory receptor.
Olfr1248 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150117Olfactory receptor 1248.
Olfr1121 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150120Olfactory receptor.
Smco4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150121Single-pass membrane and coiled-coil domain-containing protein 4.
Olfr1348 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150128Olfactory receptor.
Ankdd1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000150130Ankyrin repeat and death domain-containing 1A.
Olfr804 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150132Olfactory receptor.
Olfr1107 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150135Olfactory receptor.
Olfr623 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150141Olfactory receptor.
Olfr1170 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150142Olfactory receptor.
Olfr1222 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150144Olfactory receptor.
Olfr1418 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150146Olfactory receptor.
Olfr1382 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150149Olfactory receptor.
Olfr1034 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150150Olfactory receptor.
Olfr767 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150151Olfactory receptor.
Olfr1109 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150159Olfactory receptor.
Olfr1388 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150160Olfactory receptor.
Olfr1336 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150162Olfactory receptor.
Gm49337 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150163Predicted gene, 49337.
Olfr615 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150166Olfactory receptor.
Olfr715 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150168Olfactory receptor MOR260-1.
Olfr616 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150171Olfactory receptor.
Olfr397 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150172Olfactory receptor.
Olfr137 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150173Olfactory receptor.
Olfr716 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150175Olfactory receptor.
Olfr462 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150179Olfactory receptor 462.
Olfr750 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150180Olfactory receptor.
Olfr967 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150183Olfactory receptor.
Olfr1044 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150199Olfactory receptor 1044; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1013 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150201Olfactory receptor 1013; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr175 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150202Olfactory receptor.
Olfr693 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150203Olfactory receptor MOR283-8.
Olfr117 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150204Olfactory receptor.
Olfr1495 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150205Olfactory receptor.
Olfr1205 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150206Olfactory receptor.
Olfr1444 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150212Olfactory receptor 1444; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr678 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150213Olfactory receptor.
Olfr1226 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150215Olfactory receptor.
Olfr142 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150216Olfactory receptor 142; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr694 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150217Olfactory receptor 694.
Olfr855 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150218Olfactory receptor.
Olfr1115 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150221Olfactory receptor.
Gm3776 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150224Glutathione S-transferase.
Olfr1239 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150225Olfactory receptor.
Olfr298 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150228Olfactory receptor Olfr298.
Olfr665 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150229Olfactory receptor.
Olfr545 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150232Olfactory receptor.
Olfr597 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150238Olfactory receptor.
Olfr914 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150241Olfactory receptor.
Olfr1450 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150243Olfactory receptor.
Olfr1124 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150244Olfactory receptor.
Olfr32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150246Olfactory receptor.
Olfr1047 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150247Olfactory receptor.
Olfr195 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150249Olfactory receptor.
Olfr1161 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150251Olfactory receptor.
Olfr1411 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150254Olfactory receptor.
Olfr1240 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150256Olfactory receptor.
Olfr1090 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150257Olfactory receptor.
Olfr1085 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150258Olfactory receptor.
Olfr224 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150268Olfactory receptor.
Olfr177 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150269Olfactory receptor.
Inafm2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150273InaF motif-containing 2.
Olfr937 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150274Olfactory receptor.
Cyp1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150277Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molec [...]
Olfr1020 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150285Olfactory receptor 1020; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1197 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150290Olfactory receptor.
Olfr410 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150291Olfactory receptor.
Olfr1510 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150294Olfactory receptor 1510.
Olfr691 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150297Olfactory receptor.
Olfr58 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150309Olfactory receptor.
Olfr1231 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150310Olfactory receptor.
Olfr554 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150312Olfactory receptor 554.
Olfr1361 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150315Olfactory receptor.
Olfr552 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150317Olfactory receptor.
Parp16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150318Protein mono-ADP-ribosyltransferase PARP16; Intracellular mono-ADP-ribosyltransferase that may play a role in different processes through the mono-ADP-ribosylation of proteins involved in those p [...]
Olfr1037 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150319Olfactory receptor.
Olfr700 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150320Olfactory receptor MOR283-4.
Olfr63 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150323Olfactory receptor 63; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr970 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150325Olfactory receptor.
Olfr109 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150326Olfactory receptor.
Olfr243 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150329Olfactory receptor.
Olfr1499 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150330Olfactory receptor.
Olfr1288 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150331Olfactory receptor.
Olfr667 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150340Olfactory receptor.
Olfr775 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150345Olfactory receptor.
Olfr283 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150348Olfactory receptor.
Olfr959 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150349Olfactory receptor MOR224-3.
Olfr1014 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150352Olfactory receptor.
Tyk2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150354Non-receptor tyrosine-protein kinase TYK2; Involved in intracellular signal transduction by amplifying type I and type II IFN signaling. Phosphorylates the interferon- alpha/beta receptor alpha c [...]
Olfr905 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150357Olfactory receptor.
Olfr186 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150366Olfactory receptor 186; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1238 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150367Olfactory receptor.
Olfr549 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150373Olfactory receptor.
Olfr1354 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150374Olfactory receptor.
Olfr295 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150377Olfactory receptor Olfr295.
Olfr867 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150378Olfactory receptor 867; Possible olfactory or taste receptor. Belongs to the G-protein coupled receptor 1 family.
Olfr655 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150381Olfactory receptor 655.
Olfr1290 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150388Olfactory receptor.
Olfr972 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150389Olfactory receptor.
Olfr622 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150390Olfactory receptor.
Olfr308 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150391Olfactory receptor.
Olfr709-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150392Olfactory receptor.
Olfr965 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150401Olfactory receptor.
Olfr472 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150404Olfactory receptor 472; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1002 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150405Olfactory receptor 1002; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1312 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150415Olfactory receptor.
Olfr448 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150419Olfactory receptor.
Olfr418 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150427Olfactory receptor 418.
Olfr140 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150438Olfactory receptor 140; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr497 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150439Olfactory receptor 497; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr911-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150446Olfactory receptor.
Olfr1009 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150450Olfactory receptor 1009; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr430 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150451Olfactory receptor.
Olfr1201 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150454Olfactory receptor.
Olfr814 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150458Olfactory receptor.
Cx3cr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150463CX3C chemokine receptor 1; Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions.
Olfr820 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150464Olfactory receptor.
Olfr453 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150467Olfactory receptor.
Olfr1269 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150470Olfactory receptor.
Olfr944 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150471Olfactory receptor.
Olfr191 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150473Olfactory receptor.
Olfr141 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150485Olfactory receptor 141; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr469 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150486Olfactory receptor 469; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr68 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150493Olfactory receptor.
Olfr980 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150496Olfactory receptor MOR223-2.
Olfr791 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150497Olfactory receptor.
Olfr1080 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150502Olfactory receptor.
Olfr1346 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150503Olfactory receptor MOR103-6.
Olfr1126 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150504Olfactory receptor.
Olfr48 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150505Olfactory receptor.
Olfr901 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150506Olfactory receptor Olfr901.
Olfr1283 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150510Olfactory receptor.
Olfr55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150511Olfactory receptor 55.
Olfr1322 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150512Olfactory receptor.
Mrln protein networkhttps://string-db.org/network/10090.ENSMUSP00000150523Myoregulin; Inhibits the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+), thereby acting as a key regulator of skeletal mus [...]
Olfr612 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150524Olfactory receptor.
Olfr1392 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150526Olfactory receptor.
Olfr313 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150529Olfactory receptor.
Olfr281 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150530Olfactory receptor.
Olfr796 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150534Olfactory receptor.
Olfr135 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150535Olfactory receptor.
Olfr1229 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150537Olfactory receptor.
Colca2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150539COLCA2 homolog.
Inpp4b protein networkhttps://string-db.org/network/10090.ENSMUSP00000150541Type II inositol 3,4-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-bisph [...]
Olfr348 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150542Olfactory receptor.
Olfr1297 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150543Olfactory receptor.
Olfr984 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150545Olfactory receptor MOR239-6.
Olfr1084 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150546Olfactory receptor 1084.
Olfr1223 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150550Olfactory receptor.
Olfr1320 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150556Olfactory receptor.
Olfr739 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150559Olfactory receptor.
Olfr131 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150562Olfactory receptor.
Dcun1d5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150564DCN1-like protein 5.
Olfr1211 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150571Olfactory receptor.
Olfr441 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150572Olfactory receptor.
Olfr551 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150582Olfactory receptor.
Olfr111 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150585Olfactory receptor.
Olfr23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150593Olfactory receptor.
Olfr608 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150595Olfactory receptor.
Olfr432 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150596Olfactory receptor.
Olfr726 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150599Olfactory receptor.
Olfr477 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150605Olfactory receptor 477; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1209 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150607Olfactory receptor.
Olfr366 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150608Olfactory receptor.
Olfr473 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150610Olfactory receptor 473; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr736 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150611Olfactory receptor.
Olfr1311 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150617Olfactory receptor.
Fignl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150618Fidgetin-like 2.
Olfr987 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150619Olfactory receptor.
Olfr557 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150621Olfactory receptor.
Olfr1019 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150622Olfactory receptor 1019; Olfactory receptor that is activated by the binding of organosulfur odorants with thioether groups such as (methylthio)methanethiol (MTMT). The activity of this receptor [...]
Olfr1057 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150623Olfactory receptor.
Olfr749 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150627Olfactory receptor.
Olfr619 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150630Olfactory receptor.
Olfr461 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150632Olfactory receptor.
Olfr1391 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150635Olfactory receptor.
Olfr1029 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150637Olfactory receptor.
Olfr199 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150643Olfactory receptor.
Olfr1423 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150649Olfactory receptor.
Olfr822 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150652Olfactory receptor.
Olfr776 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150656Olfactory receptor.
Olfr201 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150660Olfactory receptor.
Olfr824 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150662Olfactory receptor.
Olfr975 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150664Olfactory receptor MOR224-2.
Olfr679 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150668Olfactory receptor MOR40-2.
Olfr846 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150672Olfactory receptor.
Olfr221 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150675Olfactory receptor.
Olfr1395 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150679Olfactory receptor MOR277-1.
Olfr875 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150684Olfactory receptor.
Olfr60 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150685Olfactory receptor.
Olfr629 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150688Olfactory receptor.
Olfr495 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150689Olfactory receptor 495; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1440 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150691Olfactory receptor 1440; Odorant receptor involved in the detection of muscone.
Olfr491 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150694Olfactory receptor 491; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr877 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150698Olfactory receptor.
Cdkn2d protein networkhttps://string-db.org/network/10090.ENSMUSP00000150701Cyclin-dependent kinase 4 inhibitor D; Interacts strongly with CDK4 and CDK6 and inhibits them.
Olfr1277 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150703Olfactory receptor.
Olfr1082 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150706Olfactory receptor.
Olfr1261 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150711Olfactory receptor.
Olfr998 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150713Olfactory receptor 998; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Robo4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150722Roundabout homolog 4; Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migr [...]
Olfr765 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150725Olfactory receptor.
Olfr1000 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150731Olfactory receptor.
Olfr734 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150732Olfactory receptor.
Olfr681 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150733Olfactory receptor 681.
Olfr214 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150737Olfactory receptor MOR119-1.
Olfr1441 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150739Olfactory receptor.
Olfr1272 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150745Olfactory receptor.
Olfr686 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150746Olfactory receptor.
Olfr1471 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150749Olfactory receptor.
Olfr1131 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150754Olfactory receptor.
Olfr482 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150755Olfactory receptor 482; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150757Olfactory receptor 15; Olfactory receptor that is activated by the binding of organosulfur odorants with thioether groups such as (methylthio)methanetiol (MTMT). Also binds odorants acetophenone [...]
Olfr1111 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150760Olfactory receptor.
Olfr148 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150761Olfactory receptor 148; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr166 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150764Olfactory receptor.
Olfr853 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150773Olfactory receptor.
Olfr484 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150774Olfactory receptor 484; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr651 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150776Olfactory receptor.
Olfr123 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150780Olfactory receptor.
Olfr358 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150781Olfactory receptor.
Olfr285 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150788Olfactory receptor.
Olfr1245 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150791Olfactory receptor.
Olfr1413 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150792Olfactory receptor.
Olfr823 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150794Olfactory receptor.
Olfr532 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150798Olfactory receptor.
Olfr341 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150801Olfactory receptor.
Olfr406 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150802Olfactory receptor.
Olfr54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150809Olfactory receptor.
Olfr1054 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150810Olfactory receptor.
Olfr1220 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150812Olfactory receptor.
Olfr742 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150814Olfactory receptor.
Olfr218 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150815Olfactory receptor 218.
Nme9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150820NME/NM23 family member 9; Belongs to the NDK family.
Thyn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150823Thymocyte nuclear protein 1; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
Olfr668 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150824Olfactory receptor.
Olfr161 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150825Olfactory receptor.
Olfr1186 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150826Olfactory receptor.
Olfr690 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150831Olfactory receptor.
Olfr1134 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150837Olfactory receptor.
Olfr424 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150840Olfactory receptor.
Slc37a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150843Solute carrier family 37 (Glucose-6-phosphate transporter), member 4.
Olfr921 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150844Olfactory receptor.
Olfr267 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150848Olfactory receptor.
Olfr279 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150851Olfactory receptor.
Olfr362 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150852Olfactory receptor.
Olfr705 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150853Olfactory receptor 705.
Gm13723 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150854Olfactory receptor.
Olfr12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150858Olfactory receptor 12; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1232 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150860Olfactory receptor.
Olfr311 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150870Olfactory receptor.
Olfr1246 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150876Olfactory receptor.
Olfr239 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150882Olfactory receptor 239.
Olfr319 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150883Olfactory receptor.
Olfr1459 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150886Olfactory receptor.
Olfr97 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150892Olfactory receptor.
Olfr591 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150894Olfactory receptor.
Olfr483 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150898Olfactory receptor 483; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Acp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150903Tartrate-resistant acid phosphatase type 5; May play a role in the process of bone resorption. The osteoclastic trap acts on nucleotide tri- and diphosphates with higher affinity, compared with o [...]
Olfr112 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150904Olfactory receptor.
Olfr1130 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150905Olfactory receptor.
Olfr1256 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150906Olfactory receptor.
Olfr172 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150908Olfactory receptor.
Olfr1225 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150915Olfactory receptor.
Olfr169 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150917Olfactory receptor.
Olfr610 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150921Olfactory receptor.
Olfr669 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150928Olfactory receptor.
Olfr435 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150935Olfactory receptor.
Olfr1181 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150939Olfactory receptor.
Olfr1412 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150943Olfactory receptor.
Olfr743 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150946Olfactory receptor.
Ccdc82 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150947Coiled-coil domain-containing protein 82.
Olfr782 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150951Olfactory receptor.
Olfr1457 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150957Olfactory receptor.
Olfr1396 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150961Olfactory receptor.
Olfr561 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150963Olfactory receptor.
Olfr1180 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150965Olfactory receptor.
Olfr1431 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150967Olfactory receptor.
Olfr524 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150970Olfactory receptor.
Olfr498 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150971Olfactory receptor 498; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr116 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150977Olfactory receptor.
Olfr517 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150980Olfactory receptor.
Olfr1129 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150986Olfactory receptor.
Olfr92 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150988Olfactory receptor.
Olfr322 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150990Olfactory receptor.
Olfr1113 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150991Olfactory receptor.
Olfr1026 protein networkhttps://string-db.org/network/10090.ENSMUSP00000150995Olfactory receptor.
Il18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151002Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signal [...]
Olfr51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151005Olfactory receptor.
Olfr906 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151008Olfactory receptor.
Olfr231 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151011Olfactory receptor.
Olfr1406 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151023Olfactory receptor.
Olfr1253 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151024Olfactory receptor.
Olfr391 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151029Olfactory receptor.
Olfr1252 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151036Olfactory receptor.
Olfr1058 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151037Olfactory receptor.
Olfr1380 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151039Olfactory receptor.
Olfr1152 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151045Olfactory receptor.
Olfr800 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151047Olfactory receptor.
Olfr689 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151049Olfactory receptor MOR40-3.
Olfr402 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151050Olfactory receptor.
Olfr789 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151052Olfactory receptor.
Olfr1042 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151053Olfactory receptor.
Olfr788 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151054Olfactory receptor.
Olfr47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151056Olfactory receptor.
Olfr202 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151058Olfactory receptor.
Olfr1390 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151059Olfactory receptor.
Olfr902 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151061Olfactory receptor.
Olfr128 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151065Olfactory receptor.
Olfr134 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151069Olfactory receptor.
Olfr859 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151076Olfactory receptor.
Olfr1404 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151077Olfactory receptor MOR267-2.
Ankrd49 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151079Ankyrin repeat domain-containing protein 49; May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway.
Olfr1100 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151088Olfactory receptor.
Olfr1018 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151090Olfactory receptor.
Gtf3c6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151091General transcription factor 3C polypeptide 6; Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly bi [...]
Olfr1501 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151094Olfactory receptor.
Olfr559 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151100Olfactory receptor.
Olfr1215 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151104Olfactory receptor.
Olfr1387 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151105Olfactory receptor.
Olfr714 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151106Olfactory receptor.
Olfr1151 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151107Olfactory receptor.
Olfr771 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151108Olfactory receptor.
Olfr847 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151112Olfactory receptor.
Olfr978 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151115Olfactory receptor 978.
Olfr994 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151122Olfactory receptor.
Olfr1270 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151124Olfactory receptor.
Olfr605 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151125Olfactory receptor 605.
Olfr316 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151136Olfactory receptor.
Olfr323 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151137Olfactory receptor.
Olfr670 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151138Olfactory receptor.
Olfr1306 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151142Olfactory receptor.
Olfr618 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151147Olfactory receptor.
Olfr96 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151151Olfactory receptor MOR121-1.
Olfr481 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151152Olfactory receptor 481; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1425 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151154Olfactory receptor.
Olfr282 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151156Olfactory receptor.
Olfr347 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151158Olfactory receptor.
Olfr1318 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151164Olfactory receptor.
Olfr1500 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151165Olfactory receptor.
Olfr502 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151167Olfactory receptor 502; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Olfr1349 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151168Olfactory receptor.
Olfr1101 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151171Olfactory receptor.
Olfr1179 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151174Olfactory receptor.
Olfr204 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151176Olfactory receptor.
Olfr1156 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151183Olfactory receptor.
Olfr460 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151187Olfactory receptor.
Zfp445 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151198Zinc finger protein 445; Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner [...]
Olfr344 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151202Olfactory receptor MOR136-12.
Olfr355 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151206Olfactory receptor.
Olfr661 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151208Olfactory receptor MOR40-4.
Olfr1202 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151210Olfactory receptor.
Olfr988 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151211Olfactory receptor.
Olfr118 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151212Olfactory receptor.
Olfr1335 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151219Olfactory receptor 1335.
Arid5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000151227AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Acts by form [...]
Sult3a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151228Amine sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the N-sulfonation of amines.
Gstt2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151239Glutathione S-transferase theta-2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Usp15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151244Ubiquitin carboxyl-terminal hydrolase 15; Hydrolase that removes conjugated ubiquitin from target proteins and regulates various pathways such as the TGF-beta receptor signaling, NF-kappa-B and R [...]
Olfr955 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151246Olfactory receptor.
Olfr692 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151295Olfactory receptor MOR36-1.
Olfr1281 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151304Olfactory receptor.
Rps12 protein networkhttps://string-db.org/network/10090.ENSMUSP0000015130540S ribosomal protein S12.
Cd63 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151313CD63 antigen; Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leadi [...]
Olfr1295 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151314Olfactory receptor.
Olfr1350 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151318Olfactory receptor.
Gm4303 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151319Predicted gene 4303.
Olfr603 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151321Olfactory receptor.
Olfr1426 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151331Olfactory receptor.
Rnf212b protein networkhttps://string-db.org/network/10090.ENSMUSP00000151344RING finger protein 212B.
Thap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151353THAP domain-containing protein 2.
Prf1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151354Perforin-1; Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-boun [...]
Olfr640 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151356Olfactory receptor.
Olfr108 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151360Olfactory receptor.
Olfr521 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151365Olfactory receptor.
Gm9044 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151369Predicted gene 9040.
Olfr1496 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151386Olfactory receptor.
Adamts4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151387A disintegrin and metalloproteinase with thrombospondin motifs 4; Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of [...]
Cep290 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151388Centrosomal protein of 290 kDa; Involved in early and late steps in cilia formation. Its association with CCP110 is required for inhibition of primary cilia formation by CCP110 (By similarity). M [...]
Gm9049 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151392Predicted gene 9045.
Izumo4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151397Izumo sperm-egg fusion protein 4.
Gm4305 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151398Predicted gene 4305.
Olfr746 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151399Olfactory receptor.
Hspa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151408Heat shock-related 70 kDa protein 2; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synth [...]
Olfr455 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151418Olfactory receptor.
4932415D10Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000151425RIKEN cDNA 4932415D10 gene.
Tbxa2r protein networkhttps://string-db.org/network/10090.ENSMUSP00000151447Thromboxane A2 receptor; Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G- protein that activates a phosphatidylin [...]
Cited2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151452Cbp/p300-interacting transactivator 2; Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcrip [...]
Olfr520 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151459Olfactory receptor.
Esr2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151463Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elem [...]
Gm6993 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151468Predicted gene 6993.
Olfr676 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151474Olfactory receptor.
Gm49339 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151486Predicted gene, 49339.
Olfr543 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151487Olfactory receptor.
Gm10318 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151495Predicted gene 10318.
Pomc protein networkhttps://string-db.org/network/10090.ENSMUSP00000151504Corticotropin-like intermediary peptide; [Corticotropin]: Stimulates the adrenal glands to release cortisol. [Melanocyte-stimulating hormone beta]: Increases the pigmentation of skin by increasin [...]
Olfr1366 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151506Olfactory receptor.
Gm9639 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151514Predicted gene 9639.
Gm5136 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151516Lys-63-specific deubiquitinase BRCC36-like; Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains.
Misp protein networkhttps://string-db.org/network/10090.ENSMUSP00000151529Mitotic interactor and substrate of PLK1; Plays a role in mitotic spindle orientation and mitotic progression. Regulates the distribution of dynactin at the cell cortex in a PLK1-dependent manner [...]
Olfr1033 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151539Olfactory receptor.
Olfr470 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151543Olfactory receptor 470; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
Ppfia2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151545Liprin-alpha-2; Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at speci [...]
Apon protein networkhttps://string-db.org/network/10090.ENSMUSP00000151553Apolipoprotein N.
Slc10a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151555Sodium/bile acid cotransporter; The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly depe [...]
Arhgap9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151574Rho GTPase-activating protein 9.
Zfp781 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151576Zinc finger protein 781.
Kcnc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151579Potassium voltage-gated channel subfamily C member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain. Contributes t [...]
Wdcp protein networkhttps://string-db.org/network/10090.ENSMUSP00000151585WD repeat and coiled-coil-containing protein.
Sbno2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151590Protein strawberry notch homolog 2; Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhanc [...]
Gm9040 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151606Predicted gene 9040.
Gm32802 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151607Predicted gene, 32717.
Olfr365 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151617Olfactory receptor MOR138-1.
Gja1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151620Gap junction alpha-1 protein; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connex [...]
Kantr protein networkhttps://string-db.org/network/10090.ENSMUSP00000151626Kdm5c adjacent non-coding transcript.
Stx7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151638Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking f [...]
C1s2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151642Complement C1s-B subcomponent heavy chain; C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r a [...]
Olfr329 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151648Olfactory receptor.
Olfr923 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151652Olfactory receptor.
Mindy4b-ps protein networkhttps://string-db.org/network/10090.ENSMUSP00000151654MINDY lysine 48 deubiquitinase 4B, pseudogene.
Hsd17b6 protein networkhttps://string-db.org/network/10090.ENSMUSP0000015166117-beta-hydroxysteroid dehydrogenase type 6; NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17- beta-hydroxysteroid [...]
Olfr1324 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151664Olfactory receptor.
Olfr1344 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151666Olfactory receptor.
Gm9048 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151669Predicted gene 9048.
Olfr93 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151672Olfactory receptor.
Chchd10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151675Coiled-coil-helix-coiled-coil-helix domain-containing 10.
Hamp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151677Hepcidin-2; Seems to act as a signaling molecule involved in the maintenance of iron homeostasis.
Srp54c protein networkhttps://string-db.org/network/10090.ENSMUSP00000151681Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating me [...]
Hbs1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000151689HBS1-like protein.
Olfr809 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151711Olfactory receptor.
Olfr371 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151714Olfactory receptor.
Gm9736 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151736Predicted gene 9736.
Olfr1183 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151738Olfactory receptor.
Olfr589 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151739Olfactory receptor MOR32-3.
Fgf22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151743Fibroblast growth factor 22; Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development [...]
Slc25a21 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151751Mitochondrial 2-oxodicarboxylate carrier; Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a l [...]
Krtap10-10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151758Keratin-associated protein 10-10.
Olfr790 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151759Olfactory receptor.
Olfr701 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151783Olfactory receptor MOR283-1.
Tle7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151787TLE family member 7.
Gm32717 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151792Predicted gene, 32717.
Gm3285 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151795Predicted gene 3285.
Olfr170 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151806Olfactory receptor.
Gm9508 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151808Predicted gene 9508.
Arhgap5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151809Rho GTPase-activating protein 5; GTPase-activating protein for Rho family members.
Olfr1474 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151810Olfactory receptor.
Olfr1293-ps protein networkhttps://string-db.org/network/10090.ENSMUSP00000151814Olfactory receptor.
Glipr1l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151818GLI pathogenesis-related 1-like 3; Belongs to the CRISP family.
Gm9045 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151826Predicted gene 9045.
Galnt16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151829Polypeptide N-acetylgalactosaminyltransferase 16; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threo [...]
Olfr832 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151834Olfactory receptor.
Bcl9l protein networkhttps://string-db.org/network/10090.ENSMUSP00000151837B-cell CLL/lymphoma 9-like protein; Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic tra [...]
Olfr961 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151840Olfactory receptor MOR224-5.
Rassf9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151843Ras association domain-containing protein 9; May play a role in regulating vesicuar trafficking in cells.
Olfr702 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151862Olfactory receptor.
Olfr452 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151882Olfactory receptor.
Olfr518 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151883Olfactory receptor.
Olfr450 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151908Olfactory receptor.
Cep85l protein networkhttps://string-db.org/network/10090.ENSMUSP00000151909Centrosomal protein 85-like.
Olfr213 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151916Olfactory receptor Olfr213.
Cnpy2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151918Protein canopy homolog 2; Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal [...]
Grik2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151921Glutamate receptor ionotropic, kainate 2; Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitato [...]
Prdm4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151931PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation; Belongs to the class V-like SAM-binding methyltransferase superfamily.
Gm18596 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151937Predicted gene, 18596.
Nova2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151939NOVA alternative-splicing regulator 2.
Olfr417 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151947Olfactory receptor.
Baz2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000151961Bromodomain adjacent to zinc finger domain protein 2A; Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruitin [...]
Gm9046 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151963Predicted gene 9046.
Gm5039 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151971Predicted gene 5039; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ri [...]
Nap1l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151972Nucleosome assembly protein 1-like 1; Plays a key role in the regulation of embryonic neurogenesis. Promotes the proliferation of neural progenitors and inhibits neuronal differentiation during c [...]
Olfr1280 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151980Olfactory receptor.
Apba3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151985Amyloid-beta A4 precursor protein-binding family A member 3; May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. May enhance the activity of HIF1A [...]
Olfr1276 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151987Olfactory receptor.
Olfr310 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151989Olfactory receptor 310.
Gm12248 protein networkhttps://string-db.org/network/10090.ENSMUSP00000151997Predicted gene 12248; Belongs to the sterol desaturase family.
Olfr986 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152019Olfactory receptor.
Olfr1347 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152024Olfactory receptor.
Olfr652 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152027Olfactory receptor.
Tmprss9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152034Transmembrane protease serine 9; Serase-1 and serase-2 are serine proteases that hydrolyze the peptides N-t-Boc-Gln-Ala-Arg-AMC and N-t-Boc-Gln-Gly-Arg-AMC. In contrast, N-t-Boc-Ala-Phe-Lys-AMC a [...]
Ttc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152038Tetratricopeptide repeat protein 9A; Belongs to the TTC9 family.
Olfr697 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152039Olfactory receptor MOR283-5.
Txnrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152046Thioredoxin reductase 1, cytoplasmic; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Id2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152052DNA-binding protein inhibitor ID-2; Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming he [...]
A030003K21Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000152055RIKEN cDNA A030003K21 gene.
Omd protein networkhttps://string-db.org/network/10090.ENSMUSP00000152066Osteomodulin; May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the alpha(V)beta(3)-integrin (By similarity).
Gm20075 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152074Predicted gene, 20075.
Crhbp protein networkhttps://string-db.org/network/10090.ENSMUSP00000152083Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy; Belongs to the CRF-binding protein family.
Gm2001 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152093Ubiquitin-like protein 5.
Vrk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152109Serine/threonine-protein kinase VRK1; Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragm [...]
Mdga2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152112MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions.
Gm16381 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152141Predicted gene 16381.
Nlrp4f protein networkhttps://string-db.org/network/10090.ENSMUSP00000152151NACHT, LRR and PYD domains-containing protein 4F; May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound rec [...]
Zbed3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152153Zinc finger BED domain-containing protein 3; Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin. Involved i [...]
Gm49383 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152161Predicted gene, 49383.
Ctsl protein networkhttps://string-db.org/network/10090.ENSMUSP00000152169Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subs [...]
Fam50b protein networkhttps://string-db.org/network/10090.ENSMUSP00000152187Protein FAM50B.
Platr25 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152199Pluripotency-associated transcript 25.
Rps18-ps5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152211Ribosomal protein S18, pseudogene 5; Belongs to the universal ribosomal protein uS13 family.
Eipr1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152220EARP and GARP complex-interacting protein 1; Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the t [...]
Pitrm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152229Presequence protease, mitochondrial; Metalloendopeptidase of the mitochondrial matrix that functions in peptide cleavage and degradation rather than in protein processing. Has an ATP-independent [...]
Nin protein networkhttps://string-db.org/network/10090.ENSMUSP00000152240Ninein; Centrosomal protein required for the positioning and anchorage of the microtubule minus-end in epithelial cells. May also act as a centrosome maturation factor (By similarity). May play a [...]
Gpatch2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000152284G patch domain-containing protein 2-like.
Prxl2c protein networkhttps://string-db.org/network/10090.ENSMUSP00000152323Peroxiredoxin-like 2C; May regulate positively ERK1/2 signaling and AKT1 activation leading to HIF1A up-regulation with an increased expression of glycolysis genes and enhanced glycolysis.
Ippk protein networkhttps://string-db.org/network/10090.ENSMUSP00000152331Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homo [...]
Rps6kl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152336Ribosomal protein S6 kinase-like 1.
Exoc3l4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152337Exocyst complex component 3-like protein 4; Belongs to the SEC6 family.
Mrpl32 protein networkhttps://string-db.org/network/10090.ENSMUSP0000015234539S ribosomal protein L32, mitochondrial; Belongs to the bacterial ribosomal protein bL32 family.
Zfhx3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152353Zinc finger homeobox protein 3; Transcriptional regulator which can act as an activator or a repressor. Inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. In c [...]
Gm2022 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152354Predicted pseudogene 2022; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 4 [...]
Mtrr protein networkhttps://string-db.org/network/10090.ENSMUSP00000152387Methionine synthase reductase; Involved in the reductive regeneration of cob(I)alamin (vitamin B12) cofactor required for the maintenance of methionine synthase in a functional state. Necessary f [...]
Gtpbp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152412Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit.
Gm16368 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152416Predicted pseudogene 16368; Belongs to the eIF-1A family.
Ccdc85c protein networkhttps://string-db.org/network/10090.ENSMUSP00000152421Coiled-coil domain-containing protein 85C; May play a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity). May p [...]
Btbd7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152426BTB/POZ domain-containing protein 7; Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, [...]
Dmac2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000152430ATP synthase subunit s, mitochondrial; Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP syn [...]
Gm21936 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152437Predicted gene, 21936; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S [...]
Gdi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152454Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
Kcnk10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152473Potassium channel, subfamily K, member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
Noxred1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152486NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase.
Zfyve1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152501Zinc finger FYVE domain-containing protein 1.
Zfp72 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152502Zinc finger protein 72.
Slc6a18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152525Sodium-dependent neutral amino acid transporter B(0)AT3; Functions as a sodium and chloride-dependent neutral amino acid transporter in kidneys. Required CLTRN for cell surface expression and for [...]
Nol8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152536Nucleolar protein 8; Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expressio [...]
Pim2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152537Serine/threonine-protein kinase pim-2; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation [...]
Nudt14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152599Uridine diphosphate glucose pyrophosphatase NUDT14; Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP [...]
Klhl28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152602Kelch-like protein 28.
Sp4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152603Transcription factor Sp4; Binds to GT and GC boxes promoters elements. Probable transcriptional activator. Required for normal male reproductive behavior.
Ftl1-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152609Ferritin light polypeptide 1, pseudogene 1.
Atp5mpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000152618ATP synthase subunit ATP5MPL, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membran [...]
Syt16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152623Synaptotagmin-16; May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent.
Zdhhc22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152660Palmitoyltransferase ZDHHC22; Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane (By similarity). Might also mediate palmitoylat [...]
Gm49359 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152662Predicted gene, 49359.
A030005K14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000152700RIKEN cDNA A030005K14 gene.
Eml5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152709Echinoderm microtubule-associated protein-like 5; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; Belongs to the WD repeat EMAP fam [...]
Sult3a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152718Sulfotransferase; Belongs to the sulfotransferase 1 family.
Trim27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152730Zinc finger protein RFP; E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity; mediates the formation of 'Lys-48'- linked polyubiquitin chains; the functi [...]
Srp54a protein networkhttps://string-db.org/network/10090.ENSMUSP00000152764Signal recognition particle 54A.
Gm48552 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152767Predicted gene, 48552.
Kif28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152770Kinesin-like protein KIF28P; Microtubule-dependent motor protein required for mitochondrion morhology and transport of mitochondria in neuronal cells; Belongs to the TRAFAC class myosin-kinesin A [...]
Tes3-ps protein networkhttps://string-db.org/network/10090.ENSMUSP00000152773DCN1-like protein.
Ccnk protein networkhttps://string-db.org/network/10090.ENSMUSP00000152784Cyclin-K; Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of t [...]
Sirt5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152796NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on tar [...]
Adck1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152821AarF domain-containing protein kinase 1; Appears to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase- independent manner to [...]
Gm5788 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152828Predicted pseudogene 5788; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 4 [...]
Snapc1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000152852Small nuclear RNA-activating complex, polypeptide 1-like.
Nnt-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152868Nicotinamide nucleotide transhydrogenase.
Macc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152883Metastasis-associated in colon cancer 1.
Prl3d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152890Prolactin-3D1; Belongs to the somatotropin/prolactin family.
Lysmd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152940LysM and putative peptidoglycan-binding domain-containing protein 3; Essential for Golgi structural integrity.
Rps24 protein networkhttps://string-db.org/network/10090.ENSMUSP0000015294440S ribosomal protein S24; Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.
Mak protein networkhttps://string-db.org/network/10090.ENSMUSP00000152946Serine/threonine-protein kinase MAK; Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors. Could have an important function in sensory cells an [...]
Hdgfl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152948Hepatoma-derived growth factor-related protein 2; Involved in cellular growth control, through the regulation of cyclin D1 expression (By similarity). Associates with chromatin. Isoform 1 and iso [...]
Ints6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152954Integrator complex subunit 6; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The [...]
Pxk protein networkhttps://string-db.org/network/10090.ENSMUSP00000152987PX domain-containing protein kinase-like protein; Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and [...]
Gm20767 protein networkhttps://string-db.org/network/10090.ENSMUSP00000152988Predicted gene, 20767.
Cenpj protein networkhttps://string-db.org/network/10090.ENSMUSP00000153013Centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in [...]
Fbxo16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153015F-box only protein 16; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
Ccdc66 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153023Coiled-coil domain-containing protein 66; Microtubule-binding protein required for ciliogenesis. May function in ciliogenesis by mediating the transport of proteins like BBS4 to the cilium, but a [...]
Prl7d1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153033Prolactin-7D1; Belongs to the somatotropin/prolactin family.
Ndst2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153036Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosam [...]
Slc34a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153038Sodium-dependent phosphate transport protein 2A; Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the a [...]
Zfp131 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153044Zinc finger protein 131; May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling (By similarity). Plays a role during development and organogenesis as well as in t [...]
Rmi1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153050RecQ-mediated genome instability protein 1; Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA [...]
Hmgcs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153064Hydroxymethylglutaryl-CoA synthase, cytoplasmic; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Actr8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153076Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize (By similarity); Belongs to th [...]
Fezf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153090Fez family zinc finger protein 2; Transcription repressor. Required for the specification of corticospinal motor neurons and other subcerebral projection neurons. May play a role in layer and neu [...]
Ctsm protein networkhttps://string-db.org/network/10090.ENSMUSP00000153101Cathepsin M.
Gm49355 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153106Predicted gene, 49355.
Syt7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153132Synaptotagmin-7.
Nek10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153142Serine/threonine-protein kinase Nek10; Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Mbl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153147Mannose-binding protein A; Calcium-dependent lectin. Plays a role in the innate immune response by binding mannose, fucose and N-acetylglucosamine moieties on different microorganisms and mediati [...]
4833420G17Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000153150Uncharacterized protein C5orf34 homolog.
Atp9b protein networkhttps://string-db.org/network/10090.ENSMUSP00000153157Probable phospholipid-transporting ATPase IIB; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
Trappc8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153183Trafficking protein particle complex 8.
Rin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153189Ras and Rab interactor 1; Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First [...]
Armh2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153199Armadillo-like helical domain-containing 2.
Pcgf5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153206Polycomb group RING finger protein 5; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes [...]
Tspan14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153208Tetraspanin-14; Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10. Negatively regulates ADAM10-mediated cleavage of GP6. Promotes ADAM10-mediated cleavage of CDH5.
Trim38 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153240Tripartite motif-containing 38.
Dsc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153261Desmocollin-3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal [...]
H2bc9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153277Histone H2B type 1-H; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
Smim15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153282Small integral membrane protein 15.
Marveld2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153294MARVEL domain-containing protein 2; Plays a role in the formation of tricellular tight junctions and of epithelial barriers. Required for normal hearing via its role in the separation of the endo [...]
Treml1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153300Trem-like transcript 1 protein; Cell surface receptor that may play a role in the innate and adaptive immune response.
Dok3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153308Docking protein 3; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative [...]
Gas1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153311Growth arrest-specific protein 1; Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
Sorbs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153313Sorbin and SH3 domain-containing protein 1.
Gm11549 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153318Predicted gene 11549.
Cdadc1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153357Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis.
Il3ra protein networkhttps://string-db.org/network/10090.ENSMUSP00000153358Interleukin-3 receptor subunit alpha; In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the other contains the beta subunit also shared [...]
Adamts6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153359A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6.
Smc5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153364Structural maintenance of chromosomes protein 5; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may pro [...]
Gm21731 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153383Predicted gene, 21731.
Cc2d2b protein networkhttps://string-db.org/network/10090.ENSMUSP00000153384Coiled-coil and C2 domain-containing 2B.
Aldh1a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153410Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity [...]
Gm21818 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153413Predicted gene, 21818.
BC147527 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153422Similar to 2-cell-stage, variable group, member 3.
Rmdn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153443Regulator of microtubule dynamics protein 2; Belongs to the RMDN family.
H2bc14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153457Histone H2B type 1-M; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histon [...]
Gm21762 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153466Predicted gene, 21762.
Trip10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153467Cdc42-interacting protein 4; Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosp [...]
Mat1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000153488S-adenosylmethionine synthase isoform type-1; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: [...]
Egr3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153491Early growth response protein 3; Probable transcription factor involved in muscle spindle development; Belongs to the EGR C2H2-type zinc-finger protein family.
Tcstv3 protein networkhttps://string-db.org/network/10090.ENSMUSP000001534962-cell-stage, variable group, member 3.
Olfr1291-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153499Olfactory receptor 1291, pseudogene 1.
Gm21885 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153501Predicted gene, 21885.
Ttc37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153521Tetratricopeptide repeat domain 37.
Arl11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153531ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity).
Extl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153547Exostosin-like 3; Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Important for both skeletal development and hematopoiesis, through the formation of HS proteoglycan [...]
Zscan12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153548Zinc finger and SCAN domain-containing protein 12; May be involved in transcriptional regulation.
Gm7929 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153580Predicted gene 7929.
Kif27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153598Kinesin-like protein KIF27; Plays an essential role in motile ciliogenesis.
Shd protein networkhttps://string-db.org/network/10090.ENSMUSP00000153605SH2 domain-containing adapter protein D; May function as an adapter protein.
Dnmt3c protein networkhttps://string-db.org/network/10090.ENSMUSP00000153622DNA (cytosine-5)-methyltransferase 3C; DNA methyltransferase that specifically methylates the promoters of evolutionarily young retrotransposons in the male germline. De novo methylation and subs [...]
Gm49354 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153636Predicted gene, 49354.
Gm29776 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153646Leishmanolysin-like peptidase.
Ptprm protein networkhttps://string-db.org/network/10090.ENSMUSP00000153662Receptor-type tyrosine-protein phosphatase mu; Involved in cell-cell adhesion through homophilic interactions. May play a key role in signal transduction and growth control.
Fdft1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153671Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway; Belongs to the phytoene/squal [...]
Rnf180 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153678E3 ubiquitin-protein ligase RNF180; E3 ubiquitin-protein ligase which promotes polyubiquitination and degradation by the proteasome pathway of ZIC2.
Gm21188 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153701Predicted gene, 21188.
Ppp1r3g protein networkhttps://string-db.org/network/10090.ENSMUSP00000153702Protein phosphatase 1 regulatory subunit 3G; Glycogen-targeting subunit for protein phosphatase 1 (PP1). Involved in the regulation of hepatic glycogenesis in a manner coupled to the fasting-feed [...]
Vmn1r5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153712Vomeronasal type-1 receptor.
Vmn1r43 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153713Vomeronasal type-1 receptor 43; Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
Wdr27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153717WD repeat-containing protein 27.
Atg14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153718Beclin 1-associated autophagy-related key regulator; Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (By simila [...]
Vmn1r47 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153727Vomeronasal type-1 receptor 47; Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
Ccdc152 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153730Coiled-coil domain-containing 152.
Vmn1r39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153741Vomeronasal type-1 receptor.
Gm44579 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153744Predicted gene 44579.
Vmn1r31 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153749Vomeronasal type-1 receptor.
Cdh12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153750Cadherin-12; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the [...]
Gm49394 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153765Predicted gene, 49394.
Vmn1r167 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153774Vomeronasal type-1 receptor.
Vmn1r210 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153776Vomeronasal type-1 receptor.
Rpl36a-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153782Ribosomal protein L36A, pseudogene 1; Belongs to the eukaryotic ribosomal protein eL42 family.
Vmn1r51 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153783Vomeronasal type-1 receptor 51; Putative pheromone receptor implicated in the regulation of social as well as reproductive behavior; Belongs to the G-protein coupled receptor 1 family.
Vmn1r22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153802Vomeronasal type-1 receptor.
Vmn1r20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153815Vomeronasal type-1 receptor.
Vmn1r214 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153823Vomeronasal type-1 receptor.
Vmn1r73 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153827Vomeronasal type-1 receptor.
Vmn1r40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153836Vomeronasal type-1 receptor 40; Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
Vmn1r33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153840Vomeronasal type-1 receptor.
Styx protein networkhttps://string-db.org/network/10090.ENSMUSP00000153854Serine/threonine/tyrosine interaction protein.
Col20a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153871Collagen alpha-1(XX) chain; Probable collagen protein.
Vmn1r77 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153872Vomeronasal type-1 receptor.
Vmn1r57 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153876Vomeronasal type-1 receptor.
Olfr764-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153893Olfactory receptor.
Vmn1r87 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153894Vomeronasal type-1 receptor.
Klf12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153901Krueppel-like factor 12; Confers strong transcriptional repression to the AP-2-alpha gene. Binds to a regulatory element (A32) in the AP-2-alpha gene promoter.
Olfr844 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153910Olfactory receptor.
Vmn1r199 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153918Vomeronasal type-1 receptor.
Vmn1r198 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153942Vomeronasal type-1 receptor.
Vmn1r80 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153967Vomeronasal type-1 receptor.
Vmn1r90 protein networkhttps://string-db.org/network/10090.ENSMUSP00000153986Vomeronasal type-1 receptor.
Mucl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154005Mucin-like 1.
Vmn1r193 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154007Vomeronasal type-1 receptor.
Lmbrd2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154020G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also r [...]
Cdh9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154022Cadherin-9; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the s [...]
Vmn1r70 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154041Vomeronasal type-1 receptor.
Ppp6r2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154087Serine/threonine-protein phosphatase 6 regulatory subunit 2; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphory [...]
Nek4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154090Serine/threonine-protein kinase Nek4; Required for normal entry into proliferative arrest after a limited number of cell divisions, also called replicative senescence. Required for normal cell cy [...]
Kbtbd6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154099Kelch repeat and BTB (POZ) domain-containing 6.
Ang2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154100Angiogenin-2; Has ribonuclease activity (in vitro). Seems to lack angiogenic activity.
Vmn1r37 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154109Vomeronasal type-1 receptor.
Smim40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154114Small integral membrane protein 40.
Rnase6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154125Ribonuclease K6; Ribonuclease which shows a preference for the pyrimidines uridine and cytosine. Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, inc [...]
Vmn1r220 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154136Vomeronasal type-1 receptor.
Vmn1r217 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154137Vomeronasal type-1 receptor.
Vmn1r175 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154170Vomeronasal type-1 receptor.
Gm49342 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154171Predicted gene, 49342.
Vmn1r44 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154174Vomeronasal type-1 receptor 44; Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
Vmn1r46 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154175Vomeronasal type-1 receptor 46; Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
Vmn1r218 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154191Vomeronasal type-1 receptor.
Rnase12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154201Probable inactive ribonuclease-like protein 12; Does not exhibit any ribonuclease activity; Belongs to the pancreatic ribonuclease family.
Olfr766-ps1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154204Olfactory receptor.
Zfp870 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154207Zinc finger protein 870.
Vmn1r10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154213Vomeronasal type-1 receptor.
Vmn1r9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154215Vomeronasal type-1 receptor.
Vmn1r27 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154236Vomeronasal type-1 receptor.
Dpep2-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154250Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
Ndor1-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154261NADPH-dependent diflavin oxidoreductase 1.
Mill2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154268MHC I-like leukocyte 2 long form; Belongs to the MHC class I family.
Vmn1r52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154275Vomeronasal type-1 receptor 52; Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
Ubr5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154293E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Ubiquitinates acetylated PCK1. Also acts as a regulator of DNA damage response by act [...]
Vmn1r8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154298Vomeronasal type-1 receptor.
ENSMUSP00000154304 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154304Uncharacterized protein; Belongs to the complex I LYR family.
Vmn1r41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154326Vomeronasal type-1 receptor 41; Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
Vmn1r17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154334Vomeronasal type-1 receptor.
Vmn1r181 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154337Vomeronasal type-1 receptor.
Olfr607 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154348Olfactory receptor.
Vmn1r54 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154354Vomeronasal type-1 receptor 54; Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
Ebag9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154361Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting [...]
Vmn1r89 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154366Vomeronasal type-1 receptor.
Vmn1r71 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154381Vomeronasal type-1 receptor.
Dnajc15 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154390DnaJ homolog subfamily C member 15; Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9 (By similarity). Negative regulator of the mitochondrial [...]
Vmn1r24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154405Vomeronasal type-1 receptor.
Vmn1r219 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154415Vomeronasal type-1 receptor.
Tex50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154416Testis-expressed 50.
Vmn1r13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154429Vomeronasal type-1 receptor.
Vmn1r42 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154442Vomeronasal type-1 receptor 42; Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
Vmn1r49 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154456Vomeronasal type-1 receptor 49; Putative pheromone receptor implicated in the regulation of social and reproductive behavior; Belongs to the G-protein coupled receptor 1 family.
Gm39653 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154457Neurosecretory protein GL.
Smim40-ps protein networkhttps://string-db.org/network/10090.ENSMUSP00000154467Small integral membrane protein 40, pseudogene.
Nudcd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154478NudC domain-containing protein 1.
Vmn1r28 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154482Vomeronasal type-1 receptor.
Vmn1r201 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154490Vomeronasal type-1 receptor.
Mcf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154494Mcf.2-transforming sequence.
Vmn1r14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154520Vomeronasal type-1 receptor.
Vmn1r75 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154540Vomeronasal type-1 receptor.
Vmn1r86 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154549Vomeronasal type-1 receptor.
Vmn1r50 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154560Vomeronasal type-1 receptor 50; Putative pheromone receptor implicated in the regulation of social and reproductive behavior; Belongs to the G-protein coupled receptor 1 family.
Vmn1r16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154566Vomeronasal type-1 receptor.
Olfr286 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154601Olfactory receptor.
Vmn1r173 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154603Vomeronasal type-1 receptor.
Vmn1r12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154607Vomeronasal type-1 receptor.
Eppk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154609Epiplakin; Cytoskeletal linker protein that connects to intermediate filaments and controls their reorganization in response to stress. In response to mechanical stress like wound healing, is ass [...]
Vmn1r29 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154612Vomeronasal type-1 receptor.
Gm7324 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154633Predicted gene 7324.
Gprin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154640G protein-regulated inducer of neurite outgrowth 2.
Vmn1r184 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154644Vomeronasal type-1 receptor.
Vmn1r188 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154654Vomeronasal type-1 receptor.
Vmn1r34 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154665Vomeronasal type-1 receptor.
Smim41 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154686Small integral membrane protein 41.
Vmn1r206 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154713Vomeronasal type-1 receptor.
Olfr869 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154723Olfactory receptor.
Rabggta protein networkhttps://string-db.org/network/10090.ENSMUSP00000154725Geranylgeranyl transferase type-2 subunit alpha; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence - [...]
ccdc198 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154726Uncharacterized protein CCDC198.
Olfr1358 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154751Olfactory receptor 1358.
Vmn1r215 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154763Vomeronasal type-1 receptor.
Vmn1r185 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154816Vomeronasal type-1 receptor.
Csf2rb protein networkhttps://string-db.org/network/10090.ENSMUSP00000154836Cytokine receptor common subunit beta; High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
9930104L06Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000154851Uncharacterized protein C1orf109 homolog.
St3gal1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154853CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; Responsible for the synthesis of the sequence NeuAc-alpha- 2,3-Gal-beta-1,3-GalNAc- found on sugar chains O-linked to Thr [...]
Tmem274 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154867Transmembrame protein 274.
Nfam1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154945NFAT activation molecule 1; May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcript [...]
Acap2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000154983Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).
Fam118a protein networkhttps://string-db.org/network/10090.ENSMUSP00000154985Protein FAM118A; Belongs to the FAM118 family.
Wnt7b protein networkhttps://string-db.org/network/10090.ENSMUSP00000155014Protein Wnt-7b; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway. Required for normal fusion of the c [...]
Amigo2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155019Amphoterin-induced protein 2; Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIG [...]
Gm49450 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155021Predicted gene, 49450.
Mgrn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155034E3 ubiquitin-protein ligase MGRN1; E3 ubiquitin-protein ligase. Mediates TSG101 monoubiquitination at multiple sites. Plays a role in the regulation of endosome-to-lysosome trafficking. Impairs M [...]
Tmem249 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155040Transmembrane protein 249.
Myh11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155052Myosin-11; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Bik protein networkhttps://string-db.org/network/10090.ENSMUSP00000155083Bcl-2-interacting killer; Accelerates programmed cell death. Binding to the apoptosis repressors Bcl-X(L), BHRF1 or Bcl-2 suppresses this death-promoting activity.
Kansl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155089KAT8 regulatory NSL complex subunit 2; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulatio [...]
Elfn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155111Protein phosphatase 1 regulatory subunit 29; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
Tsta3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155139GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
Nudt16l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155142Tudor-interacting repair regulator protein; Key regulator of TP53BP1 required to stabilize TP53BP1 and regulate its recruitment to chromatin. In absence of DNA damage, interacts with the tandem T [...]
Sco2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155150Protein SCO2 homolog, mitochondrial; Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu [...]
Dnm1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000155155Dynamin-1-like protein; Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the sci [...]
Sec14l5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155164SEC14-like 5 (S. cerevisiae).
Enthd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155166ENTH domain-containing 1.
Nr4a1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155225Nuclear receptor subfamily 4 group A member 1; Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the N [...]
Gm5478 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155269Predicted pseudogene 5478; Belongs to the intermediate filament family.
Polr2f protein networkhttps://string-db.org/network/10090.ENSMUSP00000155332DNA-directed RNA polymerases I, II, and III subunit RPABC2; DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Com [...]
Ddit3-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155363DNA damage-inducible transcript 3 protein.
Rbfox1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155364RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulate [...]
Troap protein networkhttps://string-db.org/network/10090.ENSMUSP00000155404Tastin; Could be involved with bystin and trophinin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo [...]
Slc39a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155442Zinc transporter ZIP4; Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability. Belongs to the ZIP transporter (TC 2.A.5) family.
Phf20l1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155487PHD finger protein 20-like protein 1.
Cacnb3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155514Voltage-dependent L-type calcium channel subunit beta-3; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Increases CACNA1B peak calcium current [...]
Ppp1r16a protein networkhttps://string-db.org/network/10090.ENSMUSP00000155515Protein phosphatase 1 regulatory subunit 16A; Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates.
Socs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155530Suppressor of cytokine signaling 1; SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of [...]
Gtse1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155552G2 and S phase-expressed protein 1; May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpressio [...]
Sox10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155574Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturatio [...]
Smug1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155594Single-strand selective monofunctional uracil DNA glycosylase; Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for [...]
Zfp7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155599Zinc finger protein 7.
Rpl8 protein networkhttps://string-db.org/network/10090.ENSMUSP0000015565760S ribosomal protein L8; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL2 family.
Tfcp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155683Alpha-globin transcription factor CP2; Binds a variety of cellular promoters including fibrinogen, alpha-globin promoters. Activation of the alpha-globin promoter in erythroid cells is via synerg [...]
Zfp647 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155685Zinc finger protein 250; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
Ppil2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155861RING-type E3 ubiquitin-protein ligase PPIL2; Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin [...]
Fetub protein networkhttps://string-db.org/network/10090.ENSMUSP00000155898Fetuin-B; Protease inhibitor required for egg fertilization. Required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a p [...]
Gm49630 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155918Predicted gene, 49630.
Gm17783 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155928ISEC2 protein, intestinal secretory cell protein 2.
Gsc2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155932Homeobox protein goosecoid-2; May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TAATCC; Belongs to the paired homeobox family. Bicoid subf [...]
Ccdc188 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155981Coiled-coil domain-containing 188.
Trat1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155986T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
Pacsin1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000155999Protein kinase C and casein kinase substrate in neurons protein 1; Binds to membranes via its F-BAR domain and mediates membrane tubulation. Plays a role in the reorganization of the microtubule [...]
Cd80 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156031T-lymphocyte activation antigen CD80; Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 o [...]
Crybg3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156047Beta/gamma crystallin domain-containing protein 3.
Pi4ka protein networkhttps://string-db.org/network/10090.ENSMUSP00000156049Phosphatidylinositol 4-kinase alpha; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,- trisphosphate; Belongs to the PI3 [...]
Tbx1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156061T-box transcription factor TBX1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries.
A630089N07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000156068RIKEN cDNA A630089N07 gene.
Map3k13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156075Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activat [...]
Rnaset2a protein networkhttps://string-db.org/network/10090.ENSMUSP00000156083Ribonuclease T2A.
Gm49601 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156088Predicted gene, 49601; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
Senp5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156109Sentrin-specific protease 5; Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targ [...]
Vmn2r95 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156117Vomeronasal 2, receptor 95.
Ube2l3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156121Ubiquitin-conjugating enzyme E2 L3; Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing [...]
Dppa2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156143Developmental pluripotency-associated protein 2; Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status [...]
Ttc3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156151E3 ubiquitin-protein ligase TTC3; E3 ubiquitin-protein ligase which catalyzes the formation of 'Lys-48'-polyubiquitin chains (By similarity). Mediates the ubiquitination and subsequent degradatio [...]
D16Ertd472e protein networkhttps://string-db.org/network/10090.ENSMUSP00000156198Protein EURL homolog; Plays a role in cortical progenitor cell proliferation and differentiation. Promotes dendritic spine development of post-migratory cortical projection neurons by modulating [...]
Hmga1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156199High mobility group AT-hook 1.
Gm20741 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156212Predicted gene, 20741.
Hspbap1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156217HSPB1-associated protein 1; May play a role in cellular stress response.
Cyp2ab1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156220Cytochrome P450, family 2, subfamily ab, polypeptide 1; Belongs to the cytochrome P450 family.
Zdhhc23 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156253Palmitoyltransferase ZDHHC23; Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane. May be involved in NOS1 regulation and targeti [...]
Gm49711 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156255Predicted gene, 49711.
Slc35g3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156297Solute carrier family 35 member G3.
Bex6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156333Protein BEX6.
Stfa1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156337Stefin-1; This is an intracellular thiol proteinase inhibitor; Belongs to the cystatin family.
Atm protein networkhttps://string-db.org/network/10090.ENSMUSP00000156344Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A l [...]
Fst protein networkhttps://string-db.org/network/10090.ENSMUSP00000156375Follistatin; Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
Mapk13 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156387Mitogen-activated protein kinase 13; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an [...]
Crisp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156411Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. Belongs to the CRISP family.
Esp22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156441Exocrine gland-secreted peptide 22; Pheromone produced by juveniles which activates a small number of vomeronasal organ sensory neurons and exhibits a powerful inhibitory effect on adult male mat [...]
Zfp983 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156443Zinc finger protein 983.
Emilin2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156446EMILIN-2; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vesse [...]
Gm7072 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156489Predicted gene 7072.
Qk protein networkhttps://string-db.org/network/10090.ENSMUSP00000156511Protein quaking; RNA-binding protein that plays a central role in myelinization. Also required for visceral endoderm function and blood vessel development. Binds to the 5'-NACUAAY-N(1,20)- UAAY-3 [...]
Esp24 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156516Exocrine gland-secreting peptide 24.
Vmn1r226 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156517Vomeronasal type-1 receptor.
Treml2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156527Trem-like transcript 2 protein; Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counter-receptor for CD276 and interaction with CD276 on T-cells e [...]
Lrrc73 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156533Leucine-rich repeat-containing 73.
Gm5698 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156551Predicted gene 5698.
Vmn1r227 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156554Vomeronasal type-1 receptor.
Cdkn1a protein networkhttps://string-db.org/network/10090.ENSMUSP00000156559Cyclin-dependent kinase inhibitor 1; May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin- dependent kinase activity, [...]
Mea1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156593Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development.
Memo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156607Protein MEMO1; May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays [...]
Vmn1r225 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156633Vomeronasal type-1 receptor.
Vmn1r224 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156636Vomeronasal type-1 receptor.
Erg protein networkhttps://string-db.org/network/10090.ENSMUSP00000156669Transcriptional regulator ERG; Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of [...]
Vmn1r228 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156690Vomeronasal type-1 receptor.
Snrpc protein networkhttps://string-db.org/network/10090.ENSMUSP00000156707U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNR [...]
4930523C07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000156718RIKEN cDNA 4930523C07 gene.
Setd4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156723SET domain-containing protein 4; Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD4 family.
Tjp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156728Tight junction protein ZO-2; Plays a role in tight junctions and adherens junctions.
Zfp53 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156751KRAB-containing zinc-finger protein KRAZ1.
Bicdl2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156752BICD family-like cargo adapter 2.
Unc93a protein networkhttps://string-db.org/network/10090.ENSMUSP00000156756Protein unc-93 homolog A.
Armc12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156794Armadillo repeat-containing protein 12.
Vmn2r60 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156805Vomeronasal 2, receptor 60.
Gm4356 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156831Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta a [...]
Prdm9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156841Histone-lysine N-methyltransferase PRDM9; Histone methyltransferase that sequentially mono-, di-, and tri-methylates both 'Lys-4' (H3K4) and 'Lys-36' (H3K36) of histone H3 to produce respectively [...]
Ptp4a1-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156862Protein tyrosine phosphatase 4a1.
Gm49804 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156878Predicted gene, 49804.
Gm49909 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156883Predicted gene, 49909.
4931428L18Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000156897RIKEN cDNA 4931428L18 gene.
Cramp1l protein networkhttps://string-db.org/network/10090.ENSMUSP00000156906Protein cramped-like.
Gpr108 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156910Protein GPR108; Belongs to the LU7TM family.
Kctd20 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156936BTB/POZ domain-containing protein KCTD20; Promotes the phosphorylation of AKT family members.
Lhfpl5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156959LHFPL tetraspan subfamily member 5 protein; In the inner ear, may be a component of the hair cell's mechanotransduction machinery that functionally couples PCDH15 to the transduction channel. Reg [...]
Dcpp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156985Demilune cell and parotid protein 3.
Gm5155 protein networkhttps://string-db.org/network/10090.ENSMUSP00000156991Predicted gene 5155.
Gm17657 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157004Predicted gene, 17657.
Arl14epl protein networkhttps://string-db.org/network/10090.ENSMUSP00000157009ARL14 effector protein-like.
Rab18 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157011Ras-related protein Rab-18; Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain develop [...]
Cdkl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157063Cyclin-dependent kinase-like 4; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Prss30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157077Serine protease 30; Selectively cleaves synthetic peptide substrates of trypsin. Activates the epithelial sodium channel ENaC (By similarity). Belongs to the peptidase S1 family.
Tmem217 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157082Transmembrane protein 217.
Rnf138 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157102E3 ubiquitin-protein ligase RNF138; E3 ubiquitin-protein ligase involved in DNA damage response by promoting DNA resection and homologous recombination. Recruited to sites of double-strand breaks [...]
Elp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157109Elongator complex protein 2; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in trans [...]
Rab36 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157124Ras-related protein Rab-36; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.
Colec12 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157132Collectin-12; Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Binds also to [...]
Mlst8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157137Target of rapamycin complex subunit LST8; Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response [...]
Ttc39c protein networkhttps://string-db.org/network/10090.ENSMUSP00000157144Tetratricopeptide repeat protein 39C; Belongs to the TTC39 family.
Zfp598 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157172E3 ubiquitin-protein ligase ZNF598; E3 ubiquitin-protein ligase that plays a key role in the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translat [...]
Mettl4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157180N(6)-adenine-specific DNA methyltransferase METTL4; N(6)-adenine-specific DNA methyltransferase that mediates methylation of DNA on the 6th position of adenine (N(6)- methyladenosine) and is requ [...]
Osbpl7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157194Oxysterol-binding protein; Belongs to the OSBP family.
Armc4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157197Armadillo repeat-containing protein 4; Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly.
BC004004 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157208Bombesin receptor-activated protein C6orf89 homolog; Exhibits histone deacetylase (HDAC) enhancer properties. May play a role in cell cycle progression and wound repair of bronchial epithelial ce [...]
Atp6v1e2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157221V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intrace [...]
Proc protein networkhttps://string-db.org/network/10090.ENSMUSP00000157269Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions [...]
Sbpl protein networkhttps://string-db.org/network/10090.ENSMUSP00000157273Spermine-binding protein-like.
Hspe1-rs1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157281Heat shock protein 1 (chaperonin 10),-related sequence 1; Belongs to the GroES chaperonin family.
Tpsb2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157286Tryptase beta-2; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Plays a role in innate immunity [...]
Eci1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157291Enoyl-CoA delta isomerase 1, mitochondrial; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.
Vmn2r-ps159 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157307Vomeronasal 2, receptor, pseudogene 159.
Cyp4f40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157311Cytochrome P450, family 4, subfamily f, polypeptide 40; Belongs to the cytochrome P450 family.
Ccdc178 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157323Coiled-coil domain-containing protein 178.
Dcpp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157331Demilune cell and parotid protein 2.
Slc24a4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157352Sodium/potassium/calcium exchanger 4; Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neur [...]
Nars protein networkhttps://string-db.org/network/10090.ENSMUSP00000157402Asparagine--tRNA ligase, cytoplasmic; Catalyzes the attachment of asparagine to tRNA(Asn) in a two- step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the [...]
Asah2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157424Neutral ceramidase soluble form; Plasma membrane ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at neutral pH. Ceramides, sphingosine, and its phosphoryla [...]
Cyp4f17 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157447Cytochrome P450, family 4, subfamily f, polypeptide 17; Belongs to the cytochrome P450 family.
Elovl3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157465Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endopla [...]
Hsf2bp protein networkhttps://string-db.org/network/10090.ENSMUSP00000157466Heat shock factor 2-binding protein; Inhibits BNC1 transcriptional activity during spermatogenesis, probably by sequestering it in the cytoplasm. May be involved in modulating HSF2 activation in [...]
Dnah8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157469Dynein heavy chain 8, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke [...]
Scyl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157476N-terminal kinase-like protein; Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum. Involved in the maintenance of the G [...]
Gal protein networkhttps://string-db.org/network/10090.ENSMUSP00000157515Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small ne [...]
Gm45928 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157518Predicted gene, 45928.
Tkfc protein networkhttps://string-db.org/network/10090.ENSMUSP00000157520ATP-dependent dihydroxyacetone kinase; Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is [...]
Apcdd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157539Protein APCDD1; Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta- catenin. May act via its interaction with Wnt a [...]
B830017H08Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000157543RIKEN cDNA B830017H08 gene.
Rpl17 protein networkhttps://string-db.org/network/10090.ENSMUSP0000015755660S ribosomal protein L17; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL22 family.
Gm29695 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157559LEM domain-containing protein 1.
Vmn1r183 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157576Vomeronasal type-1 receptor.
Vmn1r231 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157578Vomeronasal type-1 receptor.
Vmn1r68 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157627Vomeronasal type-1 receptor.
Ube2w protein networkhttps://string-db.org/network/10090.ENSMUSP00000157633Ubiquitin-conjugating enzyme E2 W; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Specifically monoubiquitinates the N-terminus of various substrat [...]
Vmn1r192 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157643Vomeronasal type-1 receptor.
Otud6b protein networkhttps://string-db.org/network/10090.ENSMUSP00000157661Deubiquitinase OTUD6B; Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of protein synthesis, downstream of mTORC1 (By similarity). May associate with the protei [...]
Prelid2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157706PRELI domain-containing protein 2.
Gramd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157710GRAM domain-containing protein 2B.
Gpam protein networkhttps://string-db.org/network/10090.ENSMUSP00000157722Glycerol-3-phosphate acyltransferase 1, mitochondrial; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Belongs to [...]
Slc29a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157780Equilibrative nucleoside transporter 2; Mediates equilibrative transport of purine and pyrimidine nucleosides, and the purine base hypoxanthine; Belongs to the SLC29A/ENT transporter (TC 2.A.57) [...]
Ptar1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157782Protein prenyltransferase alpha subunit repeat-containing 1.
Fech protein networkhttps://string-db.org/network/10090.ENSMUSP00000157791Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX.
Kif20a protein networkhttps://string-db.org/network/10090.ENSMUSP00000157839Kinesin-like protein KIF20A; Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the centra [...]
Atad1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157842ATPase family AAA domain-containing protein 1; ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learnin [...]
Snhg4 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157844Small nucleolar RNA host gene 4.
Slc14a2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157851Urea transporter 2; Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major rol [...]
Vmn1r232 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157872Vomeronasal type-1 receptor.
Tigd3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157880Tigger transposable element-derived protein 3.
Vmn1r85 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157899Vomeronasal type-1 receptor.
Gm5244 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157906Predicted pseudogene 5244; Belongs to the eukaryotic ribosomal protein P1/P2 family.
Rps14 protein networkhttps://string-db.org/network/10090.ENSMUSP0000015794840S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.
Ankrd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157960Ankyrin repeat domain-containing protein 1; May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardia [...]
Ubxn1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157971UBX domain-containing protein 1; Ubiquitin-binding protein that plays a role in the modulation of innate immune response. Blocks both the RIG-I-like receptors (RLR) and NF-kappa-B pathways. Follo [...]
Vmn1r55 protein networkhttps://string-db.org/network/10090.ENSMUSP00000157984Vomeronasal type-1 receptor.
Vmn1r235 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158023Vomeronasal type-1 receptor.
Nedd4l protein networkhttps://string-db.org/network/10090.ENSMUSP00000158026E3 ubiquitin-protein ligase NEDD4-like; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiq [...]
Gpr22 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158030G-protein coupled receptor 22; Orphan G-protein coupled receptor. Seems to act through a G(i)/G(o) mediated pathway (By similarity). May be involved in ciliogenesis (By similarity).
Vmn1r88 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158066Vomeronasal type-1 receptor.
Slc4a9 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158071Anion exchange protein.
1810055G02Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000158133Uncharacterized protein C11orf24 homolog.
Tsga10ip protein networkhttps://string-db.org/network/10090.ENSMUSP00000158150Testis-specific 10-interacting protein.
Cyb561a3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158186Cytochrome b ascorbate-dependent protein 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron don [...]
Zfand5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158187AN1-type zinc finger protein 5; Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-media [...]
Kctd16 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158201BTB/POZ domain-containing protein KCTD16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter [...]
Pggt1b protein networkhttps://string-db.org/network/10090.ENSMUSP00000158214Geranylgeranyl transferase type-1 subunit beta; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of p [...]
BC031181 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158256UPF0729 protein C18orf32 homolog; May activate the NF-kappa-B signaling pathway.
Cbs protein networkhttps://string-db.org/network/10090.ENSMUSP00000158269Cystathionine beta-synthase; Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L- homocysteine in a beta-replacement reac [...]
Tcerg1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158288Transcription elongation regulator 1; Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a T [...]
V1rd19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158293Vomeronasal type-1 receptor.
Vmn1r237 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158294Vomeronasal type-1 receptor.
Glo1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158296Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional [...]
Ndst1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158312Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosam [...]
Ndfip1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158314NEDD4 family-interacting protein 1; Activates HECT domain-containing E3 ubiquitin-protein ligases, including NEDD4 and ITCH, and consequently modulates the stability of their targets. As a result [...]
Gm50478 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158316Uncharacterized protein.
Tm9sf3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158318Transmembrane 9 superfamily member 3.
Cd226 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158324CD226 antigen; Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T- lymphocyte (CTL) and NK cell. Cell surface receptor for NEC [...]
Nmrk1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158342Nicotinamide riboside kinase 1; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucl [...]
Cystm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158346Cysteine-rich and transmembrane domain-containing protein 1.
Msln protein networkhttps://string-db.org/network/10090.ENSMUSP00000158357Megakaryocyte-potentiating factor; Membrane-anchored forms may play a role in cellular adhesion. Belongs to the mesothelin family.
Pglyrp2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158365N-acetylmuramoyl-L-alanine amidase; May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity; Belo [...]
Txnl1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158375Thioredoxin-like protein 1; Active thioredoxin with a redox potential of about -250 mV.
Gm50367 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158415Predicted gene, 50367.
Pdcd1lg2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158422Programmed cell death 1 ligand 2; Involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell [...]
Tbc1d10c protein networkhttps://string-db.org/network/10090.ENSMUSP00000158437Carabin; Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that als [...]
Cyp4f39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158442Cytochrome P450, family 4, subfamily f, polypeptide 39; Belongs to the cytochrome P450 family.
Vmn1r233 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158452Vomeronasal type-1 receptor.
Lman1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158495Protein ERGIC-53; Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of [...]
Paip2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158496Polyadenylate-binding protein-interacting protein 2; Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediate [...]
Vps37c protein networkhttps://string-db.org/network/10090.ENSMUSP00000158500Vacuolar protein sorting-associated protein 37C; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into mu [...]
Dipk1c protein networkhttps://string-db.org/network/10090.ENSMUSP00000158524Divergent protein kinase domain 1C; Belongs to the DIPK family.
H2-Eb1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158533H-2 class II histocompatibility antigen, E-B beta chain; Belongs to the MHC class II family.
Fth1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158539Ferritin heavy chain, N-terminally processed; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrou [...]
Ndufs8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158541NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the [...]
Ubash3a protein networkhttps://string-db.org/network/10090.ENSMUSP00000158544Ubiquitin-associated and SH3 domain-containing protein A; Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target [...]
Rpusd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158547RNA pseudouridylate synthase domain-containing protein 1; Belongs to the pseudouridine synthase RluA family.
Gm550 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158551Predicted gene 550.
Atp5md protein networkhttps://string-db.org/network/10090.ENSMUSP00000158561ATP synthase membrane subunit DAPIT, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the [...]
Ppp1r32 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158578Protein phosphatase 1 regulatory subunit 32.
Prr33 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158581Proline-rich protein 33.
Btbd35f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158585BTB domain containing 35, family member 1.
Tmem250-ps protein networkhttps://string-db.org/network/10090.ENSMUSP00000158596Transmembrane protein 250, pseudogene.
Gpr141b protein networkhttps://string-db.org/network/10090.ENSMUSP00000158601G protein-coupled receptor 141B.
Zfp469 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158621Zinc finger protein 469.
Muc19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158627Mucin-19; May function in ocular mucus homeostasis.
Gm21953 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158629Predicted gene, 21953.
Lsmem2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158647Leucine-rich single-pass membrane protein 2.
6330403K07Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000158674RIKEN cDNA 6330403K07 gene.
4933427D14Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000158687RIKEN cDNA 4933427D14 gene.
Spin2e protein networkhttps://string-db.org/network/10090.ENSMUSP00000158691Spindlin family, member 2E.
Sptbn5 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158705Spectrin beta, non-erythrocytic 5.
Cct6a protein networkhttps://string-db.org/network/10090.ENSMUSP00000158738T-complex protein 1 subunit zeta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex [...]
Wdr88 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158765WD_REPEATS_REGION domain-containing protein.
Gm5965 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158767Predicted gene 5965.
Gpr52 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158769G-protein coupled receptor 52; G- protein coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (By similarity). May play a r [...]
Sh3d19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158775SH3 domain-containing protein 19; May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced [...]
Btbd35f19 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158776BTB domain containing 35, family member 19.
Dnah14 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158787Dynein, axonemal, heavy chain 14.
Calm1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158788Calmodulin-1; Belongs to the calmodulin family.
Btbd35f30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158815BTB domain containing 35, family member 30.
1810020O05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000158817Riken cDNA 1810020O05 gene.
Il11ra2-3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158819Interleukin 11 receptor, alpha chain 2.
Magt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158823Magnesium transporter protein 1; Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked o [...]
Ccdc30 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158825Coiled-coil domain-containing protein 30.
Zfp869 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158827Zinc finger protein 869.
Gm8251 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158837Predicted gene 8251.
Mgam2-ps protein networkhttps://string-db.org/network/10090.ENSMUSP00000158841Maltase-glucoamylase 2, pseudogene.
Gm50457 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158848G_PROTEIN_RECEP_F1_2 domain-containing protein.
Gm21411 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158852Predicted gene, 21411.
Zcwpw2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158867Zinc finger CW-type PWWP domain protein 2 homolog.
Tmem205 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158874Transmembrane protein 205.
Cyp2c40 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158887Cytochrome P450 2C40; A cytochrome P450 monooxygenase that may play a major role in the metabolism of arachidonic acid in the intestinal tract. Exhibits regioselective hydroxylase and epoxidase a [...]
Gm34066 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158889Predicted gene, 34066.
Fam161a protein networkhttps://string-db.org/network/10090.ENSMUSP00000158891Protein FAM161A; Involved in ciliogenesis.
Olfr560 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158910Olfactory receptor.
Chrna3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158914Neuronal acetylcholine receptor subunit alpha-3; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-con [...]
Zswim6 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158926Zinc finger SWIM domain-containing protein 6; involved in nervous system development, important for striatal morphology and motor regulation.
Arl5b protein networkhttps://string-db.org/network/10090.ENSMUSP00000158934ADP-ribosylation factor-like protein 5B; Binds and exchanges GTP and GDP.
Fam90a1b-2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158935Uncharacterized protein.
Nat8f1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158936Probable N-acetyltransferase CML1; May play a role in regulation of gastrulation. Belongs to the camello family.
ENSMUSP00000158939 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158939CLLAC domain-containing protein.
Arhgap39 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158945Rho GTPase-activating protein 39.
6330411D24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000158956RIKEN cDNA 6330411D24 gene.
1810058I24Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000158958Short transmembrane mitochondrial protein 1.
Tctn2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158959Tectonic-2; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between t [...]
Clec2f protein networkhttps://string-db.org/network/10090.ENSMUSP00000158978C-type lectin domain family 2 member F.
Slc1a7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158982Excitatory amino acid transporter 5; Transports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate [...]
Tmem134 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158987Transmembrane protein 134; Belongs to the TMEM134/TMEM230 family.
Apof protein networkhttps://string-db.org/network/10090.ENSMUSP00000158988Apolipoprotein F; Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Als [...]
Egfl7 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158990Epidermal growth factor-like protein 7; Regulates vascular tubulogenesis in vivo. Inhibits platelet- derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial [...]
ENSMUSP00000158993 protein networkhttps://string-db.org/network/10090.ENSMUSP00000158993Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family.
A930003A15Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000159001RIKEN cDNA A930003A15 gene.
1700028K03Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000159004Uncharacterized protein C1orf146 homolog.
Gm4125 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159029Predicted gene 4125.
Emc10 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159045ER membrane protein complex subunit 10; Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activ [...]
Chst8 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159050Carbohydrate sulfotransferase 8; Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesi [...]
Catspere1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159061Cation channel sperm-associated protein subunit epsilon; Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for spe [...]
Amz2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159063Archaemetzincin-2; Zinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze neurogranin nor angiotensin-2 (By similarity); Belongs to the peptidase M54 family.
ETV3L protein networkhttps://string-db.org/network/10090.ENSMUSP00000159067ETS variant 3 like.
4930563E22Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000159068Uncharacterized protein C17orf100 homolog.
C5ar2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159074C5a anaphylatoxin chemotactic receptor 2; Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C [...]
Gm31160 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159075Uncharacterized protein.
Atpaf2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159091ATP synthase mitochondrial F1 complex assembly factor 2; May play a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase).
Cgn protein networkhttps://string-db.org/network/10090.ENSMUSP00000159109Cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier; Belongs to the cingulin family.
Foxi2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159111Forkhead box protein I2; Possible transcriptional activator.
Gla protein networkhttps://string-db.org/network/10090.ENSMUSP00000159121Alpha-galactosidase A.
Amd1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159133S-adenosylmethionine decarboxylase 1 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaini [...]
Fgfbp3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159137Fibroblast growth factor-binding protein 3; Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix g [...]
Ndufb1-ps protein networkhttps://string-db.org/network/10090.ENSMUSP00000159138NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved i [...]
Shld3 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159139Shieldin complex subunit 3; Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex f [...]
Fam183b protein networkhttps://string-db.org/network/10090.ENSMUSP00000159142Protein FAM183B.
Kctd11 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159163BTB/POZ domain-containing protein KCTD11; Plays a role as a marker and a regulator of neuronal differentiation; Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal g [...]
Ptpmt1 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159164Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential in [...]
Clca4a protein networkhttps://string-db.org/network/10090.ENSMUSP00000159165Calcium-activated chloride channel regulator 4A, 110 kDa form; May be involved in mediating calcium-activated chloride conductance.
2310009A05Rik protein networkhttps://string-db.org/network/10090.ENSMUSP00000159173Pigb opposite strand 1.
Amer2 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159188APC membrane recruitment protein 2; Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphos [...]
Gm7609 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159200Predicted pseudogene 7609.
LOC101055758 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159207Predicted gene 7592.
ENSMUSP00000159208 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159208Novel protein.
Thoc2l protein networkhttps://string-db.org/network/10090.ENSMUSP00000159241THO complex subunit 2-like.
ENSMUSP00000159245 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159245Odorant receptor 131-2-like.
ENSMUSP00000159251 protein networkhttps://string-db.org/network/10090.ENSMUSP00000159251Novel protein.